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2019 IEEE SENSORS最新文献

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Measuring Analyte Desorption using a Surfactant Hydrodynamic Retardation Effect Detector 用表面活性剂水动力延迟效应检测器测量分析物解吸
Pub Date : 2019-10-01 DOI: 10.1109/SENSORS43011.2019.8956856
Afreen Fatima, A. Basu
A common issue in biomicrofluidic systems is that fluidic channels may become contaminated when ampiphilic molecules adsorb to the hydrophobic channel walls. Desorption rates are often measured using optical methods, many of which require a chromophore or a fluorophore label. This paper describes label-free desorption measurements using a drop frequency sensor (DFS), a microfluidic sensor reported recently by our group. The DFS is based on a surfactant retardation effect which measures the drag of surface-active agents on microdroplets generated in a tee junction. We measure desorption curves of Tween, a small molecule surfactant, from the walls of a polydimethylsiloxane channels. Typical desorption times increase with Tween concentration, ranging from 45 to 324 seconds at Tween concentrations between 10 and 1000 ppm. The limit of detection is 10 ppm.
生物微流控系统的一个常见问题是,当两亲分子吸附到疏水通道壁上时,流体通道可能被污染。解吸率通常使用光学方法测量,其中许多方法需要发色团或荧光团标签。本文描述了使用滴频传感器(DFS)的无标签解吸测量,这是我们小组最近报道的一种微流体传感器。DFS是基于表面活性剂的缓阻效应,测量表面活性剂对在三通结中产生的微滴的阻力。我们测量了小分子表面活性剂Tween从聚二甲基硅氧烷通道壁上的解吸曲线。典型的解吸时间随着吐温浓度的增加而增加,吐温浓度在10到1000 ppm之间时,从45到324秒不等。检测限为10ppm。
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引用次数: 0
Sensor System for Open/Closed Eye Detection in Infants During Feeding 婴幼儿喂养过程睁眼/闭眼检测传感器系统
Pub Date : 2019-10-01 DOI: 10.1109/SENSORS43011.2019.8956719
Tonmoy Ghosh, E. Sazonov, P. Chandler-Laney
Rapid weight gain during infancy expands the threat of obesity. Currently, there is a lack of tools to monitor the feeding behavior of infants. This paper presents a sensor system and a method for inspecting satiety cues exhibited by infants during feeding in the form of opening/closing of the eyes. Open eyes and vigorous sucking indicate an alert, actively feeding infant, while eye closing in combination with a slower frequency or lower strength of sucking indicate that an infant is getting full and falling asleep. The monitoring is performed by a sensor system consisting of a feeding bottle instrumented with a camera to monitor facial expression and a pressure sensor to monitor sucking. A method for open eye detection is proposed based on the histograms of oriented gradients features and multi-stage cascade classifier. In a pilot study of 4 infants, a recall value of 82.40% and F1-score of 80.79% was achieved while testing on 914 infant images.
婴儿时期体重的迅速增加增加了肥胖的威胁。目前,缺乏监测婴儿喂养行为的工具。本文介绍了一种检测婴儿在喂养过程中以睁眼/闭眼形式表现的饱腹感信号的传感系统和方法。睁着眼睛和有力的吸吮表明婴儿警觉,积极地喂养,而闭上眼睛并结合较慢的频率或较低的吸吮强度表明婴儿正在吃饱和入睡。监测由一个传感器系统执行,该传感器系统由一个装有摄像头的喂养瓶和一个压力传感器组成,该传感器用于监测面部表情和监测吸吮。提出了一种基于方向梯度特征直方图和多级级联分类器的睁眼检测方法。在4名婴儿的试点研究中,对914张婴儿图像进行测试,记忆率为82.40%,f1得分为80.79%。
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引用次数: 0
Relative Humidity Sensing using PANI/PVA integrated with Feedback Oscillator Circuit 基于反馈振荡器电路的聚苯胺/聚乙烯醇相对湿度传感
Pub Date : 2019-10-01 DOI: 10.1109/SENSORS43011.2019.8956563
M. Abdolrazzaghi, F. Hariri, M. Chu, H. Naguib, M. Daneshmand
In this work, polyaniline polymer is used for relative humidity level sensing mounted on a planar microwave oscillator. This intrinsically conducting polymer becomes lossy with water ingress. The sensing transducer is based on two concentric split-ring resonator that is designed at high frequency of 5 GHz to exploit the sensitivity. The loss of the resonator is compensated with positive feedback loop and the oscillation is controlled with varactor as the phase modifier. Relative humidity levels of ~ 5 % - 65 % is measured linearly using the proposed sensor with a sensitivity of 833 kHz/degree that agrees with commercial sensor.
本文将聚苯胺聚合物用于平面微波振荡器的相对湿度传感。这种本质上导电的聚合物随着水的进入而损耗。该传感传感器基于两个同心分裂环谐振腔,设计在5ghz高频,以发挥灵敏度。用正反馈回路补偿谐振器的损耗,用变容器作为相位调节器控制谐振器的振荡。相对湿度水平~ 5% - 65%是线性测量,使用该传感器的灵敏度为833千赫/度,与商用传感器一致。
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引用次数: 8
High Frequency Gas Detection With an Uncoated CMUT Array by Impedance Resonant Frequency Measurement 无涂层CMUT阵列高频气体检测阻抗谐振频率测量
Pub Date : 2019-10-01 DOI: 10.1109/SENSORS43011.2019.8956767
Luis Iglesias Hernandez, I. Dufour, P. Shanmugam, J. Michaud, D. Alquier, D. Certon
This paper shows for the first time the ability to detect different gases by tracking the impedance of an uncoated silicon nitride capacitive micromachined ultrasonic transducer (CMUT) array at the anti-resonant frequency. The principle of this chemical detection is based on the influence of a physical property of the gas (the mass density) on the resonant properties of the CMUTs. In this paper, we present results for carbon dioxide and hydrogen detection. Potential applications of such sensor include long term gas monitoring or fast response gas sensing for gas leakage detection.
本文首次展示了通过跟踪无涂层氮化硅电容式微机械超声换能器(CMUT)阵列在反谐振频率下的阻抗来检测不同气体的能力。这种化学检测的原理是基于气体的物理性质(质量密度)对cmut谐振特性的影响。在本文中,我们介绍了二氧化碳和氢的检测结果。这种传感器的潜在应用包括长期气体监测或用于气体泄漏检测的快速响应气体传感。
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引用次数: 0
Fast response hydrogel-based plasmonic sensor substrate for the detection of ethanol 用于乙醇检测的快速响应水凝胶等离子体传感器衬底
Pub Date : 2019-10-01 DOI: 10.1109/SENSORS43011.2019.8956577
C. Kroh, R. Wuchrer, Nadja Steinke, Margarita Guenther, G. Gerlach, T. Härtling
The inline monitoring of ethanol concentrations in liquids is a crucial part of process monitoring in breweries and distilleries. Current methods are based on infrared spectroscopy which are bulky and costly making them non-affordable for small and middle-sized companies. To overcome these problems, we present a small, compact and cost-effective sensing method, based on a nanostructured, plasmonically active sensor substrate. The sensor substrate is coated with a microstructured ethanol-sensitive acrylamide-bisacrylamide hydrogel which induces a change of the hydrogel’s refractive index in conjugation with the hydrogel swelling and shrinking. With such an approach, the ethanol concentration in liquids can be determined in a simple optical transmittance setup. In our study, we demonstrate the capability of the sensor principle for the detection of ethanol concentration ranging from 0 to 30 vol%. Furthermore, we determined the response time of the sensor substrate to be less than 10 seconds, which shows an enormous improvement compared to other hydrogel-based sensing methods. Finally, initial results for real sample measurements are presented.
液体中乙醇浓度的在线监测是啤酒厂和酿酒厂过程监测的重要组成部分。目前的方法是基于红外光谱,体积大,成本高,中小型公司负担不起。为了克服这些问题,我们提出了一种基于纳米结构等离子体有源传感器衬底的小型,紧凑且具有成本效益的传感方法。在传感器衬底上涂覆一层微结构的乙醇敏感丙烯酰胺-双丙烯酰胺水凝胶,水凝胶的折射率随水凝胶的膨胀和收缩而变化。利用这种方法,可以在一个简单的光学透射率设置中确定液体中的乙醇浓度。在我们的研究中,我们展示了传感器原理检测乙醇浓度范围从0到30 vol%的能力。此外,我们确定传感器衬底的响应时间小于10秒,与其他基于水凝胶的传感方法相比,这显示出巨大的改进。最后给出了实际样品测量的初步结果。
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引用次数: 0
A Novel Detection of Biomarker Molecule of α-synuclein for Parkinson Disease by Phospholipid Liposome-Immobilized Cantilever Biosensor Using Real-Time Quaking-Induced Conversion Method 基于实时振动诱导转换方法的磷脂脂质体-固定化悬臂式生物传感器检测帕金森病α-突触核蛋白生物标志物分子
Pub Date : 2019-10-01 DOI: 10.1109/SENSORS43011.2019.8956615
R. Kobayashi, M. Noda, M. Sawamura, H. Yamakado, Masayuki Sohgawa
We newly applied real-time quaking-induced conversion (RT-QuIC) method for phospholipid liposome-immobilized cantilever sensor in order to obtain a trace amount of chronological behavior of α−synuclein (aSyn) as causative agent for Parkinson Disease. Our goal is to detect aggregated, not a monomeric, forms of aSyn in its initial stage, as it is most toxic in patient’s cerebrospinal fluid (CSF). Especially, by introducing similar processes of the RT-QuIC on a microscale cantilever surface, pM order aSyn fibril was detected, further indicating several hundreds of fM detection in the cantilever biosensor system that is fluorescent label-free technique.
为了获得作为帕金森病致病因子的α -突触核蛋白(aSyn)的痕量时序行为,我们采用实时振动诱导转换(RT-QuIC)方法对磷脂脂质体-固定化悬臂传感器进行了研究。我们的目标是在初始阶段检测聚合而非单体形式的aSyn,因为它在患者脑脊液(CSF)中毒性最大。特别是,通过在微尺度悬臂表面上引入RT-QuIC的类似过程,检测到pM阶的aSyn纤维,进一步表明在悬臂生物传感器系统中可以检测到数百种fM,这是一种无荧光标记技术。
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引用次数: 4
Sample Tube pH Monitoring via Passive Powering and Communication 通过无源供电和通信监测样管pH值
Pub Date : 2019-10-01 DOI: 10.1109/SENSORS43011.2019.8956639
Paul Marsh, Yi Zhuang, Zhenghan Xu, Lauren Heine, H. Cao
This paper presents the application of a simple, inductively-coupled potentiometric pH measurement system into the cap of standard laboratory sample tubes, thus enabling continuous, wireless monitoring of a bevy of samples. The system is powered by a compact Class E amplifier using inductive coupling via a designed resonance frequency of 1 MHz. Signals are transmitted back via load modulation at frequencies a fraction of the power carrier frequency, thus allowing for extraction of the signal frequency. Results are demonstrated which clearly show that modulation frequency tracks closely with open circuit potential, and the system as a whole features good sensitivity and linearity. This system holds promise for a host of applications.
本文介绍了将一种简单的电感耦合电位pH测量系统应用于标准实验室样管的瓶盖上,从而实现对一堆样品的连续无线监测。该系统由一个紧凑的E类放大器供电,采用电感耦合,通过设计的谐振频率为1 MHz。信号通过负载调制以功率载波频率的一小部分频率传输回来,从而允许提取信号频率。结果表明,该系统的调制频率与开路电位密切相关,具有良好的灵敏度和线性度。这个系统为许多应用程序带来了希望。
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引用次数: 2
Novel Resonance-Like Impedance Spectroscopy for Life Science Applications 生命科学应用的新型类共振阻抗谱
Pub Date : 2019-10-01 DOI: 10.1109/SENSORS43011.2019.8956812
Giancarlo Ayala-Charca, S. Magierowski, E. Ghafar-Zadeh
This paper presents a novel real-time resonance-like impedance spectroscopy method using ITO electrodes. These electrodes can exhibit N-Shape Nonlinear Negative Differential Resistance (NDR) under specific conditions. In these conditions, the impedance of the electrode becomes pure capacitive, resulting in a resonance-shape spectrum. The resonance frequency is related to electrochemical changes at the interface between electrode and sample. We validated this method using microfabricated ITO electrodes exposed to two chemical solutions, including DMEM culture medium and 0.9% NaCl Solution. Based on these results, the proposed method can offer great advantages of rapid impedance spectroscopy for high throughput screening of chemical and biological materials suitable for a variety of life sciences applications.
本文提出了一种利用ITO电极的实时类共振阻抗谱方法。这些电极在特定条件下可以表现出n形非线性负差分电阻(NDR)。在这些条件下,电极的阻抗变成纯电容性,导致共振形状的频谱。谐振频率与电极与样品界面处的电化学变化有关。我们将微型ITO电极暴露在两种化学溶液中,包括DMEM培养基和0.9% NaCl溶液中,验证了该方法。基于这些结果,该方法具有快速阻抗谱高通量筛选适合多种生命科学应用的化学和生物材料的巨大优势。
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引用次数: 1
Fabrication of a Bioimpedance Sensor via Inkjet Printing and Selective Metallization 利用喷墨打印和选择性金属化技术制备生物阻抗传感器
Pub Date : 2019-10-01 DOI: 10.1109/SENSORS43011.2019.8956645
R. Bernasconi, D. Meroni, A. Aliverti, L. Magagnin
The significant incidence of cancer on public health in the modern industrialized world is pushing the research on novel therapeutic techniques and diagnosis tools. The latter, in particular, are of vital importance, since in many cases a prompt cancer diagnosis can significantly decrease patient’s mortality. Bioimpedance tissue analysis, in particular, is gaining attention as a promising methodology to identify tumor. Manufacturing technologies for bioimpedance probes are however still not completely adapt for cost effective mass production. In this context, the present work aims at producing a costless bioimpedance sensor by employing inkjet printing and electrolytic metal deposition. The probe manufactured in this way is successfully employed for bioimpedance testing of three animal tissues, demonstrating ability to successfully distinguish between them.
在现代工业化国家,癌症对公共卫生的重大影响正在推动新的治疗技术和诊断工具的研究。后者尤其至关重要,因为在许多情况下,及时的癌症诊断可以显著降低患者的死亡率。特别是生物阻抗组织分析,作为一种很有前途的肿瘤识别方法而受到关注。然而,生物阻抗探针的制造技术仍然不能完全适应具有成本效益的大规模生产。在这种情况下,目前的工作旨在通过喷墨打印和电解金属沉积生产一种无成本的生物阻抗传感器。用这种方法制造的探针成功地用于三种动物组织的生物阻抗测试,证明了成功区分它们的能力。
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引用次数: 3
Magnetoresistive Point Field Detector-based Current Sensing for Power Electronics with Bandwidth Extension 基于磁阻点场探测器的带宽扩展电力电子电流传感
Pub Date : 2019-10-01 DOI: 10.1109/SENSORS43011.2019.8956625
Muhammad H. Alvi, Minhao Sheng, R. Lorenz, T. Jahns
Giant Magnetoresistive (GMR) point field detectors (PFDs) have been integrated into power electronic converters for high-bandwidth galvanically-isolated current sensing in conductors that are especially designed for magnetic field shaping. In this work, a methodology is introduced to sense currents in standard conductors with very high bandwidth by detecting the magnetic field as a vector in multi-dimensional space. Tools are developed to identify the field components in directions that do not have frequency-dependent changes arising from skin effect in the conductors. The importance of orienting the PFD in a particular point is identified as critical to the flat frequency response of current sensing. In this paper, bandwidth extension for busbar current sensing is experimentally verified by sensing the magnetic field using a rotated 1-D GMR as well as by computing the same magnetic field vector from orthogonal X and Y outputs of a 2-D GMR PFD. Current sensing bandwidth extension using the multi-dimensionality of the magnetic field leads to compact, low-cost current sensing without complicated conductor designs.
巨磁阻(GMR)点场探测器(pfd)已被集成到电力电子变换器中,用于高带宽电隔离电流传感,特别是为磁场成形而设计的导体。在这项工作中,介绍了一种方法,通过在多维空间中检测作为矢量的磁场来检测具有非常高带宽的标准导体中的电流。开发了工具来识别方向上的场分量,这些方向没有由导体中的趋肤效应引起的频率相关变化。将PFD定向在特定点上的重要性被认为是电流传感平坦频率响应的关键。本文通过实验验证了母线电流传感的带宽扩展,通过使用旋转的1-D GMR以及通过从2-D GMR PFD的正交X和Y输出计算相同的磁场矢量来传感磁场。利用磁场的多维度扩展电流传感带宽,可以实现紧凑、低成本的电流传感,而无需复杂的导体设计。
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引用次数: 1
期刊
2019 IEEE SENSORS
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