Bacteria, influenza, parasites and fungi are pathogenic microorganisms that cause infectious diseases. Diseases can spread from one individual to another, either directly or indirectly. Infectious diseases are world’s second most common cause of death. Rainforest plants provide about quarter of drugs we need. Scientific research has been carried out on few medicinal plants, but only to small degree. Bacterial susceptibility to currently active antibiotics has necessitated discovery of new antibacterial agents. Several plants are widely used as herbal medicine for treatment of infectious diseases in rural and backward areas of India. This chapter looks over the publications on medicinal plants that are used to cure diseases like malaria, pneumonia. Traditional medicine is preferred primary health care system in many rural areas for variety of reasons, including its affordability and efficacy. The current study focused on existing medicinal plant literature, with ethnobotany, phytochemistry and pharmacology details being highlighted. All of examined plants showed potent action, supporting their conventional uses as well as their ability to cure common diseases. Curcuma longa L., Punica granatum L. and Justicia adhatoda L. were most widely used plant families for pneumonia therapy in research area (each with seven plants); of these, Curcuma longa L., Punica granatum L. and Justicia adhatoda L. had most inhibiting ability against Staphylococcus aureus and Streptococcus pneumoniae. Ascorbic acid, curcumin, vasicine, piperine, quercetin, myricetin and gallic acid have all been derived from these plants and are said to have antibacterial properties. Although Himalayan region has wide range of ethnomedicinal plants used to treat pneumonia, research on in-vivo activity, toxicology, and mechanism of action is minimal. As result, in order to produce novel antibacterial drugs from studied plant species, thorough study of these aspects is needed.
细菌、流感、寄生虫和真菌是引起传染病的病原微生物。疾病可以直接或间接地从一个人传染给另一个人。传染病是世界上第二大常见死因。雨林植物提供了我们所需药物的四分之一。对一些药用植物进行了科学研究，但研究程度很低。细菌对目前有效的抗生素的敏感性使得发现新的抗菌剂成为必要。在印度的农村和落后地区，有几种植物被广泛用作治疗传染病的草药。这一章回顾了用于治疗疟疾、肺炎等疾病的药用植物的出版物。由于各种原因，包括其可负担性和有效性，传统医学在许多农村地区是首选的初级卫生保健系统。目前的研究主要集中在现有的药用植物文献上，突出了民族植物学、植物化学和药理学的细节。所有被检测的植物都显示出有效的作用，支持它们的传统用途以及治疗常见疾病的能力。姜黄(Curcuma longa L.)、石榴树(Punica granatum L.)和苦参(Justicia adhatoda L.)是研究区应用最广泛的治疗肺炎植物科(各7株);其中对金黄色葡萄球菌和肺炎链球菌的抑制能力最强的是姜黄、石榴和白芷。抗坏血酸、姜黄素、缬草碱、胡椒碱、槲皮素、杨梅素和没食子酸都是从这些植物中提取的，据说它们具有抗菌特性。虽然喜马拉雅地区有广泛的民族药用植物用于治疗肺炎，但对其体内活性、毒理学和作用机制的研究很少。因此，为了从已研究的植物物种中生产出新的抗菌药物，需要对这些方面进行深入的研究。
{"title":"Recent Advances of the Medicinal Plant Compound for Combating Pneumonia Disease: A Review","authors":"Megha Patel, Bhavesh Sharma","doi":"10.52916/jmrs214063","DOIUrl":"https://doi.org/10.52916/jmrs214063","url":null,"abstract":"Bacteria, influenza, parasites and fungi are pathogenic microorganisms that cause infectious diseases. Diseases can spread from one individual to another, either directly or indirectly. Infectious diseases are world’s second most common cause of death. Rainforest plants provide about quarter of drugs we need. Scientific research has been carried out on few medicinal plants, but only to small degree. Bacterial susceptibility to currently active antibiotics has necessitated discovery of new antibacterial agents. Several plants are widely used as herbal medicine for treatment of infectious diseases in rural and backward areas of India. This chapter looks over the publications on medicinal plants that are used to cure diseases like malaria, pneumonia. Traditional medicine is preferred primary health care system in many rural areas for variety of reasons, including its affordability and efficacy. The current study focused on existing medicinal plant literature, with ethnobotany, phytochemistry and pharmacology details being highlighted. All of examined plants showed potent action, supporting their conventional uses as well as their ability to cure common diseases. Curcuma longa L., Punica granatum L. and Justicia adhatoda L. were most widely used plant families for pneumonia therapy in research area (each with seven plants); of these, Curcuma longa L., Punica granatum L. and Justicia adhatoda L. had most inhibiting ability against Staphylococcus aureus and Streptococcus pneumoniae. Ascorbic acid, curcumin, vasicine, piperine, quercetin, myricetin and gallic acid have all been derived from these plants and are said to have antibacterial properties. Although Himalayan region has wide range of ethnomedicinal plants used to treat pneumonia, research on in-vivo activity, toxicology, and mechanism of action is minimal. As result, in order to produce novel antibacterial drugs from studied plant species, thorough study of these aspects is needed.","PeriodicalId":73820,"journal":{"name":"Journal of medical research and surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42636360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Our research reveals that non-toxic creatine derivatives, especially N-acetyl-creatine ethyl ester, to be therapeutically effective on topical application or by superficial subcutaneous injection over sites of pain to rapidly alleviate or eliminate pain associated with various inflammatory conditions including arthritis, acute common headache, osteoarthritis, psoriatic arthritis, rheumatoid arthritis and various other pains associated with inflammation.
{"title":"Creatine Derivatives: Rapid Complete Relief of Pain by Topical or Transcutaneous Administration","authors":"Ruey J. Yu","doi":"10.52916/jmrs214064","DOIUrl":"https://doi.org/10.52916/jmrs214064","url":null,"abstract":"Our research reveals that non-toxic creatine derivatives, especially N-acetyl-creatine ethyl ester, to be therapeutically effective on topical application or by superficial subcutaneous injection over sites of pain to rapidly alleviate or eliminate pain associated with various inflammatory conditions including arthritis, acute common headache, osteoarthritis, psoriatic arthritis, rheumatoid arthritis and various other pains associated with inflammation.","PeriodicalId":73820,"journal":{"name":"Journal of medical research and surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48402881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Iffat Ara Begum, Zannatul Raiyana, Md. Abdul Mazid Azad, M. S. Huda, A. Anwar, Md Ebrahim Khalil, Abu Ansar Md. Rizwan
Introduction: Diseases of elder people are a global problem. The prevalence of disease in elderly people is increasing day by day as old people often have limited regenerative abilities and are more susceptible to disease, syndromes, injuries, and sickness than younger adults. Objective: This study was conducted to identify the disease pattern of geriatric people of the host community in Cox's Bazar, Bangladesh. Method: A descriptive type of cross-sectional study was conducted among 381 geriatric persons in 5 selected hospitals of Cox's Bazar. The sample size was calculated in a 95% confidence interval and with a 5% level of significance. Data collection was done by using a semi-structured pre-tested questionnaire. Data quality was ensured through multiple procedures of review and cross-checking. Results: The findings revealed that a total of 32.0% had heart disease and 31% had arthritis. More than one-fifth (22.0%) of the respondents had diabetes and 18% of the total respondents had different types of communicable diseases. The occurrence of non-communicable diseases in geriatric people is significantly associated with their age and sex. Conclusion: The findings from this study illustrate that non-communicable disease is very much prevalent among the geriatric population as well as a threat to public health. The hospitals and health service providers should emphasize the management and prevention of these diseases. Also, lifestyle modification can play a vital role in preventing non-communicable diseases.
{"title":"Disease Pattern of Geriatric People of the Host Community in Cox's Bazar, Bangladesh","authors":"Iffat Ara Begum, Zannatul Raiyana, Md. Abdul Mazid Azad, M. S. Huda, A. Anwar, Md Ebrahim Khalil, Abu Ansar Md. Rizwan","doi":"10.52916/jmrs214062","DOIUrl":"https://doi.org/10.52916/jmrs214062","url":null,"abstract":"Introduction: Diseases of elder people are a global problem. The prevalence of disease in elderly people is increasing day by day as old people often have limited regenerative abilities and are more susceptible to disease, syndromes, injuries, and sickness than younger adults. Objective: This study was conducted to identify the disease pattern of geriatric people of the host community in Cox's Bazar, Bangladesh. Method: A descriptive type of cross-sectional study was conducted among 381 geriatric persons in 5 selected hospitals of Cox's Bazar. The sample size was calculated in a 95% confidence interval and with a 5% level of significance. Data collection was done by using a semi-structured pre-tested questionnaire. Data quality was ensured through multiple procedures of review and cross-checking. Results: The findings revealed that a total of 32.0% had heart disease and 31% had arthritis. More than one-fifth (22.0%) of the respondents had diabetes and 18% of the total respondents had different types of communicable diseases. The occurrence of non-communicable diseases in geriatric people is significantly associated with their age and sex. Conclusion: The findings from this study illustrate that non-communicable disease is very much prevalent among the geriatric population as well as a threat to public health. The hospitals and health service providers should emphasize the management and prevention of these diseases. Also, lifestyle modification can play a vital role in preventing non-communicable diseases.","PeriodicalId":73820,"journal":{"name":"Journal of medical research and surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44095506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Schwannoma of the glans is a rare clinical entity. The diagnosis is histological. Treatment is surgical, with complete excision. The authors report this rare case encountered at the University Hospital of Libreville in order to identify its clinical and therapeutic characteristics. Observation: Mr. I.B, 50 years old, with no medical-surgical history, consulted for swelling of the glans evolving for 06 years, preventing coitus. He reported a notion of poor healing from an acorn sore after the trouser fly was closed. The diagnostic suspicion was a glans keloid. A complete resection was performed. Histologic examination favored a glans schwannoma. Healing was effective on D7 postoperatively. Erectile functions have been preserved. Conclusion: The glans schwannoma is rare. Surgical treatment gives good results.
{"title":"The Glans Schwannoma: A Rare Clinical Entity","authors":"Diallo Kadidiatou Folly, Dyatta Mayombo Kévin, A. Gabrielle, Ipouka Doussiemou Sergina, Nguele Ndjota, Afoughe Mayombo Ornela Priscilia, Mpira Yves Marien","doi":"10.52916/jmrs21s105","DOIUrl":"https://doi.org/10.52916/jmrs21s105","url":null,"abstract":"Introduction: Schwannoma of the glans is a rare clinical entity. The diagnosis is histological. Treatment is surgical, with complete excision. The authors report this rare case encountered at the University Hospital of Libreville in order to identify its clinical and therapeutic characteristics. Observation: Mr. I.B, 50 years old, with no medical-surgical history, consulted for swelling of the glans evolving for 06 years, preventing coitus. He reported a notion of poor healing from an acorn sore after the trouser fly was closed. The diagnostic suspicion was a glans keloid. A complete resection was performed. Histologic examination favored a glans schwannoma. Healing was effective on D7 postoperatively. Erectile functions have been preserved. Conclusion: The glans schwannoma is rare. Surgical treatment gives good results.","PeriodicalId":73820,"journal":{"name":"Journal of medical research and surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47639280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sebastián Rosero Cabrera, William Pinzón Gallardo, Helberth Augusto González Rico, C. Gomez, Tulio Sotomayor Medina, Andrea Carolina Wilcox Robles, Decknia Luz Vásquez Moris, Carlos José González Tejeda
The deformities of the lower limbs (genu valgus and genu varus) are alterations frequently developed properly by physiological processes which usually disappear at 2 years (genu varus) and at 7-8 years (genu valgus), being considered in adults normal a 4º-6º genu valgus, however the appearance of the latter is also related to various metabolic pathologies, tumors, traumatic sequelae, infections, skeletal dysplastic and idiopathic genu valgus. In the bibliography, there is a greater consensus on the approach to varus deformity, not so in valgus deformities, where there is no bibliography with a level of evidence that defines established protocols to treat severe valgus deformities>20, currently good treatment results have been demonstrated by means of knee arthroplasty to correct genu valgus deformities, which showed good results in the alignment of the lower extremities through the balance of ligaments in patients with severe genu valgus with pain reduction. , improvements in knee function and with a low rate of complications, the use of these alternatives such as the external approach in total knee replacement in patients with severe genu valgus and medial collateral ligament insufficiency allows correcting large deformities using a technique simple and in most cases without the use of a prosthesis that generates a degree of constraint, progressively improving their living conditions.
{"title":"Use of External Approach for Severe Genu Valgo Knee Arthroplasty","authors":"Sebastián Rosero Cabrera, William Pinzón Gallardo, Helberth Augusto González Rico, C. Gomez, Tulio Sotomayor Medina, Andrea Carolina Wilcox Robles, Decknia Luz Vásquez Moris, Carlos José González Tejeda","doi":"10.52916/jmrs214061","DOIUrl":"https://doi.org/10.52916/jmrs214061","url":null,"abstract":"The deformities of the lower limbs (genu valgus and genu varus) are alterations frequently developed properly by physiological processes which usually disappear at 2 years (genu varus) and at 7-8 years (genu valgus), being considered in adults normal a 4º-6º genu valgus, however the appearance of the latter is also related to various metabolic pathologies, tumors, traumatic sequelae, infections, skeletal dysplastic and idiopathic genu valgus. In the bibliography, there is a greater consensus on the approach to varus deformity, not so in valgus deformities, where there is no bibliography with a level of evidence that defines established protocols to treat severe valgus deformities>20, currently good treatment results have been demonstrated by means of knee arthroplasty to correct genu valgus deformities, which showed good results in the alignment of the lower extremities through the balance of ligaments in patients with severe genu valgus with pain reduction. , improvements in knee function and with a low rate of complications, the use of these alternatives such as the external approach in total knee replacement in patients with severe genu valgus and medial collateral ligament insufficiency allows correcting large deformities using a technique simple and in most cases without the use of a prosthesis that generates a degree of constraint, progressively improving their living conditions.","PeriodicalId":73820,"journal":{"name":"Journal of medical research and surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45844475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Faruk Hernández Sampayo, Gabriela Carvajales Lozano, María Yuliana Amell Wilches
Introduction: Hernias are abnormal protrusions of any abdominal-pelvic or fat organ, which are produced by a defect in the abdominal wall, the most frequent are inguinal hernias and their content is generally of the omentum or intestinal loops, the presence of pelvic organs is very infrequent and the majority of cases described are in children under five years of age. Objective: To analyze the entity in connection with a case of a patient with a tubo-ovarian inguinal hernia. Clinical case: The case of a 34-year-old female patient is presented, who was under follow-up by the gynecology service due to the presence of a left ovarian cyst, with symptoms of pain in the left iliac fossa for more than 6 months of evolution. which is performed an ultrasound, which reports left inguinal hernia for what is electively scheduled by the general surgery service, when performing the herniorrhaphy incarcerated hernia with left ovary with bleeding follicle and fallopian tube is evidenced. Conclusions: These types of findings are infrequent, documented in the literature with a global incidence of Tubo-ovarian inguinal hernias ranging from 0-8-4.4%, however it is worth clarifying that these studies are in infant patients, so its presentation in adults associated with a hemorrhagic follicle is anecdotal as in this case.
{"title":"Tubo-Ovarian Inguinal Hernia with Ruptured Bleeding Follicle: A Case Report","authors":"Faruk Hernández Sampayo, Gabriela Carvajales Lozano, María Yuliana Amell Wilches","doi":"10.52916/jmrs214060","DOIUrl":"https://doi.org/10.52916/jmrs214060","url":null,"abstract":"Introduction: Hernias are abnormal protrusions of any abdominal-pelvic or fat organ, which are produced by a defect in the abdominal wall, the most frequent are inguinal hernias and their content is generally of the omentum or intestinal loops, the presence of pelvic organs is very infrequent and the majority of cases described are in children under five years of age. Objective: To analyze the entity in connection with a case of a patient with a tubo-ovarian inguinal hernia. Clinical case: The case of a 34-year-old female patient is presented, who was under follow-up by the gynecology service due to the presence of a left ovarian cyst, with symptoms of pain in the left iliac fossa for more than 6 months of evolution. which is performed an ultrasound, which reports left inguinal hernia for what is electively scheduled by the general surgery service, when performing the herniorrhaphy incarcerated hernia with left ovary with bleeding follicle and fallopian tube is evidenced. Conclusions: These types of findings are infrequent, documented in the literature with a global incidence of Tubo-ovarian inguinal hernias ranging from 0-8-4.4%, however it is worth clarifying that these studies are in infant patients, so its presentation in adults associated with a hemorrhagic follicle is anecdotal as in this case.","PeriodicalId":73820,"journal":{"name":"Journal of medical research and surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41730533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jackline V. Mbishi, S. Kamazima, H. Saronga, Saidah M. Bakari
Background: Homosexual identification among women as lesbian, bisexual or transgender does not encompass the whole pool of women who practice same-sex behavior. Straight women especially youths are more increasingly willing to have sex with fellow women. This article establishes the reasons that influence same-sex orientation and behaviors among women in Tanzania. It explores the self-reported push/pull reasons that ultimately leads women to same-sex behavior among sampled through individuals. Method: This is a cross-sectional descriptive and retrospective study which was conducted in Dar es Salaam between January and February, 2021. The participants of the study were WSW, proxy WSW, and women who at one time had female same-sex relationships. The study also used community members aged 18 years and above but only those who met the inclusion criteria. Data were collected through qualitative in-depth interviews, focus group discussions, interviews, and life stories. All the data generated through the study were analyzed thematically. Results: The findings indicate that women who practice same-sex behavior believe that their behavior occurs naturally through biological reasons. Some of them attribute earlier negative experiences with men as a trigger to opt out of heterosexual sex. Most participants also cited past unpleasant sexual experiences with men such as rape, being emotionally detached from men as factors that lead to developing desires to have sex with fellow women. Conclusion: There are biological and social-economic factors that lead women to practice same-sex behaviors. Women, who are born with male attributes become sexually unattracted to males, opt to engage in same-sex practices because of displeasure from having sex with men. Further, economic hardships in societies force women to engage in same-sex practices through peers who are financially well-off and are searching for peers to exploit sexually. Research should focus on investigating peer influence and social media’s effects on women’s decision to engage in same sex practices.
{"title":"Context Within Which Female Same-Sex Develops and Practiced in Tanzania: Qualitative Study among Women Who Have Sex with Women in Dar-es-Salaam City","authors":"Jackline V. Mbishi, S. Kamazima, H. Saronga, Saidah M. Bakari","doi":"10.52916/jmrs214059","DOIUrl":"https://doi.org/10.52916/jmrs214059","url":null,"abstract":"Background: Homosexual identification among women as lesbian, bisexual or transgender does not encompass the whole pool of women who practice same-sex behavior. Straight women especially youths are more increasingly willing to have sex with fellow women. This article establishes the reasons that influence same-sex orientation and behaviors among women in Tanzania. It explores the self-reported push/pull reasons that ultimately leads women to same-sex behavior among sampled through individuals. Method: This is a cross-sectional descriptive and retrospective study which was conducted in Dar es Salaam between January and February, 2021. The participants of the study were WSW, proxy WSW, and women who at one time had female same-sex relationships. The study also used community members aged 18 years and above but only those who met the inclusion criteria. Data were collected through qualitative in-depth interviews, focus group discussions, interviews, and life stories. All the data generated through the study were analyzed thematically. Results: The findings indicate that women who practice same-sex behavior believe that their behavior occurs naturally through biological reasons. Some of them attribute earlier negative experiences with men as a trigger to opt out of heterosexual sex. Most participants also cited past unpleasant sexual experiences with men such as rape, being emotionally detached from men as factors that lead to developing desires to have sex with fellow women. Conclusion: There are biological and social-economic factors that lead women to practice same-sex behaviors. Women, who are born with male attributes become sexually unattracted to males, opt to engage in same-sex practices because of displeasure from having sex with men. Further, economic hardships in societies force women to engage in same-sex practices through peers who are financially well-off and are searching for peers to exploit sexually. Research should focus on investigating peer influence and social media’s effects on women’s decision to engage in same sex practices.","PeriodicalId":73820,"journal":{"name":"Journal of medical research and surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47090788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Reconstructions around inguinoscrotal region has been a challenging task owing to complex anatomy. There are variety of flap options available for reconstruction of Inguinoscrotal region. Our study was done to evaluate the use of pedicled anterolateral thigh flap for reconstruction of defects around inguinoscrotal regions. Methodology: In this study a total of 18 patients with various types of defects around inguinoscrotal region were evaluated. The etiology of defects included trauma (𝑛=6), infection (𝑛=8), malignancy (𝑛=2) and burn (𝑛=2). Patients were evaluated in terms of viability of the flap, number of perforators included, pedicled length and flap dimensions and donor site morbidity. Results: All flaps were survived well except 1 flap develop venous congestion in immediate post operative period due to tension over vascular pedicle which was managed by increasing pedicle length. 2 patients had developed partial loss of the skin graft at the donor site which got healed secondarily in due course. All patients were followed up for an average period of 6 months, ranging from 1 to 12 months. Donor site morbidity was minimal. Conclusion: Pedicled ALT flap is a versatile, reliable flap, with wide arc of rotation which makes it as an ideal flap for the coverage of defects around inguinoscrotal region.
{"title":"Pedicled Anterolateral Thigh Flap As A Workhourse Flap for Reconstruction of Inguino-Scrotal Defects","authors":"Mukesh Sharma, N. Kumar, V. Babu","doi":"10.52916/jmrs21s103","DOIUrl":"https://doi.org/10.52916/jmrs21s103","url":null,"abstract":"Background: Reconstructions around inguinoscrotal region has been a challenging task owing to complex anatomy. There are variety of flap options available for reconstruction of Inguinoscrotal region. Our study was done to evaluate the use of pedicled anterolateral thigh flap for reconstruction of defects around inguinoscrotal regions. Methodology: In this study a total of 18 patients with various types of defects around inguinoscrotal region were evaluated. The etiology of defects included trauma (𝑛=6), infection (𝑛=8), malignancy (𝑛=2) and burn (𝑛=2). Patients were evaluated in terms of viability of the flap, number of perforators included, pedicled length and flap dimensions and donor site morbidity. Results: All flaps were survived well except 1 flap develop venous congestion in immediate post operative period due to tension over vascular pedicle which was managed by increasing pedicle length. 2 patients had developed partial loss of the skin graft at the donor site which got healed secondarily in due course. All patients were followed up for an average period of 6 months, ranging from 1 to 12 months. Donor site morbidity was minimal. Conclusion: Pedicled ALT flap is a versatile, reliable flap, with wide arc of rotation which makes it as an ideal flap for the coverage of defects around inguinoscrotal region.","PeriodicalId":73820,"journal":{"name":"Journal of medical research and surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45950206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
We live with solar radiation from birth to death and have since the emergence of life on earth. Why then does skin cancer diagnosis remain so disturbingly high in Australia? Part of the problem is the majority of the population are of Northern European ancestry. Moving closer to the equator on mass we have carried with us a polymorphic melanocortin receptor gene on our melanocytes responsible for an incomplete tanning response. We attempt to protect ourselves with clothing and creams or remain indoors but this does not seem to be stemming the tide. Occupation, recreation or both drive us outside and into the sun. We need to be more successful at negotiating the potentially harmful effects by relooking at solar radiation and instead of focusing on the most harmful wavelengths look at the overall effect of the whole spectrum. We also need to re-examine our behaviour and exposure patterns. Prolonged periods indoors under artificial light punctuated with short bursts of intense irradiation is maladaptive. Creams aim to block the ultraviolet component, ignoring 90% of solar photons, the protective effect is incomplete, yet their use encourages more prolonged exposure. Protective behaviours are necessary for the most sensitive skin types but they are still at risk. For the rest of the population evolutionarily developed natural protective mechanisms can be employed. Regular moderate sun exposure, below the burn threshold, ideally aimed at early morning or late afternoon. Augmented with clothing, hats and creams with an appreciation of the incomplete protective effect of these measures.
{"title":"The Influence of Non-UV Wavelengths of Light on Skin: What Constitutes a Healthy Level of Exposure Particularly in Relation to Melanoma?","authors":"D. Smith","doi":"10.52916/jmrs21s104","DOIUrl":"https://doi.org/10.52916/jmrs21s104","url":null,"abstract":"We live with solar radiation from birth to death and have since the emergence of life on earth. Why then does skin cancer diagnosis remain so disturbingly high in Australia? Part of the problem is the majority of the population are of Northern European ancestry. Moving closer to the equator on mass we have carried with us a polymorphic melanocortin receptor gene on our melanocytes responsible for an incomplete tanning response. We attempt to protect ourselves with clothing and creams or remain indoors but this does not seem to be stemming the tide. Occupation, recreation or both drive us outside and into the sun. We need to be more successful at negotiating the potentially harmful effects by relooking at solar radiation and instead of focusing on the most harmful wavelengths look at the overall effect of the whole spectrum. We also need to re-examine our behaviour and exposure patterns. Prolonged periods indoors under artificial light punctuated with short bursts of intense irradiation is maladaptive. Creams aim to block the ultraviolet component, ignoring 90% of solar photons, the protective effect is incomplete, yet their use encourages more prolonged exposure. Protective behaviours are necessary for the most sensitive skin types but they are still at risk. For the rest of the population evolutionarily developed natural protective mechanisms can be employed. Regular moderate sun exposure, below the burn threshold, ideally aimed at early morning or late afternoon. Augmented with clothing, hats and creams with an appreciation of the incomplete protective effect of these measures.","PeriodicalId":73820,"journal":{"name":"Journal of medical research and surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48845493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lina May Osit, Joseph Joven Gammad, Olivia C. Flores
Introduction: Pain after laparoscopic cholecystectomy is complex in nature and several methods are performed to control it. Transversus Abdominis Plane (TAP) block has been used for postoperative pain for some abdominal surgeries. This study was designed to determine the analgesic efficacy of bilateral TAP block for patients undergoing Laparoscopic Cholecystectomy. Methods: Forty-two patients were randomized into 2 groups. Group 1 received TAP block using bupivacaine 0.25% (n=21), and group 2 received TAP block using saline. Before extubation, blocks were performed bilaterally. Tramadol IV was given for breakthrough pain for the first 24 hours. Pain scores using the Visual Analog Scale (VAS) at 0, 1, 2, 4 ,8 ,12, 24 hour-intervals, number of patient demand for Tramadol and patient satisfaction were collected. Results: Patients in the control group have higher VAS scores both during rest and on movement. However, pain was significantly reduced only on the 2nd hour at rest and on the 1st to 4th hours on movement among patients who received Bupivacaine 0.25% on TAP block. Furthermore, there was no significant difference in the requirement for rescue analgesics (p=0.1160) and the satisfaction rate (p=0.2849) between the two groups. Conclusion: TAP block is safe and improved postoperative analgesia in patients receiving laparoscopic cholecystectomy. But its additional analgesic effect in the presence of a dynamic multimodal pain-control regimen is probably rather small and need further investigation in laparoscopic cholecystectomy.
{"title":"The Efficacy of Ultrasound-Guided Bilateral Transversus Abdominal Plane (TAP) Block in Decreasing the Pain After Laparoscopic Cholecystectomy: A Randomized Clinical Trial","authors":"Lina May Osit, Joseph Joven Gammad, Olivia C. Flores","doi":"10.52916/jmrs214058","DOIUrl":"https://doi.org/10.52916/jmrs214058","url":null,"abstract":"Introduction: Pain after laparoscopic cholecystectomy is complex in nature and several methods are performed to control it. Transversus Abdominis Plane (TAP) block has been used for postoperative pain for some abdominal surgeries. This study was designed to determine the analgesic efficacy of bilateral TAP block for patients undergoing Laparoscopic Cholecystectomy. Methods: Forty-two patients were randomized into 2 groups. Group 1 received TAP block using bupivacaine 0.25% (n=21), and group 2 received TAP block using saline. Before extubation, blocks were performed bilaterally. Tramadol IV was given for breakthrough pain for the first 24 hours. Pain scores using the Visual Analog Scale (VAS) at 0, 1, 2, 4 ,8 ,12, 24 hour-intervals, number of patient demand for Tramadol and patient satisfaction were collected. Results: Patients in the control group have higher VAS scores both during rest and on movement. However, pain was significantly reduced only on the 2nd hour at rest and on the 1st to 4th hours on movement among patients who received Bupivacaine 0.25% on TAP block. Furthermore, there was no significant difference in the requirement for rescue analgesics (p=0.1160) and the satisfaction rate (p=0.2849) between the two groups. Conclusion: TAP block is safe and improved postoperative analgesia in patients receiving laparoscopic cholecystectomy. But its additional analgesic effect in the presence of a dynamic multimodal pain-control regimen is probably rather small and need further investigation in laparoscopic cholecystectomy.","PeriodicalId":73820,"journal":{"name":"Journal of medical research and surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45923730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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