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An Application to a Laboratory problem of Discriminant Function Analysis involving more than two Groups 两组以上判别函数分析在实验室问题中的应用
Pub Date : 1948-10-01 DOI: 10.1136/jech.2.4.139
R. Jennison, J. Penfold, J. Roberts
We have recently attempted to assess the value of a modification of the Wassermann reaction, based upon the suggestion of Richardson (1940). The results are being described in a pathological journal (Jennison, Penfold, and Roberts, 1949). The present paper deals with certain points which emerged during the statistical analysis, and which have a rather more general interest in regard to the application of statistical methods to biological data.
我们最近试图评估基于理查森(1940)的建议对瓦色尔曼反应进行修正的价值。研究结果发表在病理学杂志上(Jennison, Penfold, and Roberts, 1949)。本文讨论统计分析过程中出现的一些问题,这些问题对统计方法在生物数据中的应用具有相当普遍的意义。
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引用次数: 1
Sickness and Stress in Operational Flying 飞行中的疾病和压力
Pub Date : 1948-10-01 DOI: 10.1136/jech.2.4.123
D. Reid
To the medical branch of an air force, the social or environmental conditions of pressing importance are the psychological stresses inevitable in air warfare. Only in war is it possible to observe the effects of such factors as acute hazard and intensive operational effort, with their resultant anxiety and fatigue, on the performance and well-being of such a highly selected population as the air crews of the Royal Air Force. Both the immediate effects of these stresses on efficiency and the long-term results in health were, therefore, the urgent concern of those whose duty it was to minimize these effects by every means open to the medical branch of a combatant force. The central issue was one of limitation of spells of duty?either short term, where the effects of hours of prolonged attention were to be forestalled, or long term, where the limits of an operational tour had to be set at a level high enough to ensure an adequate operational return for the training investment made yet not so long as to endanger health and morale. The problems of peacetime practice in social and industrial medicine are hardly as dramatic,, yet the essential mechanism of the adjustment of men to the less hazardous but frequently harassing conditions of post-war life are identical. This account of some typical studies of sickness in relation to measurable environmental and personal factors is given in the hope oT displaying the potentialities of the methods used in the study of problems of sickness and morale in an industrial population. Research on duty limitation in the R.A.F. during the war had a tripartite approach by clinical, laboratory, and field surveys. The clinical studies have been described by Symonds (1943), the laboratory work by Russell Davis (1948); in the present paper is set out an application of statistical methods to data collected in the course of active operations in the field.
对于空军的医疗部门来说,具有迫切重要性的社会或环境条件是空战中不可避免的心理压力。只有在战争中,才有可能观察到急性危险和密集的作战努力等因素,以及由此产生的焦虑和疲劳,对皇家空军机组人员这样一个经过精心挑选的人群的表现和福祉的影响。因此,这些压力对效率的直接影响和对健康的长期影响都是那些职责是通过战斗部队医务部门可用的一切手段尽量减少这些影响的人迫切关注的问题。核心问题是义务的限制?要么是短期的,在这种情况下,要预先防止长时间关注的影响;要么是长期的,在这种情况下,必须将一次业务旅行的限制设定在足够高的水平,以确保所作的培训投资获得足够的业务回报,但又不至于长到危及健康和士气。和平时期社会和工业医疗实践的问题几乎没有那么引人注目,然而,使人们适应不那么危险但经常令人烦恼的战后生活条件的基本机制是相同的。本文介绍了一些与可测量的环境和个人因素有关的典型疾病研究,希望能展示用于研究工业人口中疾病和士气问题的方法的潜力。战时英国皇家空军的职责限制研究有临床、实验室和实地调查三方面的方法。临床研究由Symonds(1943)描述,实验室工作由Russell Davis(1948)描述;本文阐述了统计方法在实地积极作业过程中收集的数据中的应用。
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引用次数: 11
The Statistical Specificity of a Code Personnel Cypher Sequence 编码人员密码序列的统计特异性
Pub Date : 1948-10-01 DOI: 10.1136/JECH.2.4.149
L. Hogben, K. W. Cross
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引用次数: 5
Disorders of Sex and Reproduction 性与生殖障碍
Pub Date : 1948-10-01 DOI: 10.1136/JECH.2.4.155
F. Crew
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引用次数: 0
The Gerontological Aspects of Atheroma 动脉粥样硬化的老年学方面
Pub Date : 1948-10-01 DOI: 10.1136/jech.2.4.132
E. Geiringer
We may, as a matter of convenience, distinguish two categories of gerontological research, the study of old age or old people on the one hand, and the study of ageing on the other. Almost the whole of pathology is our field in the study of old age; for whilst there are very few diseases which spare the aged, many present special features when occurring in them, either attacking them more readily or being more dangerous and less tractable. The study of these phenomena presents a vast and important task, in which, however, orthodox pathology can be of great help. In the study of ageing the field is much narrower and the guidance to be derived from existing disciplines much less. Each one of the diseases of old age is characterized by the fact that it attacks individuals or groups of individuals, leaving a significant proportion of mankind untouched. These diseases are, however, only the superimposed complications of an under lying process of functional deterioration in which all human beings share, and it is with this universal process that we are concerned in the study of ageing. It must be admitted that strict proof for the existence of such a separate process of ageing is lacking. The concept that we are all subject to an identical processor complex of processes of deterior ation is based on purely circumstantial evidence and on an impression which has been prevailing in the human race throughout the centuries. But if, as a working hypothesis, we accept the existence of ageing as a separate physiological or pathological entity and begin to look round for its manifestations, we are struck by the extraordinary difficulty of finding them. In order to be acceptable as a part of the complex of senescence a phenomenon must fulfil at least two conditions: it must be exhibited by all the members of the species, and it must be demonstrable at a time at which the complications of old age are still rare. Atheroma of the aorta is one of the very few * Whaitt Research Scholar. co ditions which not only passes the test of both t se criteria but also furnishes us with easily accessible and comparatively easily measurable lesions. An analysis of aortic atheroma might, therefore, apart from its intrinsic interest, contribute to our understanding of the process of senescence.
为了方便起见,我们可以把老年学研究分为两类,一类是对老年或老年人的研究,另一类是对衰老的研究。几乎整个病理学都是我们研究老年的领域;因为,虽然很少有疾病能使老年人幸免,但许多疾病在老年人身上发生时却表现出一些特点,要么更容易攻击他们,要么更危险,更难以控制。这些现象的研究提出了一个巨大的和重要的任务,其中,然而,正统的病理学可以有很大的帮助。在老龄化的研究中,这个领域要狭窄得多,从现有学科中获得的指导要少得多。每一种老年疾病的特点都是攻击个人或群体,使很大一部分人不受影响。然而,这些疾病只是所有人类共同经历的一个潜在的功能退化过程的叠加并发症,我们在研究衰老时所关注的正是这个普遍的过程。必须承认,这种单独的衰老过程存在的严格证据是缺乏的。我们所有人都受到同一种复杂的退化过程的影响,这一概念纯粹是基于间接证据和几个世纪以来在人类中普遍存在的一种印象。但是,如果作为一种可行的假设,我们接受衰老作为一种独立的生理或病理实体的存在,并开始寻找它的表现形式,我们就会被找到它们的异常困难所震惊。一种现象要被认为是衰老复合体的一部分,必须至少满足两个条件:它必须为该物种的所有成员所展示,并且必须在老年并发症仍然罕见的时候被证明。主动脉粥样硬化是一种非常罕见的* Whaitt学者研究。这些条件不仅通过了这两个标准的测试,而且为我们提供了容易接近和相对容易测量的病变。主动脉粥样硬化的分析,因此,除了其内在的利益,有助于我们对衰老过程的理解。
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引用次数: 1
American medical services. 美国医疗服务。
Pub Date : 1948-07-01 DOI: 10.1136/jech.2.3.77
T McKEOWN
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引用次数: 3
The significance of nuptiality with respect to interpretation of sex differences. 婚姻在解释性别差异方面的重要性。
Pub Date : 1948-07-01 DOI: 10.1136/jech.2.3.106
M M JOHNSTONE, M E HOSKER
Existence of sex differentials with respect to disease in human populations is a matter which deserves investigation both from a practical and from a theoretical viewpoint. At the operational level, their interest scarcely calls for comment; but the biological significance we attach to them is an issue we are prone to dismiss too lightly by undue reliance on experience of laboratory stocks. In one way or another, most human societies are polarized with respect to the prevailing pattern of occupation in which one or other sex is engaged. Hence statistical regularities characteristic of the sex difference may well arise in virtue of hazards peculiar to different occupations in contradistinction to agencies ultimately traceable to the X-chromosome complement. If a wholly decisive test for discrimination between these possibilities or for evaluation of their relative importance in a given situation is not available, there is at least one framework of com parison relevant to a balanced judgment. On the whole, single females, if adult, have gainful employ ment outside the home, as do the majority of men. To this extent, we are entitled to expect that sex differences, if attributable to differential occupational risk, will be less obtrusive if we restrict our com parison to unmarried women. This does not mean that a sex differential attributable wholly or largely to circumstances unconnected with constitutional differences will disappear if we confine our compari son to men as a whole and to single women only. We must not disregard the fact that single women and men, if gainfully employed, dominate different trades and professions. For instance, men dominate the heavy industries and single women predominate in domestic and cognate services, including the care of children and the sick. It is none the less broadly true that the daily regime of the single woman conforms more to that of the male than does that of the married woman. In so far as the morbidity experience of the single woman conforms more to the male pattern we have therefore good grounds for assuming that differences which distinguish women as a whole are appreciably attributable to occupational status. The converse is not true, inasmuch as a difference which distin guishes the sexes may be associated with an occupa tional hazard almost or wholly restricted to males. Needless to say any comparison undertaken with this end in view is liable to lead us grossly astray if we do not pay attention to the differential incidence of disease with respect to age. Accordingly, comparisons of the mortality experience of men with that of women, or of single women with that of married women should take within their scope a breakdown with regard to age of the relevant populations at risk. This communication is an exam ination of what materials official statistics of disease supply. 2. Sources of Figures
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引用次数: 0
PRINCIPLES OF MEDICAL STATISTICS 医学统计原理
Pub Date : 1948-07-01 DOI: 10.1136/oem.5.3.161-b
Norman L. Munn
Dr. Munn is a lecturer in Psychology in Tennessee. He has written a book indicating the foundations of the lectures which he gives, and a remarkably full book it is, ranging from Plato to Rorschach. It moves through the problems of feeling, emotion, cognition, and achievement to those of intelligence and personality. The emphasis is throughout upon the experimental method of the psychological laboratory, and diagrams and figures are abundant. Every chapter is followed by a bibliography. The material presented is considerable, but it is all "potted." The small reproduction of Healy's picturecompletion test in Fig. 203 seems valueless as it stands, and similar criticisms could be levelled at many other figures. Where Dr. Munn is discussing introversion and extroversion he again inserts a figure which is interesting, but he does not in the text really tackle the problems involved. This is typical of the information given: it is true up to a point, but it is doubtful if any student could rely satisfactorily upon learning any useful psychology from this volume alone. The mischief is that many students would consider that they could. We have no doubt that Dr. Munn knows these dangers better than the reviewer. This book reminds us of those medical primers " Aids to... " which are so compressed that at times they give information which could be falsely interpreted. So long as Dr. Munn's book is recognized as an attempt to abbreviate an enormous subject and to stimulate further reading, well and good. But its danger lies in its being accepted too glibly as authoritative per se, and the simplicity of some of its diagrams illustrates these dangers only too well. As a form of suggestive notes to the teacher of psychology already well versed in the subject it has something useful to offer. H.W.
穆恩博士是田纳西州的心理学讲师。他写了一本书,说明了他讲课的基础,这是一本非常完整的书,从柏拉图到罗夏。它从感觉、情感、认知和成就的问题转移到智力和个性的问题。本书的重点贯穿于心理学实验室的实验方法,并且有大量的图表和图表。每章后面都附有参考书目。所呈现的材料是相当可观的,但它都是“盆栽”。图203中希利的图片完成测试的小复制品看起来毫无价值,类似的批评也可以针对许多其他数据。在Munn博士讨论内向和外向的地方他又插入了一个有趣的数字,但他并没有在文中真正解决相关的问题。这是所提供的典型信息:在某种程度上是正确的,但令人怀疑的是,是否有任何学生能够满意地依靠从这本书中学习任何有用的心理学。问题在于,许多学生会认为他们可以。毫无疑问,穆恩博士比审稿人更了解这些危险。这本书让我们想起了那些医学入门读物“帮助……”“这些信息被压缩得如此之快,以至于有时它们提供的信息可能会被错误地解读。只要穆恩博士的书被认为是在试图简化一个庞大的主题,并激发人们进一步阅读,那就再好不过了。但它的危险在于,它被过于轻率地当作本身的权威来接受,其中一些图表的简单性很好地说明了这些危险。作为一种提示性笔记的形式,对于已经精通这门学科的心理学教师来说,它有一些有用的东西。H.W.
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引用次数: 711
Returns of Sickness from Ships of the Royal Navy (1945-46); A Contribution to Medical Climatology * 英国皇家海军船只的疾病报告(1945- 1946);医学气候学的贡献*
Pub Date : 1948-04-01 DOI: 10.1136/jech.2.2.55
J. Roberts
A new short-term summary sickness return was instituted in the Royal Navy in July, 1945. The Admiralty Fleet Order calling for the new return is appended and explains its purpose and mechanism (Appendix). It was limited to ships carrying a medical officer and did not apply to shore establish ments or hospital ships. The primary purpose was the collection of statistics that would have a bearing on questions of habitability. For the first time the attempt was made to utilize minor sickness, and so the return called for counts of those on the Attending List as well as those on the Sick List and those discharged to hospital. It was anticipated that Attending List figures might perhaps prove a better index of living conditions than more serious illness necessitating absence from duty. Ships offer special advantages for this type of study. They bear a self-contained community with a relatively stable population. Changes in person nel are relatively small and gradual over considerable periods. The numbers at risk can be stated with accuracy. Such factors as changes in climatic conditions and differences in ship design can be readily studied in regard to their influence on fitness.
1945年7月,英国皇家海军设立了一项新的短期病休单。英国海军部舰队命令要求新的回归,并解释了其目的和机制(附录)。它仅限于载有一名医务人员的船舶,而不适用于岸上设施或医院船。主要目的是收集与可居住性问题有关的统计数据。这是第一次尝试利用小病,因此报告要求清点在护理名单上的人、在生病名单上的人和出院的人。人们预期,出席名单的数字可能证明是生活条件的一个更好的指标,而不是更严重的疾病需要缺勤。船舶为这类研究提供了特殊的优势。它们是一个人口相对稳定的自给自足的社区。人事变动相对较小,在相当长的时期内是渐进的。有风险的数字可以准确地说出来。气候条件的变化和船舶设计的差异等因素对适合度的影响可以很容易地进行研究。
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引用次数: 4
The Social Medicine of Old Age: Report of an Inquiry in Wolverhampton 老年社会医学:伍尔弗汉普顿调查报告
Pub Date : 1948-04-01 DOI: 10.1136/JECH.2.2.75
F. Crew
Dr. Sheldon puts it. For this reason it is deplorable that, in common with other recent investigators, he has not found it possible to emancipate himself from the use of the term "normal." It is absurd that in a survey which represents a beginning towards an effort to find the normal standards of ageing, individuals should straightway be divided into normal, super-normal, and sub-normal for their age. The plea that this was done on common-sense grounds seems rather strange. Altogether such few conclusions and speculations as there are in this book are inclined to be expressions of what is commonly known as common sense. Our old friend " wear and tear " is also met with in the pages of this book. If authors dealing with old age would begin to pay tribute to their own ignorance by foregoing the use of such biologically meaningless metaphors they Wvould help to clear the path for the acquisition of some real knowledge. Such criticism, however, concerns only the analytic parts of this book, the main part of which is devoted to an orderly account of the facts which emerged from an investigation extending over two years, in the course of which the social pattern of the lives of a 1: 30 random sample of the old people of Wolverhampton and the functioning of their minds and bodies were scrutinizedand studied with the help of a detailed questionnaire. The medical part of the investigation had to be restricted to the taking of histories, but the limitations arising from this and other difficulties are clearly realized by the author, who has made allowance for them in presenting his results. The scope of the survey is very wide indeed. After giving an account of the physical state of the subjects concerned and of the main physical symptoms complained of by them, the author goes on to deal in a similar manner with their mental state, the social structure of their homes, and the problems arising from illness in these old people. The author explodes some popular misconceptions and applies the corrective of exact recording to many vaguely held notions on the subject of old age. The main impression which he manages to convey is that old people are on the whole less handicapped than our clinical experience would tend to make us think. This book, packed with facts set down by a competent and sympathetic observer, should be read by gerontologists, social workers, and administrative planners alike. Theirs is the task of filling in the details, and they will be better fitted to do so after having studied this outline of the complete physical and social status of a typical sample of old people. F. A. E. CREw.
谢尔登博士说。由于这个原因,令人遗憾的是,与其他最近的研究者一样,他没有发现有可能从“正常”一词的使用中解放出来。荒谬的是,在一项代表着努力寻找正常衰老标准的开始的调查中,个人应该根据他们的年龄直接分为正常、超正常和次正常。声称这是基于常识的辩解似乎相当奇怪。总之,这本书中如此少的结论和推测都倾向于表达通常被称为常识的东西。我们的老朋友“磨损”也出现在这本书的页面上。如果作家们在处理老年问题时能开始通过放弃使用这些生物学上毫无意义的隐喻来向自己的无知致敬,他们将有助于为获得一些真正的知识扫清道路。然而,这样的批评只涉及本书的分析部分,本书的主要部分致力于有序地叙述从一项为期两年的调查中得出的事实,在此过程中,在一份详细的问卷调查的帮助下,对伍尔弗汉普顿的1:30随机抽样的老年人的社会生活模式及其身心功能进行了仔细检查和研究。调查的医疗部分必须限于记录病史,但提交人清楚地认识到这方面和其他困难所造成的限制,他在提交结果时考虑到了这些限制。调查的范围确实很广。在叙述了有关老人的身体状况和他们所抱怨的主要身体症状之后,提交人接着以类似的方式论述了他们的精神状况、他们的家庭社会结构以及这些老人的疾病所引起的问题。作者破除了一些普遍存在的误解,用准确记录的方法纠正了许多关于老年的模糊观念。他设法传达的主要印象是,老年人总的来说并不像我们的临床经验往往使我们认为的那样残疾。这本书中充满了一位称职而富有同情心的观察者所记录的事实,老年学家、社会工作者和行政规划人员都应该阅读。他们的任务是填补细节,在研究了一个典型老年人的完整身体和社会地位的轮廓之后,他们将更适合这样做。空勤人员。
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引用次数: 12
期刊
British journal of social medicine
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