Aim: The aim of the study was to examine the relationship between noise exposure and the incidence of arterial hypertension as well as the relationship of noise annoyance and noise sensitivity with hypertension. Methods: A cross-sectional questionnaire survey was performed on 911 adult residents of Niš, Serbia, of whom 388 were men (42.6%) and 523 women (57.4%). The criterium for the diagnosis of arterial hypertension was that it was diagnosed by a physician. Based on measurement results of noise, residents, streets were marked as noisy [daily equivalent noise level (Leq) ≥ 55 dB (A) and night Leq ≥ 45 dB (A)] and as quiet [daily equivalent noise level (Leq) ≤ 55 dB (A) and night Leq ≤ 45 dB (A)]. The numerical and verbal noise annoyance scales were used to assess the degree of noise annoyance, while noise sensitivity was measured with the Weinstein's Noise Sensitivity Scale. Results: Arterial hypertension was statistically significantly more frequent in residents in the noisy area compared to residents in the quiet area. After the inclusion of independent variable factors in the logistic regression models, no significant diference was found (p = 0.66, OR = 1.11; 95% CI: 0.69-1.78). A correlation analysis between noise annoyance wich was measured by verbal and numeric scales and arterial hypertension showed a highly significant positive relation. The same case was between the relationship between subjective sensitivity and arterial hipertension. Conclusion: The introduction of the limit for the community noise level that corresponds to the requirements of highly sensitive persons is a significant measure in preventing the harmful effects of noise on the exposed population.
目的:探讨噪声暴露与动脉高血压的关系，以及噪声烦扰和噪声敏感与高血压的关系。方法:采用横断面问卷调查方法对塞尔维亚尼乌斯市911名成年居民进行调查，其中男性388人(42.6%)，女性523人(57.4%)。动脉高血压的诊断标准是由医生诊断。根据噪声测量结果，将居民、街道标记为嘈杂[日等效噪声级(Leq)≥55 dB (A)，夜间Leq≥45 dB (A)]和安静[日等效噪声级(Leq)≤55 dB (A)，夜间Leq≤45 dB (A)]。使用数字和语言噪声烦恼量表来评估噪声烦恼的程度，而使用温斯坦噪声敏感性量表来测量噪声敏感性。结果:与安静区居民相比，嘈杂区居民动脉高血压发病率有统计学意义。在logistic回归模型中纳入自变量因素后，差异无统计学意义(p = 0.66, OR = 1.11;95% ci: 0.69-1.78)。用语言和数字量表测量的噪声烦恼与动脉高血压呈极显著正相关。主观敏感性与动脉高血压之间的关系也同样如此。结论:引入符合高敏感人群要求的社区噪声限值是预防噪声对暴露人群有害影响的重要措施。
{"title":"The relationship between community noise and arterial hypertension in the population of the city of Niš","authors":"L. Stošić, D. Stojanovic, K. Lazarević","doi":"10.5937/afmnai39-34187","DOIUrl":"https://doi.org/10.5937/afmnai39-34187","url":null,"abstract":"Aim: The aim of the study was to examine the relationship between noise exposure and the incidence of arterial hypertension as well as the relationship of noise annoyance and noise sensitivity with hypertension. Methods: A cross-sectional questionnaire survey was performed on 911 adult residents of Niš, Serbia, of whom 388 were men (42.6%) and 523 women (57.4%). The criterium for the diagnosis of arterial hypertension was that it was diagnosed by a physician. Based on measurement results of noise, residents, streets were marked as noisy [daily equivalent noise level (Leq) ≥ 55 dB (A) and night Leq ≥ 45 dB (A)] and as quiet [daily equivalent noise level (Leq) ≤ 55 dB (A) and night Leq ≤ 45 dB (A)]. The numerical and verbal noise annoyance scales were used to assess the degree of noise annoyance, while noise sensitivity was measured with the Weinstein's Noise Sensitivity Scale. Results: Arterial hypertension was statistically significantly more frequent in residents in the noisy area compared to residents in the quiet area. After the inclusion of independent variable factors in the logistic regression models, no significant diference was found (p = 0.66, OR = 1.11; 95% CI: 0.69-1.78). A correlation analysis between noise annoyance wich was measured by verbal and numeric scales and arterial hypertension showed a highly significant positive relation. The same case was between the relationship between subjective sensitivity and arterial hipertension. Conclusion: The introduction of the limit for the community noise level that corresponds to the requirements of highly sensitive persons is a significant measure in preventing the harmful effects of noise on the exposed population.","PeriodicalId":7132,"journal":{"name":"Acta Facultatis Medicae Naissensis","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71195460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Sabzi, Aghigh Heydari, R. Moghaddam, M. Rouzbahani, Atefeh Asadmobini
Aluminum phosphide, known as "rice tablet" (RT), is a common cause of suicide in adult women in Iran, with a high rate of lethal outcome. We report a patient with RT toxicity, with a complex syndrome of hepatic failure, renal failure, Brugada electrocardiography (ECG) patterns, and pleuropericardial effusion. The patient received conventional management with fluid therapy, gastric washing, activated charcoal followed by intra-aortic balloon pump insertion, inotropic drugs support, and mechanical ventilation. The unique features of our case are related to a combination of multiorgan failure with Brugada atypical ECG patterns and pleuropericardial effusion. Among the aforementioned complications, pleuropericardial effusion, ascites, and Brugada syndrome are exceedingly rare events. The patient was treated with high-dose inotropic drugs and intra-aortic balloon pump insertion. Despite tremendous management of metabolic acidosis, all efforts failed, and the patient died with sudden cardiac arrest.
{"title":"A complex rare presentation of rice tablet poisoning: A case report","authors":"F. Sabzi, Aghigh Heydari, R. Moghaddam, M. Rouzbahani, Atefeh Asadmobini","doi":"10.5937/afmnai38-29018","DOIUrl":"https://doi.org/10.5937/afmnai38-29018","url":null,"abstract":"Aluminum phosphide, known as \"rice tablet\" (RT), is a common cause of suicide in adult women in Iran, with a high rate of lethal outcome. We report a patient with RT toxicity, with a complex syndrome of hepatic failure, renal failure, Brugada electrocardiography (ECG) patterns, and pleuropericardial effusion. The patient received conventional management with fluid therapy, gastric washing, activated charcoal followed by intra-aortic balloon pump insertion, inotropic drugs support, and mechanical ventilation. The unique features of our case are related to a combination of multiorgan failure with Brugada atypical ECG patterns and pleuropericardial effusion. Among the aforementioned complications, pleuropericardial effusion, ascites, and Brugada syndrome are exceedingly rare events. The patient was treated with high-dose inotropic drugs and intra-aortic balloon pump insertion. Despite tremendous management of metabolic acidosis, all efforts failed, and the patient died with sudden cardiac arrest.","PeriodicalId":7132,"journal":{"name":"Acta Facultatis Medicae Naissensis","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71194968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Bubanj, Stevan Đorđević, S. Milenkovic, R. Stanković, Mikica Vidojević, Milan Đokić
The aim of the research was to contribute to better understanding of the correlation between postural disorders and muscle power in primary school children. The sample of respondents consisted of 1,120 children, aged 7 to 12 years (549 boys and 571 girls) from the territory of the municipality of Knjaževac. In the assessment of the spinal column status, the device "Spinal Mouse" (Switzerland) was used, while in the analysis of the status of the feet, the podoscope "Pedic" (Hungary) was used. A handheld dynamometer "Lafayette" (USA) and tensiometric force platform "Vernier Force Plate" (USA) were used in the analysis of muscle power. Spinal column and feet status were measured in the static condition, with children being in the upright standing position. Muscle power status was measured in both static (a clinician was applying muscle force to the dominant upper extremity of a child trying to overcome or "break" the child's muscle resistance) and dynamic conditions (Counter Movement Jump). Descriptive statistics and correlation analysis were used in data processing by the means of the SPSS software version 24. Results revealed poor postural and muscle power status, and correlations suggesting to possible kinetic chain reaction causing the disruption of the normal postural status in primary school children. Determined postural disorders are characterized by the early functional stage that can be reduced by appropriate corrective exercise programme application and augmented level of proper physical activity. Those programmes and activities are being guided and implemented by physicians and PE teachers in the municipality of Knjaževac.
{"title":"Postural disorders and muscle power in primary school children","authors":"S. Bubanj, Stevan Đorđević, S. Milenkovic, R. Stanković, Mikica Vidojević, Milan Đokić","doi":"10.5937/afmnai38-29283","DOIUrl":"https://doi.org/10.5937/afmnai38-29283","url":null,"abstract":"The aim of the research was to contribute to better understanding of the correlation between postural disorders and muscle power in primary school children. The sample of respondents consisted of 1,120 children, aged 7 to 12 years (549 boys and 571 girls) from the territory of the municipality of Knjaževac. In the assessment of the spinal column status, the device \"Spinal Mouse\" (Switzerland) was used, while in the analysis of the status of the feet, the podoscope \"Pedic\" (Hungary) was used. A handheld dynamometer \"Lafayette\" (USA) and tensiometric force platform \"Vernier Force Plate\" (USA) were used in the analysis of muscle power. Spinal column and feet status were measured in the static condition, with children being in the upright standing position. Muscle power status was measured in both static (a clinician was applying muscle force to the dominant upper extremity of a child trying to overcome or \"break\" the child's muscle resistance) and dynamic conditions (Counter Movement Jump). Descriptive statistics and correlation analysis were used in data processing by the means of the SPSS software version 24. Results revealed poor postural and muscle power status, and correlations suggesting to possible kinetic chain reaction causing the disruption of the normal postural status in primary school children. Determined postural disorders are characterized by the early functional stage that can be reduced by appropriate corrective exercise programme application and augmented level of proper physical activity. Those programmes and activities are being guided and implemented by physicians and PE teachers in the municipality of Knjaževac.","PeriodicalId":7132,"journal":{"name":"Acta Facultatis Medicae Naissensis","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71194979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Areshtanab Namdar, Moonaghi Karimi, M. Vahidi, L. Jouybari, Zeydi Emami, H. Ranjbar
Diagnosis of a chronic disease like type 2 diabetes mellitus (T2DM) is frequently shocking for patients, which influences their lives. Getting aware of bad news such as obtaining a chronic illness diagnosis is a sensitive issue in patients' lives. Conversely, reactions to the reception of a diagnosis of diabetes are often varied for a few reasons. To manage the diseases through care planning, the identification and modification of the causes of various reactions are necessary. The aim of the present survey was to investigate the reaction of diabetics to the reception of diabetes diagnosis and its possible reasons. In this qualitative study, in-depth interviews were used. Furthermore, traditional content analysis of semi-structured interviews was conducted using a qualitative strategy with 20 individuals with type 2 diabetes. The purposeful sampling approach was employed for recruiting the participants. Eleven male and nine female participants having type 2 diabetes had been transferred to the diabetes association of Iran for receiving consulting assistance in the areas of nutrition, psychology, and health care. Four categories of reactions have arisen from the investigation including behavioral, emotional, contextual, and cognitive reactions. Reactions to the prognosis of diabetes may be different for some reasons. The findings of the present investigation may be employed by health care providers to obtain a more comprehensive understanding of unusual and usual reactions, their causes, and the context in the early years after the diagnosis and planning care programs for disease management.
{"title":"Shocked to happy: Experiences of Iranian diabetics in reaction to the bad news of the diagnosis","authors":"Areshtanab Namdar, Moonaghi Karimi, M. Vahidi, L. Jouybari, Zeydi Emami, H. Ranjbar","doi":"10.5937/afmnai38-28720","DOIUrl":"https://doi.org/10.5937/afmnai38-28720","url":null,"abstract":"Diagnosis of a chronic disease like type 2 diabetes mellitus (T2DM) is frequently shocking for patients, which influences their lives. Getting aware of bad news such as obtaining a chronic illness diagnosis is a sensitive issue in patients' lives. Conversely, reactions to the reception of a diagnosis of diabetes are often varied for a few reasons. To manage the diseases through care planning, the identification and modification of the causes of various reactions are necessary. The aim of the present survey was to investigate the reaction of diabetics to the reception of diabetes diagnosis and its possible reasons. In this qualitative study, in-depth interviews were used. Furthermore, traditional content analysis of semi-structured interviews was conducted using a qualitative strategy with 20 individuals with type 2 diabetes. The purposeful sampling approach was employed for recruiting the participants. Eleven male and nine female participants having type 2 diabetes had been transferred to the diabetes association of Iran for receiving consulting assistance in the areas of nutrition, psychology, and health care. Four categories of reactions have arisen from the investigation including behavioral, emotional, contextual, and cognitive reactions. Reactions to the prognosis of diabetes may be different for some reasons. The findings of the present investigation may be employed by health care providers to obtain a more comprehensive understanding of unusual and usual reactions, their causes, and the context in the early years after the diagnosis and planning care programs for disease management.","PeriodicalId":7132,"journal":{"name":"Acta Facultatis Medicae Naissensis","volume":"58 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71195378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tuberculosis (TB) is a contagious disease, and throughout human history, it has been permanently opening numerous medical and legal questions, for which the answers are implied by the current social circumstances. In ancient times, insufficient knowledge of the etiopathogenesis of TB resulted in discrimination and isolation of patients. In the Middle Ages, kings used TB as a disease to secure their political power over the citizens, while TB culturally took a romanticized form during the 19th and 20th centuries, together with a great social phobia of contagion, disease, and dying on the other hand. Stereotypes were formed around all TB victims, while society tried to understand the nature of the disease and establish a civilizational relationship with it as a health problem having numerous social implications. Modern public health measures for the control of the TB pandemic were established after the discovery of the Koch bacillus in the 19th century. The invention and mass use of the BCG vaccine, the discovery of streptomycin and isoniazid, and the new era of TB treatment, with the consequent emergence of drug resistance, coepidemic with AIDS, neglect of public health facilities and the current COVID-19 pandemics threaten many legal rights of the infected and the sick and pose new challenges in its global elimination. Numerous attempts by society over the centuries to devise preventive and therapeutic measures for TB, through different levels of social obligations and activities, have had and continue to have a profound impact on the human race, shaping its further response to the victims of this deadly disease.
{"title":"The burden of tuberculosis as a permanent medical and legal challenge for mankind through centuries","authors":"M. Radović, A. Đorđević, B. Božanić","doi":"10.5937/afmnai38-30478","DOIUrl":"https://doi.org/10.5937/afmnai38-30478","url":null,"abstract":"Tuberculosis (TB) is a contagious disease, and throughout human history, it has been permanently opening numerous medical and legal questions, for which the answers are implied by the current social circumstances. In ancient times, insufficient knowledge of the etiopathogenesis of TB resulted in discrimination and isolation of patients. In the Middle Ages, kings used TB as a disease to secure their political power over the citizens, while TB culturally took a romanticized form during the 19th and 20th centuries, together with a great social phobia of contagion, disease, and dying on the other hand. Stereotypes were formed around all TB victims, while society tried to understand the nature of the disease and establish a civilizational relationship with it as a health problem having numerous social implications. Modern public health measures for the control of the TB pandemic were established after the discovery of the Koch bacillus in the 19th century. The invention and mass use of the BCG vaccine, the discovery of streptomycin and isoniazid, and the new era of TB treatment, with the consequent emergence of drug resistance, coepidemic with AIDS, neglect of public health facilities and the current COVID-19 pandemics threaten many legal rights of the infected and the sick and pose new challenges in its global elimination. Numerous attempts by society over the centuries to devise preventive and therapeutic measures for TB, through different levels of social obligations and activities, have had and continue to have a profound impact on the human race, shaping its further response to the victims of this deadly disease.","PeriodicalId":7132,"journal":{"name":"Acta Facultatis Medicae Naissensis","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71195758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nenad Stošić, J. Popović, Marija Anđelković-Apostolović, A. Mitić, Marija Nikolić, Radomir Barac
One of the primary goals in endodontics is efficient cleaning and shaping of the root canal while maintaining its original configuration. Numerous studies highlight the advantage of using nickel-titanium instruments and the most important is their high flexibility and the ability to penetrate the curved canals. The aim of this study was to analyze the ultrastructure of the surface of nickel-titanium endodontic files before and after use. Eighty-four instruments were included in this study. The instruments were used one, three and six times for root canal preparation on extracted upper premolars. The analysis was performed based on the number of uses and the size of the instruments. Changes on flat surfaces in the grooves of the instruments, defects of the cutting edges and fractures were evaluated. The surface ultrastructure was analyzed on a scanning electron microscope (SEM). SEM analysis showed irregularities on the surfaces of the new instruments. Surface defects and damage of the cutting edges were present after the first use. After three uses, the damage was more evident in instruments of all sizes. After six uses, all instruments showed damage of the cutting edges, and a significant number of fractures were observed. Irregularities on the working parts are already noticed on the new endodontic instruments and originate from the production process. The first signs of damage appear after the first use. In order to prevent errors in clinical work during root canal preparation, it is recommended that the number of instruments uses should be limited.
{"title":"Ultrastructural analysis of the surface changes on the nickel-titanium endodontic instruments after multiple use","authors":"Nenad Stošić, J. Popović, Marija Anđelković-Apostolović, A. Mitić, Marija Nikolić, Radomir Barac","doi":"10.5937/afmnai38-29386","DOIUrl":"https://doi.org/10.5937/afmnai38-29386","url":null,"abstract":"One of the primary goals in endodontics is efficient cleaning and shaping of the root canal while maintaining its original configuration. Numerous studies highlight the advantage of using nickel-titanium instruments and the most important is their high flexibility and the ability to penetrate the curved canals. The aim of this study was to analyze the ultrastructure of the surface of nickel-titanium endodontic files before and after use. Eighty-four instruments were included in this study. The instruments were used one, three and six times for root canal preparation on extracted upper premolars. The analysis was performed based on the number of uses and the size of the instruments. Changes on flat surfaces in the grooves of the instruments, defects of the cutting edges and fractures were evaluated. The surface ultrastructure was analyzed on a scanning electron microscope (SEM). SEM analysis showed irregularities on the surfaces of the new instruments. Surface defects and damage of the cutting edges were present after the first use. After three uses, the damage was more evident in instruments of all sizes. After six uses, all instruments showed damage of the cutting edges, and a significant number of fractures were observed. Irregularities on the working parts are already noticed on the new endodontic instruments and originate from the production process. The first signs of damage appear after the first use. In order to prevent errors in clinical work during root canal preparation, it is recommended that the number of instruments uses should be limited.","PeriodicalId":7132,"journal":{"name":"Acta Facultatis Medicae Naissensis","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71194989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Z. Afshar, A. Babazadeh, M. Javanian, M. Barary, Vasigala Rekha, S. Ebrahimpour
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus strain that caused coronavirus disease 2019 (COVID-19). This novel coronavirus is an emerging global health threat. It caused approximately 140 million confirmed cases, with about 3 million deaths worldwide until April 18, 2021. Although there are two approved medications for this disease, remdesivir and dexamethasone, numerous studies are underway to investigate more therapeutic options. However, so far, most treatments have been supportive, and the clinical efficacy of the suggested drugs is still under consideration. The purpose of this review is to summarize the ongoing treatments, such as several antivirals, convalescent plasma transfusion, and adjunctive medications, with the intent of serving as a clinical guide for the physician and a resource for further evaluations in various clinical trials.
{"title":"A comprehensive review of COVID-19 treatment","authors":"Z. Afshar, A. Babazadeh, M. Javanian, M. Barary, Vasigala Rekha, S. Ebrahimpour","doi":"10.5937/afmnai38-26326","DOIUrl":"https://doi.org/10.5937/afmnai38-26326","url":null,"abstract":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus strain that caused coronavirus disease 2019 (COVID-19). This novel coronavirus is an emerging global health threat. It caused approximately 140 million confirmed cases, with about 3 million deaths worldwide until April 18, 2021. Although there are two approved medications for this disease, remdesivir and dexamethasone, numerous studies are underway to investigate more therapeutic options. However, so far, most treatments have been supportive, and the clinical efficacy of the suggested drugs is still under consideration. The purpose of this review is to summarize the ongoing treatments, such as several antivirals, convalescent plasma transfusion, and adjunctive medications, with the intent of serving as a clinical guide for the physician and a resource for further evaluations in various clinical trials.","PeriodicalId":7132,"journal":{"name":"Acta Facultatis Medicae Naissensis","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71195307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhilla Heydarpoor Damanabad, L. Valizadeh, Sadollah Yeghanedoost, Fariborz Roshangar
In late December 2019, Wuhan, China, became the center of an unknown outbreak of pneumonia that spread rapidly throughout China and around the world, including Iran, and the World Health Organization (WHO) declared the novel disease a public health emergency with global concern. Since the COVID-19 outbreak, many studies have been performed on epidemiological data and clinical signs in adults. However, coherent studies in this field are very rare in infants, and support and attention to infants in the pandemic situation should be doubled due to the weakness and underdevelopment of the neonatal immune system. Therefore, the present study aimed to review COVID-19 infection in infants in which there are discussions on topics such as diagnostic tests, clinical manifestations, recommendations on breastfeeding, the criteria for discharge, and family education in pandemic conditions. The literature review shows no existing evidence of COVID-19 placental transmission from mother to infant, and that all samples prepared from amniotic fluid, umbilical cord blood and breast milk in mothers with COVID -19 was negative for COVID-19 infection, and the clinical manifestations of COVID-19 were non-specific in infants, especially premature infants. Given that there is a limited number of births from a mother with COVID-19, and because the epidemiological and clinical pattern of COVID-19 in infants is unclear, this review study describes diagnostic tests, clinical manifestations, breastfeeding considerations, discharge criteria, and family education in the current understanding of COVID-19 infection in newborns and provides information for better management of SARS-CoV-2 infection in newborns.
{"title":"The 2019 novel coronavirus disease (COVID-19) and neonates","authors":"Zhilla Heydarpoor Damanabad, L. Valizadeh, Sadollah Yeghanedoost, Fariborz Roshangar","doi":"10.5937/AFMNAI38-26743","DOIUrl":"https://doi.org/10.5937/AFMNAI38-26743","url":null,"abstract":"In late December 2019, Wuhan, China, became the center of an unknown outbreak of pneumonia that spread rapidly throughout China and around the world, including Iran, and the World Health Organization (WHO) declared the novel disease a public health emergency with global concern. Since the COVID-19 outbreak, many studies have been performed on epidemiological data and clinical signs in adults. However, coherent studies in this field are very rare in infants, and support and attention to infants in the pandemic situation should be doubled due to the weakness and underdevelopment of the neonatal immune system. Therefore, the present study aimed to review COVID-19 infection in infants in which there are discussions on topics such as diagnostic tests, clinical manifestations, recommendations on breastfeeding, the criteria for discharge, and family education in pandemic conditions. The literature review shows no existing evidence of COVID-19 placental transmission from mother to infant, and that all samples prepared from amniotic fluid, umbilical cord blood and breast milk in mothers with COVID -19 was negative for COVID-19 infection, and the clinical manifestations of COVID-19 were non-specific in infants, especially premature infants. Given that there is a limited number of births from a mother with COVID-19, and because the epidemiological and clinical pattern of COVID-19 in infants is unclear, this review study describes diagnostic tests, clinical manifestations, breastfeeding considerations, discharge criteria, and family education in the current understanding of COVID-19 infection in newborns and provides information for better management of SARS-CoV-2 infection in newborns.","PeriodicalId":7132,"journal":{"name":"Acta Facultatis Medicae Naissensis","volume":"38 1","pages":"18-26"},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71195315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Radenković, M. Velojić-Golubović, D. Radojković, V. Ćirić, R. Kocić
The outcome of diabetes treatments can and should be evaluated through the patients' treatment satisfaction. The aim of this study was to examine the patients' satisfaction with the therapy with human insulin analogues compared with previous treatment with human insulin. We evaluated patient satisfaction in patients with T1DM in our institution who were currently on IIT with human insulins. We performed testing with standard World Health Organization Diabetes Treatment Satisfaction Questionnaire (WHO DTSQ) before and after the therapy with insulin analogs. The overall DTSQ score in forty-nine patients after the third month of therapy and after the sixth month of therapy is higher than before the initiation of therapy (p < 0.001). The results of the responses on the perception of hyperglycaemia were lower after three months of therapy (p < 0.05) and after the six months of treatment than before the onset of therapy (p < 0.01). There were no differences in the perception of hypoglycaemia after three months; however, perception of hypoglycaemia after the sixth month of treatment was lower than before the onset of therapy (p < 0.001) and compared to the score after the third month of therapy (p < 0.01). Therapy of T1DM patients with insulin analogue aspart over three months led to an increase in satisfaction with therapy and a reduction of the perception of hyperglycaemia. Therapy of T1DM patients with insulin analogues (aspart and glargine) over three months led to an increase in satisfaction with therapy and a reduction of the perception of both hyperglycaemia and hypoglycamia.
{"title":"Treatment satisfaction in patients with diabetes mellitus type 1 treated with intensified insulin therapy with insulin analogues","authors":"S. Radenković, M. Velojić-Golubović, D. Radojković, V. Ćirić, R. Kocić","doi":"10.5937/afmnai38-32875","DOIUrl":"https://doi.org/10.5937/afmnai38-32875","url":null,"abstract":"The outcome of diabetes treatments can and should be evaluated through the patients' treatment satisfaction. The aim of this study was to examine the patients' satisfaction with the therapy with human insulin analogues compared with previous treatment with human insulin. We evaluated patient satisfaction in patients with T1DM in our institution who were currently on IIT with human insulins. We performed testing with standard World Health Organization Diabetes Treatment Satisfaction Questionnaire (WHO DTSQ) before and after the therapy with insulin analogs. The overall DTSQ score in forty-nine patients after the third month of therapy and after the sixth month of therapy is higher than before the initiation of therapy (p < 0.001). The results of the responses on the perception of hyperglycaemia were lower after three months of therapy (p < 0.05) and after the six months of treatment than before the onset of therapy (p < 0.01). There were no differences in the perception of hypoglycaemia after three months; however, perception of hypoglycaemia after the sixth month of treatment was lower than before the onset of therapy (p < 0.001) and compared to the score after the third month of therapy (p < 0.01). Therapy of T1DM patients with insulin analogue aspart over three months led to an increase in satisfaction with therapy and a reduction of the perception of hyperglycaemia. Therapy of T1DM patients with insulin analogues (aspart and glargine) over three months led to an increase in satisfaction with therapy and a reduction of the perception of both hyperglycaemia and hypoglycamia.","PeriodicalId":7132,"journal":{"name":"Acta Facultatis Medicae Naissensis","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71195416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Gelevski, G. Jota, L. Todorović, Gjorgji Trajkovski, V. Joksimović, Bojan Trenčić
Situs inversus totalis represents a rare autosomal recessive morphological anomaly of the internal viscera, equally affecting both genders. The genetic defect occurs in the 2nd week of embryonic life, when a 270-degree clockwise rotation of the primitive digestive tube occurs. The incidence of calculosis of gallbladder in patients with situs inversus is the same as in the general population. A 61-year-old female patient with a history of four episodes of colicky, left hypochondrium and epigastric pain, without fever and jaundice, was admitted for elective laparoscopic cholecystectomy. CT of abdomen confirmed situs inversus totalis that was previously known to the patient. The patient was positioned in supine position and a mirror image configuration of the operating room was obtained, with surgeon and scrub nurse on the right side and assistant on the left side of the patient. Four trocars were introduced mirroring the standard position of the 5 mm trocars. During the dissection, second assistant was introduced for the laparoscope, due to the surgeon's limited motor skills in his left hand for delicate dissection, rendering him inapt to perform precise and safe dissection. The total operating time amounted to 110 minutes, which is three times longer than the standard operating time at our institution. The most critical point of the operation in constellation of situs inversus totalis is applying the clips, which requires precision and strength in the same moment. In the available literature, 40 open cholecystectomies before introduction of laparoscopy and 92 laparoscopic cholecystectomies were reported. To our knowledge, this is the first and the only reported laparoscopic cholecystectomy for situs inversus in North Macedonia.
{"title":"Laparoscopic cholecystectomy in situs inversus totalis: A case report","authors":"R. Gelevski, G. Jota, L. Todorović, Gjorgji Trajkovski, V. Joksimović, Bojan Trenčić","doi":"10.5937/afmnai38-30172","DOIUrl":"https://doi.org/10.5937/afmnai38-30172","url":null,"abstract":"Situs inversus totalis represents a rare autosomal recessive morphological anomaly of the internal viscera, equally affecting both genders. The genetic defect occurs in the 2nd week of embryonic life, when a 270-degree clockwise rotation of the primitive digestive tube occurs. The incidence of calculosis of gallbladder in patients with situs inversus is the same as in the general population. A 61-year-old female patient with a history of four episodes of colicky, left hypochondrium and epigastric pain, without fever and jaundice, was admitted for elective laparoscopic cholecystectomy. CT of abdomen confirmed situs inversus totalis that was previously known to the patient. The patient was positioned in supine position and a mirror image configuration of the operating room was obtained, with surgeon and scrub nurse on the right side and assistant on the left side of the patient. Four trocars were introduced mirroring the standard position of the 5 mm trocars. During the dissection, second assistant was introduced for the laparoscope, due to the surgeon's limited motor skills in his left hand for delicate dissection, rendering him inapt to perform precise and safe dissection. The total operating time amounted to 110 minutes, which is three times longer than the standard operating time at our institution. The most critical point of the operation in constellation of situs inversus totalis is applying the clips, which requires precision and strength in the same moment. In the available literature, 40 open cholecystectomies before introduction of laparoscopy and 92 laparoscopic cholecystectomies were reported. To our knowledge, this is the first and the only reported laparoscopic cholecystectomy for situs inversus in North Macedonia.","PeriodicalId":7132,"journal":{"name":"Acta Facultatis Medicae Naissensis","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71195875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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