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Emollient therapy in children with atopic dermatitis – a pilot study 儿童特应性皮炎的润肤疗法-一项初步研究
IF 0.2 Pub Date : 2020-01-01 DOI: 10.5114/PJA.2020.96131
A. Jaworek, M. Jaworek, Przemysław Hałubiec, R. Kurzawa, A. Wojas-Pelc
Introduction: Atopic dermatitis is chronic and recurrent inflammatory dermatosis characterized by the pres-ence of skin pruritus and dryness. The crucial factor determining the therapeutic success is adequate collabo-ration between patient and physician. Emollients are recommended medications to be applicated at any point of atopic dermatitis management. Aim: To assess the impact of preferences, beliefs and adherence of caregivers of children suffering from atopic dermatitis in the aspect of recommended emollient therapy and their relationship to the symptoms severity in children. Material and methods: This is a pilot study. The answers from anonymous questionnaires regarding preferences, beliefs and adherence in the aspect of emollient therapy were collected from 50 parents of children suffering from atopic dermatitis. Each caregiver self-evaluated the itch severity using a visual-analogue scale as well as the skin condition in child. Nominal variables were compared using the c 2 test or 2-sided Fischer test. For the comparison between groups the Mann-Whitney’s U test and the Kruskal-Wallis’ test were used. Results: The predominantly selected formulation of emollient was the bath liquid/emulsion. A number of 39 caregivers remarked the positive effect of the emollient on the condition of skin in a child. The highest ratio of respondents applicated emollients twice a day. The determining factor for the choose of the emollient was the severity of skin lesions. Caregivers who indicated improvement in assessed skin condition and itch in children more frequently preferred emollients in the formulation of cream and ointment. According to the opinion of most study participants the crucial element of emollient therapy was the regular use of emollients. Regular use of emollients was an important factor related to the improvement of the clinical condition. Conclusions: Preferences and beliefs of caregivers may possess a significant impact on adherence during emollient therapy for atopic dermatitis in children which affects the benefits from treatment. The partnership of a physician and caregiver of a child with atopic dermatitis is the foundation for developing an individualized therapy schedule.
简介:特应性皮炎是一种慢性和复发性炎症性皮肤病,其特征是皮肤瘙痒和干燥。决定治疗成功的关键因素是医患之间的充分合作。润肤剂是推荐的药物,适用于任何点的特应性皮炎管理。目的:评估儿童特应性皮炎护理人员在推荐润肤治疗方面的偏好、信念和依从性的影响及其与儿童症状严重程度的关系。材料和方法:这是一项初步研究。对50名特应性皮炎患儿家长进行匿名问卷调查,问卷内容包括对润肤剂治疗的偏好、信念和依从性。每个护理人员使用视觉模拟量表自我评估瘙痒严重程度以及儿童的皮肤状况。名义变量的比较采用c2检验或双侧Fischer检验。组间比较采用Mann-Whitney’s U检验和Kruskal-Wallis检验。结果:润肤剂的主要选择配方为沐浴液/乳剂。39名护理人员评论了润肤剂对儿童皮肤状况的积极影响。受访者中使用润肤剂的比例最高,一天两次。选择润肤剂的决定因素是皮肤损伤的严重程度。指出改善评估的皮肤状况和儿童瘙痒的护理人员更经常选择软膏和软膏配方中的润肤剂。根据大多数研究参与者的意见,润肤疗法的关键因素是定期使用润肤剂。经常使用润肤剂是改善临床状况的重要因素。结论:护理人员的偏好和信念可能对儿童特应性皮炎润肤治疗期间的依从性有显著影响,从而影响治疗的效果。医生和儿童特应性皮炎护理人员的合作伙伴关系是制定个性化治疗计划的基础。
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引用次数: 0
Biological therapy of asthma – position statement of Polish Allergology Society (PTA) and Polish Society of Lung Diseases (PTChP) 哮喘的生物治疗——波兰过敏症学会(PTA)和波兰肺病学会(PTChP)立场声明
IF 0.2 Pub Date : 2020-01-01 DOI: 10.5114/pja.2020.96664
B. Rogala, M. Kupczyk, G. Bochenek, P. Śliwiński, M. Moniuszko, J. Glück, R. Dobek, M. Kulus
Biological therapy is the breakthrough in the management of spectrum of various diseases It also concerns asthma therapy The data regarding the role of biologics in the treatment strategy of severe asthma are presented The overview on how mediators of type 2 inflammation drives the pathology of the disease is given It justifies the biological treatment options approved The development of treatment strategy targeting non-type 2 inflammation is also highlighted The data regarding the risk and safety of biologics are discussed Document includes the featured rules of the classification of patients with severe asthma to this reliable and efficient therapy The outlook how to perceive the safety of biologics in the time of COVID-19 epidemic is also given
生物治疗是各种疾病谱系管理的突破,也涉及哮喘治疗,介绍了关于生物制剂在严重哮喘治疗策略中的作用的数据,概述了2型炎症介质如何驱动疾病的病理,给出了批准的生物治疗方案的理由,也强调了针对非2型炎症的治疗策略的发展,以及关于风险和风险的数据讨论了生物制剂的安全性,包括重症哮喘患者对这种可靠有效的治疗方法的分类特点,并对如何在COVID-19流行时期认识生物制剂的安全性提出了展望
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引用次数: 1
Vaccine against COVID-19 or against SARS-CoV-2 infection? 预防COVID-19或SARS-CoV-2感染的疫苗?
IF 0.2 Pub Date : 2020-01-01 DOI: 10.5114/pja.2020.97913
P. Rieske
Article offers analysis of main aspects of SARS-CoV-2/COVID-19 vaccination (severe acute respiratory syndrome coronavirus 2/COVID-19-Coronavirus Disease 2019) Optimal vaccine should protect not only against disease COVID-19 (symptoms), but also against SARS-CoV-2 infection (spreading disease) However, this kind of vaccine – showing highest safety level is extremely difficult to get Several additional SARS-CoV-2/COVID-19 vaccination issues were addressed in article For example: serological passports, herd immunity, clinical trials, and role of antibodies and T cells crossreactivities Article discusses some issues related to vaccination responsibilities
文章分析了SARS-CoV-2/COVID-19疫苗接种(严重急性呼吸综合征冠状病毒2/COVID-19冠状病毒病2019)的主要方面。最佳疫苗不仅应预防COVID-19疾病(症状),还应预防SARS-CoV-2感染(传播疾病)。然而,这种显示最高安全水平的疫苗极其难以获得。血清学护照、群体免疫、临床试验以及抗体和T细胞交叉反应的作用本文讨论了与疫苗接种责任有关的一些问题
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引用次数: 4
Position statement of expert panel of the Polish Allergology Sociey on the management of patients with bronchial asthma and allergic diseases during SARS-Cov-2 pandemics. Update 1.06.2020 波兰过敏症学会专家小组关于SARS-Cov-2大流行期间支气管哮喘和过敏性疾病患者管理的立场声明更新1.06.2020
IF 0.2 Pub Date : 2020-01-01 DOI: 10.5114/pja.2020.99242
M. Kowalski, Z. Bartuzi, A. Bręborowicz, E. Cichocka-Jarosz, M. Czarnecka-Operacz, J. Kruszewski, M. Kulus, M. Kupczyk, M. Moniuszko, M. Niedoszytko, M. Nittner-Marszalska, R. Nowicki, B. Rogala, M. Chałubiński
The Polish Allergology Society is one of the first to convene a panel of experts, who on March 30, 2020 presented a position on the management of patients with asthma and allergic diseases during the SARS-CoV-2 pandemic Most of the recommendations and opinions presented in this position remain valid until now However, the dynamically changing epidemiological situation associated with SARS-CoV-2 infection poses new challenges for physicians in the care of asthma and allergic diseases Numerous published clinical observations and studies provide new information on asthma and allergic diseases in relation to the COVID-19 pandemic The current document contains new recommendations in line with available knowledge and taking into ac-count the views of other national and international organizations and societies
波兰过敏症学会是最早召集专家小组的组织之一,该小组于2020年3月30日就SARS-CoV-2大流行期间哮喘和过敏性疾病患者的管理提出了立场,该立场中提出的大多数建议和意见到目前为止仍然有效。与SARS-CoV-2感染相关的动态变化的流行病学形势给哮喘和过敏性疾病的护理医生带来了新的挑战。大量发表的临床观察和研究提供了与COVID-19大流行相关的哮喘和过敏性疾病的新信息。本文件根据现有知识并考虑到其他国家和国际组织和学会的观点,包含了新的建议
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引用次数: 0
Skin prick test and patient informed consent 皮肤点刺试验和患者知情同意
IF 0.2 Pub Date : 2020-01-01 DOI: 10.5114/pja.2020.93831
R. Pawliczak
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引用次数: 1
Severe uncontrolled allergic eosinophilic asthma – looking for the best therapeutic option 严重不受控制的过敏性嗜酸性哮喘-寻找最佳治疗方案
IF 0.2 Pub Date : 2020-01-01 DOI: 10.5114/pja.2020.101997
I. Kupryś-Lipińska, P. Kuna
In this article the authors analyze in detail the clinical role of immunoglobulins E and eosinophils in the etiology and pathogenesis of asthma, and their impact on the course of asthma. They discuss problems related to the treatment of severe bronchial asthma and new therapeutic options. They recall the positions of experts on the criteria for qualifying for biological therapies and discuss the order of drug use, especially in the group of patients presenting simultaneously the phenotype of allergic and eosinophilic asthma.
本文详细分析了免疫球蛋白E和嗜酸性粒细胞在哮喘病因病机中的临床作用及其对哮喘病程的影响。他们讨论了与治疗严重支气管哮喘和新的治疗方案有关的问题。他们回顾了专家对生物治疗资格标准的立场,并讨论了药物使用顺序,特别是在同时出现过敏性和嗜酸性哮喘表型的患者组中。
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引用次数: 0
Expert group commentary on the international recommendation for management of urticaria: The EAACI/GA2LEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria [Allergy 2018; 73: 1393-1414] 国际荨麻疹管理建议专家组评论:EAACI/GA2LEN/EDF/WAO荨麻疹定义、分类、诊断和管理指南[Allergy 2018;73: 1393 - 1414)
IF 0.2 Pub Date : 2020-01-01 DOI: 10.5114/pja.2020.93828
Z. Brzoza, Z. Bartuzi, M. Czarnecka-Operacz, K. Jahnz-Różyk, M. Kulus, J. Narbutt
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引用次数: 3
Estimated COVID-19 IFR was dozen times higher than flu IFR, whereas COVID-19 CFR was several dozen times higher than flu CFR in USA 在美国,估计的COVID-19 IFR比流感IFR高几十倍,而COVID-19 CFR比流感CFR高几十倍
IF 0.2 Pub Date : 2020-01-01 DOI: 10.5114/pja.2020.102088
P. Rieske
There is a dispute over whether COVID-19 is more deadly than the flu Disease mortality does not have to be a parameter that correctly describes the threat Sometimes population mortality does it better However this parameter can be calculated after all and does not help to prevent spread of new disease such as COVID-19 Unfortunately, the IFR for influenza is difficult to calculate Nevertheless, this study makes such an attempt for the USA This was possible in the case of the USA because it is a country that monitors both diseases relatively well According to these data, the estimated IFR (infection fatality rate) for COVID-19 was approximately 15 times higher than for influenza, whereas CFR (case fatality rate) was approximately 60 times for COVID-19 than for flu
关于COVID-19是否比流感更致命存在争议疾病死亡率不一定是正确描述威胁的参数有时人口死亡率会更好,但该参数毕竟可以计算,并且无助于防止COVID-19等新疾病的传播不幸的是,流感的IFR很难计算。这项研究为美国做了这样的尝试,这在美国是可能的,因为它是一个监测这两种疾病相对较好的国家。根据这些数据,估计COVID-19的IFR(感染致死率)大约是流感的15倍,而CFR(病死率)大约是流感的60倍
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引用次数: 0
The role of assay for allergen specific immunoglobulin G in the diagnosis of food allergy and intolerance 过敏原特异性免疫球蛋白G测定在食物过敏和不耐受诊断中的作用
IF 0.2 Pub Date : 2020-01-01 DOI: 10.5114/pja.2020.96127
Z. Bartuzi, K. Lis, M. Żbikowska-Gotz
Adverse post-food reactions can manifest themselves both within a few minutes after contact with harmful food, as well as several or several dozen hours after eating potentially allergenic food protein. They can also cover a very wide spectrum of clinical symptoms, both mild or restricted, as well as very severe systemic re-
不良的食后反应既可以在接触有害食物后的几分钟内表现出来,也可以在食用可能引起过敏的食物蛋白质后的几小时或几十小时内表现出来。它们还可以涵盖非常广泛的临床症状,无论是轻度的还是限制性的,以及非常严重的系统性复发
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引用次数: 2
Allergic rhinitis and central nervous system disorders 过敏性鼻炎和中枢神经系统疾病
IF 0.2 Pub Date : 2020-01-01 DOI: 10.5114/pja.2020.96128
G. Walkiewicz, Marta Sobolczyk, R. Pawliczak
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引用次数: 0
期刊
Alergologia Polska - Polish Journal of Allergology
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