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November 15 Highlight. 11 月 15 日亮点
IF 19.3 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2024-11-15 DOI: 10.1164/rccm.210i10xxxii
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引用次数: 0
An Expiration Date for Etomidate? 依托咪酯的有效期?
IF 9.6 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2024-11-15 DOI: 10.1164/rccm.202409-1743ED
Michael C Sklar, Duminda N Wijeysundera
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引用次数: 0
Erratum: Digital Spatial Profiling Identifies Distinct Molecular Signatures of Vascular Lesions in Pulmonary Arterial Hypertension. 勘误:数字空间轮廓分析识别肺动脉高压血管病变的不同分子特征
IF 19.3 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2024-11-15 DOI: 10.1164/rccm.v210erratum7
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引用次数: 0
An Unfortunate Inheritance: Child Asthma in the Aftermath of Redlining. 不幸的遗产:红线之后的儿童哮喘。
IF 9.6 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2024-11-15 DOI: 10.1164/rccm.202406-1225ED
Sonali Bose, Kecia Carroll
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引用次数: 0
GZMhi Cytotoxic T Cells: A Key Discovery in Fibrotic Hypersensitivity Pneumonitis. GZMhi 细胞毒性 T 细胞:纤维化超敏性肺炎的关键发现
IF 9.6 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2024-11-15 DOI: 10.1164/rccm.202406-1194ED
Theodoros Karampitsakos, Jose D Herazo-Maya
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引用次数: 0
Validation of Systemic Complement Signatures in the Progression of Chronic Obstructive Pulmonary Disease. 验证慢性阻塞性肺病进展过程中的系统补体特征
IF 9.6 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2024-11-15 DOI: 10.1164/rccm.202311-2059LE
Katarina M DiLillo, Lisa Ruvuna, Katherine A Pratte, Karina A Serban, Wassim W Labaki, MeiLan K Han, Christine M Freeman, Russell P Bowler, Jeffrey L Curtis, Kelly B Arnold
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引用次数: 0
Virtual Peer Support for ICU Survivors Is Feasible and May Improve Outcomes for ICU Survivors: Results from the icuRESOLVE-D (icu Recovery Solutions Codesigned through Survivor Engagement - Digital) Pilot Randomized Controlled Trial. 为重症监护室幸存者提供虚拟同伴支持是可行的,并可改善重症监护室幸存者的治疗效果:icuRESOLVE-D(通过幸存者参与共同设计的重症监护室康复解决方案--数字化)试点随机对照试验的结果。
IF 9.6 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2024-11-15 DOI: 10.1164/rccm.202404-0780RL
Nina Leggett, Yasmine Ali Abdelhamid, Erin Bicknell, Sarah Booth, Jacki Carmody, Adam M Deane, K J Farley, Amalia Karahalios, Mark Merolli, Kimberley J Haines
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引用次数: 0
Vigorous Diaphragm Movement Captured by Four-Dimensional Computed Tomography in Quadriplegia Patient. 通过四维计算机断层扫描捕捉四肢瘫痪患者剧烈的膈肌运动。
IF 19.3 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2024-11-13 DOI: 10.1164/rccm.202405-0956IM
Atsuko Shono, Ken Tonai, Shinshu Katayama, Masamitsu Sanui
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引用次数: 0
World Pneumonia Day 2024: Fighting Pneumonia and Antimicrobial Resistance. 2024 年世界肺炎日:抗击肺炎和抗菌药耐药性。
IF 19.3 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2024-11-12 DOI: 10.1164/rccm.202408-1540ED
Catia Cilloniz, Charles S Dela Cruz, Guinevere Dy-Agra, Rodolfo S Pagcatipunan
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引用次数: 0
Interventional Strategies for Children with Progressive Pulmonary Hypertension Despite Optimal Therapy. An Official American Thoracic Society Clinical Practice Guideline. 儿童在接受最佳治疗后仍出现进展性肺动脉高压的介入治疗策略。美国胸科学会官方临床实践指南。
IF 19.3 1区 医学 Q1 CRITICAL CARE MEDICINE Pub Date : 2024-11-12 DOI: 10.1164/rccm.202410-1901ST
Don Hayes, Ann L Jennerich, Ryan D Coleman, Eric Abston, Gregory T Adamson, John T Berger, Sarah P Cohen, David S Cooper, Pirooz Eghtesady, Francis Fynn-Thompson, R Mark Grady, Stephanie M Hon, Charles W Hoopes, Teresa Jewell, Hayley Lewthwaite, Michelle F Liu, David C McGiffin, Mary P Mullen, Athar M Qureshi, David L S Morales

Background: Pulmonary hypertension in children often progresses despite optimal therapy. This document provides an evidence-based clinical practice guideline for the management of children with progressive pulmonary hypertension despite optimal therapy.

Methods: A multidisciplinary panel identified pertinent questions regarding the management of children with pulmonary hypertension that has progressed despite optimal therapy, conducted systematic reviews of the relevant literature, and applied the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach to develop clinical recommendations.

Results: After reviewing the research evidence, the panel considered the balance of desirable (benefits) and undesirable (harms and burdens) effects of the interventions in each proposed question. Valuation of our main outcomes was also considered, along with resources required, equity, acceptability, and feasibility. Recommendations were developed for or against interventional strategies specific to children with pulmonary hypertension that has progressed despite optimal therapy.

Conclusions: Although there is a growing population of children with pulmonary hypertension, there is a striking lack of empirical evidence regarding management of those whose disease has progressed despite optimal pharmacotherapy. The panel formulated and provided the rationale for clinical recommendations for or against interventional strategies based on this limited empirical evidence, coupled with expert opinion, to aid clinicians in the management of these complex pediatric patients. In addition, we identified important areas for future research.

背景:尽管采用了最佳治疗方法,儿童肺动脉高压仍经常会进展。本文件提供了一份以证据为基础的临床实践指南,用于治疗虽经最佳治疗但病情仍在进展的肺动脉高压患儿:方法:一个多学科专家小组确定了在接受最佳治疗后仍有进展的肺动脉高压患儿管理方面的相关问题,对相关文献进行了系统回顾,并采用建议、评估、发展和评价分级法(GRADE)制定了临床建议:在对研究证据进行审查后,专家小组考虑了每个建议问题中干预措施的理想效果(益处)和不理想效果(危害和负担)之间的平衡。同时还考虑了主要结果的价值以及所需资源、公平性、可接受性和可行性。针对尽管接受了最佳治疗但病情仍有进展的肺动脉高压患儿,我们提出了支持或反对干预策略的建议:尽管肺动脉高压患儿的数量在不断增加,但对于那些在接受了最佳药物治疗后病情仍在发展的患儿,其治疗方法却明显缺乏经验证据。专家组根据这些有限的经验证据,结合专家意见,制定了支持或反对干预策略的临床建议,并提供了相关理由,以帮助临床医生管理这些复杂的儿科患者。此外,我们还确定了未来研究的重要领域。
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引用次数: 0
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American journal of respiratory and critical care medicine
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