Anais brasileiros de dermatologia最新文献

The month of January 1925 marks the birth of the Annaes Brasileiros de Dermatologia e Syphilografia and currently, 100 years later, with great merit, we celebrate its evolution into Anais Brasileiros de Dermatologia (ABD). Indeed, those few brilliant pioneers never dreamed of the strength of the Brazilian Society of Dermatology nowadays. However, perhaps they envisioned a relevant role for ABD, with a natural space for dermatoses of infectious etiology, always prevalent in tropical and subtropical regions. And thus, it was established for decades. Currently, Brazilian Dermatology and ABD are plural and open to the different facets of Dermatology. However, both the specialty, Dermatology, and its official body, ABD, value and pay homage to history, and cannot forget or stray from it. Numerous challenges have been faced over the past 100 years. Many other challenges still remain, but it is up to us, as a gift to the 100^th anniversary of the Anais Brasileiros de Dermatologia, to learn about them and reflect on them. The following text provides a summary of the history of ABD over the years. We invite national and international readers to celebrate with us.

Background: Prurigo nodularis is a chronic pruritic dermatosis and narrowband-UVB (NB-UVB) phototherapy is considered an effective and safe treatment option in patients with multiple comorbidities.

Objective: In this study, the authors aimed to evaluate the efficacy and safety of NB-UVB phototherapy in the management of prurigo nodularis and to compare response rates according to lesions localization.

Methods: Thirty prurigo nodularis patients who had been treated with NB-UVB phototherapy were included in this study. The data for this study were retrieved retrospectively from patient follow-up forms in the phototherapy unit.

Results: NB-UVB phototherapy led to a complete response (CR) in 24 (80%) patients while partial response (PR) was achieved in 6 (20%) patients. Regarding prurigo nodularis localization, the CR rate was statistically higher in those with diffuse and central involvement (p < 0.05). Erythema and/or pruritus were observed in 4 (13.3%) patients with prurigo nodularis.

Study limitations: This study is limited because it is single-centered and has a retrospective design.

Conclusions: NB-UVB phototherapy is an effective and safe treatment option for prurigo nodularis patients especially those with multiple comorbidities and using several medications. Patients with diffuse and central involvement may respond better to phototherapy than those with peripheral involvement.

Background: Childhood and adolescence are the most active periods for nevi development, which provide insights into nevogenesis.

Objectives: To evaluate the clinical and dermoscopic characteristics of acquired melanocytic nevi in Turkish children (aged ≤ 10-years) and adolescents (aged > 10-years) regarding demographic, constitutional, and environmental factors.

Methods: A cross-sectional study on participants aged < 18-years examined for acquired melanocytic nevi between January and June 2023.

Results: One hundred participants (female: male ratio = 1:1; median age: 10) were assessed. The median nevi number was significantly higher in adolescents than in children (6 vs. 4; p < 0.05). The upper extremities (n = 68) and trunk (n = 67) were the most commonly involved anatomical regions. Females had a significantly higher nevi rate on the upper extremities than males (80% vs. 56%; p < 0.05). The trunk was involved slightly more frequently in males (76% vs. 58%; p = 0.06). The globular pattern rate was higher in children than in adolescents (70.6% vs. 42.9%; p < 0.05), whereas a striking increase was observed in the reticular pattern from childhood (2%) to adolescence (14.3%) (p < 0.05). The globular pattern was the major dermoscopic pattern in all anatomical locations except lower extremities where the homogeneous pattern prevailed. Sunscreen use had no impact on the nevi number or dermoscopic pattern.

Study limitations: Limited number of participants.

Conclusions: The age and anatomical site were the most relevant factors influencing the number and dermoscopic patterns of nevi. The gender-related distribution pattern of nevi, without any effect of sunscreen use on either nevus count or dermoscopic pattern, suggests a genetic predisposition.