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Investigation of the source space of electrocardiography and magnetocardiography using isotropic and anisotropic thorax models 各向同性和各向异性胸腔模型的心电图和心磁图源空间研究
Pub Date : 2002-09-22 DOI: 10.1109/CIC.2002.1166819
M. Nalbach, O. Skipa, F. Sachse, O. Dossel
Noninvasive Imaging of the bioelectric processes on the heart using Electrocardiography (ECG) and Magnetocardiography (MCG) data is a widely discussed research topic of the recent years. The source space of ECG is compared with the source space of MCG and vice versa to investigate the difference of information content of these mapping techniques for source imaging purposes. The approach allows the calculation of the intersection and non-intersection part (the calculation of silent sources) of MCG (ECG) in comparison to ECG (MCG). The investigation was carried out on a Finite Element model which was constructed from a magnetic resonance imaging (MRI) dataset of a volunteer. Anisotropic fibre orientation was applied to myocardium to investigate its effect on the differences of the source spaces.
利用心电图(ECG)和心磁图(MCG)数据对心脏的生物电过程进行无创成像是近年来广泛讨论的研究课题。将心电信号的源空间与心电信号的源空间进行对比,并将心电信号的源空间与心电信号的源空间进行对比,探讨两种源成像成像技术在信息含量上的差异。该方法可以计算出与ECG (MCG)相比较的MCG (ECG)的相交部分和非相交部分(无声源的计算)。这项研究是在一个有限元模型上进行的,该模型是由一个志愿者的磁共振成像(MRI)数据集构建的。将各向异性纤维取向应用于心肌,探讨其对心肌源空间差异的影响。
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引用次数: 2
Non-invasive assessment of hemodynamics in adolescents with arterial tonometry and Doppler ultrasound during a conventional stress test 在常规的压力测试中,动脉血压计和多普勒超声对青少年血液动力学的无创评估
Pub Date : 2002-09-22 DOI: 10.1109/CIC.2002.1166823
K. Matthys, D. Vanhercke, S. Van Aken, K. De Groote, I. Coomans, P. Verdonck
Aiming to improve early diagnosis of people at cardiovascular risk, we are developing a custom set-up to allow an adequate hemodynamic analysis of heart function and arterial circulation properties, based on non-invasive acquisition of pressure (arterial tonometry) and flow (Doppler ultrasound techniques) waveforms. In an experimental setting 15 healthy volunteers were examined on a custom made supine bicycle. Able to record usable data throughout the bicycle test and automatically analyse derived hemodynamic parameters such as compliance, peripheral resistance, etc., we also applied the set-up in a real clinical environment. This research contributes to a more complete cardiovascular examination without significant additional discomfort for the patient or prolongation of the test protocol.
为了提高心血管风险人群的早期诊断,我们正在开发一种定制设备,基于无创获取压力(动脉血压计)和血流(多普勒超声技术)波形,允许对心脏功能和动脉循环特性进行充分的血液动力学分析。在一个实验环境中,15名健康志愿者在一辆定制的仰卧自行车上接受了检查。能够在整个自行车测试过程中记录可用数据,并自动分析衍生的血流动力学参数,如顺应性,外周阻力等,我们也将该设置应用于真实的临床环境。这项研究有助于更完整的心血管检查,而不会给患者带来明显的额外不适或延长测试方案。
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引用次数: 4
Feasibility of atrial activation time imaging 心房激活时间成像的可行性
Pub Date : 2002-09-22 DOI: 10.1109/CIC.2002.1166844
F. Hanser, B. Tilg, R. Modre, G. Fischer, B. Messnarz, F. Hintringer, F. Roithinger
The feasibility of atrial activation time imaging is investigated based on data sets of four patients who underwent an electrophysiologic study. Several pacing protocols with pacing sites at the right atrial appendage, coronary sinus, and high right atrium were part of the study and were employed to reconstruct the associated atrial activation time patterns. The localization error was estimated to be between 8 and 14 mm.
心房激活时间成像的可行性进行了调查,基于数据集的四个病人谁接受了电生理研究。在右心房附件、冠状动脉窦和右心房高位起搏的几种起搏方案是研究的一部分,并用于重建相关的心房激活时间模式。定位误差估计在8 ~ 14 mm之间。
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引用次数: 2
Need of causal analysis for assessing phase relationships in closed loop interacting cardiovascular variability series 需要因果分析来评估闭环相互作用心血管变异性系列的相位关系
Pub Date : 2002-09-22 DOI: 10.1109/CIC.2002.1166707
G. Nollo, L. Widesott, L. Faes, A. Porta, R. Antolini
The phase spectra obtained by the classical closed loop autoregressive model (2AR) and by an open loop autoregressive model (ARXAR) were compared to shed light on the need of introducing causality in the assessment of the delay between RR and arterial pressure oscillations. The reliability of the two approaches was tested in simulation and real data setting. In simulation, the coupling strength of a bivariate closed loop process was adjusted to obtain a range of working conditions from open to closed loop. In open loop condition, 2AR and ARXAR phases were comparable and in agreement with the imposed delay. In closed loop condition, ARXAR model returned the imposed delays, while 2AR showed an intermediate value of delay. Real data were chosen to represent comparable physiological condition. The use of cross spectrum for calculating the delay from arterial pressure to RR oscillations seems adequate only in particular condition of open-loop relationship as it happens during head up tilt in young healthy subjects.
通过比较经典闭环自回归模型(2AR)和开环自回归模型(ARXAR)获得的相位谱,揭示了在评估RR和动脉压振荡之间的延迟时引入因果关系的必要性。在仿真和实际数据设置中验证了两种方法的可靠性。在仿真中,对二元闭环过程的耦合强度进行调整,得到从开环到闭环的一系列工况。在开环条件下,2AR和ARXAR相位具有可比性,并且与所施加的延迟一致。在闭环条件下,ARXAR模型返回强加的延迟,而2AR模型显示延迟的中间值。选择真实数据来代表可比的生理状况。使用交叉谱来计算动脉压到RR振荡的延迟似乎只适用于开环关系的特定条件,因为它发生在年轻健康受试者的头部向上倾斜期间。
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引用次数: 0
Wavelets extrema representation for QRS-T cancellation and P wave detection 小波极值表示用于QRS-T对消和P波检测
Pub Date : 2002-09-22 DOI: 10.1109/CIC.2002.1166701
L. Senhadji, Feng Wang, Alfredo I. Hernández, Guy Carrault
P wave detection requires a robust QRS-T cancellation method. Interesting algorithms have been proposed for beat-to-beat QRS-T cancellation. Previous studies have shown that adaptive methods lead to good cancellation of the QRS-T interval which generally guarantees the performance of P wave detection. However, adaptive methods suffer from the nonstationary behavior of ECG signals and particularly beat-to-beat morphology changes of the QRS. We present a new approach for two ECG channel QRS-T cancellation based on the dyadic wavelet transform. The method is insensitive to QRS morphology changes and performs well in the presence of ectopic beats, transient artifacts, baseline drifts and isolated P waves. Our approach allows the P wave to be enhanced better than methods recently proposed.
P波检测需要一种鲁棒的QRS-T对消方法。有趣的算法已经提出了拍对拍QRS-T抵消。已有研究表明,自适应方法可以很好地抵消QRS-T区间,一般可以保证P波检测的性能。然而,自适应方法受到心电信号的非平稳行为,特别是QRS的搏动形态学变化的影响。提出了一种基于二进小波变换的双心电通道QRS-T对消方法。该方法对QRS形态学变化不敏感,在异位拍、瞬态伪影、基线漂移和孤立P波存在时表现良好。我们的方法可以比最近提出的方法更好地增强P波。
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引用次数: 25
Improved discrimination of VT from SVT in dual-chamber ICDs by combined analysis of dual-chamber intervals and ventricular electrogram morphology 联合分析双室间期和心室电图形态,提高双室icd VT与SVT的鉴别
Pub Date : 2002-09-22 DOI: 10.1109/CIC.2002.1166721
M.L. Brown, J. Christensen, J. Gillberg
The PR Logic dual-chamber defection algorithm discriminates VT/VF from SVT using hierarchical rules based on the pattern and timing of AA, VV, AV, and VA intervals. It cannot always discriminate rapidly-conducted atrial fibrillation(AF) from double tachycardia. Coexisting AF and VT/VF, or SVT with 1:1 antegrade conduction from VT with 1:1 retrograde conduction. This study evaluated a new tachyarrhythmia detection algorithm that supplements analysis of dual-chamber intervals with analysis of ventricular electrogram morphology based on the Wavelet Dynamic Discrimination Algorithm. Combined analysis of dual-chamber intervals and ventricular electrogram morphology reduced inappropriate detection of SVTs by 79% compared to dual chamber intervals alone without compromising sensitivity for detection of VT/VF.
PR Logic双腔检测算法利用基于AA、VV、AV和VA间隔的模式和时间的分层规则来区分VT/VF和SVT。它不能总是区分快速传导的心房颤动(AF)和双速心动过速。房颤和VT/VF共存,或SVT由VT与1:1逆行传导成1:1顺行传导。本研究提出了一种新的基于小波动态判别算法的快速心律失常检测算法,该算法在分析双室间期的同时分析心室电图形态。与单独双室间隔相比,联合分析双室间隔和心室电图形态学减少了79%的svt不适当检测,而不影响检测VT/VF的敏感性。
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引用次数: 2
Analysis of non-invasively recorded His-Purkinje signals from patients with myotonic muscular dystrophy 肌强直性肌营养不良患者无创记录的His-Purkinje信号分析
Pub Date : 2002-09-22 DOI: 10.1109/CIC.2002.1166766
H. Park, W. Groh, W. Combs, E. Berbari
This study presents several new approaches to analyze the non-invasively recorded His-Purkinje system (HPS) signals from patients with myotonic muscular dystrophy. A high resolution electrocardiogram based on signal averaging to improve the signal-to-noise ratio(SNR) is a well established means to record HPS potentials. These new approaches used methods to temporally and spectrally separate the HPS potentials from the P wave potentials. These included both physiologically based and signal processing based schemes. Separating or shifting the P wave from the HPS potentials using heart rate dependent averaging and the addition of several highpass filtering methods proved somewhat, but not totally successful. In the group of patients with sequential recordings over a period of two years the progression of their muscular dystrophy may also be seen in the heart as well. This may then produce noticeable progressive trends or changes in their HPS waveforms over time. The most noticeable changes found in this study were temporal changes and morphological changes of the HPS activity of these patients over time.
本研究提出了几种新的方法来分析肌强直性肌营养不良患者的无创记录his -浦肯野系统(HPS)信号。基于信号平均的高分辨率心电图,提高了信噪比(SNR),是记录HPS电位的一种行之有效的方法。这些新方法利用时间和频谱方法将HPS电位与P波电位分离开来。这些包括基于生理学和基于信号处理的方案。利用心率相关的平均和几种高通滤波方法将P波从HPS电位中分离或移位,在一定程度上证明了这一点,但并不完全成功。在两年内连续记录的患者组中,他们的肌肉萎缩症的进展也可以在心脏中看到。随着时间的推移,这可能会产生明显的渐进式趋势或HPS波形的变化。本研究中最显著的变化是这些患者的HPS活性随时间的变化和形态学变化。
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引用次数: 0
Decision fusion of micro-variability and signal averaged ECG parameters from the QRS complex with RBF networks 基于RBF网络的微变异性与信号平均心电参数的决策融合
Pub Date : 2002-09-22 DOI: 10.1109/CIC.2002.1166767
H. Kestler, A. Muller, V. Hombach, J. Wohrle, O. Grebe, G. Palm, M. Moher, F. Schwenker
Two types of measurements are usually performed from high resolution ECG recordings: (a) static parameters derived from the signal-averaged QRS complex and (b) variant markers derived from beat-to-beat recordings. It is known that an increased QRS micro-variability and ventricular late potentials are associated with an increased risk for malignant arrhythmias. However, the diagnostic power of the singular parameters is limited In this study we investigated the diagnostic ability of a decision fusion of both variant and static high-resolution ECG parameters with radial-basis-function (RBF) networks. Continuous and signal-averaged ECGs were recorded from 51 healthy volunteers without any structural heart disease and no cardiac risk factors and from 44 patients with coronary heart disease and ventricular arrhythmias. Beat-to-beat micro-variability measurement of the QRS complex and the ST-T segment was based on 250 consecutive sinus beats per individual. Signal-averaged ECGs were analyzed with the Simson method (QRSD, RMS, LAS). Two RBF networks were trained One on the three signal averaged parameters and one with the 141D variability vector The two soft decisions from each RBF network were then combined by average fusion and maximum detection into a final crisp decision which resulted in an unusually high discriminative accuracy.
通常从高分辨率ECG记录中进行两种类型的测量:(a)从信号平均QRS复合物中获得的静态参数和(b)从心跳记录中获得的可变标记。众所周知,增加的QRS微变异性和心室晚期电位与恶性心律失常的风险增加有关。然而,单一参数的诊断能力是有限的。在本研究中,我们研究了基于径向基函数(RBF)网络的可变和静态高分辨率ECG参数决策融合的诊断能力。记录了51名没有任何结构性心脏病和心脏危险因素的健康志愿者和44名冠心病和室性心律失常患者的连续和信号平均心电图。QRS复合体和ST-T段的搏动微变异性测量是基于每个人连续250次窦性搏动。采用Simson方法(QRSD, RMS, LAS)分析信号平均心电图。两个RBF网络分别在三个信号平均参数和141D变异向量上进行训练,然后通过平均融合和最大检测将每个RBF网络的两个软决策组合成最终的清晰决策,从而获得异常高的判别精度。
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引用次数: 1
A real time QRS complex classification method using Mahalanobis distance 基于马氏距离的QRS实时复杂分类方法
Pub Date : 2002-09-22 DOI: 10.1109/CIC.2002.1166742
J. Moraes, M.O. Seixas, F.N. Vilani, E.V. Costa
An unsupervised method to recognize and classify QRS complexes was developed in order to create an automatic cardiac beat classifier in real time. After exhaustive analysis, four features extracted from the QRS complex in the time domain were selected as the ones presenting the best results: width, total sum of the areas under the positive and negative curves, total sum of the absolute values of sample variations and total amplitude. Preliminary studies indicated these features follow a normal distribution, allowing the use of the Mahalanobis distance as their classification criterion. After an initial learning period, the algorithm extracts the four features from every new QRS complex and calculates the Mahalanobis distance between its feature set and the centroids of all existing classes to determine the class in which the new QRS belongs to. If a predefined distance is surpassed, a new class is created Using 44 records from the MIT-BIH we have obtained 90,74% of sensitivity, 96,55% of positive predictivity and 0.242% of false positives.
为了建立实时自动心跳分类器,提出了一种无监督的QRS复合体识别和分类方法。经过详尽的分析,从QRS复合体提取的时域特征中,选择宽度、正负曲线下面积之和、样本变化绝对值之和和总幅值四个特征作为效果最好的特征。初步研究表明,这些特征遵循正态分布,允许使用马氏距离作为它们的分类标准。经过一段初始学习期后,算法从每个新的QRS复合体中提取出四个特征,并计算其特征集与所有现有类的质心之间的马氏距离,从而确定新的QRS属于哪个类。如果超过预定义的距离,则创建一个新的类。使用来自MIT-BIH的44条记录,我们获得了9074%的灵敏度,96,55%的阳性预测和0.242%的假阳性。
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引用次数: 63
Low-voltage defibrillation in bidomain virtual ventricular tissue: effect of the bath 低压除颤在双域虚拟心室组织中的作用
Pub Date : 2002-09-22 DOI: 10.1109/CIC.2002.1166756
O. Aslanidi, O. Mornev, A. Holden
Mechanisms for termination of re-entry and defibrillation still remain a challenge. Using the Luo-Rudy family of virtual ventricular tissues we simulate termination of re-entrant spiral waves with a periodic low-voltage shock studying a new mechanism for defibrillation. Essential for the simulations is extension of the bidomain tissue representation in order to account for the existence of an external bath ("tridomain"), where the shock is applied The bidomain model with the bath reproduces periodic patterns of depolarization in the virtual tissue - standing waves, previously observed in experiments. In contrast to the classical exponential decay of voltage near the electrodes, standing waves entrain the whole tissue, thus canceling the spiral waves. The mechanism of this far-field effect is based on redistribution of the externally applied current by the conductive bath.
再入和除颤的终止机制仍然是一个挑战。利用虚拟心室组织的Luo-Rudy家族,我们模拟了周期性低压冲击下再入螺旋波的终止,研究了除颤的新机制。模拟的关键是扩展比多域组织表示,以解释外部浴槽(“三角域”)的存在,在那里施加冲击。带有浴槽的比多域模型再现了以前在实验中观察到的虚拟组织驻波中的周期性去极化模式。与经典的电极附近电压指数衰减相反,驻波在整个组织中传播,从而抵消了螺旋波。这种远场效应的机理是基于导电槽对外部施加电流的重新分配。
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引用次数: 3
期刊
Computers in cardiology
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