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A Risk Assessment Approach for Nursing Infants Exposed to Volatile Organics through the Mother's Occupational Inhalation Exposure 通过母亲职业吸入暴露于挥发性有机物的哺乳婴儿的风险评估方法
Pub Date : 1989-01-01 DOI: 10.1080/08828032.1989.10389886
M. L. Shelley, M. Andersen, J. Fisher
Abstract A “rule-of-thumb” methodology is presented to assist in assessing risk to a nursing child due to the mother's occupational inhalation exposure. The method represents an example of the use of physiologically-based pharmacokinetic modeling using state-of-the-art computational techniques. A computer model is developed to describe distribution of nonmetabolized, inhaled contaminants into a mother/child system as a function of the contaminant's blood: air and octanol: water partition coefficients. Effective dose is calculated in terms of the area under the blood concentration vs. time curve of the exposure chemical. Since low partition values yield low risk for the nursing child and high values yield high risk, the model is exercised over a range of intermediate values (blood: air = [2, 25]; octanol: water = [100, 1500]). Results are thus applicable to chemicals for which the mother's dose is a strong factor in estimating the child's risk. The most notable observation is that, for the range of partiti...
摘要:一个“经验法则”的方法提出,以协助评估风险,以哺乳儿童由于母亲的职业吸入暴露。该方法代表了使用最先进的计算技术使用基于生理的药代动力学建模的一个例子。开发了一个计算机模型来描述非代谢的,吸入污染物在母亲/儿童系统中的分布,作为污染物的血液:空气和辛醇:水分配系数的函数。有效剂量是根据暴露化学品的血浓度与时间曲线下的面积来计算的。由于低分割值对哺乳儿童的风险较低,高分割值则风险较高,因此模型在中间值范围内运行(血液:空气= [2,25];辛醇:水=[100,1500])。因此,研究结果适用于母亲的剂量是估计儿童风险的重要因素的化学品。最值得注意的观察是,对于partiti的范围…
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引用次数: 12
Occupational Health Data Analysis 职业卫生数据分析
Pub Date : 1989-01-01 DOI: 10.1080/08828032.1989.10389870
T. Owens
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引用次数: 0
Indoor/Outdoor Air Quality: Reference Pollutant Concentrations in Complaint-Free Residences 室内/室外空气质量:无投诉住宅参考污染物浓度
Pub Date : 1989-01-01 DOI: 10.1080/08828032.1989.10389885
Dorothy D. Montgomery, D. Kalman
Abstract The intent of this study was to determine baseline air pollutant concentrations present in indoor environments in which occupants did not exhibit “sick building” symptoms. To accomplish this task, concentrations of particulate matter, formaldehyde, carbon monoxide, carbon dioxide, and volatile organic compounds (VOCs) were determined at 17 residences in Ruston, Washington. All measurements were made inside and outside each home simultaneously, utilizing sampling techniques common within industrial hygiene, including impinger, Teflon® filter, air bag, and charcoal tube. Samples were analyzed using gravimetric and colorimeteric techniques, gas chromatography, gas chromatography/mass spectrophotometry, and infrared spectrophotometry. Four different space heating systems were represented within the set of homes, and each home was sampled during late summer and fall/winter. Observations from this study support previous research in illustrating that the indoor low contaminant level residential environm...
摘要本研究的目的是确定室内环境中存在的基线空气污染物浓度,其中居住者没有表现出“病态建筑”症状。为了完成这项任务,在华盛顿州拉斯顿的17个住宅中测定了颗粒物、甲醛、一氧化碳、二氧化碳和挥发性有机化合物(VOCs)的浓度。所有测量都是在每个家庭内外同时进行的,使用工业卫生中常见的采样技术,包括撞击器、特氟龙®过滤器、气囊和木炭管。样品分析使用重量和比色技术,气相色谱法,气相色谱/质分光光度法和红外分光光度法。在一组家庭中代表了四种不同的空间供暖系统,每个家庭在夏末和秋冬取样。本研究的观察结果支持了先前的研究,说明室内低污染水平的居住环境…
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引用次数: 40
Ventilation to Eliminate Oxygen Deficiency in a Confined Space—Part II: Noncubical Models 消除密闭空间缺氧的通风——第二部分:非立方体模型
Pub Date : 1989-01-01 DOI: 10.1080/08828032.1989.10388588
R. Garrison, Muzaffer Erig
Abstract This study investigated characteristics of ventilation to eliminate oxygen deficiency for confined space (CS) models having several noncubical shapes. Variations from a basic cubical shape (studied previously) included sideways expansion (normal to the vertical ventilation axis), depthwise expansion (parallel to the ventilation axis), and expansions in more than one direction. Variable design parameters, in addition to shape, included ventilation mode (exhaust and supply), volume flow rate, inlet/outlet elevation, and location inside the CS model. Regressions of the experimental data supplement a database from previous studies of a cubical model. The oxygen recovery data can be used to calculate ventilation times, subject to consideration of limitations which apply to the results. The findings also suggest general guidelines for CS ventilation design. Progressive sideways and depthwise expansions produced progressive increases in ventilation time for oxygen recovery. This variation was consistent...
摘要:本研究探讨了具有几种非立方体形状的密闭空间(CS)模型的通风特性,以消除缺氧。从基本立方体形状(以前研究过)的变化包括侧向膨胀(垂直于垂直通风轴),深度膨胀(平行于通风轴),以及在多个方向上的膨胀。可变的设计参数,除了形状,包括通风模式(排气和供应),体积流量,入口/出口标高,和位置内的CS模型。实验数据的回归补充了先前立方体模型研究的数据库。氧气回收数据可用于计算通风时间,但要考虑适用于结果的限制。研究结果还提出了CS通风设计的一般准则。渐进式向侧和深度扩张导致氧气恢复的通气时间渐进式增加。这种变化是一致的……
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引用次数: 5
Correlation of Tests for Material Dustiness with Worker Exposure from the Bagging of Powders 粉末装袋过程中工人暴露与物料粉尘试验的相关性
Pub Date : 1989-01-01 DOI: 10.1080/08828032.1989.10389884
W. Heitbrink, W. F. Todd, T. Fischbach
Abstract A significant correlation was found between worker dust exposure from a bag packing operation and the results of two dustiness testers. The dustiness testers were the Heubach Dust Measurement Appliance and the Midwest Research Institute (MRI) Dustiness Tester. Both the Heubach and MRI dustiness tester predicted dust exposures to within an order of magnitude for the operation studied. The width of the prediction interval reflects typical variability in worker dust exposure measurements. Although the correlation between dustiness test results and dust exposures may be different for other operations, these results suggest that dustiness tests can be used to compare the relative potential of different materials to cause dust exposures. Heitbrink, W.A.; Todd, W.F.; Fischbach, T.J.: Correlation of Tests for Material Dustiness with Worker Exposure from the Bagging of Powders. Appl. Ind. Hyg. 4:12–16; 1989.
摘要:研究了袋装作业工人粉尘暴露与两项粉尘测试结果之间的显著相关性。粉尘测试仪是休巴赫粉尘测量仪和中西部研究所(MRI)粉尘测试仪。休巴赫和核磁共振尘埃测试仪都预测了所研究手术的粉尘暴露在一个数量级内。预测区间的宽度反映了工人粉尘暴露测量的典型可变性。虽然粉尘测试结果与粉尘暴露之间的相关性可能因其他操作而异,但这些结果表明,粉尘测试可用于比较不同材料引起粉尘暴露的相对可能性。西澳Heitbrink;托德,W.F.;材料粉尘测试与工人从粉末装袋暴露的相关性。达成。启4:12-16;1989.
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引用次数: 17
Capture Efficiency of Flanged Slot Hoods under the Influence of a Uniform Cross Draft: Model Development and Validation 均匀交叉气流影响下的法兰槽罩捕集效率:模型开发与验证
Pub Date : 1989-01-01 DOI: 10.1080/08828032.1989.10390399
L. Conroy, M. Ellenbecker
Abstract Capture velocity is the primary design parameter now used for slot hoods. However, capture velocity has an uncertain relationship with the true variable of interest, capture efficiency, the fraction of contaminant generated which is captured directly by the hood. Using the three-dimensional velocity field developed from potential flow theory, and including an arbitrary cross draft term, a model was developed that predicts the dividing velocity streamline in front of a slot hood. The location of this streamline, together with an empirical factor accounting for turbulent diffusion of contaminant around streamlines, are the parameters needed to determine capture efficiency. Wind tunnel experiments to validate the model consisted of measuring the fraction of a tracer gas captured by six different hoods under various face and cross draft velocity conditions. The measured capture efficiencies are compared directly with predictions, and errors less than 20 percent are observed for most values of capture...
捕获速度是现在用于槽罩的主要设计参数。然而,捕获速度与真正感兴趣的变量,捕获效率,产生的污染物直接被罩捕获的比例有不确定的关系。利用位流理论建立的三维速度场,考虑任意交叉牵引力项,建立了槽式罩前分速流线的预测模型。这条流线的位置,以及考虑污染物在流线周围湍流扩散的经验因素,是确定捕获效率所需的参数。为了验证该模型,风洞实验包括在不同的面和横向气流速度条件下测量六个不同罩捕获的示踪气体的比例。测量的捕获效率与预测结果直接比较,大多数捕获值的误差小于20%。
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引用次数: 9
Industrial Hygiene Programs Management, VIII: Preliminary Industrial Hygiene Survey Program 工业卫生规划管理,VIII:工业卫生初步调查规划
Pub Date : 1989-01-01 DOI: 10.1080/08828032.1989.10389869
K. Still, B. Wells
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引用次数: 0
IV News Digest: Current Topics in Industrial Ventilation 新闻文摘:工业通风的当前主题
Pub Date : 1989-01-01 DOI: 10.1080/08828032.1988.10388495
D. J. Burton
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引用次数: 0
IH Interface: Right Writer: Recognize, Evaluate, and Control Writing Hazards 接口:正确的作者:识别,评估和控制写作危害
Pub Date : 1989-01-01 DOI: 10.1080/08828032.1989.10389868
L. Wilcox
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引用次数: 0
Energy Expenditure Modeling in the Return-to-Work Decision Process 回归工作决策过程中的能量消耗模型
Pub Date : 1988-12-01 DOI: 10.1080/08828032.1988.10390346
G. Caple
Abstract With the current trend in industry to reduce unnecessary expenses, the involvement of the industrial hygienist in the scheme of risk management services is growing. One aspect of risk management in which the industrial hygienist may become involved is the employee return-to-work (RTW) program following an injury or illness. Whether or not the illness or injury is occupational in nature, an expeditious return to work is a direct dollar savings tool. Generally, the physician's decision to return an employee to the job is based solely on information gained from the employee alone. This information is gained from an untrained observer and is subject to positive or negative bias. Intervention by the industrial hygienist armed with factual information may facilitate the early return to work of the employee. Energy expenditure modeling is a technique which can provide the physician with an assessment of the metabolic demands of the job. The modeled information may be compared to a Maximum Aerobic Power ...
随着当前工业中减少不必要费用的趋势,工业卫生学家在风险管理服务方案中的参与越来越多。工业卫生学家可能涉及的风险管理的一个方面是员工在受伤或生病后重返工作岗位(RTW)计划。无论疾病或伤害是否是职业性的,迅速返回工作岗位是一个直接的节省美元的工具。一般来说,医生决定让雇员重返工作岗位完全是基于从雇员那里获得的信息。这些信息是从未经训练的观察者那里获得的,并受到积极或消极偏见的影响。工业卫生学家掌握事实信息的干预可能有助于雇员早日重返工作岗位。能量消耗模型是一种可以为医生提供工作代谢需求评估的技术。模型信息可以与最大有氧能力进行比较。
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引用次数: 1
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Applied Industrial Hygiene
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