Pub Date : 2001-11-11DOI: 10.1115/imece2001/bed-23003
H. Hayashi, T. Ohashi, D. Mori, T. Yamaguchi
It is very important to elucidate the specific mechanism for the formation, growth, and breakdown of coronary plaque, in order to diagnose and prevent ischemic heart disease, such as myocardial infarction. Coronary atherosclerotic plaque has some characteristic background conditions from a mechanical viewpoint. Of these, the beating motion of the heart wall on which the major coronary arteries are fixed is very interesting, due to its possible mechanical influence on the flow inside the artery, and hence on atherogenesis. This study conducted a computational flow dynamics (CFD) simulation using a simplified model of the right coronary artery, which deforms with contraction of the heart. The right coronary artery was modeled using an ordinary helix, whose torsion and curvature changed in time with the contraction and dilatation of the heart. The results are discussed with respect to local hemodynamics’ characteristics, particularly the wall shear stress distribution.
{"title":"Computational Fluid Dynamics Model Analysis of the Blood Flow in the Right Coronary Artery on the Beating Heart","authors":"H. Hayashi, T. Ohashi, D. Mori, T. Yamaguchi","doi":"10.1115/imece2001/bed-23003","DOIUrl":"https://doi.org/10.1115/imece2001/bed-23003","url":null,"abstract":"\u0000 It is very important to elucidate the specific mechanism for the formation, growth, and breakdown of coronary plaque, in order to diagnose and prevent ischemic heart disease, such as myocardial infarction. Coronary atherosclerotic plaque has some characteristic background conditions from a mechanical viewpoint. Of these, the beating motion of the heart wall on which the major coronary arteries are fixed is very interesting, due to its possible mechanical influence on the flow inside the artery, and hence on atherogenesis. This study conducted a computational flow dynamics (CFD) simulation using a simplified model of the right coronary artery, which deforms with contraction of the heart. The right coronary artery was modeled using an ordinary helix, whose torsion and curvature changed in time with the contraction and dilatation of the heart. The results are discussed with respect to local hemodynamics’ characteristics, particularly the wall shear stress distribution.","PeriodicalId":7238,"journal":{"name":"Advances in Bioengineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82553606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2001-11-11DOI: 10.1115/imece2001/bed-23010
D. M. Brey, Xu Yang, R. Keynton, Thomas J. Rousse, W. Ehringer, J. Alexander
The most common cause for chronic term (> 30 days) failure of vascular bypass grafts is the rapid growth of underlying tissues within arteries called intimal hyperplasia (EH) [1]. IH has been found to primarily exist in low wall shear stress regions within distal anastomoses [2]; however, the exact mechanism by which shear stress induces IH has not been ascertained. We hypothesize that endothelial lining permeability is induced by wall shear stress during tissue reorganization such as occurs within vascular bypass constructs. Occludin is an adhesion protein that is actively involved in endothelial cell (EC) tight junctions, and thus, may effect EC layer permeability. To date, no studies have been conducted to determine the effect of wall shear stress on this adhesion protein. Therefore, the purpose of this study is to evaluate the role of wall shear stress upon the expression of occludin within cultured endothelial cells.
{"title":"Effects of Wall Shear Stress on the Expression of Occludin in Human Umbilical Vein Endothelial Cells","authors":"D. M. Brey, Xu Yang, R. Keynton, Thomas J. Rousse, W. Ehringer, J. Alexander","doi":"10.1115/imece2001/bed-23010","DOIUrl":"https://doi.org/10.1115/imece2001/bed-23010","url":null,"abstract":"\u0000 The most common cause for chronic term (> 30 days) failure of vascular bypass grafts is the rapid growth of underlying tissues within arteries called intimal hyperplasia (EH) [1]. IH has been found to primarily exist in low wall shear stress regions within distal anastomoses [2]; however, the exact mechanism by which shear stress induces IH has not been ascertained. We hypothesize that endothelial lining permeability is induced by wall shear stress during tissue reorganization such as occurs within vascular bypass constructs. Occludin is an adhesion protein that is actively involved in endothelial cell (EC) tight junctions, and thus, may effect EC layer permeability. To date, no studies have been conducted to determine the effect of wall shear stress on this adhesion protein. Therefore, the purpose of this study is to evaluate the role of wall shear stress upon the expression of occludin within cultured endothelial cells.","PeriodicalId":7238,"journal":{"name":"Advances in Bioengineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82076597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2001-11-11DOI: 10.1115/imece2001/bed-23105
A. Al-Jumaily, Y. Du
The frequency spectrum of the input impedance determined at the throat is analysed to identify partial occlusion in the branched central bronchi. The airways are modelled starting from the trachea to the second generation and the result demonstrates that the input impedance resonant frequencies can map the location, severity and degree of an obstruction in any of the considered branches.
{"title":"Simulation of the Central Airways for Identifying Airway Partial Obstruction","authors":"A. Al-Jumaily, Y. Du","doi":"10.1115/imece2001/bed-23105","DOIUrl":"https://doi.org/10.1115/imece2001/bed-23105","url":null,"abstract":"\u0000 The frequency spectrum of the input impedance determined at the throat is analysed to identify partial occlusion in the branched central bronchi. The airways are modelled starting from the trachea to the second generation and the result demonstrates that the input impedance resonant frequencies can map the location, severity and degree of an obstruction in any of the considered branches.","PeriodicalId":7238,"journal":{"name":"Advances in Bioengineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82934528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2001-11-11DOI: 10.1115/imece2001/bed-23006
Matthew J. Chatham, B. A. Todd, J. Parker, Audrey S. House, Jenny L. Taylor
Bone mineral density loss has been observed in astronauts who have spent a significant amount of time in a micro-gravity environment [1]. The lack of mechanical stress placed on the bones while in this environment is a major factor in the decrease in bone mineral density. To counteract these effects, resistive exercise has been the focus of many studies. Weighted plates have been used to provide a constant force resistance in ground-based bed rest studies. Bed rest has been established as one of the best ways to simulate the long-term effects of micro-gravity on earth [2]. In weightlessness, however, an alternate source of resistive force is required Some exercise devices provide resistance with elastic bands. Unfortunately, these elastic bands tend to lose their mechanical stiffness with use, requiring many spare elastic bands to be available for long duration missions in space. A more robust system that requires less maintenance would be preferable. Metallic helical springs meet this requirement The mechanical properties of helical springs are predictable, and these springs have a long life, making them well suited for long duration missions. However, helical springs exhibit linear behavior. That is, the resistive force provided by the spring is directly proportional to the amount of deflection. Therefore, a mechanism was designed to interact with the linear springs to provide a constant output force over a given length of travel.
{"title":"A Spring-Loaded Constant Force Exercise Device","authors":"Matthew J. Chatham, B. A. Todd, J. Parker, Audrey S. House, Jenny L. Taylor","doi":"10.1115/imece2001/bed-23006","DOIUrl":"https://doi.org/10.1115/imece2001/bed-23006","url":null,"abstract":"\u0000 Bone mineral density loss has been observed in astronauts who have spent a significant amount of time in a micro-gravity environment [1]. The lack of mechanical stress placed on the bones while in this environment is a major factor in the decrease in bone mineral density. To counteract these effects, resistive exercise has been the focus of many studies. Weighted plates have been used to provide a constant force resistance in ground-based bed rest studies. Bed rest has been established as one of the best ways to simulate the long-term effects of micro-gravity on earth [2]. In weightlessness, however, an alternate source of resistive force is required Some exercise devices provide resistance with elastic bands. Unfortunately, these elastic bands tend to lose their mechanical stiffness with use, requiring many spare elastic bands to be available for long duration missions in space. A more robust system that requires less maintenance would be preferable. Metallic helical springs meet this requirement The mechanical properties of helical springs are predictable, and these springs have a long life, making them well suited for long duration missions. However, helical springs exhibit linear behavior. That is, the resistive force provided by the spring is directly proportional to the amount of deflection. Therefore, a mechanism was designed to interact with the linear springs to provide a constant output force over a given length of travel.","PeriodicalId":7238,"journal":{"name":"Advances in Bioengineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80764890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2001-11-11DOI: 10.1115/imece2001/bed-23087
Jason P. Halloran, P. Rullkoetter
The success of current total knee replacement (TKR) devices is contingent on the kinematics and contact mechanics during in vivo physiological activity. A great deal of research has gone into determining parameters important to proper long-term joint function. Indicators of potential wear performance in ultra-high molecular weight polyethylene (UHMWPE) total joint replacement components include contact stress and area due to articulations, and tibio-femoral and patello-femoral kinematics. All have been used to compare implant designs and serve as a basis for differentiation of systems.
{"title":"A Total Knee Replacement Model for Evaluation of Joint Mechanics","authors":"Jason P. Halloran, P. Rullkoetter","doi":"10.1115/imece2001/bed-23087","DOIUrl":"https://doi.org/10.1115/imece2001/bed-23087","url":null,"abstract":"\u0000 The success of current total knee replacement (TKR) devices is contingent on the kinematics and contact mechanics during in vivo physiological activity. A great deal of research has gone into determining parameters important to proper long-term joint function. Indicators of potential wear performance in ultra-high molecular weight polyethylene (UHMWPE) total joint replacement components include contact stress and area due to articulations, and tibio-femoral and patello-femoral kinematics. All have been used to compare implant designs and serve as a basis for differentiation of systems.","PeriodicalId":7238,"journal":{"name":"Advances in Bioengineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84806309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2001-11-11DOI: 10.1115/imece2001/bed-23015
Yi Zhang, H. Asada
A Hybrid Adaptive Kalman Filter (HAKF), consisting of a continuous Standard Kalman Filter (SKF) and an intermittent Least Squares Parameter Estimator (LSPE), is proposed to calibrate the hemodynamic model for continuous arterial pressure monitoring. Simulations of the HAKF using a classic Windkessel model are carried out to prove the principle of the proposal.
{"title":"Hybrid Adaptive Kalman Filter: Calibrating a Hemodynamic Model for Continuous Arterial Pressure Monitoring","authors":"Yi Zhang, H. Asada","doi":"10.1115/imece2001/bed-23015","DOIUrl":"https://doi.org/10.1115/imece2001/bed-23015","url":null,"abstract":"\u0000 A Hybrid Adaptive Kalman Filter (HAKF), consisting of a continuous Standard Kalman Filter (SKF) and an intermittent Least Squares Parameter Estimator (LSPE), is proposed to calibrate the hemodynamic model for continuous arterial pressure monitoring. Simulations of the HAKF using a classic Windkessel model are carried out to prove the principle of the proposal.","PeriodicalId":7238,"journal":{"name":"Advances in Bioengineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76556488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2001-11-11DOI: 10.1115/imece2001/bed-23050
W. Houchaime, A. Petrella, T. Dietz, J. Halloran, P. Rullkoetter
Polyethylene wear has been implicated in osteolysis and can lead eventually to implant loosening. Abrasive/adhesive wear and delamination or pitting damage in ultra-high molecular weight polyethylene (UHMWPE) joint replacement components has been in part attributed to high joint contact stresses. The propensity of total joint replacement systems for these types of wear is often assessed by evaluating the joint contact stresses and contact areas and these often serve as a basis for differentiation of systems. The rate-dependency of polyethylene can have a significant effect on these contact characteristics of joint replacement components. Previously, researchers have used experimental and analytical methods to determine joint contact characteristics. Most of the analytical studies, however, have not included the important time-dependent behavior of UHWMPE.
{"title":"Development of a Rate-Dependent Material Model for UHMWPE Joint Replacement Components","authors":"W. Houchaime, A. Petrella, T. Dietz, J. Halloran, P. Rullkoetter","doi":"10.1115/imece2001/bed-23050","DOIUrl":"https://doi.org/10.1115/imece2001/bed-23050","url":null,"abstract":"\u0000 Polyethylene wear has been implicated in osteolysis and can lead eventually to implant loosening. Abrasive/adhesive wear and delamination or pitting damage in ultra-high molecular weight polyethylene (UHMWPE) joint replacement components has been in part attributed to high joint contact stresses. The propensity of total joint replacement systems for these types of wear is often assessed by evaluating the joint contact stresses and contact areas and these often serve as a basis for differentiation of systems. The rate-dependency of polyethylene can have a significant effect on these contact characteristics of joint replacement components. Previously, researchers have used experimental and analytical methods to determine joint contact characteristics. Most of the analytical studies, however, have not included the important time-dependent behavior of UHWMPE.","PeriodicalId":7238,"journal":{"name":"Advances in Bioengineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76625269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2001-11-11DOI: 10.1115/imece2001/bed-23097
M. Parkinson, Jane Huggins
Decubitous ulcers (“pressure sores”) are a significant concern for people using wheelchairs. In fact, results published by the University of Kansas [1] indicate that over half of those using wheelchairs will develop a pressure sore at some point. This susceptibility is due to the conditions under which these ulcers develop: shear stress and pressure work together to cut off the blood supply to the surface tissue, which subsequently dies. Heat and moisture can increase the likelihood of this necrosis and the rate at which it occurs. Although sores can develop quickly (onset can occur in as few as fifteen minutes), they may take months to heal. Appropriate seat cushion selection helps to mitigate the causative factors [2]. In particular, custom-contoured cushions (CCC) can offer dramatic improvements. Research has shown that CCC’s offer the best distribution of pressure and reduction of shear stress, reducing these factors by as much as 80% [3]. CCC’s are not commonly used, however, because the cost and time involved in design, manufacture, and delivery are prohibitive. The obstacles of cost, time, and inconvenience, can be overcome by applying mass-customization and rapid-prototyping principles to the process used to create CCC’s. This involves automating the basic steps of the process: creating an electronic representation of the seating surface and machining that surface using a computer-controlled (CNC) mill. Similar systems have been put in place to automate a variety of processes, from the creation of custom orthotics for footwear to the design and creation of impeller wheels [4]. Such a system would be capable of producing a suitable custom-contoured cushion in minutes or hours rather than weeks or months.
褥疮(“压疮”)是使用轮椅的人非常关心的问题。事实上，堪萨斯大学(University of Kansas)发表的研究结果[1]表明，超过一半使用轮椅的人会在某个时候出现压疮。这种易感性是由于这些溃疡形成的条件:剪切应力和压力共同作用，切断了表面组织的血液供应，随后死亡。高温和潮湿会增加这种坏死的可能性和发生的速度。尽管溃疡发展迅速(15分钟内就会发作)，但可能需要数月才能愈合。选择合适的坐垫有助于减轻致病因素[2]。特别地，定制形状的坐垫(CCC)可以提供显著的改善。研究表明，CCC提供了最佳的压力分布和剪切应力降低，将这些因素降低了80%[3]。然而，CCC并不常用，因为设计、制造和交付所涉及的成本和时间令人望而却步。成本，时间和不便的障碍，可以通过大规模定制和快速原型设计原则，用于创建CCC的过程中克服。这包括自动化加工过程的基本步骤:创建座位表面的电子表示，并使用计算机控制(CNC)铣床加工该表面。类似的系统已经到位，以实现各种流程的自动化，从鞋类定制矫形器的创建到叶轮轮的设计和创建[4]。这样的系统将能够在几分钟或几小时内而不是几周或几个月内生产出合适的定制形状的垫子。
{"title":"A Method for the Rapid Prototyping of Custom Contoured Cushions","authors":"M. Parkinson, Jane Huggins","doi":"10.1115/imece2001/bed-23097","DOIUrl":"https://doi.org/10.1115/imece2001/bed-23097","url":null,"abstract":"\u0000 Decubitous ulcers (“pressure sores”) are a significant concern for people using wheelchairs. In fact, results published by the University of Kansas [1] indicate that over half of those using wheelchairs will develop a pressure sore at some point. This susceptibility is due to the conditions under which these ulcers develop: shear stress and pressure work together to cut off the blood supply to the surface tissue, which subsequently dies. Heat and moisture can increase the likelihood of this necrosis and the rate at which it occurs. Although sores can develop quickly (onset can occur in as few as fifteen minutes), they may take months to heal.\u0000 Appropriate seat cushion selection helps to mitigate the causative factors [2]. In particular, custom-contoured cushions (CCC) can offer dramatic improvements. Research has shown that CCC’s offer the best distribution of pressure and reduction of shear stress, reducing these factors by as much as 80% [3]. CCC’s are not commonly used, however, because the cost and time involved in design, manufacture, and delivery are prohibitive.\u0000 The obstacles of cost, time, and inconvenience, can be overcome by applying mass-customization and rapid-prototyping principles to the process used to create CCC’s. This involves automating the basic steps of the process: creating an electronic representation of the seating surface and machining that surface using a computer-controlled (CNC) mill. Similar systems have been put in place to automate a variety of processes, from the creation of custom orthotics for footwear to the design and creation of impeller wheels [4]. Such a system would be capable of producing a suitable custom-contoured cushion in minutes or hours rather than weeks or months.","PeriodicalId":7238,"journal":{"name":"Advances in Bioengineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78024896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2001-11-11DOI: 10.1115/imece2001/bed-23058
C. Spoon, J. Wayne
The indentation test is a commonly used experimental setup to determine properties of articular cartilage, both in the laboratory and as a clinical tool, as it is a test that can be performed in situ. Behavior of normal cartilage and tissue generated in reparative studies have been thus obtained [1, 2, 3]. It has been shown from a finite element study [4] that the behavior of cartilage in indentation stress relaxation can be affected by the tissue width relative to the radius of the indenter. Another finite element study of the indentation of osteochondral defects showed that this ratio also affected specifications of boundary conditions [5]. This investigation sought to evaluate the effect of changing geometric parameters (e.g. tissue width and indenter radius) on the properties determined from creep indentation experiments.
{"title":"Indentation of Articular Cartilage: Effects of Specimen Radius on Determined Properties","authors":"C. Spoon, J. Wayne","doi":"10.1115/imece2001/bed-23058","DOIUrl":"https://doi.org/10.1115/imece2001/bed-23058","url":null,"abstract":"\u0000 The indentation test is a commonly used experimental setup to determine properties of articular cartilage, both in the laboratory and as a clinical tool, as it is a test that can be performed in situ. Behavior of normal cartilage and tissue generated in reparative studies have been thus obtained [1, 2, 3]. It has been shown from a finite element study [4] that the behavior of cartilage in indentation stress relaxation can be affected by the tissue width relative to the radius of the indenter. Another finite element study of the indentation of osteochondral defects showed that this ratio also affected specifications of boundary conditions [5]. This investigation sought to evaluate the effect of changing geometric parameters (e.g. tissue width and indenter radius) on the properties determined from creep indentation experiments.","PeriodicalId":7238,"journal":{"name":"Advances in Bioengineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74856656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2001-11-11DOI: 10.1115/imece2001/bed-23019
G. Livesay, K. Dee, E. Nauman, R. T. Hart
In the Fall of 1999, the Department of Biomedical Engineering at Tulane University significantly revised the undergraduate curriculum to both increase the biomedical engineering content and move this BMEN content earlier in the students’ BMEN career. A major component of this revision was the introduction of bridge courses designed to ‘bridge’ from traditional engineering topics to biomedical engineering topics in the major sub-disciplines within biomedical engineering -Bioelectronics, Bioelectricity, Cell & Tissue Engineering, Biomaterials, and Biomechanics.
{"title":"Active Learning in Mechanics Courses in Biomedical Engineering","authors":"G. Livesay, K. Dee, E. Nauman, R. T. Hart","doi":"10.1115/imece2001/bed-23019","DOIUrl":"https://doi.org/10.1115/imece2001/bed-23019","url":null,"abstract":"\u0000 In the Fall of 1999, the Department of Biomedical Engineering at Tulane University significantly revised the undergraduate curriculum to both increase the biomedical engineering content and move this BMEN content earlier in the students’ BMEN career. A major component of this revision was the introduction of bridge courses designed to ‘bridge’ from traditional engineering topics to biomedical engineering topics in the major sub-disciplines within biomedical engineering -Bioelectronics, Bioelectricity, Cell & Tissue Engineering, Biomaterials, and Biomechanics.","PeriodicalId":7238,"journal":{"name":"Advances in Bioengineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85391538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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