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Effectiveness of The Coastal Tourist Nursing Model to Improve Balawista Behaviour in Bali Province 巴厘省沿海游客护理模式改善Balawista行为的有效性
Pub Date : 2021-02-01 DOI: 10.36295/ASRO.2021.24344
K. Achjar, J. Sahar, Lita Heni Kusumawardani
Introduction: Indonesia is an archipelagic country which is surrounded by coasts with great potential to develop the existing tourism sector. Objective: The aim of this research is to improve the coastal tourist nursing model to improve the behaviour of the Balawista (the coastal rescuer team).The coastal tourist nursing model is a part of community nursing. Method: The design of this research is operational research with three phaseswhich are phase I problem identification, phase II model and module development andphase III the coastal tourist nursing model trial through the establishment of a coastal health post by using quantitative quasi experimental research post-test with the control group, with a cluster sampling technique.The coastal tourist nursing model was carried out on the coast of Central Kuta sub-district, Badung Regency in 118 Balawistas. The statistical test used was chi square, t-test, multiple linear regression test and General linier Model Repeated Measure (GLM-RM). Results: The results obtainedwere that the coastal tourist nursing model wasproven to affect the Balawista’sbehaviour. Therefore this model can be used as one of the health efforts based on the communitywithin the coastal community in Indonesia.
印度尼西亚是一个被海岸包围的群岛国家,具有发展现有旅游业的巨大潜力。目的:改进海岸游客护理模式,改善海岸救援队伍的行为。沿海旅游护理模式是社区护理的一个组成部分。方法:采用整群抽样方法,采用定量准实验研究的方法,通过建立沿海卫生站,对沿海游客护理模式进行实证研究,分为三个阶段,即第一阶段问题识别、第二阶段模型与模块开发和第三阶段。在118 Balawistas巴东县中部库塔街道海岸开展了海岸旅游护理模式。统计检验采用卡方检验、t检验、多元线性回归检验和一般线性模型重复测量(GLM-RM)。结果:沿海旅游护理模式对Balawista的行为有一定的影响。因此,该模型可以作为印度尼西亚沿海社区中基于社区的卫生工作之一。
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引用次数: 0
Vital signs changes during manual and ultrasonic scaling 人工和超声波洗洁时生命体征变化
Pub Date : 2021-02-01 DOI: 10.36295/ASRO.2021.24242
Ali Arkan Redha Alsagban, Tameem Jassim, R. Salah, A. Abdulkareem
Background: Blood pressure (BP) and pulse rate (PR) are important vital signs for basic body performance. In spite of the effect of dental anxiety on vital signs, other cofactors should also be considered. Aims: The study aimed to investigate vital signs measurements changes before and after ultrasonic and manual scaling, andto investigate the effect of other cofactors such as waiting time, and route of attending the dental clinic. Settings and Design:A cross-sectional design study. Methods and Methods: Two-hundred and forty patients were enrolled in this study. The waiting time before the clinical session, and the route by which the patient reached the clinic were determined.Whereas, BP and PR were measured at the clinical session before and after scaling. Statistical analysis used: Paired t-test was used in this study. Results: A significant reduction in PR among patients after receiving scaling was observed. Moreover, a significant reduction in PR was observed in those patients who didn’t wait prior treatment, reached the clinic via stairs, and received ultrasonic scaling. Before and after scaling non-significant change in BP of the patients was observed. However, the reduction in systolic BP after scaling was non-significant when the patient reached the clinic via elevator, while there was a significant reduction in systolic BP when the patient used stairs. Conclusions: Scaling might reduce patient dental anxiety.Additionally,the waiting time before the clinical session and the route by which the patient reached the clinic could also reduce relative changes in BP and PR. Key-words: blood pressure, periodontal disease, dental anxiety. How to cite this article: Alsagban AA, Jassim TK, et al (2021): Vital signs changes during manual and ultrasonic scaling, Ann Trop Med & Public Health; 24(S2): SP24242. DOI: http://doi.org/10.36295/ASRO.2021.24242 sagban et al (2021): Vital signs in manual and ultrasonic scaling Feb 2021 Vol. 24 Issue 2 Annals of Tropical Medicine & Public Health http://doi.org/10.36295/ASRO.2021.24242 Key Messages: (i) What is already known; Scaling is associated with dental anxiety which is a stress factor that was found to have an impact on vital signs. (ii) What the research adds; This study investigated how much time was spent in the waiting room prior to scaling and the route by which the patient reached clinic i.e. stairs or elevator. (iii) What methodology was adopted; A cross-sectional clinical study design. (iv) What are the limitations and suggestions for future studies; Future studies are suggested toinvestigate other variables and increasing the number of participants.
背景:血压(BP)和脉搏率(PR)是机体基本机能的重要生命体征。除了牙齿焦虑对生命体征的影响外,还应考虑其他辅助因素。目的:探讨超声和人工洗牙前后患者生命体征指标的变化,并探讨其他辅助因素如等待时间、就诊路线等的影响。设置和设计:一项横断面设计研究。方法和方法:240例患者入组研究。确定了临床会诊前的等待时间和患者到达诊所的路线。而在标度前后的临床阶段测量血压和PR。采用统计学分析:本研究采用配对t检验。结果:观察到患者接受刮片后PR显著降低。此外,那些没有等待治疗的患者,通过楼梯到达诊所,并接受超声洗洁术,PR显著降低。刮尺前后患者血压无明显变化。然而,当患者通过电梯到达诊所时,缩放后的收缩压降低不显著,而当患者使用楼梯时,收缩压明显降低。结论:洗牙可减少患者的牙科焦虑。此外,就诊前的等待时间和患者到达诊所的路线也可以降低血压和PR的相对变化。关键词:血压,牙周病,牙科焦虑。Alsagban AA, Jassim TK,等(2021):人工和超声洗洁术中生命体征的变化,Ann Trop医学与公共卫生;24 (S2): SP24242。DOI: http://doi.org/10.36295/ASRO.2021.24242 sagban等人(2021):人工和超声波缩放的生命体征2021年2月第24卷第2期热带医学与公共卫生年鉴http://doi.org/10.36295/ASRO.2021.24242关键信息:(i)已知的;剔牙与牙齿焦虑有关,这是一种压力因素,被发现对生命体征有影响。研究补充的内容;这项研究调查了在攀登之前在候诊室花费的时间以及患者到达诊所的路线,即楼梯或电梯。采用了什么方法;横断面临床研究设计。有哪些限制和对未来研究的建议;未来的研究建议调查其他变量并增加参与者的数量。
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引用次数: 0
The dominant genotypes of influenza virus and their correspondence to the vaccine strain used in the year 2019-2020 流感病毒的主要基因型及其与2019-2020年使用的疫苗株的对应关系
Pub Date : 2021-02-01 DOI: 10.36295/ASRO.2021.24209
M. A. Ahmed, A. Hasan, N. Mohamed, I. Aufi, F. M. Owaid
Absract: Respiratory tract infection is the most common cause of illness, especially in developing countries. Influenza remains a major public health problem and an endemic respiratory disease in Iraq, therefore this study was conducted to identify the influenza virus (IV) Types and subtype existed. 2515 nasopharyngeal swaps taken from a hospitalized patients suffering from acute respiratory tract infection a cross sectional study was conducted in Iraq from January 2019 to February 2020. The RT-qPCR was used to detect human IV, and IV genotypes among the study population. The (IV) surveillance showed (33.44%) of tested samples were found positive to the influenza virus including two types A 25.45% , and B11.96%. influenza A subtype which contains H1N1 17.41%, and H3N2 4.05%, and Type B Victoria was represented of positive infection. These findings indicated that subtype H1N1 is the dominant strain in Iraq. The age group under 15 years old is considered the most vulnerable to contracting Influenza type A H1N1 25% and type B viruses (40%) followed by the age group 30-45 years old. On the other hand, the age group 15-30 recorded the highest infection rate 25% out of the total H3N2. The non-significant percentage related to the age of over 75 years to all types and subtypes. Baghdad has the high significances incidence of influenza Type A, and B with the percentage 65.92%, and 52.16% respectively of the total tested cases, followed by Dohuk Governorate by percentage 7.2%, 11.96% respectively. Infections of influenza A subtypes H1N1, and H3N2 were distributed differently among governorates, as the subtype prevailed H1N1 in the governorates Baghdad, Dohuk 5.7%, Diyala 6.84%, Salahaddin 2.05%, The Qar 1.83% respectively, while the subtype H3N2 prevailed in the governorates Anbar 30.4%, Baghdad 17.2%, Erbil 14.70%, Dohuk 13.72%, Basra 9.8/5, Diwaniya 2.94% respectively. The epidemic spread of the virus showed earlier primary peak began from October until the end of February, an increase in infection rates rising in the winter months in both the types Influenza type A with the highest peak in a December, and a decline in the summer of type B and a decrease in the subtype H2N3.
摘要:呼吸道感染是最常见的疾病原因,特别是在发展中国家。流感仍然是伊拉克的一个主要公共卫生问题和一种地方性呼吸道疾病,因此进行这项研究是为了确定存在的流感病毒(IV)类型和亚型。2019年1月至2020年2月在伊拉克进行了一项横断面研究,从患有急性呼吸道感染的住院患者中提取了2515例鼻咽交换。采用RT-qPCR检测研究人群的人IV型和IV基因型。(四)监测结果显示,流感病毒阳性率为33.44%,其中A型为25.45%,b型为11.96%。其中甲型H1N1为17.41%,H3N2为4.05%,乙型维多利亚型为阳性。这些结果表明,亚型H1N1是伊拉克的优势毒株。15岁以下年龄组被认为最容易感染甲型H1N1流感病毒25%和乙型流感病毒(40%),其次是30-45岁年龄组。另一方面,15-30岁年龄组的感染率最高,占H3N2总感染率的25%。在所有类型和亚型中,年龄在75岁以上的比例不显著。其中,巴格达省甲型和乙型流感发病率较高,分别占总检测病例的65.92%和52.16%,其次是杜胡克省,分别占7.2%和11.96%。甲型流感H1N1亚型和H3N2亚型在各省的感染率存在差异,其中巴格达、杜胡克、迪亚拉、萨拉哈丁、卡尔的H1N1亚型感染率分别为5.7%、6.84%、2.05%和1.83%,而H3N2亚型在安巴尔、巴格达、17.2%、埃尔比勒、杜胡克、13.72%、巴士拉、9.8/5和迪瓦尼耶的感染率分别为30.4%、14.70%和2.94%。该病毒的流行传播表现为10月至2月底出现较早的初发高峰,A型流感的感染率均在冬季上升,在12月达到最高峰,B型流感在夏季有所下降,H2N3亚型有所减少。
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引用次数: 0
The Effect of Negative Pressure (20 kPa and 25 kPa) Endotracheal Open Suction on the Hemodynamics Indices among Patients in Intensive Care Unit 负压(20 kPa和25 kPa)气管内开放吸引对重症监护病房患者血流动力学指标的影响
Pub Date : 2021-02-01 DOI: 10.36295/ASRO.2021.24355
Sri Suparti, Asiandi, Rasiman
Bacground: In general, patients treated in the Intensive Care Unit (ICU) require the installation of endotracheal tubes (ETT) and ventilators. Suction is an intervention to prevent airway obstruction and maintain airway patency. If ETT suction procedure in terms of regulation and suction duration is not applied correctly, critically ill patients would suffer from haemodynamic problem. Objective:The purpose of this study was to determine the effect of negative suction pressure on hemodynamic indices of patients. Methods:This research is a quantitative study using the quasy experimental method with a pre and post test design without a control group involving 40 respondents taken by accidental sampling technique with repeated measurements. Patient observation sheets, medical records, and treatment records were used to collect the data. Inclusion criteria were adult patients ≥15 years old with ETT and ventilator while the exclusion criteria was the patients with a diagnosis of pneumonia and incomplete observations. Statistical analysis was applied by paired and independent t-test Results: The paired t-test showed a significant difference in the mean of SpO2, RR, HR and MAP, before and after suction with p value <0.05 in each group.There was a difference in the mean of arterial pressure (MAP) between the two groups with p value = 0.003 (<0.01). Whereas hemodynamic indicators (SpO2, RR and HR) did not show any difference (p>0.001). Discussion: Both of these pressures are safe to use in open ETT suction, because the increase in hemodynamics is within the safe limits, however suction must be carried out according to procedure and must be properly monitored.
背景:一般情况下,在重症监护病房(ICU)治疗的患者需要安装气管插管(ETT)和呼吸机。吸痰是一种预防气道阻塞和维持气道通畅的干预措施。如果在抽吸过程的调节和抽吸时间上应用不当,危重患者会出现血流动力学问题。目的:探讨负压吸入对患者血流动力学指标的影响。方法:本研究采用准实验方法,采用前后测试设计,不设对照组,采用重复测量的偶然抽样技术,选取40名被调查者进行定量研究。使用患者观察单、医疗记录和治疗记录收集数据。纳入标准为年龄≥15岁且有ETT和呼吸机的成人患者,排除标准为诊断为肺炎且观察不完全的患者。采用配对t检验和独立t检验进行统计学分析结果:配对t检验显示吸痰前后SpO2、RR、HR、MAP均值差异有统计学意义(p值为0.001)。讨论:这两种压力在开放式气管内吸痰中都是安全的,因为血流动力学的增加在安全范围内,但是吸痰必须按照程序进行,必须适当监测。
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引用次数: 0
Early Diagnosis of Ocular Toxoplasmosis Using Nested PCR Technique for Identification B1Gene from Blood Samples 巢式PCR技术在眼弓形虫病早期诊断中的应用
Pub Date : 2021-02-01 DOI: 10.36295/ASRO.2021.24243
Ghada Basi Ali Alomash
The most common form of posterior uveitis is the one triggered by the protozoan parasite Toxoplasma gondii namely ocular toxoplasmosis (OT).The current conducted work was aimed at early identifying ocular toxoplasmosis employing the use of a nested polymerase chain reaction (nPCR), for targeted T. gondii related B1 gene using two sets of primers, and a latex agglutination (LA) test as routine serological diagnosis for toxoplasmosis. This study consisted of collecting 62 blood samples from patients with a physician-recognized OT that visited Al-Diwaniyah General Teaching Hospital, Al-Diwaniyah City, Iraq, for eye-health related problems. The findings of the LA uncovered various incidence rates distributed over a classified range of ages, genders, and residential areas (urban vs rural); however, a 41 (66.13%) positive infection rate was revealed in general for all categories. Moreover, the firstrun-PCR outcomes demonstrated a 32 (51%) positive identification rate; however, the remaining negative samples were subjected the second-run nested PCR that showed 25 (83%) of positive detection rate of the B1 gene, which, in total, declares that 57 (91%) of the patients were OT-infected. The current study reveals successful use of blood samples for early detection of T. gondii caused uveitis devoting the utilization of the PCR method that targeted the B1 gene.
最常见的后葡萄膜炎是由弓形虫引起的,即眼弓形虫病。目前开展的工作旨在利用巢式聚合酶链反应(nPCR)早期识别眼部弓形虫病,使用两组引物靶向弓形虫相关B1基因,并将乳胶凝集(LA)试验作为弓形虫病的常规血清学诊断。本研究收集了62份来自伊拉克Al-Diwaniyah市Al-Diwaniyah综合教学医院的经医生认可的OT患者的血液样本,这些患者因眼睛健康相关问题而就诊。洛杉矶的调查结果揭示了不同年龄、性别和居住区(城市与农村)的发病率分布;但总体阳性率为66.13%(41)。此外,首次pcr结果显示32(51%)阳性鉴定率;而对其余阴性样本进行二次巢式PCR检测,B1基因阳性检出率为25(83%),总计57(91%)患者为ot感染。目前的研究表明,利用针对B1基因的PCR方法,成功地利用血液样本早期检测弓形虫引起的葡萄膜炎。
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引用次数: 0
The Differences of Sleep Quality between Nurses with Two-shifts of Work and Nurses with Three-shifts of Work 两班倒护士与三班倒护士睡眠质量的差异
Pub Date : 2021-02-01 DOI: 10.36295/ASRO.2021.24361
Indriani Mendrofa, Pingkan Natasya Goni, Martina Pakpahan, Dora Irene Purimahua
Objectives: Humans generally have two times, which are daytime for activity and night for rest (circadian rhythm). Shift system of working can cause a lack of sleep or disruption of a person's sleep cycle, especially those who have a night shift. The shift of working can cause sleep deprivation of the nurses. This study aim was to identify the differences in sleep quality between nurses with two-shifts of work and nurses with three-shifts of work. Method: This study conducted on June-July 2019 in one private hospital in Jakarta, with a cross-sectional approach. This study used quantitative method. The sample of this study was 90 nurses (two-shifts: n=35; three-shifts: n= 55). Pittsburgh Sleep Quality Index was used as the instrument that has passed for Validity and Reliability (Chronbach alpha=0.820). Univariate and Mann-Whitney U were used to analyze the data. Results: This study found that most of the respondents were women (83,3%), range of ages 26-65 (51,11%), and nurses with two-shifts have poor sleep quality as 15.56%, nurses with three-shifts have poor sleep quality as 46.67%. There are differences in sleep quality between nurses with two-shifts and nurses with three-shifts (p value= 0.002). Conclusion: The shift work system can cause poor sleep quality of the nurses, especially for the nurses with threeshifts. Future researches expected to explore the factors that affect the poor sleep quality of nurses.
目的:人类通常有两个时间,白天活动,晚上休息(昼夜节律)。轮班制会导致睡眠不足或打乱一个人的睡眠周期,尤其是那些上夜班的人。轮班工作会导致护士睡眠不足。本研究旨在探讨两班倒护士与三班倒护士在睡眠质量上的差异。方法:本研究于2019年6月至7月在雅加达一家私立医院进行,采用横断面方法。本研究采用定量方法。本研究样本为90名护士(两班制:n=35;三班倒:n= 55)。采用匹兹堡睡眠质量指数作为效度和信度通过的工具(Chronbach alpha=0.820)。采用单变量和Mann-Whitney U对数据进行分析。结果:本研究发现,受访护士中以女性居多(83.3%),年龄在26-65岁之间(51.11%),两班倒护士睡眠质量差的比例为15.56%,三班倒护士睡眠质量差的比例为46.67%。两班倒护士与三班倒护士的睡眠质量存在差异(p值= 0.002)。结论:倒班制会导致护士睡眠质量差,三班制护士睡眠质量差。未来的研究有望进一步探讨护士睡眠质量差的影响因素。
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引用次数: 0
Evaluation of Anti-Psoriatic Effects of Ellagic Acid on Imiquimod Induced Psoriatic-Like Dermatitis in Mice 鞣花酸对咪喹莫特诱导小鼠银屑病样皮炎的抗银屑病作用评价
Pub Date : 2021-02-01 DOI: 10.36295/ASRO.2021.24216
Ehab Habeeb Abudlqader, H. Kadhim
Ellagic acid is polyphenolic compound which is present in many fruits. Many pharmacological properties of Ellagic acid have been reviewed and described for many years. Some properties study in animals, while the other have been evaluated in humans including anti-inflammatory, neuroprotective, and Hepatoprotective effects, as well as the protection it provides against diabetes, cardiovascular disease, and cancer. In this study we investigated the effect of Ellagic acid on induced psoriatic-like dermatitis in mice. In this study, 50 mice were involved, divided into 5 groups (10 group of each). Except Group I (healthy), all group received Imiquimod for psoriasis induction during all days of experiment. Group II Induced and without treatment and the other groups III, IV and V were induced and treated twice daily with wool fat, 0.05% Clobetasol propionate, 5% Ellagic acid respectively, from day 7 until the end of experiment. The result showed that Ellagic acid has anti-psoriatic effect by significant decreasing the PASI score and ameliorating the histological changes that induced by IMQ and by significant decreasing the concentration of skin TNF-alpha as compared to induced group (II), and also significant decreasing the concentration of skin VEGF and pJAK3 as compared to induced group II and vehicle group III. In conclusion, the therapeutic effect of Ellagic acid against Imiquimod-induced psoriasis probably through mechanistic pathway involved anti-inflammatory, anti-proliferative and anti-angiogenesis effect.
鞣花酸是一种多酚化合物,存在于许多水果中。鞣花酸的许多药理特性已经被研究和描述了很多年。一些特性在动物身上进行了研究,而另一些特性已经在人类身上进行了评估,包括抗炎、神经保护和肝脏保护作用,以及它对糖尿病、心血管疾病和癌症的保护作用。本研究探讨了鞣花酸对小鼠银屑病样皮炎的影响。本研究选用50只小鼠,分为5组(每组10只)。除ⅰ组(健康)外,其余各组在实验期间均给予咪喹莫特诱导银屑病。II组诱导和不处理,III组、IV组和V组分别用毛脂、0.05%丙酸氯倍他索、5%鞣花酸诱导和处理,每日2次,从第7天起至试验结束。结果表明,与诱导组(II)相比,鞣花酸可显著降低PASI评分,改善IMQ诱导的组织学改变;与诱导组(II)相比,鞣花酸可显著降低皮肤tnf - α浓度;与诱导组(II)相比,鞣花酸可显著降低皮肤VEGF和pJAK3浓度。综上所述,鞣花酸对吡喹莫德所致银屑病的治疗作用可能通过抗炎、抗增殖和抗血管生成等机制实现。
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引用次数: 0
The Effect Of Healthy Heart Gymnastics On The Physical Freshness Of Athletes Weightlifters Padang City 心脏健康体操对巴东市举重运动员身体新鲜度的影响
Pub Date : 2021-02-01 DOI: 10.36295/ASRO.2021.24365
H. Syampurma, Arie Asnaldi, R. Sepriani, Roma Irawan, ArfinDeriListiandi, D. Budi, RifqiFestiawan
Introduction: Judging by the phenomenon and the weightlifting exercise program reported by coaches, weightlifters are more to perform exercises for increased muscle strength in the form of weight training exercises. Exercises in the form of physical conditions or fitnes s exercises for invisible athletes are implemented in the training program. As a result, the weight lifting athlete has a physical freshness in a less good category (less good S/d enough). Objective: The goal of the study was to see the positive impact of healthy heart gymnastics on physical fitness athletes of the city of Padang. Method: Types of a quasi research experiment. The population will be immediately sampled in this study, namely the weightlifters of Padang city which amounted to 18 people. Inst ruments using the TKJI test before and after given healthy heart gymnastics treatment. Data were analyzed using parametric statistics through test ״t״ formula at a significance of 0.05 α. Results: Based on the results of the research analysis was concluded that there is a significant increase in physical fitness, Mean difference (difference in calculating average) = 4.78, T count = 13,719 > this = 2,120. Meaning healthy Heart Gymnastics provides meaningful influence on the improvement of the physical fitne ss of the Padang city weightlifters.
从现象和教练员报告的举重训练方案来看,举重运动员更多的是以重量训练的形式进行增加肌肉力量的练习。在训练计划中实施隐形运动员体能训练或健身训练。因此,举重运动员的身体新鲜度在一个不太好的类别(不够好的S/d)。目的:研究巴东市健美操对健美操运动员体能的影响。方法:采用准研究型实验。在这项研究中,人口将立即抽样,即巴东市的举重运动员,共计18人。器械使用TKJI测试前后给予健康心脏体操治疗。对数据进行参数统计,采用“测试”公式,显著性为0.05 α。结果:根据研究结果分析得出体质有明显提高,Mean difference(计算平均值的差异)= 4.78,T计数= 13,719 > = 2,120。意义健心体操对巴东市举重运动员体质的提高具有重要意义。
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引用次数: 0
Determination of some bone markers, minerals during toxoplasmosis in women in Kirkuk Province 基尔库克省妇女弓形虫病期间一些骨标记物和矿物质的测定
Pub Date : 2021-02-01 DOI: 10.36295/ASRO.2021.24236
F. Noori, S. Hussien, Faten Ayoob Tayeeb, Y. Salman
Toxoplasmosis is a global disease, caused by a protozoan parasite called Toxoplasma gondii. About onethird of people are born with anti-Toxoplasma antibodies worldwide. The deficiency of minerals and some bone markers had a strong impact on getting infectious diseases. The main aims involve: to assess the incidence of Toxoplasma gondii antibodies in sera of women and to check any changes in the level of some minerals and bone markers. a total of 183 sera and 45 sera in test and control groups, respectively were tested for Toxoplasma antibodies using ELISA and spectrophotometry for determining minerals. All rates of toxoplasmosis were 41.53% contributed 24.59% for Toxo-IgG antibodies and 16.94 % for IgM. The relationship between seropositive toxoplasmosis and women's age was significant, p<0.05. The rate of toxoplasmosis in sera of women from the urban area was higher than those in the rural area, p<0.05.The vitamin D deficiency rate was 63.93 % among women in relation to toxoplasmosis and the high rate of deficiency was recorded among women aging from 26 to 35 years. Relationship between Toxoplasma positivity, calcium, vitamin D deficiency with women age was significant. Hypermagnesemia and hyper-zincemia during toxoplasmosis were higher compared to those in the control group, P<0.05. Furthermore statistically S. Copper during toxoplasmosis was higher compared to those in the control group. Serum Vitamin D deficiency, calcium, and magnesium mean levels in considering to Toxoplasma picture (acute, chronic and subacute) were significant. The relationship between seropositive toxoplasmosis with, vitamin D disorder, minerals, and bone markers was significant.
弓形虫病是一种全球性疾病,由一种叫做刚地弓形虫的原生动物寄生虫引起。全世界约有三分之一的人天生具有抗弓形虫抗体。矿物质和一些骨标记物的缺乏对感染传染病有很大的影响。主要目的包括:评估妇女血清中弓形虫抗体的发生率,并检查某些矿物质和骨标记物水平的变化。采用ELISA法和分光光度法测定矿物质,分别对试验组183份血清和对照组45份血清进行弓形虫抗体检测。弓形虫病阳性率为41.53%,其中弓形虫igg抗体阳性率为24.59%,IgM抗体阳性率为16.94%。血清弓形虫病阳性与女性年龄有显著关系,p<0.05。城区妇女血清弓形虫病检出率高于农村,差异有统计学意义(p<0.05)。与弓形虫病有关的妇女维生素D缺乏率为63.93%,其中26 ~ 35岁妇女缺乏率最高。弓形虫阳性、钙、维生素D缺乏与女性年龄有显著关系。弓形虫病期间高镁血症和高锌血症高于对照组,P<0.05。此外,统计上S.铜在弓形虫病期间高于对照组。血清维生素D缺乏,钙和镁的平均水平考虑弓形虫图像(急性,慢性和亚急性)显著。血清弓形虫病阳性与维生素D紊乱、矿物质和骨标志物之间的关系是显著的。
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引用次数: 2
Potential role of toxoplasmosis to change interleukin 12 level in leukemia patients 弓形虫病改变白血病患者白细胞介素12水平的潜在作用
Pub Date : 2021-02-01 DOI: 10.36295/ASRO.2021.24221
Albatool Salim Mkhaiber, E. Saheb
Toxoplasma gondii is an opportunistic pathogen in which the reactivation of a dormant infection can cause death in immunocompromised patients. The goal of this study is to investigate the possible risk-factor of Toxoplasma infection and its possible correlation with Interleukin-12 (IL-12) cytokine in leukemia patients and according the leukemia types. In this study, 185 patients were enrolled. All serum samples were tested by using enzyme-linked immunosorbent assay (ELISA) technique for the measurement of antiToxoplasma (IgG, IgM) antibodies and IL-12 levels. The serological examination revealed that 63 (51.2%) leukemia patients were positive to antiToxoplasma IgG compared with the sera of the control group which was 48 (77.4%). Their positivity rates for antiToxoplasma IgM in leukemia patients was 3 (2.4%) while it was 2 (3.23%) in the control group. . The mean level of IL-12 in leukemia patients infected with toxoplasmosis was the significant 188.865 ±2.845 pg/ml,being higher than the mean value in the positive control which was 85.330±2.834pg/ml.Furthermore, the seroprevalence of antiToxoplasma IgG was the highest in the age group (4150) years in patients with leukemia. There were no significant differences between age and leukemia patients infected with toxoplasmosis. Since most immunosuppressive patients are exposed to various possible risk factors including Toxoplasma, primary infection or reactivation, so it is important to diagnose and treat toxoplasmosis in leukemia patients to reduce the consequences of this infection.
刚地弓形虫是一种机会性病原体,其中休眠感染的重新激活可导致免疫功能低下患者死亡。本研究的目的是探讨弓形虫感染的可能危险因素及其与白细胞介素-12 (IL-12)细胞因子在白血病患者和白血病类型中的可能相关性。在这项研究中,185名患者入组。采用酶联免疫吸附试验(ELISA)检测血清中抗弓形虫(IgG、IgM)抗体和IL-12水平。血清学检查结果显示,白血病患者血清抗弓形虫IgG阳性63例(51.2%),对照组阳性48例(77.4%)。白血病患者抗弓形虫IgM阳性3例(2.4%),对照组阳性2例(3.23%)。白血病弓形虫感染患者IL-12平均水平为188.865±2.845 pg/ml,高于阳性对照组的85.330±2.834pg/ml。此外,抗弓形虫IgG血清阳性率在4150岁的白血病患者中最高。白血病患者感染弓形虫病的年龄差异无统计学意义。由于大多数免疫抑制患者暴露于各种可能的危险因素,包括弓形虫、原发感染或再激活,因此诊断和治疗白血病患者弓形虫病以减少这种感染的后果非常重要。
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Annals of Tropical Medicine and Public Health
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