{"title":"Nebulized Tranexamic Acid in Low- to Medium-abundance Hemoptysis: A Retrospective Study of Current Practices","authors":"Virgile Caban , Julie Tronchetti , Jean-Baptiste Lovato , Stéphanie Martinez , Hervé Dutau , Philippe Astoul","doi":"10.1016/j.arbres.2025.06.014","DOIUrl":"10.1016/j.arbres.2025.06.014","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 12","pages":"Pages 791-793"},"PeriodicalIF":9.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144641627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01DOI: 10.1016/j.arbres.2025.09.017
Win Pa Pa Thu , Ting Huey Hu , Lia D’Ambrosio , Rosella Centis , Catherine W.M. Ong , Giovanni Battista Migliori
Post-Tuberculosis Lung Disease (PTLD), a persistent sequelae of Tuberculosis (TB) in which TB survivors continue to experience respiratory symptoms and diminished lung function after microbiological cure, poses a significant and growing public health challenge. Its prevalence varies widely due to differences in treatment adequacy, comorbidities, and environmental exposures and afflicts particularly high TB-burden countries. Recent advances in fundamental science, clinical investigations and exploratory trials have expanded our understanding of PTLD pathogenesis and progression. Yet, critical questions remain unanswered: Which patients are most at risk? How can we intervene early to prevent or mitigate disability? And how should healthcare systems adapt to monitor, manage, and support the growing population of TB survivors?
This review aims to inform ongoing efforts in clinical care, research, and policy. We summarize recent evidence on PTLD—specifically disease mechanisms, clinical manifestations, diagnostic approaches, risk factors, and treatment strategies. It also highlights key knowledge gaps and implementation challenges and proposes research priorities to steer future inquiry and practice. Greater research investment and stronger global collaboration are needed to mitigate the long-term burden of PTLD and improve outcomes for TB survivors.
{"title":"Charting the Course in Post-Tuberculosis Lung Disease: From Inflammation to Intervention","authors":"Win Pa Pa Thu , Ting Huey Hu , Lia D’Ambrosio , Rosella Centis , Catherine W.M. Ong , Giovanni Battista Migliori","doi":"10.1016/j.arbres.2025.09.017","DOIUrl":"10.1016/j.arbres.2025.09.017","url":null,"abstract":"<div><div>Post-Tuberculosis Lung Disease (PTLD), a persistent sequelae of Tuberculosis (TB) in which TB survivors continue to experience respiratory symptoms and diminished lung function after microbiological cure, poses a significant and growing public health challenge. Its prevalence varies widely due to differences in treatment adequacy, comorbidities, and environmental exposures and afflicts particularly high TB-burden countries. Recent advances in fundamental science, clinical investigations and exploratory trials have expanded our understanding of PTLD pathogenesis and progression. Yet, critical questions remain unanswered: Which patients are most at risk? How can we intervene early to prevent or mitigate disability? And how should healthcare systems adapt to monitor, manage, and support the growing population of TB survivors?</div><div>This review aims to inform ongoing efforts in clinical care, research, and policy. We summarize recent evidence on PTLD—specifically disease mechanisms, clinical manifestations, diagnostic approaches, risk factors, and treatment strategies. It also highlights key knowledge gaps and implementation challenges and proposes research priorities to steer future inquiry and practice. Greater research investment and stronger global collaboration are needed to mitigate the long-term burden of PTLD and improve outcomes for TB survivors.</div></div>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 12","pages":"Pages 757-765"},"PeriodicalIF":9.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145426605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-27DOI: 10.1016/j.arbres.2025.11.008
Marina Acebo Castro, Juan Diego Álvarez Mavárez
{"title":"Pneumoconiosis Associated With Occupational Exposure to Calcium Stearate: First Case With Mineralogical Confirmation.","authors":"Marina Acebo Castro, Juan Diego Álvarez Mavárez","doi":"10.1016/j.arbres.2025.11.008","DOIUrl":"https://doi.org/10.1016/j.arbres.2025.11.008","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2025-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145803190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-27DOI: 10.1016/j.arbres.2025.11.009
Claudia Mañana Valdés, Marina Acebo Castro, Marta María García Clemente
{"title":"Massive Pleural Effusion Due to Mycobacterium xenopi in an Immunocompetent Patient: A Case Report.","authors":"Claudia Mañana Valdés, Marina Acebo Castro, Marta María García Clemente","doi":"10.1016/j.arbres.2025.11.009","DOIUrl":"https://doi.org/10.1016/j.arbres.2025.11.009","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2025-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145740530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-20DOI: 10.1016/j.arbres.2025.11.007
Gerald S Zavorsky
{"title":"Challenges of DLNO 40 Years After its Invention.","authors":"Gerald S Zavorsky","doi":"10.1016/j.arbres.2025.11.007","DOIUrl":"https://doi.org/10.1016/j.arbres.2025.11.007","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145666816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-20DOI: 10.1016/j.arbres.2025.11.006
Alyson W Wong, Christopher J Ryerson
{"title":"Defining Progressive Pulmonary Fibrosis: Implications for Clinical Trials, Guidelines, and Patient Care.","authors":"Alyson W Wong, Christopher J Ryerson","doi":"10.1016/j.arbres.2025.11.006","DOIUrl":"https://doi.org/10.1016/j.arbres.2025.11.006","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145660098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-20DOI: 10.1016/j.arbres.2025.11.005
Jacopo Cefalo, Francesco Varone, Fabrizio Luppi, Paolo Cameli, Stefania Cerri, Mariangela Valentina Puci, Alessia Martini, Giovanni Franco, Umberto Zanini, Tommaso Pianigiani, Athina Patsoura, Luca Richeldi, Elena Bargagli, Giovanni Sotgiu, Michele Mondoni
{"title":"Impact of Dosing on Functional and Clinical Outcomes of Patients With Progressive Pulmonary Fibrosis Treated With Nintedanib: Data From a Real-World, Multicentric, Italian Study.","authors":"Jacopo Cefalo, Francesco Varone, Fabrizio Luppi, Paolo Cameli, Stefania Cerri, Mariangela Valentina Puci, Alessia Martini, Giovanni Franco, Umberto Zanini, Tommaso Pianigiani, Athina Patsoura, Luca Richeldi, Elena Bargagli, Giovanni Sotgiu, Michele Mondoni","doi":"10.1016/j.arbres.2025.11.005","DOIUrl":"https://doi.org/10.1016/j.arbres.2025.11.005","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145666843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-14DOI: 10.1016/j.arbres.2025.11.002
Winnifer Briceño, Juan Manuel Velasco, Ana Castillo, Ignacio Jara, Laura Lago, Edwin Yong, Gema Díaz, Gregory Piazza, Behnood Bikdeli, David Jiménez
Background: In patients with acute symptomatic pulmonary embolism (PE), embolic burden has an uncertain prognostic significance.
Methods: We performed a meta-analysis of studies including patients with PE to assess the prevalence and prognostic relevance of central PE (i.e., saddle or main pulmonary emboli) for short-term death and other adverse outcome events. A random-effects model was used to pool study results, and I2 testing was used to test for heterogeneity.
Results: Data from 28 studies (205,877 patients) were included in the analysis. Of the 26 studies with 205,410 participants that enrolled consecutive patients with PE, 7748 (3.8%) had central PE. Though there was no statistically significant difference between central and noncentral PE for odds of short-term all-cause mortality (odds ratio [OR] 1.19; 95% confidence interval [CI], 0.91-1.55), central PE had a significant association with short-term PE-related deterioration or death (OR, 2.47; 95% CI, 1.44-4.25). Results from 9 studies with 4325 PE patients that had available data showed that central PE had a significant association with the odds of short-term PE-related mortality (OR, 1.77; 95% CI, 1.22-2.55). Results were consistent for prospective (OR, 1.67; 95% CI, 1.21-2.32), and studies that only enrolled stable patients (OR, 1.42; 95% CI, 1.06-1.92).
Conclusions: Central PE was an uncommon finding in unselected patients diagnosed with PE. While central thrombus did not have an association with increased risk of all-cause mortality, it was significantly associated with an increased risk of PE-related deterioration and death short after diagnosis.
{"title":"Prevalence and Prognostic Relevance of Central Pulmonary Embolism: Systematic Review and Meta-Analysis.","authors":"Winnifer Briceño, Juan Manuel Velasco, Ana Castillo, Ignacio Jara, Laura Lago, Edwin Yong, Gema Díaz, Gregory Piazza, Behnood Bikdeli, David Jiménez","doi":"10.1016/j.arbres.2025.11.002","DOIUrl":"https://doi.org/10.1016/j.arbres.2025.11.002","url":null,"abstract":"<p><strong>Background: </strong>In patients with acute symptomatic pulmonary embolism (PE), embolic burden has an uncertain prognostic significance.</p><p><strong>Methods: </strong>We performed a meta-analysis of studies including patients with PE to assess the prevalence and prognostic relevance of central PE (i.e., saddle or main pulmonary emboli) for short-term death and other adverse outcome events. A random-effects model was used to pool study results, and I<sup>2</sup> testing was used to test for heterogeneity.</p><p><strong>Results: </strong>Data from 28 studies (205,877 patients) were included in the analysis. Of the 26 studies with 205,410 participants that enrolled consecutive patients with PE, 7748 (3.8%) had central PE. Though there was no statistically significant difference between central and noncentral PE for odds of short-term all-cause mortality (odds ratio [OR] 1.19; 95% confidence interval [CI], 0.91-1.55), central PE had a significant association with short-term PE-related deterioration or death (OR, 2.47; 95% CI, 1.44-4.25). Results from 9 studies with 4325 PE patients that had available data showed that central PE had a significant association with the odds of short-term PE-related mortality (OR, 1.77; 95% CI, 1.22-2.55). Results were consistent for prospective (OR, 1.67; 95% CI, 1.21-2.32), and studies that only enrolled stable patients (OR, 1.42; 95% CI, 1.06-1.92).</p><p><strong>Conclusions: </strong>Central PE was an uncommon finding in unselected patients diagnosed with PE. While central thrombus did not have an association with increased risk of all-cause mortality, it was significantly associated with an increased risk of PE-related deterioration and death short after diagnosis.</p>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2025-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145660050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-14DOI: 10.1016/j.arbres.2025.11.004
Javier Sayas Catalán, Maxime Patout
{"title":"Breathing on the Bench: Are We Over-simulating or Underestimating NIV Realities? A PRO/CON Debate.","authors":"Javier Sayas Catalán, Maxime Patout","doi":"10.1016/j.arbres.2025.11.004","DOIUrl":"https://doi.org/10.1016/j.arbres.2025.11.004","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2025-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145628234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-14DOI: 10.1016/j.arbres.2025.11.003
Francisco Javier Álvarez-Gutiérrez, Francisco Casas-Maldonado, José Valverde-Molina
{"title":"News From the Severe Asthma Consensus 2025 Review.","authors":"Francisco Javier Álvarez-Gutiérrez, Francisco Casas-Maldonado, José Valverde-Molina","doi":"10.1016/j.arbres.2025.11.003","DOIUrl":"https://doi.org/10.1016/j.arbres.2025.11.003","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2025-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145628276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号