Pub Date : 2020-02-13DOI: 10.11648/J.IJIDT.20200501.11
M. Koné, H. Awobode
Background: Toxoplasma gondii infections cause serious complications in HIV-infected pregnant women, leading to miscarriages, stillbirths, birth defects such as mental retardation, blindness, epilepsy, and could favour or enhance the mother-to-child transmission of HIV. Worldwide, 30% of the population have antibodies to the intracellular protozoan parasite Toxoplasma gondii and about 36.7 million people are infected with HIV, however little is known about the prevalence of co-infection of Toxoplasma gondii and HIV in pregnancy. We report co-infection of Toxoplasma gondii and HIV in pregnant women in Mali. Methods: Toxoplasma gondii anti- IgG, IgM and HIV Combi PT serology were performed in sera from pregnant women using the Elecsys system. The HIV genotyping was performed using the Tri-DOT technique. Results: One pregnant woman out of 247 screened was anti-Toxoplasma IgM positive and HIV type I positive. An anti-Toxoplasma gondii IgM positive reading is an indication of an acute/current infection. Conclusion: This suggests there is active toxoplasmosis transmission and therefore a possible risk for congenital infections in Bamako. HIV infection being endemic in Mali may accentuate toxoplasmosis pathology in this region. Toxoplasmosis surveillance and awareness are therefore necessary in Bamako to stem the scourge of this neglected infection.
{"title":"Co-infection of Toxoplasma gondii and HIV Infections in Pregnancy in Bamako - A Case Report","authors":"M. Koné, H. Awobode","doi":"10.11648/J.IJIDT.20200501.11","DOIUrl":"https://doi.org/10.11648/J.IJIDT.20200501.11","url":null,"abstract":"Background: Toxoplasma gondii infections cause serious complications in HIV-infected pregnant women, leading to miscarriages, stillbirths, birth defects such as mental retardation, blindness, epilepsy, and could favour or enhance the mother-to-child transmission of HIV. Worldwide, 30% of the population have antibodies to the intracellular protozoan parasite Toxoplasma gondii and about 36.7 million people are infected with HIV, however little is known about the prevalence of co-infection of Toxoplasma gondii and HIV in pregnancy. We report co-infection of Toxoplasma gondii and HIV in pregnant women in Mali. Methods: Toxoplasma gondii anti- IgG, IgM and HIV Combi PT serology were performed in sera from pregnant women using the Elecsys system. The HIV genotyping was performed using the Tri-DOT technique. Results: One pregnant woman out of 247 screened was anti-Toxoplasma IgM positive and HIV type I positive. An anti-Toxoplasma gondii IgM positive reading is an indication of an acute/current infection. Conclusion: This suggests there is active toxoplasmosis transmission and therefore a possible risk for congenital infections in Bamako. HIV infection being endemic in Mali may accentuate toxoplasmosis pathology in this region. Toxoplasmosis surveillance and awareness are therefore necessary in Bamako to stem the scourge of this neglected infection.","PeriodicalId":73792,"journal":{"name":"Journal of infectious disease and therapy","volume":"5 1","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2020-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41761006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-07-19DOI: 10.11648/J.IJIDT.20190402.12
Walelign Azene Demelash, D. Birri
Leishmaniasis is a disease caused by protozoan parasites of the genus Leishmania. Visceral leishmaniasis (VL) affects many people in some parts of Ethiopia, with occasional outbreaks. Community participation and disease trends are of paramount importance in the control of infectious diseases, including VL. The aim of this study was to assess the knowledge, attitude and practice related to VL in four endemic kebeles (sub-districts) of Libo Kemkem wereda (district), Northwest Ethiopia, and to determine the trend of VL in the same district in the last fourteen years (April 2005- December 2018). In order to assess the knowledge, attitude and practice (KAP) related to VL, a community-based cross-sectional study was conducted in four endemic kebeles of Libo Kemkem woreda, Northwest Ethiopia. Three hundred ninety-eight (398) study participants (200 males and 198 females) were selected by systematic random sampling and questionnaires were used to collect data. A retrospective study was done to determine the trend of VL in Libo Kemkem woreda in the past fourteen years (April 2005-December 2018) using data collected from patients’ registration book at the Addis zemen hospital and local health centers. The results from the questionnaire survey revealed that 97.7% of the respondents heard about VL before, but only 12.8% and 5.3% knew the etiologic agent and the vector of the disease, respectively. Nearly all respondents (97.2%) believed that health education is necessary to minimize the challenges of the disease. Close to half (44.5%) of the respondents believed that a complete cure of the disease is possible. Approximately 88% of the respondents did not practice anything to protect themselves from the Sand fly bite. The occurrence of VL in Libo Kemkem wereda decreased from 2005 to 2008 and then gradually increased in the next five years (2008 to 2013) and slightly decreased over the last five years (2013-2018). The disease spread to 27 kebeles (subdistricts) in recent years. The overall study revealed that the local societies have a low level of knowledge, attitude, and practice related to VL. VL showed a little decreasing trend over the recent consecutive years. Hence, educating the local community about VL and mobilizing them to take preventive measures is crucial in effective control of VL in the study area.
{"title":"Knowledge, Attitude and Practices Related to Visceral Leishmaniasis and Its Trend in Libo Kem Kem Wereda, Northwest Ethiopia: A Cross-Sectional and Retrospective Study","authors":"Walelign Azene Demelash, D. Birri","doi":"10.11648/J.IJIDT.20190402.12","DOIUrl":"https://doi.org/10.11648/J.IJIDT.20190402.12","url":null,"abstract":"Leishmaniasis is a disease caused by protozoan parasites of the genus Leishmania. Visceral leishmaniasis (VL) affects many people in some parts of Ethiopia, with occasional outbreaks. Community participation and disease trends are of paramount importance in the control of infectious diseases, including VL. The aim of this study was to assess the knowledge, attitude and practice related to VL in four endemic kebeles (sub-districts) of Libo Kemkem wereda (district), Northwest Ethiopia, and to determine the trend of VL in the same district in the last fourteen years (April 2005- December 2018). In order to assess the knowledge, attitude and practice (KAP) related to VL, a community-based cross-sectional study was conducted in four endemic kebeles of Libo Kemkem woreda, Northwest Ethiopia. Three hundred ninety-eight (398) study participants (200 males and 198 females) were selected by systematic random sampling and questionnaires were used to collect data. A retrospective study was done to determine the trend of VL in Libo Kemkem woreda in the past fourteen years (April 2005-December 2018) using data collected from patients’ registration book at the Addis zemen hospital and local health centers. The results from the questionnaire survey revealed that 97.7% of the respondents heard about VL before, but only 12.8% and 5.3% knew the etiologic agent and the vector of the disease, respectively. Nearly all respondents (97.2%) believed that health education is necessary to minimize the challenges of the disease. Close to half (44.5%) of the respondents believed that a complete cure of the disease is possible. Approximately 88% of the respondents did not practice anything to protect themselves from the Sand fly bite. The occurrence of VL in Libo Kemkem wereda decreased from 2005 to 2008 and then gradually increased in the next five years (2008 to 2013) and slightly decreased over the last five years (2013-2018). The disease spread to 27 kebeles (subdistricts) in recent years. The overall study revealed that the local societies have a low level of knowledge, attitude, and practice related to VL. VL showed a little decreasing trend over the recent consecutive years. Hence, educating the local community about VL and mobilizing them to take preventive measures is crucial in effective control of VL in the study area.","PeriodicalId":73792,"journal":{"name":"Journal of infectious disease and therapy","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64794677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-02-11DOI: 10.4172/2332-0877-C4-048
pPrasanth Venelap
{"title":"Measurement of compliance to hand hygiene by healthcare workers in tertiary care hospitals of South India: An observational cross sectional study","authors":"pPrasanth Venelap","doi":"10.4172/2332-0877-C4-048","DOIUrl":"https://doi.org/10.4172/2332-0877-C4-048","url":null,"abstract":"","PeriodicalId":73792,"journal":{"name":"Journal of infectious disease and therapy","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70297226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-02-11DOI: 10.4172/2332-0877-C4-047
pPaul J Caesarp
{"title":"Infection Control: Through the barricades?!","authors":"pPaul J Caesarp","doi":"10.4172/2332-0877-C4-047","DOIUrl":"https://doi.org/10.4172/2332-0877-C4-047","url":null,"abstract":"","PeriodicalId":73792,"journal":{"name":"Journal of infectious disease and therapy","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70297216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-02-11DOI: 10.4172/2332-0877-C4-046
pMelissa Stefkop
{"title":"Prevention of contamination in pharmaceutical industry","authors":"pMelissa Stefkop","doi":"10.4172/2332-0877-C4-046","DOIUrl":"https://doi.org/10.4172/2332-0877-C4-046","url":null,"abstract":"","PeriodicalId":73792,"journal":{"name":"Journal of infectious disease and therapy","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70297173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-02-04DOI: 10.4172/2332-0877-C7-056
pKavita Diddip
{"title":"Dengue epidemiology and vaccine: Current status","authors":"pKavita Diddip","doi":"10.4172/2332-0877-C7-056","DOIUrl":"https://doi.org/10.4172/2332-0877-C7-056","url":null,"abstract":"","PeriodicalId":73792,"journal":{"name":"Journal of infectious disease and therapy","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70297371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-02-04DOI: 10.4172/2332-0877-C7-055
pCrystal M Jamesp
{"title":"Defining health security: Neglected diseases in rural Alabama","authors":"pCrystal M Jamesp","doi":"10.4172/2332-0877-C7-055","DOIUrl":"https://doi.org/10.4172/2332-0877-C7-055","url":null,"abstract":"","PeriodicalId":73792,"journal":{"name":"Journal of infectious disease and therapy","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70297355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-02-04DOI: 10.4172/2332-0877-C7-057
pSachin Damkep
{"title":"Correlation of dengue serology with disease severity","authors":"pSachin Damkep","doi":"10.4172/2332-0877-C7-057","DOIUrl":"https://doi.org/10.4172/2332-0877-C7-057","url":null,"abstract":"","PeriodicalId":73792,"journal":{"name":"Journal of infectious disease and therapy","volume":"06 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70297427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-28DOI: 10.4172/2332-0877-C5-050
Gehan Salah Sadekp
Fatma Hamed Shalan1, Ayman Abd El-Moenem Elbadry2, Amera Fathy Afifi1, Engy Victor Nassief Beshay1, Samar Ahmed El-Refai1, Hala Gabr Metwaly3, Eman Ahmedy4, Eman Abd El-Fattah Badr5, Dalia Refaat Al-Sharaky6 and Gehan Salah Sadek1 1Parasitology Department, Faculty of Medicine, Menoufia University, Egypt 2Parasitology Department, Faculty of Medicine, Cairo University, Egypt 3Clinical Pathology Department, Faculty of Medicine, Cairo University, Egypt 4Clinical Pathology Department, Faculty of Medicine, Menoufia University, Egypt 5Biochemistry Department, Faculty of Medicine, Menoufia University, Egypt 6Pathology Department, Faculty of Medicine, Menoufia University, Egypt
Fatma Hamed Shalan1, Ayman Abd El-Moenem Elbadry2, Amera Fathy Afifi1, Engy Victor Nassief Beshay1, Samar Ahmed El-Refai1, Hala Gabr Metwaly3, Eman Ahmedy4, Eman Abd El-Fattah Badr5, Dalia Refaat Al-Sharaky6和Gehan Salah sade1 1埃及Menoufia大学医学院寄生虫学系2埃及开罗大学医学院寄生虫学系3埃及开罗大学医学院临床病理学系4临床病理学系埃及Menoufia大学医学院5埃及Menoufia大学医学院生物化学系6埃及Menoufia大学医学院病理学系
{"title":"Mesenchymal stem cell as a cure for brain damage induced by chronic Toxocara canis infection in an experimental mouse model","authors":"Gehan Salah Sadekp","doi":"10.4172/2332-0877-C5-050","DOIUrl":"https://doi.org/10.4172/2332-0877-C5-050","url":null,"abstract":"Fatma Hamed Shalan1, Ayman Abd El-Moenem Elbadry2, Amera Fathy Afifi1, Engy Victor Nassief Beshay1, Samar Ahmed El-Refai1, Hala Gabr Metwaly3, Eman Ahmedy4, Eman Abd El-Fattah Badr5, Dalia Refaat Al-Sharaky6 and Gehan Salah Sadek1 1Parasitology Department, Faculty of Medicine, Menoufia University, Egypt 2Parasitology Department, Faculty of Medicine, Cairo University, Egypt 3Clinical Pathology Department, Faculty of Medicine, Cairo University, Egypt 4Clinical Pathology Department, Faculty of Medicine, Menoufia University, Egypt 5Biochemistry Department, Faculty of Medicine, Menoufia University, Egypt 6Pathology Department, Faculty of Medicine, Menoufia University, Egypt","PeriodicalId":73792,"journal":{"name":"Journal of infectious disease and therapy","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70297279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-28DOI: 10.4172/2332-0877-C5-051
pMohammed Hussein Eltoum Salihp
{"title":"Impact of mass treatment and health education on the prevalence of Schistosomia haematobium among school children in four villages, White Nile State, Sudan (2013- 2015)","authors":"pMohammed Hussein Eltoum Salihp","doi":"10.4172/2332-0877-C5-051","DOIUrl":"https://doi.org/10.4172/2332-0877-C5-051","url":null,"abstract":"","PeriodicalId":73792,"journal":{"name":"Journal of infectious disease and therapy","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70297288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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