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Ontogeny of responsiveness to gonadotrophins and prostaglandin E in the neonatal rat ovary 新生大鼠卵巢对促性腺激素和前列腺素E反应的个体发生
Pub Date : 1979-01-01 DOI: 10.1051/RND:19790819
S. Lamprecht, B. Funkenstein, A. Nimrod
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引用次数: 3
A. Recherches anatomopathologiques chez le rat ingérant différentes doses d'huile d'arachide ou d'huile de colza à faible teneur en acide érucique (Huile de colza Primor). 6b. Etude structurale et ultrastructurale du myocarde A.大鼠摄入不同剂量花生油或低芥酸菜籽油(菜籽油)的解剖病理学研究。6b。心肌的结构和超微结构研究
Pub Date : 1979-01-01 DOI: 10.1051/RND:19790409
A. Bodak, J. M. Dutrieux, M. Moravec, H. Guillemot, P. Hatt
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引用次数: 1
Patterns of gene activity during ovum formation in the mouse 小鼠卵子形成过程中的基因活动模式
Pub Date : 1979-01-01 DOI: 10.1051/RND:19790902
G. Moore, S. Lintern-moore
We have examined the transcriptional activities of the mouse oocyte genome during follicle growth in order to obtain information on the stages at which the synthesis of particular RNA species becomes important. The effects of gonadotrophins on these patterns of transcription have also been investigated. RNA synthesis in oocytes was measured at different stages of growth using a cytochemical application of the standard biochemical assay for DNA-dependent RNA polymerase. The presence of endogenous nucleolar and nucleoplasmic polymerases was detected by autoradiography and their relative activities were quantitated by grain counts. Both activities were relatively low in oocytes of the resting pool of small follicles but increased as growth commenced, reaching a peak as the oocytes approached maximum size. Thereafter RNA polymerase activities declined rapidly and were very low in the oocytes of large, antral follicles. Administration of PMSG to mice had no significant effect on the polymerases of oocytes of small follicles or during the early stages of follicles growth when compared with saline-treated controls. However, in oocytes which had attained maximum size, a statistically significant increase in nucleolar labelling was detected after PMSG treatment. The elevated levels of RNA polymerase activity were confined to oocytes within this growth compartment. These observations are discussed in relation to the way the production of gene transcripts is regulated during the growth of the oocyte, both with respect to the storage of informational molecules and the development of meiotic maturation competence.
我们研究了小鼠卵母细胞基因组在卵泡生长过程中的转录活性,以获得特定RNA物种合成变得重要的阶段的信息。促性腺激素对这些转录模式的影响也被研究过。在卵母细胞的不同生长阶段,使用细胞化学应用标准的dna依赖性RNA聚合酶的生化分析来测量RNA合成。用放射自显影法检测内源性核仁和核质聚合酶的存在,用粒数测定它们的相对活性。这两种活性在小卵泡静止池的卵母细胞中相对较低,但随着生长开始增加,在卵母细胞接近最大尺寸时达到峰值。此后,RNA聚合酶活性迅速下降,并且在大的卵泡卵母细胞中非常低。与盐水处理的对照组相比,PMSG对小鼠小卵泡卵母细胞的聚合酶和卵泡生长的早期阶段没有显著影响。然而,在达到最大尺寸的卵母细胞中,经PMSG处理后,核仁标记量有统计学意义的增加。RNA聚合酶活性的升高仅限于该生长室内的卵母细胞。这些观察结果讨论了在卵母细胞生长过程中基因转录物的产生是如何被调节的,既涉及到信息分子的储存,也涉及到减数分裂成熟能力的发展。
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引用次数: 5
Influence d'une élévation de température sur l'évolution de l'aminoacidémie et de l'ammoniémie après le repas chez la truite arc en ciel (Salmo gairdneri R.) 温度升高对虹鳟鱼餐后氨基酸中毒和氨血症发展的影响(Salmo gairdneri R.)
Pub Date : 1979-01-01 DOI: 10.1051/RND:19790708
B. Fauconneau, P. Luquet
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引用次数: 12
The initiation of oocyte growth in the mouse ovary 卵母细胞在小鼠卵巢内开始生长
Pub Date : 1979-01-01 DOI: 10.1051/RND:19790901
S. Lintern-moore, G. Moore
HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignement et de recherche français ou étrangers, des laboratoires publics ou privés. The initiation of oocyte growth in the mouse ovary Sue Lintern-Moore, G. P. M. Moore
它是一个多学科的开放获取档案,用于科学研究文件的存储和传播,无论它们是否出版。这些文件可能来自法国或国外的教学和研究机构,也可能来自公共或私人研究中心。HAL开放多学科档案旨在存放和传播来自法国或外国教育和研究机构、公共或私人实验室的已发表或未发表的研究级科学文件。= =地理= =根据美国人口普查,这个县的面积为。
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引用次数: 12
A. Recherches anatomopathologiques chez le rat ingérant différentes doses d'huile d'arachide ou d'huile de colza à faible teneur en acide érucique (Huile de colza Primor). 4. Etude anatomique générale du myocarde A.大鼠摄入不同剂量花生油或低芥酸菜籽油(菜籽油)的解剖病理学研究。4. 心肌的一般解剖研究
Pub Date : 1979-01-01 DOI: 10.1051/RND:19790405
O. Schmitt, T. Degas, M. Langlois, P. Pérot
Summary. A. Anatomo-pathological research on rats ingesting different doses of peanut oil or of low-erucic acid rapeseed oil (Primor rapeseed oil). 4. General ariatomy of the myocardium. The general anatomy of the myocardium (histiocytic infiltrations, fibrosis, loose connec- tive tissue, white spots) was studied on 4 rats from each lot. No dose or oil-effect was found. The length of the diet generally tended to influence the development of lesions.
总结。A.大鼠摄入不同剂量花生油或低芥酸菜籽油(初级菜籽油)的解剖病理研究。4. 心肌的一般性变异。每组4只大鼠进行心肌解剖观察(组织细胞浸润、纤维化、结缔组织疏松、白斑)。未发现剂量效应或油效应。饮食的长度通常倾向于影响病变的发展。
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引用次数: 0
Early effects of undernutrition on the development of cerebellar Bergmann glia cells 营养不良对小脑伯格曼神经胶质细胞发育的早期影响
Pub Date : 1979-01-01 DOI: 10.1051/RND:19790204
J. Clos, C. Legrand, J. Legrand
The morphological maturation of Bergmann glia cells, which might play a particularly important role in the histogenesis of the cerebellar cortex, was studied in GolgiCox preparations and electron micrographs of the cerebellum of normal and undernourished young rats. An unexpected acceleration in the morphological development of Bergmann glia cells was observed in the undernourished animals during the early postnatal period.
研究了正常和营养不良幼鼠小脑GolgiCox制剂和电子显微图中伯格曼神经胶质细胞的形态成熟,伯格曼神经胶质细胞在小脑皮层的组织发生中可能起着特别重要的作用。在出生后早期营养不良的动物中,伯格曼神经胶质细胞的形态发育出现了意想不到的加速。
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引用次数: 5
Effet d'une interruption et de restitutions partielles du recyclage entéro-hépatique sur le niveau de l'excrétion biliaire chez le porc 肠肝循环中断和部分恢复对猪胆汁排泄水平的影响
Pub Date : 1979-01-01 DOI: 10.1051/RND:19790309
Catherine Juste, T. Corring, Georgette Fredou, A. Roger, A. V. Hecke
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引用次数: 3
Effets de la malnutrition protéinocalorique et de la réalimentation équilibrée sur les activités lipasique et phospholipasique A2 du pancréas et du suc pancréatique de rat 蛋白质热营养不良和均衡再喂养对大鼠胰腺和胰液脂质和磷脂A2活性的影响
Pub Date : 1979-01-01 DOI: 10.1051/RND:19790623
J. Prost, Mahmoud-Nazih Bouziane, J. Belleville
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引用次数: 0
Influence du niveau des apports énergétiques pendant la fin de la gestation sur l'insulinémie et l'aminoacidémie des brebis et de leurs agneaux 妊娠末期能量摄入水平对母羊和羔羊胰岛素血症和氨基酸血症的影响
Pub Date : 1979-01-01 DOI: 10.1051/RND:19790207
J. Grizard, P. Patureau-Mirand, M. Tissier, O. Bernard, G. Bayle, A. Brelurut, J. Leroux
This 2 x 2 factorial experiment (table 1) was carried out in the autumn on 22 Limousine ewes during pregnancy and lactation. The animals bore or were suckling twins. The experimental treatments included 2 levels of energy intake during 7 weeks prepartum (high : H ; low : B) and 2 states of body reserves at 8 weeks prepartum (fat : G ; lean : M). Jugular blood samples were taken from ewes at 34, 20 and 6 days prepartum, and from lambs at lambing and at 6 hrs., 24 hrs., 12 days and 24 days after lambing. Blood glucose, urea and free amino acids and plasma insulin were recorded. Reducing dietary energy supply did not change lamb birth weight in autumn (fig. 1 A). It contrasted with a large diminution in the spring (Grizard et al., 1979a, b). There was a decrease of glucose and of some non-essential free amino acids (alanine, glutamate, proline, citrulline) in the blood of the ewes. Most of the non-essential free amino acids decreased during the first day of life in the blood of lambs (fig. 2A). Reducing body reserves resulted in an increase of glucose and glutamine but in a decrease of some other free amino acids (glutamate, ornithine, histidine) in the blood of ewes (fig. 1 B). It increased daily weight gain during the first 3 weeks of life in lambs (fig. 2B). At the beginning of life, plasma insulin in lambs seemed to be related to birthweight and to blood glucose in the mothers.
这项2 × 2因子试验(表1)于秋季对22只妊娠和哺乳期的利姆塞纳母羊进行。这些动物生了或正在吃奶的双胞胎。试验处理包括准备7周2个能量摄入水平(高:H;低:B)和2种状态的身体储备在8周前(脂肪:G;在母羊准备的第34天、第20天和第6天,以及羔羊在产羔和第6小时采集颈静脉血样。24小时。产羔后12天和24天。记录血糖、尿素、游离氨基酸和血浆胰岛素。减少饲粮能量供应并没有改变秋季羔羊的出生体重(图1a)。与之形成鲜明对比的是,春季羔羊的出生体重会大幅下降(griard等人,1979a, b)。母羊血液中的葡萄糖和一些非必需的游离氨基酸(丙氨酸、谷氨酸、脯氨酸、瓜氨酸)会下降。羔羊血液中的大多数非必需游离氨基酸在出生第一天就减少了(图2A)。机体储备的减少导致母羊血液中葡萄糖和谷氨酰胺的增加,但其他一些游离氨基酸(谷氨酸、鸟氨酸、组氨酸)的减少(图1b)。在羔羊出生后的前3周内,它增加了每日体重增加(图2B)。在生命之初,羔羊的血浆胰岛素似乎与出生体重和母亲的血糖有关。
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引用次数: 2
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Annales De Biologie Animale Biochimie Biophysique
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