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2009 2nd International Conference on Biomedical Engineering and Informatics最新文献

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Numerical Analysis of CSMA/CA for Pattern-Based WBAN System 基于模式的WBAN系统CSMA/CA的数值分析
Pub Date : 2009-10-30 DOI: 10.1109/BMEI.2009.5304962
S. Ullah, Daehan Kwak, Cheolhyo Lee, Hyung-Soo Lee, K. Kwak
This paper presents a numerical analysis of a CSMA/CA mechanism for a pattern-based WBAN system. Several equations are derived to observe the number of back-off periods required by high, medium, and low traffic BAN Nodes (BNs). Numerical results show that CSMA/CA mechanism is not suitable for medium and low traffic BNs, and high traffic BNs encounter heavy collision problems. This suggests the use of a TDMA-based solution that can solve a range of problems including traffic heterogeneity and correlation problems.
本文对基于模式的WBAN系统的CSMA/CA机制进行了数值分析。推导了几个方程来观察高、中、低流量BAN节点(bn)所需的回退周期数。数值结果表明,CSMA/CA机制不适用于中低流量的宽带网络,而高流量的宽带网络会遇到严重的碰撞问题。这表明使用基于tdma的解决方案可以解决一系列问题,包括流量异构性和相关性问题。
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引用次数: 13
Analysis and Research on Data Transmission in Cooperative Software under P2P Model P2P模式下协同软件数据传输的分析与研究
Pub Date : 2009-10-30 DOI: 10.1109/BMEI.2009.5305622
Zhe Zhao, Hongyu Zhou, Lixin Wang
This paper studied on data processing in cooperative software under P2P pattern. It introduced the concrete improvement scheme on data transmission considering the problems of GK-Star model. Transformed the push data model into push-pull model which improved the performance obviously. keyword:P2P Technology �◊ Cooperative Application �◊Cooperative Region �◊Data Processing; data transmission; push data; pull data
本文研究了P2P模式下协同软件中的数据处理问题。针对GK-Star模型存在的问题,介绍了数据传输的具体改进方案。将推数据模型转换为推拉模型,明显提高了性能。关键词:P2P技术;合作应用;合作区域;数据传输;推动数据;提取数据
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引用次数: 0
The Study of Nonlinear Change of Bladder During Urinary Store Based on MRI 基于MRI的储尿过程中膀胱非线性变化研究
Pub Date : 2009-10-30 DOI: 10.1109/BMEI.2009.5305697
Haijun Niu, Lifeng Li, Fengling Ma, F. Pu, Deyu Li, Yubo Fan
It is significant to monitor bladder volume continuously and accurately in many specific clinical conditions or during treatment or management of urological disorders. This study try to explore the dynamic bladder storing process and understand the change of bladder shape and intra-vesical volume under the specific conditions of water-drinking using reconstructed three-dimension (3D) bladder models based on magnetic resonance imaging (MRI). A 3T GE MRI system was used to acquire bladder images while storing in the transverse section. Segmentation of the bladder MRI Image, 3D model reconstruction, and volume measurement in different scan phases were performed with Mimics software. The results showed that the bladder varied from small bowl-like shape to irregular ellipsoid during urinary store. The increase in bladder volume was nonlinear under the specific conditions of water-drinking. The diameter change of the bladder in different directions was inconsistent during urinary store.
在许多特殊的临床条件下或在泌尿系统疾病的治疗或管理过程中,持续准确地监测膀胱容量是非常重要的。本研究试图通过基于磁共振成像(MRI)的重建膀胱三维模型,探索膀胱的动态储存过程,了解特定饮水条件下膀胱形状和膀胱内体积的变化。使用3T GE MRI系统获取膀胱图像,同时存储在横切面上。利用Mimics软件对膀胱MRI图像进行分割、三维模型重建和不同扫描阶段的体积测量。结果表明,膀胱在储尿过程中由小碗状变为不规则椭球状。在特定的饮水条件下,膀胱体积的增加是非线性的。尿潴留过程中不同方向膀胱直径变化不一致。
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引用次数: 0
Detection of the Pulse Waveform Characteristic Points by Wavelet Transform Using Multiscale Differential Operator 基于多尺度微分算子的小波变换脉冲波形特征点检测
Pub Date : 2009-10-30 DOI: 10.1109/BMEI.2009.5305400
Qun Wang, Zhiwen Liu
The pulse waveform characteristic point detection is important for non-invasively detecting cardiovascular parameters. A novel designed algorithm based on wavelet transform (WT) is developed. For some pulse waveforms, characteristic points exactly correspond to the zero-crossing of a wavelet with one vanishing moment, while the others incompletely correspond to. And characteristic points also correspond to the local extrema of a wavelet with two vanishing moment. So an algorithm combining a wavelet with one vanishing moment and another one with two vanishing moment is used to improve the detection rate of characteristic points. The results show that automatic identification of characteristics points has a high rate of accuracy.
脉搏波形特征点检测是无创检测心血管参数的重要手段。提出了一种基于小波变换的新算法。对于某些脉冲波形,特征点完全对应于具有一个消失矩的小波的过零,而其他特征点则不完全对应于。特征点也对应于具有两个消失矩的小波的局部极值。为了提高特征点的检出率,提出了一种单消失矩小波和双消失矩小波相结合的算法。结果表明,特征点的自动识别具有较高的准确率。
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引用次数: 3
A Robust Empirical Bayesian Method for Detecting Differentially Expressed Genes 一种鲁棒经验贝叶斯方法检测差异表达基因
Pub Date : 2009-10-30 DOI: 10.1109/BMEI.2009.5305050
Fugui Wang, Lin Hou, Jiangfeng Xu, M. Qian, Minghua Deng
With the increase in genome-wide experiments and sequenced genomes, the analysis of large data sets has become commonplace in biology. It is often the case that thousands of features in a genome-wide data set are tested against null hypotheses, where only a small number of features are expected to be significant. The empirical Bayesian method (EB) is one of the most powerful methods to address such an issue, which has attracted much attention in literature. Here we propose an altered EB method, which is more robust and gives a more reasonable statistical interpretation. Our method is applied on both simulated and real data, and it outperforms the EB method.
随着全基因组实验和基因组测序的增加,对大数据集的分析在生物学中已经变得司空见惯。通常情况下,全基因组数据集中的数千个特征都是根据零假设进行测试的,其中只有少数特征预计是重要的。经验贝叶斯方法(empirical Bayesian method, EB)是解决这一问题最有力的方法之一,引起了文献的广泛关注。在这里,我们提出了一种改进的EB方法,它更稳健,并给出了更合理的统计解释。我们的方法在模拟和实际数据上都得到了应用,并且优于EB方法。
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引用次数: 0
A Novel Interactive Image Processing Approach for DICOM Medical Image Data DICOM医学图像数据的交互式图像处理新方法
Pub Date : 2009-10-30 DOI: 10.1109/BMEI.2009.5304840
Zhanli Hu, Hairong Zheng, Jianbao Gui
The development of more flexible and accurate medical image processing technique and platform is important requirement for clinical diagnosis and treatment. A new interactive image processing method is proposed in this work. Using this method, image smoothing, sharpening, histogram processing, pseudo-color processing, segmentation, reading, local amplification and measurement for medical image in DICOM format can be realized. Application of the method for processing human CT image data demonstrated the method is a convenient and flexible approach for medical image processing. This user-friendly image processing technique could be clinically useful to assist image analysis and diagnosis. Keywords-DICOM; medical image; image processing; local amplification
发展更加灵活、准确的医学图像处理技术和平台是临床诊断和治疗的重要要求。本文提出了一种新的交互式图像处理方法。利用该方法可以实现DICOM格式医学图像的平滑、锐化、直方图处理、伪彩色处理、分割、读取、局部放大和测量。应用该方法处理人体CT图像数据表明,该方法是一种方便、灵活的医学图像处理方法。这种用户友好的图像处理技术可用于临床辅助图像分析和诊断。Keywords-DICOM;医学图像;图像处理;局部放大
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引用次数: 10
Metadata Oriented Software Development Method 面向元数据的软件开发方法
Pub Date : 2009-10-30 DOI: 10.1109/BMEI.2009.5305826
Yiping Jiang, Lianzhong Liu, Wei Lv, Chi-long Zhao
By summarizing the software development experience and the research on the software methodology, the paper presented a metadata oriented software development method. The practice of this method in the real world software development had been discussed. Meanwhile we compared this method with other methods and pointed out that these methods are interrelated and indivisible. These methods should be used together in software development to facilitate the success of the development. Keywords-Software engineering; Development method; Metadata Oriented
本文在总结软件开发经验和软件方法论研究的基础上,提出了一种面向元数据的软件开发方法。讨论了该方法在实际软件开发中的实践。同时将该方法与其他方法进行了比较,指出这些方法是相互联系、不可分割的。这些方法应该在软件开发中一起使用,以促进开发的成功。Keywords-Software工程;开发方法;元数据的
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引用次数: 1
Detect the Different Isoforms Using GeneChip Human Exon 1.0 ST Arrays 使用GeneChip Human Exon 1.0 ST阵列检测不同的异构体
Pub Date : 2009-10-30 DOI: 10.1109/BMEI.2009.5305187
Mi-Chia Ma, Hsiao-Fang Lin, Ying Xu
Alternative splicing is the RNA splicing variation mechanism. The exon isoforms lead to numerous different expressions through the alternative splicing. It’s imperative to find the carcinogenic gene from the massive quantity of genes and understand the expressed isoforms. In this paper, the statistical procedures are applied on the colon cancer sample data of Affymetrix GeneChip Human Exon 1.0 ST Array and the dataset is used as the example of finding isoforms. First, the Wilcoxon sign rank test was applied to choose the suspect carcinogenic genes. About 54,854 suspect genes are selected from original 312,368 genes at 5% significant level. Second, one sample t-test and the factor analysis are used to estimate the tumor and normal isoforms for each suspect carcinogenic gene, respectively. Furthermore, the confirmations are made by comparing the estimated results with Alternative Splicing Database. Finally, the results may be provided to the biologist to make biological confirmations and discover the new isoforms. Keywords-alternative splicing; exon array; colon cancer; isoform
选择性剪接是RNA剪接变异机制。外显子异构体通过选择性剪接导致许多不同的表达。从大量的基因中找到致癌基因并了解其表达的同工型是当务之急。本文将统计程序应用于Affymetrix GeneChip Human Exon 1.0 ST Array的结肠癌样本数据,并以该数据集为例进行同种异构体的发现。首先,采用Wilcoxon符号秩检验选择可疑致癌基因。从原始的312368个基因中,以5%的显著性水平筛选出54854个可疑基因。其次,使用单样本t检验和因子分析分别估计每个可疑致癌基因的肿瘤和正常亚型。并将估计结果与Alternative Splicing Database进行了比较。最后,这些结果可以提供给生物学家进行生物学确认和发现新的异构体。Keywords-alternative拼接;外显子数组;结肠癌;同种型
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引用次数: 0
Extended Gate H+-Ion Sensitive Field Effect Transistor with Signal Interface 带信号接口的扩展栅氢离子敏感场效应晶体管
Pub Date : 2009-10-30 DOI: 10.1109/BMEI.2009.5305321
Chung-Yuan Chen, Hsiu-Li Hsieh, Chia-Hsien Lin, S. Liao, T. Sun, C. Ching, Po-Liang Liu
H + -ion concentration into digital form. This chip, fabricated in a 0.18-um CMOS 1P6M process, operated at a 1.8V supply voltage and normal sampling rate of 6.25MHz. The circuit (without pad) occupied an area of 0.66mm × 0.43mm. The experimental data showed that this structure has a linear pH response about 97 digital counts/pH in the ion concentration range between pH2 and pH12, and the gain errors within the H + -ion concentrations are less than 3%. The minimum detectable pH value can reach as small as ±0.25pH.
H +离子浓度转化为数字形式。该芯片采用0.18 um CMOS 1P6M工艺,工作在1.8V电源电压下,正常采样率为6.25MHz。电路(不含焊盘)的面积为0.66mm × 0.43mm。实验数据表明,该结构在pH2 ~ pH12离子浓度范围内具有97个数字计数/pH左右的线性pH响应,且在H +离子浓度范围内的增益误差小于3%。最小可检测pH值可小至±0.25pH。
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引用次数: 4
Predicting Plant Pol-II Promoter Based on Subsequence Increment of Overlap Content Diversity 基于重叠内容多样性子序列增量的植物Pol-II启动子预测
Pub Date : 2009-10-30 DOI: 10.1109/BMEI.2009.5305749
Yongchun Zuo, Qianzhong Li
Promoter identification is the first and the most important step for understanding gene transcription regulation. In this study, one new information content feature, the subsequence increment of overlapping content diversity (IOCD), is firstly presented to describe the subsequence content of plant poll-Ⅱ promoter. The negative datasets include five different regions of Arabidopsis thaliana complete genomes, Codings, Introns, Intergenics, 5'untranslation regions (UTRs) and 3' untranslation regions (UTRs). The prediction capacity of our algorithm is tested by 10-fold cross validation test based on K- mer IOCD. The results show that the IOCD can describe the promoter sequence content well. Further, based on the interval distances between transcription start site (TSS) and translation initiation site (TIS), the method is applied to search the complete genomes of Arabidopsis thaliana and more than ten thousand probable promoters are founded.
启动子鉴定是了解基因转录调控的第一步,也是最重要的一步。本文首次提出了一种新的信息内容特征——重叠内容多样性子序列增量(IOCD)来描述植物poll-Ⅱ启动子的子序列内容。阴性数据集包括拟南芥全基因组的5个不同区域、编码区、内含子、间基因区、5′非翻译区和3′非翻译区。通过基于K- mer IOCD的10次交叉验证测试,验证了算法的预测能力。结果表明,IOCD能较好地描述启动子序列的内容。进一步,基于转录起始位点(TSS)和翻译起始位点(TIS)之间的间隔距离,将该方法应用于拟南芥全基因组的搜索,发现了1万多个可能的启动子。
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引用次数: 3
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2009 2nd International Conference on Biomedical Engineering and Informatics
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