首页 > 最新文献

Environmental research, health : ERH最新文献

英文 中文
Demonstrating the most effective interventions to improve classroom air quality. What novel in situ tests of real-world conditions show is still missing in our guidance 展示改善课堂空气质量的最有效干预措施。我们的指南中仍然缺少对真实世界条件的新颖原位测试所显示的内容
Pub Date : 2023-07-10 DOI: 10.1088/2752-5309/ace5c9
D. Green, N. Cooper, C. D. de Silva, Prateek Bahl, Shovon Bhattacharjee, Mohamed Mahmoud Abdelkareem Mahmoud, C. Doolan, R. MacIntyre
Over 20 years ago a report commissioned by the European Commission identified air quality in schools as a public health priority. Despite this concern, little action was taken in the following two decades. Over the last two years as classrooms were increasingly recognised as hotspots for the transmission of SARS-CoV-2, renewed interest and resources have been made available in response to this issue. Questions remain, however, over how best to achieve safer classroom air. Our analysis assessed a range of in situ interventions to remove particulate matter (PM2.5) and carbon dioxide from inside a populated classroom. Our approach used saline spray and volunteers’ exhalations as our source of PM2.5 and carbon dioxide to explore the ability of high efficiency particulate air (HEPA) filters, natural ventilation and a recirculating A/C unit to remove these air pollutants which collectively provided a novel set of data. For a total window opening of 1.86 m2 for a 181.7 m3 classroom with a HEPA filter with a 703m3/hr clean air delivery rate, our results confirmed that outdoor air was needed to purge the room to reduce carbon dioxide levels that otherwise rose to >1000 ppm in 12 min. Cross and natural ventilation reduced levels of PM2.5 and carbon dioxide very effectively—in under 5 and 10 min respectively during low levels of outside PM2.5. We conclude that natural ventilation supplemented with the use of HEPA filters is the most effective way to reliably improve indoor air quality year-round, balancing the need to have easy to enact approaches to reduce the buildup of PM2.5, airborne viruses and carbon dioxide. These results highlight an important knowledge gap. Without having localised real-time outdoor air pollution sensing, evidence-based decisions cannot be made about how often, and for how long, windows can safely remain open to purge classrooms in times of poor quality outdoor air.
20多年前,欧盟委员会委托编写的一份报告将学校的空气质量确定为公共卫生的优先事项。尽管存在这种担忧,但在随后的二十年里几乎没有采取任何行动。在过去的两年里,随着教室越来越被认为是严重急性呼吸系统综合征冠状病毒2型传播的热点,人们对这一问题重新产生了兴趣,并提供了资源。然而,如何最好地实现更安全的课堂空气仍然存在问题。我们的分析评估了一系列现场干预措施,以清除人口稠密的教室内的颗粒物(PM2.5)和二氧化碳。我们的方法使用盐水喷雾和志愿者的呼气作为PM2.5和二氧化碳的来源,以探索高效微粒空气过滤器、自然通风和循环空调装置去除这些空气污染物的能力,这些共同提供了一组新的数据。对于181.7m3教室的总窗户开口1.86m2,该教室配备了703m3/hr清洁空气输送率的高效空气过滤器,我们的研究结果证实,需要室外空气来净化房间,以降低二氧化碳水平,否则二氧化碳水平将在12分钟内上升至>1000ppm。交叉通风和自然通风非常有效地降低了PM2.5和二氧化碳的水平——在室外PM2.5水平较低的情况下,分别在5分钟和10分钟内。我们得出的结论是,补充使用高效空气过滤器的自然通风是全年可靠改善室内空气质量的最有效方法,同时平衡了减少PM2.5、空气传播病毒和二氧化碳积聚的简单方法的需要。这些结果突出了一个重要的知识差距。如果没有本地化的实时室外空气污染传感,就无法做出基于证据的决定,即在室外空气质量差的时候,窗户可以安全地保持打开的频率和时间。
{"title":"Demonstrating the most effective interventions to improve classroom air quality. What novel in situ tests of real-world conditions show is still missing in our guidance","authors":"D. Green, N. Cooper, C. D. de Silva, Prateek Bahl, Shovon Bhattacharjee, Mohamed Mahmoud Abdelkareem Mahmoud, C. Doolan, R. MacIntyre","doi":"10.1088/2752-5309/ace5c9","DOIUrl":"https://doi.org/10.1088/2752-5309/ace5c9","url":null,"abstract":"Over 20 years ago a report commissioned by the European Commission identified air quality in schools as a public health priority. Despite this concern, little action was taken in the following two decades. Over the last two years as classrooms were increasingly recognised as hotspots for the transmission of SARS-CoV-2, renewed interest and resources have been made available in response to this issue. Questions remain, however, over how best to achieve safer classroom air. Our analysis assessed a range of in situ interventions to remove particulate matter (PM2.5) and carbon dioxide from inside a populated classroom. Our approach used saline spray and volunteers’ exhalations as our source of PM2.5 and carbon dioxide to explore the ability of high efficiency particulate air (HEPA) filters, natural ventilation and a recirculating A/C unit to remove these air pollutants which collectively provided a novel set of data. For a total window opening of 1.86 m2 for a 181.7 m3 classroom with a HEPA filter with a 703m3/hr clean air delivery rate, our results confirmed that outdoor air was needed to purge the room to reduce carbon dioxide levels that otherwise rose to >1000 ppm in 12 min. Cross and natural ventilation reduced levels of PM2.5 and carbon dioxide very effectively—in under 5 and 10 min respectively during low levels of outside PM2.5. We conclude that natural ventilation supplemented with the use of HEPA filters is the most effective way to reliably improve indoor air quality year-round, balancing the need to have easy to enact approaches to reduce the buildup of PM2.5, airborne viruses and carbon dioxide. These results highlight an important knowledge gap. Without having localised real-time outdoor air pollution sensing, evidence-based decisions cannot be made about how often, and for how long, windows can safely remain open to purge classrooms in times of poor quality outdoor air.","PeriodicalId":72938,"journal":{"name":"Environmental research, health : ERH","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46821011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Steam cracker facilities in the United States: operations, emissions, and sociodemographic patterns of surrounding populations 美国的蒸汽裂解装置:操作、排放和周围人口的社会人口结构模式
Pub Date : 2023-07-03 DOI: 10.1088/2752-5309/acdcb2
N. Johnson, M. Bell, Nicholas Perez, Robert Dubrow, N. Deziel
Background: Production of shale gas in the United States (US) increased more than 10-fold from 2008 to 2021, yielding greater quantities of hydrocarbon feedstocks and incentivizing expansion of petrochemical facilities. Steam crackers (SCs) convert hydrocarbon feedstocks into ethylene and propylene (the building blocks of plastics), while releasing toxic chemicals and greenhouse gases (GHGs). Analyses of environmental health and justice impacts of SCs are limited. Methods: We described SC operations, locations, and emissions, and evaluated sociodemographic characteristics of populations residing near SCs to better understand potential public health hazards and inform future studies. We summarized and described industry-reported emissions from the US Environmental Protection Agency’s Toxic Release Inventory and GHG Reporting Program. We compared population characteristics of US Census block groups ⩽5 km and >5 km from a steam cracker-containing facility (SCF) within the same county. Results: We identified 32 SCFs across five US states, with most in Texas and Louisiana. Toxic chemicals with the greatest reported cumulative air emissions in 1987–2019 were: ethylene, propylene, hydrochloric acid, benzene, n-hexane, 1,3-butadiene, ammonia, toluene, vinyl acetate, and methanol. Reported total annual GHG emissions were 4% higher in 2019 versus 2010, with total GHG emissions of >650 million metric tons (carbon dioxide equivalents) in 2010–2019. We found that 752 465 people live in census block groups ⩽5 km from an SCF, regardless of county. Compared to block groups >5 km away within the same county, block groups closer to SCFs had statistically significantly lower median incomes ($54 843 vs $67 866) and more vacant housing (15% vs 11%), and higher proportions of residents who were non-Hispanic Black (31% vs 19%) and unemployed (8% vs 6%). Conclusion: SCs emit substantial amounts of GHGs and toxic chemicals in locations with historically disadvantaged populations. Future research could further evaluate the accuracy of reported emissions, conduct monitoring in proximate communities, and assess population-level health impacts.
背景:从2008年到2021年,美国页岩气产量增长了10多倍,产生了更多的碳氢化合物原料,并激励了石化设施的扩张。蒸汽裂解器(SC)将碳氢化合物原料转化为乙烯和丙烯(塑料的组成部分),同时释放有毒化学物质和温室气体。SC对环境健康和司法影响的分析有限。方法:我们描述了SC的操作、位置和排放,并评估了居住在SC附近的人群的社会人口学特征,以更好地了解潜在的公共卫生危害,并为未来的研究提供信息。我们总结并描述了美国环境保护局有毒物质排放清单和GHG报告计划中的行业报告排放量。我们比较了同一县内距离蒸汽裂解器容纳设施(SCF)5公里和>5公里的美国人口普查区块群的人口特征。结果:我们在美国五个州发现了32个SCF,其中大部分在德克萨斯州和路易斯安那州。1987年至2019年报告的累计空气排放量最大的有毒化学品是:乙烯、丙烯、盐酸、苯、正己烷、1,3-丁二烯、氨、甲苯、乙酸乙烯酯和甲醇。与2010年相比,2019年报告的年度温室气体排放总量增加了4%,2010-2019年温室气体总排放量超过6.5亿吨(二氧化碳当量)。我们发现752 465人居住在人口普查区块群中,距离SCF 5公里,不分县。与同一县内>5公里外的街区组相比,更接近SCF的街区组的中位收入在统计上显著较低(54美元 843对67美元 866)和更多的空置住房(15%对11%),非西班牙裔黑人(31%对19%)和失业者(8%对6%)的比例更高。结论:在历史上处于不利地位的地区,SCs排放大量的温室气体和有毒化学物质。未来的研究可以进一步评估报告的排放量的准确性,在邻近社区进行监测,并评估人口水平的健康影响。
{"title":"Steam cracker facilities in the United States: operations, emissions, and sociodemographic patterns of surrounding populations","authors":"N. Johnson, M. Bell, Nicholas Perez, Robert Dubrow, N. Deziel","doi":"10.1088/2752-5309/acdcb2","DOIUrl":"https://doi.org/10.1088/2752-5309/acdcb2","url":null,"abstract":"Background: Production of shale gas in the United States (US) increased more than 10-fold from 2008 to 2021, yielding greater quantities of hydrocarbon feedstocks and incentivizing expansion of petrochemical facilities. Steam crackers (SCs) convert hydrocarbon feedstocks into ethylene and propylene (the building blocks of plastics), while releasing toxic chemicals and greenhouse gases (GHGs). Analyses of environmental health and justice impacts of SCs are limited. Methods: We described SC operations, locations, and emissions, and evaluated sociodemographic characteristics of populations residing near SCs to better understand potential public health hazards and inform future studies. We summarized and described industry-reported emissions from the US Environmental Protection Agency’s Toxic Release Inventory and GHG Reporting Program. We compared population characteristics of US Census block groups ⩽5 km and >5 km from a steam cracker-containing facility (SCF) within the same county. Results: We identified 32 SCFs across five US states, with most in Texas and Louisiana. Toxic chemicals with the greatest reported cumulative air emissions in 1987–2019 were: ethylene, propylene, hydrochloric acid, benzene, n-hexane, 1,3-butadiene, ammonia, toluene, vinyl acetate, and methanol. Reported total annual GHG emissions were 4% higher in 2019 versus 2010, with total GHG emissions of >650 million metric tons (carbon dioxide equivalents) in 2010–2019. We found that 752 465 people live in census block groups ⩽5 km from an SCF, regardless of county. Compared to block groups >5 km away within the same county, block groups closer to SCFs had statistically significantly lower median incomes ($54 843 vs $67 866) and more vacant housing (15% vs 11%), and higher proportions of residents who were non-Hispanic Black (31% vs 19%) and unemployed (8% vs 6%). Conclusion: SCs emit substantial amounts of GHGs and toxic chemicals in locations with historically disadvantaged populations. Future research could further evaluate the accuracy of reported emissions, conduct monitoring in proximate communities, and assess population-level health impacts.","PeriodicalId":72938,"journal":{"name":"Environmental research, health : ERH","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45141949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ambient air temperature and temperature variability affecting blood pressure—a repeated-measures study in Augsburg, Germany 环境空气温度和温度变化对血压的影响——德国奥格斯堡的一项重复测量研究
Pub Date : 2023-06-28 DOI: 10.1088/2752-5309/acdf10
M. Woeckel, A. Schneider, J. Cyrys, K. Wolf, C. Meisinger, M. Heier, A. Peters, S. Breitner
Ambient air temperature and temperature variability are supposed to influence blood pressure (BP); however, findings are inconsistent. We examined the effects of short-term changes in ambient temperature and temperature variability on systolic BP (SBP), diastolic BP (DBP), mean arterial pressure (MAP), and pulse pressure (PP) in a repeated-measures study. Repeated BP measurements were available for 3184 participants from the German population-based Cooperative Health Research in the Region of Augsburg (KORA) S4 survey (1999–2001) and two follow-up examinations (2006–08 and 2013–14). Daily meteorological data were obtained from fixed measurement stations including air temperature and diurnal temperature range (DTR). We used confounder-adjusted additive mixed models to examine immediate (same-day, lag 0), delayed (lag 1 to lag 4), and cumulative (up to lag 0–13) exposure effects. Decreases in air temperature were associated with increases in SBP, DBP, and MAP, while we observed no effects for PP at all. For example, a 1 °C decrease in the 14-day moving average (lag 0–13) mean air temperature was associated with a 0.54% [95% confidence interval [95%CI]: 0.41%;0.68%] increase in SBP. Furthermore, decreasing DTR was linked to increasing SBP, DBP, and MAP measures. In the sensitivity analyses, results were found to be robust. Examination of exposure–response functions according to season revealed, that associations for summer and winter can be considered linear, while we detected non-linear functions in spring and autumn. Furthermore, exposure–response functions also differed in the three different surveys. As BP levels influence the risk of cardiovascular mortality, our results show the importance of considering temperature and its variation as potential risk factors. As ongoing climate change affects temperature variability, it is important to understand how the body adapts to changing ambient temperatures.
环境空气温度和温度变异性被认为会影响血压(BP);然而,研究结果并不一致。在一项重复测量研究中,我们检查了环境温度和温度变异性的短期变化对收缩压(SBP)、舒张压(DBP)、平均动脉压(MAP)和脉压(PP)的影响。来自德国奥格斯堡地区基于人群的合作健康研究(KORA)S4调查(1999-2001年)和两次随访检查(2006-208年和2013-14年)的3184名参与者可重复测量血压。从固定的测量站获得每日气象数据,包括气温和昼夜温度范围(DTR)。我们使用混杂因素调整的加性混合模型来检验即时(当天,滞后0)、延迟(滞后1至滞后4)和累积(直至滞后0–13)暴露效应。空气温度的降低与收缩压、舒张压和MAP的增加有关,而我们观察到对PP没有任何影响。例如,14天移动平均气温下降1°C(滞后0-13)与0.54%[95%置信区间[95%CI]:0.41%有关;0.68%]增加SBP。此外,DTR的降低与SBP、DBP和MAP测量的增加有关。在敏感性分析中,结果是稳健的。根据季节对暴露-反应函数的检查表明,夏季和冬季的关联可以被认为是线性的,而我们在春季和秋季检测到了非线性函数。此外,在三项不同的调查中,暴露-反应函数也有所不同。由于血压水平影响心血管死亡的风险,我们的研究结果表明,将温度及其变化视为潜在风险因素的重要性。由于持续的气候变化会影响温度变化,了解身体如何适应不断变化的环境温度很重要。
{"title":"Ambient air temperature and temperature variability affecting blood pressure—a repeated-measures study in Augsburg, Germany","authors":"M. Woeckel, A. Schneider, J. Cyrys, K. Wolf, C. Meisinger, M. Heier, A. Peters, S. Breitner","doi":"10.1088/2752-5309/acdf10","DOIUrl":"https://doi.org/10.1088/2752-5309/acdf10","url":null,"abstract":"Ambient air temperature and temperature variability are supposed to influence blood pressure (BP); however, findings are inconsistent. We examined the effects of short-term changes in ambient temperature and temperature variability on systolic BP (SBP), diastolic BP (DBP), mean arterial pressure (MAP), and pulse pressure (PP) in a repeated-measures study. Repeated BP measurements were available for 3184 participants from the German population-based Cooperative Health Research in the Region of Augsburg (KORA) S4 survey (1999–2001) and two follow-up examinations (2006–08 and 2013–14). Daily meteorological data were obtained from fixed measurement stations including air temperature and diurnal temperature range (DTR). We used confounder-adjusted additive mixed models to examine immediate (same-day, lag 0), delayed (lag 1 to lag 4), and cumulative (up to lag 0–13) exposure effects. Decreases in air temperature were associated with increases in SBP, DBP, and MAP, while we observed no effects for PP at all. For example, a 1 °C decrease in the 14-day moving average (lag 0–13) mean air temperature was associated with a 0.54% [95% confidence interval [95%CI]: 0.41%;0.68%] increase in SBP. Furthermore, decreasing DTR was linked to increasing SBP, DBP, and MAP measures. In the sensitivity analyses, results were found to be robust. Examination of exposure–response functions according to season revealed, that associations for summer and winter can be considered linear, while we detected non-linear functions in spring and autumn. Furthermore, exposure–response functions also differed in the three different surveys. As BP levels influence the risk of cardiovascular mortality, our results show the importance of considering temperature and its variation as potential risk factors. As ongoing climate change affects temperature variability, it is important to understand how the body adapts to changing ambient temperatures.","PeriodicalId":72938,"journal":{"name":"Environmental research, health : ERH","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48685750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extreme temperature and storm exacerbations of pediatric asthma: evidence and prevention strategies 极端温度和风暴加剧儿童哮喘:证据和预防策略
Pub Date : 2023-06-26 DOI: 10.1088/2752-5309/acdf11
V. Avula, Joyce M Cheng, M. McCormack, M. Pavelack
Asthma is the most common chronic disease in children and a main cause of hospitalizations, with substantial costs to patients, families, and society. Existing disparities in asthma will likely be impacted by the increasing adverse consequences of climate change and the disproportionate impact on low-income and minority communities. Increased extreme temperatures, weather events, air pollution, and allergens linked to climate change exacerbate pediatric asthma. There is a need for greater understanding of the climate change-related risk factors specifically impacting pediatric asthma exacerbations, increased attention to health disparities, and development of strategies for prevention and management. This perspective piece describes selected research on temperature and storm-related asthma exacerbations in children and includes a discussion on possible mechanisms for weather phenomena and climate change associations, research gaps, and possible solutions related to secondary prevention (figure 1).
哮喘是儿童中最常见的慢性疾病,也是住院治疗的主要原因,给患者、家庭和社会带来了巨大的成本。气候变化日益严重的不利后果以及对低收入和少数民族社区的不成比例的影响可能会影响哮喘的现有差异。极端温度的增加、天气事件、空气污染以及与气候变化有关的过敏原加剧了儿童哮喘。有必要进一步了解气候变化相关的风险因素,特别是影响儿童哮喘恶化的因素,增加对健康差距的关注,并制定预防和管理战略。这篇透视文章描述了有关儿童温度和风暴相关哮喘加重的选定研究,并包括对天气现象和气候变化关联的可能机制、研究差距以及与二级预防相关的可能解决方案的讨论(图1)。
{"title":"Extreme temperature and storm exacerbations of pediatric asthma: evidence and prevention strategies","authors":"V. Avula, Joyce M Cheng, M. McCormack, M. Pavelack","doi":"10.1088/2752-5309/acdf11","DOIUrl":"https://doi.org/10.1088/2752-5309/acdf11","url":null,"abstract":"Asthma is the most common chronic disease in children and a main cause of hospitalizations, with substantial costs to patients, families, and society. Existing disparities in asthma will likely be impacted by the increasing adverse consequences of climate change and the disproportionate impact on low-income and minority communities. Increased extreme temperatures, weather events, air pollution, and allergens linked to climate change exacerbate pediatric asthma. There is a need for greater understanding of the climate change-related risk factors specifically impacting pediatric asthma exacerbations, increased attention to health disparities, and development of strategies for prevention and management. This perspective piece describes selected research on temperature and storm-related asthma exacerbations in children and includes a discussion on possible mechanisms for weather phenomena and climate change associations, research gaps, and possible solutions related to secondary prevention (figure 1).","PeriodicalId":72938,"journal":{"name":"Environmental research, health : ERH","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43945859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Early-life oxidative stress due to air pollution. A scoping review focusing on identifying potential ‘-OMICS’ biomarkers from body fluids 早期由于空气污染造成的氧化应激。专注于从体液中识别潜在“-OMICS”生物标志物的范围界定综述
Pub Date : 2023-06-22 DOI: 10.1088/2752-5309/acdd18
J. Coumans, S. Al Jaaidi
Exposure to air pollution (AP) is inevitable in daily life and an increasing number of epidemiological studies have reported that exposure to ambient particulate matter (PM) is associated with adverse health outcomes. Intrauterine, childhood, and adolescence are vulnerable periods, during which PM exposure can cause molecular changes, potentially leading to changes in metabolism and development. PM-induced oxidative stress is the underlying mechanism. Biomarkers can be used as illustrative measures of PM exposure to facilitate the assessment of potential health effects and provide a better understanding of the underlying mechanisms. The purpose of this scoping review is to report -OMICS biomarkers found in body fluids that are primarily related to oxidative stress and are already used to evaluate ambient AP exposure, as well as to identify knowledge gaps. Web of Science, PubMed, and Scopus databases were independently searched for all studies published between January 2013 and December 2022 that reported on -OMICS signature changes during pregnancy, childhood, and adolescence. Of the initial 757 articles, 36 met our inclusion criteria and reported on genomic, epigenomic, transcriptomic, proteomic, lipidomic, and metabolomic biomarkers. The findings of this scoping review indicate that exposure to various ambient pollutants in early life can cause oxidative stress. Integrating biomarkers from top-down -OMICS studies in an epidemiological context may provide a clear picture of the biomarker selection process to establish a causal relationship between PM exposure and disease pathogenesis. This knowledge could lead to the conceptualization and subsequent development of novel preventative strategies.
暴露于空气污染(AP)在日常生活中是不可避免的,越来越多的流行病学研究报告称,暴露于环境颗粒物(PM)与不良健康后果有关。宫内、儿童期和青春期是易受伤害的时期,在这段时间内,PM暴露会引起分子变化,可能导致代谢和发育的变化。PM诱导的氧化应激是其潜在机制。生物标志物可以用作PM暴露的说明性测量,以促进对潜在健康影响的评估,并更好地了解潜在机制。本范围审查的目的是报告体液中发现的OMICS生物标志物,这些生物标志物主要与氧化应激有关,并已用于评估环境AP暴露,以及确定知识差距。Web of Science、PubMed和Scopus数据库独立搜索了2013年1月至2022年12月期间发表的所有研究,这些研究报告了怀孕、儿童和青少年期间-OMICS特征的变化。在最初的757篇文章中,有36篇符合我们的纳入标准,并报道了基因组、表观基因组、转录组、蛋白质组、脂质组和代谢组生物标志物。这项范围审查的结果表明,在早期接触各种环境污染物会导致氧化应激。将自上而下的OMICS研究中的生物标志物整合到流行病学背景中,可以清楚地了解生物标志物的选择过程,从而建立PM暴露与疾病发病机制之间的因果关系。这些知识可能会导致新的预防策略的概念化和随后的发展。
{"title":"Early-life oxidative stress due to air pollution. A scoping review focusing on identifying potential ‘-OMICS’ biomarkers from body fluids","authors":"J. Coumans, S. Al Jaaidi","doi":"10.1088/2752-5309/acdd18","DOIUrl":"https://doi.org/10.1088/2752-5309/acdd18","url":null,"abstract":"Exposure to air pollution (AP) is inevitable in daily life and an increasing number of epidemiological studies have reported that exposure to ambient particulate matter (PM) is associated with adverse health outcomes. Intrauterine, childhood, and adolescence are vulnerable periods, during which PM exposure can cause molecular changes, potentially leading to changes in metabolism and development. PM-induced oxidative stress is the underlying mechanism. Biomarkers can be used as illustrative measures of PM exposure to facilitate the assessment of potential health effects and provide a better understanding of the underlying mechanisms. The purpose of this scoping review is to report -OMICS biomarkers found in body fluids that are primarily related to oxidative stress and are already used to evaluate ambient AP exposure, as well as to identify knowledge gaps. Web of Science, PubMed, and Scopus databases were independently searched for all studies published between January 2013 and December 2022 that reported on -OMICS signature changes during pregnancy, childhood, and adolescence. Of the initial 757 articles, 36 met our inclusion criteria and reported on genomic, epigenomic, transcriptomic, proteomic, lipidomic, and metabolomic biomarkers. The findings of this scoping review indicate that exposure to various ambient pollutants in early life can cause oxidative stress. Integrating biomarkers from top-down -OMICS studies in an epidemiological context may provide a clear picture of the biomarker selection process to establish a causal relationship between PM exposure and disease pathogenesis. This knowledge could lead to the conceptualization and subsequent development of novel preventative strategies.","PeriodicalId":72938,"journal":{"name":"Environmental research, health : ERH","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42214627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidemiological evidence on drinking water salinity and blood pressure: a scoping review 饮用水盐度和血压的流行病学证据:范围综述
Pub Date : 2023-06-21 DOI: 10.1088/2752-5309/ace076
Christina Xeni, R. Oliva, Farjana Jahan, R. Iqbal, A. Naser, Md. Mahbubur Rahman, L. Fleming, Matthew O'Madigan Gribble, K. Makris
In addition to diet, drinking water can be an important contributor to the total body burden of salts. Water salinity (defined as the amount of dissolved salts in a body of water) has been associated with adverse health effects. We mapped the current research on drinking water salinity and its effects on blood pressure (BP). We aimed to identify knowledge gaps in the methodology and tools used in the epidemiological literature to address water salinity effects on BP. We performed a scoping review of epidemiological studies by searching PubMed and Web of Science databases from 1980 to 2022. Reviews, study comparisons, meta-analyses, commentaries, viewpoints, correspondence, protocols, studies in clinical settings, animal or in vitro studies, or not in English, were excluded. Epidemiologic studies including systolic/diastolic BP and/or the risk of hypertension as the main health outcome and drinking water salts (sodium, potassium, calcium, magnesium, including electrical conductivity and total dissolved solids) as the main exposures were included. After screening 246 articles, 29 articles were retained. Most studies were conducted in Bangladesh and USA (n = 9 and n = 9, respectively). The majority of studies were cross-sectional (n = 18; 62%). The study populations were adults (55%) or children (35%) or both (10%). Only eight (28%) studies did not collect urine samples and only three studies (10%) did not record participant BP. About half of the studies (n = 15, 52%) reported a positive significant (p < 0.05) association between salts in drinking water and higher BP and/or risk of hypertension; while 24% and 24% reported non-significant (p > 0.05) and significant (p < 0.05) negative associations (with lower BP mainly attributed to higher Mg, Ca, and K (rather than Na) levels in drinking water). More longitudinal studies are warranted to investigate the impact of drinking water salinization on cardiovascular health and risk of hypertension. Under a changing climate, this may be particularly important for coastal populations, as sea level rise in combination with the overexploitation of groundwater would differentially perturb the salinity of their drinking water supplies.
除了饮食外,饮用水也是造成人体盐分总量的重要因素。水的盐度(定义为水体中溶解盐的数量)与不利的健康影响有关。我们绘制了饮用水盐度及其对血压影响的研究现状。我们的目的是确定流行病学文献中用于解决水盐度对BP影响的方法和工具的知识差距。我们通过检索PubMed和Web of Science数据库对1980年至2022年的流行病学研究进行了范围审查。综述、研究比较、荟萃分析、评论、观点、通信、协议、临床研究、动物或体外研究或非英文研究均被排除在外。流行病学研究包括收缩压/舒张压和/或高血压风险作为主要健康结果,饮用水盐(钠、钾、钙、镁,包括电导率和总溶解固体)作为主要暴露。筛选246篇,保留29篇。大多数研究在孟加拉国和美国进行(分别为n = 9和n = 9)。大多数研究是横断面的(n = 18;62%)。研究人群为成人(55%)或儿童(35%)或两者都有(10%)。只有8项(28%)研究没有收集尿液样本,只有3项(10%)研究没有记录参与者的血压。大约一半的研究(n = 15,52 %)报告了饮用水中的盐与血压升高和/或高血压风险之间的显著正相关(p < 0.05);24%和24%报告无显著(p < 0.05)和显著(p < 0.05)负相关(较低的血压主要归因于饮用水中较高的Mg, Ca和K(而不是Na)水平)。需要更多的纵向研究来调查饮用水盐碱化对心血管健康和高血压风险的影响。在气候变化的情况下,这对沿海地区的居民来说可能尤其重要,因为海平面上升加上地下水的过度开采将不同程度地扰乱他们饮用水供应的盐度。
{"title":"Epidemiological evidence on drinking water salinity and blood pressure: a scoping review","authors":"Christina Xeni, R. Oliva, Farjana Jahan, R. Iqbal, A. Naser, Md. Mahbubur Rahman, L. Fleming, Matthew O'Madigan Gribble, K. Makris","doi":"10.1088/2752-5309/ace076","DOIUrl":"https://doi.org/10.1088/2752-5309/ace076","url":null,"abstract":"In addition to diet, drinking water can be an important contributor to the total body burden of salts. Water salinity (defined as the amount of dissolved salts in a body of water) has been associated with adverse health effects. We mapped the current research on drinking water salinity and its effects on blood pressure (BP). We aimed to identify knowledge gaps in the methodology and tools used in the epidemiological literature to address water salinity effects on BP. We performed a scoping review of epidemiological studies by searching PubMed and Web of Science databases from 1980 to 2022. Reviews, study comparisons, meta-analyses, commentaries, viewpoints, correspondence, protocols, studies in clinical settings, animal or in vitro studies, or not in English, were excluded. Epidemiologic studies including systolic/diastolic BP and/or the risk of hypertension as the main health outcome and drinking water salts (sodium, potassium, calcium, magnesium, including electrical conductivity and total dissolved solids) as the main exposures were included. After screening 246 articles, 29 articles were retained. Most studies were conducted in Bangladesh and USA (n = 9 and n = 9, respectively). The majority of studies were cross-sectional (n = 18; 62%). The study populations were adults (55%) or children (35%) or both (10%). Only eight (28%) studies did not collect urine samples and only three studies (10%) did not record participant BP. About half of the studies (n = 15, 52%) reported a positive significant (p < 0.05) association between salts in drinking water and higher BP and/or risk of hypertension; while 24% and 24% reported non-significant (p > 0.05) and significant (p < 0.05) negative associations (with lower BP mainly attributed to higher Mg, Ca, and K (rather than Na) levels in drinking water). More longitudinal studies are warranted to investigate the impact of drinking water salinization on cardiovascular health and risk of hypertension. Under a changing climate, this may be particularly important for coastal populations, as sea level rise in combination with the overexploitation of groundwater would differentially perturb the salinity of their drinking water supplies.","PeriodicalId":72938,"journal":{"name":"Environmental research, health : ERH","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"61193509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Personal air pollution exposure and metals in the nasal epithelial lining fluid of COPD patients. 慢性阻塞性肺病患者个人空气污染暴露与鼻上皮内液中的金属
Pub Date : 2023-06-01 Epub Date: 2023-03-01 DOI: 10.1088/2752-5309/acbbe5
Hilary L Zetlen, Anna Stanley Lee, Lina Nurhussien, Wendy Sun, Choong-Min Kang, Antonella Zanobetti, Mary B Rice

Sampling of the nasal epithelial lining fluid is a potential method to assess exposure to air pollution within the respiratory tract among high risk populations. We investigated associations of short- and long-term particulate matter exposure (PM) and pollution-related metals in the nasal fluid of people with chronic obstructive pulmonary disease (COPD). This study included 20 participants with moderate-to-severe COPD from a larger study who measured long-term personal exposure to PM2.5 using portable air monitors and short-term PM2.5 and black carbon (BC) using in-home samplers for the seven days preceding nasal fluid collection. Nasal fluid was sampled from both nares by nasosorption, and inductively coupled plasma mass spectrometry was used to determine the concentration of metals with major airborne sources. Correlations of selected elements (Fe, Ba, Ni, Pb, V, Zn, Cu) were determined within the nasal fluid. Associations between personal long-term PM2.5 and seven day home PM2.5 and BC exposure and nasal fluid metal concentrations were determined by linear regression. Within nasal fluid samples, concentrations of vanadium and nickel (r = 0.8) and lead and zinc (r = 0.7) were correlated. Seven day and long-term PM2.5 exposure were both associated with higher levels of copper, lead, and vanadium in the nasal fluid. BC exposure was associated with higher levels of nickel in the nasal fluid. Levels of certain metals in the nasal fluid may serve as biomarkers of air pollution exposure in the upper respiratory tract.

鼻腔上皮衬里液取样是评估高危人群呼吸道内空气污染暴露情况的一种潜在方法。我们调查了慢性阻塞性肺病(COPD)患者鼻液中短期和长期颗粒物暴露(PM)与污染相关金属的关系。这项研究包括20名来自一项大型研究的中重度COPD参与者,他们使用便携式空气监测仪测量了个人长期接触PM2.5的情况,并使用家庭采样器测量了在鼻液采集前七天的短期PM2.5和黑碳(BC)。通过鼻吸附法从两个鼻孔取样,并使用电感耦合等离子体质谱法测定主要空气来源的金属浓度。在鼻液中测定所选元素(Fe、Ba、Ni、Pb、V、Zn、Cu)的相关性。通过线性回归确定个人长期PM2.5和七天家庭PM2.5、BC暴露和鼻腔液体金属浓度之间的相关性。在鼻液样本中,钒和镍的浓度(r=0.8)以及铅和锌的浓度(r=0.7)是相关的。七天和长期接触PM2.5都与鼻腔中铜、铅和钒含量较高有关。BC暴露与鼻液中镍含量较高有关。鼻腔液体中某些金属的水平可以作为上呼吸道空气污染暴露的生物标志物。
{"title":"Personal air pollution exposure and metals in the nasal epithelial lining fluid of COPD patients.","authors":"Hilary L Zetlen, Anna Stanley Lee, Lina Nurhussien, Wendy Sun, Choong-Min Kang, Antonella Zanobetti, Mary B Rice","doi":"10.1088/2752-5309/acbbe5","DOIUrl":"10.1088/2752-5309/acbbe5","url":null,"abstract":"<p><p>Sampling of the nasal epithelial lining fluid is a potential method to assess exposure to air pollution within the respiratory tract among high risk populations. We investigated associations of short- and long-term particulate matter exposure (PM) and pollution-related metals in the nasal fluid of people with chronic obstructive pulmonary disease (COPD). This study included 20 participants with moderate-to-severe COPD from a larger study who measured long-term personal exposure to PM<sub>2.5</sub> using portable air monitors and short-term PM<sub>2.5</sub> and black carbon (BC) using in-home samplers for the seven days preceding nasal fluid collection. Nasal fluid was sampled from both nares by nasosorption, and inductively coupled plasma mass spectrometry was used to determine the concentration of metals with major airborne sources. Correlations of selected elements (Fe, Ba, Ni, Pb, V, Zn, Cu) were determined within the nasal fluid. Associations between personal long-term PM<sub>2.5</sub> and seven day home PM<sub>2.5</sub> and BC exposure and nasal fluid metal concentrations were determined by linear regression. Within nasal fluid samples, concentrations of vanadium and nickel (<i>r</i> = 0.8) and lead and zinc (<i>r</i> = 0.7) were correlated. Seven day and long-term PM<sub>2.5</sub> exposure were both associated with higher levels of copper, lead, and vanadium in the nasal fluid. BC exposure was associated with higher levels of nickel in the nasal fluid. Levels of certain metals in the nasal fluid may serve as biomarkers of air pollution exposure in the upper respiratory tract.</p>","PeriodicalId":72938,"journal":{"name":"Environmental research, health : ERH","volume":"1 2","pages":"021002"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972880/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9304547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
After the fire: A qualitative study of the role of long-term recovery organizations in addressing rural communities' post-wildfire needs. 火灾之后:关于长期恢复组织在满足农村社区野火后需求方面作用的定性研究。
Pub Date : 2023-06-01 Epub Date: 2023-05-30 DOI: 10.1088/2752-5309/acd2f7
Kathleen Moloney, Jamie Vickery, Jeremy Hess, Nicole Errett

U.S. wildfire activity has increased over the past several decades, disrupting the systems and infrastructure that support community health and resilience. As the cumulative burden of wildfire damage is projected to increase, understanding an effective community recovery process is critically important. Through qualitative interviews with leaders of long-term recovery organizations (LTROs), a key component of wildfire recovery, we explored barriers and facilitators to LTROs' ability to support post-wildfire needs among rural communities. Between February-May 2022, we conducted surveys and semi-structured interviews with 18 leaders from six LTROs serving rural communities in Washington, Oregon, and California impacted by wildfires between 2015-2020. The Robert Wood Johnson Foundation's Culture of Health Framework informed the semi-structured interview guide and a priori codebook, to examine LTROs' ability to address post-wildfire community needs from a health equity perspective. Additional codes were added through an inductive approach, and emerging themes were identified. Our findings indicate that LTROs face many barriers in addressing community needs post-wildfire, including the policies governing access to and the slow arrival of recovery resources, the intertwined nature of community economic health and built environment restoration, and the challenge of forming a functional LTRO structure. However, participants also identified facilitators of LTROs' work, including the ability of LTROs and their government partners to adapt policies and procedures, and close collaboration with other community organizations. Factors both internal and external to the community and LTROs' organizational characteristics influence their ability to address community needs, essential to health, post-wildfire. This study's findings suggest the need for policy improvements to promote more equitable recovery resource access, that economic recovery should be a core LTRO function, and that recovery planning should be incorporated into community disaster preparedness activities. Future research should focus on LTROs' role in other contexts and in response to other disasters.

过去几十年来,美国的野火活动有所增加,破坏了支持社区健康和恢复能力的系统和基础设施。预计野火造成的累积损失还会增加,因此了解有效的社区恢复过程至关重要。长期恢复组织(LTROs)是野火恢复的关键组成部分,通过对长期恢复组织领导人的定性访谈,我们探讨了长期恢复组织支持农村社区野火后需求的能力所面临的障碍和促进因素。2022 年 2 月至 5 月间,我们对来自华盛顿州、俄勒冈州和加利福尼亚州的六个长期恢复组织的 18 名领导者进行了调查和半结构化访谈,这些组织在 2015-2020 年间为受野火影响的农村社区提供服务。罗伯特-伍德-约翰逊基金会的 "健康文化框架 "为半结构式访谈指南和先验代码手册提供了参考,以考察 LTROs 从健康公平角度满足野火后社区需求的能力。通过归纳法增加了其他代码,并确定了新出现的主题。我们的研究结果表明,土地退化评估组织在解决野火后社区需求方面面临着许多障碍,包括获取恢复资源的政策和恢复资源的缓慢到达、社区经济健康和建筑环境恢复的相互交织性质,以及形成一个功能性土地退化评估组织结构所面临的挑战。不过,与会者也指出了促进 LTRO 工作的因素,包括 LTRO 及其政府合作伙伴调整政策和程序的能力,以及与其他社区组织的密切合作。社区内部和外部的因素以及 LTROs 的组织特征都影响着他们在野火后满足社区需求的能力,而这些需求对健康至关重要。本研究的结果表明,需要改进政策以促进更公平的恢复资源获取,经济恢复应成为 LTRO 的核心职能,恢复规划应纳入社区备灾活动。未来的研究应重点关注 LTRO 在其他情况下和应对其他灾害时的作用。
{"title":"After the fire: A qualitative study of the role of long-term recovery organizations in addressing rural communities' post-wildfire needs.","authors":"Kathleen Moloney, Jamie Vickery, Jeremy Hess, Nicole Errett","doi":"10.1088/2752-5309/acd2f7","DOIUrl":"10.1088/2752-5309/acd2f7","url":null,"abstract":"<p><p>U.S. wildfire activity has increased over the past several decades, disrupting the systems and infrastructure that support community health and resilience. As the cumulative burden of wildfire damage is projected to increase, understanding an effective community recovery process is critically important. Through qualitative interviews with leaders of long-term recovery organizations (LTROs), a key component of wildfire recovery, we explored barriers and facilitators to LTROs' ability to support post-wildfire needs among rural communities. Between February-May 2022, we conducted surveys and semi-structured interviews with 18 leaders from six LTROs serving rural communities in Washington, Oregon, and California impacted by wildfires between 2015-2020. The Robert Wood Johnson Foundation's Culture of Health Framework informed the semi-structured interview guide and <i>a priori</i> codebook, to examine LTROs' ability to address post-wildfire community needs from a health equity perspective. Additional codes were added through an inductive approach, and emerging themes were identified. Our findings indicate that LTROs face many barriers in addressing community needs post-wildfire, including the policies governing access to and the slow arrival of recovery resources, the intertwined nature of community economic health and built environment restoration, and the challenge of forming a functional LTRO structure. However, participants also identified facilitators of LTROs' work, including the ability of LTROs and their government partners to adapt policies and procedures, and close collaboration with other community organizations. Factors both internal and external to the community and LTROs' organizational characteristics influence their ability to address community needs, essential to health, post-wildfire. This study's findings suggest the need for policy improvements to promote more equitable recovery resource access, that economic recovery should be a core LTRO function, and that recovery planning should be incorporated into community disaster preparedness activities. Future research should focus on LTROs' role in other contexts and in response to other disasters.</p>","PeriodicalId":72938,"journal":{"name":"Environmental research, health : ERH","volume":"1 2","pages":"021009"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10227461/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9565469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Air quality and health co-benefits of climate change mitigation and adaptation actions by 2030: an interdisciplinary modeling study in Ahmedabad, India. 到 2030 年减缓和适应气候变化行动的空气质量和健康共同效益:印度艾哈迈达巴德的跨学科建模研究。
Pub Date : 2023-06-01 Epub Date: 2023-03-01 DOI: 10.1088/2752-5309/aca7d8
Vijay S Limaye, Akhilesh Magal, Jaykumar Joshi, Sujit Maji, Priya Dutta, Prashant Rajput, Shyam Pingle, Prima Madan, Polash Mukerjee, Shahana Bano, Gufran Beig, Dileep Mavalankar, Anjali Jaiswal, Kim Knowlton

Climate change-driven temperature increases worsen air quality in places where coal combustion powers electricity for air conditioning. Climate solutions that substitute clean and renewable energy in place of polluting coal and promote adaptation to warming through reflective cool roofs can reduce cooling energy demand in buildings, lower power sector carbon emissions, and improve air quality and health. We investigate the air quality and health co-benefits of climate solutions in Ahmedabad, India-a city where air pollution levels exceed national health-based standards-through an interdisciplinary modeling approach. Using a 2018 baseline, we quantify changes in fine particulate matter (PM2.5) air pollution and all-cause mortality in 2030 from increasing renewable energy use (mitigation) and expanding Ahmedabad's cool roofs heat resilience program (adaptation). We apply local demographic and health data and compare a 2030 mitigation and adaptation (M&A) scenario to a 2030 business-as-usual (BAU) scenario (without climate change response actions), each relative to 2018 pollution levels. We estimate that the 2030 BAU scenario results in an increase of PM2.5 air pollution of 4.13 µg m-3 from 2018 compared to a 0.11 µg m-3 decline from 2018 under the 2030 M&A scenario. Reduced PM2.5 air pollution under 2030 M&A results in 1216-1414 fewer premature all-cause deaths annually compared to 2030 BAU. Achievement of National Clean Air Programme, National Ambient Air Quality Standards, or World Health Organization annual PM2.5 Air Quality Guideline targets in 2030 results in up to 6510, 9047, or 17 369 fewer annual deaths, respectively, relative to 2030 BAU. This comprehensive modeling method is adaptable to estimate local air quality and health co-benefits in other settings by integrating climate, energy, cooling, land cover, air pollution, and health data. Our findings demonstrate that city-level climate change response policies can achieve substantial air quality and health co-benefits. Such work can inform public discourse on the near-term health benefits of mitigation and adaptation.

在燃煤为空调提供电力的地方,气候变化导致的气温升高使空气质量恶化。用清洁和可再生能源替代污染严重的煤炭,并通过反光凉爽屋顶促进适应气候变暖的气候解决方案,可以减少建筑物的制冷能源需求,降低电力部门的碳排放,改善空气质量和健康状况。印度艾哈迈达巴德是一座空气污染水平超过国家健康标准的城市,我们通过跨学科建模方法研究了气候解决方案对该市空气质量和健康的共同效益。以 2018 年为基线,我们量化了 2030 年细微颗粒物(PM2.5)空气污染和全因死亡率的变化,这些变化来自增加可再生能源的使用(减缓)和扩大艾哈迈达巴德的凉爽屋顶抗热计划(适应)。我们应用了当地的人口和健康数据,并比较了 2030 年减缓和适应(M&A)情景与 2030 年一切照旧(BAU)情景(无气候变化应对措施),每种情景都相对于 2018 年的污染水平。我们估计,2030 年 "一切照旧 "情景会导致 PM2.5 空气污染比 2018 年增加 4.13 µg m-3,而在 2030 年减缓和适应情景下,PM2.5 空气污染比 2018 年下降 0.11 µg m-3。与 2030 年 BAU 相比,2030 年 M&A 情景下 PM2.5 空气污染的减少导致每年因各种原因过早死亡的人数减少 1216-1414 人。与 2030 年 BAU 相比,2030 年实现国家清洁空气计划、国家环境空气质量标准或世界卫生组织 PM2.5 年度空气质量指导目标可分别减少 6510、9047 或 17 369 例死亡。通过整合气候、能源、冷却、土地覆盖、空气污染和健康数据,这种综合建模方法可用于估算其他环境下的当地空气质量和健康共同效益。我们的研究结果表明,城市一级的气候变化应对政策可以实现可观的空气质量和健康共同效益。这些工作可以为公众讨论减缓和适应气候变化的近期健康效益提供信息。
{"title":"Air quality and health co-benefits of climate change mitigation and adaptation actions by 2030: an interdisciplinary modeling study in Ahmedabad, India.","authors":"Vijay S Limaye, Akhilesh Magal, Jaykumar Joshi, Sujit Maji, Priya Dutta, Prashant Rajput, Shyam Pingle, Prima Madan, Polash Mukerjee, Shahana Bano, Gufran Beig, Dileep Mavalankar, Anjali Jaiswal, Kim Knowlton","doi":"10.1088/2752-5309/aca7d8","DOIUrl":"10.1088/2752-5309/aca7d8","url":null,"abstract":"<p><p>Climate change-driven temperature increases worsen air quality in places where coal combustion powers electricity for air conditioning. Climate solutions that substitute clean and renewable energy in place of polluting coal and promote adaptation to warming through reflective cool roofs can reduce cooling energy demand in buildings, lower power sector carbon emissions, and improve air quality and health. We investigate the air quality and health co-benefits of climate solutions in Ahmedabad, India-a city where air pollution levels exceed national health-based standards-through an interdisciplinary modeling approach. Using a 2018 baseline, we quantify changes in fine particulate matter (PM<sub>2.5</sub>) air pollution and all-cause mortality in 2030 from increasing renewable energy use (mitigation) and expanding Ahmedabad's cool roofs heat resilience program (adaptation). We apply local demographic and health data and compare a 2030 mitigation and adaptation (M&A) scenario to a 2030 business-as-usual (BAU) scenario (without climate change response actions), each relative to 2018 pollution levels. We estimate that the 2030 BAU scenario results in an increase of PM<sub>2.5</sub> air pollution of 4.13 <i>µ</i>g m<sup>-3</sup> from 2018 compared to a 0.11 <i>µ</i>g m<sup>-3</sup> decline from 2018 under the 2030 M&A scenario. Reduced PM<sub>2.5</sub> air pollution under 2030 M&A results in 1216-1414 fewer premature all-cause deaths annually compared to 2030 BAU. Achievement of National Clean Air Programme, National Ambient Air Quality Standards, or World Health Organization annual PM<sub>2.5</sub> Air Quality Guideline targets in 2030 results in up to 6510, 9047, or 17 369 fewer annual deaths, respectively, relative to 2030 BAU. This comprehensive modeling method is adaptable to estimate local air quality and health co-benefits in other settings by integrating climate, energy, cooling, land cover, air pollution, and health data. Our findings demonstrate that city-level climate change response policies can achieve substantial air quality and health co-benefits. Such work can inform public discourse on the near-term health benefits of mitigation and adaptation.</p>","PeriodicalId":72938,"journal":{"name":"Environmental research, health : ERH","volume":"1 2","pages":"021003"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9975964/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10853656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring vulnerability to heat and cold across urban and rural populations in Switzerland. 探索瑞士城市和农村人口易受冷热影响的情况。
Pub Date : 2023-06-01 Epub Date: 2023-02-14 DOI: 10.1088/2752-5309/acab78
Evan de Schrijver, Dominic Royé, Antonio Gasparrini, Oscar H Franco, Ana M Vicedo-Cabrera

Heat- and cold-related mortality risks are highly variable across different geographies, suggesting a differential distribution of vulnerability factors between and within countries, which could partly be driven by urban-to-rural disparities. Identifying these drivers of risk is crucial to characterize local vulnerability and design tailored public health interventions to improve adaptation of populations to climate change. We aimed to assess how heat- and cold-mortality risks change across urban, peri-urban and rural areas in Switzerland and to identify and compare the factors associated with increased vulnerability within and between different area typologies. We estimated the heat- and cold-related mortality association using the case time-series design and distributed lag non-linear models over daily mean temperature and all-cause mortality series between 1990-2017 in each municipality in Switzerland. Then, through multivariate meta-regression, we derived pooled heat and cold-mortality associations by typology (i.e. urban/rural/peri-urban) and assessed potential vulnerability factors among a wealth of demographic, socioeconomic, topographic, climatic, land use and other environmental data. Urban clusters reported larger pooled heat-related mortality risk (at 99th percentile, vs. temperature of minimum mortality (MMT)) (relative risk=1.17(95%CI:1.10;1.24, vs peri-urban 1.03(1.00;1.06), and rural 1.03 (0.99;1.08)), but similar cold-mortality risk (at 1st percentile, vs. MMT) (1.35(1.28;1.43), vs rural 1.28(1.14;1.44) and peri-urban 1.39 (1.27-1.53)) clusters. We found different sets of vulnerability factors explaining the differential risk patterns across typologies. In urban clusters, mainly environmental factors (i.e. PM2.5) drove differences in heat-mortality association, while for peri-urban/rural clusters socio-economic variables were also important. For cold, socio-economic variables drove changes in vulnerability across all typologies, while environmental factors and ageing were other important drivers of larger vulnerability in peri-urban/rural clusters, with heterogeneity in the direction of the association. Our findings suggest that urban populations in Switzerland may be more vulnerable to heat, compared to rural locations, and different sets of vulnerability factors may drive these associations in each typology. Thus, future public health adaptation strategies should consider local and more tailored interventions rather than a one-size fits all approach. size fits all approach.

与热和冷相关的死亡风险在不同地理区域之间存在很大差异,这表明国家之间和国家内部的脆弱性因素分布不同,其部分原因可能是城市与农村之间的差异。确定这些风险驱动因素对于描述当地的脆弱性和设计有针对性的公共卫生干预措施以改善人口对气候变化的适应至关重要。我们的目标是评估瑞士城市、城郊和农村地区的高温和严寒死亡风险是如何变化的,并识别和比较不同地区类型内部和之间与脆弱性增加相关的因素。我们采用病例时间序列设计和分布式滞后非线性模型,对 1990-2017 年间瑞士各城市的日平均气温和全因死亡率序列进行了热与冷相关死亡率的估算。然后,通过多元元回归,我们得出了按类型(即城市/农村/城郊)划分的集合高温和严寒死亡率关联,并评估了大量人口、社会经济、地形、气候、土地利用和其他环境数据中的潜在脆弱性因素。城市群报告了更大的与热相关的集合死亡风险(第 99 百分位数,与最低死亡温度(MMT)相比)(相对风险=1.17(95%CI:1.10;1.24, vs 城郊为 1.03(1.00;1.06), 农村为 1.03 (0.99;1.08) ),但与寒冷相关死亡风险(第 1 百分位数,与最低死亡温度相比)相似(1.35(1.28;1.43), vs 农村为 1.28(1.14;1.44), 城郊为 1.39 (1.27-1.53))。我们发现不同的脆弱性因素可以解释不同类型的风险模式。在城市群中,主要是环境因素(即 PM2.5)导致了高温与死亡之间的关联差异,而在城郊/农村群中,社会经济变量也很重要。就寒冷而言,社会经济变量驱动了所有类型的脆弱性变化,而环境因素和老龄化则是城郊/农村集群脆弱性增加的其他重要驱动因素,但两者的关联方向存在差异。我们的研究结果表明,与农村地区相比,瑞士的城市人口可能更容易受到高温的影响,而在每种类型中,不同的脆弱性因素可能会驱动这些关联。因此,未来的公共卫生适应战略应考虑因地制宜的干预措施,而不是一刀切。
{"title":"Exploring vulnerability to heat and cold across urban and rural populations in Switzerland.","authors":"Evan de Schrijver, Dominic Royé, Antonio Gasparrini, Oscar H Franco, Ana M Vicedo-Cabrera","doi":"10.1088/2752-5309/acab78","DOIUrl":"10.1088/2752-5309/acab78","url":null,"abstract":"<p><p>Heat- and cold-related mortality risks are highly variable across different geographies, suggesting a differential distribution of vulnerability factors between and within countries, which could partly be driven by urban-to-rural disparities. Identifying these drivers of risk is crucial to characterize local vulnerability and design tailored public health interventions to improve adaptation of populations to climate change. We aimed to assess how heat- and cold-mortality risks change across urban, peri-urban and rural areas in Switzerland and to identify and compare the factors associated with increased vulnerability within and between different area typologies. We estimated the heat- and cold-related mortality association using the case time-series design and distributed lag non-linear models over daily mean temperature and all-cause mortality series between 1990-2017 in each municipality in Switzerland. Then, through multivariate meta-regression, we derived pooled heat and cold-mortality associations by typology (i.e. urban/rural/peri-urban) and assessed potential vulnerability factors among a wealth of demographic, socioeconomic, topographic, climatic, land use and other environmental data. Urban clusters reported larger pooled heat-related mortality risk (at 99th percentile, vs. temperature of minimum mortality (MMT)) (relative risk=1.17(95%CI:1.10;1.24, vs peri-urban 1.03(1.00;1.06), and rural 1.03 (0.99;1.08)), but similar cold-mortality risk (at 1st percentile, vs. MMT) (1.35(1.28;1.43), vs rural 1.28(1.14;1.44) and peri-urban 1.39 (1.27-1.53)) clusters. We found different sets of vulnerability factors explaining the differential risk patterns across typologies. In urban clusters, mainly environmental factors (i.e. PM<sub>2.5</sub>) drove differences in heat-mortality association, while for peri-urban/rural clusters socio-economic variables were also important. For cold, socio-economic variables drove changes in vulnerability across all typologies, while environmental factors and ageing were other important drivers of larger vulnerability in peri-urban/rural clusters, with heterogeneity in the direction of the association. Our findings suggest that urban populations in Switzerland may be more vulnerable to heat, compared to rural locations, and different sets of vulnerability factors may drive these associations in each typology. Thus, future public health adaptation strategies should consider local and more tailored interventions rather than a one-size fits all approach. size fits all approach.</p>","PeriodicalId":72938,"journal":{"name":"Environmental research, health : ERH","volume":"1 2","pages":"025003-25003"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9559325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Environmental research, health : ERH
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1