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The Incidence of Methicillin Resistance Staphylococcus aureus in Diabetic Septic Foot 糖尿病脓毒性足耐甲氧西林金黄色葡萄球菌的发生率
Pub Date : 2019-01-01 DOI: 10.35248/2329-891X.19.7.333
M. O. Mahjoob, A. E. Abdalla, Haitham E Elawad, A. Abdulla, Saffa Omer Altayeb, Umalhassan Hashim Abdalla
Background: Foot infection is the most common problem in a person with diabetes. Infection in these patients is difficult to treat because these individuals have impaired microvascular supply, Which limits the access of phagocytic cell in the infected area and result in poor concentration of antibody in the infected tissue. Staphylococcus aureus is a major cause of potentially life-threatening infection which was acquired in the health care and community setting. These microorganisms have developed resistance against most classes of antibacterial agent as indicated by a dramatic increase in the number of healthcare-associated infection due to methicillin resistance S. aureus, which become endemic in hospitals worldwide. Methods: All collected samples were cultured directly on the blood and chocolate agar to primary isolation, then purified by several subcultures from a single well-isolated colony. Identification of isolated bacteria depends on gram reactions, organism morphology, colonial morphology in different media and biochemical tests-catalase test, coagulase test, DNase test, mannitol fermentation test, and VP test. The antimicrobial test was carried by disc diffusion method Kirby-Bauer method on Muller and Hinton media to several single antibiotic discs-Vancomycin, cloxacillin, Tobracillin, Ciprofloxacin, and Ceftriaxone. The inhibition zone was measured by ruler in millimeter the compared with incorporated chart. Results: A total of 50 diabetic patients with wound infection were including S. aureus n:20, 40% and other pathogens n:30,60%. Frequency of male was 43,86% while 7,14% were female. All patient were classified into two groups of age, one (35-55) with moderate frequency n:20, 40% and another age group (56-90) with the highest frequency n:30,60%. All isolated S. aureus were resisted cloxacillin while sensitive to vancomycin, 60% of them resist tobracillin 40% were sensitive and 10% resist ciprofloxacin 90% were sensitive, 25% were resisted ceftriaxone 75% were sensitive. Conclusion: MRSA is highly 40% prevalent among populations of S. aureus isolated from surgical site infection in Khartoum state. This study discusses the link between MRSA acquisition factors like age, sex, occupation, ethnicity, geographical location, hospitalization, antibiotic use, surgery and distinction community-acquired MRSA and hospital-acquired MRSA.
背景:足部感染是糖尿病患者最常见的问题。这些患者的感染很难治疗,因为这些个体的微血管供应受损,这限制了吞噬细胞进入感染区域,导致感染组织中抗体浓度低。金黄色葡萄球菌是在卫生保健和社区环境中获得的潜在危及生命的感染的主要原因。这些微生物已经对大多数种类的抗菌剂产生了耐药性,这表明,由于耐甲氧西林金黄色葡萄球菌引起的卫生保健相关感染数量急剧增加,这在世界各地的医院中成为地方性疾病。方法:所有收集的样品直接在血琼脂和巧克力琼脂上培养至初分离,然后从单个分离良好的菌落中进行多次传代纯化。分离细菌的鉴定取决于革兰氏反应、微生物形态、不同培养基中的菌落形态和生化试验——过氧化氢酶试验、凝固酶试验、dna酶试验、甘露醇发酵试验和VP试验。采用圆盘扩散法Kirby-Bauer法在Muller和Hinton培养基上对万古霉素、氯西林、妥布西林、环丙沙星、头孢曲松等单药圆盘进行抗菌试验。用尺测量抑制带,单位为毫米,并与合并图进行比较。结果:50例糖尿病患者并发伤口感染,其中金黄色葡萄球菌占20.40%,其他病原菌占30.60%。男性占43.86%,女性占7.14%。将所有患者分为两组年龄,一组年龄(35-55岁)为中频n: 20.40%,另一组年龄(56-90岁)为高频n: 30.60%。所有分离到的金黄色葡萄球菌对氯西林耐药,对万古霉素敏感,对布拉西林耐药60%,对40%敏感,对环丙沙星耐药10%,对头孢曲松耐药25%,对75%敏感。结论:在喀土穆州手术部位感染金黄色葡萄球菌分离人群中,MRSA的流行率高达40%。本研究探讨了MRSA获得因素如年龄、性别、职业、种族、地理位置、住院、抗生素使用、手术以及区分社区获得性MRSA和医院获得性MRSA之间的联系。
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引用次数: 0
Emergency Obstetric Care-A protocol of a Situational Analysis in the Country Context of Bangladesh 紧急产科护理——孟加拉国国家情况分析议定书
Pub Date : 2019-01-01 DOI: 10.35248/2329-891X.19.7.318
A. S. Rahman, R. Begum, Tanusree Sarkar, J. Uddin, M. Islam
Background: Despite a consistently decreasing trend, maternal and infant mortality rates still remain a challenge in Bangladesh. This shows that there is a need for constant efforts to improve accessibility and quality of maternal and child care and implement what is reflected in recent policy documents, issued by the government, which is reinforced by a number of related surveys and research studies. Aim: The goal of this analysis is to examine the current situation and needs of emergency obstetric care in Bangladesh by establishing a baseline of the availability, utilization, and quality of maternal health care services. Study design: Corporate approach will be used for this situational analysis to generate data. Data collection methods will be key informants interviews (KII) and focus group discussions (FGDs). Data will also be collated from secondary sources as for example District hospital, Demographic and Health Survey (DHS), Director General (DG) Health, Non-Governmental Organizations (NGOs) and literature review. Conclusion: In order to reduce high maternal mortality and morbidity, high utilization of EmONC is necessary. This situational analysis will project an in-depth understanding of the coverage and availability of the emergency obstetric care and also will highlight the factors facilitating and preventing the use of emergency obstetric care services in the district of Sylhet in Bangladesh and it is anticipated that the results from this analysis will contribute to an evidence-based refinement and planning of even more effective strategies for further reducing maternal mortality.
背景:尽管产妇和婴儿死亡率呈持续下降趋势,但在孟加拉国仍然是一个挑战。这表明,需要不断努力提高妇幼保健的可及性和质量,并实施政府最近发布的政策文件中所反映的内容,许多相关调查和研究也加强了这一点。目的:本分析的目的是通过建立产妇保健服务的可得性、利用率和质量的基线,审查孟加拉国紧急产科护理的现状和需求。研究设计:将采用企业方法进行情境分析以生成数据。数据收集方法将是关键举报人访谈(KII)和焦点小组讨论(fgd)。还将从二级来源整理数据,例如地区医院、人口与健康调查、卫生总干事、非政府组织和文献审查。结论:为降低孕产妇高死亡率和发病率,应大力推广应用EmONC。这一情况分析将有助于深入了解紧急产科护理的覆盖范围和提供情况,还将强调在孟加拉国锡尔赫特区促进和阻止使用紧急产科护理服务的因素,预计这一分析的结果将有助于以证据为基础改进和规划更有效的战略,以进一步降低孕产妇死亡率。
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引用次数: 0
Effect of Seasonal Malaria Chemoprevention and Data Management in Health Facilities in Three Study LGAs of Adamawa State, Nigeria 尼日利亚阿达马瓦州三个研究地区卫生机构季节性疟疾化学预防和数据管理效果
Pub Date : 2019-01-01 DOI: 10.35248/2329-891X.19.7.337
I. Nglass, Lynda Ozor, O. Olotu, A. Momoh, Chima E Onuekwe, Collins Owili
Malaria remains a leading cause of ill health in Africa and Nigeria. From world malaria report, 2018 53 million annual cases in Nigeria (1 in 4 persons), contributing 25% global burden and 53% of cases in West Africa. In Nigeria alone, 81,640 deaths are recorded annually (9 deaths per hour), which accounts for 19% global malaria deaths (1 in 5 global malaria deaths) and 45% malaria deaths in west Africa. The Nigeria Malaria Strategic Plan (NMSP) 2014-2020 has as it goal-to reduce malaria burden to pre-elimination levels and bring malaria-related mortality to zero. In North-East Nigeria, malaria transmission is perennial with a marked seasonal peak from July to November each year. Since malaria is highly endemic in the north-east, increasing the burden on health resources and elevating the risk of morbidity and mortality among the affected population, particularly children under five who are one of the vulnerable groups, Seasonal Mass Chemo-Prevention (SMC) during the rainy season to reduce morbidity and mortality in emergency settings was deployed in 2018 and the results were enormous 6.5% reduction in fever cases and confirmed malaria, when compared with previous years in children under five who benefited from SMC as obtained from the study of effect of SMC on malaria morbidity conducted in Adamawa State in 2018. To achieve a better impact on malaria control, a combination of preventive measures (robust surveillance, indoor residual spray, using insecticide-treated nets), effective case management and improved capacity of personnel is recommended.
疟疾仍然是非洲和尼日利亚健康不良的主要原因。根据《世界疟疾报告》,2018年尼日利亚每年发生5300万例病例(四分之一),占全球负担的25%,占西非病例的53%。仅在尼日利亚,每年就有81,640人死亡(每小时9人死亡),占全球疟疾死亡人数的19%(全球疟疾死亡人数的五分之一),占西非疟疾死亡人数的45%。尼日利亚2014-2020年疟疾战略计划(NMSP)的目标是将疟疾负担降低到消除前水平,并将疟疾相关死亡率降至零。在尼日利亚东北部,疟疾传播是多年性的,每年7月至11月为明显的季节性高峰。由于疟疾在东北部高度流行,增加了卫生资源的负担,并增加了受影响人群(特别是弱势群体之一的五岁以下儿童)发病率和死亡率的风险,因此,2018年在雨季部署了季节性大规模化学预防(SMC),以降低紧急情况下的发病率和死亡率,结果是发烧病例和确诊疟疾大幅减少6.5%。根据2018年在阿达马瓦州进行的关于SMC对疟疾发病率影响的研究得出的结论,与往年相比,从SMC受益的五岁以下儿童的死亡率。为了更好地控制疟疾,建议综合采取预防措施(强有力的监测、室内残留喷雾、使用驱虫蚊帐)、有效的病例管理和提高人员能力。
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引用次数: 2
A Situational Analysis of Screening and Treatment of TB in Pregnant Women across 5 Countries 5个国家孕妇结核病筛查和治疗情况分析
Pub Date : 2019-01-01 DOI: 10.35248/2329-891X.19.7.332
H. Almossawi, N. Kak, Amy Studenic, Alex, E. Moran, Colleen F Longacre, S. Kheang, P. Daru, Esty Febriani, Cecile Lagrosa, Carmina Aquino, T. Htay
Background: Tuberculosis (TB) is the third leading cause of death among women of reproductive age, and undiagnosed TB among pregnant women can result in poor outcomes for both women and their children. Therefore, it is essential for National Tuberculosis Programs (NTPs) to strengthen their policies and guidelines addressing TB in pregnant women and adopt more efficient screening practices. The purpose of this situational analysis is to identify key approaches to addressing TB in pregnancy and to identify barriers and recommendations for the integration of TB and Antenatal Care (ANC) services. Methods: We conducted an initial desk review of the existing literature and recommendations from international organizations on global strategies to address TB among pregnant women. We developed a multi-country survey to gather information on current practices regarding TB screening and treatment among pregnant women as well as barriers to integration of TB services with ANC services. Results: We received survey responses from five countries (Bangladesh, Indonesia, Myanmar, the Philippines, and Vietnam). Only Myanmar had fully integrated TB and ANC services. While respondents from all countries identified the potential benefits of TB/ANC service integration, the most commonly identified barriers to implementation included lack of management capacity to supervise integrated services, inadequate staff, and lack of knowledge about TB among ANC staff. Conclusion: While countries are aware of the advantages and opportunities associated with integrating TB services into other health care services, the implementation of such integration remains a challenge. Integration of services is one of the key recommendations of this study. Where services have been fully integrated, operational research is needed to evaluate its impact.
背景:结核病是育龄妇女死亡的第三大原因,孕妇中未确诊的结核病可能导致妇女及其子女的不良结局。因此,国家结核病规划(NTPs)必须加强其针对孕妇结核病的政策和指南,并采取更有效的筛查做法。本情景分析的目的是确定应对妊娠期结核病的关键方法,并确定将结核病和产前保健(ANC)服务整合的障碍和建议。方法:我们对现有文献和国际组织关于解决孕妇结核病全球战略的建议进行了初步的案头回顾。我们开展了一项多国调查,以收集有关孕妇结核病筛查和治疗的现行做法以及将结核病服务与ANC服务相结合的障碍的信息。结果:我们收到了来自五个国家(孟加拉国、印度尼西亚、缅甸、菲律宾和越南)的调查回复。只有缅甸完全整合了结核病和ANC服务。虽然来自所有国家的答复者都确定了结核病/非结核结核服务整合的潜在好处,但最常见的实施障碍包括缺乏监督综合服务的管理能力、人员不足以及非结核结核工作人员缺乏结核病知识。结论:虽然各国意识到将结核病服务纳入其他卫生保健服务的优势和机会,但实施这种整合仍然是一项挑战。服务整合是本研究的主要建议之一。在各项服务已完全整合的情况下,需要进行业务研究以评估其影响。
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引用次数: 1
Severe Acute Malnutrition (SAM) Evaluation of Associated Risk Factors, Screening Tools, and Therapeutic Management among South Sudanese Children Age 6 南苏丹6岁儿童严重急性营养不良(SAM)相关风险因素、筛查工具和治疗管理评估
Pub Date : 2019-01-01 DOI: 10.4172/2329-891X.1000298
Amanya Jacob Kasio Iboyi, L. Zha
Severe Acute Malnutrition (SAM) is a major silent killer among children under five years of age, in low resources settings. It’s also being regarded as a disease of hungry communities. Therefore, to assess and classify an individual nutritional status under SAM is by anthropometry that determines body measurement. Measurable variables, age, sex, weight, height and Mid-Upper Arm-Circumference (MUAC) for children 6-59 months. SAM characterized with visible wasting and bilateral edema, in infants <6 months. However, social criteria like the absence of a mother or inadequacy of breastfeeding predict nutritional risk. Once more, SAM in U5 assessed by nutritional indices of Weight-For-Height (WFH), MUAC, and bilateral edema. Children 5-19 years BMI-for-age plus clinical signs are used. MUAC preferable during pregnancy. WHO Growth Standards of 2007 suggested over NCHS 1978. Nutrition indices in Z-scores opposed to median percentage. Median off use in classifying individual’s nutritional status. Methods and protocols for assessment of children 6-59 months are more developed than for other age. Therefore, best practice to produce functional outcomes is needed. The level of malnutrition at admission phase influences hospitals stay. Evidence suggests that malnutrition is more frequent and severe among males than females. Implications, no special consideration in severe acute malnutrition admitted in a critical phase”. Protocols to discharge patients upon recovery needs harmonization. MUAC misdiagnose Kwashiorkor children due to fluid retention but remains a reliable tool. Ready to Use Therapeutic Food (RUTF) used for management of SAM. The study aimed to evaluate the effectiveness of screening tools, therapeutic interventions and shed light on the risk factors associated with SAM. A later effect includes but not limited to mental retardation, poor school performance, and low self-esteem.
在资源匮乏的环境中,严重急性营养不良是五岁以下儿童的主要无声杀手。它也被认为是饥饿社区的疾病。因此,在SAM下评估和分类个人营养状况是通过确定身体测量的人体测量学。6-59个月儿童的年龄、性别、体重、身高和中上臂围(MUAC)的可测量变量。SAM的特点是明显消瘦和双侧水肿,在婴儿<6个月。然而,缺少母亲或母乳喂养不足等社会标准预示着营养风险。同样,通过体重身高(WFH)、MUAC和双侧水肿等营养指标评估U5的SAM。使用5-19岁儿童的年龄bmi加上临床症状。怀孕期间最好使用MUAC。2007年世界卫生组织生长标准高于1978年国家卫生标准。z分数中的营养指数相对于中位数百分比。中位数差用于分类个人营养状况。6-59个月儿童的评估方法和方案比其他年龄的儿童更发达。因此,需要最佳实践来产生功能性结果。入院期营养不良程度影响住院时间。有证据表明,男性营养不良比女性更为频繁和严重。影响,没有特别考虑严重急性营养不良在关键阶段承认”。病人康复出院的方案需要统一。由于液体潴留,MUAC误诊了夸希奥尔科儿童,但仍然是一个可靠的工具。即食治疗食品(RUTF)用于管理SAM。该研究旨在评估筛查工具、治疗干预措施的有效性,并阐明与SAM相关的风险因素。后来的影响包括但不限于智力迟钝,学习成绩差,自卑。
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引用次数: 3
Brucellosis in Saudi Arabia: Review of Literature and Epidemiology 布鲁氏菌病在沙特阿拉伯:文献综述和流行病学
Pub Date : 2019-01-01 DOI: 10.4172/2329-891X.1000304
Hassan Ghazi Bakheet, H. Alnakhli
Brucellosis is a zoonotic disease, which is endemic in Saudi Arabia. It’s an infectious systematic disease that can affect any organ, with no specific symptom to this disease. The diagnosis of Brucellosis depends mainly on the investigations. Treatment of Brucellosis requires an extensive course of antibiotics used for at least 6 weeks to avoid relapse or recurrence. This disease is caused by Brucella spp. It’s considered to be a major problem in endemic countries, due to poor hygiene, and unprotected contact with animals. Brucellosis is a challenging disease diagnose since there are no special symptoms for this disease. The incidence of Brucellosis globally is up to 500,000 people infected annually therefore, it’s the most widespread zoonotic disease. There are some rare cases of Brucellosis in the Kingdom of Saudi Arabia. Several laboratory tests are used to confirm the diagnosis, and the most common laboratory test used in Saudi Arabia is the SAT. Preventing brucellosis depends on contact isolation from infected beings, safety cautions in labs, Pasteurization of milk, and controlling of vectors.
布鲁氏菌病是一种人畜共患疾病,在沙特阿拉伯流行。这是一种传染性的系统性疾病,可以影响任何器官,没有特定的症状。布鲁氏菌病的诊断主要依靠调查。治疗布鲁氏菌病需要广泛使用抗生素至少6周,以避免复发或复发。这种疾病是由布鲁氏菌引起的,由于卫生条件差和与动物无保护接触,它被认为是流行国家的一个主要问题。布鲁氏菌病是一种具有挑战性的疾病诊断,因为这种疾病没有特殊症状。布鲁氏菌病的全球发病率每年高达50万人感染,因此,它是最广泛的人畜共患疾病。在沙特阿拉伯王国有一些罕见的布鲁氏菌病病例。用于确认诊断的实验室检测有几种,沙特阿拉伯最常用的实验室检测是SAT。预防布鲁氏菌病取决于与感染者隔离接触、实验室安全注意事项、牛奶巴氏消毒和媒介控制。
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引用次数: 10
The Prevalence of Urinary Schistosomiasis among the Abo-Matariq Population, East Darfur State, Sudan 苏丹东达尔富尔州Abo-Matariq人群尿路血吸虫病患病率
Pub Date : 2019-01-01 DOI: 10.35248/2329-891X.19.7.319
Yousif M Ballal, Husameldin A Bakhit, Mohammed B. Ahmed, M. Suliman, Aisha Aa Lsadig, Nabig A Gasoum, Monadel M Zain Alabeden
This cross-sectional study was conducted in Abo-Matariq area in East Darfur state on 570 individuals (370 males and 200 females) to determine the prevalence rate of Schistosoma haematobium and to evaluate two diagnostic methods (sedimentation and filtration techniques). The study was carried out during the period between February 2018-April 2018, urine samples were taken from the subjects. The study showed that the overall prevalence rate of infection was 20.2%, all positive cases (115) out of 570 were detected by using urine sedimentation and filtration techniques. Males have reported a higher rate of infection than females (15.8% and 4.4% respectively). The highest infection rate of 15.6% was reported among the age group of 11-20 years, while there was no positive case reported among the 31-40 and over 40 years age groups. The study showed that among 115 positive cases, 107 (18.8%) had direct contact with water and 8 (1.4%) had no contact with water. Also, the study showed that among 115 positive cases 100 (17.6%) had haematuria in their urine while 15 (2.6%) had no haematuria in their urine. The study showed an equal detection rate for both techniques used.
本横断面研究在东达尔富尔州的Abo-Matariq地区对570名个体(370名男性和200名女性)进行,以确定血血吸虫的患病率,并评估两种诊断方法(沉淀和过滤技术)。该研究于2018年2月至2018年4月期间进行,从受试者身上采集了尿液样本。研究结果显示,总感染率为20.2%,570例阳性病例(115例)均采用尿沉淀和过滤技术检出。男性报告的感染率高于女性(分别为15.8%和4.4%)。11 ~ 20岁年龄组感染率最高,为15.6%,31 ~ 40岁及40岁以上年龄组无阳性病例报告。研究结果显示,115例阳性病例中,有直接接触水的107例(18.8%),无接触水的8例(1.4%)。此外,该研究显示,在115例阳性病例中,100例(17.6%)尿中有血尿,15例(2.6%)尿中没有血尿。研究表明,两种技术的检出率相同。
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引用次数: 0
Bidirectional Screening of Diabetes Mellitus and Tuberculosis in Cambodia 柬埔寨糖尿病和肺结核的双向筛查
Pub Date : 2019-01-01 DOI: 10.35248/2329-891x.19.7.326
S. Kheang, Huot Theang, K. K. Eam, M. T. Eang, S. Kong, Chhun Loun, Aida Olkkonen, H. Almossawi, N. Kak
Background: Cambodia has a high burden of Tuberculosis (TB) with an incidence rate of 326 per 100,000 population in 2018 and rapidly increasing rates of Diabetes Mellitus (DM) with prevalence rate 9.6% in 2016. The introduction of the first national guidelines for the management of TB/DM co-morbidity in 2014 has resulted in the introduction of coordinated service delivery. Objective: This study aimed to assess the performance and the results of bidirectional TB/DM screening, diagnosis of co-morbidity, and enrollment in treatment in 7 health operational districts in 5 provinces in Cambodia. Methods: The retrospective study reviewed patient records of 6,463 DM patients and 8,403 TB patients who received treatment between July 2016 and February 2019 in 7 referral hospitals and 113 health centers. Results: Forty percent of DM patients were screened for TB, and 55% of TB patients were screened for DM. Of the screened DM patients, 4.6% were diagnosed with TB. Of screened TB patients, 3.7% were diagnosed with DM. All DM patients diagnosed with TB were enrolled in TB treatment and 95% of TB patients diagnosed with DM began receiving treatment for DM. Conclusion: This is the first study examining TB/DM co-morbidity and coordinated service delivery in Cambodia. The gaps in the performance of bidirectional screening suggest areas for further intervention. To increase the rate of bidirectional screening, provider compliance with standards needs to be improved by strengthening providers competencies. Strengthened data collection and reporting systems will also contribute to increasing provider accountability. Secondly, the current structure of TB and DM service delivery with TB services only available from the public sector and public DM services only available at the referral level creates a challenging environment for effective referrals and coordinated care and should be reconsidered. In addition to improved coordination between the public and private sectors, expansion of public DM services to health centers and to the community level warrants exploration. Finally, the increased focus needs to be given to addressing the high levels of pre-diabetes. Cambodia has a limited window of opportunity to build capacity and develop systems to effectively manage TB/DM co-morbidity.
背景:柬埔寨结核病(TB)负担高,2018年每10万人中有326人发病,糖尿病(DM)发病率迅速上升,2016年患病率为9.6%。2014年推出了首个国家结核病/糖尿病合并发病管理指南,从而引入了协调一致的服务提供。目的:本研究旨在评估柬埔寨5个省7个卫生业务区双向结核病/糖尿病筛查、合并症诊断和治疗入组的绩效和结果。方法:回顾性研究回顾了2016年7月至2019年2月在7家转诊医院和113家卫生中心接受治疗的6463例糖尿病患者和8403例结核病患者的病历。结果:40%的糖尿病患者接受了结核病筛查,55%的结核病患者接受了糖尿病筛查。在筛查的糖尿病患者中,4.6%被诊断为结核病。在筛查的结核病患者中,3.7%被诊断为糖尿病。所有被诊断为结核病的糖尿病患者都参加了结核病治疗,95%被诊断为糖尿病的结核病患者开始接受糖尿病治疗。结论:这是柬埔寨首次检查结核病/糖尿病合并症和协调服务提供的研究。双向筛查表现上的差距表明了进一步干预的领域。为了提高双向筛查率,需要通过加强提供者的能力来改善提供者对标准的遵守情况。加强数据收集和报告系统也将有助于提高提供者的问责制。第二,目前的结核病和糖尿病服务提供结构——结核病服务仅由公共部门提供,而公共糖尿病服务仅在转诊层面提供——为有效转诊和协调治疗创造了一个具有挑战性的环境,应予以重新考虑。除了改善公共和私营部门之间的协调外,还应探索将公共医疗保健服务扩大到保健中心和社区一级。最后,需要更多地关注解决高水平的前驱糖尿病。柬埔寨在建设能力和开发有效管理结核病/糖尿病合并症的系统方面机会有限。
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引用次数: 3
Knowledge and Practice of Sneeze and Cough Etiquettes among Participants in A Randomized Study in Ekiti-State, South-Western Nigeria 在尼日利亚西南部埃基蒂州的一项随机研究中,参与者对打喷嚏和咳嗽礼仪的知识和实践
Pub Date : 2019-01-01 DOI: 10.35248/2329-891X.19.7.335
Olajuyin Oa, Olajide Tg, Ogunboyo Of, Olajuyin Ab, Olajuyin Aa, Deji Sa
Background: Indiscriminate sneezing and coughing with infectious runny nose pose threats to public health. In this study, we investigate knowledge and practice of sneeze and cough etiquettes among residents in Ekiti-State, South- Western Nigeria. Objective: To sensitize the public on the roles of sneeze and cough etiquettes in the prevention the spread of infectious respiratory diseases. Methodology: A prospective, cross-sectional, randomized study of respondents in Ekiti State was conducted. Results: In all, 395 participants were studied. Of this number, 228 (57.7%) sneeze or cough into air without a cover on their nose or mouth, 82 (20.7%) into handkerchiefs, 20 (5.1%) into tissue, 22 (5.6%) into bare hand, 5 (1.3%) into sleeve or crook of elbow and 38 (9.6%) use a combination of methods. The proportion of respondents that wash hands or handkerchief soon after clean-up of the runny nose was only 38%. There was an inverse relationship between education attainment and hospital care of runny nose Conclusion: This study shows that the majority (57.7%) of the respondents sneeze or cough into air without a cover on the nose or mouth. Only 1.3% of the respondents sneezes or coughs into sleeve or crook of the elbow which is the most acceptable form of hygiene etiquette. The proportion of respondents that wash hands or handkerchief soon after a clean-up of runny nose was quite small. Education has no comparative advantage over illiteracy in the uptake of treatment of runny nose. We, therefore, recommend that the public must be educated on the best sneeze, cough and respiratory hygiene etiquettes irrespective of their educational attainment.
背景:不分青红皂白地打喷嚏和咳嗽并伴有传染性流鼻涕对公众健康构成威胁。在这项研究中,我们调查了尼日利亚西南部埃基蒂州居民的打喷嚏和咳嗽礼仪的知识和实践。目的:提高公众对打喷嚏和咳嗽礼仪在预防呼吸道传染病传播中的作用的认识。方法:对埃基蒂州的受访者进行了前瞻性、横断面、随机研究。结果:共有395名参与者被研究。其中,228人(57.7%)在没有鼻或口盖的情况下对着空气打喷嚏或咳嗽,82人(20.7%)对着手帕打喷嚏或咳嗽,20人(5.1%)对着纸巾打喷嚏或咳嗽,22人(5.6%)对着徒手打喷嚏或咳嗽,5人(1.3%)对着袖子或肘部打喷嚏或咳嗽,38人(9.6%)同时使用这些方法。在流鼻涕后立即洗手或用手帕洗手的受访者比例只有38%。结论:受教育程度与医院对流鼻涕的护理呈负相关关系,绝大多数(57.7%)的调查对象打喷嚏或咳嗽时不带鼻盖或口盖。只有1.3%的受访者对着袖子或肘部打喷嚏或咳嗽,这是最可接受的卫生礼仪。在流鼻涕后立即洗手或用手帕洗手的受访者比例相当小。在接受流鼻涕治疗方面,受教育的人与不识字的人相比没有比较优势。因此,我们建议市民不论受教育程度如何,都必须接受有关打喷嚏、咳嗽及呼吸道卫生礼仪的教育。
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引用次数: 0
Antibody and P. falciparum Parasites Profiles during Clinical Malaria Episodes Following Artemisinin-Based Combination Therapy in Burkina Faso 布基纳法索以青蒿素为基础的联合治疗后临床疟疾发作期间的抗体和恶性疟原虫谱
Pub Date : 2019-01-01 DOI: 10.35248/2329-891X.19.7.313
Fatimata Thiombiano, S. M. Ouattara, A. Coulibaly, G. Sanou, M. Kabore, A. Diarra, I. Soulama, Y. Traoré, S. Sirima, I. Nebie’
Background: Artemisinin-based Combination Therapies (ACTS) are the first recommended drug for uncomplicated malaria treatment in many endemic countries. They are responsible for rapid parasites clearance and in reducing fever. Artemisinin has been found to have an immunosuppressive effect in animal’s models. In the present study, we assessed the effect of ACTs on malaria antigens specific antibodies production during subsequent malaria episodes in a population living in malaria hyperendemic area. Methods: In 2012, 371 patients with, presenting uncomplicated clinical malaria aged over 6 months and adults were recruited and allocated to receive ACTs and follow up for 2 years. Antibodies titers against three P. falciparum blood stage malaria vaccine candidates (MSP3, GLURP R0, and GLURP R2) were measured by ELISA during subsequent malaria episodes. Results: Antibody concentration increased during subsequent malaria episodes for GLURP R0, and this was statistically significant. IgG to all tested antigens increased with age and this trend was maintained over all episodes. Conclusion: Asexual P. falciparum densities were showing different trends and immune responses against certain erythrocytic antigens were boosted during subsequent malaria episodes.
背景:在许多疟疾流行国家,以青蒿素为基础的联合疗法(ACTS)是用于简单疟疾治疗的首选推荐药物。它们负责快速清除寄生虫和退烧。在动物模型中发现青蒿素具有免疫抑制作用。在本研究中,我们评估了ACTs对生活在疟疾高流行地区人群随后疟疾发作期间疟疾抗原特异性抗体产生的影响。方法:2012年招募371例6个月以上无并发症的临床疟疾患者和成人,给予联合治疗,随访2年。在随后的疟疾发作期间,用ELISA测定了三种恶性疟原虫血期疟疾候选疫苗(MSP3、GLURP R0和GLURP R2)的抗体滴度。结果:GLURP R0抗体浓度在随后的疟疾发作中升高,且具有统计学意义。所有检测抗原的IgG随年龄的增长而增加,这一趋势在所有事件中都保持不变。结论:在随后的疟疾发作中,无性恶性疟原虫密度表现出不同的趋势,对某些红细胞抗原的免疫反应增强。
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引用次数: 0
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Journal of tropical diseases & public health
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