This research aims to find the direct linkage among the Uric acid rates with Endothelin (ET-1), which is considered the indication of endothelial dysfunction or endothelial damage in patients with T2-DM. This study, included 96 patients with T2-DM and 96 controls, the mean age ranged (56.73 ± 9.14), (56.42 ± 8.74) respectively. Results showed a highly significant increase in Endothelin (ET-1) levels, uric acid, urea, and systolic blood pressure (SBP) was observed as compared with the control group, while Diastolic blood pressure (DBP) and body mass (BMI) were not substantially increased. Additionally, a significant positive correlation was found between ET-1 with uric acid, urea, SBP, DBP in patients with T2-DM (p < 0.05). Finally, elevated uric acid levels in older people who have chronic blood pressure are one of the factors influencing the increased release of ET-1, thus the development of cardiovascular disease.
{"title":"Endothelin Level and Its Correlation with Uric Acid in Type 2 Diabetic Multiuse Patients","authors":"Z. Ismail, Z. H. Jawad, Ali Jasim Hammood","doi":"10.23851/mjs.v31i3.849","DOIUrl":"https://doi.org/10.23851/mjs.v31i3.849","url":null,"abstract":"This research aims to find the direct linkage among the Uric acid rates with Endothelin (ET-1), which is considered the indication of endothelial dysfunction or endothelial damage in patients with T2-DM. This study, included 96 patients with T2-DM and 96 controls, the mean age ranged (56.73 ± 9.14), (56.42 ± 8.74) respectively. Results showed a highly significant increase in Endothelin (ET-1) levels, uric acid, urea, and systolic blood pressure (SBP) was observed as compared with the control group, while Diastolic blood pressure (DBP) and body mass (BMI) were not substantially increased. Additionally, a significant positive correlation was found between ET-1 with uric acid, urea, SBP, DBP in patients with T2-DM (p < 0.05). Finally, elevated uric acid levels in older people who have chronic blood pressure are one of the factors influencing the increased release of ET-1, thus the development of cardiovascular disease.","PeriodicalId":7515,"journal":{"name":"Al-Mustansiriyah Journal of Sciences","volume":"1 1","pages":"35-38"},"PeriodicalIF":0.0,"publicationDate":"2020-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91089536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Three simple spectrophotometric methods namely; area under the curve, simultaneous equation method, and modified simultaneous equation method was developed and validated for the determination of Ampyrone with the presence of its acidic product using zero-order spectra without prior separation techniques. The linearity was found in the range of (10-50 mg/L) and (10-55 mg/L) for Ampyrone and its acidic product, respectively. The recovery percentage was found to be in the range from 99.6 to 100.65 for the area under curve method and 96.64 to 104.8 for the simultaneous equation method and its modified version which showed good accuracy and precision for three proposed methods.
{"title":"Different Mathematical Spectrophotometric Methods for Determination of Ampyrone in Presence of Its Acid Degradation Product","authors":"R. F. Abbas","doi":"10.23851/mjs.v31i3.778","DOIUrl":"https://doi.org/10.23851/mjs.v31i3.778","url":null,"abstract":"Three simple spectrophotometric methods namely; area under the curve, simultaneous equation method, and modified simultaneous equation method was developed and validated for the determination of Ampyrone with the presence of its acidic product using zero-order spectra without prior separation techniques. The linearity was found in the range of (10-50 mg/L) and (10-55 mg/L) for Ampyrone and its acidic product, respectively. The recovery percentage was found to be in the range from 99.6 to 100.65 for the area under curve method and 96.64 to 104.8 for the simultaneous equation method and its modified version which showed good accuracy and precision for three proposed methods.","PeriodicalId":7515,"journal":{"name":"Al-Mustansiriyah Journal of Sciences","volume":"10 1","pages":"72-77"},"PeriodicalIF":0.0,"publicationDate":"2020-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81112581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shayma L. Abdulhadi, M. Q. Abdulkadir, M. M. Al-Mudhafar
The pharmacophore 2-aminothiazole has an interesting role in pharmaceutical chemistry as this led to the synthesis of many types of compounds with diverse biological activity. Schiff base derivatives at the same time contribute to drug evolution importantly. In this review, the Schiff base derivatives of 2-aminothiazole formed and some of their metal complexes are being focused on, and the antimicrobial and anticancer activity of them is being illustrated.
{"title":"The Importance of 2-AminoThiazole Schiff Bases as Antimicrobial and Anticancer Agents","authors":"Shayma L. Abdulhadi, M. Q. Abdulkadir, M. M. Al-Mudhafar","doi":"10.23851/mjs.v31i3.865","DOIUrl":"https://doi.org/10.23851/mjs.v31i3.865","url":null,"abstract":"The pharmacophore 2-aminothiazole has an interesting role in pharmaceutical chemistry as this led to the synthesis of many types of compounds with diverse biological activity. Schiff base derivatives at the same time contribute to drug evolution importantly. In this review, the Schiff base derivatives of 2-aminothiazole formed and some of their metal complexes are being focused on, and the antimicrobial and anticancer activity of them is being illustrated.","PeriodicalId":7515,"journal":{"name":"Al-Mustansiriyah Journal of Sciences","volume":"32 1","pages":"46-64"},"PeriodicalIF":0.0,"publicationDate":"2020-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83739512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. R. Raham, A. AL-RUBAIEE, Majida H. Al-kubaisy, S. N. Esmaeel
In the present work, extensive air showers (EAS) effects are described by estimating the longitudinal development model of EAS at very high energies of various cosmic ray particles. The longitudinal development was simulated for charged particles such as gamma, charged pions and charged muons at very high energies 10 17 , 10 18 and 10 19 eV. The simulation was performed using an air shower simulator system (AIRES) version 19.04.0. The effect of primary particles, energies, thinning energy and zenith angle (θ) on the number of charged particles (longitudinal development) produced in the EAS was taken into account. The rapprochement of the estimated longitudinal development of the charged particles such as the charged muons and charged pions with the experimental measurements (AUGER experiment) that gave a good agreement for primary proton at the fixed primary energy 10 19 eV for θ =0˚.
{"title":"Studying the thinning Effect of Longitudinal development in Extensive Air Showers for Primary Proton and Iron Nuclei at Ultra-High Energies","authors":"A. R. Raham, A. AL-RUBAIEE, Majida H. Al-kubaisy, S. N. Esmaeel","doi":"10.23851/mjs.v31i3.843","DOIUrl":"https://doi.org/10.23851/mjs.v31i3.843","url":null,"abstract":"In the present work, extensive air showers (EAS) effects are described by estimating the longitudinal development model of EAS at very high energies of various cosmic ray particles. The longitudinal development was simulated for charged particles such as gamma, charged pions and charged muons at very high energies 10 17 , 10 18 and 10 19 eV. The simulation was performed using an air shower simulator system (AIRES) version 19.04.0. The effect of primary particles, energies, thinning energy and zenith angle (θ) on the number of charged particles (longitudinal development) produced in the EAS was taken into account. The rapprochement of the estimated longitudinal development of the charged particles such as the charged muons and charged pions with the experimental measurements (AUGER experiment) that gave a good agreement for primary proton at the fixed primary energy 10 19 eV for θ =0˚.","PeriodicalId":7515,"journal":{"name":"Al-Mustansiriyah Journal of Sciences","volume":"103 1","pages":"114-118"},"PeriodicalIF":0.0,"publicationDate":"2020-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78085015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In this work, theoretical calculations and simulated data were presented to investigate the effect of the Ar: Hg mixture on electronic plasma coefficients, in addition to study the influence of the electric field and focus on electronic coefficients. The low electric field was chosen in the range (1-1000) Td, and concentrations in a limited range (0.01-0.09) mol. The results showed a clear effect of the electric field on electronic transactions, especially at low levels. These parameters values are higher for high concentrations due to the effect of the electric field on the excitation and ionization energy. In compare to elastic and inelastic collision, and cross-section collision of gas discharges. The results showed good agreement between the original data (using BOLSIG +) and the estimated data in the current work.
{"title":"Simulation Analyses and Investigation of the Induced Electric Field and Ar-Hg Mixture on the Gas Discharge Processes","authors":"Fatima Mohammad Hadi, R. Ali, A. A. Al-Rubaiee","doi":"10.23851/mjs.v31i3.874","DOIUrl":"https://doi.org/10.23851/mjs.v31i3.874","url":null,"abstract":"In this work, theoretical calculations and simulated data were presented to investigate the effect of the Ar: Hg mixture on electronic plasma coefficients, in addition to study the influence of the electric field and focus on electronic coefficients. The low electric field was chosen in the range (1-1000) Td, and concentrations in a limited range (0.01-0.09) mol. The results showed a clear effect of the electric field on electronic transactions, especially at low levels. These parameters values are higher for high concentrations due to the effect of the electric field on the excitation and ionization energy. In compare to elastic and inelastic collision, and cross-section collision of gas discharges. The results showed good agreement between the original data (using BOLSIG +) and the estimated data in the current work.","PeriodicalId":7515,"journal":{"name":"Al-Mustansiriyah Journal of Sciences","volume":"144 1","pages":"126-131"},"PeriodicalIF":0.0,"publicationDate":"2020-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82923753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Recently, the biosynthesis of nanoparticles from bacteria have attracted attention, this study has been made for biosynthesize and characterizes silver nanoparticles (AgNPs) from local clinical isolate Pantoea agglomerans . The ability of those particles to inhibit the virulence factors biofilm and hemolysin produced by some local clinical multidrug-resistant human pathogenes including Acinetobactor haemolyticus , Escherichia coli , Serratia marcescens and Staphylococcus aureus were investigated by treating all of the test isolates with sub-MIC(16 mg/ml) AgNPs. The AgNPs produced were characterized using Atomic Force Microscopy (AFM). Pantoea agglomerans were found to have the ability to synthesize AgNPs at room temperature within 24hrs and were spherical in shape as depicted by AFM. The AgNPs produced exhibited a potential antibiofilm and hemolysin inhibition activities against tested pathogens.
{"title":"Biosynthesis and Characterization of Silver Nanoparticles From Pantoea agglomerans and Some of Their Antibacterial Activities","authors":"Layla Abdul-Hamed Said","doi":"10.23851/mjs.v31i3.361","DOIUrl":"https://doi.org/10.23851/mjs.v31i3.361","url":null,"abstract":"Recently, the biosynthesis of nanoparticles from bacteria have attracted attention, this study has been made for biosynthesize and characterizes silver nanoparticles (AgNPs) from local clinical isolate Pantoea agglomerans . The ability of those particles to inhibit the virulence factors biofilm and hemolysin produced by some local clinical multidrug-resistant human pathogenes including Acinetobactor haemolyticus , Escherichia coli , Serratia marcescens and Staphylococcus aureus were investigated by treating all of the test isolates with sub-MIC(16 mg/ml) AgNPs. The AgNPs produced were characterized using Atomic Force Microscopy (AFM). Pantoea agglomerans were found to have the ability to synthesize AgNPs at room temperature within 24hrs and were spherical in shape as depicted by AFM. The AgNPs produced exhibited a potential antibiofilm and hemolysin inhibition activities against tested pathogens.","PeriodicalId":7515,"journal":{"name":"Al-Mustansiriyah Journal of Sciences","volume":"12 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2020-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78530157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nehad A. Taher, A. S. Husen, Z. Mahmood, Ghanyia J. Shanior
Production of pH-pigment (actinorhodin – like substance) was ascertained from ten Streptomyses isolates. Streptomyses IQ45 isolate was only isolated which produced pH- sensitive pigment. The production of pH-sensitive pigment was detected by fuming over ammonia. After extraction of this antibiotic, a number of physiocochemical characterizations were carried out which involved (IR, UV, MP, CHN-analysis, and solubility test). Indicated that this antibiotic is an actinorhodin-like substance. TLC of the extracted substance showed a single spot with Rf value equivalent to (0.26) which was close to that of actinorhodin. These antibiotics showed inhibitory activity against Staphylococcus aureus similar to that of actinorhodin produced by Streptomyces coelicolor A3 (2). The productivity of this antibiotics was (45 mg/L) at pH 8.5 and (40 mg/L) at pH 7 from the mycelial mat and (10 mg/L) when extracted from the liquid medium at pH7.
{"title":"A Study on Actinorhodin-like Substance Production by Streptomyces IQ45","authors":"Nehad A. Taher, A. S. Husen, Z. Mahmood, Ghanyia J. Shanior","doi":"10.23851/mjs.v31i3.93","DOIUrl":"https://doi.org/10.23851/mjs.v31i3.93","url":null,"abstract":"Production of pH-pigment (actinorhodin – like substance) was ascertained from ten Streptomyses isolates. Streptomyses IQ45 isolate was only isolated which produced pH- sensitive pigment. The production of pH-sensitive pigment was detected by fuming over ammonia. After extraction of this antibiotic, a number of physiocochemical characterizations were carried out which involved (IR, UV, MP, CHN-analysis, and solubility test). Indicated that this antibiotic is an actinorhodin-like substance. TLC of the extracted substance showed a single spot with Rf value equivalent to (0.26) which was close to that of actinorhodin. These antibiotics showed inhibitory activity against Staphylococcus aureus similar to that of actinorhodin produced by Streptomyces coelicolor A3 (2). The productivity of this antibiotics was (45 mg/L) at pH 8.5 and (40 mg/L) at pH 7 from the mycelial mat and (10 mg/L) when extracted from the liquid medium at pH7.","PeriodicalId":7515,"journal":{"name":"Al-Mustansiriyah Journal of Sciences","volume":"12 1","pages":"6-13"},"PeriodicalIF":0.0,"publicationDate":"2020-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83627411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The study analyzed the optical response of GaAs 0.75 Sb 0.25 nanosheet under high pressure. It is the generalized gradient approximation (GGA) within the framework of density functional theory (DFT) was employed by means of a simulation program, which is called CASTEP. Under different pressure (P = 0, 2, and 4 GPa). Geometry optimized parameters were calculated for the nanosheet. The optical data alter in accordance with high pressure. The increase of pressure in the nanosheet led to a rise in p = 4 GPa and a decline in p = 2 GPa of the optical energy band gap, the static dielectric constant 𝜀 1 (0), and optical conductivity. The discussions of the real 𝜀 1 (𝜔) and imaginary 𝜀 2 (𝜔) sections of the dielectric function, optical band gap energy, optical absorption, and optical conductivity were included.
{"title":"Optical Response of GaAs0.75Sb0.25 Nanosheet for Dependent Pressure","authors":"M. Othman","doi":"10.23851/mjs.v31i3.864","DOIUrl":"https://doi.org/10.23851/mjs.v31i3.864","url":null,"abstract":"The study analyzed the optical response of GaAs 0.75 Sb 0.25 nanosheet under high pressure. It is the generalized gradient approximation (GGA) within the framework of density functional theory (DFT) was employed by means of a simulation program, which is called CASTEP. Under different pressure (P = 0, 2, and 4 GPa). Geometry optimized parameters were calculated for the nanosheet. The optical data alter in accordance with high pressure. The increase of pressure in the nanosheet led to a rise in p = 4 GPa and a decline in p = 2 GPa of the optical energy band gap, the static dielectric constant 𝜀 1 (0), and optical conductivity. The discussions of the real 𝜀 1 (𝜔) and imaginary 𝜀 2 (𝜔) sections of the dielectric function, optical band gap energy, optical absorption, and optical conductivity were included.","PeriodicalId":7515,"journal":{"name":"Al-Mustansiriyah Journal of Sciences","volume":"76 1","pages":"120-125"},"PeriodicalIF":0.0,"publicationDate":"2020-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72987791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The random key plays a basic role in the design of any cryptographic algorithms. In this paper, a proposed model for generating a random key is presented, which will be used for security purposes. Chicken swarm optimization (CSO) and HTML parser are used for scattering the bits of the key. The statistical tests of randomness have given good and acceptable security results. The proposed key generation method was programmed by JavaScript language.
{"title":"Propose a new approach for key generation based on Chicken Swarm Optimization and HTML Parser","authors":"S. Malalla, Ayat Hadi Ali","doi":"10.23851/mjs.v31i3.728","DOIUrl":"https://doi.org/10.23851/mjs.v31i3.728","url":null,"abstract":"The random key plays a basic role in the design of any cryptographic algorithms. In this paper, a proposed model for generating a random key is presented, which will be used for security purposes. Chicken swarm optimization (CSO) and HTML parser are used for scattering the bits of the key. The statistical tests of randomness have given good and acceptable security results. The proposed key generation method was programmed by JavaScript language.","PeriodicalId":7515,"journal":{"name":"Al-Mustansiriyah Journal of Sciences","volume":"7 1","pages":"89-94"},"PeriodicalIF":0.0,"publicationDate":"2020-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72710682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Polycyclic aromatic hydrocarbons (PAHs) are recognized as a toxic, mutagenic and/or carcinogenic compounds, and their pollution of soil and aquifer is of increasing environmentally risk. Laccases (E.C. 1.10.3.2) are phenoloxidases catalyze the oxidation of PAHs in the presence of a mediator compound and hyacinth plant. In this study laccase from Trametes versicolor was immobilized into chitosan, and the potential to oxidize anthracene in the presence of 1-hydroxybenzotriazole (HBT) was examined. Results indicated that the immobilization enhanced the stability of laccase against temperature, pH, inhibitors and loading time compared with the other cases. The immobilized laccase-mediator system was as efficient as the free enzyme for oxidizing the tested PAHs. After 24h. of incubation, immobilized laccase–HBT showed a system oxidization more than immobilized laccase without (HBT) of PAHs; Chitosan with hyacinth plant and (HBT) resulted better conversion than chitosan with or without HBT. These results indicate a new chance for applying the immobilized laccase in bioremediation.
{"title":"Degradation of Anthracene by Immobilizing Laccase From Trametes Versicolor onto Chitosan Beads and Hyacinth Plant","authors":"A. Taha, N. Hameed, F. Ali","doi":"10.23851/mjs.v31i3.670","DOIUrl":"https://doi.org/10.23851/mjs.v31i3.670","url":null,"abstract":"Polycyclic aromatic hydrocarbons (PAHs) are recognized as a toxic, mutagenic and/or carcinogenic compounds, and their pollution of soil and aquifer is of increasing environmentally risk. Laccases (E.C. 1.10.3.2) are phenoloxidases catalyze the oxidation of PAHs in the presence of a mediator compound and hyacinth plant. In this study laccase from Trametes versicolor was immobilized into chitosan, and the potential to oxidize anthracene in the presence of 1-hydroxybenzotriazole (HBT) was examined. Results indicated that the immobilization enhanced the stability of laccase against temperature, pH, inhibitors and loading time compared with the other cases. The immobilized laccase-mediator system was as efficient as the free enzyme for oxidizing the tested PAHs. After 24h. of incubation, immobilized laccase–HBT showed a system oxidization more than immobilized laccase without (HBT) of PAHs; Chitosan with hyacinth plant and (HBT) resulted better conversion than chitosan with or without HBT. These results indicate a new chance for applying the immobilized laccase in bioremediation.","PeriodicalId":7515,"journal":{"name":"Al-Mustansiriyah Journal of Sciences","volume":"16 1","pages":"14-20"},"PeriodicalIF":0.0,"publicationDate":"2020-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89955041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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