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Laparoscopic Intra-Ovarian Platelet Rich Plasma Injection for Ovarian Rejuvenation 腹腔镜卵巢内富血小板血浆注射用于卵巢年轻化
Pub Date : 2023-06-29 DOI: 10.21608/bjas.2023.221365.1201
Mohamed Elsherbiny, Mohamed Mohamed, Sahar Abdellatif, Waleed Tawfik
Background: Ovarian failure, characterized by the loss of ovarian function, presents a significant challenge for women seeking to conceive. Conventional treatments have limitations in restoring ovarian function and fertility. Platelet-rich plasma (PRP) therapy has emerged as a potential regenerative approach for ovarian rejuvenation. The aim of this study was to assess the influence of intraovarian injection of PRP on ovarian function in a case with ovarian failure. Methods: This prospective interventional multi-center study included 50 women with primary and secondary ovarian failure selected from Obstetrics and Gynecology Department, Benha University Hospitals & other private centers. All patients were subjected to complete history taking, clinical examination, laboratory investigations including hormonal Laboratory evaluation of (FSH, LH, estradiol, AMH), PRP injection under intravenous anesthesia and post-operative follow up mainly for measuring ovarian hormones: FSH, LH, AMH, E2 every month for 6 months. Results: The current study included 50 patients. The mean age of them was (36.68 ± 6.36 years); range from (24 –45years). The median age (Q1, Q3) was 38 (32.75, 42). The mean serum follicle stimulating hormone (FSH) was 38.82 ± 20.38 (range 7.03 to 90.2) and its median (Q1, Q2) was 36.75 (19.75, 57). The mean serum luteinizing hormone (LH) was 21.43 ± 14.36 (range 4.3 to 65.5) and its median (Q1, Q2) was 16.9 (11.3, 28.7). The mean serum Estradiol hormone (E2) was 29.87 ± 22.72 (range 5 to 96) and its median (Q1, Q2) was 22.16 (13.1, 38.25). Conclusions: In the study group, intraovarian injection of PRP decreased FSH, LH, and increased E2 levels significantly, however it was less effective for boosting AMH levels. At 6-month intervals, the readings reverted to levels comparable to those that existed before to the PRP therapy. Therefore, PRP may be used alone or in conjunction with hormone therapy to treat infertility in women with poor ovarian reserve. In future clinical therapeutics, it might be regarded a time-efficient and cost-effective therapy technique.
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引用次数: 0
Chronic Kidney Disease and its Effect on the lungs 慢性肾病及其对肺部的影响
Pub Date : 2023-06-29 DOI: 10.21608/bjas.2023.216929.1187
Mohamed Ibrahim, Tarek Essawy, Rehab Salah, Mohamed Abdelazeem Ali Ameesh
Background: Chronic kidney disease (CKD), which is also referred to as chronic renal disease, refers to the gradual deterioration of kidney function that occurs over several months or years. Anyone whose glomerular filtration rate (GFR) has been less than 60 mL/min/1.73 m2 for at least three months is diagnosed with chronic kidney disease, regardless of whether or not there is any kidney damage present. Aim and objectives: to study the effect of chronic kidney disease on the pulmonary system, Subjects and methods: The study was performed on 40 patients with chronic kidney disease at Faculty of Medicine – Benha University , Result: There was significant differences between two groups as regard CBC, urea, creatinine, K and uric acid. There was insignificant differences between two groups as regard D dimer. There was a statically significant correlation between PE max % predictive and duration of illness and dialysis , temperature , Sat.O2, FVC ,Hb,WBCs , PLTT, urea , creatinine , INR, K, , uric acid and albumin. Conclusion: Awareness of the interrelatedness of respiratory and renal function is important in managing patients with diseases of both the lungs and the kidneys.
背景:慢性肾脏病(CKD)又称慢性肾脏病,是指肾功能在数月或数年内逐渐衰退。任何肾小球滤过率(GFR)低于 60 毫升/分钟/1.73 平方米至少三个月的人都会被诊断为慢性肾脏病,无论是否存在肾脏损伤。目的和目标:研究慢性肾脏病对肺部系统的影响:研究对象是本哈大学医学院的 40 名慢性肾病患者:两组患者在全血细胞计数、尿素、肌酐、钾和尿酸方面存在明显差异。两组在 D 二聚体方面的差异不明显。PE 最大预测百分比与病程和透析时间、体温、Sat.O2、FVC、Hb、WBCs、PLTT、尿素、肌酐、INR、K、尿酸和白蛋白之间有统计学意义的相关性。结论认识到呼吸功能和肾功能之间的相互关系对于管理肺部和肾脏疾病患者非常重要。
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引用次数: 0
Doppler Evaluation of the Fetal Pulmonary Artery Pressure 多普勒评估胎儿肺动脉压力
Pub Date : 2023-06-29 DOI: 10.21608/bjas.2023.214064.1178
Mohamed Mohamed, Ahmed Sadek, Ibrahim Soudian, Amal Abdelgwad
Background: Evaluation of fetal pulmonary artery pressure (FMPAP) is important for assessing fetal cardiovascular function. Methods: A prospective study was conducted on 60 pregnant women between 22 and 40 weeks of gestation. Pulmonary Doppler examinations were performed at two time points during the second and third trimesters. Various Doppler variables, including the systolic/diastolic (S/D) ratio, pulsatility index (PI), resistance index (RI), peak systolic velocity (PSV), and At/Et ratio, were measured. Results: The mean values of the Doppler variables were determined. Significant differences were observed between the two examination time points, with higher values during the second visit. Negative correlations were found between these variables and both gestational age and fetal weight. Additionally, positive correlations were identified between the Doppler variables and neonatal intensive care unit (NICU) admission. Furthermore, the Doppler variables were significant predictors of both gestational age and fetal weight. Conclusions: Doppler velocimetry has been shown to be useful for detecting not just fetal pulmonary maturity, but also the FMPAP, and we expect that future research will demonstrate that estimations of the MFPAP may be able to predict whether or not the newborn will develop pulmonary hypertension.
背景:评估胎儿肺动脉压(FMPAP)对评估胎儿心血管功能非常重要。研究方法对妊娠 22 至 40 周的 60 名孕妇进行了前瞻性研究。在妊娠的第二和第三个三个月的两个时间点进行了肺多普勒检查。测量了各种多普勒变量,包括收缩/舒张(S/D)比值、搏动指数(PI)、阻力指数(RI)、收缩峰值速度(PSV)和 At/Et 比值。结果确定了多普勒变量的平均值。两次检查的时间点之间存在显著差异,第二次检查的数值更高。这些变量与胎龄和胎儿体重均呈负相关。此外,还发现多普勒变量与新生儿重症监护室(NICU)入院时间呈正相关。此外,多普勒变量对胎龄和胎儿体重都有显著的预测作用。结论多普勒测速仪已被证明不仅能检测胎儿肺成熟度,还能检测胎儿肺动脉瓣成熟度(FMPAP),我们期待未来的研究能证明,胎儿肺动脉瓣成熟度(MFPAP)的估算值或许能预测新生儿是否会出现肺动脉高压。
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引用次数: 0
Management of Pediatric Renal Stones (10-20mm) by Flexible Ureteroscopy (F-URS), Miniaturized Percutaneous Nephrolithotomy (Mini-Perc) or Extracorporeal Shock Wave Lithotripsy (ESWL): Comparative Study 通过输尿管软镜(F-URS)、小型化经皮肾镜碎石术(Mini-Perc)或体外冲击波碎石术(ESWL)治疗小儿肾结石(10-20 毫米):比较研究
Pub Date : 2023-06-29 DOI: 10.21608/bjas.2023.215673.1185
Ahmed Abd El Naeem Ali El Mogy, Tarek Soliman Othman, Hussein Shaher, Mohamed Abd Elzaher, Salah Elhamshary
Background: Kidney stones have become much more common in recent years. Renal stones in children are often caused by congenital anatomical abnormalities, metabolic problems, or recurrent urinary tract infections. This is why padiatrics are more likely to have recurrent urolithiasis and need repeated surgical procedures. Methods: Subjects for this prospective trial, all of whom had a single renal stone (in the pelvis or lower calyx) measuring 10-20 mm in diameter, were collected and randomly assigned to one of three groups (A; F-URS; B; Mini-Perc; C) (ESWL). The flexible ureteroscope was used to complete the URS procedure. Stones in Groups A and B were fractured or dusted using holmium:YAG laser during mini-Perc, which was conducted using a rigid paediatric nephoscope. Under fluoroscopy's watchful eye, ESWL was carried out with the aid of a piezoelectric lithotripter machine. Results: No statistically significant variations in stone location, orientation, size, or density were found. There was a statistically significant difference in operative time between the three groups tested, with group B taking much longer than groups A and C. Group B had a considerably longer fluoroscopy duration compared to groups A and C. There were no noteworthy variations in blood loss or the need for ancillary procedures. Conclusions: Treatment of renal stones in children less than 16 years old with ESWL, mini-PCNL, or RIRS is safe and successful.
背景:近年来,肾结石越来越常见。儿童肾结石通常是由先天性解剖异常、代谢问题或反复尿路感染引起的。这就是为什么儿科患儿更容易反复患上尿路结石并需要反复进行手术治疗的原因。研究方法本次前瞻性试验的受试者均为单发肾结石(位于肾盂或下肾萼),直径为 10-20 毫米,受试者被收集并随机分配到三组中的一组(A;F-URS;B;Mini-Perc;C)(ESWL)。使用输尿管软镜完成 URS 手术。A 组和 B 组的结石在迷你手术中使用钬:YAG 激光碎石或除石,迷你手术使用硬质儿科肾镜进行。在透视监视下,借助压电碎石机进行 ESWL。结果:结石的位置、方向、大小或密度均无明显统计学差异。B 组的透视时间比 A 组和 C 组长得多。结论用 ESWL、迷你 PCNL 或 RIRS 治疗 16 岁以下儿童的肾结石是安全和成功的。
{"title":"Management of Pediatric Renal Stones (10-20mm) by Flexible Ureteroscopy (F-URS), Miniaturized Percutaneous Nephrolithotomy (Mini-Perc) or Extracorporeal Shock Wave Lithotripsy (ESWL): Comparative Study","authors":"Ahmed Abd El Naeem Ali El Mogy, Tarek Soliman Othman, Hussein Shaher, Mohamed Abd Elzaher, Salah Elhamshary","doi":"10.21608/bjas.2023.215673.1185","DOIUrl":"https://doi.org/10.21608/bjas.2023.215673.1185","url":null,"abstract":"Background: Kidney stones have become much more common in recent years. Renal stones in children are often caused by congenital anatomical abnormalities, metabolic problems, or recurrent urinary tract infections. This is why padiatrics are more likely to have recurrent urolithiasis and need repeated surgical procedures. Methods: Subjects for this prospective trial, all of whom had a single renal stone (in the pelvis or lower calyx) measuring 10-20 mm in diameter, were collected and randomly assigned to one of three groups (A; F-URS; B; Mini-Perc; C) (ESWL). The flexible ureteroscope was used to complete the URS procedure. Stones in Groups A and B were fractured or dusted using holmium:YAG laser during mini-Perc, which was conducted using a rigid paediatric nephoscope. Under fluoroscopy's watchful eye, ESWL was carried out with the aid of a piezoelectric lithotripter machine. Results: No statistically significant variations in stone location, orientation, size, or density were found. There was a statistically significant difference in operative time between the three groups tested, with group B taking much longer than groups A and C. Group B had a considerably longer fluoroscopy duration compared to groups A and C. There were no noteworthy variations in blood loss or the need for ancillary procedures. Conclusions: Treatment of renal stones in children less than 16 years old with ESWL, mini-PCNL, or RIRS is safe and successful.","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"99 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139367851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of Ischemia-Modified Albumin Level in Patients with Psoriasis Vulgaris 寻常型银屑病患者缺血修饰白蛋白水平的评估
Pub Date : 2023-06-29 DOI: 10.21608/bjas.2023.208485.1161
Ahmed Saleh, Mohamed Hussein, Hamasat Abdel-Khalik, Samar Al-Sharkawy
Background: Psoriasis is a chronic proliferative inflammatory cutaneous condition manifested by pathological cutaneous lesions caused by multiple external and internal causes. This research aims to evaluate the IMA serum levels in psoriasis vulgaris cases and compare with healthy controls. Methods: This case control research was performed on sixty male and female psoriasis vulgaris patients with age ≥ 18 years and tewnty age and sex matched healthy control. All patients underwent general examination, clinical examination of the psoriatic lesions and laboratory investigation for measurement of IMA serum level. PASI score was utilized for disease severity evaluation. Results: Age, gender, disease duration and PASI score were insignificantly different between the study groups. BMI was significantly different between the study groups (P < 0.001). BMI showed a significant difference between paired groups, group I & IV and group II & III (P < 0.001, P < 0.001; respectively). BMI was significantly lower in group I than group II (P < 0.001) and was significantly lower in group III than group IV (P < 0.001). Conclusions: Obesity is a common comorbidity with psoriasis which may worsen the disease progression by adding more ROS to the pathogenesis of psoriasis. Obese psoriatic patients were shown to have a greater IMA than non-obese psoriatic patients.
{"title":"Assessment of Ischemia-Modified Albumin Level in Patients with Psoriasis Vulgaris","authors":"Ahmed Saleh, Mohamed Hussein, Hamasat Abdel-Khalik, Samar Al-Sharkawy","doi":"10.21608/bjas.2023.208485.1161","DOIUrl":"https://doi.org/10.21608/bjas.2023.208485.1161","url":null,"abstract":"Background: Psoriasis is a chronic proliferative inflammatory cutaneous condition manifested by pathological cutaneous lesions caused by multiple external and internal causes. This research aims to evaluate the IMA serum levels in psoriasis vulgaris cases and compare with healthy controls. Methods: This case control research was performed on sixty male and female psoriasis vulgaris patients with age ≥ 18 years and tewnty age and sex matched healthy control. All patients underwent general examination, clinical examination of the psoriatic lesions and laboratory investigation for measurement of IMA serum level. PASI score was utilized for disease severity evaluation. Results: Age, gender, disease duration and PASI score were insignificantly different between the study groups. BMI was significantly different between the study groups (P < 0.001). BMI showed a significant difference between paired groups, group I & IV and group II & III (P < 0.001, P < 0.001; respectively). BMI was significantly lower in group I than group II (P < 0.001) and was significantly lower in group III than group IV (P < 0.001). Conclusions: Obesity is a common comorbidity with psoriasis which may worsen the disease progression by adding more ROS to the pathogenesis of psoriasis. Obese psoriatic patients were shown to have a greater IMA than non-obese psoriatic patients.","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135155443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pediculus Capitis :An overview 头蒂:综述
Pub Date : 2023-06-29 DOI: 10.21608/bjas.2023.211247.1171
Osama El Fady, Samah Ibrahim, Nagat Soliman, Asmaa Abdel Raouf
Background: The head louse, also known as Pediculus humanus capitis, is a parasitic insect that infects millions of people, primarily children, across the world. Lice infestations can cause severe health problems, including social and psychological repercussions. Objectives: This review provides an overview of Pediculus humanus capitis, including its prevalence, distribution, and transmission. In addition, we cover the biology and morphology of head lice, the epidemiology of head lice infestations, and the numerous diagnostic and treatment procedures. Finally, we examine ways for avoiding and treating head lice infestations, as well as the ramifications of this parasitic illness for public health. Conclusions: Infestations of head lice are a severe public health issue with considerable social and economic ramifications. To address this issue and enhance the health and well-being of individuals and communities, effective diagnosis and treatment, as well as preventative and control initiatives, are required.
{"title":"Pediculus Capitis :An overview","authors":"Osama El Fady, Samah Ibrahim, Nagat Soliman, Asmaa Abdel Raouf","doi":"10.21608/bjas.2023.211247.1171","DOIUrl":"https://doi.org/10.21608/bjas.2023.211247.1171","url":null,"abstract":"Background: The head louse, also known as Pediculus humanus capitis, is a parasitic insect that infects millions of people, primarily children, across the world. Lice infestations can cause severe health problems, including social and psychological repercussions. Objectives: This review provides an overview of Pediculus humanus capitis, including its prevalence, distribution, and transmission. In addition, we cover the biology and morphology of head lice, the epidemiology of head lice infestations, and the numerous diagnostic and treatment procedures. Finally, we examine ways for avoiding and treating head lice infestations, as well as the ramifications of this parasitic illness for public health. Conclusions: Infestations of head lice are a severe public health issue with considerable social and economic ramifications. To address this issue and enhance the health and well-being of individuals and communities, effective diagnosis and treatment, as well as preventative and control initiatives, are required.","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135155980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Fetal Lung Maturity Correlated by Various Ultrasound Parameters as Noninvasive Method 无创方法评价超声参数与胎儿肺成熟度的相关性
Pub Date : 2023-06-29 DOI: 10.21608/bjas.2023.215637.1183
Hisham El Sheikh, Mohamed Tawfiq, Nameer Fazaa
Background: Neonatal respiratory distress syndrome (RDS) continues to be a major problem in perinatology, contributing to the morbidity and death of preterm babies. To lower the risk of newborn RDS, the major objective of this study was to measure fetal lung maturity utilizing various color Doppler and multiple ultrasonography characteristics. Methods: This research was conducted on a cohort of 100 pregnant women who gave birth at Benha University Hospitals between February 26, 2022 and August 25, 2022, spanning six months. According to the occurrence of RDS, we categorized our study subjects into two groups: Group RDS+: n = 13; group RDS-: n = 87. Regarding (Maternal age, Parity, Type of delivery), there was no statistically significant difference between the two groups, but there was a statistically significant difference between the two groups regarding (Gestational age at Birth and NBW). Results: According to ultrasonography measurements, the Mann-Whitney test revealed no significant changes in the main pulmonary artery diameter (MPA), trans cerebellar diameter, or placental thickness between the study groups. The chi-square test revealed significant differences between proximal tibial epiphysis and thalamic echogenicity (p 0.001). Positive PTE results were seen in 91.95 percent of the non-RDS group compared to 7.69 percent of the RDS group. Thalamic echogenicity was seen in 88.5% of the non-RDS group compared to 15.38% of the RDS group. Conclusions: The development of newborn RDS may be accurately predicted using certain acoustic characteristics. The ultrasonic identification of the proximal tibial ossification sites and thalamic echogenicity demonstrated the highest accuracy in predicting fetal lung maturity.
{"title":"Evaluation of Fetal Lung Maturity Correlated by Various Ultrasound Parameters as Noninvasive Method","authors":"Hisham El Sheikh, Mohamed Tawfiq, Nameer Fazaa","doi":"10.21608/bjas.2023.215637.1183","DOIUrl":"https://doi.org/10.21608/bjas.2023.215637.1183","url":null,"abstract":"Background: Neonatal respiratory distress syndrome (RDS) continues to be a major problem in perinatology, contributing to the morbidity and death of preterm babies. To lower the risk of newborn RDS, the major objective of this study was to measure fetal lung maturity utilizing various color Doppler and multiple ultrasonography characteristics. Methods: This research was conducted on a cohort of 100 pregnant women who gave birth at Benha University Hospitals between February 26, 2022 and August 25, 2022, spanning six months. According to the occurrence of RDS, we categorized our study subjects into two groups: Group RDS+: n = 13; group RDS-: n = 87. Regarding (Maternal age, Parity, Type of delivery), there was no statistically significant difference between the two groups, but there was a statistically significant difference between the two groups regarding (Gestational age at Birth and NBW). Results: According to ultrasonography measurements, the Mann-Whitney test revealed no significant changes in the main pulmonary artery diameter (MPA), trans cerebellar diameter, or placental thickness between the study groups. The chi-square test revealed significant differences between proximal tibial epiphysis and thalamic echogenicity (p 0.001). Positive PTE results were seen in 91.95 percent of the non-RDS group compared to 7.69 percent of the RDS group. Thalamic echogenicity was seen in 88.5% of the non-RDS group compared to 15.38% of the RDS group. Conclusions: The development of newborn RDS may be accurately predicted using certain acoustic characteristics. The ultrasonic identification of the proximal tibial ossification sites and thalamic echogenicity demonstrated the highest accuracy in predicting fetal lung maturity.","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135155979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Growth Differentiation Factor-15 in psoriatic patients: a narrative review 银屑病患者生长分化因子-15的研究综述
Pub Date : 2023-06-29 DOI: 10.21608/bjas.2023.212060.1173
Essam El-Sayed Akl, Maram Farh, nehad fouad, karem IBRAHIM
Background: Protein biomarkers in the bloodstream have the potential to aid in diagnosis, evaluate prognosis, and direct treatment. Multiple CV events have been linked to Growth Differentiation Factor 15, a cytokine released in response to cellular stress and inflammation. Psoriasis has been linked to cardiovascular disease, however the significance of this association is unclear. Objectives: Growth Differentiation Factor-15 (GDF-15) is being studied for its potential function in psoriasis. Data Sources: By searching and reviewing Medline databases (Pub Med and Medscape) and the role of GDF-15 in psoriasis available till 2022. Study Selection: The quality of each study was evaluated separately before inclusion. If they met any of the following criteria, we considered them for inclusion: 1. It is written and published in English. (2) Featured in reputable, academic publications. Third, explain why GDF-15 is so important for psoriasis sufferers.. Data Extraction: There was a process of excluding studies that did not meet the inclusion criteria. Ethical permission, eligibility criteria, controls, information, and well-defined evaluation measures were all factors in determining the study's quality. Information relevant to our interested research outcomes was independently retrieved from each qualifying study utilising a data collecting form. Conclusions: We may infer that GDF-15's inflammatory actions may contribute to the aetiology and severity of psoriasis.
{"title":"Growth Differentiation Factor-15 in psoriatic patients: a narrative review","authors":"Essam El-Sayed Akl, Maram Farh, nehad fouad, karem IBRAHIM","doi":"10.21608/bjas.2023.212060.1173","DOIUrl":"https://doi.org/10.21608/bjas.2023.212060.1173","url":null,"abstract":"Background: Protein biomarkers in the bloodstream have the potential to aid in diagnosis, evaluate prognosis, and direct treatment. Multiple CV events have been linked to Growth Differentiation Factor 15, a cytokine released in response to cellular stress and inflammation. Psoriasis has been linked to cardiovascular disease, however the significance of this association is unclear. Objectives: Growth Differentiation Factor-15 (GDF-15) is being studied for its potential function in psoriasis. Data Sources: By searching and reviewing Medline databases (Pub Med and Medscape) and the role of GDF-15 in psoriasis available till 2022. Study Selection: The quality of each study was evaluated separately before inclusion. If they met any of the following criteria, we considered them for inclusion: 1. It is written and published in English. (2) Featured in reputable, academic publications. Third, explain why GDF-15 is so important for psoriasis sufferers.. Data Extraction: There was a process of excluding studies that did not meet the inclusion criteria. Ethical permission, eligibility criteria, controls, information, and well-defined evaluation measures were all factors in determining the study's quality. Information relevant to our interested research outcomes was independently retrieved from each qualifying study utilising a data collecting form. Conclusions: We may infer that GDF-15's inflammatory actions may contribute to the aetiology and severity of psoriasis.","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135155977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serum Interleukin 17 in Patients with Pattern Hair Loss 模式性脱发患者的血清白细胞介素 17
Pub Date : 2023-06-29 DOI: 10.21608/bjas.2023.212888.1174
Sherine Ahmed, G.M .Abdel Khalik, Amira Abd El-Ghafar, Yasmin Mohammed
Objectives: Evaluation of serum interleukin-17 in female-pattern baldness. Background: The top and frontal regions of the scalp are the most vulnerable to pattern baldness. Although interleukin-17 has many important biological roles, those associated with inflammation are the most well studied. Data sources: By searching and reviewing Medline databases (Pub Med and Medscape) and the role of serum interleukin 17 level in pattern hair loss available till 2023. Study selection: The quality of each study was evaluated separately before inclusion. The following requirements were met for inclusion: Publications in English that examine the significance of serum interleukin 17 level in the aetiology of pattern hair loss from a peer-reviewed publication. Data extraction: Studies were not included if they did not meet the inclusion criteria. The quality of a study may be determined by checking its ethical approval, eligibility criteria, controls, information, and evaluation methods. Information relevant to our interested research outcomes was independently retrieved from each qualifying study utilising a data collecting form. Conclusion: It's reasonable to say that IL-17 is involved in the aetiology of balding patterns.
目的评估女性斑秃患者的血清白细胞介素-17。背景:头皮的顶部和前额是最容易发生斑秃的部位。尽管白细胞介素-17 有许多重要的生物学作用,但与炎症相关的作用研究得最多。数据来源:通过搜索和查阅 Medline 数据库(Pub Med 和 Medscape)以及 2023 年之前的血清白细胞介素 17 水平在模式性脱发中的作用。研究选择:在纳入研究之前,对每项研究的质量进行了单独评估。纳入研究需满足以下要求:同行评议出版物中研究血清白细胞介素 17 水平在脱发病因学中重要性的英文出版物。数据提取:不符合纳入标准的研究不予纳入。一项研究的质量可通过检查其伦理批准、资格标准、对照、信息和评估方法来确定。与我们感兴趣的研究成果相关的信息是利用数据收集表从每项合格的研究中独立提取的。结论可以合理地说,IL-17 参与了秃顶模式的病因学研究。
{"title":"Serum Interleukin 17 in Patients with Pattern Hair Loss","authors":"Sherine Ahmed, G.M .Abdel Khalik, Amira Abd El-Ghafar, Yasmin Mohammed","doi":"10.21608/bjas.2023.212888.1174","DOIUrl":"https://doi.org/10.21608/bjas.2023.212888.1174","url":null,"abstract":"Objectives: Evaluation of serum interleukin-17 in female-pattern baldness. Background: The top and frontal regions of the scalp are the most vulnerable to pattern baldness. Although interleukin-17 has many important biological roles, those associated with inflammation are the most well studied. Data sources: By searching and reviewing Medline databases (Pub Med and Medscape) and the role of serum interleukin 17 level in pattern hair loss available till 2023. Study selection: The quality of each study was evaluated separately before inclusion. The following requirements were met for inclusion: Publications in English that examine the significance of serum interleukin 17 level in the aetiology of pattern hair loss from a peer-reviewed publication. Data extraction: Studies were not included if they did not meet the inclusion criteria. The quality of a study may be determined by checking its ethical approval, eligibility criteria, controls, information, and evaluation methods. Information relevant to our interested research outcomes was independently retrieved from each qualifying study utilising a data collecting form. Conclusion: It's reasonable to say that IL-17 is involved in the aetiology of balding patterns.","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139367960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of changing the focus size of piezoelectric lithotripsy on renal stone disintegration: A prospective randomized study 改变压电碎石焦点大小对肾结石崩解的影响:一项前瞻性随机研究
Pub Date : 2023-06-28 DOI: 10.21608/bjas.2023.210177.1169
Salah El Hamshary, Tarek El-Karamany, Shabib Mohamed, Mostafa Elsayed, Hosam Abu El-Nasr
The purpose of this study is to evaluate the efficacy of different focus sizes used in shock wave lithotripsy (SWL) in breaking up renal stones. Methods One hundred patients with radio-opaque renal stones up to 20 mm were included in this prospective trial from the urology department at Benha University Hospital. Patients were divided into two groups at random. Group A was overseen by F1 and Group B by F2.KUB determined the percentage of patients who were stone-free after two weeks. There were no statistically significant differences between groups with respect to loin pain (P = 0.121), loin pain duration (P = 0.963), stone size (P = 0.443), stone density (P = 0.6), stone number (P = 0.897), stone location, or hydronephrosis (P = 1.01).Stones were most often found in the left lower calyx (28%) of patients in group A, and the left mid-calyx (38% of patients in group B). Two-week residual (P = 0.024), residual size (P = 0.049), and stone-free rate (P = 0.033) all differed significantly across the groups. In terms of adverse effects, group B had a substantially greater incidence of both colic (22% vs. 10%, P = 0.027) and fever (20% vs. 6%, P = 0.034). In terms of hematuria, no significant changes were found (P = 0.239). A high stone-free rate can be achieved with a small focus size and a constant force and rate in SWL, but these findings need to be validated in the presence of other variables, such as breathing or stone movement, which can influence effectiveness.
{"title":"The impact of changing the focus size of piezoelectric lithotripsy on renal stone disintegration: A prospective randomized study","authors":"Salah El Hamshary, Tarek El-Karamany, Shabib Mohamed, Mostafa Elsayed, Hosam Abu El-Nasr","doi":"10.21608/bjas.2023.210177.1169","DOIUrl":"https://doi.org/10.21608/bjas.2023.210177.1169","url":null,"abstract":"The purpose of this study is to evaluate the efficacy of different focus sizes used in shock wave lithotripsy (SWL) in breaking up renal stones. Methods One hundred patients with radio-opaque renal stones up to 20 mm were included in this prospective trial from the urology department at Benha University Hospital. Patients were divided into two groups at random. Group A was overseen by F1 and Group B by F2.KUB determined the percentage of patients who were stone-free after two weeks. There were no statistically significant differences between groups with respect to loin pain (P = 0.121), loin pain duration (P = 0.963), stone size (P = 0.443), stone density (P = 0.6), stone number (P = 0.897), stone location, or hydronephrosis (P = 1.01).Stones were most often found in the left lower calyx (28%) of patients in group A, and the left mid-calyx (38% of patients in group B). Two-week residual (P = 0.024), residual size (P = 0.049), and stone-free rate (P = 0.033) all differed significantly across the groups. In terms of adverse effects, group B had a substantially greater incidence of both colic (22% vs. 10%, P = 0.027) and fever (20% vs. 6%, P = 0.034). In terms of hematuria, no significant changes were found (P = 0.239). A high stone-free rate can be achieved with a small focus size and a constant force and rate in SWL, but these findings need to be validated in the presence of other variables, such as breathing or stone movement, which can influence effectiveness.","PeriodicalId":8745,"journal":{"name":"Benha Journal of Applied Sciences","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135359662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Benha Journal of Applied Sciences
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