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ELSMOR - towards European Licensing of Small Modular Reactors: Methodology recommendations for light-water small modular reactors safety assessment. ELSMOR - 走向欧洲小型模块化反应堆许可证制度:轻水小型模块化反应堆安全评估方法建议。
Pub Date : 2024-10-14 eCollection Date: 2023-01-01 DOI: 10.12688/openreseurope.16360.2
Sylvain Lansou, Luca Ammirabile, Nikolai Bakouta, Jeremy Bittan, Sebastian Buchholz, Jean-Yves Brandelet, Etienne Courtin, Frans Davelaar, Stanislav Dombrovsky, Jean-Baptiste Droin, Sophie Ehster-Vignoud, Houda Hamama, Atte Helminen, Thorsten Hollands, Andriy Iskra, Sebastien Israel, Stefano Lorenzi, Liviusz Lovasz, Valerie Paulus, Isabelle Pichancourt, Joachim Miss, Thuy Nguyen, Antti Rantakaulio, Federico Rocchi, Juan-Carlos de-la-Rosa-Blul, Marco Ricotti, Armin Seubert, Oleksandr Sevbo, Stanislav Sholomitsky, Olli Suurnäkki, Marton Szogradi, Ville Tulkki, Andreas Wielenberg

Decarbonization of energy production is key in today's societies and nuclear energy holds an essential place in this prospect. Besides heavy-duty electricity production, other industrial and communal needs could be served by integrating novel nuclear energy production systems, among which are low-power nuclear devices, like small modular reactors (SMRs). The ELSMOR (towards European Licensing of Small Modular Reactors) European project addresses this topic as an answer to the Horizon 2020 Euratom NFRP-2018-3 call. The consortium includes 15 partners from eight European countries, involving research institutes, major European nuclear companies and technical support organizations. The 3.5-year project, launched in September 2019, investigates selected safety features of light-water (LW) SMRs with focus on licensing aspects. Providing a comprehensive compliance framework that regulators can adopt and operate, the licensing process of such SMRs could be optimized, helping their deployment. In this prospect, as a result of ELSMOR's work, this article gives an overview of the specific issues that LW-SMRs may bring about in the different domains of nuclear safety, in terms of: •Methodological standpoints: safety goals, safety requirements, safety principles (defence-in-depth implementation);•Main safety functions of reactivity control, decay heat removal and confinement management;•Severe accident management;•Other safety issues particular to SMRs: use of shared systems; performing of multi-unit probabilistic safety assessment (PSA); spent fuel management, transport and disposal management. In this article, adequate methodologies are developed to deal with these issues and to help assess the safety of LW-SMRs. This work gives a precious synthesis of the safety assessment issues of LW-SMRs and of the associated methodologies developed in the context of the ELSMOR European project.

能源生产的去碳化是当今社会的关键,而核能在这一前景中占有重要地位。除重型电力生产外,其他工业和社区需求也可通过整合新型核能生产系统来满足,其中包括小型模块化反应堆(SMR)等低功率核装置。作为对地平线2020欧洲原子能共同体NFRP-2018-3号召的回应,ELSMOR(争取小型模块化反应堆的欧洲许可)欧洲项目致力于解决这一问题。该联合体包括来自 8 个欧洲国家的 15 个合作伙伴,涉及研究机构、欧洲主要核公司和技术支持组织。该项目为期 3.5 年,于 2019 年 9 月启动,调查轻水 (LW) SMR 的选定安全特性,重点关注许可方面。通过提供监管机构可以采用和操作的全面合规框架,可以优化此类 SMR 的许可流程,从而有助于其部署。在这一前景下,作为 ELSMOR 的工作成果,本文从以下方面概述了轻型 SMR 在核安全的不同领域可能带来的具体问题:-方法论观点:安全目标、安全要求、安全原则(深度防御的实施);-反应性控制、衰变热去除和封闭管理的主要安全功能;-严重事故管理;-SMRs 特有的其他安全问题:共享系统的使用;多单元概率安全评估(PSA)的执行;乏燃料管理、运输和处置管理。本文制定了适当的方法来处理这些问题,并帮助评估低温超导堆的安全性。这项工作对轻水堆安全评估问题以及在欧洲 ELSMOR 项目背景下开发的相关方法进行了宝贵的综述。
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引用次数: 0
COVID-19 and (ir)responsible (im)mobility: Reading counter-practices through Levinas and Derrida. COVID-19 和(不)负责任的(不)流动性:通过列维纳斯和德里达解读反实践。
Pub Date : 2024-10-07 eCollection Date: 2024-01-01 DOI: 10.12688/openreseurope.16686.2
Raffaela Puggioni

The COVID-19 pandemic has affected virtually all daily activities, relations and practices. People were expected to act responsibly by following social distancing, masking, sanitation and stay-home rules. The prevailing ethos of the time was that to protect others, one must first protect oneself. By examining the creative modalities through which (a few) people in Paris circumvented mobility restrictions to help and support those in need, this article investigates the relation between (im)mobility and (ir)responsibility. Is mobility, during a time of forced immobility, an irresponsible act? What does it mean to act responsibly during a life-threatening emergency? Does responsibility always require complete and unequivocal compliance with extant norms, or should responsibility also be evaluated in light of the motives that inspire (unauthorised) mobility? The issue of (ir)responsible (im)mobility is scrutinised here by drawing upon the work of Emmanuel Levinas and Jacques Derrida. While the former furthers our understanding of ethical relations, the latter makes us rethink the concept of response-ability and, in particular, the aporia this concept entails. As Derrida highlights, truly ethical acts are impossible for the very reason that all ethical acts are, at the very same time, responsible towards some and irresponsible towards others.

COVID-19 大流行几乎影响了所有日常活动、关系和做法。人们被期望以负责任的方式行事,遵守社会隔离、掩盖、卫生和足不出户的规则。当时流行的风气是,要保护他人,首先要保护自己。通过研究巴黎(少数)人规避行动限制、帮助和支持需要帮助的人的创造性方式,本文探讨了(非)流动性与(非)责任之间的关系。在被迫无法行动的时期,行动是否是一种不负责任的行为?在危及生命的紧急情况下采取负责任的行动意味着什么?责任是否总是要求完全、明确地遵守现有规范,还是也应根据激发(未经授权的)流动的动机来评估责任?在此,我们借鉴埃马纽埃尔-列维纳斯和雅克-德里达的研究成果,对(不)负责任的(不)流动性问题进行了探讨。前者加深了我们对伦理关系的理解,而后者则让我们重新思考 "回应能力 "的概念,尤其是这一概念所包含的缺陷。正如德里达所强调的,真正的伦理行为是不可能的,因为所有的伦理行为都同时对某些人负责,而对另一些人不负责任。
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引用次数: 0
Linking the ECRIN Metadata Repository with the BBMRI-ERIC Directory to connect clinical studies with related biobanks and collections. 将 ECRIN 元数据储存库与 BBMRI-ERIC 目录连接起来,以便将临床研究与相关的生物库和收藏库联系起来。
Pub Date : 2024-10-07 eCollection Date: 2024-01-01 DOI: 10.12688/openreseurope.17131.2
Christian Ohmann, Steve Canham, Kurt Majcen, Vittorio Meloni, Luca Pireddu, Alessandro Sulis, Giovanni Delussu, Francesca Frexia, Petr Holub

Background: There is much value to be gained by linking clinical studies and (biosample-) collections that have been generated in the context of a clinical study. However, the linking problem is hard because usually no direct references between a clinical study and an associated collection are available.

Methods: The BBMRI-ERIC Directory and the ECRIN Metadata Repository (MDR), already include much of the information required to link clinical studies and related sample collections. In this study, we present the work performed to find and implement those links across existing corresponding records in the two systems. The linking process between MDR studies and related collections in the BBMRI-ERIC Directory started with exploring linkage in both directions - searching the BBMRI-ERIC Directory for candidate hits to try to link with MDR records, and searching the ECRIN MDR for candidate hits to try to link with Directory collections. Thereafter, a systematic search through the BBMRI-ERIC Directory was performed.

Results: The investigation of linkages in both directions resulted in a limited but promising number of linkages. The results of the systematic search of the Directory identified linkage of 202 studies, spanning 284 collections.

Conclusions: The analysis with existing data sources indicated that links between the BBMRI-ERIC and ECRIN collections exist, but also that they would be difficult to continuously identify and maintain without a great deal of manual work which neither organisation could support. The question arises whether, in the future, systems could be put into place to make the exchange of information and the linkage of identifiers almost automatic.

背景:将临床研究和在临床研究中产生的(生物样本)集合联系起来有很大价值。然而,链接问题很难解决,因为临床研究和相关样本库之间通常没有直接的参考资料:方法:BBMRI-ERIC 目录和 ECRIN 元数据存储库(MDR)已经包含了链接临床研究和相关样本集所需的大部分信息。在本研究中,我们介绍了在这两个系统的现有相应记录中查找和实现这些链接的工作。MDR 研究与 BBMRI-ERIC 目录中相关样本库之间的链接过程首先是探索双向链接--在 BBMRI-ERIC 目录中搜索候选点击,尝试与 MDR 记录链接;在 ECRIN MDR 中搜索候选点击,尝试与目录样本库链接。随后,对 BBMRI-ERIC 目录进行了系统搜索:结果:对两个方向的链接进行调查后,发现了数量有限但很有希望的链接。对目录进行系统搜索的结果确定了 202 项研究的关联,涉及 284 个文集:对现有数据源的分析表明,BBMRI-ERIC 和 ECRIN 资料库之间存在着联系,但如果不进行大量的手工工作,就很难持续识别和维护这些联系,而这两个组织都无法提供支持。问题是,将来是否可以建立一些系统,使信息交流和标识符的连接几乎实现自动 化。
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引用次数: 0
On the Billefjorden fault zone in Garmdalen, central Spitsbergen: implications for the mapping of major fault zones during geological fieldwork and for the tectonic history of Svalbard. 斯匹次卑尔根中部加姆达伦的比勒菲尤登断层带:对在地质野外工作中绘制主要断层带的影响以及对斯瓦尔巴特构造史的影响。
Pub Date : 2024-10-02 eCollection Date: 2024-01-01 DOI: 10.12688/openreseurope.17826.2
Jean-Baptiste P Koehl, Eirik M B Stokmo, Jhon M Muñoz-Barrera

Background: The present contribution reexamines the geometry of a segment of a presumably long-lived fault in Svalbard, the Balliolbreen Fault segment of the Billefjorden Fault Zone, along which presumably two basement terranes of Svalbard accreted in the early-mid Paleozoic after thousands of kilometers strike-slip displacement.

Methods: We performed structural fieldwork to Billefjorden in central Spitsbergen and interpreted satellite images.

Results: Field observations demonstrate that the Balliolbreen Fault formed as a top-west thrust fault in the early Cenozoic and that weak sedimentary units such as shales of the Lower Devonian Wood Bay Formation and coals of the uppermost Devonian-Mississippian Billefjorden Group partitioned deformation, resulting in significant contrast in deformation intensity between stratigraphic units. For example, tight early Cenozoic folds are localized in shales of the Wood Bay Formation and contemporaneous top-west brittle-ductile thrusts within coals of the Billefjorden Group, whereas Pennsylvanian deposits of the Hultberget (and/or Ebbadalen?) Formation are simply folded into gentle open folds. Rheological contrasts also resulted in the development of décollements locally, e.g., between tightly folded strata of the Wood Bay Formation and Billefjorden Group and flat-lying, brecciated limestone-dominated strata of the Wordiekammen Formation. Despite the limited quality and continuity of outcrops in the area, the eastward-thickening character (i.e., away from the fault) of Pennsylvanian deposits of the Hultberget, Ebbadalen, and Minkinfjellet formations suggests that the fault did not act as a normal fault in Pennsylvanian times.

Conclusions: The study suggests that strain partitioning of early Cenozoic Eurekan contraction alone may explain the deformation patterns in Paleozoic rock units in central Spitsbergen, i.e., that Late Devonian Svalbardian contraction is not required, and that a major segment of the Billefjorden Fault Zone formed in the early Cenozoic. The present work illustrates the crucial need for interdisciplinary approaches and composite educational backgrounds in science.

背景:本论文重新研究了斯瓦尔巴群岛一条可能存在已久的断层--比勒菲尤登断层带的巴利奥尔布林断层段的几何形状,据推测,斯瓦尔巴群岛的两块基底陆相在古生代早中期经过数千公里的走向滑动位移后沿该断层段增生:我们在斯匹次卑尔根中部的比勒峡湾进行了结构实地考察,并对卫星图像进行了解读:野外观测结果表明,巴利奥尔布林断层在新生代早期形成了一个顶部向西的推力断层,泥盆纪下统伍德湾地层的页岩和泥盆纪-密西西比纪最上层比勒菲尤登组的煤炭等薄弱沉积单元对变形进行了分区,导致地层单元之间的变形强度反差很大。例如,伍德湾地层的页岩中存在新生代早期的紧密褶皱,比勒费尔登组煤炭中存在同时代的顶部-西部脆性-韧性推力,而 Hultberget(和/或 Ebbadalen?)地层的宾夕法尼亚沉积则只是简单地褶皱成平缓的开放褶皱。流变对比也导致了局部地区的褶皱发育,例如,在伍德湾地层和比勒费尔登组的紧密褶皱地层与沃迪卡门地层的平坦、以角砾岩为主的石灰岩地层之间。尽管该地区出露地层的质量和连续性有限,但 Hultberget、Ebbadalen 和 Minkinfjellet 地层的宾夕法尼亚沉积物向东增厚(即远离断层)的特征表明,该断层在宾夕法尼亚时期并非正常断层:这项研究表明,仅新生代早期尤里坎收缩的应变分区就可以解释斯匹次卑尔根中部古生代岩石单元的变形模式,即不需要晚泥盆世的斯瓦尔巴德收缩,比勒菲尤登断层带的主要部分形成于新生代早期。本研究成果表明,在科学领域,跨学科方法和复合教育背景至关重要。
{"title":"On the Billefjorden fault zone in Garmdalen, central Spitsbergen: implications for the mapping of major fault zones during geological fieldwork and for the tectonic history of Svalbard.","authors":"Jean-Baptiste P Koehl, Eirik M B Stokmo, Jhon M Muñoz-Barrera","doi":"10.12688/openreseurope.17826.2","DOIUrl":"https://doi.org/10.12688/openreseurope.17826.2","url":null,"abstract":"<p><strong>Background: </strong>The present contribution reexamines the geometry of a segment of a presumably long-lived fault in Svalbard, the Balliolbreen Fault segment of the Billefjorden Fault Zone, along which presumably two basement terranes of Svalbard accreted in the early-mid Paleozoic after thousands of kilometers strike-slip displacement.</p><p><strong>Methods: </strong>We performed structural fieldwork to Billefjorden in central Spitsbergen and interpreted satellite images.</p><p><strong>Results: </strong>Field observations demonstrate that the Balliolbreen Fault formed as a top-west thrust fault in the early Cenozoic and that weak sedimentary units such as shales of the Lower Devonian Wood Bay Formation and coals of the uppermost Devonian-Mississippian Billefjorden Group partitioned deformation, resulting in significant contrast in deformation intensity between stratigraphic units. For example, tight early Cenozoic folds are localized in shales of the Wood Bay Formation and contemporaneous top-west brittle-ductile thrusts within coals of the Billefjorden Group, whereas Pennsylvanian deposits of the Hultberget (and/or Ebbadalen?) Formation are simply folded into gentle open folds. Rheological contrasts also resulted in the development of décollements locally, e.g., between tightly folded strata of the Wood Bay Formation and Billefjorden Group and flat-lying, brecciated limestone-dominated strata of the Wordiekammen Formation. Despite the limited quality and continuity of outcrops in the area, the eastward-thickening character (i.e., away from the fault) of Pennsylvanian deposits of the Hultberget, Ebbadalen, and Minkinfjellet formations suggests that the fault did not act as a normal fault in Pennsylvanian times.</p><p><strong>Conclusions: </strong>The study suggests that strain partitioning of early Cenozoic Eurekan contraction alone may explain the deformation patterns in Paleozoic rock units in central Spitsbergen, i.e., that Late Devonian Svalbardian contraction is not required, and that a major segment of the Billefjorden Fault Zone formed in the early Cenozoic. The present work illustrates the crucial need for interdisciplinary approaches and composite educational backgrounds in science.</p>","PeriodicalId":74359,"journal":{"name":"Open research Europe","volume":"4 ","pages":"147"},"PeriodicalIF":0.0,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11541080/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Systematic review: locating qualitative academic publications for reviewing tenants' and landlords' renting experiences and interaction in the Majority World. 系统回顾:寻找定性学术出版物,回顾多数世界中房客和房东的租房经历和互动。
Pub Date : 2024-10-02 eCollection Date: 2024-01-01 DOI: 10.12688/openreseurope.18234.1
Adriana Mihaela Soaita

This methodological protocol describes the step-by-step process of identifying the relevant international academic literature to be reviewed within the project 'The affective economies of emerging private renting markets: understanding tenants and landlords in postcommunist Romania" (AFFECTIVE-PRS). It presents: (1) the preliminary decisions taken related to the breadth of the review (choice of databases, type of research, type of reference, searching fields); (2) the operationalisation of keywords and Boolean strings; (3) the further calibration of the searching parameters through piloting; (4) the final retrieval of relevant references through systematic and manual searches; and (5) the geographical coverage of the retained literature. While the paper demonstrates the rigour of the methodological approach taken, it also opens up the space for other scholars to scrutinise, replicate or adjust this approach to their own work.

本方法论规程介绍了在 "新兴私人租赁市场的情感经济:了解后共产主义罗马尼亚的租户和房东"(AFFECTIVE-PRS)项目中确定要审查的相关国际学术文献的逐步过程。报告介绍了(1) 与审查范围有关的初步决定(数据库选择、研究类型、参考文献类型、搜索字段);(2) 关键字和布尔字符串的操作;(3) 通过试点进一步校准搜索参数;(4) 通过系统和人工搜索最终检索相关参考文献;以及 (5) 保留文献的地理覆盖范围。本文在展示所采用方法的严谨性的同时,也为其他学者仔细研究、复制或调整自己的工作方法开辟了空间。
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引用次数: 0
Digital twins for managing bridge climate change adaptation. 管理桥梁适应气候变化的数字双胞胎。
Pub Date : 2024-09-26 eCollection Date: 2024-01-01 DOI: 10.12688/openreseurope.17809.2
Sakdirat Kaewunruen, Hao Fu, Adefolarin Adebiyi, Pasakorn Sengsri

Background: Bridges are vital construction infrastructures that almost every nation needs in order to function. Climate change is a significant issue, that especially affects the construction industry. It is very important that bridges are able to withstand the impacts of climate change and adaptation measures will be required to achieve this.

Methods: The digital twin will be developed using BIM to manage the climate change adaptation measures for the bridges. A 6D BIM model will be created that includes the 3D Revit model of a bridge featuring climate change measures, the climate change adaptation measures timeline schedule, climate change adaptation cost estimation, and carbon emission estimation, which will be produced using Revit software, Navisworks, and Granta EduPack. The results will show how 6D BIM can be used to support the adaptation of bridges to the effects of climate change.

Results: The findings underscore the efficacy of 6D BIM in enhancing bridge resilience against climate change impacts. The 3D model demonstrates integration of adaptation measures without compromising bridge functionality. Moreover, the 4D model's timeline scheduling facilitates hazard anticipation, project planning, communication enhancement, collaborative efforts, and project visualization. Cost estimations from the 5D model reveal varying costs among adaptation measures, while the 6D model highlights differences in carbon footprints. These BIM dimensions enable stakeholders to analyse effects on project costs and energy consumption, aiding sustainability and cost-efficiency considerations.

Conclusions: The study exhibits the literature review analysis, the risk assessment, research on climate change adaptation strategies, and implementation using Revit 2022, Navisworks 2022, and Granta EduPack software. By contributing to the adaptation of bridges to climate change effects, the research has provided valuable insights and practical implications for enhancing bridge resilience globally.

背景:桥梁是重要的建筑基础设施,几乎每个国家都需要桥梁才能正常运转。气候变化是一个重大问题,对建筑行业的影响尤为明显。桥梁能够抵御气候变化的影响非常重要,为此需要采取适应措施:将使用 BIM 开发数字孪生模型,以管理桥梁的气候变化适应措施。将使用 Revit 软件、Navisworks 和 Granta EduPack 创建一个 6D BIM 模型,其中包括以气候变化措施为特色的桥梁 3D Revit 模型、气候变化适应措施时间表、气候变化适应成本估算和碳排放估算。结果将显示如何利用 6D BIM 支持桥梁适应气候变化的影响:结果:研究结果强调了 6D BIM 在增强桥梁抵御气候变化影响方面的功效。三维模型展示了在不影响桥梁功能的情况下对适应措施的整合。此外,4D 模型的时间进度安排有助于灾害预测、项目规划、加强沟通、协同工作和项目可视化。5D 模型的成本估算显示了不同适应措施的成本差异,而 6D 模型则突出了碳足迹的差异。这些 BIM 维度使利益相关者能够分析对项目成本和能源消耗的影响,有助于考虑可持续性和成本效益:本研究展示了文献综述分析、风险评估、气候变化适应战略研究以及使用 Revit 2022、Navisworks 2022 和 Granta EduPack 软件的实施情况。这项研究有助于桥梁适应气候变化的影响,为提高全球桥梁的抗灾能力提供了宝贵的见解和实际意义。
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引用次数: 0
Disinformation as an obstructionist strategy in climate change mitigation: a review of the scientific literature for a systemic understanding of the phenomenon. 将虚假信息作为减缓气候变化的阻挠策略:回顾科学文献以系统了解这一现象。
Pub Date : 2024-09-24 eCollection Date: 2024-01-01 DOI: 10.12688/openreseurope.18180.2
Manuel Gertrudix, Alejandro Carbonell-Alcocer, Rubén Arcos, Cristina M Arribas, Valeri Codesido-Linares, Nerea Benítez-Aranda

Background: This study examines the scientific misinformation about climate change, in particular obstructionist strategies. The study aims to understand their impact on public perception and climate policy and emphasises the need for a systemic understanding that includes the financial, economic and political roots.

Methods: A systematic literature review (SLR) was conducted using the PRISMA 2020 model. The sample consisted of 75 articles published between 2019 and 2023, sourced from Web of Science, Scopus and Google Scholar. Methodological triangulation was performed to improve the analysis.

Results: The results show that technological approaches to misinformation detection, such as immunisation and fact-checking, are widely used. However, few studies look in depth at the operational structures that support systematic disinformation.

Conclusions: The study emphasises the urgent need to expand and deepen research on climate disinformation and argues for more global, comparative and adequately funded studies. It emphasises the importance of addressing the systemic complexity of disinformation and integrating different theoretical and methodological approaches. This will help to develop effective measures against hidden networks of influence and mitigate their disruptive effects. The research findings are relevant for policymakers, scientists, academics, the media and the public and will help to improve strategies to combat climate misinformation and promote science-based climate action.

背景:本研究探讨了有关气候变化的科学误导,尤其是阻挠战略。研究旨在了解其对公众认知和气候政策的影响,并强调需要系统地了解包括金融、经济和政治根源在内的各种因素:方法:采用 PRISMA 2020 模型进行了系统文献综述(SLR)。样本包括 2019 年至 2023 年间发表的 75 篇文章,来源于 Web of Science、Scopus 和 Google Scholar。为改进分析,还进行了方法三角测量:结果表明,错误信息检测的技术方法,如免疫和事实检查,得到了广泛应用。然而,很少有研究深入探讨支持系统性虚假信息的运作结构:本研究强调,迫切需要扩大和深化对气候虚假信息的研究,并主张开展更多全球性、比较性和资金充足的研究。它强调了解决虚假信息的系统复杂性以及整合不同理论和方法的重要性。这将有助于针对隐蔽的影响网络制定有效措施,并减轻其破坏性影响。这些研究成果对政策制定者、科学家、学者、媒体和公众都具有现实意义,将有助于改进打击气候误导的战略,促进以科学为基础的气候行动。
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引用次数: 0
ENOVAT: the European Network for Optimization of Veterinary Antimicrobial Treatment. ENOVAT:欧洲兽医抗菌治疗优化网络。
Pub Date : 2024-09-24 eCollection Date: 2024-01-01 DOI: 10.12688/openreseurope.18016.1
Peter Damborg, Fergus Allerton, Alain Bousquet-Mélou, Chantal Britt, Petra Cagnardi, Luis Pedro Carmo, Iskra Cvetkovikj, Marcel Erhard, Annet Heuvelink, Lisbeth Rem Jessen, Gudrun Overesch, Ludovic Pelligand, Jonathan Gómez Raja, Karolina Scahill, Dorina Timofte, Ana P Vale, Kees Veldman, Els M Broens

The global antimicrobial resistance crisis has been the driver of several international strategies on antimicrobial stewardship. For their implementation at the field level, the veterinary sector encounters several specific challenges and in particular: (i) a shortage of experts in key disciplines related to antimicrobial stewardship, (ii) a lack of evidence-based antimicrobial treatment guidelines, and (iii) inferior diagnostic tests available compared to human medicine. The present white paper describes how the COST Action ENOVAT (the European Network for Optimization of Veterinary Antimicrobial Treatment, CA18217), comprising 332 persons from 51 countries, worked towards solutions to these challenges. Initially, surveys were conducted to explore the present state in Europe in terms of existing antimicrobial use guidelines and microbiology practices performed. Concurrently, various research activities were launched to optimize diagnostics, including development of epidemiological cut-offs, clinical breakpoints and matrix-assisted laser desorption ionization time of flight mass spectrometry interpretive criteria. Also, guidelines drafting groups working towards evidence-based antimicrobial treatment guidelines for six conditions in food-producing and companion animals were established. The processes and outcomes, also in terms of capacity building, are summarized in this white paper where emphasis is placed on sustainability of the activities. Although several ENOVAT initiatives and spin-off projects will continue beyond the Action, we recommend that a new European veterinary research agenda is launched focusing on research and funding leading to long-term impacts on veterinary antimicrobial use.

全球抗菌药耐药性危机推动了多项抗菌药管理国际战略的实施。在实地实施这些战略时,兽医部门遇到了一些具体挑战,尤其是:(i) 缺乏与抗菌药物管理相关的关键学科专家,(ii) 缺乏循证抗菌药物治疗指南,(iii) 与人类医学相比,现有的诊断测试较差。本白皮书介绍了由来自 51 个国家的 332 人组成的 COST 行动 ENOVAT(欧洲兽医抗菌药物治疗优化网络,CA18217)如何致力于解决这些挑战。首先,对欧洲现有的抗菌剂使用指南和微生物学实践进行了调查,以了解其现状。与此同时,还开展了各种研究活动,以优化诊断方法,包括制定流行病学截断点、临床断点和基质辅助激光解吸电离飞行时间质谱解释标准。此外,还成立了准则起草小组,为食品生产动物和伴侣动物的六种疾病制定循证抗菌治疗准则。本白皮书概述了能力建设方面的进程和成果,并强调了活动的可持续性。尽管 ENOVAT 的一些倡议和附带项目在行动结束后仍将继续,但我们建议启动新的欧洲兽医研究议程,重点关注对兽医抗菌药物使用产生长期影响的研究和资助。
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引用次数: 0
An in-depth analysis of data reduction methods for sustainable deep learning. 深入分析可持续深度学习的数据缩减方法。
Pub Date : 2024-09-18 eCollection Date: 2024-01-01 DOI: 10.12688/openreseurope.17554.2
Javier Perera-Lago, Victor Toscano-Duran, Eduardo Paluzo-Hidalgo, Rocio Gonzalez-Diaz, Miguel A Gutiérrez-Naranjo, Matteo Rucco

In recent years, deep learning has gained popularity for its ability to solve complex classification tasks. It provides increasingly better results thanks to the development of more accurate models, the availability of huge volumes of data and the improved computational capabilities of modern computers. However, these improvements in performance also bring efficiency problems, related to the storage of datasets and models, and to the waste of energy and time involved in both the training and inference processes. In this context, data reduction can help reduce energy consumption when training a deep learning model. In this paper, we present up to eight different methods to reduce the size of a tabular training dataset, and we develop a Python package to apply them. We also introduce a representativeness metric based on topology to measure the similarity between the reduced datasets and the full training dataset. Additionally, we develop a methodology to apply these data reduction methods to image datasets for object detection tasks. Finally, we experimentally compare how these data reduction methods affect the representativeness of the reduced dataset, the energy consumption and the predictive performance of the model.

近年来,深度学习因其解决复杂分类任务的能力而广受欢迎。得益于更精确模型的开发、海量数据的可用性以及现代计算机计算能力的提高,深度学习能提供越来越好的结果。然而,性能的提高也带来了效率问题,这与数据集和模型的存储有关,也与训练和推理过程中的能源和时间浪费有关。在这种情况下,减少数据有助于降低深度学习模型训练时的能耗。在本文中,我们介绍了多达八种不同的方法来减小表格式训练数据集的大小,并开发了一个 Python 软件包来应用这些方法。我们还引入了一种基于拓扑结构的代表性指标,用于衡量缩小后的数据集与完整训练数据集之间的相似性。此外,我们还开发了一种方法,将这些数据缩减方法应用于图像数据集,以完成物体检测任务。最后,我们通过实验比较了这些数据缩减方法如何影响缩减后数据集的代表性、能耗和模型的预测性能。
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引用次数: 0
Collaborative Policymaking: a qualitative systematic review of advice for policymakers. 合作决策:对决策者建议的定性系统审查。
Pub Date : 2024-09-18 eCollection Date: 2024-01-01 DOI: 10.12688/openreseurope.18440.1
Paul Cairney, Claire Toomey

Background: Complex policy problems are not amenable to simple solutions by a few powerful policy actors in one central government. They require collaboration across government and between actors inside and outside of government. However, this requirement for collaboration is no guarantee of collective action. Further, it is difficult to know how to collaborate effectively. We searched the academic and grey literature for advice on how to foster collaborative policymaking.

Methods: We conducted a qualitative systematic review (2024) of peer reviewed journal articles (Web of Science) and grey literature reports (Policy Commons). Each article or report had to inform advice on collaborative policymaking. We used an immersive and inductive approach to identify key themes and relate the results to well-established insights from policy theories.

Results: 86 texts meet the inclusion criteria (49 Web of Science, 37 Policy Commons). Most provide broad definitions of collaborative policymaking, which are similar to definitions of collaborative governance (and connected aims such as policy co-creation). Many assert or assume that greater collaboration, across and inside/outside of government, will improve policymaking and policy. Few individual studies give advice on how to collaborate effectively, but they combine to identify common features of collaboration.

Conclusions: We synthesise the available advice to identify five main features of collaborative policymaking: plan and prepare to collaborate, such as by designing rules and allocating resources; create a sense of collective purpose, such as by setting a boundary around the collaboration and co-producing a common vision; foster creative methods to visualise collaboration and design policy; create new forums to supplement formal collaboration; and clarify the roles and skills essential to each collaborative task.

背景:复杂的政策问题不是一个中央政府中少数强有力的政策参与者所能简单解决的。它们需要政府各部门之间以及政府内外各部门之间的协作。然而,这种合作要求并不能保证集体行动。此外,我们也很难知道如何进行有效合作。我们搜索了学术文献和灰色文献,以寻求有关如何促进合作决策的建议:我们对同行评审的期刊文章(Web of Science)和灰色文献报告(Policy Commons)进行了定性系统审查(2024)。每篇文章或报告都必须为合作决策提供建议。我们采用沉浸式和归纳式方法来确定关键主题,并将结果与政策理论的成熟见解联系起来:86 篇文章符合纳入标准(49 篇 Web of Science,37 篇 Policy Commons)。大多数文章提供了协作决策的广泛定义,这些定义与协作治理(以及政策共创等相关目标)的定义相似。许多研究断言或假定,加强政府内部/外部的合作将改善决策和政策。很少有单项研究就如何有效合作提出建议,但这些研究共同确定了合作的共同特征:我们综合了现有的建议,确定了合作决策的五个主要特征:规划并准备合作,如设计规则和分配资源;创造集体目的感,如设定合作边界和共同制定共同愿景;促进创造性方法,以可视化合作和设计政策;创建新论坛,以补充正式合作;明确每项合作任务所必需的角色和技能。
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引用次数: 0
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Open research Europe
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