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Instability Analysis of a Cervical Spine Model Under Flexion and Compression Loading 屈曲和压缩载荷下颈椎模型的不稳定性分析
Pub Date : 2001-11-11 DOI: 10.1115/imece2001/bed-23041
A. Tchako, A. Sadegh
An improved and detailed 3-D FE model of human cervical spine was created using digitized geometric measurement. The model was validated with the in-vivo studies of Moroney, Panjabi and Fuller. Clinical instability of the spine for two cases involving flexion and compression loading (simulating injuries in motorcycle vaulting, football and diving accidents) were analyzed. The instability was based on the check list of Panjabi and White. It was determined that flexion moment of 10 Nm or compressive force of 500N result in the onset of clinical instability.
采用数字化几何测量技术,建立了改进的、精细的人体颈椎三维有限元模型。通过Moroney, Panjabi和Fuller的体内研究验证了该模型。本文分析了两例涉及屈曲和压缩负荷(模拟摩托车跳跃、足球和跳水事故损伤)的脊柱临床不稳定性。这种不稳定是基于旁遮普和怀特的核对表。确定10 Nm的弯曲力矩或500N的压缩力导致临床不稳定的发生。
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引用次数: 0
Effect of Variations in Intraluminal Thrombus Constitutive Properties on Abdominal Aortic Aneurysm Wall Stress: A Parametric Study 腔内血栓本构性变化对腹主动脉瘤壁应力的影响:一项参数研究
Pub Date : 2001-11-11 DOI: 10.1115/imece2001/bed-23120
Elena S. Di Martino, D. Whang, A. Redaelli, M. Makaroun, D. Vorp
The prevalence of abdominal aortic aneurysm (AAA) is growing together with population age, being 8.8% in a population above 65 years according to a recent study [1]. Deciding between elective surgical repair of AAA and watchful management is a complex issue due to the lack of reliable rupture risk indices. The maximum transverse diameter of AAA is most commonly used in clinical practice to base this decision. From a biomechanical viewpoint, AAA rupture is related to the balance between the stresses acting on the wall and strength of the wall tissue. Many different factors contribute to the stress within the aortic aneurysm wall, including the presence of intraluminal thrombus (ILT) [2–5], the local surface curvature [6] and material characteristics of the AAA wall [7], and the presence of local “stress concentrators” due to calcifications or local thinning. As regards the ILT, its role with respect to aneurysm wall stresses has given rise to many hypotheses. Some studies show that the pressure inside the thrombus is not reduced with respect to the arterial blood pressure, some, including studies from the authors, state a possible protective role [2–5]. Previously in our laboratory, a nonlinear, hyperelastic constitutive model was developed for ILT, and the parameters for which were determined through ex-vivo experimentation [8]. The purpose of this study was to investigate the reliability of using the same population-mean values of ILT constitutive parameters for estimates of wall stress distribution in all AAA. For this, we performed a parametric study in which the ELT constitutive parameters were varied within a physiological range and aortic wall stresses were evaluated.
腹主动脉瘤(AAA)的患病率随着人口年龄的增长而增长,根据最近的一项研究,在65岁以上的人群中,腹主动脉瘤(AAA)的患病率为8.8%[1]。由于缺乏可靠的破裂风险指标,决定是选择手术修复还是谨慎处理是一个复杂的问题。临床上最常用AAA的最大横径作为判断的依据。从生物力学的角度来看,AAA破裂与作用在管壁上的应力和管壁组织强度之间的平衡有关。许多不同的因素导致了主动脉瘤壁内的应力,包括腔内血栓(ILT)的存在[2-5],AAA壁的局部表面曲率[6]和材料特性[7],以及由于钙化或局部变薄导致的局部“应力集中物”的存在。至于ILT,它在动脉瘤壁应力方面的作用已经引起了许多假设。一些研究表明,血栓内的压力相对于动脉血压并没有降低,一些研究,包括作者的研究,指出了可能的保护作用[2-5]。之前在我们的实验室中,我们为ILT开发了一个非线性的超弹性本构模型,并通过离体实验确定了该模型的参数[8]。本研究的目的是研究使用相同的ILT本构参数的总体平均值来估计所有AAA壁应力分布的可靠性。为此,我们进行了一项参数研究,其中ELT本构参数在生理范围内变化,并评估了主动脉壁应力。
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引用次数: 1
Comparison of Upper and Lower Hybrid III Dummy Neck Compression Forces Under Vertical Loading 垂直载荷下上下混合型假颈压缩力的比较
Pub Date : 2001-11-11 DOI: 10.1115/imece2001/bed-23100
K. Friedman
The determination of the relationship of the upper and lower Hybrid III dummy neck transducer loads during vertical drop test loading was of interest in the present study. The anthropometric test device is a tool used in crash analysis. It is typically used for frontal or side crash analysis. It has however been used for vertical drop or rollover studies (1).
在垂直跌落试验加载过程中,确定上下混合型假颈换能器载荷的关系是本研究的重点。人体测量测试装置是一种用于碰撞分析的工具。它通常用于正面或侧面碰撞分析。然而,它已被用于垂直下降或翻转研究(1)。
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引用次数: 2
A Lumped Parameter Model for Cerebral Blood Flow Regulation 脑血流调节的集总参数模型
Pub Date : 2001-11-11 DOI: 10.1115/imece2001/bed-23138
M. Olufsen, L. Lipsitz, A. Nadim
Dynamic changes in cerebral blood flow and the associated vascular responses accompanying posture change that enable the brain to maintain perfusion during hypotensive stress are not fully understood. The aim of this work is to use a lumped parameter model of cerebral blood flow to analyze changes in key parameters (systemic and cerebrovascular resistances) during posture change from sitting to standing. Such a model sheds light on vascular adaptation to hypotensive stress, and could ultimately help determine the changes in cerebral autoregulation that occur in aging, hypertension, and other clinical conditions.
脑血流的动态变化和伴随体位变化的相关血管反应,使大脑在低血压应激时维持灌注,目前尚不完全清楚。这项工作的目的是利用脑血流的集总参数模型来分析从坐姿到站立姿势变化过程中关键参数(全身和脑血管阻力)的变化。这样的模型揭示了血管对低血压应激的适应,并可能最终帮助确定在衰老、高血压和其他临床条件下发生的大脑自动调节的变化。
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引用次数: 0
Analysis of Bending Behavior of Native Auricular and Costal Cartilage and Tissue Engineered Constructs 天然耳廓、肋软骨及组织工程化结构的弯曲行为分析
Pub Date : 2001-11-11 DOI: 10.1115/imece2001/bed-23009
R. Roy, S. Kohles, V. Zaporojan, L. Bonassar
The current literature presents many techniques for analysis of the mechanical properties of articular cartilage [1]. By comparison few techniques are available for analysis of auricular cartilage which experiences a different mechanical environment than articular cartilage. Specifically, large deflection bending is a deformation mode that is most relevant to auricular cartilage, but has not been studied thoroughly in soft tissues. The goals of this study were to: 1) apply an elasticity model to three point bending data from normal and engineered auricular and costal cartilage; and 2) use this model to determine the tensile elastic moduli.
目前的文献提出了许多技术来分析关节软骨[1]的力学性能。通过比较,很少有技术可用于耳软骨的分析,耳软骨经历不同于关节软骨的力学环境。其中,大挠度弯曲是与耳软骨最为相关的一种变形方式,但在软组织中的研究还不够深入。本研究的目的是:1)将弹性模型应用于正常和工程耳廓和肋软骨的三点弯曲数据;2)利用该模型确定拉伸弹性模量。
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引用次数: 0
Development of an Input Interface Using Ocular Potential for Handicapped Users of Health Care Supporting Computer 医疗辅助电脑残障使用者眼电位输入介面之开发
Pub Date : 2001-11-11 DOI: 10.1115/imece2001/bed-23098
F. Mizuno, A. Harada, T. Yamaguchi
Numerous attempts to adapt multimedia communication to medical care have been reported recently. It is our view that spiritual support is more important in medical care, while so-called high technology may be necessary for medical practice. Therefore, we proposed the concept of the Hyper Hospital [1–3], to offer patients a means of effective human communication during medical care. The Hyper Hospital is a medical system constructed on a computer and multimedia based-network, which patients use to participate in medical and care activities through improved communication media. It is sometimes difficult for physically handicapped patients, such as PMD (progressive muscular dystrophy), ALS (amyotrophic lateral sclerosis), and traumatic cervical injury patients, to operate a computer, because of their disabilities. Therefore, there is a serious digital divide between physically disabled patients and healthy people. To remedy this, various communication devices, such as those using winking, eye gaze, voice, and electrical biological signals (event-related potential [4–5], electrooculogram, etc.) have been proposed and tested. These are designed to enable seriously handicapped patients to use a computer without using the usual mechanical input devices, such as a keyboard, mouse, or joystick. Although an EEG (electroencephalogram) offers one source of such potential electrical biological signals, it produces a very weak electrical signal that contaminating noise makes difficult to process. On the other hand, the ocular potential generated by the dipolar potential of the eyeball has a much larger gain in potential than the EEG. Moreover, the ocular potential can be easily controlled by the user, and eye-movement ability remains largely intact, even after neurological diseases progress to a very advanced stage. Therefore, this report studied the development of an input interface for computers using an electrooculogram.
最近报道了许多将多媒体通信应用于医疗保健的尝试。我们认为精神支持在医疗中更重要,而所谓的高科技可能是医疗实践所必需的。因此,我们提出了Hyper Hospital的概念[1-3],为患者在医疗过程中提供一种有效的人际沟通手段。超级医院是建立在计算机和多媒体网络上的医疗系统,患者通过改进的通信媒体参与医疗和护理活动。身体残疾的患者,如进行性肌肉萎缩症(PMD)、肌萎缩性侧索硬化症(ALS)、外伤性颈椎损伤患者,由于残疾,有时很难操作电脑。因此,在身体残疾患者和健康人之间存在着严重的数字鸿沟。为了解决这个问题,人们提出并测试了各种通信设备,例如使用眨眼、眼睛凝视、声音和生物电信号(事件相关电位[4-5]、眼电图等)的通信设备。这些设计是为了让严重残疾的病人不用通常的机械输入设备,如键盘、鼠标或操纵杆就能使用电脑。虽然脑电图(EEG)提供了这种潜在的生物电信号的一个来源,但它产生的电信号非常微弱,污染噪音使其难以处理。另一方面,眼球偶极电位产生的眼电位比脑电图的电位增益大得多。此外,眼电位可以很容易地被使用者控制,即使在神经系统疾病进展到非常晚期时,眼动能力也基本保持不变。因此,本报告研究了使用眼电图的计算机输入接口的开发。
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引用次数: 0
Mathematical Modeling of Normal, Degenerated, and Fused Cervical Spines Using IAR’S Concept 应用IAR的概念建立正常、退变和融合颈椎的数学模型
Pub Date : 2001-11-11 DOI: 10.1115/imece2001/bed-23038
A. Meghdari, A. Bahrami
During flexion/extension, of the head-neck system, cervical spine undergoes a stepwise motion from the upper to lower regions with a specific time lag. Motion of each vertebrae is composed of a translation and a rotation with respect to lower vertebrae, which may be considered as an absolute rotation about an axis called Instantaneous Axis of Rotation (IAR). Location of this axis is different between normal, and degenerated spines. In this research intersegmental force-moments are evaluated and compared in normal, degenerated, and fused subjects employing a biomechanical model of head-neck system based on IAR’s concept and the results are presented.
在头颈系统的屈伸过程中,颈椎经历了从上到下的逐步运动,并有一定的滞后时间。每个椎骨的运动由相对于下椎骨的平移和旋转组成,这可以被认为是围绕一个称为瞬时旋转轴(IAR)的轴的绝对旋转。这个轴的位置在正常和退化的脊柱之间是不同的。在本研究中,采用基于IAR概念的头颈系统生物力学模型,评估和比较了正常,退化和融合受试者的节段间力力矩,并给出了结果。
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引用次数: 0
Contour Based Implementation of Long Bone Adaptation 基于轮廓线的长骨自适应实现
Pub Date : 2001-11-11 DOI: 10.1115/imece2001/bed-23024
M. D. Roberts, R. T. Hart
The adaptation of bone to its mechanical demands is often described as a feedback control system wherein some aspect of the tissue strain environment acts as a driving signal to initiate cellular-level formation and resorption processes on bone surfaces. While this description may be somewhat simplified, the control system view is useful for organizing ideas, experiments, and simulations of adaptation. In the past 25 years, several investigators have introduced mathematical models and (finite element-based) computer simulations of bone adaptation, using numerous candidate driving mechanical signals as proposed bone mass regulators [1]. These simulations generally use the finite element method — including the appropriate geometry, material description, and loading — to calculate the needed tissue strain parameter being considered as the specific regulation signal. Based on the adaptive response being simulated — geometric and/or material property changes — the finite element model is updated, and re-analyzed in a series of discrete time steps.
骨对其机械需求的适应通常被描述为一个反馈控制系统,其中组织应变环境的某些方面作为驱动信号启动骨表面细胞水平的形成和吸收过程。虽然这种描述可能有些简化,但控制系统的观点对于组织思想、实验和适应性模拟是有用的。在过去的25年里,一些研究者引入了骨适应的数学模型和(基于有限元的)计算机模拟,使用许多候选驱动机械信号作为拟议的骨量调节因子[1]。这些模拟通常使用有限元方法-包括适当的几何形状,材料描述和加载-来计算所需的组织应变参数,被认为是特定的调节信号。基于所模拟的自适应响应——几何和/或材料性质的变化——更新有限元模型,并在一系列离散时间步长中重新分析。
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引用次数: 0
Predicting a Power Law Between Elastic Modulus and Porosity in Cortical Bone: A Micromechanics Model 预测皮质骨弹性模量和孔隙率之间的幂律:一个微观力学模型
Pub Date : 2001-11-11 DOI: 10.1115/imece2001/bed-23032
X. N. Dong, X. Guo
Age-related changes in microstructure and composition of bone tissue are becoming increasing important as people continue to live longer. The cortical porosity increases with age in both men and women [1]. Age related increases in Haversian canal size and Haversian canal number contribute to the increasing porosity of cortical bone for the elderly men and women [2, 3]. The number of osteoclastic resorption space is also greater in the old men than in the young men [3]. The increased porosity and the higher prevalence of giant Haverian canals have a markedly negative influence on the ability of the cortical shell to withstand mechanical loads associated with a fall [4].
随着人们寿命的延长,骨组织微结构和组成与年龄相关的变化变得越来越重要。男性和女性的皮质孔隙度都随着年龄的增长而增加。年龄相关的哈弗氏管大小和哈弗氏管数量增加导致老年男性和女性皮质骨孔隙度增加[2,3]。老年男性的破骨细胞吸收空间数量也大于年轻男性。孔隙度的增加和巨大哈弗氏管的普遍存在对皮质壳承受与坠落bbb相关的机械载荷的能力有显著的负面影响。
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引用次数: 0
Numerical Analysis of Blood Flow in a Left Ventricle 左心室血流的数值分析
Pub Date : 2001-11-11 DOI: 10.1115/imece2001/bed-23113
H. Iwase, Hao Liu, S. Fujimoto, R. Himeno
We present a numerical study of dynamical blood flow in a left ventricle of human heart using Computational Fluid Dynamics (CFD). Three-dimensional shape of the left ventricle model was reconstructed using spline interpolation, based on a set of two-dimensional ultrasound echocardiogram images. Blood flow in the left ventricle was computed by solving the incompressible, unsteady Navier-Stokes equations in a manner of Finite Volume Method (FVM). In the present preliminary results the asymmetric intracardiac flow pattern is detected very similar to observed in vivo (Kilner, 2000) which shows a large vortex and a small vortex at diastole.
本文利用计算流体动力学(CFD)对人类心脏左心室血流动力学进行了数值研究。基于一组二维超声心动图图像,采用样条插值法重建左心室模型的三维形状。采用有限体积法(FVM)求解不可压缩非定常Navier-Stokes方程,计算左心室血流。在目前的初步结果中,检测到的不对称心内血流模式与在体内观察到的非常相似(Kilner, 2000),在舒张期显示一个大漩涡和一个小漩涡。
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引用次数: 0
期刊
Advances in Bioengineering
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