Pub Date : 2022-01-01DOI: 10.21608/adjg.2021.39074.1287
Nehal Abosamra, Heba Eltayeb, Fatma Abdul-Rahman
Purpose: The purpose of this study was to evaluate & compare the remineralization potential of two remineralizing agents on artificially induced enamel carious lesions via pH cycling. This assessment has been conducted via Surface microhardness analysis and energy dispersive X-ray(EDX) analysis. Materials and Methods: In this in vitro study, 20 human teeth were sectioned mesio-distally to obtain 40 enamel samples where artificial carious lesions were induced using an acidic buffer solution. Then samples were randomly divided into two groups (n=20) according to the material used. The first group was for Casein phosphopeptide–amorphous calcium phosphate(CPP-ACP) &the second was for Nano-hydroxyapatite paste(nHAP). Each group was further subdivided into two subgroups(n=10) according to whether subjected to pH cycling or not. The surface microhardness was measured for enamel by Vickers hardness tester at baseline, demineralization and after the application of remineralizing agents in a 15days pH-cycling model and without it. Similarly, the mineral content of the samples was estimated by EDX analysis. The data were analyzed using independent t-test, ANOVA test and Tukey’s post-hoc test. Results: Results of the microhardness showed that without pH cycling; CPP-ACP recorded a higher statistically significant difference than nHAP. Additionally, after pH cycling, CPP-ACP recorded a non-significant difference than nHAP. Moreover, EDX results revealed that the Ca/P ratio for the nHAP group recorded the highest statistically significant difference than all tested groups followed by CPP-ACP without pH cycling, baseline and CPP-ACP after pH cycling, respectively. Conclusion: CPP-ACP and nHAP both had a positive effect on causing remineralization of enamel. Nano-hydroxyapatite was more effective as compared to CPP-ACP, in increasing the calcium and phosphorus content of enamel in both presence and absence of pH cycling. Codex : 01/22.01 azhardentj@azhar.edu.eg http://adjg.journals.ekb.eg DOI: 10.21608/adjg.2021.39074.1287 Restorative Dentistry (Removable Prosthodontics, Fixed Prosthodontics, Endodontics, Dental Biomaterials, Operative Dentistry)
{"title":"Evaluation of Remineralization Potential of Two Agents and pH Cycling on Early Enamel Lesions","authors":"Nehal Abosamra, Heba Eltayeb, Fatma Abdul-Rahman","doi":"10.21608/adjg.2021.39074.1287","DOIUrl":"https://doi.org/10.21608/adjg.2021.39074.1287","url":null,"abstract":"Purpose: The purpose of this study was to evaluate & compare the remineralization potential of two remineralizing agents on artificially induced enamel carious lesions via pH cycling. This assessment has been conducted via Surface microhardness analysis and energy dispersive X-ray(EDX) analysis. Materials and Methods: In this in vitro study, 20 human teeth were sectioned mesio-distally to obtain 40 enamel samples where artificial carious lesions were induced using an acidic buffer solution. Then samples were randomly divided into two groups (n=20) according to the material used. The first group was for Casein phosphopeptide–amorphous calcium phosphate(CPP-ACP) &the second was for Nano-hydroxyapatite paste(nHAP). Each group was further subdivided into two subgroups(n=10) according to whether subjected to pH cycling or not. The surface microhardness was measured for enamel by Vickers hardness tester at baseline, demineralization and after the application of remineralizing agents in a 15days pH-cycling model and without it. Similarly, the mineral content of the samples was estimated by EDX analysis. The data were analyzed using independent t-test, ANOVA test and Tukey’s post-hoc test. Results: Results of the microhardness showed that without pH cycling; CPP-ACP recorded a higher statistically significant difference than nHAP. Additionally, after pH cycling, CPP-ACP recorded a non-significant difference than nHAP. Moreover, EDX results revealed that the Ca/P ratio for the nHAP group recorded the highest statistically significant difference than all tested groups followed by CPP-ACP without pH cycling, baseline and CPP-ACP after pH cycling, respectively. Conclusion: CPP-ACP and nHAP both had a positive effect on causing remineralization of enamel. Nano-hydroxyapatite was more effective as compared to CPP-ACP, in increasing the calcium and phosphorus content of enamel in both presence and absence of pH cycling. Codex : 01/22.01 azhardentj@azhar.edu.eg http://adjg.journals.ekb.eg DOI: 10.21608/adjg.2021.39074.1287 Restorative Dentistry (Removable Prosthodontics, Fixed Prosthodontics, Endodontics, Dental Biomaterials, Operative Dentistry)","PeriodicalId":7493,"journal":{"name":"Al-Azhar Dental Journal for Girls","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89617504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.21608/adjg.2021.64304.1342
Mahetab Montaser, F. Khalifa, F. Mohamed, W. Shawkat
Purpose: to evaluate the symmetry of the reduced unilateral zygomaticomaxillary complex (ZMC) fractures fixed with computer designed custom machined titanium miniplate and conventional titanium miniplate, using three dimensional computed tomography (3D-CT) analysis of ZMC position. Patients and Methods: Ten patients who suffered from unilateral ZMC fractured were involved in this study. The patients were randomly and equally divided into two groups. In group A, the ZMC fractures were reduced and fixed with computer designed custom machined titanium miniplates, whereas in group B, they were fixed by conventional 2.0mm titanium miniplates. Computed Tomography (CT) scan was performed for each patient pre and postoperatively, then imported as a Digital imaging communication in medicine (DICOM) to MIMICS software to make Standard tessellation language(STL) file for quantitative measurements, preoperative surgical planning was performed to group A for designing of custom made plates by mirror imaging of the unaffected side, segmentation and virtual reduction using PlastyCAD software, then fabrication of the final design of the plate by Computer numerically controlled (CNC) milling machines. Results: Clinical symmetry was achieved in all cases except two in group B. By radiographic analysis, there was a significant difference between the two groups. Group A showed smaller deviation from the unaffected side, indicating more adequate reduction in group A than group B. Conclusion: Custom made plate revealed adequate accuracy in restoring ZMC symmetry than conventional miniplates. The 3-D quantitative assessment used in this study successfully reflected symmetry levels Codex : 14/22.01 azhardentj@azhar.edu.eg http://adjg.journals.ekb.eg DOI: 10.21608/adjg.2021.64304.1342 Oral Medicine & Surgical Sciences (Oral Medicine, Oral & Maxillofacial Surgery, Oral Pathology, Oral Biology)
{"title":"Three-dimensional Measuring of Zygomaticomaxillary Complex Symmetry after Fixation of Unilateral Zygomaticomaxillary Complex Fracture","authors":"Mahetab Montaser, F. Khalifa, F. Mohamed, W. Shawkat","doi":"10.21608/adjg.2021.64304.1342","DOIUrl":"https://doi.org/10.21608/adjg.2021.64304.1342","url":null,"abstract":"Purpose: to evaluate the symmetry of the reduced unilateral zygomaticomaxillary complex (ZMC) fractures fixed with computer designed custom machined titanium miniplate and conventional titanium miniplate, using three dimensional computed tomography (3D-CT) analysis of ZMC position. Patients and Methods: Ten patients who suffered from unilateral ZMC fractured were involved in this study. The patients were randomly and equally divided into two groups. In group A, the ZMC fractures were reduced and fixed with computer designed custom machined titanium miniplates, whereas in group B, they were fixed by conventional 2.0mm titanium miniplates. Computed Tomography (CT) scan was performed for each patient pre and postoperatively, then imported as a Digital imaging communication in medicine (DICOM) to MIMICS software to make Standard tessellation language(STL) file for quantitative measurements, preoperative surgical planning was performed to group A for designing of custom made plates by mirror imaging of the unaffected side, segmentation and virtual reduction using PlastyCAD software, then fabrication of the final design of the plate by Computer numerically controlled (CNC) milling machines. Results: Clinical symmetry was achieved in all cases except two in group B. By radiographic analysis, there was a significant difference between the two groups. Group A showed smaller deviation from the unaffected side, indicating more adequate reduction in group A than group B. Conclusion: Custom made plate revealed adequate accuracy in restoring ZMC symmetry than conventional miniplates. The 3-D quantitative assessment used in this study successfully reflected symmetry levels Codex : 14/22.01 azhardentj@azhar.edu.eg http://adjg.journals.ekb.eg DOI: 10.21608/adjg.2021.64304.1342 Oral Medicine & Surgical Sciences (Oral Medicine, Oral & Maxillofacial Surgery, Oral Pathology, Oral Biology)","PeriodicalId":7493,"journal":{"name":"Al-Azhar Dental Journal for Girls","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86899825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.21608/adjg.2021.66174.1346
N. Aidaros, Mona Eliwa, Raghda Kamh
Purpose: The objective of this in vitro study was to evaluate and compare the remineralizing potential of dentifrices containing nanohydroxyapatite, fluoride, and bioactive glass with and without fluoride on enamel by assessing the enamel surface microhardness the enamel structural and elemental analysis through Energy Dispersive X-ray Analysis (EDX). Methods: Sound extracted third molars were divided into 5 groups. Group A (n=15): Hydroxyapatite toothpaste (Karex) was used to treat the teeth; Group B (n=15): teeth were treated with Hydroxyapatite and Fluoride containing toothpaste (Apacare); Group C (n=15): teeth were treated with ChloroCalcium Phosphosilicate containing toothpaste (Biomin C); Group D (n=15): teeth were treated with FluoroCalcium Phosphosilicate containing toothpaste (Biomin F); negative control group (n=15): teeth not subjected to any treatment. All teeth (experimental and negative control groups). After 2 weeks of the dynamic pH-cycling; 10 teeth of each group were subjected to microhardness assessment, while 5 teeth of each group were subjected to EDX Analysis. Results: After 2 weeks of pH-cycling, all experimental groups (A, B, C, and D) showed a percent increase of enamel surface microhardness. Group D reported the highest percent increase (15.07%) while teeth that were not subjected to any treatment (negative control group) showed a percent decrease (-15.7%). Fluoride and calcium ions recorded a significantly higher percent increase in group D, while a significantly lower value was recorded in the control group. Conclusion: All the experimental toothpaste had the potential to remineralize enamel surface subjected to dynamic pH-cycling, but the incorporation of fluoride with the bioactive glass technology as in Biomin F toothpaste had the maximum effect on the demineralized enamel surface. Codex : 08/22.01 azhardentj@azhar.edu.eg http://adjg.journals.ekb.eg DOI: 10.21608/adjg.2021.66174.1346 Restorative Dentistry (Removable Prosthodontics, Fixed Prosthodontics, Endodontics, Dental Biomaterials, Operative Dentistry)
{"title":"Remineralization Efficiency of Different Toothpastes on Human Enamel Subjected to Acid Challenge: in Vitro Study","authors":"N. Aidaros, Mona Eliwa, Raghda Kamh","doi":"10.21608/adjg.2021.66174.1346","DOIUrl":"https://doi.org/10.21608/adjg.2021.66174.1346","url":null,"abstract":"Purpose: The objective of this in vitro study was to evaluate and compare the remineralizing potential of dentifrices containing nanohydroxyapatite, fluoride, and bioactive glass with and without fluoride on enamel by assessing the enamel surface microhardness the enamel structural and elemental analysis through Energy Dispersive X-ray Analysis (EDX). Methods: Sound extracted third molars were divided into 5 groups. Group A (n=15): Hydroxyapatite toothpaste (Karex) was used to treat the teeth; Group B (n=15): teeth were treated with Hydroxyapatite and Fluoride containing toothpaste (Apacare); Group C (n=15): teeth were treated with ChloroCalcium Phosphosilicate containing toothpaste (Biomin C); Group D (n=15): teeth were treated with FluoroCalcium Phosphosilicate containing toothpaste (Biomin F); negative control group (n=15): teeth not subjected to any treatment. All teeth (experimental and negative control groups). After 2 weeks of the dynamic pH-cycling; 10 teeth of each group were subjected to microhardness assessment, while 5 teeth of each group were subjected to EDX Analysis. Results: After 2 weeks of pH-cycling, all experimental groups (A, B, C, and D) showed a percent increase of enamel surface microhardness. Group D reported the highest percent increase (15.07%) while teeth that were not subjected to any treatment (negative control group) showed a percent decrease (-15.7%). Fluoride and calcium ions recorded a significantly higher percent increase in group D, while a significantly lower value was recorded in the control group. Conclusion: All the experimental toothpaste had the potential to remineralize enamel surface subjected to dynamic pH-cycling, but the incorporation of fluoride with the bioactive glass technology as in Biomin F toothpaste had the maximum effect on the demineralized enamel surface. Codex : 08/22.01 azhardentj@azhar.edu.eg http://adjg.journals.ekb.eg DOI: 10.21608/adjg.2021.66174.1346 Restorative Dentistry (Removable Prosthodontics, Fixed Prosthodontics, Endodontics, Dental Biomaterials, Operative Dentistry)","PeriodicalId":7493,"journal":{"name":"Al-Azhar Dental Journal for Girls","volume":"102 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82437418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.21608/adjg.2021.22651.1216
Yousra Saad, A. Salama, S. Ibrahim, Nahed M. Adly, A. M. Abd El Azeem
Purpose:In this study we were aiming to determine and evaluate the efficacy of the stem cells and corticotomy on the rate of canine retraction. Materials and Methods: 22 patients from both genders were selected. The age range of the selected cases was (15-20 years). All patients were examined to fulfill the inclusion criteria. These patients were divided into two groups; control group and intervention group. Split mouth technique was adopted in the intervention group to minimize the variables. In the intervention group one side received piezocorticomy only, while the other side received piezocorticotomy and stem cells. In control group conventional orthodontic canine retraction was carried out. To measure the rate of canine retraction; impression and casts were taken every one month till complete canine retraction. Casts were then digitally scanned and superimposed to digitally measure the rate of canine retraction. Results: Regarding maxilla the results showed no significant difference in the total rate of canine retraction of all comparative groups. Regarding mandible, the difference was significant higher between both stem cell and piezo groups in comparison to the control group. The canine retraction rate was higher in maxilla and mandible with stem cell injection than in the Piezo group of both arches; this difference in maxilla was in the first month of retraction only, but in mandible it was in the first two months. Conclusions: addition of stem cells to piezocorticotomy showed highest canine retraction rate in early months of retraction. Codex : 16/22.01 azhardentj@azhar.edu.eg http://adjg.journals.ekb.eg DOI: 10.21608/adjg.2021.22651.1216 Pediatric Dentistry & Orthodontics ( Pediatric Dentistry, Orthodontics )
{"title":"Efficacy of Stem Cells and Corticotomy on the Rate of Canine Retraction","authors":"Yousra Saad, A. Salama, S. Ibrahim, Nahed M. Adly, A. M. Abd El Azeem","doi":"10.21608/adjg.2021.22651.1216","DOIUrl":"https://doi.org/10.21608/adjg.2021.22651.1216","url":null,"abstract":"Purpose:In this study we were aiming to determine and evaluate the efficacy of the stem cells and corticotomy on the rate of canine retraction. Materials and Methods: 22 patients from both genders were selected. The age range of the selected cases was (15-20 years). All patients were examined to fulfill the inclusion criteria. These patients were divided into two groups; control group and intervention group. Split mouth technique was adopted in the intervention group to minimize the variables. In the intervention group one side received piezocorticomy only, while the other side received piezocorticotomy and stem cells. In control group conventional orthodontic canine retraction was carried out. To measure the rate of canine retraction; impression and casts were taken every one month till complete canine retraction. Casts were then digitally scanned and superimposed to digitally measure the rate of canine retraction. Results: Regarding maxilla the results showed no significant difference in the total rate of canine retraction of all comparative groups. Regarding mandible, the difference was significant higher between both stem cell and piezo groups in comparison to the control group. The canine retraction rate was higher in maxilla and mandible with stem cell injection than in the Piezo group of both arches; this difference in maxilla was in the first month of retraction only, but in mandible it was in the first two months. Conclusions: addition of stem cells to piezocorticotomy showed highest canine retraction rate in early months of retraction. Codex : 16/22.01 azhardentj@azhar.edu.eg http://adjg.journals.ekb.eg DOI: 10.21608/adjg.2021.22651.1216 Pediatric Dentistry & Orthodontics ( Pediatric Dentistry, Orthodontics )","PeriodicalId":7493,"journal":{"name":"Al-Azhar Dental Journal for Girls","volume":"115 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79073714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.21608/adjg.2021.76197.1382
Rehab Osman, Naglaa Elkilani, H. Adawy, M. Attia
Purpose: The main target of our split mouth randomized controlled clinical trial was to evaluate how well laser assisted ridge preservation worked in conjunction with platelet rich fibrin (PRF) and/or bone clinical and radiographically. Subjects and Methods: Thirty extraction sockets from ten patients were split into three groups at random; group I treated by PRF and bone graft after atraumatic extraction, group II (PRF and laser assisted socket preservation) and group III (PRF, bone graft and laser assisted socket preservation). Width and height of the alveolar ridge observed at baseline, three and six months after treatment. Bone density recorded at six months after treatment using cone beam computer tomography (CBCT). Results: The mean ridge width in Groups II and III was statistically significantly higher than in Group I. After three and six months, there was no statistically significant difference between the three groups in ridge height. Group II had a higher mean of bone density. Conclusion: Within the scope of this research, laser-assisted ridge preservation appears to have better clinical and radiographic outcomes following tooth extraction.
{"title":"Evaluation of Laser Assisted Ridge Preservation Combined with Platelet Rich Fibrin and /or Bone","authors":"Rehab Osman, Naglaa Elkilani, H. Adawy, M. Attia","doi":"10.21608/adjg.2021.76197.1382","DOIUrl":"https://doi.org/10.21608/adjg.2021.76197.1382","url":null,"abstract":"Purpose: The main target of our split mouth randomized controlled clinical trial was to evaluate how well laser assisted ridge preservation worked in conjunction with platelet rich fibrin (PRF) and/or bone clinical and radiographically. Subjects and Methods: Thirty extraction sockets from ten patients were split into three groups at random; group I treated by PRF and bone graft after atraumatic extraction, group II (PRF and laser assisted socket preservation) and group III (PRF, bone graft and laser assisted socket preservation). Width and height of the alveolar ridge observed at baseline, three and six months after treatment. Bone density recorded at six months after treatment using cone beam computer tomography (CBCT). Results: The mean ridge width in Groups II and III was statistically significantly higher than in Group I. After three and six months, there was no statistically significant difference between the three groups in ridge height. Group II had a higher mean of bone density. Conclusion: Within the scope of this research, laser-assisted ridge preservation appears to have better clinical and radiographic outcomes following tooth extraction.","PeriodicalId":7493,"journal":{"name":"Al-Azhar Dental Journal for Girls","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83299633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.21608/adjg.2021.29662.1259
Mai Okasha, M. Mostafa, salam El-Araby
Purpose The aim of study was to evaluate antibacterial effect of Rosemarinus officinalis extract on Streptococcus Mutans in group of Egyptian children in comparison with gold standard chlorhexidine. Subjects and Methods: Total of 40 Egyptian children with no sex predilection included in this study. Children’s ages ranged from 6 to 12 years. Children divided into 2 groups A and B. Group A (experimental group): 20 children instructed to rinse with 5ml of R. officinalis extract twice per day for 2 weeks 30 seconds/rinse. Group B (control group): 20 children instructed to rinse with 5ml of Chlorhexidine (0.12 %) twice per day for 2 weeks 30 seconds/rinse. Results: In both groups there was statistically significant reduction in Streptococcus Mutans counts were obtained but the reduction was found slightly higher in chlorhexidine group. Conclusions: The use of Rosmarinus officinalis extract in children is safer than chlorhexidine because rosemary is natural herb that does not contain any chemicals.
{"title":"Evaluation of Antibacterial Effect of Rosmarinus Officinalis Extract on Streptococcus Mutans in Children","authors":"Mai Okasha, M. Mostafa, salam El-Araby","doi":"10.21608/adjg.2021.29662.1259","DOIUrl":"https://doi.org/10.21608/adjg.2021.29662.1259","url":null,"abstract":"Purpose The aim of study was to evaluate antibacterial effect of Rosemarinus officinalis extract on Streptococcus Mutans in group of Egyptian children in comparison with gold standard chlorhexidine. Subjects and Methods: Total of 40 Egyptian children with no sex predilection included in this study. Children’s ages ranged from 6 to 12 years. Children divided into 2 groups A and B. Group A (experimental group): 20 children instructed to rinse with 5ml of R. officinalis extract twice per day for 2 weeks 30 seconds/rinse. Group B (control group): 20 children instructed to rinse with 5ml of Chlorhexidine (0.12 %) twice per day for 2 weeks 30 seconds/rinse. Results: In both groups there was statistically significant reduction in Streptococcus Mutans counts were obtained but the reduction was found slightly higher in chlorhexidine group. Conclusions: The use of Rosmarinus officinalis extract in children is safer than chlorhexidine because rosemary is natural herb that does not contain any chemicals.","PeriodicalId":7493,"journal":{"name":"Al-Azhar Dental Journal for Girls","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81451086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.21608/adjg.2021.47114.1309
Doaa Habba, Nadia A. Radi, Eman Abo Hager
Purpose: The current research was conducted to estimate the anticarcinogenic effect of sulforaphane (SFN) combined with different doses of the chemotherapeutic agent cisplatin (CIS) on the cell line of Squamous cell carcinoma orally to consider sulforaphane (Broccoli extract) Outcome on cell viability and apoptosis of the oral squamous cell carcinoma cell line. Subjects and Method: Squamous cell carcinoma of the human tongue (SCC9) cell line subcultured to obtain 6 study groups, which were subjected to SFN, CIS with low dose, CIS with high dose and a combination of both (SFN with CIS in low concentration = mix1 and SFN with CIS in high concentration = mix2), one study group of SCC9, not subjected to therapy, was used as a negative control. Using Doses of both SFN, CIS were determined using the MTT viability assay, to calculate their IC50 value. Then, apoptotic analysis, using Caspase3, in different study groups were assessed using RT-PCR. Results: Treatment results have been measured for cell viability, apoptosis and gene expression. In doseand a timedependent way, SFN decreased viability for SCC9 cells. SFN-combined therapy increased CIS cytotoxic activity because low-dose CIS (mix1) SFN was extremely cytotoxic to SCC9 after 72 hours. SFN increased SCC9 apoptosis with a high dose of CIS (mix2) and that process was due to up-regulation of Caspase3. Conclusion: Cytotoxicity against SCC9 cells was increased by combining SFN with low doses of CIS. In the treatment of OSCCC, combined SFN-CIS mixtures have a possible additive mean.
{"title":"Evaluation of Anticarcinogenic Potential of Broccoli Extract on Oral Squamous Cell Carcinoma Cell Line","authors":"Doaa Habba, Nadia A. Radi, Eman Abo Hager","doi":"10.21608/adjg.2021.47114.1309","DOIUrl":"https://doi.org/10.21608/adjg.2021.47114.1309","url":null,"abstract":"Purpose: The current research was conducted to estimate the anticarcinogenic effect of sulforaphane (SFN) combined with different doses of the chemotherapeutic agent cisplatin (CIS) on the cell line of Squamous cell carcinoma orally to consider sulforaphane (Broccoli extract) Outcome on cell viability and apoptosis of the oral squamous cell carcinoma cell line. Subjects and Method: Squamous cell carcinoma of the human tongue (SCC9) cell line subcultured to obtain 6 study groups, which were subjected to SFN, CIS with low dose, CIS with high dose and a combination of both (SFN with CIS in low concentration = mix1 and SFN with CIS in high concentration = mix2), one study group of SCC9, not subjected to therapy, was used as a negative control. Using Doses of both SFN, CIS were determined using the MTT viability assay, to calculate their IC50 value. Then, apoptotic analysis, using Caspase3, in different study groups were assessed using RT-PCR. Results: Treatment results have been measured for cell viability, apoptosis and gene expression. In doseand a timedependent way, SFN decreased viability for SCC9 cells. SFN-combined therapy increased CIS cytotoxic activity because low-dose CIS (mix1) SFN was extremely cytotoxic to SCC9 after 72 hours. SFN increased SCC9 apoptosis with a high dose of CIS (mix2) and that process was due to up-regulation of Caspase3. Conclusion: Cytotoxicity against SCC9 cells was increased by combining SFN with low doses of CIS. In the treatment of OSCCC, combined SFN-CIS mixtures have a possible additive mean.","PeriodicalId":7493,"journal":{"name":"Al-Azhar Dental Journal for Girls","volume":"337 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77997973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.21608/adjg.2021.73464.1356
Nada F. Mohamed, Mohsen Nour El Dein, Heba Abdelkafy
Purpose: To evaluate the efficacy of Apple Vinegar irrigating solution using EndoVac system in removing the smear layer from root canals. Materials and Methods: Fifty extracted permanent mandibular first molar teeth with curved mesiobuccal root canals of 5°-20° curvature range were prepared using ProTaper Gold rotary files. Then, they were divided into three groups, two equal main groups with 20 teeth for each (Group I & Group II) plus one control group (10 teeth), based on the final irrigating solution used. Group I; was rinsed with 17% EDTA, Group II; with Apple vinegar, and the Control group with sterile saline. All groups were further subdivided into two equal subgroups (A&B) according to irrigating device where Subgroup A: conventional irrigation, and Subgroup B: EndoVac irrigation system. All teeth were prepared for smear layer examination using a scanning electron microscope. Results: There was no statistically significant difference between Apple Vinegar and 17% EDTA groups at all root canal levels with either conventional or EndoVac irrigation. However, at the apical level, EndoVac irrigation system was superior to conventional technique when apple vinegar was the irrigant used with a statistically significant difference (p=0.029). Conclusion: Apple vinegar is as effective as 17% EDTA in smear layer removal from the root canal when used as a final rinse. EndoVac irrigation can help in smear layer removal from intraradicular dentin, especially at the apical root level. Recommendations: Further studies can be done comparing EndoVac system with more recent irrigating devices using apple vinegar as a final rinse. Codex : 09/22.01 azhardentj@azhar.edu.eg http://adjg.journals.ekb.eg DOI: 10.21608/adjg.2021.73464.1356 Restorative Dentistry (Removable Prosthodontics, Fixed Prosthodontics, Endodontics, Dental Biomaterials, Operative Dentistry)
{"title":"Efficacy of Apple Vinegar as Root Canal Irrigant in Removing Smear Layer in Curved Canals Using EndoVac Irrigation System","authors":"Nada F. Mohamed, Mohsen Nour El Dein, Heba Abdelkafy","doi":"10.21608/adjg.2021.73464.1356","DOIUrl":"https://doi.org/10.21608/adjg.2021.73464.1356","url":null,"abstract":"Purpose: To evaluate the efficacy of Apple Vinegar irrigating solution using EndoVac system in removing the smear layer from root canals. Materials and Methods: Fifty extracted permanent mandibular first molar teeth with curved mesiobuccal root canals of 5°-20° curvature range were prepared using ProTaper Gold rotary files. Then, they were divided into three groups, two equal main groups with 20 teeth for each (Group I & Group II) plus one control group (10 teeth), based on the final irrigating solution used. Group I; was rinsed with 17% EDTA, Group II; with Apple vinegar, and the Control group with sterile saline. All groups were further subdivided into two equal subgroups (A&B) according to irrigating device where Subgroup A: conventional irrigation, and Subgroup B: EndoVac irrigation system. All teeth were prepared for smear layer examination using a scanning electron microscope. Results: There was no statistically significant difference between Apple Vinegar and 17% EDTA groups at all root canal levels with either conventional or EndoVac irrigation. However, at the apical level, EndoVac irrigation system was superior to conventional technique when apple vinegar was the irrigant used with a statistically significant difference (p=0.029). Conclusion: Apple vinegar is as effective as 17% EDTA in smear layer removal from the root canal when used as a final rinse. EndoVac irrigation can help in smear layer removal from intraradicular dentin, especially at the apical root level. Recommendations: Further studies can be done comparing EndoVac system with more recent irrigating devices using apple vinegar as a final rinse. Codex : 09/22.01 azhardentj@azhar.edu.eg http://adjg.journals.ekb.eg DOI: 10.21608/adjg.2021.73464.1356 Restorative Dentistry (Removable Prosthodontics, Fixed Prosthodontics, Endodontics, Dental Biomaterials, Operative Dentistry)","PeriodicalId":7493,"journal":{"name":"Al-Azhar Dental Journal for Girls","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86781205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.21608/adjg.2022.113137.1462
H. Elkhodary
Purpose: To compare outcomes of dental treatment under general anesthesia for special health care need and healthy children in a population in Saudi Arabia and to determine whether the patient medical history affects the failure rates of procedures performed under general anesthesia. Subjects and Methods: The records for children who had rehabilitation between 2017 and 2018 and attended the follow up visits for two years following their general anesthesia were examined. Data regarding restoration failures were statistically analyzed. Results: Special health care need children had significantly more extractions (6.07±3.39) than healthy children (4.92±3.00). For special health care need children less than 6 years of age, the composite strip crown showed 100 % failure rate, whereas the preventive resin restoration showed the highest mean failure rate (85.71±37.80) for healthy children. A higher significant difference was found between mean failure rate of stainless steel crowns (21.28±22.92) among healthy children aged more than 6 years compared to special health care need children (10.68±19.55). Conclusion: Treatment approaches used for special health care need and healthy children under general anesthesia differ significantly, with extraction being the most frequently performed procedure among special health care need children and stainless steel crown being the most commonly performed treatment in healthy children.
{"title":"Effect of Medical History on Different Treatment Modalities in Children Treated under General Anesthesia: A Retrospective Study","authors":"H. Elkhodary","doi":"10.21608/adjg.2022.113137.1462","DOIUrl":"https://doi.org/10.21608/adjg.2022.113137.1462","url":null,"abstract":"Purpose: To compare outcomes of dental treatment under general anesthesia for special health care need and healthy children in a population in Saudi Arabia and to determine whether the patient medical history affects the failure rates of procedures performed under general anesthesia. Subjects and Methods: The records for children who had rehabilitation between 2017 and 2018 and attended the follow up visits for two years following their general anesthesia were examined. Data regarding restoration failures were statistically analyzed. Results: Special health care need children had significantly more extractions (6.07±3.39) than healthy children (4.92±3.00). For special health care need children less than 6 years of age, the composite strip crown showed 100 % failure rate, whereas the preventive resin restoration showed the highest mean failure rate (85.71±37.80) for healthy children. A higher significant difference was found between mean failure rate of stainless steel crowns (21.28±22.92) among healthy children aged more than 6 years compared to special health care need children (10.68±19.55). Conclusion: Treatment approaches used for special health care need and healthy children under general anesthesia differ significantly, with extraction being the most frequently performed procedure among special health care need children and stainless steel crown being the most commonly performed treatment in healthy children.","PeriodicalId":7493,"journal":{"name":"Al-Azhar Dental Journal for Girls","volume":"67 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84877966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.21608/adjg.2021.48111.1316
N. Hegab, M. Attia, O. Shaker
Purpose: This study was designed to evaluate the resistin levels in gingival crevicular fluid (GCF) of patients suffering from periodontitis and type II diabetes mellitus (TIIDM) after non-surgical periodontal therapy and Azithromycin (AZM) as adjunctive therapy. Subjects and Methods: 48 patients with periodontitis their age ranging between (20-50) years old were selected for this study were divided into three groups: (group I): healthy patients with periodontitis, (group II): controlled TIIDM patients with periodontitis, and (group III): controlled TIIDM patients with periodontitis who were received AZM. All patients received non-surgical periodontal therapy (NSPT) and were examined with the following clinical periodontal parameters which are plaque index (PI), gingival index (GI), probing depth (PD) and clinical attachment level (CAL) at baseline, 1 month and 3 months. Collection of GCF samples was done in all patients at baseline, 4 weeks and 6 weeks. Following the periodontal therapy. Quantification of resistin in human samples was measured using resistin ELISA test. Results: NSPT was found to show relative improvement in all clinical parameters as well as a decline in resistin levels. In addition, GCF levels of resistin, GI and PI showed greater reduction after non-surgical treatment in group III than group I and II with nonsignificant difference. Conclusion: NSPT is found to be effective in the management of periodontitis patients with and without diabetes mellitus and also GCF resistin can be a potential biomarker to detect the periodontal disease condition. Also, adjunctive use of AZM showed clinical benefit to patients with periodontitis by its role on host response modulation. Codex : 13/22.01 azhardentj@azhar.edu.eg http://adjg.journals.ekb.eg DOI: 10.21608/adjg.2021.48111.1316 Oral Medicine & Surgical Sciences (Oral Medicine, Oral & Maxillofacial Surgery, Oral Pathology, Oral Biology)
{"title":"Assessment of Resistin Level Using Azithromycin as an Adjunctive to Non-Surgical Treatment of Periodontitis Patients with Type II Diabetes Mellitus","authors":"N. Hegab, M. Attia, O. Shaker","doi":"10.21608/adjg.2021.48111.1316","DOIUrl":"https://doi.org/10.21608/adjg.2021.48111.1316","url":null,"abstract":"Purpose: This study was designed to evaluate the resistin levels in gingival crevicular fluid (GCF) of patients suffering from periodontitis and type II diabetes mellitus (TIIDM) after non-surgical periodontal therapy and Azithromycin (AZM) as adjunctive therapy. Subjects and Methods: 48 patients with periodontitis their age ranging between (20-50) years old were selected for this study were divided into three groups: (group I): healthy patients with periodontitis, (group II): controlled TIIDM patients with periodontitis, and (group III): controlled TIIDM patients with periodontitis who were received AZM. All patients received non-surgical periodontal therapy (NSPT) and were examined with the following clinical periodontal parameters which are plaque index (PI), gingival index (GI), probing depth (PD) and clinical attachment level (CAL) at baseline, 1 month and 3 months. Collection of GCF samples was done in all patients at baseline, 4 weeks and 6 weeks. Following the periodontal therapy. Quantification of resistin in human samples was measured using resistin ELISA test. Results: NSPT was found to show relative improvement in all clinical parameters as well as a decline in resistin levels. In addition, GCF levels of resistin, GI and PI showed greater reduction after non-surgical treatment in group III than group I and II with nonsignificant difference. Conclusion: NSPT is found to be effective in the management of periodontitis patients with and without diabetes mellitus and also GCF resistin can be a potential biomarker to detect the periodontal disease condition. Also, adjunctive use of AZM showed clinical benefit to patients with periodontitis by its role on host response modulation. Codex : 13/22.01 azhardentj@azhar.edu.eg http://adjg.journals.ekb.eg DOI: 10.21608/adjg.2021.48111.1316 Oral Medicine & Surgical Sciences (Oral Medicine, Oral & Maxillofacial Surgery, Oral Pathology, Oral Biology)","PeriodicalId":7493,"journal":{"name":"Al-Azhar Dental Journal for Girls","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72628074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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