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The use of 3D-printed surgical guides and models for sinus lift surgery planning and education 使用3d打印手术指南和模型进行鼻窦提升手术计划和教育
Journal of 3D printing in medicine
Pub Date : 2019-08-01 DOI: 10.2217/3DP-2019-0014
Robert-Angelo Tuce, S. Arjoca, M. Neagu, A. Neagu
Aim: To develop 3D printing and dentistry methods for building physical models that enable one to simulate a sinus lift surgery. Materials & methods: The Blue Sky Plan software was used to create a digital model from the cone beam computed tomography scan of the subject’s maxilla and to design a surgical guide for sinus augmentation and implant placement. The anatomical model and surgical guide were 3D printed from dental resin. Results: Sinus augmentation and dental implant insertion were carried out on the model as examples of practical skills training for residents in maxillofacial surgery. Conclusion: The 3D-printed models and surgical guides are useful training materials. They could be helpful also in a dental practice for surgical planning and for illustrating the procedure to the patient.
目的:开发3D打印和牙科方法来建立物理模型，使人们能够模拟鼻窦提升手术。材料与方法:使用Blue Sky Plan软件从受试者的上颌骨锥束计算机断层扫描中创建数字模型，并设计鼻窦增强和种植体放置的手术指南。解剖模型和手术指南是用牙科树脂3D打印的。结果:以该模型为例，进行了颌面外科住院医师的鼻窦隆高术和种植牙植入术的实践技能培训。结论:3d打印模型和手术指南是有用的培训材料。在牙科实践中，他们也可以帮助制定手术计划，并向患者说明手术过程。
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引用次数: 2
An interview with Heon Ju Lee on ROCKIT Healthcare’s novel bioprinting treatment for dermal scarring 李宪柱就ROCKIT医疗的新型生物打印治疗皮肤疤痕接受采访
Journal of 3D printing in medicine
Pub Date : 2019-08-01 DOI: 10.2217/3DP-2019-0009
H. Lee
In this exclusive interview, Heon Ju Lee discusses ROCKIT healthcare’s novel bioprinting technique used to treat patients with dermal scarring. This interview was conducted by Mike Gregg, Commissioning Editor of the Journal of 3D Printing in Medicine. Dr Heon Ju Lee is the Chief Technology Officer and Managing Director of ROKIT. He is developing the service platform technology for artificial organ regeneration and supervises the overseas business development for the propagation of such service platforms. The focus of these platforms, bringing bio 3D print-based medical therapies into the operating room, on tissues that are relatively easy to fabricate structurally with the current technology, this includes skin, cartilage, hair, retina and heart patch regeneration. Dr Lee has a PhD from MIT in mechanical engineering and has been working as a 3D/4D printing group leader at KIST.
在这次独家采访中，Heon Ju Lee讨论了ROCKIT医疗保健公司用于治疗皮肤疤痕患者的新型生物打印技术。这次采访是由医学3D打印杂志的委托编辑Mike Gregg进行的。Heon Ju Lee博士是ROKIT的首席技术官兼董事总经理。研发人工器官再生服务平台技术，并负责该服务平台传播的海外业务拓展。这些平台的重点是将基于生物3D打印的医疗疗法引入手术室，利用现有技术在结构上相对容易制造的组织，包括皮肤、软骨、头发、视网膜和心脏贴片再生。李博士拥有麻省理工学院机械工程博士学位，并一直在KIST担任3D/4D打印小组负责人。
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引用次数: 0
 3D-printed pediatric temporal bone models for surgical training: a patient-specific and low-cost alternative 用于外科训练的3d打印儿科颞骨模型:一种针对患者的低成本替代方案
Journal of 3D printing in medicine
Pub Date : 2019-08-01 DOI: 10.2217/3DP-2019-0011
J. Ospina, A. Fandiño, S. Hernández, L. Uriza, Diego Aragonéz, I. Mondragón, D. Durán, J. Magness
Aim: To determine the usefulness of low-cost 3D-printed pediatric temporal bone models and to define if they could be used as a tool for large-scale surgical training based on their affordability. Materials & methods: Prototypes of a pediatric temporal bone were printed using fused deposition modeling 3D printing technique. The prototypes were drilled. The surgical simulation experience was registered by means of a Likert scale questionnaire. Results: The prototypes adequately simulated a cadaveric temporal bone. The costs associated with production were low compared with other commercial models making it a cost-effective alternative for a temporal bone laboratory. Conclusion: Printed temporal bones created by means of fused deposition modeling are useful for surgical simulation and training in otolaryngology, and it is possible to achieve detailed low-cost models.
目的:确定低成本3d打印儿童颞骨模型的实用性，并根据其可负担性来确定它们是否可以用作大规模手术培训的工具。材料和方法:使用熔融沉积建模3D打印技术打印儿童颞骨原型。原型机被钻了出来。通过李克特量表问卷记录手术模拟经验。结果:该模型充分模拟了尸体颞骨。与其他商业模型相比，与生产相关的成本较低，使其成为颞骨实验室具有成本效益的替代方案。结论:采用熔融沉积模型制作的打印颞骨可用于耳鼻喉外科手术模拟和训练，并且可以实现详细的低成本模型。
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引用次数: 2
3D bioprinting for oncology applications. 肿瘤学应用的3D生物打印。
Journal of 3D printing in medicine
Pub Date : 2019-06-01 Epub Date: 2019-05-30 DOI: 10.2217/3dp-2019-0004
Tingting Liu, Clement Delavaux, Yu Shrike Zhang
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引用次数: 0
3D printing in drug delivery systems. 三维打印给药系统。
Journal of 3D printing in medicine
Pub Date : 2019-06-01 Epub Date: 2019-05-31 DOI: 10.2217/3dp-2019-0005
Jaidev L Chakka, Aliasger K Salem
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引用次数: 0
Antibiotics in 3D-printed implants, instruments and materials: benefits, challenges and future directions. 3d打印植入物、器械和材料中的抗生素:益处、挑战和未来方向。
Journal of 3D printing in medicine
Pub Date : 2019-06-01 Epub Date: 2019-05-31 DOI: 10.2217/3dp-2019-0007
David H Ballard, Karthik Tappa, Christen J Boyer, Udayabhanu Jammalamadaka, Kavya Hemmanur, Jeffery A Weisman, Jonathan S Alexander, David K Mills, Pamela K Woodard

3D printing is an additive manufacturing technology, which permits innovative approaches for incorporating antibiotics into 3D printed constructs. Antibiotic-incorporating applications in medicine have included medical implants, prostheses, along with procedural and surgical instruments. 3D-printed antibiotic-impregnated devices offer the advantages of increased surface area for drug distribution, sequential layers of antibiotics produced through layer-by-layer fabrication, and the ability to rapidly fabricate constructs based on patient-specific anatomies. To date, fused deposition modeling has been the main 3D printing method used to incorporate antibiotics, although inkjet and stereolithography techniques have also been described. This review offers a state-of-the-art summary of studies that incorporate antibiotics into 3D-printed constructs and summarizes the rationale, challenges, and future directions for the potential use of this technology in patient care.

3D打印是一种增材制造技术，它允许将抗生素纳入3D打印结构的创新方法。抗生素在医学上的应用包括医疗植入物、假肢以及手术和手术器械。3d打印的抗生素浸渍设备具有以下优点:增加了药物分布的表面积，通过逐层制造生产的连续抗生素层，以及基于患者特定解剖结构快速制造结构的能力。迄今为止，尽管喷墨和立体光刻技术也被描述，但熔融沉积建模一直是用于结合抗生素的主要3D打印方法。本综述提供了将抗生素纳入3d打印结构的最新研究总结，并总结了该技术在患者护理中的潜在应用的基本原理、挑战和未来方向。
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引用次数: 18
The optimization of a 3D scanning technique applied for 3D printing of bespoke medical devices 应用于定制医疗设备3D打印的3D扫描技术的优化
Journal of 3D printing in medicine
Pub Date : 2019-05-31 DOI: 10.2217/3dp-2018-0026
A. Geierlehner, S. Malferrari, D. Kalaskar
Aim: The aim of this study is to optimize the 3D scanning process using a laser-free structured light surface scanner (Artec EVA). Methods: The hand was chosen to optimize scanning protocols and generate reliable high-quality surface scan models. Scanning comfort, ease of scanning and maximum scanning error were assessed in each hand position. Results & conclusion: Such an optimized scanning method shows the potential to obtain high-quality 3D hand scans quickly and reliably so that they can further be used for the development of bespoke 3D-printed medical devices for patients.
目的:本研究的目的是利用无激光结构光表面扫描仪(Artec EVA)优化三维扫描过程。方法:选择手为扫描对象，优化扫描方案，生成可靠、高质量的表面扫描模型。对各手位的扫描舒适度、扫描易用性和最大扫描误差进行了评估。结果与结论:这种优化的扫描方法显示了快速可靠地获得高质量3D手部扫描的潜力，从而可以进一步用于为患者开发定制的3D打印医疗设备。
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引用次数: 3
Novel technique produces micropores, allowing diffusion of nutrients in biofabricated tissues 新技术产生微孔，允许营养物质在生物组织中扩散
Journal of 3D printing in medicine
Pub Date : 2019-05-01 DOI: 10.2217/3DP-2019-0002
Yang Wu
Dr Yang Wu is a postdoctoral fellow and lab manager at the 3D Bioprinting Lab at Penn State. His research interests involve 3D bioprinting and regenerative medicine, such as development of tissue strands as bioink for osteochondral tissue bioprinting, skin bioprinting and pancreatic organ printing in the field of diabetes research. As a postdoctoral scholar at Penn State, he has been leading several fundamental studies. Prior to this, he was a postdoctoral fellow in the department of mechanical engineering, National University of Singapore, where he also completed his PhD in the field of 3D bioprinting. He received his BEng in Zhejiang University, Hangzhou, China.
杨武博士是宾夕法尼亚州立大学3D生物打印实验室的博士后研究员和实验室经理。他的研究兴趣涉及生物3D打印和再生医学，如开发组织链作为骨软骨组织生物打印的生物链接，皮肤生物打印和糖尿病研究领域的胰腺器官打印。作为宾夕法尼亚州立大学的博士后学者，他领导了几项基础研究。在此之前，他是新加坡国立大学机械工程系的博士后，在那里他还完成了3D生物打印领域的博士学位。他在中国杭州的浙江大学获得学士学位。
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引用次数: 0
The future of biomimetic 3D printing 仿生3D打印的未来
Journal of 3D printing in medicine
Pub Date : 2019-05-01 DOI: 10.2217/3DP-2019-0006
Jacob Koffler
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引用次数: 1
Three-dimensional printing for drug delivery devices: a state-of-the-art survey 药物输送装置的三维打印:一项最新的调查
Journal of 3D printing in medicine
Pub Date : 2019-05-01 DOI: 10.2217/3DP-2018-0023
A. Uziel, Tal Shpigel, Nir Goldin, D. Lewitus
Over the last several decades, 3D printing technology, which encompasses many different fabrication techniques, had emerged as a promising tool in many fields of production, including the pharmaceutical industry. Specifically, 3D printing may be advantageous for drug delivery systems, systems aiming to improve the pharmacokinetics of drugs. These advantages include the ease of designing complex shapes, printing of drugs on demand, tailoring dosage to the specific needs of the patient and enhancing the bioavailability of drugs. This paper reviews the most recent advancements in this field, presenting both the abilities and limitations of several promising 3D printing methods.
在过去的几十年里，3D打印技术包含了许多不同的制造技术，已经成为包括制药行业在内的许多生产领域的一种有前途的工具。具体来说，3D打印可能有利于药物输送系统，旨在改善药物的药代动力学的系统。这些优点包括易于设计复杂形状、按需打印药物、根据患者的具体需要定制剂量以及提高药物的生物利用度。本文回顾了该领域的最新进展，介绍了几种有前途的3D打印方法的能力和局限性。
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引用次数: 4
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