ACS Applied Materials & Interfaces最新文献_第9页

Performance Regulation and Application Evaluation of Colorless Polyimide for Flexible Displays

IF 9.5 2区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

ACS Applied Materials & Interfaces

Pub Date : 2025-03-05 DOI: 10.1021/acsami.4c22198

Han Zhang, Longlong Chen, Hanshen Xin, Jianhua Zhang

Flexible display technology demands specific characteristics from substrate materials, including a high glass transition temperature, significant optical transparency, strong mechanical properties, and a compatible coefficient of thermal expansion. This research focused on improving the optical, thermal, and mechanical properties of colorless polyimide films by adjusting the ratios of fluorine monomers and investigating various annealing temperatures. This approach provided valuable insights into the relationship between structural characteristics and performance, as well as the impact of annealing temperature on these attributes. To assess the reliability of colorless polyimide films, a chemical vapor deposition method was utilized to deposit buffer layers onto the surface of these films. High-temperature annealing experiments indicated that both excessively high and low thermal expansion coefficient could result in the formation of cracks. Finally, after conducting 200,000 folding tests, it was confirmed that the films displayed excellent mechanical properties, with no cracks observed in the buffer layer. This research could provide important insights for developing new substrate materials in display applications.

{"title":"Performance Regulation and Application Evaluation of Colorless Polyimide for Flexible Displays","authors":"Han Zhang, Longlong Chen, Hanshen Xin, Jianhua Zhang","doi":"10.1021/acsami.4c22198","DOIUrl":"https://doi.org/10.1021/acsami.4c22198","url":null,"abstract":"Flexible display technology demands specific characteristics from substrate materials, including a high glass transition temperature, significant optical transparency, strong mechanical properties, and a compatible coefficient of thermal expansion. This research focused on improving the optical, thermal, and mechanical properties of colorless polyimide films by adjusting the ratios of fluorine monomers and investigating various annealing temperatures. This approach provided valuable insights into the relationship between structural characteristics and performance, as well as the impact of annealing temperature on these attributes. To assess the reliability of colorless polyimide films, a chemical vapor deposition method was utilized to deposit buffer layers onto the surface of these films. High-temperature annealing experiments indicated that both excessively high and low thermal expansion coefficient could result in the formation of cracks. Finally, after conducting 200,000 folding tests, it was confirmed that the films displayed excellent mechanical properties, with no cracks observed in the buffer layer. This research could provide important insights for developing new substrate materials in display applications.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"10 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143546797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Selective Electrochemical Oxidation of Methane to Ethanol over the Co3O4/La2O2CO3 Heterojunction Catalyst

IF 9.5 2区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

ACS Applied Materials & Interfaces

Pub Date : 2025-03-05 DOI: 10.1021/acsami.4c19543

Saifei Wang, Xuan Liu, Yi Zhang, Yubo Zhang, Yahan Wang, Jing Han, Xiaomeng Guo, Erhong Duan

Catalyzing methane (CH₄) at room temperature to value-added products is a promising approach, but high product selectivity remains a challenge. In this study, La₂CoO₃ was used as a precursor to synthesize xLC (xCo₃O₄/La₂CoO₃) by adjusting the molar ratio of Co and La. When glycerol was added for hydrothermal modification, a carbon source was introduced into xLC to form an efficient heterojunction material xLC-C (xCo₃O₄/La₂O₂CO₃) capable of converting CH₄ to ethanol at 2.2 V (vs RHE). Moreover, 3.5LC-C was found to convert CH₄ with a current density difference of up to 17.86 mA/cm² and ethanol yields of 627 μmol/g_cat/h. Density functional theory calculations indicate that the high reactivity results from an increased internal charge distribution following the introduction of La₂O₂CO₃ into the Co₃O₄ system, which provides electron transport and reactive oxygen species to activate the C–H bond. Co₃O₄ serves as the active phase, providing a site for the adsorption and conversion of CH₄. The presence of La₂O₂CO₃ in this study reduces the reaction residence time, thus inhibiting C–C coupling reactions between intermediates such as CH₄ and HCHO, impeding the formation of long-chain alcohols and achieving high product selectivity.

{"title":"Selective Electrochemical Oxidation of Methane to Ethanol over the Co3O4/La2O2CO3 Heterojunction Catalyst","authors":"Saifei Wang, Xuan Liu, Yi Zhang, Yubo Zhang, Yahan Wang, Jing Han, Xiaomeng Guo, Erhong Duan","doi":"10.1021/acsami.4c19543","DOIUrl":"https://doi.org/10.1021/acsami.4c19543","url":null,"abstract":"Catalyzing methane (CH4) at room temperature to value-added products is a promising approach, but high product selectivity remains a challenge. In this study, La2CoO3 was used as a precursor to synthesize xLC (xCo3O4/La2CoO3) by adjusting the molar ratio of Co and La. When glycerol was added for hydrothermal modification, a carbon source was introduced into xLC to form an efficient heterojunction material xLC-C (xCo3O4/La2O2CO3) capable of converting CH4 to ethanol at 2.2 V (vs RHE). Moreover, 3.5LC-C was found to convert CH4 with a current density difference of up to 17.86 mA/cm2 and ethanol yields of 627 μmol/gcat/h. Density functional theory calculations indicate that the high reactivity results from an increased internal charge distribution following the introduction of La2O2CO3 into the Co3O4 system, which provides electron transport and reactive oxygen species to activate the C–H bond. Co3O4 serves as the active phase, providing a site for the adsorption and conversion of CH4. The presence of La2O2CO3 in this study reduces the reaction residence time, thus inhibiting C–C coupling reactions between intermediates such as CH4 and HCHO, impeding the formation of long-chain alcohols and achieving high product selectivity.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"42 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143546817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lymph-Node Inspired Hydrogels Enhance CAR Expression and Proliferation of CAR T Cells

IF 9.5 2区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

ACS Applied Materials & Interfaces

Pub Date : 2025-03-05 DOI: 10.1021/acsami.4c19942

Miquel Castellote-Borrell, Marc Domingo, Francesca Merlina, Huixia Lu, Salut Colell, Mireia Bachiller, Manel Juan, Sonia Guedan, Jordi Faraudo, Judith Guasch

Chimeric antigen receptor (CAR) T therapy has shown unprecedented results in clinical practice, including long-term complete responses. One of the current challenges of CAR T therapy is to optimize its production in order to lower its cost. Currently, the in vivo activation of T cells by dendritic cells is replicated ex vivo using polymeric magnetic beads coated with antibodies to induce polyclonal T cell activation. However, current practice overlooks the importance of the complex environment that constitutes the lymph nodes, in which T cells activate and proliferate in vivo. Hydrogels are an ideal candidate material for mimicking the properties of natural tissues such as lymph nodes. In this study, key conditions of the composition, stiffness, and microarchitecture of hydrogels were experimentally and theoretically investigated to optimize primary human CAR T cell culture, focusing on CAR expression and proliferation. Poly(ethylene glycol)–heparin hydrogels featuring interconnected pores of 120 μm and an intermediate stiffness of 3.1 kPa were identified as the most suitable conditions for promoting CAR T cell expression and expansion. Specifically, these hydrogels increased the percentage of CAR+ cells by 50% and doubled the replication index compared to suspension cultures. In conclusion, these newly engineered hydrogels are an interesting tool to help improve CAR T cell manufacture and ultimately advance toward a broader clinical implementation of CAR T cell therapy.

{"title":"Lymph-Node Inspired Hydrogels Enhance CAR Expression and Proliferation of CAR T Cells","authors":"Miquel Castellote-Borrell, Marc Domingo, Francesca Merlina, Huixia Lu, Salut Colell, Mireia Bachiller, Manel Juan, Sonia Guedan, Jordi Faraudo, Judith Guasch","doi":"10.1021/acsami.4c19942","DOIUrl":"https://doi.org/10.1021/acsami.4c19942","url":null,"abstract":"Chimeric antigen receptor (CAR) T therapy has shown unprecedented results in clinical practice, including long-term complete responses. One of the current challenges of CAR T therapy is to optimize its production in order to lower its cost. Currently, the in vivo activation of T cells by dendritic cells is replicated ex vivo using polymeric magnetic beads coated with antibodies to induce polyclonal T cell activation. However, current practice overlooks the importance of the complex environment that constitutes the lymph nodes, in which T cells activate and proliferate in vivo. Hydrogels are an ideal candidate material for mimicking the properties of natural tissues such as lymph nodes. In this study, key conditions of the composition, stiffness, and microarchitecture of hydrogels were experimentally and theoretically investigated to optimize primary human CAR T cell culture, focusing on CAR expression and proliferation. Poly(ethylene glycol)–heparin hydrogels featuring interconnected pores of 120 μm and an intermediate stiffness of 3.1 kPa were identified as the most suitable conditions for promoting CAR T cell expression and expansion. Specifically, these hydrogels increased the percentage of CAR+ cells by 50% and doubled the replication index compared to suspension cultures. In conclusion, these newly engineered hydrogels are an interesting tool to help improve CAR T cell manufacture and ultimately advance toward a broader clinical implementation of CAR T cell therapy.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"19 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143546819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultra-Tiny Scale Topographical Cues Direct Arabidopsis Root Growth and Development

IF 9.5 2区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

ACS Applied Materials & Interfaces

Pub Date : 2025-03-05 DOI: 10.1021/acsami.4c19726

Mahpara Safdar, Sunho Park, Woochan Kim, Dream Kim, Shinyull Lee, Yeon-Ok Kim, Jangho Kim

Plant growth involves intricate processes, including cell division, expansion, and tissue organization, necessitating innovative technologies that emulate native cell–microenvironment interactions. Herein, we introduce ultra-tiny topographical cues (e.g., patterned micro/nanoscale substrates) that mimic micronanofiber structures found in the plant cell wall. We cultured Arabidopsis on unique cell wall-inspired ultra-tiny cues within specialized chambers that positively influenced various physiological aspects compared to a flat surface. Specifically, we observed bidirectional behavior, favoring maximum primary root growth and thickness on sparse features (e.g., 5 μm) and induced predominant anisotropic root alignment on dense features (e.g., 400–800 nm), with alignment decreasing monotonically as the feature size increased. Additionally, RNA sequencing revealed distinct molecular mechanisms underlying Arabidopsis root growth dynamics in response to these ultra-tiny cues, demonstrating modulation of specific genes involved in root development. Collectively, our findings highlight the potential of ultra-tiny cues to modulate gene expression and plant growth dynamics, offering innovative approaches to enhance agricultural productivity sustainably through feature-size-dependent interactions.

{"title":"Ultra-Tiny Scale Topographical Cues Direct Arabidopsis Root Growth and Development","authors":"Mahpara Safdar, Sunho Park, Woochan Kim, Dream Kim, Shinyull Lee, Yeon-Ok Kim, Jangho Kim","doi":"10.1021/acsami.4c19726","DOIUrl":"https://doi.org/10.1021/acsami.4c19726","url":null,"abstract":"Plant growth involves intricate processes, including cell division, expansion, and tissue organization, necessitating innovative technologies that emulate native cell–microenvironment interactions. Herein, we introduce ultra-tiny topographical cues (e.g., patterned micro/nanoscale substrates) that mimic micronanofiber structures found in the plant cell wall. We cultured Arabidopsis on unique cell wall-inspired ultra-tiny cues within specialized chambers that positively influenced various physiological aspects compared to a flat surface. Specifically, we observed bidirectional behavior, favoring maximum primary root growth and thickness on sparse features (e.g., 5 μm) and induced predominant anisotropic root alignment on dense features (e.g., 400–800 nm), with alignment decreasing monotonically as the feature size increased. Additionally, RNA sequencing revealed distinct molecular mechanisms underlying Arabidopsis root growth dynamics in response to these ultra-tiny cues, demonstrating modulation of specific genes involved in root development. Collectively, our findings highlight the potential of ultra-tiny cues to modulate gene expression and plant growth dynamics, offering innovative approaches to enhance agricultural productivity sustainably through feature-size-dependent interactions.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"67 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143561323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Performance of Solid Oxide Fuel Cells Based on Liquid Hydrocarbon Fuel Reforming Gas: Effect of Cell Structure and Gas Composition

IF 9.5 2区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

ACS Applied Materials & Interfaces

Pub Date : 2025-03-05 DOI: 10.1021/acsami.4c21053

Qunwei Guo, Mengjin Zhong, Jiaqi Geng, Yuan Xue, Jiawen Pan, Chunyan Xiong, Bo Chi, Jian Pu

This work comprehensively analyzed how the thickness of the anode and the fuel gas compositions can alter the durability and electrochemical performance of solid oxide fuel cells (SOFCs) when they are operated on steam-reformed gas of hydrocarbons. The electrochemical tests and surface characterizations on the tested cells indicate that cell performance degradation is primarily associated with anode carbon deposition, which increases with a higher C2 gas content in the reforming gas. Additionally, the gas flow field simulation verified that reducing the anode thickness can effectively increase the surface steam content, thereby reducing carbon deposition and improving the stability of the fuel cell. The electrochemical performance of the cell is improved by the C1 composition in the reformed gas. The presence of CO and CO₂ gases promotes the adsorption of H₂ on the Ni metal surface, thereby reducing the polarization resistance of the anode. Meanwhile, CH₄ can release more energy during electrochemical oxidation, reducing the concentration of polarization. These results underscore the potential of utilizing reformed gases consisting of 70 vol % H₂, nearly 30 vol % CO, CO₂, and trace alkanes to function SOFCs. This approach may enhance power density, broaden fuel options, and provide practical solutions for the advancement and commercialization of SOFC technology.

{"title":"Performance of Solid Oxide Fuel Cells Based on Liquid Hydrocarbon Fuel Reforming Gas: Effect of Cell Structure and Gas Composition","authors":"Qunwei Guo, Mengjin Zhong, Jiaqi Geng, Yuan Xue, Jiawen Pan, Chunyan Xiong, Bo Chi, Jian Pu","doi":"10.1021/acsami.4c21053","DOIUrl":"https://doi.org/10.1021/acsami.4c21053","url":null,"abstract":"This work comprehensively analyzed how the thickness of the anode and the fuel gas compositions can alter the durability and electrochemical performance of solid oxide fuel cells (SOFCs) when they are operated on steam-reformed gas of hydrocarbons. The electrochemical tests and surface characterizations on the tested cells indicate that cell performance degradation is primarily associated with anode carbon deposition, which increases with a higher C2 gas content in the reforming gas. Additionally, the gas flow field simulation verified that reducing the anode thickness can effectively increase the surface steam content, thereby reducing carbon deposition and improving the stability of the fuel cell. The electrochemical performance of the cell is improved by the C1 composition in the reformed gas. The presence of CO and CO2 gases promotes the adsorption of H2 on the Ni metal surface, thereby reducing the polarization resistance of the anode. Meanwhile, CH4 can release more energy during electrochemical oxidation, reducing the concentration of polarization. These results underscore the potential of utilizing reformed gases consisting of 70 vol % H2, nearly 30 vol % CO, CO2, and trace alkanes to function SOFCs. This approach may enhance power density, broaden fuel options, and provide practical solutions for the advancement and commercialization of SOFC technology.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"1 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143546795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhanced Catalytic Activity of Pt Nanostructured Electrodes Deposited by Spark Ablation for Proton Exchange Membrane Fuel Cells

IF 9.5 2区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

ACS Applied Materials & Interfaces

Pub Date : 2025-03-05 DOI: 10.1021/acsami.4c22587

Meenakshi Seshadhri Garapati, Esther de Prado, Viliam Vretenár, Tomáš Kovářík, Tomáš Němec

Catalyst layers play a crucial role in determining the performance of proton exchange membrane fuel cells (PEMFCs). However, the deposition of catalyst layers poses challenges in PEMFC stack production due to the complexity of the fabrication steps. Herein, we present a simplified approach to synthesize Pt nanostructures via spark ablation and simultaneously deposit them onto gas diffusion layers (GDL). The in situ deposited catalyst layers on GDL serve as electrodes for membrane electrode assembly (MEA) fabrication. Moreover, the carrier gas in the spark ablation process significantly influences the nucleation and growth of the Pt nanostructures. Pt nanostructures produced in forming gas (Pt_FG, 95% nitrogen, and 5% hydrogen) exhibit dendritic morphology distinct from those obtained in pure N₂ (Pt_N₂). Investigating the catalytic activity of Pt synthesized in different carrier gases reveals that the Pt_FG catalyst demonstrates enhanced half-wave potential, mass activity, and durability compared to those of Pt_N₂ and commercial Pt-black catalysts. Single-cell measurements evaluate the electrocatalytic activity of the ionomer-free, in situ deposited catalyst layers. The Pt_FG MEA (0.2 mg_Pt cm^–2) achieves a power density of 1285 mW cm^–2 at 70 °C, 200 kPa, approximately 1.8 and 2 times higher than Pt_N₂ and Pt-black MEAs, respectively. Further reduction of the catalyst loading to 0.1 mg_Pt cm^–2 results in the Pt_FG MEA delivering 961 mW cm^–2, indicating enhanced catalytic activity and Pt utilization efficiency. This study provides insights into fabricating catalytic layers using a facile strategy, circumventing the need for catalyst synthesis, ink formation, and electrode coating techniques.

{"title":"Enhanced Catalytic Activity of Pt Nanostructured Electrodes Deposited by Spark Ablation for Proton Exchange Membrane Fuel Cells","authors":"Meenakshi Seshadhri Garapati, Esther de Prado, Viliam Vretenár, Tomáš Kovářík, Tomáš Němec","doi":"10.1021/acsami.4c22587","DOIUrl":"https://doi.org/10.1021/acsami.4c22587","url":null,"abstract":"Catalyst layers play a crucial role in determining the performance of proton exchange membrane fuel cells (PEMFCs). However, the deposition of catalyst layers poses challenges in PEMFC stack production due to the complexity of the fabrication steps. Herein, we present a simplified approach to synthesize Pt nanostructures via spark ablation and simultaneously deposit them onto gas diffusion layers (GDL). The in situ deposited catalyst layers on GDL serve as electrodes for membrane electrode assembly (MEA) fabrication. Moreover, the carrier gas in the spark ablation process significantly influences the nucleation and growth of the Pt nanostructures. Pt nanostructures produced in forming gas (Pt_FG, 95% nitrogen, and 5% hydrogen) exhibit dendritic morphology distinct from those obtained in pure N2 (Pt_N2). Investigating the catalytic activity of Pt synthesized in different carrier gases reveals that the Pt_FG catalyst demonstrates enhanced half-wave potential, mass activity, and durability compared to those of Pt_N2 and commercial Pt-black catalysts. Single-cell measurements evaluate the electrocatalytic activity of the ionomer-free, in situ deposited catalyst layers. The Pt_FG MEA (0.2 mgPt cm–2) achieves a power density of 1285 mW cm–2 at 70 °C, 200 kPa, approximately 1.8 and 2 times higher than Pt_N2 and Pt-black MEAs, respectively. Further reduction of the catalyst loading to 0.1 mgPt cm–2 results in the Pt_FG MEA delivering 961 mW cm–2, indicating enhanced catalytic activity and Pt utilization efficiency. This study provides insights into fabricating catalytic layers using a facile strategy, circumventing the need for catalyst synthesis, ink formation, and electrode coating techniques.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"42 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143546798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biocompatible Poly(acrylic acid-co-methacrylic acid)-Coated Iron Oxide Nanoparticles for Enhanced Adsorption and Antimicrobial Activity of Lasioglossin-III

IF 9.5 2区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

ACS Applied Materials & Interfaces

Pub Date : 2025-03-05 DOI: 10.1021/acsami.4c22603

Marco Reindl, Verena Zach, Sebastian P. Schwaminger

The development of biocompatible and efficient drug delivery platforms is critical for therapeutic applications. This study investigates poly(acrylic acid-co-methacrylic acid)-coated iron oxide nanoparticles [ION@P(AA-co-MAA)] as a delivery system for the cationic antimicrobial peptide lasioglossin-III (LL-III). Iron oxide nanoparticles (IONPs) were synthesized via coprecipitation and analyzed by transmission electron microscopy, dynamic light scattering (DLS), and vibrating sample magnetometry. The coating of IONPs was performed in situ, ensuring strong polymer adhesion to the iron oxide core and functionalization with carboxy groups for peptide adsorption. The hydrodynamic diameter of polymer-coated IONPs was determined by DLS and the polymer coating was confirmed by attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy through functional group signatures. ζ-Potential measurements revealed a strongly negative surface charge under physiological pH suggesting excellent colloidal stability. Investigation of LL-III adsorption on ION@P(AA-co-MAA) demonstrated a fast and efficient loading with 0.82 g/g at the highest investigated concentration (4 g/L LL-II), highlighting a superior adsorption efficiency compared to existing IONPs systems. After three washing steps with PBS, 49% of the peptide remained bound to the nanoparticles, indicating a stable adsorption of LL-III on the particles, markedly outperforming other IONP-based systems. The customizable polymer coating design enabled optimal peptide interactions, ensuring efficient loading and retention. Cytotoxicity studies suggested that both unloaded, and LL-III-loaded nanoparticles are biocompatible with 3T3 and HEK cells. Antimicrobial assays revealed enhanced LL-III efficacy upon nanoparticle adsorption, reducing the minimum inhibitory concentration (MIC) against Escherichia coli from 9.82 μM (free LL-III) to 4.59 μM for LL-III-loaded nanoparticles. These findings highlight ION@P(AA-co-MAA) as a promising drug delivery platform offering biocompatibility and enhanced antimicrobial efficacy laying a solid foundation for the development of advanced nanoparticle-based targeted therapies.

{"title":"Biocompatible Poly(acrylic acid-co-methacrylic acid)-Coated Iron Oxide Nanoparticles for Enhanced Adsorption and Antimicrobial Activity of Lasioglossin-III","authors":"Marco Reindl, Verena Zach, Sebastian P. Schwaminger","doi":"10.1021/acsami.4c22603","DOIUrl":"https://doi.org/10.1021/acsami.4c22603","url":null,"abstract":"The development of biocompatible and efficient drug delivery platforms is critical for therapeutic applications. This study investigates poly(acrylic acid-co-methacrylic acid)-coated iron oxide nanoparticles [ION@P(AA-co-MAA)] as a delivery system for the cationic antimicrobial peptide lasioglossin-III (LL-III). Iron oxide nanoparticles (IONPs) were synthesized via coprecipitation and analyzed by transmission electron microscopy, dynamic light scattering (DLS), and vibrating sample magnetometry. The coating of IONPs was performed in situ, ensuring strong polymer adhesion to the iron oxide core and functionalization with carboxy groups for peptide adsorption. The hydrodynamic diameter of polymer-coated IONPs was determined by DLS and the polymer coating was confirmed by attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy through functional group signatures. ζ-Potential measurements revealed a strongly negative surface charge under physiological pH suggesting excellent colloidal stability. Investigation of LL-III adsorption on ION@P(AA-co-MAA) demonstrated a fast and efficient loading with 0.82 g/g at the highest investigated concentration (4 g/L LL-II), highlighting a superior adsorption efficiency compared to existing IONPs systems. After three washing steps with PBS, 49% of the peptide remained bound to the nanoparticles, indicating a stable adsorption of LL-III on the particles, markedly outperforming other IONP-based systems. The customizable polymer coating design enabled optimal peptide interactions, ensuring efficient loading and retention. Cytotoxicity studies suggested that both unloaded, and LL-III-loaded nanoparticles are biocompatible with 3T3 and HEK cells. Antimicrobial assays revealed enhanced LL-III efficacy upon nanoparticle adsorption, reducing the minimum inhibitory concentration (MIC) against Escherichia coli from 9.82 μM (free LL-III) to 4.59 μM for LL-III-loaded nanoparticles. These findings highlight ION@P(AA-co-MAA) as a promising drug delivery platform offering biocompatibility and enhanced antimicrobial efficacy laying a solid foundation for the development of advanced nanoparticle-based targeted therapies.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"16 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143546799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Three-Photon Direct Laser Writing of the QD-Polymer Metasurface for Large Field-of-View Optical Holography.

IF 8.3 2区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

ACS Applied Materials & Interfaces

Pub Date : 2025-03-05 Epub Date: 2025-02-24 DOI: 10.1021/acsami.4c21233

Jiubin Jue, Kai Li, Chenqi Yi, Dale Xie, Shishuo Li, Zongsong Gan

Conventional metasurface holography based on special structural designs is extremely sensitive to the angle of the incident light. Without complex angle optimization for metasurface units, even a small increase in the angle may lead to a rapid decrease in the diffraction efficiency and loss of imaging information. Moreover, the response spectral range of most metasurface holographies cannot be freely adjusted from ultraviolet to infrared. In this study, we prepare a quantum dot (QD)-polymer material system and introduce 1035 nm three-photon direct laser writing (DLW) technology to fabricate the QD-polymer metasurface for large field-of-view optical holography. Based on the stable light absorption characteristics and insensitivity to the angle of incident light of QDs, we achieve a binary amplitude-only holography with a large field of view of ±70°. Moreover, based on the quantum confinement effect of the QDs, the tunable broadband characteristic of the QD-polymer metasurface holography from the ultraviolet to near-infrared is demonstrated, and the binary amplitude-only holography also shows polarization independence. In addition, based on the QD-polymer material system, we can realize a Pancharatnam-Berry phase holography. DLW-processed QD-polymer metasurfaces have the potential to maintain a long-term stability. This study provides a material system and a versatile and flexible technology for realizing various nanoparticle-polymer metasurface holography with a large field of view and tunable broadband characteristics.

{"title":"Three-Photon Direct Laser Writing of the QD-Polymer Metasurface for Large Field-of-View Optical Holography.","authors":"Jiubin Jue, Kai Li, Chenqi Yi, Dale Xie, Shishuo Li, Zongsong Gan","doi":"10.1021/acsami.4c21233","DOIUrl":"10.1021/acsami.4c21233","url":null,"abstract":"Conventional metasurface holography based on special structural designs is extremely sensitive to the angle of the incident light. Without complex angle optimization for metasurface units, even a small increase in the angle may lead to a rapid decrease in the diffraction efficiency and loss of imaging information. Moreover, the response spectral range of most metasurface holographies cannot be freely adjusted from ultraviolet to infrared. In this study, we prepare a quantum dot (QD)-polymer material system and introduce 1035 nm three-photon direct laser writing (DLW) technology to fabricate the QD-polymer metasurface for large field-of-view optical holography. Based on the stable light absorption characteristics and insensitivity to the angle of incident light of QDs, we achieve a binary amplitude-only holography with a large field of view of ±70°. Moreover, based on the quantum confinement effect of the QDs, the tunable broadband characteristic of the QD-polymer metasurface holography from the ultraviolet to near-infrared is demonstrated, and the binary amplitude-only holography also shows polarization independence. In addition, based on the QD-polymer material system, we can realize a Pancharatnam-Berry phase holography. DLW-processed QD-polymer metasurfaces have the potential to maintain a long-term stability. This study provides a material system and a versatile and flexible technology for realizing various nanoparticle-polymer metasurface holography with a large field of view and tunable broadband characteristics.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":" ","pages":"14520-14526"},"PeriodicalIF":8.3,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143481663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Controlling Self-Oscillation of a Single-Layer Liquid Crystal Elastomer at the Air-Water Interface via Light Programming for Water Strider-Inspired Aquatic Robots.

IF 8.3 2区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

ACS Applied Materials & Interfaces

Pub Date : 2025-03-05 DOI: 10.1021/acsami.5c01140

Qiuyu Chen, Jinhui Huang, Xinran Feng, Hui Xie, Shaobing Zhou

Biomimicking aquatic organisms offers many opportunities for designing intelligent robots that can freely move on water. However, most works were focused on multilayered materials or assembled structures and faced limitations in stability, versatility, and motion navigation. Here, we develop an assembly-free water-strider-like aquatic robot using a single layer of light-programmable liquid-crystal elastomer (LCE) that could be used to create asymmetric structures. The LCE strider mimics both the shape and functions of natural water striders; it is designed with four legs, with the fore and hind legs being programmed respectively via light. Consequently, the LCE strider shows self-oscillation and self-propulsion behaviors on low-grade thermal water with a temperature gradient at the air-water interface, owing to unbalanced changes in the contact areas and tensions between the legs and water. Furthermore, the trajectories of the LCE strider are manipulated by NIR light after selectively depositing polydopamine with photothermal conversion. In this way, path navigation is realized, that is, moving straight and on-demand turning, similar to the movement of natural water striders. This study should inspire the development of soft intelligent robots using shape-morphing materials.

{"title":"Controlling Self-Oscillation of a Single-Layer Liquid Crystal Elastomer at the Air-Water Interface via Light Programming for Water Strider-Inspired Aquatic Robots.","authors":"Qiuyu Chen, Jinhui Huang, Xinran Feng, Hui Xie, Shaobing Zhou","doi":"10.1021/acsami.5c01140","DOIUrl":"https://doi.org/10.1021/acsami.5c01140","url":null,"abstract":"Biomimicking aquatic organisms offers many opportunities for designing intelligent robots that can freely move on water. However, most works were focused on multilayered materials or assembled structures and faced limitations in stability, versatility, and motion navigation. Here, we develop an assembly-free water-strider-like aquatic robot using a single layer of light-programmable liquid-crystal elastomer (LCE) that could be used to create asymmetric structures. The LCE strider mimics both the shape and functions of natural water striders; it is designed with four legs, with the fore and hind legs being programmed respectively via light. Consequently, the LCE strider shows self-oscillation and self-propulsion behaviors on low-grade thermal water with a temperature gradient at the air-water interface, owing to unbalanced changes in the contact areas and tensions between the legs and water. Furthermore, the trajectories of the LCE strider are manipulated by NIR light after selectively depositing polydopamine with photothermal conversion. In this way, path navigation is realized, that is, moving straight and on-demand turning, similar to the movement of natural water striders. This study should inspire the development of soft intelligent robots using shape-morphing materials.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":" ","pages":""},"PeriodicalIF":8.3,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143555280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Space Charges at SrTiO3|Mixed Ionic and Electronic Conducting Oxide Heterojunctions and Their Relation to Defect Chemistry

IF 9.5 2区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

ACS Applied Materials & Interfaces

Pub Date : 2025-03-05 DOI: 10.1021/acsami.4c21843

Claudia Steinbach, Alexander Schmid, Matthäus Siebenhofer, Andreas Nenning, Christoph Rameshan, Markus Kubicek, Juergen Fleig

Mixed ionic and electronic conductors (MIECs) are a highly relevant material class in the field of solid-oxide cells and are, for example, promising candidates for electrodes with fast interfacial reaction kinetics. While there are many studies dealing with the bulk conductivities of such MIECs, models describing the interfaces between two mixed-conducting oxides have been far less developed. This study focuses on the investigation of space charges at the interfaces of the model perovskite SrTiO₃ with different MIECs. Impedance spectroscopic measurements at 500 °C revealed that the MIECs under investigation can be divided into materials leading to negligible (YBa₂Cu₃O_7−δ), moderate [(La,Sr)FeO_3−δ, (La,Sr)CoO_3−δ], and large [(La,Sr)MnO_3−δ, (La,Sr)CrO_3−δ] space charge resistances in SrTiO₃ single crystals. The fundamental cause for these different space charge resistances is different space charge potentials, and we show that these can be determined by various methods with excellent agreement, ranging from X-ray photoelectron spectroscopy to impedance spectroscopy and photovoltage measurements. A model is introduced to correlate the ionic and electronic driving forces determining the space charges and to predict the space charge potentials from the electronic and ionic bulk properties of the corresponding mixed-conducting oxides. This model is also used to relate space charge potentials with reducibilities of MIECs, i.e., transition points from hole to vacancy compensation of an acceptor dopant in defect chemical Brouwer diagrams. The predicted trends are in good agreement with thermodynamic data on defect formation energies from the literature. Accordingly, the given model provides a widely applicable framework to predict and describe the space charge properties of a variety of MIEC heterojunctions.

{"title":"Space Charges at SrTiO3|Mixed Ionic and Electronic Conducting Oxide Heterojunctions and Their Relation to Defect Chemistry","authors":"Claudia Steinbach, Alexander Schmid, Matthäus Siebenhofer, Andreas Nenning, Christoph Rameshan, Markus Kubicek, Juergen Fleig","doi":"10.1021/acsami.4c21843","DOIUrl":"https://doi.org/10.1021/acsami.4c21843","url":null,"abstract":"Mixed ionic and electronic conductors (MIECs) are a highly relevant material class in the field of solid-oxide cells and are, for example, promising candidates for electrodes with fast interfacial reaction kinetics. While there are many studies dealing with the bulk conductivities of such MIECs, models describing the interfaces between two mixed-conducting oxides have been far less developed. This study focuses on the investigation of space charges at the interfaces of the model perovskite SrTiO3 with different MIECs. Impedance spectroscopic measurements at 500 °C revealed that the MIECs under investigation can be divided into materials leading to negligible (YBa2Cu3O7−δ), moderate [(La,Sr)FeO3−δ, (La,Sr)CoO3−δ], and large [(La,Sr)MnO3−δ, (La,Sr)CrO3−δ] space charge resistances in SrTiO3 single crystals. The fundamental cause for these different space charge resistances is different space charge potentials, and we show that these can be determined by various methods with excellent agreement, ranging from X-ray photoelectron spectroscopy to impedance spectroscopy and photovoltage measurements. A model is introduced to correlate the ionic and electronic driving forces determining the space charges and to predict the space charge potentials from the electronic and ionic bulk properties of the corresponding mixed-conducting oxides. This model is also used to relate space charge potentials with reducibilities of MIECs, i.e., transition points from hole to vacancy compensation of an acceptor dopant in defect chemical Brouwer diagrams. The predicted trends are in good agreement with thermodynamic data on defect formation energies from the literature. Accordingly, the given model provides a widely applicable framework to predict and describe the space charge properties of a variety of MIEC heterojunctions.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"47 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143560909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0