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Investigation of the source space of electrocardiography and magnetocardiography using isotropic and anisotropic thorax models 各向同性和各向异性胸腔模型的心电图和心磁图源空间研究
Pub Date : 2002-09-22 DOI: 10.1109/CIC.2002.1166819
M. Nalbach, O. Skipa, F. Sachse, O. Dossel
Noninvasive Imaging of the bioelectric processes on the heart using Electrocardiography (ECG) and Magnetocardiography (MCG) data is a widely discussed research topic of the recent years. The source space of ECG is compared with the source space of MCG and vice versa to investigate the difference of information content of these mapping techniques for source imaging purposes. The approach allows the calculation of the intersection and non-intersection part (the calculation of silent sources) of MCG (ECG) in comparison to ECG (MCG). The investigation was carried out on a Finite Element model which was constructed from a magnetic resonance imaging (MRI) dataset of a volunteer. Anisotropic fibre orientation was applied to myocardium to investigate its effect on the differences of the source spaces.
利用心电图(ECG)和心磁图(MCG)数据对心脏的生物电过程进行无创成像是近年来广泛讨论的研究课题。将心电信号的源空间与心电信号的源空间进行对比,并将心电信号的源空间与心电信号的源空间进行对比,探讨两种源成像成像技术在信息含量上的差异。该方法可以计算出与ECG (MCG)相比较的MCG (ECG)的相交部分和非相交部分(无声源的计算)。这项研究是在一个有限元模型上进行的,该模型是由一个志愿者的磁共振成像(MRI)数据集构建的。将各向异性纤维取向应用于心肌,探讨其对心肌源空间差异的影响。
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引用次数: 2
Analysis of the respiratory and cardiac systems coupling in pyramidal exercise using a time-varying model 用时变模型分析锥体运动中呼吸和心脏系统的耦合
Pub Date : 2002-09-22 DOI: 10.1109/CIC.2002.1166801
Olivier Meste, G. Blain, S. Bermon
The analysis of heart period series is a difficult task especially under graded exercise conditions. Among all the information present in these series, we are more interested in the coupling between respiratory and cardiac systems, known as respiratory sinus arrythmia. We show in this work that from the heart period series precise patterns concerning the respiratory frequency can be extracted. Evolutive model is introduced in order to achieve the tracking of the main frequencies and their time-varying power.
心脏周期序列的分析是一项艰巨的任务,特别是在分级运动条件下。在这些系列中提供的所有信息中,我们对呼吸和心脏系统之间的耦合更感兴趣,称为呼吸性窦性心律失常。我们在这项工作中表明,可以从心脏周期序列中提取有关呼吸频率的精确模式。为了实现对主频率及其时变功率的跟踪,引入了进化模型。
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引用次数: 12
The simulation study of the influence of electrical asynchrony on regional mechanics of the ischemic ventricle using electromechanical heart models 电不同步对缺血心室局部力学影响的机电心脏模型模拟研究
Pub Date : 2002-09-22 DOI: 10.1109/CIC.2002.1166820
L. Xia, M. Huo, F. Liu
Using mathematical modeling method, this paper investigates the interactions between electrical conduction and mechanical function in the ischemia or infarcted ventricle. The influence of electrical asynchrony on regional mechanics of the ventricle is simulated based on electromechanical heart models. Regional deformation, strain and stress are calculated during systole phase. The preliminary results show that considerable disruption of the contraction pattern occurs in the near ischemic zone, the minimum principal strains in local infarction regions were significantly smaller than those in corresponding regions of the normal heart, while the stresses are larger than those of normal tissues. The simulated results are compared with dog experiments and solutions obtained in the literature. This simulation suggests that such coupled heart models can be used to assess the mechanical function of the ventricle with diseases such as myocardial ischemic or infarction.
本文采用数学建模的方法,研究了缺血或梗死心室的电传导和机械功能之间的相互作用。基于机电心脏模型,模拟了电非同步对心室局部力学的影响。收缩阶段计算区域变形、应变和应力。初步结果表明,心肌缺血区收缩模式发生明显破坏,局部梗死区最小主应变明显小于正常心肌相应区域,而应力则大于正常心肌组织。模拟结果与狗实验和文献中得到的解进行了比较。这一模拟表明,这种耦合心脏模型可用于评估患有心肌缺血或梗死等疾病的心室的机械功能。
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引用次数: 0
Early detection of essential hypertension by time-frequency analysis 时频分析早期发现原发性高血压
Pub Date : 2002-09-22 DOI: 10.1109/CIC.2002.1166805
L. R. Davrath, Y. Goren, I. Pinhas, D. David, S. Akselrod
Hypertension affects approximately 25% of adults in industrialized countries and contributes significantly to morbidity and mortality from cardiovascular diseases. Young adult, normotensive offspring of one hypertensive parent (KHT, n = 12) and normotensive offspring of two normotensive parents (YN, n = 14) participated ECG, continuous blood pressure, and respiration were recorded Time-frequency decomposition of these signals was performed by a Continuous Wavelet Transform. During change in posture (CP), KHT demonstrated a significantly greater increase in the low frequency fluctuations in heart rate (HR) than YN, indicating enhanced sympathetic involvement in the HR response to CP. Upon recovery from Handgrip, vagal reactivation was more sluggish in KHT These results indicate possible malfunctions in both branches of autonomic control in individuals at increased risk of hypertension.
在工业化国家,高血压影响约25%的成年人,是心血管疾病发病率和死亡率的重要因素。记录年轻成人、双亲中一人血压正常的后代(KHT, n = 12)和双亲中一人血压正常的后代(YN, n = 14)的心电图、连续血压和呼吸信号,采用连续小波变换对这些信号进行时频分解。在体位改变(CP)过程中,KHT表现出比YN更大的低频心率波动(HR)增加,表明交感神经参与对CP的HR反应增强。从握力恢复后,KHT的迷走神经再激活更缓慢,这些结果表明高血压风险增加的个体自主控制的两个分支可能出现故障。
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引用次数: 0
Non-invasive assessment of hemodynamics in adolescents with arterial tonometry and Doppler ultrasound during a conventional stress test 在常规的压力测试中,动脉血压计和多普勒超声对青少年血液动力学的无创评估
Pub Date : 2002-09-22 DOI: 10.1109/CIC.2002.1166823
K. Matthys, D. Vanhercke, S. Van Aken, K. De Groote, I. Coomans, P. Verdonck
Aiming to improve early diagnosis of people at cardiovascular risk, we are developing a custom set-up to allow an adequate hemodynamic analysis of heart function and arterial circulation properties, based on non-invasive acquisition of pressure (arterial tonometry) and flow (Doppler ultrasound techniques) waveforms. In an experimental setting 15 healthy volunteers were examined on a custom made supine bicycle. Able to record usable data throughout the bicycle test and automatically analyse derived hemodynamic parameters such as compliance, peripheral resistance, etc., we also applied the set-up in a real clinical environment. This research contributes to a more complete cardiovascular examination without significant additional discomfort for the patient or prolongation of the test protocol.
为了提高心血管风险人群的早期诊断,我们正在开发一种定制设备,基于无创获取压力(动脉血压计)和血流(多普勒超声技术)波形,允许对心脏功能和动脉循环特性进行充分的血液动力学分析。在一个实验环境中,15名健康志愿者在一辆定制的仰卧自行车上接受了检查。能够在整个自行车测试过程中记录可用数据,并自动分析衍生的血流动力学参数,如顺应性,外周阻力等,我们也将该设置应用于真实的临床环境。这项研究有助于更完整的心血管检查,而不会给患者带来明显的额外不适或延长测试方案。
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引用次数: 4
Spectral analysis of multiunit action potential trains of muscle sympathetic nerve activity in humans 人体肌肉交感神经活动多单元动作电位序列的频谱分析
Pub Date : 2002-09-22 DOI: 10.1109/CIC.2002.1166808
R. Brychtal, W. Charoensuk, L. Bernardi, R. Furlan, R. Shiavi, A. Diedrich
The application of conventional signal processing methods used to obtain an integrated signal from muscle sympathetic nerve activity (MSNA) reduces the amount of information and may confound the spectral characteristics. We present a novel alternative method of processing the raw MSNA signal using a wavelet transform denoising technique that enables detection of individual action potentials and facilitates spectral analysis. A spike density function (SDF) is generated from the denoised signal by replacing the detected action potentials with delta functions and convolving with a 3 Hz Gaussian filter. This method was validated using data from a sinusoidal neck suction (NS) experiment in humans. The results of the analysis indicate that the oscillations of sympathetic nerve firings closely followed the NS frequency. In conclusion, the SDF representation allows for a novel and insightful analysis of spectral components of action potential trains in raw MSNA.
传统的信号处理方法用于从肌肉交感神经活动(MSNA)中获得综合信号,减少了信息量,并可能混淆频谱特征。我们提出了一种新的替代方法来处理原始MSNA信号,使用小波变换去噪技术,可以检测单个动作电位并促进频谱分析。用delta函数代替检测到的动作电位,用3hz高斯滤波器卷积,得到去噪信号的峰值密度函数(SDF)。该方法通过人体正弦颈部吸痰(NS)实验数据得到验证。分析结果表明,交感神经放电振荡与NS频率密切相关。总之,SDF表示允许对原始MSNA中动作电位序列的频谱成分进行新颖而深刻的分析。
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引用次数: 4
Detection of central and obstructive sleep apnea in children using pulse transit time 应用脉搏传递时间检测儿童中枢性和阻塞性睡眠呼吸暂停
Pub Date : 2002-09-22 DOI: 10.1109/CIC.2002.1166826
J. Pagani, M. Villa, G. Calcagnini, E. Lombardozzi, F. Censi, S. Poli, P. Bartolini, V. Barbaro, R. Ronchetti
The aim of this study was to validate the use of pulse transit time (PTT) as a method to monitor sleep apnea in children. PTT was estimated as the interval between the ECGR-wave and the point at which the pulse wave at the finger reached 50% amplitude. First, we assessed changes in the PTT during breathing against known resistances in 15 awake children; resistance was applied with a modified nose and mouth two-way nonrebreathing face mask, having the inhalation valve port fitted with drilled plastic cylinders of various diameters. Second, we analyzed 20 events of obstructive apnea and 90 events of central apnea during sleep in 10 children. Our data showed good correlation between the inspiratory effort and PTT oscillation amplitude. In addition, PTT oscillation amplitude tuned out to successfully discriminate central from obstructive apnea.
本研究的目的是验证脉冲传递时间(PTT)作为监测儿童睡眠呼吸暂停的一种方法。PTT估计为ecgr波与手指处脉冲波达到50%振幅点之间的间隔。首先,我们评估了15名清醒儿童在已知阻力下呼吸时PTT的变化;使用改良的口鼻双向非再呼吸面罩施加阻力,吸入阀端口装有不同直径的钻孔塑料圆柱体。其次,我们分析了10名儿童睡眠期间20例阻塞性呼吸暂停事件和90例中枢性呼吸暂停事件。我们的数据显示吸气力与PTT振荡幅度有很好的相关性。此外,PTT振荡振幅调谐成功区分中枢和阻塞性呼吸暂停。
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引用次数: 7
Ubiquitous mobile access to real-time patient monitoring data 无处不在的移动访问实时患者监测数据
Pub Date : 2002-09-22 DOI: 10.1109/CIC.2002.1166833
S. Nelwan, T. B. V. Dam, P. Klootwijk, Simon H. Meij
An application "Pocket WinView" was developed for a Pocket PC personal digital assistant device, which allows remote access to near real-time physiological information from a patient monitor on a commercial handheld device (iPAQ, Pocket PC). The application provides continuous display of up to six monitored physiological waveforms and parameter values. Wireless communication can be established using Wireless LAN and general packet radio service (GPRS). Data is protected with hybrid public key encryption. User authentication is required every time the application is started. Patient data can also be stored on Compact Flash memory cards for data collection purposes. Additional integration with Web-based applications on the hospital intranet make it possible to combine the near realtime signals with previously recorded 12-lead ECGs, laboratory test results, and charting information.
为Pocket PC个人数字助理设备开发了一款名为“Pocket WinView”的应用程序,该应用程序允许远程访问来自商用手持设备(iPAQ, Pocket PC)上的患者监护仪的近实时生理信息。该应用程序提供多达六个监测生理波形和参数值的连续显示。无线通信可以通过无线局域网和通用分组无线业务(GPRS)来实现。数据采用混合公钥加密保护。每次启动应用程序时都需要进行用户身份验证。病人资料亦可储存于紧凑型快闪记忆卡,以作资料收集之用。与医院内部网上基于web的应用程序的额外集成使得将近实时信号与先前记录的12导联心电图、实验室测试结果和图表信息结合起来成为可能。
{"title":"Ubiquitous mobile access to real-time patient monitoring data","authors":"S. Nelwan, T. B. V. Dam, P. Klootwijk, Simon H. Meij","doi":"10.1109/CIC.2002.1166833","DOIUrl":"https://doi.org/10.1109/CIC.2002.1166833","url":null,"abstract":"An application \"Pocket WinView\" was developed for a Pocket PC personal digital assistant device, which allows remote access to near real-time physiological information from a patient monitor on a commercial handheld device (iPAQ, Pocket PC). The application provides continuous display of up to six monitored physiological waveforms and parameter values. Wireless communication can be established using Wireless LAN and general packet radio service (GPRS). Data is protected with hybrid public key encryption. User authentication is required every time the application is started. Patient data can also be stored on Compact Flash memory cards for data collection purposes. Additional integration with Web-based applications on the hospital intranet make it possible to combine the near realtime signals with previously recorded 12-lead ECGs, laboratory test results, and charting information.","PeriodicalId":80984,"journal":{"name":"Computers in cardiology","volume":"1 1","pages":"557-560"},"PeriodicalIF":0.0,"publicationDate":"2002-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/CIC.2002.1166833","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62181787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 60
Beat-to-beat heart rate and QT interval variability in patients undergoing coronary artery bypass graft surgery 冠状动脉搭桥手术患者的单次心率和QT间期变异性
Pub Date : 2002-09-22 DOI: 10.1109/CIC.2002.1166859
S. Frljak, V. Avbelj, R. Trobec, B. Geršak
Non-uniform recovery of myocardial excitability may be essential in triggering malignant ventricular tachycardia in patients after cardiac surgery. Beat-to-beat heart rate and QT interval variability was investigated in 27 patients scheduled for elective coronary artery bypass graft surgery (CABG) and 20 control subjects. 35 channel ECG was recorded for 6 minutes, followed by off line computer analysis. Heart rate interval duration, RR SD, QT SD and power spectra of RR variability were computed from 256-second stable heart rate and QT interval series using MECG software. Study showed that CABG caused increased QT interval variability in face of nearly constant or slowly changing heart rate, suggesting a loss of autonomic coupling between heart rate and ventricular repolarization for sympathovagal modulation.
心肌兴奋性的不均匀恢复可能是引发心脏手术后患者恶性室性心动过速的必要条件。研究了27例计划择期冠状动脉搭桥手术(CABG)患者和20例对照者的次搏动心率和QT间期变异性。记录35通道心电图6分钟,然后进行计算机离线分析。采用MECG软件计算256秒稳定心率和QT间期序列的心率间期持续时间、RR SD、QT SD和RR变异性的功率谱。研究表明,面对几乎恒定或缓慢变化的心率,冠状动脉搭桥导致QT间期变异性增加,提示心率和心室复极之间的自主耦合丧失了交感病理迷走神经调节。
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引用次数: 3
Feasibility of atrial activation time imaging 心房激活时间成像的可行性
Pub Date : 2002-09-22 DOI: 10.1109/CIC.2002.1166844
F. Hanser, B. Tilg, R. Modre, G. Fischer, B. Messnarz, F. Hintringer, F. Roithinger
The feasibility of atrial activation time imaging is investigated based on data sets of four patients who underwent an electrophysiologic study. Several pacing protocols with pacing sites at the right atrial appendage, coronary sinus, and high right atrium were part of the study and were employed to reconstruct the associated atrial activation time patterns. The localization error was estimated to be between 8 and 14 mm.
心房激活时间成像的可行性进行了调查,基于数据集的四个病人谁接受了电生理研究。在右心房附件、冠状动脉窦和右心房高位起搏的几种起搏方案是研究的一部分,并用于重建相关的心房激活时间模式。定位误差估计在8 ~ 14 mm之间。
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引用次数: 2
期刊
Computers in cardiology
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