首页 > 最新文献

American Journal of Scientific and Industrial Research最新文献

英文 中文
Analysis of spring water quality in Ebonyi South Zone and its health impact 鄂邦义南区泉水水质分析及其健康影响
Pub Date : 2013-04-01 DOI: 10.5251/AJSIR.2013.4.2.231.237
J. Afiukwa, A. Eboatu
Studies were carried out between June through December, 2007 to evaluate the quality of rural water supply for drinking in Ebonyi South Zone of Ebonyi State, Nigeria. The rural communities of Ekoli Edda and Ozizza in Afikpo South L.G.A and parts of Okposi in Ohaozara L.G.A depend solely on spring water for their domestic needs. Samples from seven spring water sources in these areas were analyzed for some physico-chemical and microbial parameters by standard methods. Concentrations of some heavy metals; Cr, Cd, Co, Cu, Fe, Mn, Pb, Ni and Zn were determined using Atomic Absorption Spectrophotometer. The results of the chemical analysis compared favourably with the WHO standard for drinking water, except for the relatively high concentration of iron in samples SE 5 (0.79 mg/L) and SE 6 (0.58 mg/L), and the exceedingly high phosphate concentrations, ranging from 0.25 - 1.6mg/L in all the samples as against the WHO permissible limit of 0.1mg/L. The bacteriological analyses however revealed about 40% total coliform bacteria contamination, varying between 0 - 4 MPN/100 ml of water in five out of the seven samples tested. The mean total hardness ranged from 8 - 26 mgCaCO3 /L indicating that the water is soft. The pH ranged from 4.2 - 5.6 and 4.5 - 6.0 at the rainy and dry seasons respectively, with an average pH of 5.1 + 0.48 during the rainy seasons and 5.6 + 0.58 at the dry seasons. This study provides baseline information on the spring water situation in Ebonyi South and suggested an alternative method of harnessing the natural water.
2007年6月至12月期间进行了研究,以评估尼日利亚埃邦伊州埃邦伊南部地区的农村饮用水供应质量。Afikpo South l.g.a.的Ekoli Edda和Ozizza的农村社区以及Ohaozara l.g.a.的Okposi部分地区完全依靠泉水满足其家庭需求。采用标准方法对该地区7个水源地的水样进行了理化和微生物参数分析。某些重金属的浓度;用原子吸收分光光度法测定了Cr、Cd、Co、Cu、Fe、Mn、Pb、Ni、Zn。化学分析的结果与世界卫生组织的饮用水标准相比是有利的,除了样品SE 5 (0.79 mg/L)和SE 6 (0.58 mg/L)中的铁浓度相对较高,以及磷酸盐浓度极高,所有样品的浓度在0.25 - 1.6mg/L之间,而世界卫生组织允许的限值为0.1mg/L。然而,细菌学分析显示,在7个测试样本中,有5个样本的大肠杆菌污染总量约为40%,在0 - 4 MPN/100毫升水之间变化。平均总硬度在8 - 26 mgCaCO3 /L之间,表明水是软的。雨季和旱季的pH值分别为4.2 ~ 5.6和4.5 ~ 6.0,雨季和旱季的平均pH值分别为5.1 + 0.48和5.6 + 0.58。本研究提供了乌邦伊南部泉水状况的基线信息,并提出了一种利用天然水的替代方法。
{"title":"Analysis of spring water quality in Ebonyi South Zone and its health impact","authors":"J. Afiukwa, A. Eboatu","doi":"10.5251/AJSIR.2013.4.2.231.237","DOIUrl":"https://doi.org/10.5251/AJSIR.2013.4.2.231.237","url":null,"abstract":"Studies were carried out between June through December, 2007 to evaluate the quality of rural water supply for drinking in Ebonyi South Zone of Ebonyi State, Nigeria. The rural communities of Ekoli Edda and Ozizza in Afikpo South L.G.A and parts of Okposi in Ohaozara L.G.A depend solely on spring water for their domestic needs. Samples from seven spring water sources in these areas were analyzed for some physico-chemical and microbial parameters by standard methods. Concentrations of some heavy metals; Cr, Cd, Co, Cu, Fe, Mn, Pb, Ni and Zn were determined using Atomic Absorption Spectrophotometer. The results of the chemical analysis compared favourably with the WHO standard for drinking water, except for the relatively high concentration of iron in samples SE 5 (0.79 mg/L) and SE 6 (0.58 mg/L), and the exceedingly high phosphate concentrations, ranging from 0.25 - 1.6mg/L in all the samples as against the WHO permissible limit of 0.1mg/L. The bacteriological analyses however revealed about 40% total coliform bacteria contamination, varying between 0 - 4 MPN/100 ml of water in five out of the seven samples tested. The mean total hardness ranged from 8 - 26 mgCaCO3 /L indicating that the water is soft. The pH ranged from 4.2 - 5.6 and 4.5 - 6.0 at the rainy and dry seasons respectively, with an average pH of 5.1 + 0.48 during the rainy seasons and 5.6 + 0.58 at the dry seasons. This study provides baseline information on the spring water situation in Ebonyi South and suggested an alternative method of harnessing the natural water.","PeriodicalId":7661,"journal":{"name":"American Journal of Scientific and Industrial Research","volume":"8 15 1","pages":"231-237"},"PeriodicalIF":0.0,"publicationDate":"2013-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80449370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Digital signal processing to simulate heart beats as a medical education tools 将数字信号处理作为模拟心脏跳动的医学教育工具
Pub Date : 2013-04-01 DOI: 10.5251/AJSIR.2013.4.2.191.194
S. Jastaniah, W. Shirbeeny, B. Shakhreet
We explore new methods for medical education using digital signal processing to simulate heart beats and compare normal and abnormal heart pulses. In this work the healthy heart is replaced by a fixed heart-like pulse generator as an AD/DA converter. A visual basic code with friendly interface is written for this purpose. Additionally, abnormal heart beat corresponding to different heart disease were simulated using a waveform generator that allowed production of variable signals we stored in its library. Both of the normal and abnormal heart pulses were displayed using PC oscilloscope. Medical students are allowed to select the heart beats from a drop menu for diseases and compare the characteristics e.g. time intervals, pulse amplitudes and pulse shape deformation with the already displayed healthy heart beats. We believe our teaching methodology enhances the way knowledge are introduced to students in order to meet their educational preferences.
探索利用数字信号处理模拟心脏跳动,比较正常与异常心脏搏动的医学教学新方法。在这项工作中,健康的心脏被一个固定的类似心脏的脉冲发生器取代,作为AD/DA转换器。为此编写了具有友好界面的可视化basic代码。此外,使用波形发生器模拟不同心脏病对应的异常心跳,该波形发生器允许产生我们存储在其库中的可变信号。用PC示波器显示正常和异常的心脏搏动。医科学生可以从疾病的下拉菜单中选择心跳,并将其特征(如时间间隔、脉搏幅度和脉搏形状变形)与已经显示的健康心跳进行比较。我们相信我们的教学方法提高了向学生介绍知识的方式,以满足他们的教育偏好。
{"title":"Digital signal processing to simulate heart beats as a medical education tools","authors":"S. Jastaniah, W. Shirbeeny, B. Shakhreet","doi":"10.5251/AJSIR.2013.4.2.191.194","DOIUrl":"https://doi.org/10.5251/AJSIR.2013.4.2.191.194","url":null,"abstract":"We explore new methods for medical education using digital signal processing to simulate heart beats and compare normal and abnormal heart pulses. In this work the healthy heart is replaced by a fixed heart-like pulse generator as an AD/DA converter. A visual basic code with friendly interface is written for this purpose. Additionally, abnormal heart beat corresponding to different heart disease were simulated using a waveform generator that allowed production of variable signals we stored in its library. Both of the normal and abnormal heart pulses were displayed using PC oscilloscope. Medical students are allowed to select the heart beats from a drop menu for diseases and compare the characteristics e.g. time intervals, pulse amplitudes and pulse shape deformation with the already displayed healthy heart beats. We believe our teaching methodology enhances the way knowledge are introduced to students in order to meet their educational preferences.","PeriodicalId":7661,"journal":{"name":"American Journal of Scientific and Industrial Research","volume":"127 1","pages":"191-194"},"PeriodicalIF":0.0,"publicationDate":"2013-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86408291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Purification and Characterization of α and β- Amylases Isolated from Millet ( Pennisetum glaucum ) Malt 谷子(Pennisetum glaucum)麦芽中α和β-淀粉酶的分离纯化及特性研究
Pub Date : 2013-04-01 DOI: 10.5251/AJSIR.2013.4.2.183.190
M. E. Nour, S. Yagoub
The work aimed to study the diastatic power (PD) of millet malt, to purify the α and β – amylases and to characterize these enzymes. In this study the amylolytic activity initiated during the germination of millet was determined. Fourth day of germination of millet grains showed the highest of the amount of diastatic power (DP) (54.00 IOB), no significant variation (P≤ 0.05) between the extraction procedures followed either by distilled water or water with 2% peptone. DEAE-cellulose chromatography was used for the partial purification of α-and β- amylases. The results obtained from the last purification steps is 6.5o fold of α-amylase in fifth day of germination, whereas β-amylase is 37.50 fold in fourth day of germination. These amylases isolated from millet malt have interesting characteristics such as, storage stability of purified α and β- amylases at different temperature (-20 and 4oC) for 56 days. No significant loss (P≤0.05) in the enzymes activity during the storage period for 56 days in - 20oC, whereas the loss of enzyme activity at 4oC during the period of 56 days were 28% for α and 35% for β-amylases. The maximum activity of α-amylase was obtained at temperature 70oC and 50oC for βamylase, it was clear that the α –amylase is more stable than β-amylase. The optimum pH for both α and β- amylases were 5.0 and 5.5 respectively. Therefore, these characterizations meet the prerequisites need for food industry. This work contributed with the advances in biotechnology generating of conditions for application of a new and of low price amylases source.
本研究旨在研究谷子麦芽的消散力,纯化α和β -淀粉酶,并对其进行表征。本研究测定了谷子萌发过程中产生的淀粉水解活性。谷子种子萌发第4天的发芽量(DP)最高(54.00 IOB),蒸馏水和2%蛋白胨水的提取工艺之间无显著差异(P≤0.05)。采用deae -纤维素层析法对α和β-淀粉酶进行部分纯化。最后一步纯化得到的α-淀粉酶在萌发第5天为6.5倍,β-淀粉酶在萌发第4天为37.50倍。从谷子麦芽中分离得到的α -淀粉酶和β-淀粉酶在不同温度(-20℃和4℃)下保存56 d的稳定性。在- 20℃条件下贮藏56 d,酶活性无显著下降(P≤0.05),而在4℃条件下贮藏56 d, α淀粉酶活性下降28%,β-淀粉酶活性下降35%。α-淀粉酶在温度为70℃和50℃时活性最高,α-淀粉酶比β-淀粉酶更稳定。α -淀粉酶和β-淀粉酶的最适pH分别为5.0和5.5。因此,这些表征满足了食品工业的先决条件。这项工作有助于生物技术的进步,为新的廉价淀粉酶来源的应用创造条件。
{"title":"Purification and Characterization of α and β- Amylases Isolated from Millet ( Pennisetum glaucum ) Malt","authors":"M. E. Nour, S. Yagoub","doi":"10.5251/AJSIR.2013.4.2.183.190","DOIUrl":"https://doi.org/10.5251/AJSIR.2013.4.2.183.190","url":null,"abstract":"The work aimed to study the diastatic power (PD) of millet malt, to purify the α and β – amylases and to characterize these enzymes. In this study the amylolytic activity initiated during the germination of millet was determined. Fourth day of germination of millet grains showed the highest of the amount of diastatic power (DP) (54.00 IOB), no significant variation (P≤ 0.05) between the extraction procedures followed either by distilled water or water with 2% peptone. DEAE-cellulose chromatography was used for the partial purification of α-and β- amylases. The results obtained from the last purification steps is 6.5o fold of α-amylase in fifth day of germination, whereas β-amylase is 37.50 fold in fourth day of germination. These amylases isolated from millet malt have interesting characteristics such as, storage stability of purified α and β- amylases at different temperature (-20 and 4oC) for 56 days. No significant loss (P≤0.05) in the enzymes activity during the storage period for 56 days in - 20oC, whereas the loss of enzyme activity at 4oC during the period of 56 days were 28% for α and 35% for β-amylases. The maximum activity of α-amylase was obtained at temperature 70oC and 50oC for βamylase, it was clear that the α –amylase is more stable than β-amylase. The optimum pH for both α and β- amylases were 5.0 and 5.5 respectively. Therefore, these characterizations meet the prerequisites need for food industry. This work contributed with the advances in biotechnology generating of conditions for application of a new and of low price amylases source.","PeriodicalId":7661,"journal":{"name":"American Journal of Scientific and Industrial Research","volume":"35 1","pages":"183-190"},"PeriodicalIF":0.0,"publicationDate":"2013-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82492570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Seroprevalence of parvovirus B19 and its clinical effect among anaemic SCA patients in Northeastern Nigeria 尼日利亚东北部地区SCA贫血患者细小病毒B19血清阳性率及其临床效果
Pub Date : 2013-04-01 DOI: 10.5251/AJSIR.2013.4.2.195.200
A. Bukar, U. Abjah, M. Kagu, A. Ladu, S. Zailani, M. Malah, B. Denue
Sickle cell anaemia (SCA) is a globally widespread genetic disorder affecting 5% of the world’s over 6 billion people. Parvovirus infection and the resulting aplastic crisis is a recognised complication in individuals with SCA. Aplastic crisis increases the need for blood transfusion and its attendant risk of Transfusion Transmissible Infection (TTI). Hence there is a vicious cycle in which Parvovirus B19 causes aplastic crisis which in turn causes increased transfusion need; and transfusion increases risk of transfusion transmissible infection in which parvovirus B19 is included in certain parts of the world. Sickle cell anaemia is associated with foetal death and infection with parvovirus B19 increases the risk to early mortality. The objective of this study was to determine the seroprevalence of parvovirus B19 among SCA and compare with that of controls in the study area. Furthermore clinical and laboratory profile of subjects were analysed to identify possible correlation with parvovirus B19 seropositivity and explore the possibility of involvement of white cell and platelets. A total of 90 subjects comprising 45 consecutive SCA case subjects and 45 age- and sex- matched non SCA controls were studied in a cross sectional comparative study. Ten millilitres of blood was drawn from the antecubital fossa of each subject after obtaining informed consent. The 10mls of blood was divided into two aliquots, 4.5 mls was added into EDTA anticoagulated bottle and was used for basic complete blood count (CBC), while the remaining 5mls was added into a plain specimen container allowed to clot and serum obtained to test for anti- parvovirus B19 IgG and IgM using an immunochromatography based technique specifically BIOCARD TM Parvo B19 diagnostic test kit. There was male preponderance in the study. The SCA subjects comprised 26 males and 19 females (male to female ratio = 1.4:1), while the non- SCA controls comprised 25 males and 20 females (male to female ratio 1.3:1).. The analysis of anti- parvovirus B19 IgG antibody revealed a prevalence of 23.3% among SCA cases with 18.9% among controls. The haematological profile is not affected by IgG seropositivity. However pregnancy outcome revealed that the total number of stillbirths is 12 among IgG seropositive SCA cases which is higher than the 6 encountered in IgG seronegative SCA subjects; the difference is statistically significant (p=0.04).
镰状细胞性贫血(SCA)是一种全球普遍存在的遗传性疾病,影响着全球60多亿人口中的5%。细小病毒感染和由此产生的再生危机是SCA患者公认的并发症。再生障碍性危机增加了输血需求和随之而来的输血传染性感染风险。因此出现了一个恶性循环,细小病毒B19引起再生危机,而再生危机又导致输血需求增加;输血增加了输血传播感染的风险,其中在世界某些地区包括细小病毒B19。镰状细胞性贫血与胎儿死亡有关,感染细小病毒B19会增加早期死亡的风险。本研究的目的是确定SCA中细小病毒B19的血清阳性率,并与研究地区的对照组进行比较。此外,还分析了受试者的临床和实验室资料,以确定与细小病毒B19血清阳性的可能相关性,并探讨白细胞和血小板参与的可能性。在一项横断面比较研究中,共有90名受试者,包括45名连续的SCA病例和45名年龄和性别匹配的非SCA对照。在征得受试者知情同意后,从每位受试者的肘前窝抽取10毫升血液。将10ml血液分成两份,其中4.5 ml加入EDTA抗凝瓶,用于基础全血细胞计数(CBC),其余5ml加入普通标本容器,允许凝血,并获得血清,使用基于免疫层析技术的特异性BIOCARD TM Parvo B19诊断试剂盒检测抗细小病毒B19 IgG和IgM。研究中男性占多数。SCA组男性26人,女性19人(男女比例为1.4:1),非SCA组男性25人,女性20人(男女比例为1.3:1)。抗细小病毒B19 IgG抗体阳性率为23.3%,对照组为18.9%。血液学特征不受IgG血清阳性的影响。但妊娠结局显示IgG血清阳性SCA患者死产总数为12例,高于IgG血清阴性SCA患者的6例;差异有统计学意义(p=0.04)。
{"title":"Seroprevalence of parvovirus B19 and its clinical effect among anaemic SCA patients in Northeastern Nigeria","authors":"A. Bukar, U. Abjah, M. Kagu, A. Ladu, S. Zailani, M. Malah, B. Denue","doi":"10.5251/AJSIR.2013.4.2.195.200","DOIUrl":"https://doi.org/10.5251/AJSIR.2013.4.2.195.200","url":null,"abstract":"Sickle cell anaemia (SCA) is a globally widespread genetic disorder affecting 5% of the world’s over 6 billion people. Parvovirus infection and the resulting aplastic crisis is a recognised complication in individuals with SCA. Aplastic crisis increases the need for blood transfusion and its attendant risk of Transfusion Transmissible Infection (TTI). Hence there is a vicious cycle in which Parvovirus B19 causes aplastic crisis which in turn causes increased transfusion need; and transfusion increases risk of transfusion transmissible infection in which parvovirus B19 is included in certain parts of the world. Sickle cell anaemia is associated with foetal death and infection with parvovirus B19 increases the risk to early mortality. The objective of this study was to determine the seroprevalence of parvovirus B19 among SCA and compare with that of controls in the study area. Furthermore clinical and laboratory profile of subjects were analysed to identify possible correlation with parvovirus B19 seropositivity and explore the possibility of involvement of white cell and platelets. A total of 90 subjects comprising 45 consecutive SCA case subjects and 45 age- and sex- matched non SCA controls were studied in a cross sectional comparative study. Ten millilitres of blood was drawn from the antecubital fossa of each subject after obtaining informed consent. The 10mls of blood was divided into two aliquots, 4.5 mls was added into EDTA anticoagulated bottle and was used for basic complete blood count (CBC), while the remaining 5mls was added into a plain specimen container allowed to clot and serum obtained to test for anti- parvovirus B19 IgG and IgM using an immunochromatography based technique specifically BIOCARD TM Parvo B19 diagnostic test kit. There was male preponderance in the study. The SCA subjects comprised 26 males and 19 females (male to female ratio = 1.4:1), while the non- SCA controls comprised 25 males and 20 females (male to female ratio 1.3:1).. The analysis of anti- parvovirus B19 IgG antibody revealed a prevalence of 23.3% among SCA cases with 18.9% among controls. The haematological profile is not affected by IgG seropositivity. However pregnancy outcome revealed that the total number of stillbirths is 12 among IgG seropositive SCA cases which is higher than the 6 encountered in IgG seronegative SCA subjects; the difference is statistically significant (p=0.04).","PeriodicalId":7661,"journal":{"name":"American Journal of Scientific and Industrial Research","volume":"56 1","pages":"195-200"},"PeriodicalIF":0.0,"publicationDate":"2013-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77874624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
One-Dimensional Velocity Model for Ife Seismic Station from Inversion of Teleseismic P-wave Travel time Data 基于远震纵波走时数据反演的Ife台站一维速度模型
Pub Date : 2013-04-01 DOI: 10.5251/AJSIR.2013.4.2.210.213
T. Yakubu, B. Dewu
A One-Dimensional inversion of P-wave travel time data observed at IFE seismic station between July 2009 when it was installed and July 2011 was carried out with the aim of obtaining the velocity model for the station region. The approach was based on fitting a series of straight lines to the travel time data. The results obtained showed that the P-wave velocity varies between 8.5 km/s and 12 km/s, which indicates that all the seismic rays’ bottom and had their turning point in the mantle. The plot of the velocity-depth profile reveals a three layer mantle with a transition at a depth of about 700 km corresponding to the transition between the upper and the lower mantle.
对2009年7月至2011年7月期间IFE地震台站观测到的纵波走时数据进行了一维反演,得到台站区域的速度模型。该方法基于对旅行时间数据拟合一系列直线。结果表明,纵波速度在8.5 km/s ~ 12 km/s之间变化,表明所有地震射线的底部都在地幔中有转折。速度-深度剖面图显示了三层地幔,在700 km左右的深度有一个过渡,对应于上下地幔之间的过渡。
{"title":"One-Dimensional Velocity Model for Ife Seismic Station from Inversion of Teleseismic P-wave Travel time Data","authors":"T. Yakubu, B. Dewu","doi":"10.5251/AJSIR.2013.4.2.210.213","DOIUrl":"https://doi.org/10.5251/AJSIR.2013.4.2.210.213","url":null,"abstract":"A One-Dimensional inversion of P-wave travel time data observed at IFE seismic station between July 2009 when it was installed and July 2011 was carried out with the aim of obtaining the velocity model for the station region. The approach was based on fitting a series of straight lines to the travel time data. The results obtained showed that the P-wave velocity varies between 8.5 km/s and 12 km/s, which indicates that all the seismic rays’ bottom and had their turning point in the mantle. The plot of the velocity-depth profile reveals a three layer mantle with a transition at a depth of about 700 km corresponding to the transition between the upper and the lower mantle.","PeriodicalId":7661,"journal":{"name":"American Journal of Scientific and Industrial Research","volume":"22 1","pages":"210-213"},"PeriodicalIF":0.0,"publicationDate":"2013-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72850531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Isolation, characterisation and anti-cholinesterase activities of Physostigma venenosum (Calabar bean) 绿豆病耻菌的分离鉴定及抗胆碱酯酶活性研究
Pub Date : 2013-04-01 DOI: 10.5251/AJSIR.2013.4.2.226.230
J. Bull, Michael Okpara
Chemical investigation of the anticholenestrases activity of the seeds of physostigma venenosum (ordeal or calabar bean, esere bean or calabar bohme) resulted in the isolation of sangainarine N-diglycoside. The structure of the compound was established using NMR spectroscopy of ( 1 H, 13 C, COSY, DEPT and HSQC) in combination with IR and MS spectral data. The seed of the plant was extracted by percolation using ethanol. The extract was partitioned to obtain chloroform, water, methanol, and pet-ether fractions. The chloroform fraction was discovered as the most active fraction in anticholinesterase activity. The compound displayed a very high anticholinesterase activity (99.5%) in an in vitro test. The result did not support the use of physostigma venenosum as an ordeal poison by the Calabar people of Nigeria to justify person accused of witch craft.
利用化学方法对青豆、卡拉巴豆和卡拉巴豆种子的抗胆甾醇酯酶活性进行了研究,分离出了桑皂苷n -二糖苷。利用核磁共振(1h, 13c, COSY, DEPT和HSQC)结合红外和质谱数据确定了化合物的结构。采用乙醇渗滤法提取植物种子。将提取液分离得到氯仿、水、甲醇和pet-醚馏分。氯仿部位是抗胆碱酯酶活性最高的部位。该化合物体外抗胆碱酯酶活性高达99.5%。这一结果并不支持尼日利亚卡拉巴尔人将毒病菌作为一种折磨人的毒药来为那些被指控使用巫术的人辩护。
{"title":"Isolation, characterisation and anti-cholinesterase activities of Physostigma venenosum (Calabar bean)","authors":"J. Bull, Michael Okpara","doi":"10.5251/AJSIR.2013.4.2.226.230","DOIUrl":"https://doi.org/10.5251/AJSIR.2013.4.2.226.230","url":null,"abstract":"Chemical investigation of the anticholenestrases activity of the seeds of physostigma venenosum (ordeal or calabar bean, esere bean or calabar bohme) resulted in the isolation of sangainarine N-diglycoside. The structure of the compound was established using NMR spectroscopy of ( 1 H, 13 C, COSY, DEPT and HSQC) in combination with IR and MS spectral data. The seed of the plant was extracted by percolation using ethanol. The extract was partitioned to obtain chloroform, water, methanol, and pet-ether fractions. The chloroform fraction was discovered as the most active fraction in anticholinesterase activity. The compound displayed a very high anticholinesterase activity (99.5%) in an in vitro test. The result did not support the use of physostigma venenosum as an ordeal poison by the Calabar people of Nigeria to justify person accused of witch craft.","PeriodicalId":7661,"journal":{"name":"American Journal of Scientific and Industrial Research","volume":"68 1","pages":"226-230"},"PeriodicalIF":0.0,"publicationDate":"2013-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86073550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation and correlation study of heavy metals load in drinking water and update of water-related disease cases in ebonyi state from 2001 – 2011 2001 - 2011年乌邦伊州饮用水重金属负荷评价与相关性研究及水相关疾病病例更新
Pub Date : 2013-04-01 DOI: 10.5251/AJSIR.2013.4.2.221.225
J. Afiukwa
Spectrophotometric and correlation analysis of heavy metal levels in drinking water was carried out. Samples from various sources of drinking water in different Local Government Areas in Ebonyi State were collected in pre-treated plastic bottles during the rainy and dry seasons and analysed for total Cd, Co, Cr, Cu, Fe, Mn, Ni, Pb and Zn. Pearson’s correlation analysis and tTest statistics were used to evaluate the relationship between elevated heavy metal ions in the sample, while Integrated Disease Surveillance and Response System (IDRS) was used in epidemiological studies to evaluate the current status of four water-related disease cases in the area between 2001 to 2011. The result showed that the prevalence of guinea worm, diarrhoea and cholera monitored dropped by a 100 %, 15.3 % and 8.6 % respectively, while typhoid fever escalated by 71.6 % in 2011 compared with the 2001 data. The result also indicated elevated metal concentrations above the WHO guideline limits for drinking water in the order; Pb > Mn > Fe > Cr > Co > Cd > Ni in surface water and Mn > Pb > Cr > Co > Fe > Cd > Ni in groundwater samples. Seasonal variations were not significant (P > 0.05). The correlation analyses showed high degree of metal association in the order: Cu/Zn > Pb/Zn > Fe/Mn > Fe/Pb > Cd/Zn > Cu/Pb > Co/Fe > Cd/Co.
对饮用水中重金属含量进行了分光光度法及相关分析。在雨季和旱季,从埃邦伊州不同地方政府地区的各种来源的饮用水中收集了样品,装在预处理的塑料瓶中,并分析了总Cd、Co、Cr、Cu、Fe、Mn、Ni、Pb和Zn。采用Pearson相关分析和tTest统计方法评价样品中重金属离子升高的关系,采用流行病学研究方法采用综合疾病监测与反应系统(IDRS)对2001 - 2011年该地区4例水相关疾病的现状进行评价。结果显示,与2001年的数据相比,2011年监测到的麦地那龙线虫、腹泻和霍乱的流行率分别下降了100%、15.3%和8.6%,而伤寒的流行率上升了71.6%。结果还表明,该地区饮用水的金属浓度高于世卫组织指导限值;地表水样品Pb > Mn > Fe > Cr > Co > Cd > Ni和地下水样品Mn > Pb > Cr > Co > Fe > Cd > Ni。季节差异不显著(P < 0.05)。相关分析表明:Cu/Zn > Pb/Zn > Fe/Mn > Fe/Pb > Cd/Zn > Cu/Pb > Co/Fe > Cd/Co。
{"title":"Evaluation and correlation study of heavy metals load in drinking water and update of water-related disease cases in ebonyi state from 2001 – 2011","authors":"J. Afiukwa","doi":"10.5251/AJSIR.2013.4.2.221.225","DOIUrl":"https://doi.org/10.5251/AJSIR.2013.4.2.221.225","url":null,"abstract":"Spectrophotometric and correlation analysis of heavy metal levels in drinking water was carried out. Samples from various sources of drinking water in different Local Government Areas in Ebonyi State were collected in pre-treated plastic bottles during the rainy and dry seasons and analysed for total Cd, Co, Cr, Cu, Fe, Mn, Ni, Pb and Zn. Pearson’s correlation analysis and tTest statistics were used to evaluate the relationship between elevated heavy metal ions in the sample, while Integrated Disease Surveillance and Response System (IDRS) was used in epidemiological studies to evaluate the current status of four water-related disease cases in the area between 2001 to 2011. The result showed that the prevalence of guinea worm, diarrhoea and cholera monitored dropped by a 100 %, 15.3 % and 8.6 % respectively, while typhoid fever escalated by 71.6 % in 2011 compared with the 2001 data. The result also indicated elevated metal concentrations above the WHO guideline limits for drinking water in the order; Pb > Mn > Fe > Cr > Co > Cd > Ni in surface water and Mn > Pb > Cr > Co > Fe > Cd > Ni in groundwater samples. Seasonal variations were not significant (P > 0.05). The correlation analyses showed high degree of metal association in the order: Cu/Zn > Pb/Zn > Fe/Mn > Fe/Pb > Cd/Zn > Cu/Pb > Co/Fe > Cd/Co.","PeriodicalId":7661,"journal":{"name":"American Journal of Scientific and Industrial Research","volume":"15 1","pages":"221-225"},"PeriodicalIF":0.0,"publicationDate":"2013-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78786947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Development of bamboo - rice husk ash and cement mixture for livestock house roofing sheets 竹稻壳灰水泥混合料的研制
Pub Date : 2013-04-01 DOI: 10.5251/AJSIR.2013.4.2.201.209
T. Omoniyi, B. Akinyemi
The purpose of this research is to design, fabricate and install locally developed roofing sheets on a king post truss model of a livestock house using rice husk and bamboo fibers which are readily available in most Nigerian farms with some additions of cement to the mixture. The effects of ratios of Rice Husk Ash (RHA) and bamboo fibers on the impact strength, density, thickness swelling and water absorption were also investigated. The average density of the composite roofing sheet produced ranged from 1779 to 2197Kg/m 3 . The control test specimen density was 2376Kg/m 3 . The addition of pozollan decreased the density of the composite. Thickness Swelling (TS) values ranged from 0.07 to 5.97% at two hours and from 0.08 to 6.5% at 24 hours for different composition. The percentage water absorption (WA) by the composite was from 0.17 to 1.13% at 2 hrs while it was 0.21 to 1.43% at 24hrs. However further research would be carried out on the structure to determine the thermal comfort of the livestock to be kept in the building.
本研究的目的是设计、制造和安装当地开发的屋面板,使用稻壳和竹纤维,这在大多数尼日利亚农场都很容易获得,并在混合物中添加一些水泥。考察了稻壳灰分与竹纤维配比对复合材料抗冲击强度、密度、厚度、膨胀率和吸水率的影响。所生产的复合屋面板的平均密度为1779 ~ 2197Kg/ m3。对照试验标本密度为2376Kg/ m3。pozollan的加入降低了复合材料的密度。不同成分的厚度膨胀(TS)值在2小时为0.07 ~ 5.97%,24小时为0.08 ~ 6.5%。2 h时复合材料的吸水率为0.17 ~ 1.13%,24h时吸水率为0.21 ~ 1.43%。然而,将对结构进行进一步的研究,以确定将在建筑物中饲养的牲畜的热舒适性。
{"title":"Development of bamboo - rice husk ash and cement mixture for livestock house roofing sheets","authors":"T. Omoniyi, B. Akinyemi","doi":"10.5251/AJSIR.2013.4.2.201.209","DOIUrl":"https://doi.org/10.5251/AJSIR.2013.4.2.201.209","url":null,"abstract":"The purpose of this research is to design, fabricate and install locally developed roofing sheets on a king post truss model of a livestock house using rice husk and bamboo fibers which are readily available in most Nigerian farms with some additions of cement to the mixture. The effects of ratios of Rice Husk Ash (RHA) and bamboo fibers on the impact strength, density, thickness swelling and water absorption were also investigated. The average density of the composite roofing sheet produced ranged from 1779 to 2197Kg/m 3 . The control test specimen density was 2376Kg/m 3 . The addition of pozollan decreased the density of the composite. Thickness Swelling (TS) values ranged from 0.07 to 5.97% at two hours and from 0.08 to 6.5% at 24 hours for different composition. The percentage water absorption (WA) by the composite was from 0.17 to 1.13% at 2 hrs while it was 0.21 to 1.43% at 24hrs. However further research would be carried out on the structure to determine the thermal comfort of the livestock to be kept in the building.","PeriodicalId":7661,"journal":{"name":"American Journal of Scientific and Industrial Research","volume":"1 1","pages":"201-209"},"PeriodicalIF":0.0,"publicationDate":"2013-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90591050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Problems of Rural Electrification in Bayelsa State 巴耶尔萨州农村电气化问题
Pub Date : 2013-04-01 DOI: 10.5251/AJSIR.2013.4.2.214.220
J. Afa
Rural electrification scheme is aimed at promoting the welfare of the rural community and improve the economic status of the people. The presence of the National Electric Power Authority (NEPA) is rarely felt, that the supply of power to Bayelsa from the grid is less than 10 percent. The Kolo creek gas turbine is only available to only two local communities in the state. The paper therefore is aimed at presenting these problems by studying the problems facing the present scheme in terms of capital cost, the dispersed settlement, the load profile and transport system. It was seen that the coastal environment and the fairly big rivers coupled with the high capital cost are major impediments to successful electrification of the state. It was seen that it cost sever time more than an equivalent scheme in the upload areas. With the abundant oil and gas resources and the renewable energies (solar and wind), off grid electrification project could be the solution to the electrification scheme if properly harnessed.
农村电气化计划旨在促进农村社区的福利,提高人民的经济地位。国家电力局(NEPA)的存在很少被感觉到,从电网到巴耶尔萨的电力供应不到10%。Kolo creek燃气轮机仅供该州两个当地社区使用。因此,本文旨在通过研究目前方案在资金成本、分散沉降、负荷分布和运输系统方面面临的问题来提出这些问题。可以看出,沿海环境和相当大的河流加上高昂的资本成本是成功电气化的主要障碍。结果表明,在上传方面,该方案比同等方案多花费了5倍的时间。中国拥有丰富的油气资源和可再生能源(太阳能和风能),如果利用得当,离网电气化项目可以成为解决电气化方案的解决方案。
{"title":"Problems of Rural Electrification in Bayelsa State","authors":"J. Afa","doi":"10.5251/AJSIR.2013.4.2.214.220","DOIUrl":"https://doi.org/10.5251/AJSIR.2013.4.2.214.220","url":null,"abstract":"Rural electrification scheme is aimed at promoting the welfare of the rural community and improve the economic status of the people. The presence of the National Electric Power Authority (NEPA) is rarely felt, that the supply of power to Bayelsa from the grid is less than 10 percent. The Kolo creek gas turbine is only available to only two local communities in the state. The paper therefore is aimed at presenting these problems by studying the problems facing the present scheme in terms of capital cost, the dispersed settlement, the load profile and transport system. It was seen that the coastal environment and the fairly big rivers coupled with the high capital cost are major impediments to successful electrification of the state. It was seen that it cost sever time more than an equivalent scheme in the upload areas. With the abundant oil and gas resources and the renewable energies (solar and wind), off grid electrification project could be the solution to the electrification scheme if properly harnessed.","PeriodicalId":7661,"journal":{"name":"American Journal of Scientific and Industrial Research","volume":"23 1","pages":"214-220"},"PeriodicalIF":0.0,"publicationDate":"2013-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90979474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Site specific measurements and propagation models for GSM in three cities in Northern Nigeria 尼日利亚北部三个城市GSM的具体地点测量和传播模型
Pub Date : 2013-04-01 DOI: 10.5251/AJSIR.2013.4.2.238.245
J. Ogbulezie, M. Onuu
{"title":"Site specific measurements and propagation models for GSM in three cities in Northern Nigeria","authors":"J. Ogbulezie, M. Onuu","doi":"10.5251/AJSIR.2013.4.2.238.245","DOIUrl":"https://doi.org/10.5251/AJSIR.2013.4.2.238.245","url":null,"abstract":"","PeriodicalId":7661,"journal":{"name":"American Journal of Scientific and Industrial Research","volume":"37 1","pages":"238-245"},"PeriodicalIF":0.0,"publicationDate":"2013-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79044079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
期刊
American Journal of Scientific and Industrial Research
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1