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Total financial and avoidable losses due to lameness in Turkish dairy herds 土耳其奶牛群跛足造成的经济损失和可避免的损失
4区 农林科学 Q3 VETERINARY SCIENCES Pub Date : 2023-08-01 DOI: 10.33988/auvfd.1214635
Savaş SARIÖZKAN, Mehmet KÜÇÜKOFLAZ
This study aimed to estimate the total financial (direct and indirect) and avoidable losses related to lameness in Turkish dairy herds. Official and previous published data were used for determining the mean (12.9%) and target prevalence (6.6%) values. Direct financial losses due to lameness were calculated as treatment costs, involuntary culling, and milk yield losses. Indirect losses consisted of extended calving intervals and extra insemination losses. As a result, an average financial losses of lameness per case on dairy farms was $153.8 ($116.8 for mild and $264.7 for severe forms). Avoidable losses were calculated ($75.1), equalling 187 Lt. of cow milk in Türkiye conditions. The share of direct and indirect financial losses was 49.6% and 50.4%, respectively. Total annual losses related to lameness in Türkiye are calculated as $130.5 million (326 million Lt. milk eq.); however, $63.7 million (=159 million Lt. milk eq.) of the losses could be avoided by farmers. Milk equivalent of avoidable losses equates to 0.77% of the total milk production of Türkiye annually. In conclusion, lameness causes significant financial losses in Turkish dairy herds. However, almost half of these losses (48.8%) may be avoidable with a better management practices, thus increasing the productivity and profitability of dairy farmers.
本研究旨在估计与土耳其奶牛群跛足有关的总财务(直接和间接)和可避免的损失。使用官方和以前发表的数据来确定平均值(12.9%)和目标患病率(6.6%)值。跛足造成的直接经济损失计算为治疗费用、非自愿扑杀和产奶量损失。间接损失包括产犊间隔延长和额外的授精损失。因此,奶牛养殖场每例跛行造成的平均经济损失为153.8美元(轻度跛行116.8美元,重度跛行264.7美元)。计算出可避免的损失(75.1美元),相当于在 rkiye条件下187升牛奶。直接和间接经济损失的比例分别为49.6%和50.4%。基耶州每年与跛足有关的总损失计算为1.305亿美元(3.26亿牛奶当量);然而,农民可以避免6370万美元(= 1.59亿牛奶当量)的损失。可避免损失的牛奶当量相当于每年 rkiye牛奶总产量的0.77%。总之,跛行给土耳其奶牛群造成了重大的经济损失。然而,这些损失的近一半(48.8%)可以通过更好的管理实践来避免,从而提高奶农的生产力和盈利能力。
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引用次数: 0
Superficial pyoderma in cats and dogs: A retrospective clinical study 猫和狗的浅表性脓皮病:回顾性临床研究
IF 0.7 4区 农林科学 Q3 VETERINARY SCIENCES Pub Date : 2023-06-13 DOI: 10.33988/auvfd.1239626
Nevra Keskin Yılmaz, B. Baş
Superficial pyoderma is a common complication of a range of feline and canine skin diseases. The objective of the present study is to retrospectively evaluate bacterial and fungal skin culture samples in superficial pyoderma cases of cats and dogs and to reveal in detail the pathogens and their susceptibility and/or resistance to antimicrobials, as well as demographic data and clinical symptoms of the patients. Medical records of 28 cats and 35 dogs meeting the criteria for inclusion were reviewed. Staphylococcus spp. and Trichophyton species were found to be the most common cultured microorganisms in both cats and dogs. Antimicrobial resistance was determined both in cat and dog samples. As a result, it has been demonstrated that skin culture is particularly important for the management of diagnosis and treatment processes and the regulation of treatment protocols in pyoderma in terms of preventing the increasing antibiotic resistance in recent years and thus protecting both human and animal health.
浅表性脓皮病是一系列猫和犬皮肤病的常见并发症。本研究的目的是回顾性评估猫和狗的浅表脓皮病病例的细菌和真菌皮肤培养样本,并详细揭示病原体及其对抗菌素的敏感性和/或耐药性,以及患者的人口统计数据和临床症状。审查了符合纳入标准的28只猫和35只狗的医疗记录。葡萄球菌和毛癣菌是猫和狗中最常见的培养微生物。在猫和狗样本中均测定了抗菌素耐药性。因此,已经证明,皮肤培养对于脓皮病的诊断和治疗过程的管理以及治疗方案的调节特别重要,以防止近年来不断增加的抗生素耐药性,从而保护人类和动物的健康。
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引用次数: 0
Effective Use of Plastinated Specimens For Hybrid Learning of Veterinary Anatomy 动物解剖混合学习中塑化标本的有效利用
4区 农林科学 Q3 VETERINARY SCIENCES Pub Date : 2023-06-13 DOI: 10.33988/auvfd.1142921
Okan EKİM, Caner BAKICI, Barış BATUR, Selçuk TUNALI
With the official announcement of the new type of coronavirus-induced COVID-19 outbreak as a global pandemic, a special situation that no one has ever encountered has started. Developments that are expected to happen in next decade in many fields have been completed in the last 3 years. One of these fields was undoubtedly education. Hybrid learning is a trending educational approach that combines face-to-face and online learning. The aim of this article is to give ideas and make suggestions about how plastinates, which have been used efficiently in anatomy practices and professional training, can be used in hybrid learning of veterinary anatomy. Plastinated specimens come to the forefront for hybrid education with various advantageous features. They are not only non-toxic, dry, odorless materials, but plastinates also can simulate the natural anatomic appearance in a detailed manner. With the help of new-generation acrylic paints and dyes which can penetrate into tissues, plastinates offer a unique natural look rather impressive than any other techniques. Due to the features mentioned above, plastinates are also convenient materials for handling, transportation or storage. These specified properties were discussed in terms of the compatibility to hybrid learning procedures in this article.
随着新型冠状病毒引发的新冠肺炎疫情正式宣布为全球大流行,前所未有的特殊局面开始了。在过去的三年里,许多领域预计在未来十年发生的发展已经完成。其中一个领域无疑是教育。混合学习是一种结合了面对面和在线学习的趋势教育方法。在解剖学实践和专业培训中已得到有效应用的塑化材料如何应用于兽医解剖学的混合学习,本文的目的是提出一些想法和建议。塑化标本以其多种优势成为混合教育的前沿。它们不仅是无毒,干燥,无味的材料,而且塑化物还可以详细地模拟自然解剖外观。在新一代丙烯酸颜料和染料的帮助下,可以渗透到组织中,塑化提供了一种独特的自然外观,比任何其他技术都令人印象深刻。由于上述特点,塑化塑料也是便于搬运、运输或储存的材料。本文从混合学习过程的兼容性角度讨论了这些特定的属性。
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引用次数: 0
Spinal Meningothelial Meningioma In a Dog 犬脊髓脊膜上皮性脑膜瘤
4区 农林科学 Q3 VETERINARY SCIENCES Pub Date : 2023-06-08 DOI: 10.33988/auvfd.1170085
Ilayda PAZARBASİLAR, Oya Burçin DEMİRTAŞ, Nur Beyza NAZIR, Sevil ATALAY VURAL, Ömer BEŞALTI
The objective of this study is to report clinical, MRI, surgical and histological findings of spinal meningothelial meningioma in a dog. Study material was a 9 years old, spayed dog with history of progressive non ambulatory tetra paresis. The dog had intact cranial and spinal reflexes, and deep pain perception. Magnetic resonance images revealed a mass located at left side C2-C3 level, hyperintense in T1W, isointense on T2W, well contrast enhancing on postcontrast T1. The mass was microsurgically resected sub gross totally. The dog’s neurological status was improved at one week and survived for 15 months without signs of metastasis. Histological and histochemical workup revealed grade I, meningothelial meningioma. Surgical intervention for spinal meningioma can be suggested as a sole treatment in dogs.
本研究的目的是报告犬脊膜上皮脑膜瘤的临床、MRI、手术和组织学表现。研究对象是一只患有进行性非活动性四肢麻痹病史的9岁绝育犬。狗有完整的颅骨和脊柱反射,和深度疼痛感知。磁共振显示肿块位于左侧C2-C3水平,T1W呈高信号,T2W呈等信号,T1增强。经显微外科手术切除肿块。狗的神经系统状况在一周后得到改善,并存活了15个月,没有转移的迹象。组织学和组织化学检查显示为一级脑膜上皮性脑膜瘤。手术干预脊髓脑膜瘤可以建议作为唯一的治疗犬。
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引用次数: 0
Views of Veterinary Faculty Students on the Concept of Artificial Intelligence and Its Use in Veterinary Medicine Practices: An Example of XXXX University Faculty of Veterinary Medicine 兽医学院学生对人工智能概念及其在兽医实践中的应用的看法——以XXXX大学兽医学院为例
IF 0.7 4区 农林科学 Q3 VETERINARY SCIENCES Pub Date : 2023-06-06 DOI: 10.33988/auvfd.1221352
N. Yerlikaya, Ö. Küçükaslan
Artificial intelligence is a developing concept in the field of veterinary medicine, as in other health fields. The study was carried out to determine the knowledge levels of the students of Ankara University Faculty of Veterinary Medicine, which is the most established veterinary faculty in Türkiye, on the concept of artificial intelligence and its use in veterinary practices. For this purpose, an online questionnaire was applied to a total of 529 students who wanted to participate in the study, covering all grades of the faculty. The questionnaire consists of two parts. In the first part, there are 10 questions including demographics, level of computer use, knowledge about the concept of artificial intelligence, etc. The second part consists of 26 5-point Likert-type questions to determine students' thoughts on artificial intelligence applications. Data were analyzed using statistical tests. Consequently, the students participating in the study are partially knowledgeable about artificial intelligence (52.9%). They know the importance of following the developments in artificial intelligence for the profession (45.2%). They think that artificial intelligence applications will improve their professional skills (53.5%). They have the opinion that a robot cannot replace a veterinary surgeon (36.7%) and artificial intelligence cannot cause unemployment in veterinary medicine in the future (35.3%). In addition, they believe that artificial intelligence can cause ethical problems (39.3%) and that applications made with this technology should be developed in an ethical sense (42.4%). As a result, while the students think that artificial intelligence will have positive effects in the field of veterinary medicine, they also think that artificial intelligence can bring negative ethical implications. It can be concluded that including elective courses on artificial intelligence applications in veterinary faculties and conducting further research on the subject would be beneficial.
与其他卫生领域一样,人工智能在兽医领域也是一个发展中的概念。开展这项研究是为了确定安卡拉大学兽医学院(土耳其最成熟的兽医学院)学生对人工智能概念及其在兽医实践中的应用的知识水平。为此,我们对529名希望参与研究的学生进行了在线问卷调查,涵盖了学院的所有年级。问卷由两部分组成。在第一部分中,有10个问题,包括人口统计,计算机使用水平,关于人工智能概念的知识等。第二部分由26道李克特式5分题组成,以确定学生对人工智能应用的看法。采用统计检验对数据进行分析。因此,参与研究的学生对人工智能有部分了解(52.9%)。他们知道关注人工智能的发展对职业的重要性(45.2%)。他们认为人工智能应用将提高他们的专业技能(53.5%)。他们认为机器人无法取代兽医(36.7%),人工智能未来不会导致兽医失业(35.3%)。此外,他们认为人工智能可能会引发伦理问题(39.3%),并认为利用这项技术开发的应用应该在伦理意义上进行开发(42.4%)。因此,学生们在认为人工智能将对兽医领域产生积极影响的同时,也认为人工智能会带来负面的伦理影响。可以得出结论,在兽医学院开设人工智能应用选修课并开展进一步的研究将是有益的。
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引用次数: 0
Investigation of Serum Anti-Mullerian Hormone Levels at Follicular Phase and Interestrus Period in Queens 皇后区卵泡期和发情期血清抗苗勒管激素水平的调查
IF 0.7 4区 农林科学 Q3 VETERINARY SCIENCES Pub Date : 2023-05-29 DOI: 10.33988/auvfd.1222284
İlknur Pi̇ryağci, Gökberk Seven, Taha Burak Elifoglu, İ. Polat, M. Pekcan
The objectives of this study were to report mean serum AMH concentrations in adult queens, to determine relationship between AMH concentrationss with estradiol level, to investigate the relationship between serum AMH with follicular phase and interestrus period and to discuss the usability of AMH as a biomarker to diagnosis of ovarian remnant syndrome. In the study, 64 adult and healthy female queen, who were brought to clinics for ovariohysterectomy were used. After anamnesis, vaginal cytology, macroscopic examination of the uterus and ovaries and estradiol measurement, queens were divided into two groups: follicular phase (n: 45) and interestrus (n: 19). Estradiol and AMH levels in serum samples were determined by ELISA. In the evaluation of serum AMH concentrations, a statistical difference was determined between the follicular phase and interestrus (p˂0.05). A negative correlation was found between age and estradiol in both follicular phase (r = -0.171) and interestrus (r = -0.385) groups. A positive correlation was found between age and AMH in the interestrus (p˂0.01, r = 0.696). Serum AMH levels in the interestrus were found to be significantly higher than follicular phase (p˂0.05). It was thought that this increase in serum AMH levels during the interestrus period, which is the stage where oocytes were selected for ovulation, may be an indicator of the role of AMH in oocyte selection in queens, as in many other mammalian species.
本研究的目的是报告成年蜂王的平均血清AMH浓度,确定AMH浓度与雌二醇水平的关系,探讨血清AMH与卵泡期和发情期的关系,并讨论AMH作为卵巢残留综合征的生物标志物的可用性。在这项研究中,64名成年健康的雌性皇后被带到诊所进行卵巢子宫切除术。经记忆、阴道细胞学检查、子宫卵巢宏观检查和雌二醇测定后,将皇后分为卵泡期(45例)和发情期(19例)两组。ELISA法测定血清中雌二醇和AMH水平。在评估血清AMH浓度时,确定卵泡期和发情期之间有统计学差异(p小于0.05)。在卵泡期(r = -0.171)和发情期(r = -0.385)组,年龄与雌二醇均呈负相关。年龄与卵巢AMH呈正相关(p小于0.01,r = 0.696)。卵巢期血清AMH水平明显高于卵泡期(p小于0.05)。人们认为,在卵母细胞被选择排卵的发情期,血清AMH水平的增加可能是AMH在蜂王中卵母细胞选择中的作用的一个指标,就像在许多其他哺乳动物物种中一样。
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引用次数: 0
Histochemical and Immunohistochemical Investigations on Pyloric Tonsil in Turkeys (Meleagris gallopavo) 火鸡幽门扁桃体的组织化学和免疫组织化学研究
IF 0.7 4区 农林科学 Q3 VETERINARY SCIENCES Pub Date : 2023-05-12 DOI: 10.33988/auvfd.1242236
Nuh Yıldırım
Structural patterns of pyloric tonsil in turkeys (Meleagris gallopavo) were investigated in this study. Turkeys, less resistant to disease than chickens, are a crucial source of protein with low cholesterol levels and a high protein/calorie ratio. Pyloric tonsil, involved in the chicken defense barrier, is a component of GALT. To evaluate the specific region, adult turkeys were taken from slaughterhouses. Crossman's modified triple staining demonstrated the general histological structure, PAS revealed the density of goblet cells synthesizing mucus, and Safranin O showed the capsule around the follicles. The width of lymphoid follicles in the pyloric tonsil (204.0±22.33) differed significantly from that of the middle part of the duodenum (111.7±4.741). It was noticed that the specific area harbors T cells, B cells, and follicular dendritic cells. Interfollicular regions were infiltrated with CD3+T cells, but the CD268+B cells occupied primarily germinal centers. However, it was noticed that T cells were present in germinal centers and some B cells in the interfollicular region. Anti-Vimentin antibody revealed follicular dendritic cells in the pyloric zone. It was noted that the epithelial layer of the pyloric tonsil is devoid of CK18-positive cells. Findings of the semi-thin section indicated that some columnar epithelial cells were stained differently in the transition zone (lymphoepithelium). To sum up, a pyloric region in turkeys is structurally dissimilar to pyloric tonsils detected in chicken, chukar partridge, and duck. More research is needed to reveal the effect of pyloric tonsil on the alimentary tract in poultry in terms of defense mechanisms.
本研究对火鸡幽门扁桃体的结构模式进行了研究。火鸡对疾病的抵抗力不如鸡,是胆固醇水平低、蛋白质/热量比例高的蛋白质的重要来源。幽门扁桃体参与鸡的防御屏障,是GALT的一个组成部分。为了评估特定地区,从屠宰场采集成年火鸡。克罗斯曼改良三重染色显示了一般的组织学结构,PAS显示了合成粘液的杯状细胞的密度,番红O显示了卵泡周围的包膜。幽门扁桃体的淋巴滤泡宽度(204.0±22.33)与十二指肠中部的淋巴滤泡宽(111.7±4.741)有显著差异。CD3+T细胞浸润卵泡间区域,但CD268+B细胞主要占据生发中心。然而,我们注意到T细胞存在于生发中心,一些B细胞存在于滤泡间区域。抗波形蛋白抗体显示幽门区有滤泡树突状细胞。值得注意的是,幽门扁桃体的上皮层没有CK18阳性细胞。半薄切片的结果表明,一些柱状上皮细胞在过渡区(淋巴上皮)染色不同。总之,火鸡的幽门区域在结构上与鸡、丘卡鹧鸪和鸭的幽门扁桃体不同。需要更多的研究来揭示幽门扁桃体在防御机制方面对家禽消化道的影响。
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引用次数: 0
First dose optimization study on freezing Anatolian buffalo semen 安纳托利亚水牛精液冷冻首次剂量优化研究
IF 0.7 4区 农林科学 Q3 VETERINARY SCIENCES Pub Date : 2023-05-04 DOI: 10.33988/auvfd.1205794
I. Bastan, D. Şahi̇n, Fırat Korkmaz, Seher Simsek, U. Kaya, M. Satilmis
The main objective of sperm production centers is to produce as many straws as possible from the obtained ejaculates using the optimal dilution rate. To this end, this study is the first to evaluate the effect of different semen extender rates on Anatolian buffalo semen quality. Ejaculates were collected by artificial vagina from three Anatolian buffalo bulls (n=105). These ejaculates were divided into three aliquots and filled into 0.25 ml straws with soy-based extenders at the concentrations of 35, 25, and 15 million spermatozoa/straw. The straw samples of different spermatozoa concentrations were frozen. The quality of spermatozoa was evaluated after thawing (37 °C, 30 sec) and following the thermoresistance test (37 °C, 3 h). The post-thaw total motility and progressive motility values were similar between the groups. However, following the thermoresistance test, there was a significant decrease in total motility in the 35 million spermatozoa/straw group, and the progressive motility was significantly higher in the 25 million spermatozoa/straw group. There was no statistically significant difference between the groups in terms of sperm kinetic parameters, except VSL after thawing except the VAP and LIN values following the thermoresistance test. In conclusion, it is recommended to dilute the Anatolian buffalo semen at a concentration of 25 or 100 million spermatozoa/ml per straw when freezing it with a soy-based semen extender. In addition, it is considered that soy-based extenders compensate for cryo-damage to sperm motility for a short time, and the thermoresistance test should be applied for objective evaluation in dose optimization studies.
精子生产中心的主要目标是使用最佳稀释率从获得的射精中生产尽可能多的吸管。为此,本研究首次评价了不同增精率对安纳托利亚水牛精液质量的影响。用人工阴道收集了3头安纳托利亚水牛的射精(n=105)。这些射精被分成三等分,分别以35、25和1500万个精子/吸管的浓度用大豆为基础的扩展剂填充到0.25 ml的吸管中。将不同精子浓度的吸管样品冷冻。在解冻(37°C, 30秒)和耐热性测试(37°C, 3小时)后评估精子的质量。解冻后两组精子的总运动性和渐进运动性值相似。然而,经过耐热性测试,3500万精子/吸管组的总运动性显著降低,2500万精子/吸管组的进行性运动性显著升高。除解冻后的VSL外,各组间除热阻试验后的VAP和LIN值外,其他精子动力学参数差异均无统计学意义。综上所述,建议在冷冻安纳托利亚水牛精液时,用大豆基精液扩增剂稀释浓度为每根吸管25或1亿个精子/ml。此外,认为大豆基扩展剂可在短时间内补偿精子活力受到的低温损伤,在剂量优化研究中应采用耐热性试验进行客观评价。
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引用次数: 0
Head and neck tumors detected in dogs and cats between 2011-2021: a retrospective study 2011-2021年间在狗和猫身上发现的头颈部肿瘤:一项回顾性研究
IF 0.7 4区 农林科学 Q3 VETERINARY SCIENCES Pub Date : 2023-04-12 DOI: 10.33988/auvfd.1197926
Gözde YÜCEL TENEKECİ, Oya Burçin Demi̇rtaş, Osman Kutsal, S. ATALAY VURAL
The aim of this study is to determine and compare the distribution, localization, race, age and gender incidences of head and neck region tumors by years by evaluating the results of canine-cat biopsy and/or operation material brought to Ankara University Faculty of Veterinary Pathology Department between 2011-2021. In the study, 244 (15.9%) of 1533 tumors diagnosed in dogs and cats between 2011-2021 belonged to the head and neck region, of which 159 were in dogs and 85 in cats. Dogs with tumors were more than 6 years old (n=108) and cats were 1 year and older (n=75). In the head and neck region observed in dogs, malignant and benign tumors of epithelial origin were most common (n: 81; 50.9%), and sebaceous tumors (n: 22) were the most common epithelial tumors. Among the tumors of this region, epithelial tumors are mostly encountered in cats (n: 39; 45.8%), and 51.2% of the epithelial tumors are squamous cell cancer (n: 20), epithelial tumors are most common in the mouth (n: 12) and nose (n: 12). n:9) was observed.
本研究的目的是通过评估2011-2021年期间送到安卡拉大学兽医病理学学院的犬猫活检和/或手术材料的结果,确定和比较头颈部肿瘤的分布、定位、种族、年龄和性别发病率。在这项研究中,2011年至2021年期间在狗和猫身上诊断出的1533个肿瘤中,有244个(15.9%)属于头颈部区域,其中159个在狗身上,85个在猫身上。患肿瘤的狗大于6岁(n=108),猫大于1岁(n=75)。在犬的头颈部,上皮性的恶性和良性肿瘤最为常见(n: 81;50.9%),皮脂腺肿瘤(22例)是最常见的上皮性肿瘤。在该区域的肿瘤中,上皮性肿瘤多见于猫(n: 39;45.8%), 51.2%的上皮性肿瘤为鳞状细胞癌(n: 20),上皮性肿瘤最常见于口腔(n: 12)和鼻腔(n: 12)。N:9)。
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引用次数: 0
A comparison of anesthesia induction by two different administration routes and doses of ketamine and medetomidine in red-eared sliders (Trachemys scripta elegans) 氯胺酮与美托咪定两种给药途径及剂量对红耳滑梯麻醉诱导的比较
IF 0.7 4区 农林科学 Q3 VETERINARY SCIENCES Pub Date : 2023-03-09 DOI: 10.33988/auvfd.1145264
Ismar Lutvikadić, A. Maksimović
This study aimed to assess the efficiency of ketamine and medetomidine by two different doses and routes on anesthesia depth and cardiac stability in red-eared sliders. Each turtle was anesthetized two times, with seven days wash-out period. Induction of anesthesia consisted of a bolus combination of ketamine (10 mg/kg) and medetomidine (0.2 mg/kg) administered in the left brachial biceps in the intramuscular protocol, or a bolus combination of ketamine (20 mg/kg) and medetomidine (0.2 mg/kg) administered in subcarapacial sinus after clear blood presence confirmation in the intravenous protocol. Vital signs, reaction on the skin palpation, manual mouth opening for endotracheal intubation, palpebral and cloacal reflex, and the withdrawal reflex of the front and hind limbs were measured and recorded every 5 minutes for 60 minutes after anesthesia injection. Atipamezole (1 mg/kg) was administered in the right brachial biceps one hour after ketamine and medetomidine administration. Needle insertion and possible painful reactions to drug administration were also evaluated and recorded. Obtained data were analyzed for normality and paired t-tests, Wilcoxon, or McNamar tests were performed where appropriate. The values of P ≤ 0.05 were considered significant. A significantly less pronounced decrease in heart rate was observed with intravenous anesthesia protocol. Both protocols recorded complete anesthesia recovery 60 minutes after intramuscular atipamezole administration. A ketamine-medetomidine dose combination administered intravenously provides a more stable and consistent anesthetic plane in red-eared sliders than ketamine-medetomidine administered intramuscularly.
本研究旨在评价氯胺酮和美托咪定两种不同剂量和途径对红耳滑梯麻醉深度和心脏稳定性的影响。每只龟麻醉2次,洗脱期7天。诱导麻醉包括在肌肉注射方案中,在左肱二头肌中给予氯胺酮(10mg /kg)和美托咪定(0.2 mg/kg)的联合用药,或在静脉注射方案中,在明确血液存在后,在甲壳下窦中给予氯胺酮(20mg /kg)和美托咪定(0.2 mg/kg)的联合用药。注射麻醉后60分钟,每隔5分钟测量一次生命体征、皮肤触诊反应、气管插管手开口、眼睑和肛管反射、前肢和后肢退缩反射。氯胺酮和美托咪定给药1小时后,右肱二头肌给予阿替帕唑(1mg /kg)。同时,还对患者进行了针刺和可能出现的给药疼痛反应的评估和记录。对获得的数据进行正态性分析,并在适当情况下进行配对t检验、Wilcoxon检验或McNamar检验。P≤0.05为显著性。在静脉麻醉方案中观察到的心率下降明显不那么明显。两种方案均记录了肌注阿替帕唑后60分钟的完全麻醉恢复情况。与肌注氯胺酮-美托咪定相比,静脉给药氯胺酮-美托咪定联合给药在红耳滑鼠中提供了更稳定和一致的麻醉平面。
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Ankara Universitesi Veteriner Fakultesi Dergisi
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