Pub Date : 2001-11-11DOI: 10.1115/imece2001/bed-23158
C. Baicu, M. Zile
Pathological processes which cause diastolic congestive heart failure (CHF), such as pressure overload hypertrophy (POH), produce abnormalities in the material properties of cardiac muscle cells (cardiomyocytes) and may selectively alter its elastic stiffness, viscosity, or both. Previous methods used to characterize these cardiomyocyte viscoelastic properties were constrained by specific biological and engineering limitations, which prevented testing in conditions that mimic normal physiology. The current study proposes an uniaxial variable-rate stretching method, in which isolated cardiomyocytes embedded in a three-dimensional gel matrix were subjected to stretch. Physiological Ca++ (2.5 mM) and rapid stretch rates up to 100 μm/sec provided experimental conditions parallel to in vivo physiology. The proposed method identified and individually quantified both cellular stiffness and viscosity, and showed that POH increased both elastic and viscous cardiomyocyte diastolic properties.
{"title":"Quantification of Diastolic Viscoelastic Properties of Isolated Cardiac Muscle Cells","authors":"C. Baicu, M. Zile","doi":"10.1115/imece2001/bed-23158","DOIUrl":"https://doi.org/10.1115/imece2001/bed-23158","url":null,"abstract":"\u0000 Pathological processes which cause diastolic congestive heart failure (CHF), such as pressure overload hypertrophy (POH), produce abnormalities in the material properties of cardiac muscle cells (cardiomyocytes) and may selectively alter its elastic stiffness, viscosity, or both. Previous methods used to characterize these cardiomyocyte viscoelastic properties were constrained by specific biological and engineering limitations, which prevented testing in conditions that mimic normal physiology. The current study proposes an uniaxial variable-rate stretching method, in which isolated cardiomyocytes embedded in a three-dimensional gel matrix were subjected to stretch. Physiological Ca++ (2.5 mM) and rapid stretch rates up to 100 μm/sec provided experimental conditions parallel to in vivo physiology. The proposed method identified and individually quantified both cellular stiffness and viscosity, and showed that POH increased both elastic and viscous cardiomyocyte diastolic properties.","PeriodicalId":7238,"journal":{"name":"Advances in Bioengineering","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2001-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86772880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2001-11-11DOI: 10.1115/imece2001/bed-23054
M. Koff, T. Gardner, E. Balaguer, C. Kawcak, C. McIlwraith, V. Mow
Osteochondral diseases occur within ail bones and cartilages of the equine carpus and can lead to loss of athletic use and occasionally catastrophic injury that necessitate euthanasia. The intensity and direction of stresses that lead to such injuries are unknown. Joint modeling is a commonly used technique in human orthopaedic research that allows investigators to determine the internal stresses of joints. Through the use of computer models, various scenarios, such as ligament damage, can be simulated and changes in the resulting joint surface stresses determined [1]. The purpose of this study was to experimentally obtain precise quantitative contact area data of the articular surfaces of the distal radius, the proximal and distal aspects of the radial carpal bone and the proximal aspect of the 3rd carpal bone of the equine carpus. These data provide normative contact and cartilage thickness values for the equine carpus that will facilitate the use of this joint as a large animal model for osteoarthritis studies. Furthermore, these experimental data will serve as the basis for the development and calibration of an equine carpus whole joint computer model.
{"title":"Precise Quantitative Models of the Equine Articular Carpus Anatomy and Contact Areas","authors":"M. Koff, T. Gardner, E. Balaguer, C. Kawcak, C. McIlwraith, V. Mow","doi":"10.1115/imece2001/bed-23054","DOIUrl":"https://doi.org/10.1115/imece2001/bed-23054","url":null,"abstract":"\u0000 Osteochondral diseases occur within ail bones and cartilages of the equine carpus and can lead to loss of athletic use and occasionally catastrophic injury that necessitate euthanasia. The intensity and direction of stresses that lead to such injuries are unknown. Joint modeling is a commonly used technique in human orthopaedic research that allows investigators to determine the internal stresses of joints. Through the use of computer models, various scenarios, such as ligament damage, can be simulated and changes in the resulting joint surface stresses determined [1]. The purpose of this study was to experimentally obtain precise quantitative contact area data of the articular surfaces of the distal radius, the proximal and distal aspects of the radial carpal bone and the proximal aspect of the 3rd carpal bone of the equine carpus. These data provide normative contact and cartilage thickness values for the equine carpus that will facilitate the use of this joint as a large animal model for osteoarthritis studies. Furthermore, these experimental data will serve as the basis for the development and calibration of an equine carpus whole joint computer model.","PeriodicalId":7238,"journal":{"name":"Advances in Bioengineering","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2001-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87787578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2001-11-11DOI: 10.1115/imece2001/bed-23047
R. Patterson, M. El-shennawy, Koji Nakamura, S. Viegas
Carpometacarpal joint motion has been difficult to accurately measure with standard methods. There has been relatively little information on the kinematics of the 2nd through 5th carpometacapal (CMC) joints. It is however, generally accepted that the range of motion in the 2nd through the 5th CMC joints increases from the radial to the ulnar side of the hand, with the 2nd CMC joint being essentially immobile, while the 5th CMC joint simultaneously flexes and adducts1. The purpose of this study is to investigate the 3D dynamic kinematics of the 2nd – 5th CMC joints during flexion/extension motion (FEM), radio-ulnar deviation (RUD), and pronation/supination motion (PSM).
{"title":"3D Kinematic Analysis of the Carpometacarpal Joints","authors":"R. Patterson, M. El-shennawy, Koji Nakamura, S. Viegas","doi":"10.1115/imece2001/bed-23047","DOIUrl":"https://doi.org/10.1115/imece2001/bed-23047","url":null,"abstract":"\u0000 Carpometacarpal joint motion has been difficult to accurately measure with standard methods. There has been relatively little information on the kinematics of the 2nd through 5th carpometacapal (CMC) joints. It is however, generally accepted that the range of motion in the 2nd through the 5th CMC joints increases from the radial to the ulnar side of the hand, with the 2nd CMC joint being essentially immobile, while the 5th CMC joint simultaneously flexes and adducts1. The purpose of this study is to investigate the 3D dynamic kinematics of the 2nd – 5th CMC joints during flexion/extension motion (FEM), radio-ulnar deviation (RUD), and pronation/supination motion (PSM).","PeriodicalId":7238,"journal":{"name":"Advances in Bioengineering","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2001-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89562351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2001-11-11DOI: 10.1115/imece2001/bed-23144
Terri-Ann N. Kelly, C. C. Wang, N. Chahine, G. Ateshian, C. Hung
An understanding of chondrocyte mechanotransduction requires knowledge of the deformational fields within the tissue. Since the study of chondrocyte mechanotransduction in articular cartilage explants is hampered by its inhomogeneous biochemical composition and biomechanical properties, investigators have performed loading studies of chondrocyte-suspended hydrogel polymer systems such as agarose [1]. Prior to significant matrix elaboration by the cells, the agarose offers a uniform, uncharged three-dimensional (3D) mechanical environment for chondrocytes [2,3]. In this study, a technique, which combines video microscopy [4] and digital image correlation [5], was used to provide a novel characterization of the temporal changes in displacement field, apparent Young’s Modulus and apparent Poisson’s ratio of free swelling chondrocyte-seeded agarose constructs. Biochemical analysis was performed to permit correlation of these parameters with matrix elaboration.
{"title":"Temporal Development of Material Properties in Free Swelling Chondrocyte-Seeded Agarose Constructs","authors":"Terri-Ann N. Kelly, C. C. Wang, N. Chahine, G. Ateshian, C. Hung","doi":"10.1115/imece2001/bed-23144","DOIUrl":"https://doi.org/10.1115/imece2001/bed-23144","url":null,"abstract":"\u0000 An understanding of chondrocyte mechanotransduction requires knowledge of the deformational fields within the tissue. Since the study of chondrocyte mechanotransduction in articular cartilage explants is hampered by its inhomogeneous biochemical composition and biomechanical properties, investigators have performed loading studies of chondrocyte-suspended hydrogel polymer systems such as agarose [1]. Prior to significant matrix elaboration by the cells, the agarose offers a uniform, uncharged three-dimensional (3D) mechanical environment for chondrocytes [2,3]. In this study, a technique, which combines video microscopy [4] and digital image correlation [5], was used to provide a novel characterization of the temporal changes in displacement field, apparent Young’s Modulus and apparent Poisson’s ratio of free swelling chondrocyte-seeded agarose constructs. Biochemical analysis was performed to permit correlation of these parameters with matrix elaboration.","PeriodicalId":7238,"journal":{"name":"Advances in Bioengineering","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2001-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89940394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2001-11-11DOI: 10.1115/imece2001/bed-23130
C. Sadasivan, B. Lieber, D. Lopes, A. Ringer, L. Hopkins
The ultimate goal in the treatment of cerebral aneurysms is to exclude them from the intracranial circulation while preserving the parent artery. Recently, in vivo and in vitro experiments and clinical studies demonstrated that endovascular stenting is a significant and viable treatment option for cerebral aneurysms. Stents reduce the mass and momentum transport of blood from the parent artery into the aneurysm and alter both intra-aneurysmal flow and inflow-outflow patterns. The reduction of vorticity and flow stasis within the sac leads to thrombus formation and eventual exclusion of the aneurysm from the circulation. Digital subtraction angiography (DSA) has become an essential clinical tool for the diagnosis and treatment of aneurysms and is an important adjunct to stenting procedures.
{"title":"Modeling of Angiographic Dye Washout From Cerebral Aneurysms Before and After Stenting: An Index for Stent Efficacy","authors":"C. Sadasivan, B. Lieber, D. Lopes, A. Ringer, L. Hopkins","doi":"10.1115/imece2001/bed-23130","DOIUrl":"https://doi.org/10.1115/imece2001/bed-23130","url":null,"abstract":"\u0000 The ultimate goal in the treatment of cerebral aneurysms is to exclude them from the intracranial circulation while preserving the parent artery. Recently, in vivo and in vitro experiments and clinical studies demonstrated that endovascular stenting is a significant and viable treatment option for cerebral aneurysms. Stents reduce the mass and momentum transport of blood from the parent artery into the aneurysm and alter both intra-aneurysmal flow and inflow-outflow patterns. The reduction of vorticity and flow stasis within the sac leads to thrombus formation and eventual exclusion of the aneurysm from the circulation. Digital subtraction angiography (DSA) has become an essential clinical tool for the diagnosis and treatment of aneurysms and is an important adjunct to stenting procedures.","PeriodicalId":7238,"journal":{"name":"Advances in Bioengineering","volume":"72 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2001-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84528083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2001-11-11DOI: 10.1115/imece2001/bed-23070
E. Wang
Off-Road bicycle suspension systems are beneficial because they dissipate vibrational energy and a lower vibration dosage can reduce the metabolic energy expenditure of the cyclist [1]. However, dampers dissipate energy and the energy dissipated must be compensated by additional input from the cyclist. Estimates of the energy dissipated range from 1–2% of the total power input by the cyclist [2–4]. Additionally, suspension systems add weight to a bicycle, which also requires additional energy when hill climbing and accelerating.
{"title":"Measuring the Efficiency of Off-Road Bicycle Suspension Systems","authors":"E. Wang","doi":"10.1115/imece2001/bed-23070","DOIUrl":"https://doi.org/10.1115/imece2001/bed-23070","url":null,"abstract":"\u0000 Off-Road bicycle suspension systems are beneficial because they dissipate vibrational energy and a lower vibration dosage can reduce the metabolic energy expenditure of the cyclist [1]. However, dampers dissipate energy and the energy dissipated must be compensated by additional input from the cyclist. Estimates of the energy dissipated range from 1–2% of the total power input by the cyclist [2–4]. Additionally, suspension systems add weight to a bicycle, which also requires additional energy when hill climbing and accelerating.","PeriodicalId":7238,"journal":{"name":"Advances in Bioengineering","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2001-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79195747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2001-11-11DOI: 10.1115/imece2001/bed-23033
Wei Lin, C. Rubin, Yi-Xian Qin
Osteoporosis is characterized by the non-traumatic fracture due to the deterioration of bone properties. Although there is a consensus that the loss of bone mass is the key factor to osteoporosis, the bone material strength and trabecular architecture are also important in the contribution to the whole bone strength. Ultrasound is mechanical in nature and it has the potential to assess the bone density as well as its mechanical stiffness. Ultrasound attenuation is one of the ultrasound parameters used to assess bone properties. Studies have shown that ultrasound attenuation is dependent on bone density [1,2] and is also indicative to the strength of trabecular bone [3,4]. Therefore, ultrasound attenuation has the potential to reveal bone properties. The objective of this study is to develop a frequency scanning method that can better extract the information of not only the bone quantity but also the bone quality.
{"title":"Measurment of Broadband Ultrasound Attenuation Using Tone Burst Frequency Scanning in Trabecular Bone Property Assessment","authors":"Wei Lin, C. Rubin, Yi-Xian Qin","doi":"10.1115/imece2001/bed-23033","DOIUrl":"https://doi.org/10.1115/imece2001/bed-23033","url":null,"abstract":"\u0000 Osteoporosis is characterized by the non-traumatic fracture due to the deterioration of bone properties. Although there is a consensus that the loss of bone mass is the key factor to osteoporosis, the bone material strength and trabecular architecture are also important in the contribution to the whole bone strength. Ultrasound is mechanical in nature and it has the potential to assess the bone density as well as its mechanical stiffness. Ultrasound attenuation is one of the ultrasound parameters used to assess bone properties. Studies have shown that ultrasound attenuation is dependent on bone density [1,2] and is also indicative to the strength of trabecular bone [3,4]. Therefore, ultrasound attenuation has the potential to reveal bone properties. The objective of this study is to develop a frequency scanning method that can better extract the information of not only the bone quantity but also the bone quality.","PeriodicalId":7238,"journal":{"name":"Advances in Bioengineering","volume":"80 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2001-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83830159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2001-11-11DOI: 10.1115/imece2001/bed-23095
V. Houston, G. Luo, C. P. Mason, M. Mussman, M. Garbarini, A. C. Beattie, C. Thongpop
Foot problems are quite common. Epidemiological studies have shown as many as 86% of elderly individuals report having problems with their feet, ranging from calluses, cracking and ingrown nails to inflammation, swelling, ischemia, ulceration, and gangrenous necrosis [1]. Persons suffering chronic Diabetes Mellitus are at particular risk of trauma to their feet because of peripheral neuropathy, plantar fat pad and muscle atrophy, and vascular insufficiency. Half of all lower limb amputations each year in the United States are performed on diabetics because of foot and ankle injuries that fail to heal [2]. At the very least, podalgia and pedal trauma restrict person’s mobility and limit their independence, impacting their fiscal as well as their physical well-being. With the exception of memorable catastrophic events, the etiopathogenesis of podalgia and other problems contributing to pedal trauma are generally not well understood. In work with Hansen’s disease and diabetic patients, Brand et al. [3] showed that stresses as small as 1/2 psi could produce trauma in the foot fat pads of even healthy animals, if chronically and repetitively applied without adequate time for tissues to recover and rest, Pedorthic insoles (often with orthopedic shoes) are prescribed for curative as well as prophylactic treatment of podalgia and pedal trauma, especially for diabetic patients with peripheral vascular disease, and arthritic patients with osseous deformity. There are hundreds of such devices commercially available, that range in composition and mechanical characteristics from extremely soft silicone elastomers to stiff plastic and metal plates. They maybe thin or thick, flat or custom milled with precision CAD/CAM systems using 3D laser scans of the individual’s feet to match their pedal contours. Although numerous studies [4, 5, 6] have been conducted, measuring pedal plantar interface stresses, no general quantitative principles for design, performance assessment, or prescription have been developed. These procedures remain highly subjective, and quite variable, depending upon the training, experience, and skill of the patient’s pedorthotist, podiatrist, and/or physcian. The objective of this study was to investigate the stresses and strains incurred in the soft plantar tissues of the foot as a function of insole material and design geometry to enhance understanding of footwear biomechanics and contribute to development of quantitative criteria for prescription, design, and performance assessment of pedorthic footwear.
{"title":"FEA Optimization of Pedorthic Treatment for Podalgia","authors":"V. Houston, G. Luo, C. P. Mason, M. Mussman, M. Garbarini, A. C. Beattie, C. Thongpop","doi":"10.1115/imece2001/bed-23095","DOIUrl":"https://doi.org/10.1115/imece2001/bed-23095","url":null,"abstract":"\u0000 Foot problems are quite common. Epidemiological studies have shown as many as 86% of elderly individuals report having problems with their feet, ranging from calluses, cracking and ingrown nails to inflammation, swelling, ischemia, ulceration, and gangrenous necrosis [1]. Persons suffering chronic Diabetes Mellitus are at particular risk of trauma to their feet because of peripheral neuropathy, plantar fat pad and muscle atrophy, and vascular insufficiency. Half of all lower limb amputations each year in the United States are performed on diabetics because of foot and ankle injuries that fail to heal [2]. At the very least, podalgia and pedal trauma restrict person’s mobility and limit their independence, impacting their fiscal as well as their physical well-being. With the exception of memorable catastrophic events, the etiopathogenesis of podalgia and other problems contributing to pedal trauma are generally not well understood. In work with Hansen’s disease and diabetic patients, Brand et al. [3] showed that stresses as small as 1/2 psi could produce trauma in the foot fat pads of even healthy animals, if chronically and repetitively applied without adequate time for tissues to recover and rest, Pedorthic insoles (often with orthopedic shoes) are prescribed for curative as well as prophylactic treatment of podalgia and pedal trauma, especially for diabetic patients with peripheral vascular disease, and arthritic patients with osseous deformity. There are hundreds of such devices commercially available, that range in composition and mechanical characteristics from extremely soft silicone elastomers to stiff plastic and metal plates. They maybe thin or thick, flat or custom milled with precision CAD/CAM systems using 3D laser scans of the individual’s feet to match their pedal contours. Although numerous studies [4, 5, 6] have been conducted, measuring pedal plantar interface stresses, no general quantitative principles for design, performance assessment, or prescription have been developed. These procedures remain highly subjective, and quite variable, depending upon the training, experience, and skill of the patient’s pedorthotist, podiatrist, and/or physcian. The objective of this study was to investigate the stresses and strains incurred in the soft plantar tissues of the foot as a function of insole material and design geometry to enhance understanding of footwear biomechanics and contribute to development of quantitative criteria for prescription, design, and performance assessment of pedorthic footwear.","PeriodicalId":7238,"journal":{"name":"Advances in Bioengineering","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2001-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78741380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2001-11-11DOI: 10.1115/imece2001/bed-23109
N. Macia
This paper presents the application of a planar, fluid amplifier which has been used as a bi-stable element in an intermittent, oxygen delivery device. The proportional fluid amplifier is made bi-stable by positive feedback: by connecting its outputs to its inputs, through a fluid resistor network. The fluidic fluid amplifier is the device that gave birth to the fluidics technology, in 1959, at the former Harry Diamond Laboratories (U.S. Army).
{"title":"Applications of a Microfluidic Amplifier As a Bi-Stable Device in an Oxygen Delivery System","authors":"N. Macia","doi":"10.1115/imece2001/bed-23109","DOIUrl":"https://doi.org/10.1115/imece2001/bed-23109","url":null,"abstract":"\u0000 This paper presents the application of a planar, fluid amplifier which has been used as a bi-stable element in an intermittent, oxygen delivery device. The proportional fluid amplifier is made bi-stable by positive feedback: by connecting its outputs to its inputs, through a fluid resistor network. The fluidic fluid amplifier is the device that gave birth to the fluidics technology, in 1959, at the former Harry Diamond Laboratories (U.S. Army).","PeriodicalId":7238,"journal":{"name":"Advances in Bioengineering","volume":"95 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2001-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78184035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2001-11-11DOI: 10.1115/imece2001/bed-23106
A. Al-Jumaily, Y. Du
This research focuses on establishing an appropriate theoretical technique for identifying an obstruction in a flexible compliant tube such as the trachea. The input impedance frequency spectrums for both a healthy and an obstructed airway are used as a signature to determine and examine the constriction location, severity and degree. Uniform and gradual types of constriction are considered and the results demonstrate that the input impedance resonant frequencies can map the location, severity and degree of an obstruction.
{"title":"Obstruction Detection in the Upper Airways Using Input Impedance in the Frequency Domain","authors":"A. Al-Jumaily, Y. Du","doi":"10.1115/imece2001/bed-23106","DOIUrl":"https://doi.org/10.1115/imece2001/bed-23106","url":null,"abstract":"\u0000 This research focuses on establishing an appropriate theoretical technique for identifying an obstruction in a flexible compliant tube such as the trachea. The input impedance frequency spectrums for both a healthy and an obstructed airway are used as a signature to determine and examine the constriction location, severity and degree. Uniform and gradual types of constriction are considered and the results demonstrate that the input impedance resonant frequencies can map the location, severity and degree of an obstruction.","PeriodicalId":7238,"journal":{"name":"Advances in Bioengineering","volume":"140 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2001-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77962999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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