Pub Date : 2024-09-24DOI: 10.1016/j.arbres.2024.09.002
Emilio Burgui Gualda, Ignacio Sáez de la Fuente, José Ángel Sánchez Izquierdo Riera
{"title":"Venovenous ECMO Weaning Failure. Utilization of Extracorporeal CO<sub>2</sub> Removal (ECCO<sub>2</sub>R) as a Bridge Therapy in ECMO Weaning: A Case Report.","authors":"Emilio Burgui Gualda, Ignacio Sáez de la Fuente, José Ángel Sánchez Izquierdo Riera","doi":"10.1016/j.arbres.2024.09.002","DOIUrl":"https://doi.org/10.1016/j.arbres.2024.09.002","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":null,"pages":null},"PeriodicalIF":8.7,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142387479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-24DOI: 10.1016/j.arbres.2024.09.005
Donal O'Malley, Adam J Byrne, Michael P Keane, Cormac McCarthy
{"title":"Lymphangioleiomyomatosis and its Treatment: When to Start?","authors":"Donal O'Malley, Adam J Byrne, Michael P Keane, Cormac McCarthy","doi":"10.1016/j.arbres.2024.09.005","DOIUrl":"10.1016/j.arbres.2024.09.005","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":null,"pages":null},"PeriodicalIF":8.7,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142374994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-24DOI: 10.1016/j.arbres.2024.09.006
José Luis Lopez-Campos, Federico Manresa Presas, Juan Ruiz Manzano, Miguel Perpiñá Tordera, Pere Casan Clara, Francisco García-Río, Esther Barreiro, Miguel Angel Martinez García
{"title":"Archivos de Bronconeumología: 60 Years and Going on.","authors":"José Luis Lopez-Campos, Federico Manresa Presas, Juan Ruiz Manzano, Miguel Perpiñá Tordera, Pere Casan Clara, Francisco García-Río, Esther Barreiro, Miguel Angel Martinez García","doi":"10.1016/j.arbres.2024.09.006","DOIUrl":"https://doi.org/10.1016/j.arbres.2024.09.006","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":null,"pages":null},"PeriodicalIF":8.7,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142456840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-03DOI: 10.1016/j.arbres.2024.07.018
Mireia Dalmases, Manuel Sánchez-de-la-Torre, Dolores Martinez, Olga Minguez, Rafaela Vaca, Lydia Pascual, Maria Aguilá, Esther Gracia-Lavedan, Ivan D Benitez, Lucía Pinilla, Anunciación Cortijo, Clara Gort-Paniello, Ramon Bascompte Claret, Miguel Ángel Martinez-Garcia, Olga Mediano, Sofía Romero Peralta, Ana Maria Fortuna-Gutierrez, Paola Ponte Marquez, Luciano F Drager, Mayara Cabrini, Juan Fernando Masa, Jaime Corral Peñafiel, Susana Vázquez, Jorge Abad, Francisco García-Rio, Raquel Casitas, Chi-Hang Lee, Ferran Barbé, Gerard Torres
Introduction: Among all patients with hypertension, those with resistant hypertension (RH) have the highest rates of subclinical organ damage (SOD). The prevalence of obstructive sleep apnea (OSA) is high in RH patients, and it could contribute to SOD. We aimed to investigate how OSA and its treatment are related to SOD in a large cohort of RH patients.
Methods: This is an ancillary analysis to the SARAH study, a multicentre observational cohort aiming to evaluate the impact of OSA on RH. Individuals with RH who were undergoing a sleep study and have information on at least one of the SOD variables (vascular, cardiac or renal damage) were selected. Patients were followed-up for three years.
Results: In total, 503 subjects were included. The participants were predominantly male, obese, and the median (IQR) apnea-hypopnea index (AHI) was 15.5 (7.90-31.5)events/h. No differences in the presence of vascular or cardiac damage were observed between OSA and non-OSA patients. A lower estimated glomerular filtration rate (eGFR) was observed in participants with OSA than in those without OSA, with an adjusted effect of -8.69mL/min/1.73m2 (-13.59, -3.79; p value<0.001). Kidney damage was also greater in subjects with OSA, with an adjusted OR (95% CI) of 1.77 (1.09, 2.87; p value=0.02). The eGFR showed a linear dose-response relationship with OSA severity. Among patients treated with CPAP, lower eGFR values were observed in noncompliant subjects.
Conclusions: OSA could contribute to worsening renal function in patients with RH. No compliance with CPAP was associated with lower values of eGFR.
简介在所有高血压患者中，抵抗性高血压（RH）患者的亚临床器官损伤（SOD）发生率最高。阻塞性睡眠呼吸暂停（OSA）在抵抗性高血压患者中的发病率很高，这可能是导致 SOD 的原因之一。我们的目的是在一大批 RH 患者中调查 OSA 及其治疗与 SOD 的关系：这是 SARAH 研究的一项辅助分析，该研究是一项多中心观察性队列研究，旨在评估 OSA 对 RH 的影响。研究选取了正在接受睡眠研究且至少有一项SOD变量（血管、心脏或肾脏损伤）信息的RH患者。对患者进行了为期三年的随访：结果：共纳入 503 名受试者。参与者主要为男性、肥胖者，呼吸暂停-低通气指数（AHI）的中位数（IQR）为 15.5（7.90-31.5）次/小时。OSA患者与非OSA患者在血管或心脏损伤方面没有差异。与非 OSA 患者相比，OSA 患者的估计肾小球滤过率（eGFR）更低，调整后的影响值为-8.69mL/min/1.73m2（-13.59，-3.79；P 值）：OSA可能导致RH患者肾功能恶化。不使用 CPAP 与 eGFR 值降低有关。
{"title":"The Effect of Obstructive Sleep Apnea on Subclinical Target Organ Damage in Patients With Resistant Hypertension.","authors":"Mireia Dalmases, Manuel Sánchez-de-la-Torre, Dolores Martinez, Olga Minguez, Rafaela Vaca, Lydia Pascual, Maria Aguilá, Esther Gracia-Lavedan, Ivan D Benitez, Lucía Pinilla, Anunciación Cortijo, Clara Gort-Paniello, Ramon Bascompte Claret, Miguel Ángel Martinez-Garcia, Olga Mediano, Sofía Romero Peralta, Ana Maria Fortuna-Gutierrez, Paola Ponte Marquez, Luciano F Drager, Mayara Cabrini, Juan Fernando Masa, Jaime Corral Peñafiel, Susana Vázquez, Jorge Abad, Francisco García-Rio, Raquel Casitas, Chi-Hang Lee, Ferran Barbé, Gerard Torres","doi":"10.1016/j.arbres.2024.07.018","DOIUrl":"https://doi.org/10.1016/j.arbres.2024.07.018","url":null,"abstract":"<p><strong>Introduction: </strong>Among all patients with hypertension, those with resistant hypertension (RH) have the highest rates of subclinical organ damage (SOD). The prevalence of obstructive sleep apnea (OSA) is high in RH patients, and it could contribute to SOD. We aimed to investigate how OSA and its treatment are related to SOD in a large cohort of RH patients.</p><p><strong>Methods: </strong>This is an ancillary analysis to the SARAH study, a multicentre observational cohort aiming to evaluate the impact of OSA on RH. Individuals with RH who were undergoing a sleep study and have information on at least one of the SOD variables (vascular, cardiac or renal damage) were selected. Patients were followed-up for three years.</p><p><strong>Results: </strong>In total, 503 subjects were included. The participants were predominantly male, obese, and the median (IQR) apnea-hypopnea index (AHI) was 15.5 (7.90-31.5)events/h. No differences in the presence of vascular or cardiac damage were observed between OSA and non-OSA patients. A lower estimated glomerular filtration rate (eGFR) was observed in participants with OSA than in those without OSA, with an adjusted effect of -8.69mL/min/1.73m<sup>2</sup> (-13.59, -3.79; p value<0.001). Kidney damage was also greater in subjects with OSA, with an adjusted OR (95% CI) of 1.77 (1.09, 2.87; p value=0.02). The eGFR showed a linear dose-response relationship with OSA severity. Among patients treated with CPAP, lower eGFR values were observed in noncompliant subjects.</p><p><strong>Conclusions: </strong>OSA could contribute to worsening renal function in patients with RH. No compliance with CPAP was associated with lower values of eGFR.</p>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":null,"pages":null},"PeriodicalIF":8.7,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-01DOI: 10.1016/j.arbres.2024.05.009
Introduction
The impact of obstructive lung disease (OLD) and emphysema on lung cancer (LC) mortality in patients undergoing LC screening is controversial.
Methods
Patients with spirometry and LC diagnosed within the first three rounds of screening were selected from the National Lung Screening Trial (NLST) and from the Pamplona International Early Lung Cancer Detection Program (P-IELCAP). Medical and demographic data, tumor characteristics, comorbidities and presence of emphysema were collected. The effect of OLD and emphysema on the risk of overall survival was assessed using unadjusted and adjusted Cox models, competing risk regression analysis, and propensity score matching.
Results
Data from 353 patients with LC, including 291 with OLD and/or emphysema and 62 with neither, were analyzed. The median age was 67.3 years-old and 56.1% met OLD criteria, predominantly mild (1: 28.3%, 2: 65.2%). Emphysema was present in 69.4% of the patients. Patients with OLD and/or emphysema had worse survival on univariate analysis (HR: 1.40; 95% CI: 0.86–2.31; p = 0.179). However, after adjusting for LC stage, age, and sex, the HR was 1.02 (95% CI: 0.61–1.70; p = 0.952). Specific LC survival between both groups showed an adjusted HR of 0.90 (95% CI: 0.47–1.72; p = 0.76). Propensity score matching found no statistically significant difference in overall survival (HR: 1.03; 95% CI: 0.59–1.9; p = 0.929).
Conclusion
The survival of LC patients diagnosed in the context of screening is not negatively impacted by the coexistence of mild OLD and/or emphysema.
{"title":"Impact of OLD/Emphysema in LC Mortality Risk in Screening Programs: An Analysis of NLST and P-IELCAP","authors":"","doi":"10.1016/j.arbres.2024.05.009","DOIUrl":"10.1016/j.arbres.2024.05.009","url":null,"abstract":"<div><h3>Introduction</h3><p>The impact of obstructive lung disease<span> (OLD) and emphysema on lung cancer (LC) mortality in patients undergoing LC screening is controversial.</span></p></div><div><h3>Methods</h3><p><span><span><span><span>Patients with spirometry and LC diagnosed within the first three rounds of screening were selected from the </span>National Lung Screening Trial<span> (NLST) and from the Pamplona International Early Lung Cancer Detection Program (P-IELCAP). Medical and demographic data, tumor characteristics, comorbidities and presence of emphysema were collected. The effect of </span></span>OLD and emphysema on the risk of </span>overall survival<span> was assessed using unadjusted and adjusted Cox models, competing risk regression analysis, and </span></span>propensity score matching.</p></div><div><h3>Results</h3><p><span>Data from 353 patients with LC, including 291 with OLD and/or emphysema and 62 with neither, were analyzed. The median age was 67.3 years-old and 56.1% met OLD criteria, predominantly mild (1: 28.3%, 2: 65.2%). Emphysema was present in 69.4% of the patients. Patients with OLD and/or emphysema had worse survival on univariate analysis (HR: 1.40; 95% CI: 0.86–2.31; </span><em>p</em> <!-->=<!--> <!-->0.179). However, after adjusting for LC stage, age, and sex, the HR was 1.02 (95% CI: 0.61–1.70; <em>p</em> <!-->=<!--> <span>0.952). Specific LC survival between both groups showed an adjusted HR of 0.90 (95% CI: 0.47–1.72; </span><em>p</em> <!-->=<!--> <!-->0.76). Propensity score matching found no statistically significant difference in overall survival (HR: 1.03; 95% CI: 0.59–1.9; <em>p</em> <!-->=<!--> <!-->0.929).</p></div><div><h3>Conclusion</h3><p>The survival of LC patients diagnosed in the context of screening is not negatively impacted by the coexistence of mild OLD and/or emphysema.</p></div>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":null,"pages":null},"PeriodicalIF":8.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141040511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-01DOI: 10.1016/j.arbres.2024.06.004
{"title":"Bronchoscopy in Severe Asthmatics: Is it a Safe Procedure?","authors":"","doi":"10.1016/j.arbres.2024.06.004","DOIUrl":"10.1016/j.arbres.2024.06.004","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":null,"pages":null},"PeriodicalIF":8.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141490695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-01DOI: 10.1016/j.arbres.2024.05.026
Chronic respiratory diseases (CRD) are responsible for more than four million deaths worldwide and have become especially prevalent in developed countries. Although the current therapies help manage daily symptoms and improve patients’ quality of life, there is a major need to prevent exacerbations triggered mainly by respiratory infections. Therefore, CRD patients are a prime target for vaccination against infectious agents. In the present manuscript we review the state of the art of available vaccines specifically indicated in patients with CRDs. In addition to pneumococcus, influenza, pertussis, and SARS-CoV-2 vaccines, recently added immunization options like vaccines and monoclonal antibodies against respiratory syncytial virus, are particularly interesting in CRD patients. As new products reach the market, health authorities must be agile in updating immunization recommendations and in the programming of the vaccination of vulnerable populations such as patients with CRDs. Organizational and educational strategies might prove useful to increase vaccine uptake by CRD patients.
{"title":"New Vaccines for Chronic Respiratory Patients","authors":"","doi":"10.1016/j.arbres.2024.05.026","DOIUrl":"10.1016/j.arbres.2024.05.026","url":null,"abstract":"<div><p>Chronic respiratory diseases (CRD) are responsible for more than four million deaths worldwide and have become especially prevalent in developed countries. Although the current therapies help manage daily symptoms and improve patients’ quality of life, there is a major need to prevent exacerbations triggered mainly by respiratory infections. Therefore, CRD patients are a prime target for vaccination against infectious agents. In the present manuscript we review the state of the art of available vaccines specifically indicated in patients with CRDs. In addition to pneumococcus, influenza, pertussis, and SARS-CoV-2 vaccines, recently added immunization options like vaccines and monoclonal antibodies against respiratory syncytial virus, are particularly interesting in CRD patients. As new products reach the market, health authorities must be agile in updating immunization recommendations and in the programming of the vaccination of vulnerable populations such as patients with CRDs. Organizational and educational strategies might prove useful to increase vaccine uptake by CRD patients.</p></div>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":null,"pages":null},"PeriodicalIF":8.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S030028962400190X/pdfft?md5=56aec3812ee5aba9384ca3d7da3dfda5&pid=1-s2.0-S030028962400190X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141320390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-01DOI: 10.1016/j.arbres.2024.05.022
{"title":"Muscle Fatigability of Patients With Severe COPD and Chronic Respiratory Failure: The Contribution of Respiratory Factors","authors":"","doi":"10.1016/j.arbres.2024.05.022","DOIUrl":"10.1016/j.arbres.2024.05.022","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":null,"pages":null},"PeriodicalIF":8.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141454824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-01DOI: 10.1016/j.arbres.2024.04.012
{"title":"Sequential and Multimodal Bronchoscopic Interventions for COPD: Toward a Highly Personalized Interventional Pulmonology?","authors":"","doi":"10.1016/j.arbres.2024.04.012","DOIUrl":"10.1016/j.arbres.2024.04.012","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":null,"pages":null},"PeriodicalIF":8.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0300289624001200/pdfft?md5=0ce6b0aa70f60927f6f7434e9ab94882&pid=1-s2.0-S0300289624001200-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140784048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-01DOI: 10.1016/j.arbres.2024.05.023
{"title":"EBUS-Guided Transbronchial Mediastinal Cryobiopsy: A Novel Technique for Diagnosing Mediastinal Lesions—Single-Center Experience","authors":"","doi":"10.1016/j.arbres.2024.05.023","DOIUrl":"10.1016/j.arbres.2024.05.023","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":null,"pages":null},"PeriodicalIF":8.7,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141295481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号