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Robust measure of ST/HR hysteresis in stress test ECG recordings 应力测试心电图记录中ST/HR迟滞的鲁棒测量
Pub Date : 2002-09-22 DOI: 10.1109/CIC.2002.1166775
R. Bailón, S. Olmos, P. Serrano, J. García, P. Laguna
In stress test ECG analysis, the so-called ST/HR hysteresis has recently been suggested to improve coronary artery disease (CAD) diagnosis. This parameter is estimated from the ST versus HR diagram including exercise and recovery phases. Unluckily, ST measurements are adversely affected by noise during the test. In this study we propose a method to automatically estimate the ST/HR hysteresis, incorporating multiple stage noise attenuation. The method is based on averaging and rejection of noisy beats. Evaluation is done on simulated exercise test recordings, constructed from real ECG averaged beats adding actual noise from stress test records. Results on a total of 216 different records, with RMS noise levels ranging from 114 to 979 /spl mu/V, give a reduction in estimation error in the ST/HR diagram of 77.98% (from 168 to 37 /spl mu/V) in mean and of 76.38% (from 271 to 63 /spl mu/V) in standard deviation. This method may be considered as a suitable and robust tool for reliable ST/HR hysteresis estimation.
在压力测试心电图分析中,所谓的ST/HR迟滞最近被建议用于改善冠状动脉疾病(CAD)的诊断。这个参数是从包括运动和恢复阶段的ST与HR图中估计出来的。不幸的是,测试期间的ST测量受到噪声的不利影响。在这项研究中,我们提出了一种自动估计ST/HR滞后的方法,并结合了多级噪声衰减。该方法基于噪声节拍的平均和抑制。对模拟运动测试记录进行评估,该记录由真实的心电平均心跳和压力测试记录的实际噪声组成。结果表明,在RMS噪声水平范围为114 - 979 /spl mu/V的216条不同记录上,ST/HR图的估计误差平均降低77.98%(从168 - 37 /spl mu/V),标准差降低76.38%(从271 - 63 /spl mu/V)。该方法可被认为是一种可靠的ST/HR滞后估计的合适且稳健的工具。
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引用次数: 13
Analysis of the respiratory and cardiac systems coupling in pyramidal exercise using a time-varying model 用时变模型分析锥体运动中呼吸和心脏系统的耦合
Pub Date : 2002-09-22 DOI: 10.1109/CIC.2002.1166801
Olivier Meste, G. Blain, S. Bermon
The analysis of heart period series is a difficult task especially under graded exercise conditions. Among all the information present in these series, we are more interested in the coupling between respiratory and cardiac systems, known as respiratory sinus arrythmia. We show in this work that from the heart period series precise patterns concerning the respiratory frequency can be extracted. Evolutive model is introduced in order to achieve the tracking of the main frequencies and their time-varying power.
心脏周期序列的分析是一项艰巨的任务,特别是在分级运动条件下。在这些系列中提供的所有信息中,我们对呼吸和心脏系统之间的耦合更感兴趣,称为呼吸性窦性心律失常。我们在这项工作中表明,可以从心脏周期序列中提取有关呼吸频率的精确模式。为了实现对主频率及其时变功率的跟踪,引入了进化模型。
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引用次数: 12
The simulation study of the influence of electrical asynchrony on regional mechanics of the ischemic ventricle using electromechanical heart models 电不同步对缺血心室局部力学影响的机电心脏模型模拟研究
Pub Date : 2002-09-22 DOI: 10.1109/CIC.2002.1166820
L. Xia, M. Huo, F. Liu
Using mathematical modeling method, this paper investigates the interactions between electrical conduction and mechanical function in the ischemia or infarcted ventricle. The influence of electrical asynchrony on regional mechanics of the ventricle is simulated based on electromechanical heart models. Regional deformation, strain and stress are calculated during systole phase. The preliminary results show that considerable disruption of the contraction pattern occurs in the near ischemic zone, the minimum principal strains in local infarction regions were significantly smaller than those in corresponding regions of the normal heart, while the stresses are larger than those of normal tissues. The simulated results are compared with dog experiments and solutions obtained in the literature. This simulation suggests that such coupled heart models can be used to assess the mechanical function of the ventricle with diseases such as myocardial ischemic or infarction.
本文采用数学建模的方法,研究了缺血或梗死心室的电传导和机械功能之间的相互作用。基于机电心脏模型,模拟了电非同步对心室局部力学的影响。收缩阶段计算区域变形、应变和应力。初步结果表明,心肌缺血区收缩模式发生明显破坏,局部梗死区最小主应变明显小于正常心肌相应区域,而应力则大于正常心肌组织。模拟结果与狗实验和文献中得到的解进行了比较。这一模拟表明,这种耦合心脏模型可用于评估患有心肌缺血或梗死等疾病的心室的机械功能。
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引用次数: 0
Early detection of essential hypertension by time-frequency analysis 时频分析早期发现原发性高血压
Pub Date : 2002-09-22 DOI: 10.1109/CIC.2002.1166805
L. R. Davrath, Y. Goren, I. Pinhas, D. David, S. Akselrod
Hypertension affects approximately 25% of adults in industrialized countries and contributes significantly to morbidity and mortality from cardiovascular diseases. Young adult, normotensive offspring of one hypertensive parent (KHT, n = 12) and normotensive offspring of two normotensive parents (YN, n = 14) participated ECG, continuous blood pressure, and respiration were recorded Time-frequency decomposition of these signals was performed by a Continuous Wavelet Transform. During change in posture (CP), KHT demonstrated a significantly greater increase in the low frequency fluctuations in heart rate (HR) than YN, indicating enhanced sympathetic involvement in the HR response to CP. Upon recovery from Handgrip, vagal reactivation was more sluggish in KHT These results indicate possible malfunctions in both branches of autonomic control in individuals at increased risk of hypertension.
在工业化国家,高血压影响约25%的成年人,是心血管疾病发病率和死亡率的重要因素。记录年轻成人、双亲中一人血压正常的后代(KHT, n = 12)和双亲中一人血压正常的后代(YN, n = 14)的心电图、连续血压和呼吸信号,采用连续小波变换对这些信号进行时频分解。在体位改变(CP)过程中,KHT表现出比YN更大的低频心率波动(HR)增加,表明交感神经参与对CP的HR反应增强。从握力恢复后,KHT的迷走神经再激活更缓慢,这些结果表明高血压风险增加的个体自主控制的两个分支可能出现故障。
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引用次数: 0
Comparison of atrial rhythm extraction techniques for the estimation of the main atrial frequency from the 12-lead electrocardiogram in atrial fibrillation 从12导联心电图估计心房颤动主频率的心房节律提取技术的比较
Pub Date : 2002-09-22 DOI: 10.1109/CIC.2002.1166699
P. Langley, M. Stridh, J. J. Rieta, L. Sornmo, J. Millet-Roig, A. Murray
One of the greatest challenges in analysis of the atrial rhythm from the ECG is to distinguish the atrial component from the large ventricular components. Our aim was to compare three techniques of atrial rhythm extraction from three groups working on this problem. 12-lead ECG data from 7 patients in atrial fibrillation were analysed. For extraction of the atrial rhythm, spatiotemporal QRST cancellation was performed by the Lund group, blind source separation by the Valencia group, and principal component analysis by the Newcastle group. Peak atrial frequency was determined by Fourier transform of the signal with the largest atrial activity. All algorithms were successful in distinguishing the atrial rhythm from the low frequency ventricular rhythm. The mean (range) atrial frequency was 6.5 (5.9 7.6) Hz (Lund), 6.7 (5.7 - 7.9) Hz (Valencia) and 6.5 (5.9 - 8.2) Hz (Newcastle). There were no significant differences between the atrial frequencies estimated by each of the techniques.
从心电图分析心房节律的最大挑战之一是区分心房成分和大心室成分。我们的目的是比较三组在这个问题上工作的心房节律提取的三种技术。对7例房颤患者的12导联心电图资料进行分析。对于心房节律的提取,Lund组进行时空QRST对消,Valencia组进行盲源分离,Newcastle组进行主成分分析。通过心房活动最大的信号的傅里叶变换确定心房频率峰值。所有算法都能成功地区分心房节律和低频心室节律。平均(范围)心房频率为6.5 (5.9 - 7.6)Hz(隆德),6.7 (5.7 - 7.9)Hz(瓦伦西亚)和6.5 (5.9 - 8.2)Hz(纽卡斯尔)。每一种技术估计的心房频率之间没有显著差异。
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引用次数: 27
Cardiovascular response to sinusoidal neck suction in healthy volunteers and orthostatic intolerance patients 健康志愿者和直立性不耐受患者对颈部正弦吸痰的心血管反应
Pub Date : 2002-09-22 DOI: 10.1109/CIC.2002.1166702
L. Widesott, L. Bernardi, R. Furlan, L. Diedrich, R. Antolini, G. Nollo, A. Diedrich
The dynamic response to sinusoidal neck suction, of the RR interval, systolic arterial blood pressure and muscle sympathetic nerve activity series, was studied in 10 controls and 5 patients with orthostatic intolerance. By using different spectral techniques (autoregressive, short time Fourier transformation), the cardiovascular and MSNA variability were analyzed during 0.1 Hz and 0.2 Hz frequency of neck suction. Moreover, by using the autoregressive model, a quantitative analysis of particular power spectral frequency bands was done. Finally, a chirp neck suction input signal was applied to qualitatively compare the frequency response. The patients with orthostatic intolerance showed a partial blood pressure response to NS, particularly over 0.1 Hz compared to controls.
本文研究了10例对照和5例直立性不耐受患者对正弦颈吸的动态反应,包括RR间期、收缩压和肌肉交感神经活动系列。采用不同的频谱技术(自回归、短时傅立叶变换),分析0.1 Hz和0.2 Hz吸颈频率下心血管和MSNA的变异性。此外,利用自回归模型对特定功率谱频段进行了定量分析。最后,采用啁啾颈吸输入信号对频率响应进行定性比较。与对照组相比,直立不耐受患者对NS有部分血压反应,特别是在0.1 Hz以上。
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引用次数: 0
Volumetric coronary plaque composition using intravascular ultrasound: three-dimensional segmentation and spectral analysis 血管内超声测量冠状动脉斑块组成:三维分割和光谱分析
Pub Date : 2002-09-22 DOI: 10.1109/CIC.2002.1166720
J. Klingensmith, A. Nair, B. Kuban, D. Vince
Intravascular ultrasound provides precise tomographic assessment of coronary artery disease, allowing unique potential for analysis of both plaque geometry and composition, two critical factors related to the likelihood of plaque rupture. A novel three-dimensional segmentation technique and spectral analysis are used to create a unique tool for volumetric assessment of plaque composition. The semi-automated 3D segmentation technique was used to identify luminal and medial-adventitial borders in ECG-gated images created from radiofrequency (RF) IVUS data acquired during automated pullbacks in patients. Spectral analysis was applied to the RF data within the segmented plaque. Color-coded pseudo-histology images were created from these plaque component predictions using statistical classification trees. Quantitative analysis and visualization techniques were used to assess volumetric plaque composition and provide a unique tool for evaluation of plaque vulnerability.
血管内超声提供了冠状动脉疾病的精确断层扫描评估,允许分析斑块几何形状和组成的独特潜力,这两个关键因素与斑块破裂的可能性有关。一种新的三维分割技术和光谱分析被用来创建一个独特的工具,用于斑块组成的体积评估。半自动3D分割技术用于识别患者自动回拉过程中射频(RF) IVUS数据生成的ecg门控图像中的腔内和中外边界。频谱分析应用于分割斑块内的射频数据。使用统计分类树从这些斑块成分预测中创建颜色编码的伪组织学图像。定量分析和可视化技术用于评估斑块的体积组成,并为评估斑块易损性提供了独特的工具。
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引用次数: 2
A signals and systems and object oriented programming approach to development of ECG analysis software 采用信号与系统和面向对象编程的方法开发心电分析软件
Pub Date : 2002-09-22 DOI: 10.1109/CIC.2002.1166730
S. Mohammad, A. Sureka, D.R. Ely, J. Jenkins
A Visual Software Development Framework (VSDF) has been created to facilitate the software coding process of biological signal analysis. A special purpose graphical user interface (GUI) was developed using VSDF for automating the analysis and classification of waveforms in electrocardiographic (ECG) data. Graphing capabilities were included in the program to allow the user to plot the signal as well as trigger location. Object Oriented Programming (OOP) techniques were used in the Java programming language to calculate correlation coefficients between a template QRS complex and detected QRS complexes throughout an ECG recording. The OOP techniques employed in the development of the software package allow visualization of the entire analysis process. The ECG signal, read from a file, is stored into a simple array data structure and is passed to each of the modules. The signals and systems approach allows incorporation of trigger modules, data conversion modules, and numerical analysis modules directly into the software package, providing ease of software design.
一个可视化软件开发框架(VSDF)已被创建,以方便生物信号分析的软件编码过程。利用VSDF开发了一种特殊用途的图形用户界面(GUI),用于自动分析和分类心电图(ECG)数据中的波形。绘图功能包括在程序中,允许用户绘制信号以及触发位置。在Java编程语言中使用面向对象编程(OOP)技术计算整个心电记录过程中模板QRS复合物与检测QRS复合物之间的相关系数。在软件包开发中使用的面向对象技术允许整个分析过程的可视化。从文件中读取的心电信号被存储到一个简单的数组数据结构中,并传递给每个模块。信号和系统方法允许将触发模块,数据转换模块和数值分析模块直接合并到软件包中,从而简化了软件设计。
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引用次数: 0
Are nonlinear ventricular arrhythmia characteristics lost, as signal duration decreases? 随着信号持续时间的减少,非线性室性心律失常特征是否消失?
Pub Date : 2002-09-22 DOI: 10.1109/CIC.2002.1166747
R. Povinelli, F. M. Roberts, Michael T. Johnson, K. Ropella
A novel, nonlinear, phase space based method to quickly and accurately identify life-threatening arrhythmias is proposed. The accuracy of the proposed method in identifying sinus rhythm (SR), monomorphic ventricular tachycardia (MVT), polymorphic VT (PVT), and ventricular fibrillation (VF) for signals of at least 0.5 s duration was determined for six different ECG signal lengths. The ECG recordings were transformed into a phase space, and statistical features of the resulting attractors were learned using artificial neural networks. Classification accuracies for SR, MVT, PVT and VF were 93-96, 95-100, 79-91, and 81-88%, respectively. As expected, classification accuracy for the proposed method was essentially equivalent for ECG signals longer than 1 s. Surprisingly, classification accuracy for this new method did not degrade for 0.5 s ECG signals, indicating that even such short duration signals contain structures predictive of rhythm type. The phase space method's classification accuracy was higher for all segment durations compared to two other methods.
提出了一种新的、非线性的、基于相空间的快速准确识别危及生命的心律失常的方法。在6种不同的心电信号长度下,对持续时间至少为0.5 s的信号,确定该方法识别窦性心律(SR)、单形态室性心动过速(MVT)、多形态室性心动过速(PVT)和心室颤动(VF)的准确性。将心电记录转换成相空间,利用人工神经网络学习吸引子的统计特征。SR、MVT、PVT和VF的分类准确率分别为93 ~ 96、95 ~ 100、79 ~ 91和81 ~ 88%。正如预期的那样,对于超过1秒的心电信号,该方法的分类精度基本相同。令人惊讶的是,这种新方法的分类精度在0.5 s的ECG信号中没有下降,这表明即使是如此短的持续时间信号也包含预测节律类型的结构。相空间法在所有分段持续时间内的分类精度均高于其他两种方法。
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引用次数: 20
Optimal myocardial boundary estimation for MR cardio perfusion measurements using sensitivity analysis 最佳心肌边界估计磁共振心脏灌注测量使用敏感性分析
Pub Date : 2002-09-22 DOI: 10.1109/CIC.2002.1166741
L. Spreeuwers, F. Wierda, M. Breeuwer
Recent advances in Magnetic Resonance Imaging allow fast recording of contrast enhanced myocardial perfusion scans. MR perfusion scans are made by recording, during a period of 20-40 seconds a number of short-axis slices through the myocardium. For perfusion analysis, the myocardial boundaries must be traced, dividing the heart into the left and right ventricle blood volumes and the myocardium of the left ventricle. Extreme care must be taken not to include any part of the left or right ventricle blood volumes in the myocardium segment, because this has a significant effect on the perfusion analysis. On the other hand, for accurate estimation of the perfusion parameters, all available myocardium area in the image is required. In this paper a method is proposed to correct for any inclusion of left and right ventricle and optimally place the myocardial contours.
磁共振成像的最新进展允许快速记录造影剂增强心肌灌注扫描。MR灌注扫描是在20-40秒的时间内通过心肌记录一些短轴切片。在进行灌注分析时,必须描出心肌边界,将心脏分为左、右心室血容量和左心室心肌。必须特别注意不要将左、右心室血容量的任何部分包括在心肌段,因为这对灌注分析有重大影响。另一方面,为了准确估计灌注参数,需要图像中所有可用的心肌面积。本文提出了一种校正左、右心室的方法,并对心肌轮廓进行了优化定位。
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引用次数: 6
期刊
Computers in cardiology
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