Pub Date : 2024-11-15DOI: 10.1164/rccm.210i10xxxii
{"title":"November 15 Highlight.","authors":"","doi":"10.1164/rccm.210i10xxxii","DOIUrl":"https://doi.org/10.1164/rccm.210i10xxxii","url":null,"abstract":"","PeriodicalId":7664,"journal":{"name":"American journal of respiratory and critical care medicine","volume":"210 10","pages":"xxxii-xxxiv"},"PeriodicalIF":19.3,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142638548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-15DOI: 10.1164/rccm.202409-1743ED
Michael C Sklar, Duminda N Wijeysundera
{"title":"An Expiration Date for Etomidate?","authors":"Michael C Sklar, Duminda N Wijeysundera","doi":"10.1164/rccm.202409-1743ED","DOIUrl":"10.1164/rccm.202409-1743ED","url":null,"abstract":"","PeriodicalId":7664,"journal":{"name":"American journal of respiratory and critical care medicine","volume":" ","pages":"1178-1180"},"PeriodicalIF":9.6,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11568430/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142405834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-15DOI: 10.1164/rccm.v210erratum7
{"title":"Erratum: Digital Spatial Profiling Identifies Distinct Molecular Signatures of Vascular Lesions in Pulmonary Arterial Hypertension.","authors":"","doi":"10.1164/rccm.v210erratum7","DOIUrl":"10.1164/rccm.v210erratum7","url":null,"abstract":"","PeriodicalId":7664,"journal":{"name":"American journal of respiratory and critical care medicine","volume":"210 10","pages":"1279-1280"},"PeriodicalIF":19.3,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11568431/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142638546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-15DOI: 10.1164/rccm.202406-1225ED
Sonali Bose, Kecia Carroll
{"title":"An Unfortunate Inheritance: Child Asthma in the Aftermath of Redlining.","authors":"Sonali Bose, Kecia Carroll","doi":"10.1164/rccm.202406-1225ED","DOIUrl":"10.1164/rccm.202406-1225ED","url":null,"abstract":"","PeriodicalId":7664,"journal":{"name":"American journal of respiratory and critical care medicine","volume":" ","pages":"1171-1173"},"PeriodicalIF":9.6,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11568445/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141791664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-15DOI: 10.1164/rccm.202406-1194ED
Theodoros Karampitsakos, Jose D Herazo-Maya
{"title":"GZM<sup>hi</sup> Cytotoxic T Cells: A Key Discovery in Fibrotic Hypersensitivity Pneumonitis.","authors":"Theodoros Karampitsakos, Jose D Herazo-Maya","doi":"10.1164/rccm.202406-1194ED","DOIUrl":"10.1164/rccm.202406-1194ED","url":null,"abstract":"","PeriodicalId":7664,"journal":{"name":"American journal of respiratory and critical care medicine","volume":" ","pages":"1180-1182"},"PeriodicalIF":9.6,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11568438/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141791685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-15DOI: 10.1164/rccm.202311-2059LE
Katarina M DiLillo, Lisa Ruvuna, Katherine A Pratte, Karina A Serban, Wassim W Labaki, MeiLan K Han, Christine M Freeman, Russell P Bowler, Jeffrey L Curtis, Kelly B Arnold
{"title":"Validation of Systemic Complement Signatures in the Progression of Chronic Obstructive Pulmonary Disease.","authors":"Katarina M DiLillo, Lisa Ruvuna, Katherine A Pratte, Karina A Serban, Wassim W Labaki, MeiLan K Han, Christine M Freeman, Russell P Bowler, Jeffrey L Curtis, Kelly B Arnold","doi":"10.1164/rccm.202311-2059LE","DOIUrl":"10.1164/rccm.202311-2059LE","url":null,"abstract":"","PeriodicalId":7664,"journal":{"name":"American journal of respiratory and critical care medicine","volume":" ","pages":"1269-1272"},"PeriodicalIF":9.6,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11568447/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-15DOI: 10.1164/rccm.202404-0780RL
Nina Leggett, Yasmine Ali Abdelhamid, Erin Bicknell, Sarah Booth, Jacki Carmody, Adam M Deane, K J Farley, Amalia Karahalios, Mark Merolli, Kimberley J Haines
{"title":"Virtual Peer Support for ICU Survivors Is Feasible and May Improve Outcomes for ICU Survivors: Results from the icuRESOLVE-D (icu Recovery Solutions Codesigned through Survivor Engagement - Digital) Pilot Randomized Controlled Trial.","authors":"Nina Leggett, Yasmine Ali Abdelhamid, Erin Bicknell, Sarah Booth, Jacki Carmody, Adam M Deane, K J Farley, Amalia Karahalios, Mark Merolli, Kimberley J Haines","doi":"10.1164/rccm.202404-0780RL","DOIUrl":"10.1164/rccm.202404-0780RL","url":null,"abstract":"","PeriodicalId":7664,"journal":{"name":"American journal of respiratory and critical care medicine","volume":" ","pages":"1273-1276"},"PeriodicalIF":9.6,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-13DOI: 10.1164/rccm.202405-0956IM
Atsuko Shono, Ken Tonai, Shinshu Katayama, Masamitsu Sanui
{"title":"Vigorous Diaphragm Movement Captured by Four-Dimensional Computed Tomography in Quadriplegia Patient.","authors":"Atsuko Shono, Ken Tonai, Shinshu Katayama, Masamitsu Sanui","doi":"10.1164/rccm.202405-0956IM","DOIUrl":"https://doi.org/10.1164/rccm.202405-0956IM","url":null,"abstract":"","PeriodicalId":7664,"journal":{"name":"American journal of respiratory and critical care medicine","volume":" ","pages":""},"PeriodicalIF":19.3,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142612433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-12DOI: 10.1164/rccm.202408-1540ED
Catia Cilloniz, Charles S Dela Cruz, Guinevere Dy-Agra, Rodolfo S Pagcatipunan
{"title":"World Pneumonia Day 2024: Fighting Pneumonia and Antimicrobial Resistance.","authors":"Catia Cilloniz, Charles S Dela Cruz, Guinevere Dy-Agra, Rodolfo S Pagcatipunan","doi":"10.1164/rccm.202408-1540ED","DOIUrl":"https://doi.org/10.1164/rccm.202408-1540ED","url":null,"abstract":"","PeriodicalId":7664,"journal":{"name":"American journal of respiratory and critical care medicine","volume":" ","pages":""},"PeriodicalIF":19.3,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142612438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-12DOI: 10.1164/rccm.202410-1901ST
Don Hayes, Ann L Jennerich, Ryan D Coleman, Eric Abston, Gregory T Adamson, John T Berger, Sarah P Cohen, David S Cooper, Pirooz Eghtesady, Francis Fynn-Thompson, R Mark Grady, Stephanie M Hon, Charles W Hoopes, Teresa Jewell, Hayley Lewthwaite, Michelle F Liu, David C McGiffin, Mary P Mullen, Athar M Qureshi, David L S Morales
Background: Pulmonary hypertension in children often progresses despite optimal therapy. This document provides an evidence-based clinical practice guideline for the management of children with progressive pulmonary hypertension despite optimal therapy.
Methods: A multidisciplinary panel identified pertinent questions regarding the management of children with pulmonary hypertension that has progressed despite optimal therapy, conducted systematic reviews of the relevant literature, and applied the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach to develop clinical recommendations.
Results: After reviewing the research evidence, the panel considered the balance of desirable (benefits) and undesirable (harms and burdens) effects of the interventions in each proposed question. Valuation of our main outcomes was also considered, along with resources required, equity, acceptability, and feasibility. Recommendations were developed for or against interventional strategies specific to children with pulmonary hypertension that has progressed despite optimal therapy.
Conclusions: Although there is a growing population of children with pulmonary hypertension, there is a striking lack of empirical evidence regarding management of those whose disease has progressed despite optimal pharmacotherapy. The panel formulated and provided the rationale for clinical recommendations for or against interventional strategies based on this limited empirical evidence, coupled with expert opinion, to aid clinicians in the management of these complex pediatric patients. In addition, we identified important areas for future research.
{"title":"Interventional Strategies for Children with Progressive Pulmonary Hypertension Despite Optimal Therapy. An Official American Thoracic Society Clinical Practice Guideline.","authors":"Don Hayes, Ann L Jennerich, Ryan D Coleman, Eric Abston, Gregory T Adamson, John T Berger, Sarah P Cohen, David S Cooper, Pirooz Eghtesady, Francis Fynn-Thompson, R Mark Grady, Stephanie M Hon, Charles W Hoopes, Teresa Jewell, Hayley Lewthwaite, Michelle F Liu, David C McGiffin, Mary P Mullen, Athar M Qureshi, David L S Morales","doi":"10.1164/rccm.202410-1901ST","DOIUrl":"https://doi.org/10.1164/rccm.202410-1901ST","url":null,"abstract":"<p><strong>Background: </strong>Pulmonary hypertension in children often progresses despite optimal therapy. This document provides an evidence-based clinical practice guideline for the management of children with progressive pulmonary hypertension despite optimal therapy.</p><p><strong>Methods: </strong>A multidisciplinary panel identified pertinent questions regarding the management of children with pulmonary hypertension that has progressed despite optimal therapy, conducted systematic reviews of the relevant literature, and applied the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach to develop clinical recommendations.</p><p><strong>Results: </strong>After reviewing the research evidence, the panel considered the balance of desirable (benefits) and undesirable (harms and burdens) effects of the interventions in each proposed question. Valuation of our main outcomes was also considered, along with resources required, equity, acceptability, and feasibility. Recommendations were developed for or against interventional strategies specific to children with pulmonary hypertension that has progressed despite optimal therapy.</p><p><strong>Conclusions: </strong>Although there is a growing population of children with pulmonary hypertension, there is a striking lack of empirical evidence regarding management of those whose disease has progressed despite optimal pharmacotherapy. The panel formulated and provided the rationale for clinical recommendations for or against interventional strategies based on this limited empirical evidence, coupled with expert opinion, to aid clinicians in the management of these complex pediatric patients. In addition, we identified important areas for future research.</p>","PeriodicalId":7664,"journal":{"name":"American journal of respiratory and critical care medicine","volume":" ","pages":""},"PeriodicalIF":19.3,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142612383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}