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[Sexuality of the couple during pregnancy after assisted reproductive technology: a comparative study.]
IF 0.6 4区 医学 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2025-01-23 DOI: 10.1016/j.gofs.2025.01.005
Marine Beaumont, Mikael Agopiantz, Jeannine Ohl, Marie-Laure Eszto, Cedric Baumann, Matthieu Dap

Objective: To study the sexuality of pregnant women after Assisted Reproductive Technology (ART).

Methods: This was a prospective multicenter study based on two questionnaires: the Female Sexual Function Index (FSFI) and the Couple Satisfaction Index 32 (CSI 32). Two groups were compared: pregnancies following ART and spontaneous pregnancies.

Results: A total of 401 women participated: 215 in the ART group and 186 in the spontaneous pregnancy group. Sexual dysfunction was observed in 49.8% of women in the ART group (n=108/215) and 44.1% in the spontaneous pregnancy group (n=82/186). The FSFI score was not significantly lower in the second trimester (24.0 ± 9.3 for ART vs 25.9 ± 7.3 for spontaneous pregnancy, p=0.07) but was significantly reduced across all trimesters (23.4 ± 9.2 vs 25.4 ± 5.8, p=0.02). Couple relationship quality (CSI 32) was similar between the two groups (134.4 ± 22.2 vs 133.9 ± 23.9, p=0.85). Only 13.9% of ART women (n=30/215) and 8.6% of spontaneous pregnancy women (n=16/186) had discussed their sexuality during pregnancy with a healthcare professional.

Conclusion: The prevalence of sexual dysfunction during pregnancy is high, particularly among women followed for ART. However, the quality of the couple's relationship remains comparable between the two groups.

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引用次数: 0
[The role of mammography in prevention of cardiovascular risk in women].
IF 0.6 4区 医学 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2025-01-23 DOI: 10.1016/j.gofs.2025.01.004
Laëtitia Saccenti, Thu Ha Dao, Vania Tacher
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引用次数: 0
[Reception of oocytes from partner (ROPA) in France: context and perspectives]. [在法国接受来自伴侣的卵母细胞:背景和观点]。
IF 0.6 4区 医学 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2025-01-16 DOI: 10.1016/j.gofs.2025.01.003
Mikaël Agopiantz, Thomas Fréour, Lisa Neumann, Maxime Chaillot, Olivier Morel
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引用次数: 0
[Factors influencing pain during intrauterine device insertion]. [影响宫内节育器置入疼痛的因素]。
IF 0.6 4区 医学 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2025-01-16 DOI: 10.1016/j.gofs.2024.12.007
Chloé Guerry, Hélène Piclet, Florence Bretelle, Julien Mancini, Aubert Agostini, Mallaury Vitabile

Objectives: Fear of pain during intrauterine device (IUD) insertion remains a barrier to its adoption. In the absence of consensus on an optimal pharmacological strategy, it is crucial to determine the factors influencing this pain to reassure and improve the patient experience.

Methods: It was a prospective study conducted in Provence-Alpes-Côte d'Azur between August 2023 and 2024, interviewing adult patients and healthcare professionals during consultations for IUD insertion. The primary outcome studied was the pain experienced during IUD insertion, measured using a numerical rating scale from 0 to 10. After an univariate analysis, a multiple linear regression was performed to identify the factors associated with this pain.

Results: Of the 110 questionnaires analyzed, the average pain score at IUD insertion was 4.1±2.7. Factors associated with pain included European origin, no history of vaginal delivery, apprehension and use of a tenaculum. In contrast, prior IUD insertion, the presence of dysmenorrhea, menstruation at the time of insertion, or premedication had no significant effect on pain. Prior bladder emptying and the use of equimolar mixture of oxygene and nitrous oxide (EMONO) could also be considered as strategies but require further studies.

Conclusion: IUD insertion should be played down, given the moderate and temporary pain it causes. Physicians have a key role in identifying patients at risk of increased pain in order to provide them a personalized approach.

目的:在宫内节育器(IUD)插入时对疼痛的恐惧仍然是其采用的障碍。在缺乏最佳药理学策略共识的情况下,确定影响这种疼痛的因素以保证和改善患者体验是至关重要的。方法:这是一项前瞻性研究,于2023年8月至2024年8月在Provence-Alpes-Côte d'Azur进行,采访了成年患者和咨询宫内节育器插入的医疗保健专业人员。研究的主要结果是宫内节育器插入过程中所经历的疼痛,使用从0到10的数值评分量表进行测量。在单变量分析后,进行多元线性回归以确定与这种疼痛相关的因素。结果:在分析的110份问卷中,宫内节育器插入时的平均疼痛评分为4.1+/- 2.7。与疼痛相关的因素包括欧洲血统、无阴道分娩史、恐惧和使用腱带。相比之下,先前的宫内节育器插入,痛经的存在,插入时的月经,或用药前对疼痛没有显著影响。事先膀胱排空和使用等摩尔氧和一氧化二氮混合物(EMONO)也可以作为策略,但需要进一步研究。结论:考虑到宫内节育器插入引起的中度和暂时的疼痛,应尽量减少。医生在识别有增加疼痛风险的患者方面起着关键作用,以便为他们提供个性化的治疗方法。
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引用次数: 0
[Recommendations for clinical practice: Prevention and management of varicella zoster virus (VZV) infection during pregnancy and the perinatal period (extended version)]. [临床实践建议:妊娠和围产期水痘带状疱疹病毒(VZV)感染的预防和管理(扩展版)]。
IF 0.6 4区 医学 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2025-01-11 DOI: 10.1016/j.gofs.2025.01.001
Caroline Charlier, Olivia Anselem, Marion Caseris, Marie Lachâtre, Asmaa Tazi, Marine Driessen, Didier Pinquier, Chemsa Le Cœur, Aurélie Saunier, Mathilde Bergamelli, Roxane Gibert Vanspranghels, Anaïs Chosidow, Charles Cazanave, Sophie Alain, Karine Faure, André Birgy, François Dubos, Philippe Lesprit, Julie Guinaud, Robert Cohen, Jean-Winoc Decousser, Emmanuel Grimprel, Cyril Huissoud, Julie Blanc, Gilles Kayem, Fanny Vuotto, Christelle Vauloup-Fellous

The Société de Pathologie Infectieuse de Langue Française released in 2024 a new national recommendation for clinical practice on the prevention and management of varicella zoster virus (VZV) infection during pregnancy and the perinatal period. The previous recommendation was issued in 1998, at a time of anti-VZV immunoglobulins shortage; it has hence become obsolete. This recommendation is a formalized expert consensus focusing on infectious diseases management; it is drawn up by a multidisciplinary working group (infectiologists, obstetricians, pediatricians, microbiologists, midwives, hygienists). It has been endorsed by the Collège National des Gynécologues Obstétriciens Français, the Société Française de Médecine Périnatale, the Société Française de Néonatologie, the Collège des Sage-femmes, and the Groupe Infections et Périnatalité of the Société Française de Microbiologie. The aim of this article is to explain and recontextualize the elements of this recommendation.

法国语言病理感染学会于2024年发布了一项关于预防和管理妊娠期和围产期水痘带状疱疹病毒(VZV)感染临床实践的新国家建议。以前的建议是在1998年发布的,当时抗vzv免疫球蛋白短缺;因此,它已经过时了。这一建议是侧重于传染病管理的正式专家共识;它是由一个多学科工作组(传染病学家、产科医生、儿科医生、微生物学家、助产士、卫生学家)起草的。它已经被大学认可国家des Gynecologues Obstetriciens法语,法语的法国医学院Perinatale,法国法国Neonatologie,大学des Sage-femmes, Groupe感染等Perinatalite法国Microbiologie的法国。本文的目的是解释并重新定义该建议的要素。
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引用次数: 0
[How do I do… Clitoral reconstructive surgery after ritual excision in ten steps]. 我该怎么做……仪式切除后的阴蒂重建手术[j]。
IF 0.6 4区 医学 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2025-01-10 DOI: 10.1016/j.gofs.2025.01.002
Erdogan Nohuz, Philippe Chabert, Gautier Chene
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引用次数: 0
[Management of a fetus suspected of differences of sex development (DSD).] [怀疑胎儿性别发育差异(DSD)的处理]
IF 0.6 4区 医学 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2025-01-08 DOI: 10.1016/j.gofs.2024.12.006
Ornella Maltese, Pierre Macé, Alice Faure, Rachel Reynaud, Jean Philippe Bault, Guillaume Gorincour, Edwin Quarello

The management of a fetus suspected of having a variation in genital development is a complex situation. In cases of complete discordance or an unusual appearance of the external genitalia (EG), management always begins with a diagnostic morphological ultrasound. This ultrasound aims to provide detailed imaging of the EG and internal genitalia (IG), focusing on identifying the presence of Müllerian derivatives and detecting any associated malformations. During a multidisciplinary meeting, we should assess the appropriateness of determining the genetic sex through cell-free DNA analysis and to refer the patient to an expert center if necessary.These clinical situations include all atypical presentations of the genital organs with the inability to determine the phenotype, as well as any hypospadias associated with other genital organ involvement. Patients presenting with isolated posterior (or proximal) hypospadias also benefit from an assessment at an expert center. Isolated anterior and middle hypospadias (with negative genetic findings) are excluded from this protocol. Performing an invasive sampling is almost always indicated. The expert center provides the couple with information on the different variations of genital development and the perspectives of managing the child, explaining the recently proposed paradigm shift, according to the new decree of November 15, 2022, in application of Article L-2131-6 of the Public Health Code, which now entails, in some of these situations, delayed surgical management. The diagnostic and prognostic uncertainty of the developmental variation is communicated to the couples. Multidisciplinary care is therefore essential to establish an accurate diagnosis, define the anatomical and functional prognosis, and propose the most appropriate surgical strategy, taking into account the associated morbidities, defining whether or not to adopt a surgical strategy, and providing the most suitable surgical approach, as well as supporting the couple and the child in dealing with this situation.

怀疑胎儿有生殖器发育变异的处理是一个复杂的情况。在完全不一致或外生殖器(EG)的不寻常外观的情况下,管理总是从诊断形态超声开始。该超声旨在提供EG和内生殖器(IG)的详细成像,重点是识别勒氏衍生物的存在和检测任何相关的畸形。在多学科会议期间,我们应该评估通过无细胞DNA分析确定遗传性别的适当性,并在必要时将患者转介到专家中心。这些临床情况包括生殖器器官的所有非典型表现,无法确定表型,以及任何与其他生殖器受累相关的尿道下裂。出现孤立性后(或近端)尿道下裂的患者也可在专家中心进行评估。孤立的前尿道下裂和中尿道下裂(阴性遗传结果)被排除在本方案之外。几乎总是需要进行侵入性取样。专家中心向这对夫妇提供有关生殖发育的不同变化和管理孩子的观点的信息,解释最近提出的范式转变,根据2022年11月15日的新法令,适用于《公共卫生法》第L-2131-6条,现在在某些情况下需要延迟手术治疗。发育变异的诊断和预后的不确定性传达给夫妇。因此,多学科治疗对于建立准确的诊断,确定解剖和功能预后,提出最合适的手术策略,考虑相关的发病率,确定是否采用手术策略,提供最合适的手术方法,以及支持夫妇和孩子处理这种情况至关重要。
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引用次数: 0
[Visions and repercussions of identity-release in oocyte and sperm donors: Descriptive survey among gamete donors]. [卵母细胞和精子捐献者身份释放的愿景和影响:配子捐献者的描述性调查]。
IF 0.6 4区 医学 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2024-12-31 DOI: 10.1016/j.gofs.2024.12.005
Clémence Cirade, Inès Braham, Jérôme Delotte, Samir Boukaidi, Sarah Dupuis, Adeline Morisot, Valérie Benoit, Nicolas Chevalier

Objectives: The Bioethics Law of August 2nd, 2021 established access to origins for people conceived by gamete donation. Two years after the implementation of this disposition, what is the proportion of former gamete donors informed about access to origins, and what is their position on this matter? What could be the potential repercussions of this new law on them?

Methods: Retrospective single-center cohort study using questionnaires.

Results: When former gamete donors were asked about access to origins, only 53% of oocytes donors and 71% of sperm donors were aware of this measure. When participants were asked about the ideal method of donation, it emerged that 41% of female donors and 47% of male donors were in favour of access to their identifying data for the person resulting from the donation. More than half were in favour of access to non-identifying and medical data. If one day someone conceived from their donation requested access to their identifying data, 62% of oocytes donors and 56% of sperm donors would grant it.

Conclusions: A significant proportion of our participants expressed the desire to benefit from information on possible descendants resulting from their donation. Among the donors interviewed, only half are informed of the legislation introducing access to origins, now two years after its implementation. These results encourage us to strengthen communication efforts around access to origins.

目标:2021年8月2日的《生物伦理法》确立了通过配子捐赠受孕的人获得来源的途径。在执行这一处置两年后,得知获得来源的前配子捐赠者的比例是多少?他们在这个问题上的立场是什么?这项新法律可能对他们产生什么潜在影响?方法:采用问卷调查的回顾性单中心队列研究结果:当前配子捐赠者被问及获得来源时,只有53%的卵母细胞捐赠者和71%的精子捐赠者知道这一措施。当参与者被问及理想的捐赠方式时,41%的女性捐赠者和47%的男性捐赠者赞成获得捐赠对象的身份信息。一半以上的人赞成获取非身份和医疗数据。如果有一天,从他们的捐赠中受孕的人要求访问他们的身份数据,62%的卵母细胞捐赠者和56%的精子捐赠者会同意。结论:我们的参与者中有很大一部分人表示希望从他们捐赠的可能后代的信息中受益。在接受采访的捐助者中,只有一半的人知道关于获取原产地的立法,现在该立法已经实施两年了。这些结果鼓励我们加强关于获取原产地的沟通工作。
{"title":"[Visions and repercussions of identity-release in oocyte and sperm donors: Descriptive survey among gamete donors].","authors":"Clémence Cirade, Inès Braham, Jérôme Delotte, Samir Boukaidi, Sarah Dupuis, Adeline Morisot, Valérie Benoit, Nicolas Chevalier","doi":"10.1016/j.gofs.2024.12.005","DOIUrl":"10.1016/j.gofs.2024.12.005","url":null,"abstract":"<p><strong>Objectives: </strong>The Bioethics Law of August 2nd, 2021 established access to origins for people conceived by gamete donation. Two years after the implementation of this disposition, what is the proportion of former gamete donors informed about access to origins, and what is their position on this matter? What could be the potential repercussions of this new law on them?</p><p><strong>Methods: </strong>Retrospective single-center cohort study using questionnaires.</p><p><strong>Results: </strong>When former gamete donors were asked about access to origins, only 53% of oocytes donors and 71% of sperm donors were aware of this measure. When participants were asked about the ideal method of donation, it emerged that 41% of female donors and 47% of male donors were in favour of access to their identifying data for the person resulting from the donation. More than half were in favour of access to non-identifying and medical data. If one day someone conceived from their donation requested access to their identifying data, 62% of oocytes donors and 56% of sperm donors would grant it.</p><p><strong>Conclusions: </strong>A significant proportion of our participants expressed the desire to benefit from information on possible descendants resulting from their donation. Among the donors interviewed, only half are informed of the legislation introducing access to origins, now two years after its implementation. These results encourage us to strengthen communication efforts around access to origins.</p>","PeriodicalId":56056,"journal":{"name":"Gynecologie Obstetrique Fertilite & Senologie","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142924141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Increasing the cumulative live birth rate: Low-grade blastocysts, potential overlook]. [提高累计活产率:低级别囊胚,潜在忽视]。
IF 0.6 4区 医学 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2024-12-21 DOI: 10.1016/j.gofs.2024.12.003
Elie Mouanes-Abelin, Sophie Brouillet, Fatima Barry, Margaux Anav, Alice Fournier, Anéta Andreeva, Marine Miaille, Tal Anahory, Samir Hamamah

It is now widely recognized that, following prolonged culture, the transfer of a high-quality morphologically graded blastocyst is the preferred strategy in embryo transfer. Low-grade blastocysts are often considered to have a low implantation potential, and their use remains highly limited. We conducted a general review of the literature, including publications from August 2017 to October 2023, to assess the current state of knowledge regarding these embryos, which are generally excluded in routine practice. Our primary outcome measure was the "live birth rate" following the frozen transfer of a low-grade morphologically classified blastocyst according to the Gardner classification. The "miscarriage rates" were also evaluated. The bibliographic research led to the selection of 9 articles. Low-grade blastocysts can result in live births, with rates ranging from 5.97 to 40%, and in the birth of healthy children, which remains the primary goal of assisted reproductive technology. It would therefore be relevant to reconsider the routine use of these embryos.

现在人们普遍认识到,经过长时间的培养,移植一个高质量的形态学分级的囊胚是胚胎移植的首选策略。低级别囊胚通常被认为具有较低的植入潜力,其应用仍然受到高度限制。我们进行了文献综述,包括2017年8月至2023年10月的出版物,以评估关于这些胚胎的知识现状,这些胚胎通常在常规实践中被排除在外。我们的主要结局指标是根据Gardner分类法冷冻移植低级别形态学分类囊胚后的“活产率”。对“流产率”也进行了评估。低级别囊胚可导致活产,产率在5.9%至40%之间,并能生出健康的孩子,这仍然是辅助生殖技术的主要目标。因此,重新考虑这些胚胎的常规使用是有意义的。
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引用次数: 0
[Assesment of anxiety and depression in pregnant women in home care management]. [家庭护理管理中孕妇焦虑和抑郁的评估]。
IF 0.6 4区 医学 Q4 OBSTETRICS & GYNECOLOGY Pub Date : 2024-12-09 DOI: 10.1016/j.gofs.2024.12.002
Anais Malandain, Mathilde Barrois

Objective: This study aims to identify factors associated with depressive and anxious symptomatology in pregnant women hospitalized during the antepartum period in home care management (Hospitalisation à domicile).

Method: This is a quantitative, single-center, observational, and descriptive study that included all French-speaking women hospitalized in the HAD of AP-HP between September 2022 and February 2023. Anxious and depressive symptoms were assessed using the self-administered HADS (Hospital Anxiety and Depression Scale) questionnaire. Analyses were conducted according to two distinct groups, comparing patients with an anxiety or depression scores below 8 on the HADS to those with a score of 8 or above (the threshold set on the questionnaire corresponding to intermediate symptomatology). A second questionnaire created for the study detailed maternal history, pregnancy experience, and lifestyle.

Results: A total of sixty-four women were included from September 20, 2022, to February 15, 2023. Eighteen women (28%) evaluated had anxious symptomatology and thirteen women (20%) had depressive symptomatology. Factors significantly associated with anxiety were poor pregnancy experience (P=0.04), the need for psychological follow-up during pregnancy (P<0.01), country of birth (P=0.022), as well as psychiatric history such as previous consultations with a mental health specialist (P=0.015) and previous psychotropic treatment (P=0.028). Additionally, a history of violence (respectively, P=0.034 and P<0.01) and the women's belief that a consultation with a psychologist would benefit them were also associated with anxious and depressive symptomatology (respectively, P<0.01 and P<0.01) CONCLUSION: Our results highlight the importance and necessity of enhancing the screening and prevention of various mental disorders during pregnancy. It would be interesting to implement organized screening for anxiety, similar to depression, in pregnant women hospitalized at home and for the entire obstetric population.

目的:本研究旨在确定家庭护理管理(住家)产前住院孕妇抑郁和焦虑症状的相关因素。方法:这是一项定量、单中心、观察性和描述性研究,纳入了2022年9月至2023年2月期间因AP-HP HAD住院的所有法语女性。焦虑和抑郁症状评估使用自我管理的HADS(医院焦虑和抑郁量表)问卷。根据两个不同的组进行分析,将HADS得分低于8分的焦虑或抑郁患者与得分为8分或以上的患者进行比较(调查问卷上设定的阈值与中级症状相对应)。第二份调查问卷详细说明了母亲的历史、怀孕经历和生活方式。结果:从2022年9月20日至2023年2月15日,共纳入64名女性。18名女性(28%)有焦虑症状,13名女性(20%)有抑郁症状。与焦虑显著相关的因素是孕期经历不佳(p = 0.04)、孕期需要心理随访(p = 0.04)
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引用次数: 0
期刊
Gynecologie Obstetrique Fertilite & Senologie
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