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Erratum au résumé : « Intérêt du dépistage précoce de la maladie de Fabry » [Ann Cardiol Angeiol (Paris) 2024 ; 73/5 (2024), 101828] 摘要Erratum:《法布里病早期检测的意义》[Ann Cardiol Angeiol(巴黎)2024年;73/5(2024年),101828年]
IF 0.3 Q4 Medicine Pub Date : 2025-05-06 DOI: 10.1016/j.ancard.2025.101897
S. Aroua , M. Boukheloua
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引用次数: 0
Accessibilité au TAVI dans un centre dépourvu de chirurgie cardiaque : Un exemple Corse 在没有心脏手术的中心获得TAVI:科西嘉岛的一个例子
IF 0.3 Q4 Medicine Pub Date : 2025-05-06 DOI: 10.1016/j.ancard.2025.101898
F. Ferrandi , F. Collart , A. Cribier , H. Eltchaninoff , P. Luporsi
<div><h3>Introduction</h3><div>La sténose aortique est la valvulopathie la plus fréquente en France. Sa prévalence augmente avec l'âge, touchant plus de 10 % des personnes de plus de 70 ans. Une fois symptomatique, le pronostic est sombre, avec un taux de mortalité proche de 50 % dans les 2 ans. Les recommandations européennes pour la prise en charge des sténoses aortiques sévères recommandent une prise en charge rapide dès l'apparition des symptômes. Cependant, la sténose aortique reste largement sous-diagnostiquée et sous-traitée, notamment avec un accès aux soins limité et de plus en plus complexe en raison de la géographie. L'objectif principal de ce travail est d'analyser la prise en charge de tous les patients atteints de sténose aortique sévère symptomatique adressés au CHU de Bastia de janvier 2019 à décembre 2022. L'objectif secondaire est d'étudier les facteurs qui retardent la prise en charge et d'évaluer les conséquences sur l'évolution de ces patients.</div></div><div><h3>Matériels et méthodes</h3><div>Les données de 151 patients diagnostiqués avec une sténose aortique sévère symptomatique entre le 1er janvier 2019 et le 31 décembre 2022 au CHU de Bastia ont été recueillies rétrospectivement.</div></div><div><h3>Résultats</h3><div>Notre population était composée à 69 % d'hommes, d'âge moyen de 80 ans. Le risque opératoire était faible, avec un Euroscore moyen de 5 (Euroscore 0-45). La grande majorité des patients étaient symptomatiques, avec une dyspnée d'effort NYHA >2 (76 %). La FEVG moyenne était de 55 %, ce qui signifie que la plupart des patients avaient une fraction d'éjection ventriculaire gauche préservée. Une donnée significative que nous avons recueillie était le délai d'attente avant l'intervention. Parmi les patients inclus (102), le délai entre le diagnostic et l'implantation du TAVI était en moyenne de 162 jours (plus de 5 mois). Le délai entre la coronarographie et l'implantation du TAVI était d'environ 109 jours, contre une moyenne nationale de 70 jours. Parmi les patients inclus, 13 % sont décédés en attente et 7 % ont refusé le traitement proposé. L’étude des délais de bilan préopératoire n’a pas identifié de délai d’examen particulier comme cause principale, mais nous pouvons conclure que le processus global contribue à ces résultats.</div></div><div><h3>Conclusion</h3><div>Cette étude révèle qu’un quart des patients atteints de sténose aortique sévère dans cette population ne peuvent actuellement pas bénéficier d’un remplacement valvulaire percutané. Une prise en charge sur place, sans recours à la chirurgie cardiaque, pourrait être envisagée pour réduire les délais d’attente et la mortalité, comme cela se fait ailleurs en Europe.</div></div><div><h3>Introduction</h3><div>Aortic stenosis is the most common valvular disease in France. Its prevalence increases with age, affecting more than 10 % of people over 70 years old. Once symptomatic, the prognosis is grim, with a mortality rate close to 50 % within 2 years
主动脉狭窄是法国最常见的瓣膜疾病。其发病率随年龄增长而影响10%以上,70多岁的人。一旦有症状,预后很暗,有接近50%的死亡率在2岁。欧洲的建议来接管推荐快速治疗血管主动脉严厉,一旦出现症状。然而,主动脉狭窄在很大程度上仍未得到充分诊断和外包,特别是由于地理位置的原因,获得治疗的机会有限,而且越来越复杂。这项工作的主要目的是分析2019年1月至2022年12月期间在巴斯夏医院收治的所有症状严重主动脉狭窄患者的管理情况。第二目的是研究延迟治疗的因素,并评估对这些患者的发展的影响。材料和方法回顾性收集了2019年1月1日至2022年12月31日期间在巴斯夏CHU诊断为症状严重主动脉狭窄的151名患者的数据。结果:我们的人口由69%的男性组成,平均年龄80岁,手术风险低,欧洲评分平均为5(欧洲评分0-45)。绝大多数患者都有症状,有NYHA运动障碍2(76%)。平均FEVG为55%,这意味着大多数患者保留了部分左心室喷射。我们收集的一个重要数据是手术前的等待时间。在纳入患者(102例)中,从诊断到TAVI植入的平均时间为162天(超过5个月)。冠状动脉造影和TAVI植入之间的时间约为109天,而全国平均时间为70天。在这些患者中,13%的人在等待期间死亡,7%的人拒绝接受治疗。对术前检查时间的研究并没有确定特定的检查时间是主要原因,但我们可以得出结论,整个过程有助于这些结果。结论:这项研究表明,在这一人群中,四分之一的严重主动脉狭窄患者目前无法从经皮瓣膜置换中受益。可以考虑在不进行心脏手术的情况下进行现场护理,以减少等待时间和死亡率,就像欧洲其他地方所做的那样。主动脉狭窄是英国最常见的瓣膜疾病。它的患病率随着年龄的增长而增加,影响70岁以上人群的10%以上。一旦出现症状,预后严峻,2年内死亡率接近50%。欧洲严重主动脉狭窄管理指南建议在症状开始时迅速治疗。然而,主动脉狭窄在很大程度上仍未得到充分诊断和治疗,特别是由于地理原因,获得护理的机会有限和日益复杂。本研究的主要目的是分析2019年1月至2022年12月期间转诊到巴斯夏医院的所有症状严重主动脉狭窄患者的管理。第二目标是研究延迟治疗的因素,并评估对这些患者结果的后果。回顾性收集了2019年1月1日至2022年12月31日期间在巴斯蒂亚医院诊断为症状严重主动脉狭窄的151名患者的材料和方法数据。我们的人口由69%的男性组成,平均年龄为80岁。运营风险较低,欧洲评分平均为5分(欧洲评分0-45分)。绝大多数患者是有症状的,有运动障碍NYHA >;2(76%)。平均LVEF为55%,这意味着大多数患者保留了左心室射出部分。我们收集的一项重要数据是手术前的等待时间。在纳入的患者(102名)中,从诊断到TAVI植入的平均时间为162天(超过5个月)。冠状动脉造影和TAVI植入之间的时间约为109天,而全国平均时间为70天。在纳入的患者中,13%的人在等待名单上死亡,7%的人拒绝接受建议的治疗。术前工作时间的研究并没有确定任何特定的检测是主要原因,但我们可以得出结论,整个过程有助于这些结果。结论:这项研究表明,在这一人群中,四分之一的严重主动脉狭窄患者目前不能从经皮瓣膜置换中受益。现场管理,不需要心脏手术,可以被认为可以减少等待时间和死亡率,就像欧洲其他地方所做的那样。
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引用次数: 0
Management of Acenocoumarol in Tunisian elderly population : Risk factors of overdose and bleeding 突尼斯老年人口中的醋硝香豆素管理 :用药过量和出血的风险因素
IF 0.3 Q4 Medicine Pub Date : 2025-04-11 DOI: 10.1016/j.ancard.2025.101894
Ines Kechaou , Mohamed Salah Hamdi , Asma Tekaya , Amira Taouay , Eya Cherif , Lamia Ben Hassine

Introduction

Anticoagulant therapy, often required in the elderly, is not without risk. This study aims to investigate the particularities of the use of anticoagulants in the elderly during hospital stay, along with the factors associated with bleeding and overdose.

Results

There were 55 women and 45 men (sex ratio: 0.81), with a mean age of 75.7 ± 6.9 years. The indications for anticoagulant treatment were venous thromboembolism (VTE) (92%) and atrial fibrillation (AF) (8%).
The average duration of treatment with acenocoumarol was 17.22 days ± 7.9. The dose of acenocoumarol initiation was 1 mg in 85% of patients and 2 mg in 15%.
INR < 2 was observed in 15% of patients. INR in the target area was obtained in 47% of patients with a mean dose of 2.33 mg of acenocoumarol. An overdose of acenocoumarol was noted in 38% of patients: average INR at 4.7. Seven patients had bleeding events. An overdose was reported in 4 of them.
Fever, infection, inflammatory syndrome, hypoalbuminemia, hypoprotidemia, and malnutrition were associated with a greater risk of overdose in our patients. Gastroduodenal ulcer disease, past medical history of gastrointestinal bleeding and renal failure were risk factors for bleeding in our patients.

Conclusion

The use of anticoagulants in the elderly requires a comprehensive assessment, including comorbidities, geriatric settings, and social environment.
抗凝治疗常用于老年人,但并非没有风险。本研究旨在探讨老年人住院期间抗凝血剂使用的特殊性,以及与出血和用药过量相关的因素。结果女性55例,男性45例(性别比0.81),平均年龄75.7±6.9岁。抗凝治疗的适应症为静脉血栓栓塞(VTE)(92%)和心房颤动(AF)(8%)。阿塞诺古美尔治疗的平均持续时间为17.22天±7.9天。阿塞诺古豆素起始剂量为85%的患者1mg, 15%的患者2mg。INR & lt;在15%的患者中观察到2。47%的患者平均剂量为2.33 mg阿塞诺古玛罗,靶区获得INR。38%的患者发现阿塞诺古豆醇过量:平均INR为4.7。7例患者出现出血事件。其中4人被报告服药过量。发热、感染、炎症综合征、低白蛋白血症、低蛋白质血症和营养不良与我们的患者用药过量风险增加有关。胃十二指肠溃疡、既往消化道出血和肾功能衰竭是本组患者出血的危险因素。结论老年人抗凝血药物的使用需要综合评估,包括合并症、老年背景和社会环境。
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引用次数: 0
Hémoptysie révélatrice d'une agénésie de l'artère pulmonaire gauche : à propos d'un cas 左肺动脉变性血液病:关于一个病例
IF 0.3 Q4 Medicine Pub Date : 2025-04-11 DOI: 10.1016/j.ancard.2025.101895
Labied Mohamed, Bouzid Ismail, El Oualladi Feryal, Mountassir Chorouk, Lembarki Ghizlane, Sabiri Mouna, Lezar Samira
Unilateral agenesis of the pulmonary artery is a rare congenital malformation. Diagnosis is based on imaging due to the nonspecificity of clinical symptoms. Hemoptysis is among the rare manifestations of this malformation. Standard radiography provides relevant orientation elements; however, CT pulmonary angiography remains the reference examination for positive diagnosis. We report the case of a 47-year-old patient presenting with recurrent episodes of minimal hemoptysis occurring quietly. A CT pulmonary angiography was performed, revealing agenesis of the left pulmonary artery.
单侧肺动脉缺失是一种罕见的先天性畸形。由于临床症状无特异性,诊断主要依靠影像学检查。咯血是这种畸形的罕见表现之一。标准影像学检查可提供相关的定位要素;然而,CT 肺血管造影仍是阳性诊断的参考检查。我们报告了一例 47 岁患者的病例,该患者反复发作轻微咯血,且悄无声息。CT 肺血管造影显示左肺动脉发育不全。
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引用次数: 0
La santé mentale des auxiliaires médicaux en rythmologie interventionnelle 干预节律学医务助理的心理健康
IF 0.3 Q4 Medicine Pub Date : 2025-04-11 DOI: 10.1016/j.ancard.2025.101891
Carole Mette , Karine Petit , Laurent Fauchier
The mental health of allied professionals in interventional electrophysiology is an increasingly concerning topic given the emotional and physical demands inherent in their role, which deserves particular attention. This article examines the impact of stress, anxiety, and burnout on these healthcare professionals. To this end, an anonymous survey of allied professionals in interventional electrophysiology was conducted using a questionnaire via a dedicated survey platform over a period from October 17 to December 10, 2024. The data extracted and analyzed with the help of the platform revealed the following difficulties: lack of recognition, unsatisfactory working conditions, high workload, relational difficulties, and a lack of organization. This has resulted in an impact on the feelings of the allied professionals and especially on their work. In conclusion, this study reveals a generalized feeling of malaise among all allied professionals in interventional electrophysiology on a psychological, emotional, and physical level, as well as the importance of investing in the mental health of allied professionals for the improvement of the entire healthcare system.
介入电生理学专业人员的心理健康是一个越来越受关注的话题,因为他们的角色固有的情感和身体需求,这值得特别关注。本文研究了压力、焦虑和倦怠对这些医疗保健专业人员的影响。为此,在2024年10月17日至12月10日期间,通过专用调查平台使用问卷对介入电生理学相关专业人员进行了匿名调查。在平台的帮助下提取和分析的数据揭示了以下困难:缺乏认可,工作条件不理想,工作量大,关系困难,缺乏组织。这对专职人员的感情造成了影响,特别是对他们的工作造成了影响。综上所述,本研究揭示了介入电生理学专业人员在心理、情绪和身体层面上普遍存在的不适感,以及投资于专业人员心理健康对整个医疗保健系统改善的重要性。
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引用次数: 0
Knowledge, attitudes, and practices of a group of Cameroonian physicians regarding cardiopulmonary resuscitation : a cross-sectional study 一组喀麦隆医生关于心肺复苏的知识、态度和实践:一项横断面研究
IF 0.3 Q4 Medicine Pub Date : 2025-04-11 DOI: 10.1016/j.ancard.2025.101893
Loïc Alban Mbosso Tasong , Junette Arlette Metogo Mbengono-Njoki , Chris Nadège Nganou-Gnindjio

Background

Identification of cardiopulmonary arrest and its immediate and effective management are decisive factors in survival.

Objective

To evaluate the knowledge, attitudes, and practices of Cameroonian physicians concerning cardiopulmonary resuscitation

Methods

We conducted a cross-sectional study among doctors in Douala, Bafoussam, Garoua, and Yaoundé in Cameroon over three months from March 2024 to May 2024. We included specialists, residents/interns, and general practitioners practising in these cities who agreed to participate in the study. Were not included physicians who had been in practice for less than six months in Cameroon. Answers were validated by referring to the European Resuscitation Council 2015 recommendations and the American Heart Association 2020. Means were compared using the ANOVA and Kruskal-Wallis test. The association between different variables was assessed using a χ2 test or an exact Fisher test. A p-value < 0.05 was considered significant.

Results

Of the 95 participants recruited, the median age was 31 (IQR 28- 33), with extremes between 25 and 56. Residents/interns represented the largest group in our population, with 66 (69.5%) participants. We had 56 (58.9%) participants who had already attended a cardiopulmonary resuscitation training course. Participants who had never attended a previous cardiopulmonary resuscitation training course had a significantly lower mean than those who had (9.90 ± 1.93 vs. 11.61 ± 2.80, P = 0.002). Participants whose last training was more than a year ago had a significantly lower mean score than participants whose previous training was less than a year ago (11.05 ± 2.97 vs. 12.78 ± 2.02, P = 0.016). There was a significant difference between participants' means according to the city of exercise (P=0.037). The doctors practising in Yaoundé had more inadequate practices than those practising outside of Yaoundé (OR: 7.607; 95% CI 1.897–30.509; p = 0.005).

Conclusion

Most of our participants' knowledge and practices regarding cardiopulmonary resuscitation were incomplete and inadequate. However, our study noted a positive attitude toward physicians. Therefore, it is essential to emphasise the training of health care providers on cardiopulmonary resuscitation.
背景:心肺骤停的识别和及时有效的处理是影响患者生存的决定性因素。目的评估喀麦隆医生对心肺复苏的知识、态度和实践情况。方法对喀麦隆杜阿拉、巴富萨姆、加鲁瓦和雅温德省的医生进行横断面研究,时间为2024年3月至2024年5月。我们包括在这些城市执业并同意参与研究的专家、住院医师/实习生和全科医生。不包括在喀麦隆执业少于6个月的医生。通过参考欧洲复苏委员会2015年的建议和美国心脏协会2020年的建议,验证了答案。均值比较采用方差分析和Kruskal-Wallis检验。采用χ2检验或精确Fisher检验评估不同变量之间的相关性。p值<;0.05被认为是显著的。结果在招募的95名参与者中,年龄中位数为31岁(IQR 28- 33),极值在25 - 56岁之间。住院医师/实习生是我们人口中最大的群体,有66名(69.5%)参与者。我们有56名(58.9%)参与者已经参加过心肺复苏培训课程。从未参加过心肺复苏培训课程的参与者的平均值显著低于参加过心肺复苏培训课程的参与者(9.90±1.93比11.61±2.80,P = 0.002)。最后一次训练时间在1年以上的参与者的平均得分明显低于前一次训练时间在1年以内的参与者(11.05±2.97∶12.78±2.02,P = 0.016)。不同运动城市的参与者的均值有显著差异(P=0.037)。在雅温顿医生执业的医生比在雅温顿以外执业的医生执业不足的比例更高(OR: 7.607;95% ci 1.897-30.509;P = 0.005)。结论大多数患者心肺复苏知识和实践不完整、不充分。然而,我们的研究注意到对医生的积极态度。因此,必须强调对医护人员进行心肺复苏培训。
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引用次数: 0
Phéochromocytome révélé par une dissection coronaire spontanée : à propos d'un cas inhabituel 自发性冠状动脉切除术揭示的嗜铬细胞瘤:关于罕见病例
IF 0.3 Q4 Medicine Pub Date : 2025-04-11 DOI: 10.1016/j.ancard.2025.101896
Minh Tam Bailly, Marie Arnal, O Labidi, X Cerchez, E Berthelot

Background

Spontaneous coronary artery dissection (SCAD) is a rare and under-diagnosed disease that accounts for 1 to 4% of acute coronary syndromes and nearly one-third of heart attacks in women under the age of 50. We present a unique case of a pheochromocytoma that contributed to SCAD.

Case summary

A 49-year-old patient presented to the emergency department with chest pain that had been evolving for several days. The diagnosis was a late ST ST-segment elevation Myocardial Infarction (STEMI) in the anterior leads. Echocardiography has shown a severe left ventricular dysfunction related to a large akinesis of anterior and lateral segments. Coronary angiography revealed a recent occlusion due to spontaneous dissection of the mid left anterior descending artery and of the first and second obtuse marginal arteries. During the same hospitalization, incidental findings from a CT pulmonary angiography led to the discovery of a left adrenal mass. Subsequent abdominal scanning and blood/urine assays confirmed a diagnosis of pheochromocytoma. The patient underwent follow-up coronary angiography and cardiac MRI to evaluate cardiac involvement before undergoing surgical removal of the pheochromocytoma.
The patient has undergone successful surgical ablation two months after STEMI in a referral center for endocrinology surgery with an optimal cardiological technical platform.

Discussion

Spontaneous coronary artery dissection is a rare and potentially fatal disease and has never been described in the literature in association with a pheochromocytoma. Similar cases require a multidisciplinary approach, as well as surgery carried out in a facility equipped with advanced cardiac techniques. Given the curative potential of pheochromocytoma, early detection of SCAD is essential to reduce the risk of recurrence.
自发性冠状动脉夹层(SCAD)是一种罕见且诊断不足的疾病,占急性冠状动脉综合征的1%至4%,占50岁以下女性心脏病发作的近三分之一。我们提出一个独特的病例嗜铬细胞瘤,有助于SCAD。病例总结:一名49岁的患者因胸痛持续数天就诊于急诊科。诊断为前导联晚期ST段抬高型心肌梗死(STEMI)。超声心动图显示严重的左心室功能障碍与前段和侧段大的运动有关。冠状动脉造影显示最近由于自发剥离的左前降支和第一和第二钝边缘动脉闭塞。在同一住院期间,CT肺血管造影的偶然发现导致发现左肾上腺肿块。随后的腹部扫描和血/尿分析证实了嗜铬细胞瘤的诊断。在手术切除嗜铬细胞瘤之前,患者接受了后续的冠状动脉造影和心脏MRI来评估心脏受累情况。患者在STEMI后两个月在内分泌外科转诊中心接受了成功的手术消融,并获得了最佳的心脏科技术平台。自发性冠状动脉夹层是一种罕见且具有潜在致命性的疾病,文献中从未报道过与嗜铬细胞瘤有关。类似的病例需要多学科方法,并在配备先进心脏技术的设施中进行手术。鉴于嗜铬细胞瘤的治疗潜力,早期发现SCAD对于降低复发风险至关重要。
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引用次数: 0
Editorial board / Ours rédaction 编委会/我们的组织
IF 0.3 Q4 Medicine Pub Date : 2025-03-26 DOI: 10.1016/S0003-3928(25)00020-4
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引用次数: 0
Sommaire 摘要
IF 0.3 Q4 Medicine Pub Date : 2025-03-26 DOI: 10.1016/S0003-3928(25)00022-8
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引用次数: 0
Profil tensionnel et équilibre glycémique du sujet diabétique type 2 et hypertendu au Centre Hospitalier Universitaire Yalgado Ouédraogo : à propos de 116 Cas Yalgado Ouedraogo大学医院中心2型糖尿病和高血压患者的紧张概况和血糖平衡:约116例
IF 0.3 Q4 Medicine Pub Date : 2025-03-15 DOI: 10.1016/j.ancard.2025.101878
Koudougou Jonas Kologo , A. Tall-Thiam , G.R.C. Millogo , K.J. Nabi , S. Traore , Y. Kambire , Z.M. Some , M.R. Kationo , N.V. Yameogo , A.K. Samadoulogou , P. Zabsonre

Objective

To study the correlation between glycaemic control and blood pressure control, in order to determine the factors associated with blood pressure control in diabetic patients.

Methodology

This was a descriptive cross-sectional study with an analytical aim over a period of 7 months. Patients were recruited on an outpatient basis, and all underwent ABPM, measurement of glycated haemoglobin and creatinine levels, and assessment of compliance with treatment.

Results

Our criteria enabled us to select 116 patients. Women predominated (69%). The mean age of the patients was 62 ± 7 years, with a peak between 60 and 70 years. The mean duration of hypertension was 12 years and that of diabetes 6 years. The most frequently associated cardiovascular risk factor was physical inactivity (71.5%), followed by age. 57.8% of patients had uncontrolled blood pressure at the practice, with systolic hypertension predominating (58.2%). MAPA found that 61.6% of patients were controlled, giving a white-coat hypertension rate of 47.8%. Glycaemic control was observed in 42.2% of cases, and 87% of patients had good renal function. Compliance with treatment was good in 53.4% of cases, and dual therapy was the most commonly used treatment modality (44.8%), followed by triple therapy. The factors associated with poor blood pressure control were glycaemic imbalance, lack of compliance and monotherapy. Combination therapy was associated with good blood pressure control.

Conclusion

The association of hypertension and type 2 diabetes is frequent. The risk of occurrence increases with age. ABPM is the best method of assessing blood pressure control. Optimising blood pressure control in hypertensive diabetics requires optimising glycaemic control.
目的 研究血糖控制与血压控制之间的相关性,以确定与糖尿病患者血压控制相关的因素。 方法 这是一项描述性横断面研究,旨在对 7 个月内的情况进行分析。患者在门诊招募,所有患者都接受了 ABPM、糖化血红蛋白和肌酐水平测量,并对治疗依从性进行了评估。女性患者占多数(69%)。患者的平均年龄为 62 ± 7 岁,最高年龄为 60 至 70 岁。高血压的平均病程为 12 年,糖尿病的平均病程为 6 年。最常见的心血管风险因素是缺乏运动(71.5%),其次是年龄。57.8%的患者在就诊时血压未得到控制,其中以收缩期高血压为主(58.2%)。MAPA 发现,61.6% 的患者血压得到控制,白大衣高血压率为 47.8%。42.2%的患者血糖得到控制,87%的患者肾功能良好。53.4%的患者对治疗的依从性良好,双重疗法是最常用的治疗方式(44.8%),其次是三重疗法。血压控制不佳的相关因素包括血糖失衡、缺乏依从性和单一疗法。结论:高血压与 2 型糖尿病的关系很常见。高血压与 2 型糖尿病的关联很常见,发生风险随年龄增长而增加。ABPM 是评估血压控制情况的最佳方法。优化高血压糖尿病患者的血压控制需要优化血糖控制。
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引用次数: 0
期刊
Annales de cardiologie et d'angeiologie
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