Pub Date : 2024-07-21DOI: 10.21608/asmj.2024.291595.1276
Basma M. Eissa, Eman H. Elsebaei, Amany A. Salem, Hadeer Abd al-azim, Noha A. Abdelmoneim, Sara A. Blamoun, Dina O. Abdulazim
{"title":"Fibromyalgia and Depression in Egyptian Medical Students: A Cross-sectional Study of Impact on Physical Functional Status","authors":"Basma M. Eissa, Eman H. Elsebaei, Amany A. Salem, Hadeer Abd al-azim, Noha A. Abdelmoneim, Sara A. Blamoun, Dina O. Abdulazim","doi":"10.21608/asmj.2024.291595.1276","DOIUrl":"https://doi.org/10.21608/asmj.2024.291595.1276","url":null,"abstract":"","PeriodicalId":7450,"journal":{"name":"Ain Shams Medical Journal","volume":"40 26","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141818124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-21DOI: 10.21608/asmj.2024.292211.1277
moustafa bakrey hamed ata, Z. Kasemy, Mohamed Fahmy Amara, Ahmed Mohammed Zahran, S. Zewain
{"title":"Prevalence and Factors Associated with Medication non-adherence among diabetic patients Attending at Menoufia University Hospitals","authors":"moustafa bakrey hamed ata, Z. Kasemy, Mohamed Fahmy Amara, Ahmed Mohammed Zahran, S. Zewain","doi":"10.21608/asmj.2024.292211.1277","DOIUrl":"https://doi.org/10.21608/asmj.2024.292211.1277","url":null,"abstract":"","PeriodicalId":7450,"journal":{"name":"Ain Shams Medical Journal","volume":"99 43","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141818574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-21DOI: 10.21608/asmj.2024.267292.1216
Safa Masser Kamosh, Huda Noor Hasan, Afrah A. Habeeb, Malath I. Yousif, Masar J al kurdy, Roaa Abed Jaythoom
{"title":"Polycystic ovary syndrome (PCOS) – A Review","authors":"Safa Masser Kamosh, Huda Noor Hasan, Afrah A. Habeeb, Malath I. Yousif, Masar J al kurdy, Roaa Abed Jaythoom","doi":"10.21608/asmj.2024.267292.1216","DOIUrl":"https://doi.org/10.21608/asmj.2024.267292.1216","url":null,"abstract":"","PeriodicalId":7450,"journal":{"name":"Ain Shams Medical Journal","volume":"26 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141818283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-21DOI: 10.21608/asmj.2024.290779.1275
Dalia Diaa ElDine Salem, Amal Mohamed, H. Hebah, A. Abdelghany
{"title":"Serum Erythroferrone, a Biomarker of Erythropoietic Activity in End-Stage Renal Disease Patients","authors":"Dalia Diaa ElDine Salem, Amal Mohamed, H. Hebah, A. Abdelghany","doi":"10.21608/asmj.2024.290779.1275","DOIUrl":"https://doi.org/10.21608/asmj.2024.290779.1275","url":null,"abstract":"","PeriodicalId":7450,"journal":{"name":"Ain Shams Medical Journal","volume":"64 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141817723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-21DOI: 10.21608/asmj.2024.292503.1278
Basma M. Eissa, Arwa Al-Shaarawy, Eman H. Elsebaei, Amany A. Salem, Ashrakat M. Deyab, Ahmad Ibrahim, Dina O. Abdulazim
{"title":"Proportion and Determinants of Fibromyalgia in a Sample of Egyptians with Higher Education (Physicians and Non-physicians): A Comparative Cross-sectional Study.","authors":"Basma M. Eissa, Arwa Al-Shaarawy, Eman H. Elsebaei, Amany A. Salem, Ashrakat M. Deyab, Ahmad Ibrahim, Dina O. Abdulazim","doi":"10.21608/asmj.2024.292503.1278","DOIUrl":"https://doi.org/10.21608/asmj.2024.292503.1278","url":null,"abstract":"","PeriodicalId":7450,"journal":{"name":"Ain Shams Medical Journal","volume":"87 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141818733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-01DOI: 10.21608/asmj.2023.321916
Rania Elsyade, Heba Abd Elfatah, Noha Shawky, Eman El-Sawaf
: Background: Glucocorticoid is the most common cause of medication-induced osteoporosis. Aim of the work: Comparing the role of Nigella sativa ( NS) versus calcium and vitamin D (Ca+Vit D) in the protection from Glucocorticoid-induced osteoporosis in a rat model. Material and Methods: Fifty-one male albino rats weighing 120-150 gm were divided into 4 groups: Group I (Control), Group II (dexamethasone group), Group III (dexamethasone plus Ca+Vit D), and Group IV (dexamethasone plus NS oil). Results: Rats of group II revealed erosion cavities in compact bone with eroded surface and widened Haversian canal and osteocyte lacunae. The cancellous bone showed thin disconnected bone trabeculae containing empty lacunae with wide bone marrow spaces. Areas of faintly stained bone matrix and minor fractures could be detected. These results were confirmed by a significant decrease in the thickness and number of lacunae containing osteocytes in cortical and cancellous bone. Also, there was an apparent decrease in osteopontin and an increase in caspase-3immune reaction. Moreover, a significant increase in alkaline phosphatase and IL6 was detected. Groups III and IV showed improvement in cortical and trabecular bone structure. The expression of osteopontin, caspase-3, alkaline phosphatase, and IL6 was also improved. Conclusion: This study demonstrated that supplementation of NS oil was better than calcium and vitamin D in osteoporotic lesions of rat femur due to its effect on bone remodeling. It acts as a calcium source and has antioxidant effects. So, it is recommended to use NS in the protection of glucocorticoid-induced osteoporosis.
{"title":"THE PUTATIVE ROLE OF NIGELLA SATIVA OIL VERSUS CALCIUM AND VITAMIN D IN MODULATING THE GLUCOCORTICOID-INDUCED OSTEOPOROSIS IN RATS: HISTOLOGICAL AND IMMUNOHISTOCHEMICAL STUDY.","authors":"Rania Elsyade, Heba Abd Elfatah, Noha Shawky, Eman El-Sawaf","doi":"10.21608/asmj.2023.321916","DOIUrl":"https://doi.org/10.21608/asmj.2023.321916","url":null,"abstract":": Background: Glucocorticoid is the most common cause of medication-induced osteoporosis. Aim of the work: Comparing the role of Nigella sativa ( NS) versus calcium and vitamin D (Ca+Vit D) in the protection from Glucocorticoid-induced osteoporosis in a rat model. Material and Methods: Fifty-one male albino rats weighing 120-150 gm were divided into 4 groups: Group I (Control), Group II (dexamethasone group), Group III (dexamethasone plus Ca+Vit D), and Group IV (dexamethasone plus NS oil). Results: Rats of group II revealed erosion cavities in compact bone with eroded surface and widened Haversian canal and osteocyte lacunae. The cancellous bone showed thin disconnected bone trabeculae containing empty lacunae with wide bone marrow spaces. Areas of faintly stained bone matrix and minor fractures could be detected. These results were confirmed by a significant decrease in the thickness and number of lacunae containing osteocytes in cortical and cancellous bone. Also, there was an apparent decrease in osteopontin and an increase in caspase-3immune reaction. Moreover, a significant increase in alkaline phosphatase and IL6 was detected. Groups III and IV showed improvement in cortical and trabecular bone structure. The expression of osteopontin, caspase-3, alkaline phosphatase, and IL6 was also improved. Conclusion: This study demonstrated that supplementation of NS oil was better than calcium and vitamin D in osteoporotic lesions of rat femur due to its effect on bone remodeling. It acts as a calcium source and has antioxidant effects. So, it is recommended to use NS in the protection of glucocorticoid-induced osteoporosis.","PeriodicalId":7450,"journal":{"name":"Ain Shams Medical Journal","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135736851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
: Background: Complex intracranial aneurysms (CIAs) are technically challenging neurosurgical pathologies, and despite extensive efforts to treat these intricate vascular lesions, no formal management guidelines exist in the literature. In this study, we evaluate contemporary clinical practice and recent trends and outcomes in managing anterior circulation CIAs. Methods: This study is a prospective observational study that included 40 patients. All patients were evaluated by multidisciplinary team (MDT) consisting of neuro-endovascular radiologists, vascular neurosurgeons, and neurologists for assessment of the therapeutic options. Results: Twenty cases were managed surgically, while 18 were treated by various endovascular techniques. Surgical and endovascular modalities were used as a hybrid approach to treat 2 cases. Recurrence or residual of treated aneurysms was seen only in the endovascular cohort (Four cases out of the 18 cases treated by endovascular techniques). Four documented intervention related mortalities occurred during the first 6 months. Conclusion: CIAs managed surgically showed less recurrence rate than those treated by different endovascular techniques. CIAs treated by endovascular modalities showed much lower length of hospital stay and better modified Rankin scale after 6 months. Complications rate and mortality rate were similar in both groups and were usually related to the initial poor presentation with high World Federation of Neurosurgical Societies (WFNS) grades upon the initial ictus.
{"title":"TREATMENT MODALITIES & OUTCOME TRENDS OF COMPLEX ANTERIOR CIRCULATION INTRACRANIAL ANEURYSMS: A CASE SERIES STUDY","authors":"Eslam Hussein, Christos Tolias, Micheal Lawton, Osama Aglan, Mohamed Habib, Hussein Moharram, Mohamed Aziz","doi":"10.21608/asmj.2023.321808","DOIUrl":"https://doi.org/10.21608/asmj.2023.321808","url":null,"abstract":": Background: Complex intracranial aneurysms (CIAs) are technically challenging neurosurgical pathologies, and despite extensive efforts to treat these intricate vascular lesions, no formal management guidelines exist in the literature. In this study, we evaluate contemporary clinical practice and recent trends and outcomes in managing anterior circulation CIAs. Methods: This study is a prospective observational study that included 40 patients. All patients were evaluated by multidisciplinary team (MDT) consisting of neuro-endovascular radiologists, vascular neurosurgeons, and neurologists for assessment of the therapeutic options. Results: Twenty cases were managed surgically, while 18 were treated by various endovascular techniques. Surgical and endovascular modalities were used as a hybrid approach to treat 2 cases. Recurrence or residual of treated aneurysms was seen only in the endovascular cohort (Four cases out of the 18 cases treated by endovascular techniques). Four documented intervention related mortalities occurred during the first 6 months. Conclusion: CIAs managed surgically showed less recurrence rate than those treated by different endovascular techniques. CIAs treated by endovascular modalities showed much lower length of hospital stay and better modified Rankin scale after 6 months. Complications rate and mortality rate were similar in both groups and were usually related to the initial poor presentation with high World Federation of Neurosurgical Societies (WFNS) grades upon the initial ictus.","PeriodicalId":7450,"journal":{"name":"Ain Shams Medical Journal","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135736853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-01DOI: 10.21608/asmj.2023.321828
Sarah Roshdy, Ahmed Monib, Asmaa Salama, Sherihan Madkour
: Background: Adnexal masses are common incidental finding during imaging, which cause diagnostic dilemma. Appropriate preoperative evaluation to discriminate between benign and malignant adnexal masses helps to decide the best management and improves survival rate. The most accurate diagnostic method is the contrast MRI to differentiate benign from malignant adnexal masses. Contrast MRI is contraindicated in patients with chronic kidney diseases as well as it may cause allergic reactions. In addition, contrast studies need more time and are expensive. So, Non-contrast MRI may be a diagnostic alternative method when the administration of intravenous contrast medium is not possible. Aim of the Work: Detection of the sensitivity and specificity of abbreviated non-contrast MRI compared with contrast MRI study in evaluation of adnexal masses by using non-contrast and O-RADS scoring systems with detection of inter-reader agreement. Patient and Methods: This study included 30 patients had adnexal masses with age ranging from 18 to 78 years, referred to MRI unit in Ain Shams University Hospitals from February 2022 to January 2023. Comparison between Non-Contrast MRI and ORADs scoring system was done to interpret sensitivity and specificity of non-contrast MRI study. Comparison between readers was done to interpret inter-reader agreement Results: Non-Contrast MRI study compared with Contrast MRI study showed high specificity (92.3%), high sensitivity (100%) and high accuracy (95%). There was no statistically significant difference found between contrast & non-contrast MRI with high inter-reader agreement. Conclusion: Non-contrast MRI has high accuracy and high inter-reader agreement for characterization of adnexal masses. So, Non-Contrast MRI can be a safe alternative method when contrast use is contraindicated.
{"title":"EFFICACY OF NON-CONTRAST MRI STUDIES IN CHARACTERIZATION OF ADNEXAL MASSES COMPARED TO CONTRAST STUDIES","authors":"Sarah Roshdy, Ahmed Monib, Asmaa Salama, Sherihan Madkour","doi":"10.21608/asmj.2023.321828","DOIUrl":"https://doi.org/10.21608/asmj.2023.321828","url":null,"abstract":": Background: Adnexal masses are common incidental finding during imaging, which cause diagnostic dilemma. Appropriate preoperative evaluation to discriminate between benign and malignant adnexal masses helps to decide the best management and improves survival rate. The most accurate diagnostic method is the contrast MRI to differentiate benign from malignant adnexal masses. Contrast MRI is contraindicated in patients with chronic kidney diseases as well as it may cause allergic reactions. In addition, contrast studies need more time and are expensive. So, Non-contrast MRI may be a diagnostic alternative method when the administration of intravenous contrast medium is not possible. Aim of the Work: Detection of the sensitivity and specificity of abbreviated non-contrast MRI compared with contrast MRI study in evaluation of adnexal masses by using non-contrast and O-RADS scoring systems with detection of inter-reader agreement. Patient and Methods: This study included 30 patients had adnexal masses with age ranging from 18 to 78 years, referred to MRI unit in Ain Shams University Hospitals from February 2022 to January 2023. Comparison between Non-Contrast MRI and ORADs scoring system was done to interpret sensitivity and specificity of non-contrast MRI study. Comparison between readers was done to interpret inter-reader agreement Results: Non-Contrast MRI study compared with Contrast MRI study showed high specificity (92.3%), high sensitivity (100%) and high accuracy (95%). There was no statistically significant difference found between contrast & non-contrast MRI with high inter-reader agreement. Conclusion: Non-contrast MRI has high accuracy and high inter-reader agreement for characterization of adnexal masses. So, Non-Contrast MRI can be a safe alternative method when contrast use is contraindicated.","PeriodicalId":7450,"journal":{"name":"Ain Shams Medical Journal","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135736854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-01DOI: 10.21608/asmj.2023.321827
Mohamed Abdel Aziz, Mohamed Yosry, Ahmed Elshimy
: Background : The COVID-19 pandemic causes primarily respiratory disease as well as non-respiratory complications such as thromboembolic complications with D-dimer elevation, which lead to multisystem organ dysfunction and respiratory failure. Aim of the work : To determine the value of radiological assessment of vascular complications in COVID-19 infections and its relation to D-dimer levels as important tools for early diagnosis and proper management of these patients. Patients & Methods: The study included 100 patients diagnosed as COVID-19 positive with embolic manifestations depending on their symptoms, signs, and laboratory assessment, which included D-dimer levels. They underwent radiological assessment of their vascular complications, including CT, MRI, and CT angiography. Results: Among 100 COVID-positive patients with thromboembolic symptoms, 55 had evidence of pulmonary embolism, 13 had strokes, 4 had mesenteric arterial occlusion and 28 patients had no radiological evidence of vascular manifestations. D-dimer levels were increased (0.50 mcg/mL or greater) in 70 percent of positive COVID patients, including 89% of those with pulmonary embolism, 84% of those with stroke, 75% of mesenteric thrombosis cases, and in 7 patients (25% of those with symptoms suggestive of vascular thrombosis without radiological imaging of thromboembolic manifestations), with a sensitivity of 88.6%, specificity of 75%, positive predictive value of 90.9%, and negative predictive value of 70%. Conclusion: This study confirmed that D-dimer elevation in COVID-positive patients is highly suggestive of thromboembolic complications, especially pulmonary, cranial, and abdominal embolisms, and that confirmation by proper radiological evaluation is mandatory for the diagnosis of these findings and proper management of their complications.
{"title":"RADIOLOGICAL ASSESSMENT OF THE VASCULAR COMPLICATIONS OF COVID-19 IN CORRELATION WITH D-DIMER LEVEL","authors":"Mohamed Abdel Aziz, Mohamed Yosry, Ahmed Elshimy","doi":"10.21608/asmj.2023.321827","DOIUrl":"https://doi.org/10.21608/asmj.2023.321827","url":null,"abstract":": Background : The COVID-19 pandemic causes primarily respiratory disease as well as non-respiratory complications such as thromboembolic complications with D-dimer elevation, which lead to multisystem organ dysfunction and respiratory failure. Aim of the work : To determine the value of radiological assessment of vascular complications in COVID-19 infections and its relation to D-dimer levels as important tools for early diagnosis and proper management of these patients. Patients & Methods: The study included 100 patients diagnosed as COVID-19 positive with embolic manifestations depending on their symptoms, signs, and laboratory assessment, which included D-dimer levels. They underwent radiological assessment of their vascular complications, including CT, MRI, and CT angiography. Results: Among 100 COVID-positive patients with thromboembolic symptoms, 55 had evidence of pulmonary embolism, 13 had strokes, 4 had mesenteric arterial occlusion and 28 patients had no radiological evidence of vascular manifestations. D-dimer levels were increased (0.50 mcg/mL or greater) in 70 percent of positive COVID patients, including 89% of those with pulmonary embolism, 84% of those with stroke, 75% of mesenteric thrombosis cases, and in 7 patients (25% of those with symptoms suggestive of vascular thrombosis without radiological imaging of thromboembolic manifestations), with a sensitivity of 88.6%, specificity of 75%, positive predictive value of 90.9%, and negative predictive value of 70%. Conclusion: This study confirmed that D-dimer elevation in COVID-positive patients is highly suggestive of thromboembolic complications, especially pulmonary, cranial, and abdominal embolisms, and that confirmation by proper radiological evaluation is mandatory for the diagnosis of these findings and proper management of their complications.","PeriodicalId":7450,"journal":{"name":"Ain Shams Medical Journal","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135737566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-01DOI: 10.21608/asmj.2023.321910
Sara Tawfeek, Adel Nassar, Tayseer Abdel Rahman, Ghada Khalil
: Background: Cochlear implantation referred to as the treatment of choice for hearing rehabilitation in patients with bilateral severe to profound sensorineural hearing loss that is no longer responsive to amplification by hearing aids. The integrity of this CI can be assessed intraoperatively and postoperatively through objective measures which include telemetric measurement of electrode impedance and electrically evoked compound action potential. Aim of the work: To compare electrode impedance values and electrically evoked compound action potential (ECAP) thresholds intraoperatively and postoperatively to asses whether significant changes take place overtime or not. Patient and Methods This study was carried on 25 subjects with age ranging from (3-60) yrs. 21 of the subjects were implanted unilaterally with a MED-EL devices and 4 implanted with cochlear devices. Impedance values and ECAP thresholds were monitored at the time of surgery then postoperatively at 1 st day tunning, 1 month, 2 months and 6 th months after 1 st day tunning. Results: Intraoperative impedance value was the lowest among all readings measured in all electrodes. The highest value was that measured at the 1 st day tunning after surgery, after which impedance value continued to decrease significantly when compared to the 1 st day tunning. ECAP thresholds showed the highest value intraoperatively after which the ECAP continued to decrease. However, the difference between readings was statistically nonsignificant. Conclusion: During surgery, telemetry provides valuable information regarding integrity of electrodes, the electrical output of the implant and the response of the auditory system to electrical stimulation; however, it is not a valuable predictor of post-operative performance.
{"title":"IMPEDANCE AND ELECTRICALLY EVOKED COMPOUND ACTION POTENTIAL (ECAP) CHANGES OVERTIME IN PATIENTS WITH COCHLEAR IMPLANTS","authors":"Sara Tawfeek, Adel Nassar, Tayseer Abdel Rahman, Ghada Khalil","doi":"10.21608/asmj.2023.321910","DOIUrl":"https://doi.org/10.21608/asmj.2023.321910","url":null,"abstract":": Background: Cochlear implantation referred to as the treatment of choice for hearing rehabilitation in patients with bilateral severe to profound sensorineural hearing loss that is no longer responsive to amplification by hearing aids. The integrity of this CI can be assessed intraoperatively and postoperatively through objective measures which include telemetric measurement of electrode impedance and electrically evoked compound action potential. Aim of the work: To compare electrode impedance values and electrically evoked compound action potential (ECAP) thresholds intraoperatively and postoperatively to asses whether significant changes take place overtime or not. Patient and Methods This study was carried on 25 subjects with age ranging from (3-60) yrs. 21 of the subjects were implanted unilaterally with a MED-EL devices and 4 implanted with cochlear devices. Impedance values and ECAP thresholds were monitored at the time of surgery then postoperatively at 1 st day tunning, 1 month, 2 months and 6 th months after 1 st day tunning. Results: Intraoperative impedance value was the lowest among all readings measured in all electrodes. The highest value was that measured at the 1 st day tunning after surgery, after which impedance value continued to decrease significantly when compared to the 1 st day tunning. ECAP thresholds showed the highest value intraoperatively after which the ECAP continued to decrease. However, the difference between readings was statistically nonsignificant. Conclusion: During surgery, telemetry provides valuable information regarding integrity of electrodes, the electrical output of the implant and the response of the auditory system to electrical stimulation; however, it is not a valuable predictor of post-operative performance.","PeriodicalId":7450,"journal":{"name":"Ain Shams Medical Journal","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135737598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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