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Determination of pesticide residues in oat flour using low-temperature partition extraction and GC–MS analysis 利用低温分区萃取和气相色谱-质谱分析法测定燕麦粉中的农药残留量
IF 2.701 Pub Date : 2024-05-29 DOI: 10.1007/s13197-024-06006-z
Aline Maria Teixeira, Maria Eliana L. R. De Queiroz, Alessandra A. Z. Rodrigues, André Fernando de Oliveira, Vitor Manuel Libardi, Jéssika Faêda de Freitas

A simple method based on solid–liquid extraction with a low-temperature partition (SLE/LTP) and analysis by gas chromatography coupled to mass spectrometry (GC–MS) was optimized and validated for determining residues of the pesticides triadimenol, flutriafol, λ-cyhalothrin, difenoconazole, and azoxystrobin in oat flour. A factorial design was employed to optimize the technique and establish the best conditions for the simultaneous extraction of the analytes. Acetonitrile-sample extraction and its 4 h freezing made it possible to recover the pesticides and clean the extracts in a single step. The limit of detection ranged from 1.72 to 12.9 μg kg−1, and the limit of quantification from 5.73 to 43.0 μg kg−1. These values are below the maximum residue limit (MRL) permitted by National legislation. The recovery percentage fell between 91.7 and 108%, with coefficients of variation under 12%. The validated method was applied to oat flour samples randomly acquired from the local market of Viçosa (Minas Gerais, Brazil) and no residues were detected. The SLE/LTP–GC–MS method proved simple, efficient, selective, and sensitive for determining pesticide residues from oat flour samples, offering a more simplified approach compared to techniques described in the literature.

优化并验证了一种基于固液萃取-低温分区(SLE/LTP)和气相色谱-质谱联用(GC-MS)分析的简便方法,用于测定燕麦粉中农药三唑醇、氟虫腈、λ-氰戊菊酯、苯醚甲环唑和唑菌酯的残留量。为优化该技术并确定同时萃取分析物的最佳条件,采用了因子设计。乙腈-样品萃取及其 4 小时的冷冻使农药的回收和提取物的净化成为可能。检测限为 1.72 至 12.9 μg kg-1,定量限为 5.73 至 43.0 μg kg-1。这些数值都低于国家法律允许的最大残留限量(MRL)。回收率介于 91.7%和 108%之间,变异系数低于 12%。对从维索萨(巴西米纳斯吉拉斯州)当地市场随机获得的燕麦粉样品进行了验证,未检测到任何残留。事实证明,SLE/LTP-GC-MS 方法简单、高效、选择性强、灵敏度高,可用于测定燕麦粉样品中的农药残留,与文献中描述的技术相比,该方法更为简便。
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引用次数: 0
Intelligent modelling of sugarcane juice quality characteristics based on microfluidization processing conditions 基于微流控加工条件的甘蔗汁质量特性智能建模
IF 2.701 Pub Date : 2024-05-27 DOI: 10.1007/s13197-024-05994-2
Ayon Tarafdar, Barjinder Pal Kaur

This investigation employed different ANN infrastructures for predicting the quality of sugarcane juice under varying microfluidization pressures (50–200 MPa) and cycles (1–7) which was previously unexplored. Two hidden layer (HL) activation functions (tansigmoid, logsigmoid) and learning algorithms (LM, GDX) with varying hidden layer neurons (HLNs) were tested to predict the color, total phenol content, total flavonoid content, chlorophyll content, total and reducing sugars, polyphenol oxidase activity, peroxidase activity, sucrose neutral invertase activity, aerobic plate count, yeast and mold count, particle size, sensory score and sedimentation rate of sugarcane juice under different microfluidization processing conditions. Results showed that the combination of LM + logsigmoid, GDX + logsigmoid and GDX + tansigmoid produced > 90% prediction accuracy. Among these models, GDX + tansigmoid exhibited 91.7% accuracy on training, and 96% accuracy on testing using relatively lower number of neurons (10 HLNs), and was therefore selected to predict the quality characteristics of sugarcane juice.

这项研究采用了不同的方差分析网络基础结构来预测不同微流体压力(50-200 兆帕)和周期(1-7)下甘蔗汁的质量,这在以前是没有过的。测试了两种隐层(HL)激活函数(tansigmoid、logsigmoid)和不同隐层神经元(HLN)的学习算法(LM、GDX),以预测不同微流控加工条件下甘蔗汁的颜色、总酚含量、总黄酮含量、叶绿素含量、总糖和还原糖、多酚氧化酶活性、过氧化物酶活性、蔗糖中性转化酶活性、需氧平板计数、酵母和霉菌计数、粒度、感官评分和沉降率。结果表明,LM + logsigmoid、GDX + logsigmoid 和 GDX + tansigmoid 的组合预测准确率为 90%。在这些模型中,GDX + tansigmoid 在使用相对较少的神经元数(10 个 HLN)时,训练准确率为 91.7%,测试准确率为 96%,因此被选来预测甘蔗汁的质量特性。
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引用次数: 0
Enhancing starch hydrolysis in sweet potato (Ipomoea batatas (L.) Lam.) through CaCl2 solution mashing: insights into endogenous amylase activity 通过 CaCl2 溶液捣碎提高甘薯(Ipomoea batatas (L.) Lam.)的淀粉水解能力:对内源性淀粉酶活性的认识
IF 2.701 Pub Date : 2024-05-27 DOI: 10.1007/s13197-024-06008-x
Marina Fernanda da Silva Junges, Daniele Bach, Luiz Gustavo Lacerda, Aline Alberti, Alessandro Nogueira, Ivo Mottin Demiate

Sweet potato (Ipomoea batatas (L.) Lam.) is a tuber root crop with high economical potential and China is responsible for harvesting roughly 70% of the world production. It is relatively easy to cultivate and has high nutritional value, including fiber, vitamins, starch and sugars. Cooking the roots results in deep changes of the carbohydrate profile due to the presence of active endogenous amylases. The objective of the present study was to evaluate the influence of CaCl2 mashing at different temperature-time conditions on the starch hydrolysis by endogenous amylases of sweet potato in order to suggest potential industrial applications. Three thermal treatments were performed with the aid of a Rapid Visco Analyzer (RVA), which allowed programming temperature-time profiles. After the treatments, the sugar analysis was carried out by high performance liquid chromatography (HPLC). Total starch content was measured in the insoluble residue from the hydrolysis and the hydrolysis efficiency was calculated. The results have demonstrated that the presence of CaCl2 enhanced enzyme activity, resulting in higher sugar yields when compared to hydrolysis conducted without CaCl2. The results from the present study are promising to the use of sweet potato to produce bioethanol, maltose syrup and vinegar.

甘薯(Ipomoea batatas (L.) Lam.)是一种经济潜力巨大的块根作物,中国的产量约占世界总产量的 70%。它比较容易种植,营养价值高,包括纤维、维生素、淀粉和糖。由于存在活性内源淀粉酶,烹饪根茎会导致碳水化合物谱发生深刻变化。本研究的目的是评估在不同温度-时间条件下 CaCl2 糖化对甘薯内源淀粉酶水解淀粉的影响,从而提出潜在的工业应用建议。借助快速粘度分析仪(RVA)进行了三次热处理,该分析仪可对温度-时间曲线进行编程。处理后,采用高效液相色谱法(HPLC)进行糖分分析。在水解后的不溶残留物中测量了总淀粉含量,并计算了水解效率。结果表明,与不加 CaCl2 的水解相比,CaCl2 的存在增强了酶的活性,从而提高了糖的产量。本研究的结果有望用于利用甘薯生产生物乙醇、麦芽糖浆和醋。
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引用次数: 0
Long-term storage of pink pepper essential oil microencapsulated by chickpea protein/pectin complexes: volatile release, antioxidant and antimicrobial activities 用鹰嘴豆蛋白/pectin 复合物微胶囊长期储存粉红胡椒精油:挥发性释放、抗氧化和抗菌活性
IF 2.701 Pub Date : 2024-05-27 DOI: 10.1007/s13197-024-06007-y
Poliana Moser, Nathalie Almeida Lopes, Adilson Roberto Locali-Pereira, Vânia Regina Nicoletti

Pink pepper essential oil was microencapsulated with chickpea protein (CP) and chickpea protein/pectin (CP-HMP) by spray drying. The reconstitution and storage properties of the powders were evaluated after drying. The impact of microencapsulation in the volatiles release, antioxidant and antimicrobial activity of oil was evaluated during 135 days of storage. CP resulted in more soluble powders (93.52%), CP/HMP resulted in denser powders (0.39 g/mL) while wall material did not influence the wettability. Free pink pepper essential oil (FEO) showed a slight loss of the predominant terpenes (α-pinene, β-pinene, β-mircene, δ-3-carene and D-limonene) after encapsulation. In general, all samples showed an increase in the volatiles release during storage. The evaluation of mass loss showed that FEO had a high release of volatiles, followed by CP and CP-HMP. The antioxidant activity of the FEO decreased (10.8 μg Trolox/mg of oil) after 135 days of storage, whereas the antioxidant activity of CP (14.9) and CP-HMP (14) increased. Both microcapsules presented antimicrobial activity against Bacillus subtilis and Staphylococcus aureus during storage. CP microcapsules had a strong inhibitory effect against the strains tested, and this advantage was even more evident in long-term storage.

通过喷雾干燥法将粉红胡椒精油与鹰嘴豆蛋白(CP)和鹰嘴豆蛋白/pectin(CP-HMP)进行微囊化。对干燥后粉末的重组和储存特性进行了评估。在 135 天的储存过程中,对微胶囊技术对油的挥发性物质释放、抗氧化和抗菌活性的影响进行了评估。氯化石蜡产生了更多的可溶性粉末(93.52%),氯化石蜡/HMP 产生了更致密的粉末(0.39 克/毫升),而壁材对润湿性没有影响。游离粉红胡椒精油(FEO)在封装后显示出主要萜烯(α-蒎烯、β-蒎烯、β-槲皮烯、δ-3-蒈烯和 D-柠檬烯)的轻微损失。总的来说,所有样品在储存期间的挥发性物质释放量都有所增加。质量损失评估表明,FEO 的挥发性物质释放量较高,其次是 CP 和 CP-HMP。储存 135 天后,FEO 的抗氧化活性下降(10.8 μg Trolox/mg油),而 CP(14.9)和 CP-HMP (14)的抗氧化活性上升。两种微胶囊在储存期间都具有抗枯草杆菌和金黄色葡萄球菌的活性。氯化石蜡微胶囊对所测试的菌株有很强的抑制作用,这种优势在长期储存中更为明显。
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引用次数: 0
Development and validation of paper-based strip method for the detection of formalin in milk 开发和验证检测牛奶中福尔马林的纸带方法
IF 2.701 Pub Date : 2024-05-27 DOI: 10.1007/s13197-024-06003-2
Farin Sayyad, Kamal Gandhi, Rajan Sharma, T. M. Amrutha, Priyae Brath Gautam, C. G. Harshitha

Formalin has been reported to be added to milk to prolong the shelf life of milk. The present study was conducted to develop and validate liquid-phase and paper-based strip methods for the rapid detection of formalin in milk using four different procedures i.e., A, B, C and D. Among all the procedures, procedure A worked successfully both in the liquid-phase and paper-based assays. The developed strip-based method involved the dipping of the strips in milk followed by visualization of change in colour. Formalin adulterated milk gave yellow colour to the strip, while for normal milk, it remained colourless. Limit of detection of developed strips was 0.05% with a response time of 7–8 min. Shelf life of the strips was a minimum of 6 months at both room (30–37 °C) and refrigeration (4 ℃) temperature. The strips can be used both at field as well as household levels for rapid detection of formalin presence in milk with greater sensitivity and hence can contribute in supplying authentic milk to the consumers.

据报道,在牛奶中添加福尔马林可延长牛奶的保质期。本研究采用四种不同的方法(即 A、B、C 和 D),开发并验证了液相和纸带法,用于快速检测牛奶中的福尔马林。所开发的纸条检测法是将纸条浸入牛奶中,然后观察颜色的变化。掺有福尔马林的牛奶会使试纸呈黄色,而正常牛奶则保持无色。检测条的检测限为 0.05%,反应时间为 7-8 分钟。在室温(30-37 °C)和冷藏(4 °C)条件下,检测条的保质期至少为 6 个月。该试剂条既可用于现场,也可用于家庭,以更高的灵敏度快速检测牛奶中是否含有福尔马林,从而有助于向消费者提供真正的牛奶。
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引用次数: 0
A low n-6/n-3 PUFA ratio and high level of dietary ɑ-linolenic acid improves sleep behavior in mice with insomnia 低 n-6/n-3 PUFA 比率和高水平的膳食 ɑ-亚麻酸可改善失眠小鼠的睡眠行为
IF 2.701 Pub Date : 2024-05-27 DOI: 10.1007/s13197-024-06004-1
Jie Zhu, Hua-nan Zhang, Jia-kai Wu, Fei-fei Li, Yu-qing Liu, Er-juan Ning, Li-qin Yu, Shen Liang

Camelina sativa oil (CSO) and Semen Ziziphi Spinosae oil (SZSO) are functional oils that have beneficial effects on brain health. This study evaluated the sedative and hypnotic effects of vegetable oils with various n − 6/n − 3 polyunsaturated fatty acids (PUFA) ratios and ɑ-linolenic acid (ALA) contents to mice. The n − 6/n − 3 PUFA ratios of CSO (CSO:SZSO = 1:0, 1.8 g/kg), SZSO (CSO:SZSO = 0:1, 1.8 g/kg), CSO-SZSO-L (CSO:SZSO = 1:1, 1.8 g/kg), and CSO-SZSO-H (CSO:SZSO = 1:1, 3.6 g/kg) were 0.51, 140, 1.69, and 1.69, respectively. The doses of ALA administered to mice with p-chlorophenylalanine-induced insomnia were approximately 0.64, 50 × 10–4, 0.32, and 0.64 g/kg, respectively. The mice were administered CSO, SZSO, and a low-dose combination of CSO and SZSO for seven days with no obvious hypnotic effects. However, the administration of a high-dose combination of CSO and SZSO significantly prolonged sleep duration in mice with induced insomnia and inhibited the serum levels of corticotropin-releasing hormone, adrenocorticotropic hormone, and cortisol. Interestingly, there were no significant effects on the structure and function of the hippocampal tissue. The results indicated that the anti-insomnia effects of these vegetable oils were positively correlated with a low n − 6/n − 3 PUFA ratio and the absolute amount of ALA.

荠菜油(CSO)和刺五加油(SZSO)是对大脑健康有益的功能性油脂。本研究评估了不同 n - 6/n - 3 多不饱和脂肪酸(PUFA)比例和ɑ-亚麻酸(ALA)含量的植物油对小鼠的镇静和催眠作用。CSO (CSO:SZSO = 1:0, 1.8 g/kg)、SZSO (CSO:SZSO = 0:1, 1.8 g/kg)、CSO-SZSO-L (CSO:SZSO = 1:1, 1.8 g/kg)和 CSO-SZSO-H (CSO:SZSO = 1:1, 3.6 g/kg)的 n - 6/n - 3 多不饱和脂肪酸比率分别为 0.51、140、1.69 和 1.69。对氯苯丙氨酸诱导失眠的小鼠服用的 ALA 剂量分别约为 0.64、50 × 10-4、0.32 和 0.64 克/千克。小鼠连续七天服用 CSO、SZSO 以及 CSO 和 SZSO 的低剂量复合制剂,均无明显催眠效果。然而,给小鼠服用大剂量的 CSO 和 SZSO 复方制剂可明显延长失眠小鼠的睡眠时间,并抑制血清中促肾上腺皮质激素释放激素、促肾上腺皮质激素和皮质醇的水平。有趣的是,对海马组织的结构和功能没有明显影响。结果表明,这些植物油的抗失眠作用与低 n - 6/n - 3 PUFA 比率和 ALA 的绝对量呈正相关。
{"title":"A low n-6/n-3 PUFA ratio and high level of dietary ɑ-linolenic acid improves sleep behavior in mice with insomnia","authors":"Jie Zhu,&nbsp;Hua-nan Zhang,&nbsp;Jia-kai Wu,&nbsp;Fei-fei Li,&nbsp;Yu-qing Liu,&nbsp;Er-juan Ning,&nbsp;Li-qin Yu,&nbsp;Shen Liang","doi":"10.1007/s13197-024-06004-1","DOIUrl":"10.1007/s13197-024-06004-1","url":null,"abstract":"<div><p><i>Camelina sativa</i> oil (CSO) and <i>Semen Ziziphi Spinosae</i> oil (SZSO) are functional oils that have beneficial effects on brain health. This study evaluated the sedative and hypnotic effects of vegetable oils with various n − 6/n − 3 polyunsaturated fatty acids (PUFA) ratios and ɑ-linolenic acid (ALA) contents to mice. The n − 6/n − 3 PUFA ratios of CSO (CSO:SZSO = 1:0, 1.8 g/kg), SZSO (CSO:SZSO = 0:1, 1.8 g/kg), CSO-SZSO-L (CSO:SZSO = 1:1, 1.8 g/kg), and CSO-SZSO-H (CSO:SZSO = 1:1, 3.6 g/kg) were 0.51, 140, 1.69, and 1.69, respectively. The doses of ALA administered to mice with p-chlorophenylalanine-induced insomnia were approximately 0.64, 50 × 10<sup>–4</sup>, 0.32, and 0.64 g/kg, respectively. The mice were administered CSO, SZSO, and a low-dose combination of CSO and SZSO for seven days with no obvious hypnotic effects. However, the administration of a high-dose combination of CSO and SZSO significantly prolonged sleep duration in mice with induced insomnia and inhibited the serum levels of corticotropin-releasing hormone, adrenocorticotropic hormone, and cortisol. Interestingly, there were no significant effects on the structure and function of the hippocampal tissue. The results indicated that the anti-insomnia effects of these vegetable oils were positively correlated with a low n − 6/n − 3 PUFA ratio and the absolute amount of ALA.</p></div>","PeriodicalId":632,"journal":{"name":"Journal of Food Science and Technology","volume":"61 12","pages":"2377 - 2387"},"PeriodicalIF":2.701,"publicationDate":"2024-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141167328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of chrysanthemum extract on physicochemical, sensory, and in vitro digestion of set-type yogurt 菊花提取物对固定型酸奶理化、感官和体外消化的影响
IF 2.701 Pub Date : 2024-05-23 DOI: 10.1007/s13197-024-06000-5
Jun’an Zheng, Xin Li, Hongyue Wang, Di Yang, Jiajun Yin, Xiangrong Zhang

Chrysanthemum (Chrysanthemum morifolium Ramat) contains multiple bioactive substances and presents health benefits. In this study, a chrysanthemum extract (CE) was prepared by heat reflux extraction method and a functional yogurt was fabricated containing CE. According to the results of UPLC-MS/MS, 6 phenolic acids and 13 flavonoids were identified from CE compounds. The physicochemical and functional properties of yogurt during storage were investigated. In addition, rheology, microstructure and simulated digestion of yogurt on Day 1 were analyzed. The results demonstrated that the value of pH, total phenolic and flavonoid content, antioxidant capacity, the polyphenols stability in vitro gastric and intestinal digestion condition in the yogurt were enhanced. The syneresis, titratable acidity and the rate of protein hydrolysis in vitro gastric and intestinal digestion condition in the yogurt were reduced with CE addition. Moreover, the changes of protein network and sensory characteristics of yogurt were also occurred with addition of CE. These findings suggest that the integration of CE with yogurt is a promising way to improve the quality and storage ability of yogurt.

菊花(Chrysanthemum morifolium Ramat)含有多种生物活性物质,对健康有益。本研究采用热回流提取法制备了菊花提取物,并制作了含有菊花提取物的功能性酸奶。根据 UPLC-MS/MS 的结果,从菊花提取物中鉴定出 6 种酚酸和 13 种黄酮类化合物。研究了酸奶在储存过程中的物理化学和功能特性。此外,还分析了第 1 天酸奶的流变学、微观结构和模拟消化。结果表明,酸奶的 pH 值、总酚和类黄酮含量、抗氧化能力、多酚稳定性在体外胃肠消化条件下均有所提高。添加 CE 后,酸奶中的协同作用、可滴定酸度以及蛋白质在体外胃肠消化条件下的水解速度均有所降低。此外,添加 CE 后,酸奶的蛋白质网络和感官特征也发生了变化。这些研究结果表明,CE 与酸奶的结合是提高酸奶质量和贮藏能力的一种可行方法。
{"title":"Effects of chrysanthemum extract on physicochemical, sensory, and in vitro digestion of set-type yogurt","authors":"Jun’an Zheng,&nbsp;Xin Li,&nbsp;Hongyue Wang,&nbsp;Di Yang,&nbsp;Jiajun Yin,&nbsp;Xiangrong Zhang","doi":"10.1007/s13197-024-06000-5","DOIUrl":"10.1007/s13197-024-06000-5","url":null,"abstract":"<div><p>Chrysanthemum (<i>Chrysanthemum morifolium Ramat</i>) contains multiple bioactive substances and presents health benefits. In this study, a chrysanthemum extract (CE) was prepared by heat reflux extraction method and a functional yogurt was fabricated containing CE. According to the results of UPLC-MS/MS, 6 phenolic acids and 13 flavonoids were identified from CE compounds. The physicochemical and functional properties of yogurt during storage were investigated. In addition, rheology, microstructure and simulated digestion of yogurt on Day 1 were analyzed. The results demonstrated that the value of pH, total phenolic and flavonoid content, antioxidant capacity, the polyphenols stability in vitro gastric and intestinal digestion condition in the yogurt were enhanced. The syneresis, titratable acidity and the rate of protein hydrolysis in vitro gastric and intestinal digestion condition in the yogurt were reduced with CE addition. Moreover, the changes of protein network and sensory characteristics of yogurt were also occurred with addition of CE. These findings suggest that the integration of CE with yogurt is a promising way to improve the quality and storage ability of yogurt.</p></div>","PeriodicalId":632,"journal":{"name":"Journal of Food Science and Technology","volume":"61 12","pages":"2343 - 2353"},"PeriodicalIF":2.701,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141104256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tropical fruits as a potential source for the recovery of bioactive compounds: Tamarindus indica L., Annona muricata, Psidium guajava and Mangifera indica 热带水果是回收生物活性化合物的潜在来源:罗望子、菠萝、番石榴和芒果
IF 2.701 Pub Date : 2024-05-22 DOI: 10.1007/s13197-024-05983-5
Mashell A. Toscano Oviedo, Luis A. García Zapateiro, Somaris E. Quintana

The objective of this review is to identify the bioactive compounds present in tropical fruits such as Tamarindus indica L., Annona muricata, Mangifera indica, and Psidium guajava and their biological activities. The identification of these compounds shows their potential as a food ingredient in the development of products, providing added value to them, because not only the pulp of the fruit is used, but also the shell and its other parts, such as the leaves, are used, being viable sources to obtain some compounds that benefit human health. Implementing fruits that have certain bioactive compounds such as carotenoids (β-carotene, α-carotene, lutein, zeaxanthin and β-cryptoxanthin), antioxidants (vitamins A and C), and phenolic compounds (ellagic acid, gallic acid, citric acid) in the production process in the food industry, allows them to become functional foodstuffs. The results obtained show the need to implement the operational processes that allow obtaining different compounds, which ensure their stability and precision, applying different extraction methods such as maceration, Soxhlet, supercritical fluids, and ultrasound.

本综述旨在确定热带水果中的生物活性化合物,如罗望子、莲雾、芒果和番石榴,以及它们的生物活性。对这些化合物的鉴定表明,它们具有作为食品配料开发产品的潜力,为产品提供了附加值,因为不仅使用了水果的果肉,还使用了果壳及其他部分,如叶子,这些都是获得有益于人类健康的某些化合物的可行来源。在食品工业的生产过程中,使用具有某些生物活性化合物的水果,如类胡萝卜素(β-胡萝卜素、α-胡萝卜素、叶黄素、玉米黄质和β-隐黄质)、抗氧化剂(维生素 A 和 C)和酚类化合物(鞣花酸、没食子酸、柠檬酸),可使它们成为功能性食品。研究结果表明,有必要采用不同的萃取方法,如浸渍法、索氏提取法、超临界流体提取法和超声波提取法,以获得不同的化合物,确保其稳定性和精确性。
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引用次数: 0
Automated liquid–liquid deep eutectic solvents based microextraction procedure for determination of acrylamide in foodstuffs by high-performance liquid chromatography with ultraviolet detection 利用高效液相色谱-紫外检测法测定食品中丙烯酰胺含量的基于液-液深共晶溶剂的自动微萃取程序
IF 2.701 Pub Date : 2024-05-22 DOI: 10.1007/s13197-024-05999-x
Andrey Shishov, Ulyana Markova, Davydova Ekaterina, Andrey Bulatov

For the rapid and efficient determination of acrylamide in food products by HPLC-UV, an environmentally friendly analytical approach has been developed, including liquid-phase extraction and subsequent liquid–liquid microextraction using a deep eutectic solvent. To automate the procedure, the flow-through “lab in a syringe” method was used. Acrylamide is considered a potential endocrine disrupting chemical and its main source is fried foods, which are widely consumed by both children and adults. To extract and concentrate acrylamide, hydrophobic deep-eutectic solvents based on various carboxylic acids and natural terpenoids were studied for the first time. It was found that benzoic acid, as a precursor of the extraction solvent, promotes the transfer of hydrophilic acrylamide from the aqueous phase of the sample due to the interaction of carboxyl and amide groups. The procedure has been validated and used effectively to estimate acrylamide content in beetroot and corn chips. Under optimal conditions, the detection limit was 0.01 mg/kg. Unlike existing methods, the proposed method is fully automated, does not require hazardous organic solvents and additional derivatization stages, and at the same time allows the determination of acrylamide at a level below established standards.

为了利用高效液相色谱-紫外法快速有效地测定食品中的丙烯酰胺含量,我们开发了一种环境友好型分析方法,包括液相萃取和随后使用深共晶溶剂的液液微萃取。为了使这一过程自动化,采用了 "注射器中的实验室 "流动法。丙烯酰胺被认为是一种潜在的干扰内分泌的化学物质,其主要来源是儿童和成人广泛食用的油炸食品。为了提取和浓缩丙烯酰胺,首次研究了基于各种羧酸和天然萜类化合物的疏水性深共晶溶剂。研究发现,苯甲酸作为萃取溶剂的前体,由于羧基和酰胺基的相互作用,可促进亲水性丙烯酰胺从样品水相中转移。该方法已通过验证,并可有效用于估算甜菜根和玉米片中的丙烯酰胺含量。在最佳条件下,检测限为 0.01 毫克/千克。与现有方法不同的是,所提出的方法是全自动的,不需要使用有害的有机溶剂和额外的衍生阶段,同时还能测定低于既定标准的丙烯酰胺含量。
{"title":"Automated liquid–liquid deep eutectic solvents based microextraction procedure for determination of acrylamide in foodstuffs by high-performance liquid chromatography with ultraviolet detection","authors":"Andrey Shishov,&nbsp;Ulyana Markova,&nbsp;Davydova Ekaterina,&nbsp;Andrey Bulatov","doi":"10.1007/s13197-024-05999-x","DOIUrl":"10.1007/s13197-024-05999-x","url":null,"abstract":"<div><p>For the rapid and efficient determination of acrylamide in food products by HPLC-UV, an environmentally friendly analytical approach has been developed, including liquid-phase extraction and subsequent liquid–liquid microextraction using a deep eutectic solvent. To automate the procedure, the flow-through “lab in a syringe” method was used. Acrylamide is considered a potential endocrine disrupting chemical and its main source is fried foods, which are widely consumed by both children and adults. To extract and concentrate acrylamide, hydrophobic deep-eutectic solvents based on various carboxylic acids and natural terpenoids were studied for the first time. It was found that benzoic acid, as a precursor of the extraction solvent, promotes the transfer of hydrophilic acrylamide from the aqueous phase of the sample due to the interaction of carboxyl and amide groups. The procedure has been validated and used effectively to estimate acrylamide content in beetroot and corn chips. Under optimal conditions, the detection limit was 0.01 mg/kg. Unlike existing methods, the proposed method is fully automated, does not require hazardous organic solvents and additional derivatization stages, and at the same time allows the determination of acrylamide at a level below established standards. </p></div>","PeriodicalId":632,"journal":{"name":"Journal of Food Science and Technology","volume":"61 12","pages":"2332 - 2342"},"PeriodicalIF":2.701,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s13197-024-05999-x.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141108088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inhibition of hepatic stellate cell activation by nutraceuticals: an emphasis on mechanisms of action 营养保健品抑制肝星状细胞活化:强调作用机制
IF 2.701 Pub Date : 2024-05-18 DOI: 10.1007/s13197-024-06002-3
Vasudevan Sekar, Venkateish VP, Vani Vijay, Annapoorna BR, Nivya Vijayan, Madan Kumar Perumal

Liver diseases emerge as a serious threat to humans worldwide due to increasing morbidity and mortality. Liver disease related deaths accounts for one third of all disease related death globally. A simple fatty liver if unattended advances further to liver fibrosis, cirrhosis and hepatocellular carcinoma. During liver fibrogenesis, hepatic stellate cells gets activated into myofibroblast like cells and exhibit proliferative and fibrogenic features. Targeting these activated hepatic stellate cells offer promising therapeutic approach towards liver fibrosis management. To date there is no Food and Drug Administration approved treatments for liver fibrosis. However, a large number of clinical trials are being conducted employing monoclonal antibodies, drugs, dietary supplements and herbal medicines. A vast number of research findings demonstrated nutraceuticals to be effective against experimental liver fibrosis both in vitro and in vivo. Nutraceuticals typically regulate key signaling pathways in activated hepatic stellate cells and exhibit anti-fibrotic effect. In this review, the mechanistic action of nutraceuticals targeting activated hepatic stellate cells were summarized to establish them as a possible therapeutic candidate for liver fibrosis.

由于发病率和死亡率不断上升,肝脏疾病已成为全球人类面临的严重威胁。全球与肝病相关的死亡人数占所有疾病相关死亡人数的三分之一。单纯性脂肪肝如果不加以重视,会进一步发展为肝纤维化、肝硬化和肝细胞癌。在肝纤维化过程中,肝星状细胞会被活化成类似肌成纤维细胞的细胞,并表现出增殖和纤维化特征。针对这些活化的肝星状细胞提供了治疗肝纤维化的有效方法。迄今为止,尚无食品和药物管理局批准的肝纤维化治疗方法。不过,大量临床试验正在采用单克隆抗体、药物、膳食补充剂和草药。大量研究结果表明,营养保健品在体外和体内都能有效防治实验性肝纤维化。营养保健品通常能调节活化的肝星状细胞中的关键信号通路,并表现出抗纤维化作用。本综述总结了以活化的肝星状细胞为靶点的营养保健品的作用机理,将其确立为治疗肝纤维化的可能候选疗法。
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引用次数: 0
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