首页 > 最新文献

Acta radiologica open最新文献

英文 中文
Ultra-low-dose non-contrast CT and CT angiography can be used interchangeably for assessing maximal abdominal aortic diameter. 超低剂量非对比CT和CT血管造影可互换用于评估最大腹主动脉直径。
Pub Date : 2022-10-12 eCollection Date: 2022-10-01 DOI: 10.1177/20584601221132461
Jens Borgbjerg, Heidi S Christensen, Rozh Al-Mashhadi, Martin Bøgsted, Jens B Frøkjær, Lise Medrud, Nis Elbrønd Larsen, Jes S Lindholt

Background: Routine CT scans may increasingly be used to document normal aortic size and to detect incidental abdominal aortic aneurysms.

Purpose: To determine whether ultra-low-dose non-contrast CT (ULDNC-CT) can be used instead of the gold standard CT angiography (CTA) for assessment of maximal abdominal aortic diameter.

Materials and methods: This retrospective study included 50 patients who underwent CTA and a normal-dose non-contrast CT for suspected renal artery stenosis. ULDNC-CT datasets were generated from the normal-dose non-contrast CT datasets using a simulation technique. Using the centerline technique, radiology consultants (n = 4) and residents (n = 3) determined maximal abdominal aortic diameter. The limits of agreement with the mean (LOAM) was used to access observer agreement. LOAM represents how much a measurement by a single observer may plausibly deviate from the mean of all observers on the specific subject.

Results: Observers completed 1400 measurements encompassing repeated CTA and ULDNC-CT measurements. The mean diameter was 24.0 and 25.0 mm for CTA and ULDNC-CT, respectively, yielding a significant but minor mean difference of 1.0 mm. The 95% LOAM reproducibility was similar for CTA and ULDNC-CT (2.3 vs 2.3 mm). In addition, the 95% LOAM and mean diameters were similar for CTA and ULDNC-CT when observers were grouped as consultants and residents.

Conclusions: Ultra-low-dose non-contrast CT exhibited similar accuracy and reproducibility of measurements compared with CTA for assessing maximal abdominal aortic diameter supporting that ULDNC-CT can be used interchangeably with CTA in the lower range of aortic sizes.

背景:常规CT扫描可能越来越多地用于记录正常主动脉大小和发现偶然的腹主动脉瘤。目的:探讨超低剂量非对比CT (ULDNC-CT)是否可以代替金标准CT血管造影(CTA)评估腹主动脉最大内径。材料和方法:本回顾性研究包括50例因怀疑肾动脉狭窄而行CTA和正常剂量非对比CT检查的患者。ULDNC-CT数据集是使用模拟技术从正常剂量非对比CT数据集生成的。利用中心线技术,放射学顾问(n = 4)和住院医师(n = 3)确定了最大腹主动脉直径。使用与均值一致的极限(LOAM)来获取观察者的一致性。LOAM表示单个观察者的测量值与特定主题上所有观察者的平均值的合理偏差程度。结果:观察人员完成了1400次测量,包括重复的CTA和ULDNC-CT测量。CTA和ULDNC-CT的平均直径分别为24.0和25.0 mm,平均相差1.0 mm。CTA和ULDNC-CT的95% LOAM重现性相似(2.3 vs 2.3 mm)。此外,当观察者被分组为顾问和住院医生时,CTA和ULDNC-CT的95% LOAM和平均直径相似。结论:与CTA相比,超低剂量非对比CT在评估最大腹主动脉直径方面具有相似的准确性和可重复性,支持ULDNC-CT可与CTA在主动脉直径较低范围内互换使用。
{"title":"Ultra-low-dose non-contrast CT and CT angiography can be used interchangeably for assessing maximal abdominal aortic diameter.","authors":"Jens Borgbjerg,&nbsp;Heidi S Christensen,&nbsp;Rozh Al-Mashhadi,&nbsp;Martin Bøgsted,&nbsp;Jens B Frøkjær,&nbsp;Lise Medrud,&nbsp;Nis Elbrønd Larsen,&nbsp;Jes S Lindholt","doi":"10.1177/20584601221132461","DOIUrl":"https://doi.org/10.1177/20584601221132461","url":null,"abstract":"<p><strong>Background: </strong>Routine CT scans may increasingly be used to document normal aortic size and to detect incidental abdominal aortic aneurysms.</p><p><strong>Purpose: </strong>To determine whether ultra-low-dose non-contrast CT (ULDNC-CT) can be used instead of the gold standard CT angiography (CTA) for assessment of maximal abdominal aortic diameter.</p><p><strong>Materials and methods: </strong>This retrospective study included 50 patients who underwent CTA and a normal-dose non-contrast CT for suspected renal artery stenosis. ULDNC-CT datasets were generated from the normal-dose non-contrast CT datasets using a simulation technique. Using the centerline technique, radiology consultants (<i>n</i> = 4) and residents (<i>n</i> = 3) determined maximal abdominal aortic diameter. The limits of agreement with the mean (LOAM) was used to access observer agreement. LOAM represents how much a measurement by a single observer may plausibly deviate from the mean of all observers on the specific subject.</p><p><strong>Results: </strong>Observers completed 1400 measurements encompassing repeated CTA and ULDNC-CT measurements. The mean diameter was 24.0 and 25.0 mm for CTA and ULDNC-CT, respectively, yielding a significant but minor mean difference of 1.0 mm. The 95% LOAM reproducibility was similar for CTA and ULDNC-CT (2.3 vs 2.3 mm). In addition, the 95% LOAM and mean diameters were similar for CTA and ULDNC-CT when observers were grouped as consultants and residents.</p><p><strong>Conclusions: </strong>Ultra-low-dose non-contrast CT exhibited similar accuracy and reproducibility of measurements compared with CTA for assessing maximal abdominal aortic diameter supporting that ULDNC-CT can be used interchangeably with CTA in the lower range of aortic sizes.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1e/09/10.1177_20584601221132461.PMC9561642.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33515562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Myxomas and myxoid liposarcomas of the extremities: Our preliminary findings in conventional, perfusion, and diffusion magnetic resonance. 四肢黏液瘤和黏液样脂肪肉瘤:我们在常规、灌注和扩散磁共振中的初步发现。
Pub Date : 2022-10-07 eCollection Date: 2022-10-01 DOI: 10.1177/20584601221131481
Luz M Morán, Jesús Vega, Nieves Gómez-León, Ana Royuela

Background: The differentiation between myxomas and myxoid liposarcomas (MLPS) often is a serious challenge for the radiologists. Magnetic resonance imaging (MRI) is the most useful imaging technique in characterization of the soft tissue tumors (STT).

Purpose: To evaluate in a sample of myxomas and MLPS of the extremities, what morphological findings in conventional MRI allow us to differentiate these two types of myxoid tumors, in addition to analyzing the validity of the apparent diffusion coefficient (ADC) values of diffusion-weighted MRI (DW-MRI).

Material and methods: Magnetic resonance imaging studies in myxomas and MLPS of extremities searched in our PACS between 2015 and 2019. All studies had conventional MRI with T1, T2, and PD SPAIR sequences, while DW-MRI with ADC mapping and perfusion MRI with a T1 sequence repeated for 4 minutes after contrast injection were additional sequences only in some explorations. Two radiologists evaluated independently the MRI studies by examining the qualitative parameters. Apparent diffusion coefficient values were calculated using two methods-ADC global and ADC solid, and Receiver Operating Characteristic (ROC) curves were applied for analysis.

Results: The features were consistent with MLPS: size greater than 10 cm, heterogeneous signal on T1, and nodular enhancement, while the common findings for myxomas were a homogenously hypointense signal on T1 and diffuse peritumoral enhancement. The solid and global ADC values were higher in myxomas. We observed that the solid ADC value less than 2.06 x 10-3mm2 x s would support the diagnosis of MLPS against myxoma.

Conclusion: Overall, MRI with its different modalities improved the diagnostic accuracy when differentiating myxomas from MLPS of extremities.

背景:黏液瘤和黏液样脂肪肉瘤(MLPS)的鉴别对放射科医生来说是一个严峻的挑战。磁共振成像(MRI)是诊断软组织肿瘤(STT)最有用的成像技术。目的:分析弥散加权MRI (DW-MRI)表观弥散系数(ADC)值的有效性,探讨常规MRI中哪些形态学表现能帮助我们区分四肢黏液瘤和MLPS。材料与方法:2015 - 2019年在我们的PACS中检索的四肢黏液瘤和MLPS的磁共振成像研究。所有研究均采用常规MRI T1、T2和PD SPAIR序列,而DW-MRI与ADC作图和灌注MRI在造影剂注射后重复4分钟的T1序列是部分研究的附加序列。两名放射科医生通过检查定性参数独立评估MRI研究。采用ADC全局和实体两种方法计算表观扩散系数值,并采用受试者工作特征(ROC)曲线进行分析。结果:表现与MLPS一致:体积大于10cm, T1呈不均匀信号,结节性强化,而黏液瘤的常见表现为T1呈均匀低信号,肿瘤周围弥漫性强化。固体和整体ADC值在黏液瘤中较高。我们观察到实体ADC值小于2.06 × 10-3mm2 × s,支持MLPS对黏液瘤的诊断。结论:总体而言,不同方式的MRI在鉴别四肢黏液瘤和MLPS时提高了诊断准确性。
{"title":"Myxomas and myxoid liposarcomas of the extremities: Our preliminary findings in conventional, perfusion, and diffusion magnetic resonance.","authors":"Luz M Morán,&nbsp;Jesús Vega,&nbsp;Nieves Gómez-León,&nbsp;Ana Royuela","doi":"10.1177/20584601221131481","DOIUrl":"https://doi.org/10.1177/20584601221131481","url":null,"abstract":"<p><strong>Background: </strong>The differentiation between myxomas and myxoid liposarcomas (MLPS) often is a serious challenge for the radiologists. Magnetic resonance imaging (MRI) is the most useful imaging technique in characterization of the soft tissue tumors (STT).</p><p><strong>Purpose: </strong>To evaluate in a sample of myxomas and MLPS of the extremities, what morphological findings in conventional MRI allow us to differentiate these two types of myxoid tumors, in addition to analyzing the validity of the apparent diffusion coefficient (ADC) values of diffusion-weighted MRI (DW-MRI).</p><p><strong>Material and methods: </strong>Magnetic resonance imaging studies in myxomas and MLPS of extremities searched in our PACS between 2015 and 2019. All studies had conventional MRI with T1, T2, and PD SPAIR sequences, while DW-MRI with ADC mapping and perfusion MRI with a T1 sequence repeated for 4 minutes after contrast injection were additional sequences only in some explorations. Two radiologists evaluated independently the MRI studies by examining the qualitative parameters. Apparent diffusion coefficient values were calculated using two methods-ADC global and ADC solid, and Receiver Operating Characteristic (ROC) curves were applied for analysis.</p><p><strong>Results: </strong>The features were consistent with MLPS: size greater than 10 cm, heterogeneous signal on T1, and nodular enhancement, while the common findings for myxomas were a homogenously hypointense signal on T1 and diffuse peritumoral enhancement. The solid and global ADC values were higher in myxomas. We observed that the solid ADC value less than 2.06 x 10<sup>-3</sup>mm<sup>2</sup> x s would support the diagnosis of MLPS against myxoma.</p><p><strong>Conclusion: </strong>Overall, MRI with its different modalities improved the diagnostic accuracy when differentiating myxomas from MLPS of extremities.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a9/a7/10.1177_20584601221131481.PMC9549112.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33504897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Glioblastoma, IDH-wildtype with leptomeningeal metastasis to Meckel's cave: A case report. 胶质母细胞瘤,idh野生型伴脑膜轻脑膜转移至Meckel穴1例。
Pub Date : 2022-10-07 eCollection Date: 2022-10-01 DOI: 10.1177/20584601221131480
Toshiki Murata, Masazumi Matsuda, Tetsugaku Shinozaki, Koichi Ishiyama

Meckel's cave or the trigeminal cistern is a subarachnoid space near the apex of the petrous portion of the temporal bone and contains cerebrospinal fluid and the Gasserian ganglion, which divides into the ophthalmic (V1), maxillary (V2), and mandibular (V3) nerves. Infectious, inflammatory, congenital, and neoplastic lesions can occur in Meckel's cave. Leptomeningeal metastasis of glioblastoma (GBM), IDH-wildtype to Meckel's cave is rare. We encountered a case of leptomeningeal metastasis of GBM to Meckel's cave in an elderly female patient who presented with pain around her right eye. Magnetic resonance imaging revealed enhancing lesions in the right temporal lobe and cervical spinal cord. The pathological diagnosis of GBM was confirmed after biopsy of the cervical spinal cord lesion, which showed hyperaccumulation of fluorodeoxyglucose (FDG) on FDG-positron emission tomography. This case indicates that metastatic lesions can also occur in Meckel's cave.

Meckel's cave或三叉神经池是靠近颞骨岩部顶端的蛛网膜下腔,包含脑脊液和Gasserian神经节,分为眼神经(V1)、上颌神经(V2)和下颌神经(V3)。感染性、炎性、先天性和肿瘤性病变可发生在梅克尔氏洞。胶质母细胞瘤(GBM), idh野生型向Meckel穴转移是罕见的。我们遇到了一例GBM的脑膜转移到梅克尔洞的老年女性患者,她表现为右眼周围疼痛。磁共振成像显示右侧颞叶和颈脊髓病变增强。颈脊髓病变活检证实病理诊断为GBM, FDG-正电子发射断层扫描显示氟脱氧葡萄糖(FDG)过度积聚。这个病例表明转移性病变也可能发生在梅克尔氏洞。
{"title":"Glioblastoma, IDH-wildtype with leptomeningeal metastasis to Meckel's cave: A case report.","authors":"Toshiki Murata,&nbsp;Masazumi Matsuda,&nbsp;Tetsugaku Shinozaki,&nbsp;Koichi Ishiyama","doi":"10.1177/20584601221131480","DOIUrl":"https://doi.org/10.1177/20584601221131480","url":null,"abstract":"<p><p>Meckel's cave or the trigeminal cistern is a subarachnoid space near the apex of the petrous portion of the temporal bone and contains cerebrospinal fluid and the Gasserian ganglion, which divides into the ophthalmic (V1), maxillary (V2), and mandibular (V3) nerves. Infectious, inflammatory, congenital, and neoplastic lesions can occur in Meckel's cave. Leptomeningeal metastasis of glioblastoma (GBM), IDH-wildtype to Meckel's cave is rare. We encountered a case of leptomeningeal metastasis of GBM to Meckel's cave in an elderly female patient who presented with pain around her right eye. Magnetic resonance imaging revealed enhancing lesions in the right temporal lobe and cervical spinal cord. The pathological diagnosis of GBM was confirmed after biopsy of the cervical spinal cord lesion, which showed hyperaccumulation of fluorodeoxyglucose (FDG) on FDG-positron emission tomography. This case indicates that metastatic lesions can also occur in Meckel's cave.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/72/bc/10.1177_20584601221131480.PMC9549091.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33504899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A survey of local diagnostic reference levels for the head, thorax, abdomen and pelvis computed tomography in Norway and Canada. 挪威和加拿大的头部、胸部、腹部和骨盆计算机断层扫描诊断参考水平的调查。
Pub Date : 2022-10-07 eCollection Date: 2022-10-01 DOI: 10.1177/20584601221131477
Elena Tonkopi, Eline Jahre Wikan, Tor Olav Hovland, Sivert Høgset, Thomas Alexander Kofod, Selasi K Sefenu, Emily Hughes-Ryan, Dakota D Entremont-O Connell, Catherine Gunn, Tanja Holter, Safora Johansen

Background: Computed tomography (CT) contributes to 60% of the collective dose in medical imaging. Literature has demonstrated that patient dose varies across regions and countries. Establishing diagnostic reference levels (DRLs) contributes to the optimization of clinical practices and radiation protection.

Purpose: To survey the dose indices (CTDIvol and dose-length product) for frequently performed CT examinations from the chosen hospitals in Norway and Canada and to determine local DRLs (LDRLs) based on the collected data.

Material and methods: The survey included eight scanners from two Norwegian hospitals and four scanners from four Canadian hospitals. Dosimetry data were collected for the following routine CT examinations: head, contrast-enhanced thorax, and abdomen and pelvis. Overall 480 adult average-sized patients from Norway and 360 from Canada were included in the survey. The LDRLs were determined as the 75th percentile of distributions of median values of dose indicators from different CT scanners. The differences in dose between scanners were determined using single-factor ANOVA.

Results: The LDRLs determined in Norway were higher overall than in Canada. The obtained values were compared to the national DRLs. The dose from several scanners in Norway exceeded national Norwegian DRLs, while Canadian LDRLs were below the Canadian reference levels. The differences between the means of the dose distributions from each scanner were statistically significant (p < 0.05) for all examinations with exception of identical scanners located in the same hospital and using the same protocols.

Conclusion: Observed dose variations even in the same hospital, or from the same scanner model confirmed the need for CT protocol optimization.

背景:计算机断层扫描(CT)在医学成像中占总剂量的60%。文献表明,患者剂量因区域和国家而异。建立诊断参考水平(drl)有助于优化临床实践和辐射防护。目的:调查挪威和加拿大选定医院CT检查的剂量指数(CTDIvol和剂量长度乘积),并根据收集的数据确定当地的DRLs (LDRLs)。材料和方法:调查包括来自两家挪威医院的8台扫描仪和来自四家加拿大医院的4台扫描仪。收集剂量学数据用于以下常规CT检查:头部、胸部、腹部和骨盆。共有来自挪威的480名成人平均体型患者和来自加拿大的360名患者参与了调查。LDRLs由不同CT扫描仪剂量指标中位数分布的第75百分位数确定。使用单因素方差分析确定扫描仪之间的剂量差异。结果:挪威的LDRLs总体上高于加拿大。将所得值与国家drl进行比较。挪威几台扫描仪的剂量超过了挪威国家最低限度,而加拿大的最低限度则低于加拿大的参考水平。除了位于同一医院并使用相同方案的相同扫描仪外,所有检查中每个扫描仪剂量分布平均值之间的差异具有统计学意义(p < 0.05)。结论:即使在同一家医院,或来自同一台扫描仪型号,所观察到的剂量差异也证实了CT方案优化的必要性。
{"title":"A survey of local diagnostic reference levels for the head, thorax, abdomen and pelvis computed tomography in Norway and Canada.","authors":"Elena Tonkopi,&nbsp;Eline Jahre Wikan,&nbsp;Tor Olav Hovland,&nbsp;Sivert Høgset,&nbsp;Thomas Alexander Kofod,&nbsp;Selasi K Sefenu,&nbsp;Emily Hughes-Ryan,&nbsp;Dakota D Entremont-O Connell,&nbsp;Catherine Gunn,&nbsp;Tanja Holter,&nbsp;Safora Johansen","doi":"10.1177/20584601221131477","DOIUrl":"https://doi.org/10.1177/20584601221131477","url":null,"abstract":"<p><strong>Background: </strong>Computed tomography (CT) contributes to 60% of the collective dose in medical imaging. Literature has demonstrated that patient dose varies across regions and countries. Establishing diagnostic reference levels (DRLs) contributes to the optimization of clinical practices and radiation protection.</p><p><strong>Purpose: </strong>To survey the dose indices (CTDIvol and dose-length product) for frequently performed CT examinations from the chosen hospitals in Norway and Canada and to determine local DRLs (LDRLs) based on the collected data.</p><p><strong>Material and methods: </strong>The survey included eight scanners from two Norwegian hospitals and four scanners from four Canadian hospitals. Dosimetry data were collected for the following routine CT examinations: head, contrast-enhanced thorax, and abdomen and pelvis. Overall 480 adult average-sized patients from Norway and 360 from Canada were included in the survey. The LDRLs were determined as the 75th percentile of distributions of median values of dose indicators from different CT scanners. The differences in dose between scanners were determined using single-factor ANOVA.</p><p><strong>Results: </strong>The LDRLs determined in Norway were higher overall than in Canada. The obtained values were compared to the national DRLs. The dose from several scanners in Norway exceeded national Norwegian DRLs, while Canadian LDRLs were below the Canadian reference levels. The differences between the means of the dose distributions from each scanner were statistically significant (<i>p</i> < 0.05) for all examinations with exception of identical scanners located in the same hospital and using the same protocols.</p><p><strong>Conclusion: </strong>Observed dose variations even in the same hospital, or from the same scanner model confirmed the need for CT protocol optimization.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c7/69/10.1177_20584601221131477.PMC9549116.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33504898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantitative bone SPECT/CT for evaluating treatment response in patient with sternoclavicular arthritis. 定量骨SPECT/CT评价胸锁骨关节炎患者的治疗效果。
Pub Date : 2022-10-04 eCollection Date: 2022-10-01 DOI: 10.1177/20584601221128409
Hisashi Komoto, Kazuhiro Kitajima, Naoto Azuma, Masao Tamura, Hiroyuki Yokoyama, Tatsuya Tsuchitani, Koichiro Yamakado

We report here a case of sternoclavicular arthritis due to SAPHO syndrome in a 60-year-old female in which quantitative values determined using bone SPECT/CT were useful to evaluate response. After celecoxib and alendronate sodium hydrate therapy, the chief complaints were well relieved and post-treatment Tc-99m HMDP bone SPECT/CT examination showed decreased uptake. The maximum standardized uptake value (SUV), peak SUV, mean SUV, metabolic bone volume, and total bone uptake of the untreated lesion were 18, 16, 10, 17 mL, and 180, respectively, which were decreased to 8, 7, 5, 15 mL, and 75, respectively, after the treatment. In comparison with pre-treatment situation, those parameters were decreased by -56%, -56%, -50%, -12%, and -58%, respectively, following celecoxib and alendronate sodium hydrate therapy, likely reflecting treatment response. Quantitative bone SPECT/CT may be useful to evaluate joint inflammatory activity and treatment response in a patient with osteoartritis.

我们在此报告一例60岁女性因SAPHO综合征而患胸锁关节炎的病例,其中使用骨SPECT/CT确定的定量值有助于评估反应。在塞来昔布和阿仑膦酸钠治疗后,主诉得到了很好的缓解,治疗后Tc-99m HMDP骨SPECT/CT检查显示摄取减少。未治疗病变的最大标准化摄取值(SUV)、峰值SUV、平均SUV、代谢骨体积和总骨摄取分别为18、16、10、17 mL和180,治疗后分别降至8、7、5、15 mL和75。与治疗前相比,塞来昔布和阿仑膦酸钠治疗后,这些参数分别下降了-56%、-56%、-50%、-12%和-58%,可能反映了治疗效果。定量骨SPECT/CT可能有助于评估骨关节炎患者的关节炎症活动和治疗反应。
{"title":"Quantitative bone SPECT/CT for evaluating treatment response in patient with sternoclavicular arthritis.","authors":"Hisashi Komoto,&nbsp;Kazuhiro Kitajima,&nbsp;Naoto Azuma,&nbsp;Masao Tamura,&nbsp;Hiroyuki Yokoyama,&nbsp;Tatsuya Tsuchitani,&nbsp;Koichiro Yamakado","doi":"10.1177/20584601221128409","DOIUrl":"https://doi.org/10.1177/20584601221128409","url":null,"abstract":"<p><p>We report here a case of sternoclavicular arthritis due to SAPHO syndrome in a 60-year-old female in which quantitative values determined using bone SPECT/CT were useful to evaluate response. After celecoxib and alendronate sodium hydrate therapy, the chief complaints were well relieved and post-treatment Tc-99m HMDP bone SPECT/CT examination showed decreased uptake. The maximum standardized uptake value (SUV), peak SUV, mean SUV, metabolic bone volume, and total bone uptake of the untreated lesion were 18, 16, 10, 17 mL, and 180, respectively, which were decreased to 8, 7, 5, 15 mL, and 75, respectively, after the treatment. In comparison with pre-treatment situation, those parameters were decreased by -56%, -56%, -50%, -12%, and -58%, respectively, following celecoxib and alendronate sodium hydrate therapy, likely reflecting treatment response. Quantitative bone SPECT/CT may be useful to evaluate joint inflammatory activity and treatment response in a patient with osteoartritis.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3f/73/10.1177_20584601221128409.PMC9536095.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33517221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case of Schistosoma japonicum retroperitoneal pseudotumor diagnosed by cone-beam CT-guided coaxial biopsy system. 锥形束ct引导同轴活检诊断日本血吸虫腹膜后假瘤1例。
Pub Date : 2022-09-24 eCollection Date: 2022-09-01 DOI: 10.1177/20584601221129153
Shu Matsushita, Shinichi Hamamoto, Ryo Morita, Michinori Shirano, Takeshi Inoue, Tomohisa Okuma, Takao Manabe

We report a rare case of retroperitoneal pseudotumor caused by Schistosoma japonicum that was diagnosed by computed tomography (CT) guided percutaneous biopsy in a 15-year-old Filipino male. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed a mass lesion, including a mesenteric artery, in the right retroperitoneal space. His mother had a history of S. japonicum infection but his initial stool examination was negative. As schistosomiasis was suspected, cone-beam CT-guided biopsy was performed to enable transcatheter therapeutic arterial embolization to be performed immediately in the event of hemorrhage. Histopathological examination revealed schistosomal eggs. Cone-beam CT-guided technique with a coaxial biopsy system is a safe and accurate diagnostic procedure for S. japonicum retroperitoneal pseudotumor.

我们报告一例罕见的由日本血吸虫引起的腹膜后假瘤,在15岁的菲律宾男性中通过计算机断层扫描(CT)引导下经皮活检诊断。计算机断层扫描(CT)和磁共振成像(MRI)显示肿块病变,包括肠系膜动脉,在右侧腹膜后间隙。其母亲有日本血吸虫感染史,但初步大便检查呈阴性。当怀疑为血吸虫病时,进行了锥束ct引导活检,以便在出血时立即进行经导管治疗性动脉栓塞。组织病理学检查发现血吸虫卵。锥形束ct引导技术与同轴活检系统是一种安全、准确的诊断日本血吸虫腹膜后假性肿瘤的方法。
{"title":"A case of Schistosoma japonicum retroperitoneal pseudotumor diagnosed by cone-beam CT-guided coaxial biopsy system.","authors":"Shu Matsushita,&nbsp;Shinichi Hamamoto,&nbsp;Ryo Morita,&nbsp;Michinori Shirano,&nbsp;Takeshi Inoue,&nbsp;Tomohisa Okuma,&nbsp;Takao Manabe","doi":"10.1177/20584601221129153","DOIUrl":"https://doi.org/10.1177/20584601221129153","url":null,"abstract":"<p><p>We report a rare case of retroperitoneal pseudotumor caused by <i>Schistosoma japonicum</i> that was diagnosed by computed tomography (CT) guided percutaneous biopsy in a 15-year-old Filipino male. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed a mass lesion, including a mesenteric artery, in the right retroperitoneal space. His mother had a history of <i>S. japonicum</i> infection but his initial stool examination was negative. As schistosomiasis was suspected, cone-beam CT-guided biopsy was performed to enable transcatheter therapeutic arterial embolization to be performed immediately in the event of hemorrhage. Histopathological examination revealed schistosomal eggs. Cone-beam CT-guided technique with a coaxial biopsy system is a safe and accurate diagnostic procedure for <i>S. japonicum</i> retroperitoneal pseudotumor.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/87/7d/10.1177_20584601221129153.PMC9513577.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40385665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High volume retrograde portography for better discrimination of the portal vein during TIPS procedure. 高容量逆行门静脉造影,以便在TIPS手术中更好地识别门静脉。
Pub Date : 2022-09-20 eCollection Date: 2022-09-01 DOI: 10.1177/20584601221128405
J Altenbernd, S Zimmer, L Andrae, B Labonte, J Gruber, H Beier, M Abdulgader, M Buechter, M Forsting, J Theysohn

Background: Imaging of the portal vein prior to puncture for TIPS is essential. Purpose: With this study, we examined a modified retrograde portography with regard to the reliable representation of the portal vein. Material and Methods: Prospective evaluation of 65 TIPS interventions with regard to the delimitation of the portal vein and the exact parameters of retrograde portography such as catheter diameter and contrast medium volume per injection. Results: Retrograde portographies with a large-lumen catheter (10 F) and a large contrast medium volume (40 mL) were performed in 35/63 patients with significantly better delineation of the portal vein than when using 5 F catheters with 10 mL contrast medium. Conclusion: The so-called high volume retrograde portography leads to better delimitation of the portal vein during TIPS application.

背景:门静脉造影在TIPS穿刺前是必要的。目的:在这项研究中,我们检查了一种改良的逆行门静脉造影,以可靠地表示门静脉。材料与方法:65项TIPS干预措施的前瞻性评价,涉及门静脉的划分和逆行门静脉造影的确切参数,如导管直径和每次注射造影剂体积。结果:35/63例患者行大腔导管(10f)和大造影剂体积(40ml)逆行门静脉造影,门静脉的描绘明显优于使用5f导管和10ml造影剂。结论:在应用TIPS时,所谓的高容量逆行门静脉造影可以更好地划分门静脉。
{"title":"High volume retrograde portography for better discrimination of the portal vein during TIPS procedure.","authors":"J Altenbernd,&nbsp;S Zimmer,&nbsp;L Andrae,&nbsp;B Labonte,&nbsp;J Gruber,&nbsp;H Beier,&nbsp;M Abdulgader,&nbsp;M Buechter,&nbsp;M Forsting,&nbsp;J Theysohn","doi":"10.1177/20584601221128405","DOIUrl":"https://doi.org/10.1177/20584601221128405","url":null,"abstract":"<p><p><b>Background:</b> Imaging of the portal vein prior to puncture for TIPS is essential. <b>Purpose:</b> With this study, we examined a modified retrograde portography with regard to the reliable representation of the portal vein. <b>Material and Methods:</b> Prospective evaluation of 65 TIPS interventions with regard to the delimitation of the portal vein and the exact parameters of retrograde portography such as catheter diameter and contrast medium volume per injection. <b>Results:</b> Retrograde portographies with a large-lumen catheter (10 F) and a large contrast medium volume (40 mL) were performed in 35/63 patients with significantly better delineation of the portal vein than when using 5 F catheters with 10 mL contrast medium. <b>Conclusion:</b> The so-called high volume retrograde portography leads to better delimitation of the portal vein during TIPS application.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9493682/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33482822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Brown tumor mimicking metastases-the late manifestation of hyperparathyroidism. 模拟转移的棕色肿瘤-甲状旁腺功能亢进的晚期表现。
Pub Date : 2022-09-17 eCollection Date: 2022-09-01 DOI: 10.1177/20584601221128415
Louise Tram, Magdalena Kubik, Kristina Kvist Jensen, Charlotte E Almasi

Brown tumors are uncommon manifestations of hyperparathyroidism (HPT) that without awareness are easily misdiagnosed as metastases. This short report highlights the importance of clinical context and clear communication between medical specialties when interpreting complex radiologic findings.

褐色肿瘤是甲状旁腺功能亢进(HPT)的罕见表现,在没有意识的情况下容易误诊为转移。这篇简短的报告强调了在解释复杂的放射学发现时临床背景和医学专业之间清晰沟通的重要性。
{"title":"Brown tumor mimicking metastases-the late manifestation of hyperparathyroidism.","authors":"Louise Tram,&nbsp;Magdalena Kubik,&nbsp;Kristina Kvist Jensen,&nbsp;Charlotte E Almasi","doi":"10.1177/20584601221128415","DOIUrl":"https://doi.org/10.1177/20584601221128415","url":null,"abstract":"<p><p>Brown tumors are uncommon manifestations of hyperparathyroidism (HPT) that without awareness are easily misdiagnosed as metastases. This short report highlights the importance of clinical context and clear communication between medical specialties when interpreting complex radiologic findings.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/41/51/10.1177_20584601221128415.PMC9484045.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33466321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tunneled hemodialysis catheter insertion: Above, within, or below the right atrium-Where is the tip? 隧道式血液透析导管置入:右心房上方、内部或下方——导管尖端在哪里?
Pub Date : 2022-09-01 DOI: 10.1177/20584601221122421
Jonas Auer, Joachim Braun, Julian Lenk, Johannes Gollrad, Sa-Ra Ro, Bernd Hamm, Maximilian de Bucourt

Background: One major challenge when inserting a tunneled, cuffed central venous catheter (CVC) for hemodialysis under fluoroscopy is to accurately place the catheter tip by assessing its position in relation to the cardiac silhouette to approximate the right atrium (RA).

Purpose: To investigate whether a weighted mean calculated from published results for two two-dimensional landmark reference distances may be useful in assessing CVC tip positions in relation to the RA.

Material and methods: Central venous catheter tip positions attained under fluoroscopic imaging during insertion using the cardiac silhouette as approximation were retrospectively related to two reference distances (carina to cranial RA border and craniocaudal RA extent), which were used to group catheter tip locations above (1), within (2), or below (3) the RA (henceforth referred to as landmark technique approximation, LTA). The LTA-derived catheter tip locations were validated by correlation with postinterventional computed tomography (CT) datasets acquired shortly after implantation (if available).

Results: Based on LTA, 45 catheter tips (10.6%) were above, 179 (42.2%) within, and 200 (47.2%) below the RA. Postinterventional CT (n = 57; 13.4%) visualized 26.3% above, 66.7% within, and 7.0% below the RA.

Conclusion: The LTA reference distances appear to lead to a rather low categorization of the CVC tips, or the tips have been placed rather low in the study population. Validation using postinterventional CT indicated an underestimation of the RA in the LTA. Patient characteristics with a higher risk of false estimation through LTA have been defined.

背景:在透视下插入用于血液透析的隧道式中心静脉导管(CVC)的一个主要挑战是通过评估导管尖端与心脏轮廓的关系来准确放置导管尖端,以接近右心房(RA)。目的:研究两个二维地标参考距离的加权平均值是否可用于评估与RA相关的CVC尖端位置。材料和方法:在插入过程中,使用心脏轮廓作为近似,在透视成像下获得的中心静脉导管尖端位置与两个参考距离(隆突到颅侧RA边界和颅侧RA范围)回顾性相关,这些参考距离用于将导管尖端位置分组在(1)之上,(2)之内或(3)之下(以下称为地标技术近似,LTA)。lta衍生的导管尖端位置通过与植入后(如果可用)获得的介入后计算机断层扫描(CT)数据集的相关性进行验证。结果:基于LTA,导管尖端在RA以上的有45个(10.6%),在RA以内的有179个(42.2%),低于RA的有200个(47.2%)。介入后CT (n = 57;13.4%)高于RA 26.3%,低于RA 66.7%,低于RA 7.0%。结论:LTA参考距离似乎导致CVC提示的分类相当低,或者提示在研究人群中的位置相当低。介入后CT验证显示低估了LTA的RA。已经定义了通过LTA进行错误估计风险较高的患者特征。
{"title":"Tunneled hemodialysis catheter insertion: Above, within, or below the right atrium-Where is the tip?","authors":"Jonas Auer,&nbsp;Joachim Braun,&nbsp;Julian Lenk,&nbsp;Johannes Gollrad,&nbsp;Sa-Ra Ro,&nbsp;Bernd Hamm,&nbsp;Maximilian de Bucourt","doi":"10.1177/20584601221122421","DOIUrl":"https://doi.org/10.1177/20584601221122421","url":null,"abstract":"<p><strong>Background: </strong>One major challenge when inserting a tunneled, cuffed central venous catheter (CVC) for hemodialysis under fluoroscopy is to accurately place the catheter tip by assessing its position in relation to the cardiac silhouette to approximate the right atrium (RA).</p><p><strong>Purpose: </strong>To investigate whether a weighted mean calculated from published results for two two-dimensional landmark reference distances may be useful in assessing CVC tip positions in relation to the RA.</p><p><strong>Material and methods: </strong>Central venous catheter tip positions attained under fluoroscopic imaging during insertion using the cardiac silhouette as approximation were retrospectively related to two reference distances (carina to cranial RA border and craniocaudal RA extent), which were used to group catheter tip locations above (1), within (2), or below (3) the RA (henceforth referred to as landmark technique approximation, LTA). The LTA-derived catheter tip locations were validated by correlation with postinterventional computed tomography (CT) datasets acquired shortly after implantation (if available).</p><p><strong>Results: </strong>Based on LTA, 45 catheter tips (10.6%) were above, 179 (42.2%) within, and 200 (47.2%) below the RA. Postinterventional CT (<i>n</i> = 57; 13.4%) visualized 26.3% above, 66.7% within, and 7.0% below the RA.</p><p><strong>Conclusion: </strong>The LTA reference distances appear to lead to a rather low categorization of the CVC tips, or the tips have been placed rather low in the study population. Validation using postinterventional CT indicated an underestimation of the RA in the LTA. Patient characteristics with a higher risk of false estimation through LTA have been defined.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a5/bd/10.1177_20584601221122421.PMC9483979.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9318100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radioactive seed localization of foreign body. 放射性种子定位异物。
Pub Date : 2022-08-16 eCollection Date: 2022-08-01 DOI: 10.1177/20584601221088922
Sine Hylenius, Wei Uldall, Gro Qvamme, Niels Kroman

Radioactive seed localization is a method widely used within breast cancer treatment. This case represents a 43-year-old male patient with a foreign body in his left axilla. We used radioactive seed localization for marking the foreign body, which made the subsequent surgery possible, quick, and minimal invasive.

放射性种子定位是一种广泛应用于乳腺癌治疗的方法。本病例为一43岁男性左腋窝异物患者。我们使用放射性种子定位来标记异物,这使得后续手术成为可能,快速,微创。
{"title":"Radioactive seed localization of foreign body.","authors":"Sine Hylenius,&nbsp;Wei Uldall,&nbsp;Gro Qvamme,&nbsp;Niels Kroman","doi":"10.1177/20584601221088922","DOIUrl":"https://doi.org/10.1177/20584601221088922","url":null,"abstract":"<p><p>Radioactive seed localization is a method widely used within breast cancer treatment. This case represents a 43-year-old male patient with a foreign body in his left axilla. We used radioactive seed localization for marking the foreign body, which made the subsequent surgery possible, quick, and minimal invasive.</p>","PeriodicalId":72063,"journal":{"name":"Acta radiologica open","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/37/05/10.1177_20584601221088922.PMC9386870.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40715456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
期刊
Acta radiologica open
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1