Pub Date : 2025-01-02DOI: 10.1164/rccm.202410-2008VP
Amy Heinzerling, Robert Harrison, Jennifer Flattery, Jane C Fazio, Sheiphali Gandhi, Kristin J Cummings
{"title":"Deadly Countertops: An Urgent Need to Eliminate Silicosis among Engineered Stone Workers.","authors":"Amy Heinzerling, Robert Harrison, Jennifer Flattery, Jane C Fazio, Sheiphali Gandhi, Kristin J Cummings","doi":"10.1164/rccm.202410-2008VP","DOIUrl":"https://doi.org/10.1164/rccm.202410-2008VP","url":null,"abstract":"","PeriodicalId":7664,"journal":{"name":"American journal of respiratory and critical care medicine","volume":" ","pages":""},"PeriodicalIF":19.3,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142920540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-02DOI: 10.1164/rccm.202404-0861RL
Paolo Persona, Ilaria Valeri, Francesco Zarantonello, Edoardo Forin, Emanuele Pivetta, Tommaso Antonio Giacon, Tommaso Pettenuzzo, Giovanni Volpicelli, Paolo Navalesi
{"title":"Lung Ultrasound to Detect Overdistension in Mechanically Ventilated Patients: A Pilot Study.","authors":"Paolo Persona, Ilaria Valeri, Francesco Zarantonello, Edoardo Forin, Emanuele Pivetta, Tommaso Antonio Giacon, Tommaso Pettenuzzo, Giovanni Volpicelli, Paolo Navalesi","doi":"10.1164/rccm.202404-0861RL","DOIUrl":"https://doi.org/10.1164/rccm.202404-0861RL","url":null,"abstract":"","PeriodicalId":7664,"journal":{"name":"American journal of respiratory and critical care medicine","volume":" ","pages":""},"PeriodicalIF":19.3,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142920470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-23DOI: 10.1164/rccm.202405-0921OC
Fernando J Martinez, Barbara P Yawn, Daniela Angulo, Camden Lopez, Susan Murray, David Mannino, Stacey Anderson, Rowena Dolor, Nancy Elder, Min Joo, Irfan Khan, Lyndee M Knox, Catherine Meldrum, Elizabeth Peters, Cathie Spino, Hazel Tapp, Byron Thomashow, Linda Zittleman, Randall Brown, Barry Make, MeiLan K Han
Rationale: The impact of COPD screening on US primary care clinician behavior and patient outcomes is unclear. Objectives: Assess the impact of receiving CAPTURE (COPD Assessment in Primary Care to Identify Undiagnosed Respiratory Disease and Exacerbation Risk) screening scores on clinical and patient outcomes. Methods: Cluster randomized trial included 49 usual care (COPD education only) and 51 intervention (COPD and CAPTURE education plus screening scores) primary care practices. Twelve-month medical record and patient survey outcome data were collected in patients with elevated screening scores or study spirometric abnormalities. Measurements and Main Results: Among 387 CAPTURE+ patients, no significant difference was noted between usual care and intervention practices in the primary composite outcome of: 1) spirometry referral/completion, 2) new COPD diagnosis, 3) newly prescribed inhaled long-acting respiratory medication, 4) referral to a respiratory specialist, or 5) pulmonary rehabilitation referral/completion, 45.9% versus 41.9% (+4.0%, 95% CI -6.9, +15.0, p=0.47). Only spirometry referral/completion was higher in the intervention group (+10.4%, 95% CI +0.1, +20.7, p = 0.0465). No differences were noted for secondary outcomes, composite components, change in COPD Assessment Test scores, rates of respiratory illnesses, or hospitalizations. For the 1,028 screen-negative (CAPTURE-) patients, composite primary and all secondary outcomes were similar in the two arms. In secondary and post hoc analyses evaluating the potential impact of the pandemic, intervention group differences in clinician and patient outcomes were noted for CAPTURE+ and CAPTURE- patients in the pre-pandemic period that diminished during the pandemic. Conclusions: Within these US primary care practices, COPD and CAPTURE education plus receipt of CAPTURE screening scores did not change clinician COPD assessment or care or patient outcomes for CAPTURE+ patients. However, in the pre-pandemic period CAPTURE+ patients were more likely to undergo spirometry referral completion while for CAPTURE- patients clinicians were significantly less likely to assess for COPD suggesting that the intervention resulted in a more appropriate use of healthcare resources.
{"title":"Impact of the CAPTURE COPD Screening Tool in US Primary Care: A Cluster Randomized Trial.","authors":"Fernando J Martinez, Barbara P Yawn, Daniela Angulo, Camden Lopez, Susan Murray, David Mannino, Stacey Anderson, Rowena Dolor, Nancy Elder, Min Joo, Irfan Khan, Lyndee M Knox, Catherine Meldrum, Elizabeth Peters, Cathie Spino, Hazel Tapp, Byron Thomashow, Linda Zittleman, Randall Brown, Barry Make, MeiLan K Han","doi":"10.1164/rccm.202405-0921OC","DOIUrl":"https://doi.org/10.1164/rccm.202405-0921OC","url":null,"abstract":"<p><p><i>Rationale:</i> The impact of COPD screening on US primary care clinician behavior and patient outcomes is unclear. <i>Objectives:</i> Assess the impact of receiving CAPTURE (COPD Assessment in Primary Care to Identify Undiagnosed Respiratory Disease and Exacerbation Risk) screening scores on clinical and patient outcomes. <i>Methods:</i> Cluster randomized trial included 49 usual care (COPD education only) and 51 intervention (COPD and CAPTURE education plus screening scores) primary care practices. Twelve-month medical record and patient survey outcome data were collected in patients with elevated screening scores or study spirometric abnormalities. <i>Measurements and Main Results:</i> Among 387 CAPTURE+ patients, no significant difference was noted between usual care and intervention practices in the primary composite outcome of: 1) spirometry referral/completion, 2) new COPD diagnosis, 3) newly prescribed inhaled long-acting respiratory medication, 4) referral to a respiratory specialist, or 5) pulmonary rehabilitation referral/completion, 45.9% versus 41.9% (+4.0%, 95% CI -6.9, +15.0, p=0.47). Only spirometry referral/completion was higher in the intervention group (+10.4%, 95% CI +0.1, +20.7, p = 0.0465). No differences were noted for secondary outcomes, composite components, change in COPD Assessment Test scores, rates of respiratory illnesses, or hospitalizations. For the 1,028 screen-negative (CAPTURE-) patients, composite primary and all secondary outcomes were similar in the two arms. In secondary and post hoc analyses evaluating the potential impact of the pandemic, intervention group differences in clinician and patient outcomes were noted for CAPTURE+ and CAPTURE- patients in the pre-pandemic period that diminished during the pandemic. <i>Conclusions:</i> Within these US primary care practices, COPD and CAPTURE education plus receipt of CAPTURE screening scores did not change clinician COPD assessment or care or patient outcomes for CAPTURE+ patients. However, in the pre-pandemic period CAPTURE+ patients were more likely to undergo spirometry referral completion while for CAPTURE- patients clinicians were significantly less likely to assess for COPD suggesting that the intervention resulted in a more appropriate use of healthcare resources.</p>","PeriodicalId":7664,"journal":{"name":"American journal of respiratory and critical care medicine","volume":" ","pages":""},"PeriodicalIF":19.3,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142880646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-19DOI: 10.1164/rccm.202411-2117ED
Emerson M Wickwire, Amy M Sawyer
{"title":"Leveraging Peer-driven Social Support to Improve Care Delivery and Outcomes in Obstructive Sleep Apnea.","authors":"Emerson M Wickwire, Amy M Sawyer","doi":"10.1164/rccm.202411-2117ED","DOIUrl":"https://doi.org/10.1164/rccm.202411-2117ED","url":null,"abstract":"","PeriodicalId":7664,"journal":{"name":"American journal of respiratory and critical care medicine","volume":" ","pages":""},"PeriodicalIF":19.3,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142862895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-19DOI: 10.1164/rccm.202403-0526RL
Joseph R Fontana, Joel Moss, Dong-Yun Kim, Mario Stylianou, Stewart J Levine, Amisha V Barochia, Nargues Weir, Les R Folio, Huy Michael Do, Vincent Manganiello
{"title":"Atorvastatin in Severity-stratified Pulmonary Sarcoidosis: A Phase II Randomized Controlled Trial.","authors":"Joseph R Fontana, Joel Moss, Dong-Yun Kim, Mario Stylianou, Stewart J Levine, Amisha V Barochia, Nargues Weir, Les R Folio, Huy Michael Do, Vincent Manganiello","doi":"10.1164/rccm.202403-0526RL","DOIUrl":"https://doi.org/10.1164/rccm.202403-0526RL","url":null,"abstract":"","PeriodicalId":7664,"journal":{"name":"American journal of respiratory and critical care medicine","volume":" ","pages":""},"PeriodicalIF":19.3,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142862742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-19DOI: 10.1164/rccm.202408-1642VP
Leo Heunks, Dirk W Donker, Eline Oppersma, Coen A C Ottenheijm, Jonne Doorduin
{"title":"Diaphragm Pacing in Early Critical Illness? A Plea for a Super-relaxed Approach.","authors":"Leo Heunks, Dirk W Donker, Eline Oppersma, Coen A C Ottenheijm, Jonne Doorduin","doi":"10.1164/rccm.202408-1642VP","DOIUrl":"https://doi.org/10.1164/rccm.202408-1642VP","url":null,"abstract":"","PeriodicalId":7664,"journal":{"name":"American journal of respiratory and critical care medicine","volume":" ","pages":""},"PeriodicalIF":19.3,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142862743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-19DOI: 10.1164/rccm.202411-2119LE
Claudia Crimi, Annalisa Carlucci
{"title":"Timing for Initiating Home Noninvasive Ventilation in Italy: Beyond Clinical Parameters.","authors":"Claudia Crimi, Annalisa Carlucci","doi":"10.1164/rccm.202411-2119LE","DOIUrl":"https://doi.org/10.1164/rccm.202411-2119LE","url":null,"abstract":"","PeriodicalId":7664,"journal":{"name":"American journal of respiratory and critical care medicine","volume":" ","pages":""},"PeriodicalIF":19.3,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142862900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-19DOI: 10.1164/rccm.202406-1197RL
Felipe Kazmirczak, Ryan Moon, Neal T Vogel, Walt Tollison, Matt T Lahti, John P Carney, Jenna B Mendelson, Todd Markowski, LeeAnn Higgins, Kevin Murray, Candace Guerrero, Kurt W Prins
{"title":"Ferroptosis Inhibition Combats Metabolic Derangements and Improves Cardiac Function in Pulmonary Artery Banded Pigs.","authors":"Felipe Kazmirczak, Ryan Moon, Neal T Vogel, Walt Tollison, Matt T Lahti, John P Carney, Jenna B Mendelson, Todd Markowski, LeeAnn Higgins, Kevin Murray, Candace Guerrero, Kurt W Prins","doi":"10.1164/rccm.202406-1197RL","DOIUrl":"10.1164/rccm.202406-1197RL","url":null,"abstract":"","PeriodicalId":7664,"journal":{"name":"American journal of respiratory and critical care medicine","volume":" ","pages":""},"PeriodicalIF":19.3,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142862762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-19DOI: 10.1164/rccm.202411-2199ED
Arnaud W Thille, Sylvain Le Pape
{"title":"Prophylactic Noninvasive Ventilation after Extubation of Obese Patients.","authors":"Arnaud W Thille, Sylvain Le Pape","doi":"10.1164/rccm.202411-2199ED","DOIUrl":"https://doi.org/10.1164/rccm.202411-2199ED","url":null,"abstract":"","PeriodicalId":7664,"journal":{"name":"American journal of respiratory and critical care medicine","volume":" ","pages":""},"PeriodicalIF":19.3,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142862898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-19DOI: 10.1164/rccm.202411-2290ED
Karl J Staples
{"title":"In Asthma, Change Is the Only Constant.","authors":"Karl J Staples","doi":"10.1164/rccm.202411-2290ED","DOIUrl":"https://doi.org/10.1164/rccm.202411-2290ED","url":null,"abstract":"","PeriodicalId":7664,"journal":{"name":"American journal of respiratory and critical care medicine","volume":" ","pages":""},"PeriodicalIF":19.3,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142862773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}