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Non-fullerene acceptor based photoelectric material for retinal prosthesis 基于非富勒烯受体的视网膜假体光电材料
IF 3.6 Q2 NANOSCIENCE & NANOTECHNOLOGY Pub Date : 2023-09-28 DOI: 10.1186/s40486-023-00177-8
Hyunsun Song, Hyeonhee Roh, Jae Young Kim, Byung Chul Lee, Bright Walker, Maesoon Im

Microelectronic retinal implants can restore a useful level of artificial vision in photoreceptor-damaged retina. Previously commercialized retinal prostheses require transocular connection lines to an external power supply and/or for data transmission, which are unwieldy and may cause unwanted side effects, such as infections. A recently reported wireless device used a rigid silicon substrate. However, it had the potential for a long-term mechanical mismatch with soft retinal tissue. In this work, we used organic photovoltaic materials which can be fabricated on flexible substrates as well as be operated without any physical connection to the external world. The present study employed PCE10 as an active layer for retinal prosthetic application for the first time. Compared to previously studied organic photovoltaic materials used in retinal prosthesis research (such as P3HT), our PCE10 devices showed higher efficiency, providing a huge advantage in this field. When the PCE10 was blended with other non-fullerene acceptors achieving a ternary organic photovoltaic layer (PCE10:ITIC:Y6 blend), it showed lower reduction of photocurrent under same irradiation frequency condition. The fabrication method for our organic photovoltaic device was simple and easy to control its thickness. The fabricated devices showed adequate photocurrent to stimulate the retinal neurons with a smaller reduction in generated photocurrent during repeating stimuli compared to P3HT or PCE10 alone.Author names: Please confirm if the author names are presented accurately and in the correct sequence (given name, middle name/initial, family name). Author: Given name [Jae Young] Last name [Kim]. Author: Given name [Byung Chul] Last name [Lee].Yes, they are correct.

微电子视网膜植入物可以在受光感受器损伤的视网膜上恢复有用的人工视力。以前商业化的视网膜假体需要经眼连接到外部电源和/或数据传输,这是笨重的,可能会导致不必要的副作用,如感染。最近报道了一种使用刚性硅衬底的无线设备。然而,它有可能与软视网膜组织长期机械不匹配。在这项工作中,我们使用了有机光伏材料,它可以在柔性衬底上制造,并且可以在没有任何物理连接的情况下与外部世界进行操作。本研究首次采用PCE10作为视网膜假体应用的活性层。与之前研究的用于视网膜假体研究的有机光伏材料(如P3HT)相比,我们的PCE10器件具有更高的效率,在该领域具有巨大的优势。当PCE10与其他非富勒烯受体共混形成三元有机光伏层(PCE10:ITIC:Y6共混物)时,在相同辐照频率条件下,其光电流降低幅度较小。本发明的有机光伏器件制作方法简单,厚度易于控制。与单独的P3HT或PCE10相比,制造的装置显示出足够的光电流来刺激视网膜神经元,并且在重复刺激期间产生的光电流减少较少。作者姓名:请确认作者姓名是否准确且顺序正确(名,中间名/首字母,姓)。作者:名[Jae Young]姓[Kim]。作者:名[秉哲]姓[李]。是的,他们是正确的。
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引用次数: 0
Investigation of LIG-based pressure sensors with various silicon-based elastomeric encapsulation layers 不同硅基弹性体封装层的硅基压力传感器研究
IF 3.6 Q2 NANOSCIENCE & NANOTECHNOLOGY Pub Date : 2023-09-27 DOI: 10.1186/s40486-023-00176-9
Yoo-Kyum Shin, Ki-Hoon Kim, Min-Ho Seo

Laser-induced graphene (LIG) has attracted significant interest in the field of pressure sensors owing to the high sensitivity associated with its inherent three-dimensional porous structure. However, the brittleness of fabricated LIG poses a critical challenge in terms of durability. To address this issue, current research on LIG-based pressure sensors has focused on the utilization of Si-elastomer encapsulation layers. Despite the importance of the mechanical properties of Si elastomers for the performance of physical sensors, few studies have been conducted on the characterization of pressure sensors based on the encapsulation layer. In this study, we investigated the electromechanical characteristics of LIG-based pressure sensors encapsulated in various Si-based elastomers. For an unbiased evaluation, we first introduce a simple and reliable fabrication process for LIG-based pressure sensors with different Si-elastomer encapsulation layers. Subsequently, the electromechanical responses of the sensors were characterized using an automated pressure machine, demonstrating that sensors with encapsulation layers with a lower Young’s modulus exhibited increased resistance changes and extended response times. Finally, an in-depth exploration of the environmental stability of the pressure sensors was conducted for various encapsulation materials, ultimately confirming negligible performance variations based on the encapsulation materials.

激光诱导石墨烯(LIG)由于其固有的三维多孔结构具有高灵敏度,在压力传感器领域引起了极大的兴趣。然而,制造LIG的脆性对耐久性提出了严峻的挑战。为了解决这一问题,目前基于li的压力传感器的研究主要集中在硅弹性体封装层的利用上。尽管硅弹性体的力学性能对物理传感器的性能非常重要,但基于封装层的压力传感器的表征研究却很少。在这项研究中,我们研究了封装在各种硅基弹性体中的硅基压力传感器的机电特性。为了进行公正的评估,我们首先介绍了具有不同硅弹性体封装层的基于lige的压力传感器的简单可靠的制造工艺。随后,使用自动化压力机对传感器的机电响应进行了表征,证明具有较低杨氏模量的封装层的传感器具有更大的电阻变化和更长的响应时间。最后,对各种封装材料对压力传感器的环境稳定性进行了深入的探索,最终确定了基于封装材料的性能变化可以忽略不计。
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引用次数: 0
Overcoming delamination in two-photon lithography for improving fabrication of 3D microstructures 克服双光子光刻中分层现象,改善三维微结构的制造
IF 3.6 Q2 NANOSCIENCE & NANOTECHNOLOGY Pub Date : 2023-09-22 DOI: 10.1186/s40486-023-00173-y
Cheol Woo Ha

Two-photon lithography has emerged as a highly effective method for fabricating intricate three-dimensional (3D) microstructures. It enables the rapid fabrication of 3D microstructures, unlike conventional two-dimensional nanopatterning. Researchers have extensively investigated two-photon polymerization (TPP) for the fabrication of diverse 3D micro/nanodevices with high resolution. TPP can be applied in cell cultures, metamaterials, optical materials, electrical devices, and fluidic devices, to name a few. In this study, we investigate the applications and innovative research pertaining to TPP, which is an effective fabrication technique with significant advancement in various fields. In particular, we attempt to determine the reasons that cause the detachment or delamination of 3D microstructures during the development process and propose some solutions. A step-by-step fabrication process for a glass substrate, from photoresist deposition to laser scanning and the dissolution of the uncured photoresist, is presented. Defects such as pattern delamination are discussed, with emphasis on the cell scaffold structure and microlens array. Understanding and addressing these defects are vital to the success of 3D microstructure fabrication via TPP.

双光子光刻技术已经成为一种制造复杂三维微结构的高效方法。它使3D微结构的快速制造成为可能,不像传统的二维纳米图形。研究人员广泛地研究了双光子聚合(TPP)用于制造各种高分辨率的三维微/纳米器件。TPP可以应用于细胞培养、超材料、光学材料、电子设备和流体设备等。在本研究中,我们探讨了与TPP相关的应用和创新研究,这是一种有效的制造技术,在各个领域都有显著的进步。特别是,我们试图确定在开发过程中导致三维微结构脱离或分层的原因,并提出一些解决方案。介绍了从光刻胶沉积到激光扫描和未固化光刻胶溶解的玻璃基板的一步一步制造过程。讨论了诸如图案分层等缺陷,重点讨论了细胞支架结构和微透镜阵列。了解和解决这些缺陷对于通过TPP成功制造3D微结构至关重要。
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引用次数: 0
Sweat-permeable electronic skin with a pattern of eyes for body temperature monitoring 带有眼睛图案的防汗电子皮肤,用于体温监测
IF 3.6 Q2 NANOSCIENCE & NANOTECHNOLOGY Pub Date : 2023-09-15 DOI: 10.1186/s40486-023-00170-1
Jeong Hyeon Kim, Daniel J. Joe, Han Eol Lee

Human-machine interface has been considered as a prominent technology for numerous smart applications due to their direct communication between humans and machines. In particular, wearable electronic skins with a free form factor have received a lot of attention due to their excellent adherence to rough and wrinkled surfaces such as human skin and internal organs. However, most of the e-skins reported to date have some disadvantages in terms of mechanical instability and accumulation of by-products at the interface between the human skin and the device. Here, we report a mechanically stable e-skin via a newly designed pattern named the “eyes.” The ingeniously designed pattern of the eyes allowed mechanical stress and strain to be dissipated more effectively than other previously reported patterns. E-skin permeability of by-product was experimentally confirmed through sweat removal tests, showing superior sweat permeability compared to conventional e-skins. Finally, the real-time monitoring of the body temperature was carried out using our resistive-type thermometer in the e-skin.

人机界面由于其在人与机器之间的直接通信而被认为是许多智能应用的重要技术。特别是具有自由外形因素的可穿戴电子皮肤,由于其对人体皮肤和内部器官等粗糙和皱褶表面的良好粘附性而受到广泛关注。然而,迄今为止报道的大多数电子皮肤在人体皮肤和设备之间的界面上的机械不稳定性和副产品积累方面存在一些缺点。在这里,我们报告了一个机械稳定的电子皮肤通过一个新设计的模式命名为“眼睛”。眼睛的巧妙设计模式允许机械应力和应变比其他先前报道的模式更有效地消散。通过排汗实验证实了副产物电子皮肤的透湿性,与传统电子皮肤相比,具有更好的透湿性。最后,使用我们的电阻式体温计在电子皮肤中进行体温的实时监测。
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引用次数: 0
Fabrication and evaluation of a flexible temperature sensor array using multi-layer ceramic capacitors for spatial temperature mapping 利用多层陶瓷电容器进行空间温度映射的柔性温度传感器阵列的制造与评价
IF 3.6 Q2 NANOSCIENCE & NANOTECHNOLOGY Pub Date : 2023-09-13 DOI: 10.1186/s40486-023-00172-z
Ji-Sung Yoon, Kwang-Seok Yun

This paper presents the development of a flexible temperature sensor array using multi-layer ceramic capacitors. By integrating the capacitors into a 5 × 5 array on a polydimethylsiloxane (PDMS) substrate, we exploit the principle of changing dielectric constant with temperature, which results in a change in capacitance. Our sensor array demonstrates a consistent decrease in capacitance with increasing temperature, with a sensitivity ranging from 1.42 to 1.62 pF/°C. This sensitivity range is maintained even when measurements are taken using a capacitance-to-voltage conversion circuit, with a sensitivity of 1.1 to 1.5 mV/°C. The repeatability and hysteresis of the sensors were also investigated, with the latter revealing a maximum error of 12.7%. Our findings provide valuable insights for the development of efficient, flexible, and reliable temperature sensor arrays using ceramic capacitors.

本文介绍了一种采用多层陶瓷电容器的柔性温度传感器阵列的研制。通过在聚二甲基硅氧烷(PDMS)衬底上将电容器集成成5 × 5阵列,我们利用介电常数随温度变化的原理,从而导致电容的变化。我们的传感器阵列显示电容随温度升高而持续下降,灵敏度范围为1.42至1.62 pF/°C。即使使用灵敏度为1.1至1.5 mV/°C的电容-电压转换电路进行测量,也能保持该灵敏度范围。对传感器的可重复性和滞后性进行了研究,后者的最大误差为12.7%。我们的发现为使用陶瓷电容器开发高效、灵活和可靠的温度传感器阵列提供了有价值的见解。
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引用次数: 0
Improved recovery of NO2 sensors using heterojunctions between transition metal dichalcogenides and ZnO nanoparticles 利用过渡金属二硫化物和ZnO纳米颗粒之间的异质结提高NO2传感器的回收率
IF 3.6 Q2 NANOSCIENCE & NANOTECHNOLOGY Pub Date : 2023-09-11 DOI: 10.1186/s40486-023-00171-0
Leilei Wang, Jungwook Choi

The stable recovery of gas sensors is an important indicator for evaluating their performance. Hitherto, the use of external light sources and/or an increase in the operating temperature has been effective in improving the recovery rate of gas sensors. Herein, heterojunctions were formed between the two-dimensional transition metal dichalcogenide nanosheets and zero-dimensional ZnO nanoparticles to improve the recovery rate of a NO2 sensor. Scanning electron microscopy and Raman spectroscopy suggested a successful deposition of ZnO nanoparticles onto the MoS2 and WSe2 nanosheets. The sensing response to 10 ppm NO2 gas at 100 °C indicated that the heterojunction formed by ZnO and MoS2 or WSe2 successfully improved the recovery rate of the sensor by 11.87% and 19.44%, respectively, whereas the sensitivity remained constant. The proposed approach contributes to improving the performance of gas sensors.

气体传感器的稳定回收率是评价其性能的重要指标。迄今为止,使用外部光源和/或提高工作温度在提高气体传感器的回收率方面是有效的。通过在二维过渡金属二硫化物纳米片和零维ZnO纳米片之间形成异质结,提高了NO2传感器的回收率。扫描电镜和拉曼光谱显示ZnO纳米粒子成功沉积在MoS2和WSe2纳米片上。在100℃下,对10ppm NO2气体的传感响应表明,ZnO与MoS2或WSe2形成的异质结成功地将传感器的回收率分别提高了11.87%和19.44%,而灵敏度保持不变。该方法有助于提高气体传感器的性能。
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引用次数: 0
Hydrophobic surface for direct PEGDA micro-pattern fabrication 用于直接PEGDA微图案制作的疏水表面
IF 3.6 Q2 NANOSCIENCE & NANOTECHNOLOGY Pub Date : 2023-06-07 DOI: 10.1186/s40486-023-00169-8
Anna Danielak, Juhee Ko, Aminul Islam, David Bue Pedersen, Jungchul Lee

Photopolymerization of hydrogels films has gained interest in many biomedical and industrial fields. Hydrogel micro-patterns fabricated directly on a device are used as filtering barriers, however, due to weak mechanical properties, these parts require a stable support but deposition of hydrogel in non-polymerized state brings a risk of sinking inside the structure. These limitations can be overcome by applying a hydrophobic surface. This paper presents a novel two-step method, in which a hydrophobic surface was designed and manufactured using mask-projection vat photopolymerization additive manufacturing (VPP). Afterwards, PEGDA-based hydrogel photopolymers were deposited on the surface and a micro-scale patterns were cured. The parts were subjected to water immersion and heating in order to evaluate the swelling and shrinking behaviour of hydrogel. The parts remained stable on the substrate and maintained the properties and the results revealed the shape retention over 97%. This work shows that VPP can be applied in the manufacturing of hydrophobic surfaces for hydrogel photopolymer deposition and curing without sacrificing critical properties.

Graphical Abstract

水凝胶膜的光聚合已在许多生物医学和工业领域引起了人们的兴趣。直接在器件上制备的水凝胶微图案被用作过滤屏障,但由于其力学性能较弱,这些部件需要稳定的支撑,而非聚合状态下的水凝胶沉积会带来在结构内部下沉的风险。这些限制可以通过应用疏水表面来克服。本文提出了一种新的两步法,利用掩模投影缸光聚合增材制造技术(VPP)设计和制造疏水表面。然后,在表面沉积聚乙二醇基水凝胶光聚合物并固化微尺度图案。为了评估水凝胶的膨胀和收缩行为,对零件进行了水浸泡和加热。零件在基体上保持稳定,保持了性能,形状保持率达97%以上。这项工作表明,VPP可以应用于水凝胶光聚合物沉积和固化的疏水表面的制造,而不牺牲关键性能。图形抽象
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引用次数: 0
Advancements in visible-light-driven double perovskite nanoparticles for photodegradation 光降解用可见光驱动双钙钛矿纳米颗粒的研究进展
IF 3.6 Q2 NANOSCIENCE & NANOTECHNOLOGY Pub Date : 2023-05-22 DOI: 10.1186/s40486-023-00168-9
Runia Jana, P. Mary Rajaitha, Sugato Hajra, Hoe Joon Kim

Perovskites are of significant interest in the field of photocatalysis. To date, many perovskite nanostructures have been developed, and their applications in photocatalysis have been studied. There has been considerable improvement in the research on metal doping in the perovskite structure to improve their optical and structural properties. This mini-review examines the recent progress in the synthesis of lead-free double perovskite nanoparticles and their application in visible-light photocatalysis. Lead-free perovskites are emerging as an eco-friendly solution in energy, electrochemistry, and sensing. Double perovskites are known for their flexible structural, optical, and morphological properties due to their lattice framework having a general form AAʹBBʹO6. They are more useful for hydrogen evolution due to their higher conduction band potential than simple perovskites. Here, we summarize the current progress and provide insights for the future development of double perovskites toward efficient photodegradation.

钙钛矿在光催化领域具有重要的研究价值。迄今为止,已经开发了许多钙钛矿纳米结构,并对其在光催化中的应用进行了研究。在钙钛矿结构中掺杂金属以改善其光学和结构性能的研究已经取得了长足的进步。本文综述了近年来无铅双钙钛矿纳米颗粒的合成及其在可见光催化中的应用。无铅钙钛矿正在成为能源、电化学和传感领域的环保解决方案。双钙钛矿以其灵活的结构,光学和形态特性而闻名,因为它们的晶格框架具有一般形式AA ' BB ' O6。由于它们比简单的钙钛矿具有更高的导带电位,因此对析氢更有用。在此,我们总结了目前的研究进展,并对双钙钛矿在高效光降解方面的未来发展提出了见解。
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引用次数: 0
Stimuli-responsive polymer-based bioinspired soft robots 刺激反应聚合物仿生软机器人
IF 3.6 Q2 NANOSCIENCE & NANOTECHNOLOGY Pub Date : 2023-05-08 DOI: 10.1186/s40486-023-00167-w
Swati Panda, Sugato Hajra, P. Mary Rajaitha, Hoe Joon Kim

Soft robotics enables various applications in certain environments where conventional rigid robotics cannot deliver the same performance due to their form factor and stiffness. Animals use their soft external organs to carry out activities in response to challenging natural environments efficiently. The objective of soft robots is to provide biologically inspired abilities and enable adaptable and flexible interactions with complex objects and surroundings. Recent advances in stimuli-responsive soft robot technology have heavily used polymer-based multifunctional materials. Soft robots with incredibly sophisticated multi-mechanical, electrical, or optical capabilities have demonstrated the ability to modify their shape intelligently in response to external stimuli, such as light, electricity, thermal gradient, and magnetic fields. This short review covers recent advances in scientific techniques for incorporating multifunctional polymeric materials into stimuli-responsive bioinspired soft robots and their applications. We also discuss how biological inspiration and environmental effects can provide a viable viewpoint for bioinspired design in the innovative field of soft robotics. Lastly, we highlight the future outlooks and prospects for soft, stimuli-responsive, bio-inspired robots.

软机器人能够在某些环境中实现各种应用,在这些环境中,传统的刚性机器人由于其形状因素和刚度而无法提供相同的性能。动物利用柔软的外部器官进行活动,有效地应对具有挑战性的自然环境。软体机器人的目标是提供生物学启发的能力,并使其能够与复杂的物体和环境进行适应性和灵活的交互。近年来,基于聚合物的多功能材料在刺激响应软机器人技术中的应用越来越广泛。具有令人难以置信的复杂的多机械、电气或光学功能的软机器人已经证明了能够根据外部刺激(如光、电、热梯度和磁场)智能地改变其形状的能力。这篇简短的综述涵盖了将多功能聚合物材料结合到刺激响应型生物仿生软机器人及其应用的科学技术的最新进展。我们还讨论了生物灵感和环境效应如何为软机器人创新领域的生物灵感设计提供可行的观点。最后,我们强调了软的、刺激响应的、仿生机器人的未来展望和前景。
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引用次数: 4
3D printing fabrication process for fine control of microneedle shape 3D打印制造工艺对微针形状进行精细控制
IF 3.6 Q2 NANOSCIENCE & NANOTECHNOLOGY Pub Date : 2023-01-02 DOI: 10.1186/s40486-022-00165-4
Jinwoong Jeong, Jaeu Park, Sanghoon Lee

Microneedle electrode (ME) is used to monitor bioelectrical signals by penetrating via the skin, and it compensates for a limitation of surface electrodes. However, existing fabrication of ME have limited in controlling the shape of microneedles, which is directly relevant to the performance and durability of microneedles as an electrode. In this study, a novel method using 3D printing is developed to control needle bevel angles. By controlling the angle of printing direction, needle bevel angles are changed. Various angles of printing direction (0–90°) are investigated to fabricate moldings, and those moldings are used for microneedle fabrications using biocompatible polyimide (PI). The height implementation rate and aspect ratio are also investigated to optimize PI microneedles. The penetration test of the fabricated microneedles is conducted in porcine skin. The PI microneedle of 1000 μm fabricated by the printing angle of 40° showed the bevel angle of 54.5°, which can penetrate the porcine skin. The result demonstrates that this suggested fabrication can be applied using various polymeric materials to optimize microneedle shape.

微针电极(ME)通过穿透皮肤来监测生物电信号,它弥补了表面电极的局限性。然而,现有的微电极制造技术在控制微针的形状方面存在局限性,这直接关系到微针作为电极的性能和耐久性。在本研究中,开发了一种利用3D打印技术控制针头斜角的新方法。通过控制印刷方向的角度,可以改变针的斜角。研究了不同角度的打印方向(0-90°)来制造模具,这些模具用于使用生物相容性聚酰亚胺(PI)制造微针。为了优化PI微针,还研究了其高度实现率和纵横比。在猪皮中进行了微针的刺入试验。以40°的打印角度制备的1000 μm PI微针的斜角为54.5°,可以穿透猪皮。结果表明,这种方法可以应用于各种聚合物材料来优化微针的形状。
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引用次数: 1
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