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Full-Integer Topological Defects in Polar Active Matter: From Collective Migration to Tissue Patterning 极性活性物质的全整数拓扑缺陷:从集体迁移到组织模式
IF 22.6 1区 物理与天体物理 Q1 PHYSICS, CONDENSED MATTER Pub Date : 2025-12-19 DOI: 10.1146/annurev-conmatphys-031620-105420
Luiza Angheluta, Anna Lång, Emma Lång, Stig Ove Bøe
Polar active matter—including animal herds, aggregates of motile cells, and active colloids—often forms coordinated migration patterns, such as flocking. This orderly motion can be disrupted by full-integer topological defects representing localized disturbances in which directional alignment is lost. Such polar defects can serve as key organizing centers across scales, sustaining collective behavior such as swirling motion and other large-scale coherent states. Although significant progress has been made in understanding active matter principles in recent years, a quantitative understanding of how topological defects influence active polar matter is still needed. We present a brief overview of recent experimental observations in synthetic active colloids and various biological systems. We describe how polar defects mediate dynamical transitions and contribute to the spontaneous emergence of large-scale coherent states. We also discuss theoretical advances in the physical modeling of coupled processes involving polar defects and collective behavior in active polar matter.
极性活性物质——包括动物群、活动细胞聚集体和活性胶体——经常形成协调的迁移模式,如群集。这种有序的运动可能会被全整数拓扑缺陷所破坏,这些缺陷代表了定向对齐丢失的局部扰动。这种极性缺陷可以作为跨尺度的关键组织中心,维持集体行为,如旋转运动和其他大规模的相干状态。尽管近年来在理解活性物质原理方面取得了重大进展,但对拓扑缺陷如何影响活性极物质的定量理解仍然需要。我们提出了一个简短的概述,最近的实验观察合成活性胶体和各种生物系统。我们描述了极性缺陷如何介导动力学转变,并有助于大规模相干态的自发出现。我们还讨论了涉及极性缺陷和活性极性物质集体行为的耦合过程物理建模的理论进展。
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引用次数: 0
The Rheology of Living Tissues: From Cells to Organismal Mechanics 活组织流变学:从细胞到有机体力学
IF 22.6 1区 物理与天体物理 Q1 PHYSICS, CONDENSED MATTER Pub Date : 2025-12-19 DOI: 10.1146/annurev-conmatphys-071125-054711
Sayantani Kayal, Anh Q. Nguyen, Dapeng Bi
Biological tissue rheology investigates the mechanical behavior of tissues, emphasizing their viscoelastic and plastic properties that enable both solid-like elasticity and fluid-like viscosity under mechanical stress. These mechanical characteristics are pivotal in various physiological processes, such as embryonic development, tissue remodeling, wound healing, and pathological conditions including cancer metastasis. The mechanical responses of tissues, shaped by cellular forces and extracellular matrix dynamics, are crucial for maintaining tissue integrity and functionality. Rheological behaviors such as viscoelasticity, plasticity, and active mechanical responses underlie critical biological functions, enabling tissues to adapt structurally and functionally to internal and external stimuli. Recent theoretical and experimental advances have illuminated the complex interplay among cellular mechanics, biochemical signaling, and tissue-level forces, highlighting their roles in governing tissue morphogenesis, repair, and disease progression. This review synthesizes current knowledge, identifies key challenges, and discusses future directions for research in biological tissue rheology.
生物组织流变学研究组织的力学行为,强调它们的粘弹性和塑性特性,使其在机械应力下具有固体样弹性和流体样粘性。这些机械特性在各种生理过程中起着关键作用,如胚胎发育、组织重塑、伤口愈合和包括癌症转移在内的病理状况。由细胞力和细胞外基质动力学形成的组织的机械反应对于维持组织的完整性和功能至关重要。流变行为,如粘弹性、可塑性和主动机械反应,是关键生物功能的基础,使组织能够在结构和功能上适应内部和外部刺激。最近的理论和实验进展已经阐明了细胞力学、生化信号和组织水平力量之间复杂的相互作用,突出了它们在控制组织形态发生、修复和疾病进展中的作用。这篇综述综合了目前的知识,确定了关键的挑战,并讨论了生物组织流变学研究的未来方向。
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引用次数: 0
Self-Organization, Memory, and Learning: From Driven Disordered Systems to Living Matter 自组织、记忆和学习:从驱动无序系统到生命物质
IF 22.6 1区 物理与天体物理 Q1 PHYSICS, CONDENSED MATTER Pub Date : 2025-12-18 DOI: 10.1146/annurev-conmatphys-082225-051908
Muhittin Mungan, Eric Clément, Damien Vandembroucq, Srikanth Sastry
Disordered systems subject to a fluctuating environment can self-organize into a complex history-dependent response, retaining a memory of the driving. In sheared amorphous solids, self-organization is established by the emergence of a persistent system of mechanical instabilities that can repeatedly be triggered by the driving, leading to a state of high mechanical reversibility. As a result of self-organization, the response of the system becomes correlated with the dynamics of its environment, which can be viewed as a sensing mechanism of the system's environment. Such phenomena emerge across a wide variety of soft matter systems, suggesting that they are generic and, hence, may depend very little on the underlying specifics. We review self-organization in driven amorphous solids, concluding with a discussion of what self-organization in driven disordered systems can teach us about how simple organisms sense and adapt to their changing environments.
受波动环境影响的无序系统可以自组织成复杂的依赖于历史的响应,保留对驾驶的记忆。在剪切的非晶态固体中,自组织是通过持续的机械不稳定系统的出现而建立的,该系统可以通过驱动反复触发,从而导致高机械可逆性状态。由于自组织,系统的响应与其环境的动态相关,这可以看作是系统对环境的感知机制。这种现象出现在各种各样的软物质系统中,表明它们是通用的,因此可能很少依赖于潜在的细节。我们回顾了驱动非晶固体中的自组织,最后讨论了驱动无序系统中的自组织可以告诉我们简单生物如何感知和适应不断变化的环境。
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引用次数: 0
Deformed States in Paraelectric and Ferroelectric Nematic Liquid Crystals 准电和铁电向列液晶中的变形态
IF 22.6 1区 物理与天体物理 Q1 PHYSICS, CONDENSED MATTER Pub Date : 2025-12-17 DOI: 10.1146/annurev-conmatphys-031424-011954
Oleg D. Lavrentovich
Ground states of materials with orientational order ranging from solid ferromagnets and ferroelectrics to liquid crystals often contain spatially varying vector-like order parameter caused by inner factors such as the shape of building units or by the geometry of confinement. This review presents examples of how the shapes, chirality, and polarity of molecules and spatial confinement induce deformed equilibrium and polydomain states with parity breaking, splay, bend, and twist-bend deformations of the order parameter in paraelectric and ferroelectric nematic liquid crystals. Parity breaking results either from chirality of the constituent molecules, as a replacement of energetically costly splay and bend in paraelectric nematics, or in response to a depolarization field in the ferroelectric nematic. Both paraelectric and ferroelectric nematics exhibit a splay cancellation effect, in which the elastic and electrostatic energies of splay along one direction are reduced by an additional splay along orthogonal directions.
从固体铁磁体、铁电体到液晶等取向有序材料的基态中,往往包含空间变化的类矢量有序参数,这是由结构单元的形状或约束的几何形状等内部因素引起的。本文介绍了分子的形状、手性和极性以及空间约束如何在对电和铁电向列液晶中引起宇称破缺、展、弯和扭-弯等序参量变形的变形平衡和多畴态。宇称破缺要么是由组成分子的手性引起的,作为对电向列中能量昂贵的张开和弯曲的替代,要么是对铁电向列中去极化场的响应。准电向列和铁电向列都表现出一种斜向抵消效应,即沿一个方向的斜向的弹性能和静电能被沿正交方向的额外斜向减小。
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引用次数: 0
Statistical Field Theory of Equilibrium Amorphous Solids and the Intrinsic Heterogeneity Distributions that Characterize Them 平衡非晶固体的统计场论及表征它们的本征非均质分布
IF 22.6 1区 物理与天体物理 Q1 PHYSICS, CONDENSED MATTER Pub Date : 2025-12-17 DOI: 10.1146/annurev-conmatphys-071125-063050
Paul M. Goldbart
A rich variety of amorphous solids are found throughout nature, science, and technology, including those formed via the vulcanization of long, flexible polymer molecules. A special class—those featuring a wide separation between the very long timescales on which constraining bonds release and the much shorter timescales on which unconstrained degrees of freedom relax—exhibit equilibrium states and are therefore amenable to equilibrium statistical mechanics. A review is given of the least detailed (and thus most general) approach to equilibrium amorphous solids: statistical field theory. The field at the center of this theory is motivated by the aim of characterizing the amorphous solid state. This field, and the theory that governs it, turn out to be rather unusual in essential ways. What the statistical field theory approach predicts—and can predict—is discussed, including the following: the emergence of the solid and its intrinsic heterogeneity; fluctuations and connections with percolation; symmetry breaking and elasticity; and correlations and the information they furnish. Emphasis is placed on the idea, particular to amorphous solids, that such solids are naturally characterized in terms of distributions that describe the spatial heterogeneity of the thermal motions of their constituents. This information is subtly encoded in the wave vector dependencies of the average field and its correlations. The review concludes with some reflections on the applicability—or otherwise—of the ideas and results it explores to a variety of amorphous solids and related systems.
在自然界、科学和技术中发现了各种各样的无定形固体,包括那些通过长而灵活的聚合物分子硫化形成的固体。有一种特殊的类——在约束键释放的很长的时间尺度和无约束自由度松弛的很短的时间尺度之间有很大的分离——表现出平衡状态,因此适用于平衡统计力学。回顾了最不详细(因此也是最一般)的方法来平衡非晶固体:统计场论。这个理论中心的场是由表征非晶固体状态的目的所激发的。这个领域,以及支配它的理论,在本质上是相当不寻常的。讨论了统计场理论方法预测和能够预测的内容,包括:固体的出现及其内在异质性;波动及其与渗流的联系;对称性破缺与弹性;以及相关性和它们提供的信息。重点放在思想上,特别是无定形固体,这类固体的自然特征是根据分布来描述其组成部分的热运动的空间异质性。这些信息被巧妙地编码在平均场及其相关性的波矢量依赖关系中。最后,对所探索的思想和结果在各种非晶固体和相关体系中的适用性进行了一些思考。
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引用次数: 0
Phase Separation in Mixtures of Nematic and Isotropic Fluids 向列和各向同性流体混合物中的相分离
IF 22.6 1区 物理与天体物理 Q1 PHYSICS, CONDENSED MATTER Pub Date : 2025-12-02 DOI: 10.1146/annurev-conmatphys-031324-024345
Margarida M. Telo da Gama, Rodrigo C.V. Coelho
Mixtures of nematic liquid crystals and isotropic fluids present a rich platform to explore the interplay between orientational order and concentration fluctuations, both experimentally and theoretically. These systems exhibit a wealth of phase behaviors and interfacial phenomena, shaped by the coupling of thermodynamic and kinetic effects. In this review, we present a unified theoretical framework that combines the Landau–de Gennes free energy for nematic ordering with the Cahn–Hilliard description of phase separation. This minimal model captures a wide range of characteristic behaviors, from phase separation and spinodal decomposition to the emergence of anisotropic domains and defect structures driven by the competition between interfacial anchoring and elastic interactions. We analyze the stability of the uniform isotropic and nematic phases and the phase separation dynamics and the interfacial behaviors that arise, and we reference the role of hydrodynamic interactions. The scope is further broadened by reference to active nematic emulsions, in which internal stresses drive nonequilibrium dynamics and novel steady states. Together, these phenomena underscore the versatility of nematic–isotropic mixtures as model systems in soft condensed matter physics.
向列液晶和各向同性流体的混合物为探索取向顺序和浓度波动之间的相互作用提供了丰富的实验和理论平台。这些体系表现出丰富的相行为和界面现象,由热力学和动力学效应的耦合形成。在这篇综述中,我们提出了一个统一的理论框架,结合了向列有序的朗多-德-热讷自由能和相分离的卡恩-希利亚德描述。这个最小模型捕获了广泛的特征行为,从相分离和spinodal分解到界面锚定和弹性相互作用之间竞争驱动的各向异性域和缺陷结构的出现。我们分析了均匀各向同性和向列相的稳定性以及相分离动力学和界面行为,并参考了水动力相互作用的作用。范围进一步扩大了参考主动向列乳剂,其中内应力驱动非平衡动力学和新的稳定状态。总之,这些现象强调了向列-各向同性混合物作为软凝聚态物理模型系统的多功能性。
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引用次数: 0
Multiphase-Field Models of Tissues 组织的多相场模型
IF 22.6 1区 物理与天体物理 Q1 PHYSICS, CONDENSED MATTER Pub Date : 2025-12-02 DOI: 10.1146/annurev-conmatphys-060625-061354
Siavash Monfared, Aleksandra Ardaševa, Amin Doostmohammadi
Understanding how cells coordinate their behaviors to produce large-scale patterns and functions is central to deciphering biological processes ranging from tissue development and regeneration to cancer progression and morphogenesis. Despite advances in imaging and mechanical characterization, the role of physical forces in collective cell dynamics remains incompletely understood. Physics-based models are essential for complementing experimental data, offering access to high-resolution spatiotemporal fields, and enabling mechanistic insights into complex multicellular systems. This review focuses on dense, soft tissues, in which the mechanical deformation of one cell drives reorganization of its neighbors, giving rise to emergent behaviors such as orientational order and long-range force transmission. The multiphase-field model provides a powerful and versatile framework to investigate such systems, bridging biological phenomena and the nonequilibrium physics of active matter. We discuss the theoretical foundations of the model and its applications to a range of biological contexts, including cell migration, heterogeneous populations, confined geometries, and metastasis. We also emphasize the integration of simulations with experimental data, highlighting how this approach is reshaping our understanding of tissue mechanics, collective order, and force transmission. Finally, we outline current trends and future challenges in applying multiphase-field models to biology and soft matter physics.
了解细胞如何协调它们的行为以产生大规模的模式和功能,对于破译从组织发育和再生到癌症进展和形态发生的生物过程至关重要。尽管在成像和力学表征方面取得了进展,但物理力在集体细胞动力学中的作用仍然不完全清楚。基于物理的模型对于补充实验数据、提供高分辨率时空场的访问以及实现对复杂多细胞系统的机制洞察至关重要。这篇综述聚焦于致密的软组织,其中一个细胞的机械变形驱动其相邻细胞的重组,从而产生诸如定向秩序和远程力传递等紧急行为。多相场模型为研究这些系统提供了一个强大而通用的框架,将生物现象和活性物质的非平衡物理联系起来。我们讨论了该模型的理论基础及其在一系列生物学背景下的应用,包括细胞迁移、异质群体、受限几何和转移。我们还强调了模拟与实验数据的整合,强调了这种方法如何重塑我们对组织力学、集体秩序和力传递的理解。最后,我们概述了将多相场模型应用于生物学和软物质物理学的当前趋势和未来挑战。
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引用次数: 0
’t Hooft Anomalies in Metals 《金属异常》
IF 22.6 1区 物理与天体物理 Q1 PHYSICS, CONDENSED MATTER Pub Date : 2025-11-17 DOI: 10.1146/annurev-conmatphys-031524-070514
Dominic V. Else
I review some recent results on understanding the physics of metals in an exact nonperturbative way through the powerful field-theoretic concepts of emergent symmetries and ’t Hooft anomalies. A ’t Hooft anomaly is a discrete topological property that quantum field theories with global symmetries can have. I explain how many of the properties of metals can in fact be viewed as direct consequences of the anomaly. This allows a structural understanding of metals, including non-Fermi liquids, to be obtained even in the absence of any exact solution for the strongly coupled dynamics. I then outline the main limitations and outstanding questions.
我回顾了一些最近的结果,通过强大的场理论概念的涌现对称性和' t Hooft异常,以精确的非摄动方式理解金属的物理。A ' t Hooft异常是具有全局对称性的量子场论所具有的离散拓扑性质。我解释了金属的许多特性实际上可以被视为异常的直接后果。这使得对金属的结构理解,包括非费米液体,即使在没有任何强耦合动力学的精确解的情况下也能得到。然后,我概述了主要的限制和突出的问题。
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引用次数: 0
Quantum-Stabilized States in Magnetic Dipolar Quantum Gases 磁偶极量子气体中的量子稳定态
IF 22.6 1区 物理与天体物理 Q1 PHYSICS, CONDENSED MATTER Pub Date : 2025-11-11 DOI: 10.1146/annurev-conmatphys-061125-032048
Lauriane Chomaz
Ultracold Bose gases of highly magnetic atoms exhibit unique interaction properties that lead to striking many-body behaviors, both at and beyond the mean field. A decade ago, a universal stabilization mechanism driven by quantum fluctuations was discovered in these gases. This mechanism prevents the systems from collapsing and instead allows exotic states of matter to arise, including ultradilute quantum droplets, crystallized quantum states, and especially supersolids. After introducing key features of dipolar quantum Bose gases—including their interactions, ground states, and excitations in a mean-field framework, as well as the onset of quantum-fluctuation stabilization—we review the progress made in understanding the emergence and intriguing properties of these quantum stabilized states. Both theory and experiments are discussed.
高磁性原子的超冷玻色气体表现出独特的相互作用特性,导致惊人的多体行为,无论是在平均场还是在平均场之外。十年前,在这些气体中发现了一种由量子涨落驱动的普遍稳定机制。这种机制可以防止系统崩溃,而是允许物质的奇异状态出现,包括超稀量子液滴,结晶量子态,尤其是超固体。在介绍了偶极量子玻色气体的主要特征——包括它们的相互作用、基态和平均场框架中的激发,以及量子涨落稳定的开始——之后,我们回顾了在理解这些量子稳定状态的出现和有趣特性方面取得的进展。从理论和实验两方面进行了讨论。
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引用次数: 0
Two-Dimensional Bulk Ferroics 二维块状铁
IF 22.6 1区 物理与天体物理 Q1 PHYSICS, CONDENSED MATTER Pub Date : 2025-10-13 DOI: 10.1146/annurev-conmatphys-060925-103154
Qian Song, Riccardo Comin
The discovery of ferroic orders in two-dimensional (2D) van der Waals (vdW) materials has introduced new functionalities to the 2D materials family, potentially revolutionizing next-generation nanoelectronics and spintronics. We provide a concise review of recent advances in 2D ferroics, with a focus on their experimental observations, the unique properties emerging from reduced dimensionality, and promising applications. We conclude by discussing key challenges that remain and offering our outlook on future research directions in this rapidly evolving field.
二维(2D)范德华(vdW)材料中铁有序的发现为二维材料家族引入了新的功能,可能会彻底改变下一代纳米电子学和自旋电子学。我们简要回顾了二维铁材料的最新进展,重点是他们的实验观察,从降维中出现的独特性质,以及有前景的应用。最后,我们讨论了仍然存在的主要挑战,并对这个快速发展的领域的未来研究方向提出了展望。
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引用次数: 0
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Annual Review of Condensed Matter Physics
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