Pub Date : 2017-03-03DOI: 10.19080/APBIJ.2017.01.555569
Raju Panta
Many faculty members in medical schools encourage their students to attend classes regularly emphasizing that regular class attendance facilitates learning and enhances their performance in examinations. Class attendance appears to be a better predictor of college grades than any other known predictor of college grades including Scholastic Assessment Test (SAT) scores, High School Grade Point Average (HSGPA), studying skills, and the amount of time spent studying [1]. The efforts to increase the class attendance rates among college students helped to achieve dramatic improvements in average grades [2].
{"title":"Class Attendance and the Performances in Physiology Board Examinations: A Study in a Caribbean Medical School","authors":"Raju Panta","doi":"10.19080/APBIJ.2017.01.555569","DOIUrl":"https://doi.org/10.19080/APBIJ.2017.01.555569","url":null,"abstract":"Many faculty members in medical schools encourage their students to attend classes regularly emphasizing that regular class attendance facilitates learning and enhances their performance in examinations. Class attendance appears to be a better predictor of college grades than any other known predictor of college grades including Scholastic Assessment Test (SAT) scores, High School Grade Point Average (HSGPA), studying skills, and the amount of time spent studying [1]. The efforts to increase the class attendance rates among college students helped to achieve dramatic improvements in average grades [2].","PeriodicalId":8778,"journal":{"name":"Biochemistry international","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77794775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-02-27DOI: 10.19080/APBIJ.2017.01.555568
Dr Sabita Yograj
We have progressed in the modern world making our lives comfortable with the help of industrialisation, urbanisation, and globalisation, social and economic developments. These plethoras of events have led to rapid alterations in diets and lifestyles like inappropriate diet, poor quality of nutrition, lack of physical activity and much other behaviour known to be detrimental to health. Thus, large population of people have poor health because of the increased incidences of diseases like obesity, metabolic syndrome, diabetes, cardiovascular diseases, polycystic ovarian disease, allergies of different sorts and some types of cancers. Living a healthy life is a challenge for all of us in the modern day world as we are always being threatened by several degenerate lifestyle diseases. Indigenous populations tradionally used natural products to treat a broad range of diseases and ailments [1,2].
{"title":"Flaxseed- A Shield against Diseases?","authors":"Dr Sabita Yograj","doi":"10.19080/APBIJ.2017.01.555568","DOIUrl":"https://doi.org/10.19080/APBIJ.2017.01.555568","url":null,"abstract":"We have progressed in the modern world making our lives comfortable with the help of industrialisation, urbanisation, and globalisation, social and economic developments. These plethoras of events have led to rapid alterations in diets and lifestyles like inappropriate diet, poor quality of nutrition, lack of physical activity and much other behaviour known to be detrimental to health. Thus, large population of people have poor health because of the increased incidences of diseases like obesity, metabolic syndrome, diabetes, cardiovascular diseases, polycystic ovarian disease, allergies of different sorts and some types of cancers. Living a healthy life is a challenge for all of us in the modern day world as we are always being threatened by several degenerate lifestyle diseases. Indigenous populations tradionally used natural products to treat a broad range of diseases and ailments [1,2].","PeriodicalId":8778,"journal":{"name":"Biochemistry international","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84489547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-02-20DOI: 10.19080/APBIJ.2017.01.555566
Sandip H. Shah
Although it is agreed that anatomy is the language of medicine, the 21st century medical curriculum has often shown to reduce the hours dedicated towards anatomy education. A medical school therefore should reevaluate its own curriculum what the students need to learn. Since anatomy is exposed to the students at the outset of a curriculum [1], medical schools, therefore, should be careful in planning students-directed anatomy objectives and how they are going to be delivered. This is important as the current pressure to reduce the hours devoted to learning anatomy may even complicate the entire planning [2,3].
{"title":"Anatomy Education in MBBS: Nepal’s Perspective and Challenges","authors":"Sandip H. Shah","doi":"10.19080/APBIJ.2017.01.555566","DOIUrl":"https://doi.org/10.19080/APBIJ.2017.01.555566","url":null,"abstract":"Although it is agreed that anatomy is the language of medicine, the 21st century medical curriculum has often shown to reduce the hours dedicated towards anatomy education. A medical school therefore should reevaluate its own curriculum what the students need to learn. Since anatomy is exposed to the students at the outset of a curriculum [1], medical schools, therefore, should be careful in planning students-directed anatomy objectives and how they are going to be delivered. This is important as the current pressure to reduce the hours devoted to learning anatomy may even complicate the entire planning [2,3].","PeriodicalId":8778,"journal":{"name":"Biochemistry international","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83085784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-02-15DOI: 10.19080/APBIJ.2017.01.555565
R. Singh
Of late there has been a great buzz about the abnormal rise in the caesarean rate in most of the countries, raising a concern. In some this is more apparent under the private health care facilities. In fact this upward trend has been observed since the beginning of this century. As per recent data over 30 % women are experiencing a caesarean delivery (CD). In 2014, in the United States, 32.2% of pregnant women delivered through this bypass, accounting for over one million surgeries [1]. This upward trend to rely on the surgical delivery during the closing years of the last century did not convert into better outcomes
{"title":"Approach to Lower the Caesarean Delivery Rate - Preventing the First Caesarean","authors":"R. Singh","doi":"10.19080/APBIJ.2017.01.555565","DOIUrl":"https://doi.org/10.19080/APBIJ.2017.01.555565","url":null,"abstract":"Of late there has been a great buzz about the abnormal rise in the caesarean rate in most of the countries, raising a concern. In some this is more apparent under the private health care facilities. In fact this upward trend has been observed since the beginning of this century. As per recent data over 30 % women are experiencing a caesarean delivery (CD). In 2014, in the United States, 32.2% of pregnant women delivered through this bypass, accounting for over one million surgeries [1]. This upward trend to rely on the surgical delivery during the closing years of the last century did not convert into better outcomes","PeriodicalId":8778,"journal":{"name":"Biochemistry international","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90686115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-12-19DOI: 10.19080/APBIJ.2016.01.555562
D. Brunelli
{"title":"The Children of War one Perverse Inclusion-One Vision","authors":"D. Brunelli","doi":"10.19080/APBIJ.2016.01.555562","DOIUrl":"https://doi.org/10.19080/APBIJ.2016.01.555562","url":null,"abstract":"","PeriodicalId":8778,"journal":{"name":"Biochemistry international","volume":"114 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86255181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-12-19DOI: 10.19080/APBIJ.2016.01.555563
H. Balcioglu
Teeth, impacted at unusual positions far from their normal anatomical location, are called ectopic teeth [1]. An extra tooth with an abnormal morphology is usually called as supernumerary tooth, whereas it is called as supplementary tooth if the morphology is normal [2,3]. The reported prevalence of supernumerary teeth varies between %0,45 and %3 and they might erupt ectopically. There is female predominance with a ratio of 2:1 [2]. Ectopic teeth may erupt in various sites such as mandibular condyle and coronoid processes, maxillary sinus, orbital floor, palate, facial skin, nasal cavity, inferior nasal concha and oropharynx. Most supernumerary teeth are located in the anterior maxillary region and ectopic eruption of teeth in maxillary sinus is rare [3-6]. The present paper reports one inverted supernumerary and one inverted supplemental ectopic tooth located in maxillary sinuses.
{"title":"Two Cases of Inverted Ectopic Teeth in Maxillary Sinus","authors":"H. Balcioglu","doi":"10.19080/APBIJ.2016.01.555563","DOIUrl":"https://doi.org/10.19080/APBIJ.2016.01.555563","url":null,"abstract":"Teeth, impacted at unusual positions far from their normal anatomical location, are called ectopic teeth [1]. An extra tooth with an abnormal morphology is usually called as supernumerary tooth, whereas it is called as supplementary tooth if the morphology is normal [2,3]. The reported prevalence of supernumerary teeth varies between %0,45 and %3 and they might erupt ectopically. There is female predominance with a ratio of 2:1 [2]. Ectopic teeth may erupt in various sites such as mandibular condyle and coronoid processes, maxillary sinus, orbital floor, palate, facial skin, nasal cavity, inferior nasal concha and oropharynx. Most supernumerary teeth are located in the anterior maxillary region and ectopic eruption of teeth in maxillary sinus is rare [3-6]. The present paper reports one inverted supernumerary and one inverted supplemental ectopic tooth located in maxillary sinuses.","PeriodicalId":8778,"journal":{"name":"Biochemistry international","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90012641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-12-08DOI: 10.19080/APBIJ.2016.01.555561
A. Cantani
Allergic asthma and rhinitis, atopic dermatitis (AD), urticaria and gastrointestinal allergy, are common diseases of infants and children. It was recently estimated that 14% of children suffer from AD, 8% from food allergy, and 12% from asthma [1,2]. The cumulated incidence of these diseases in adolescents has been estimated between 25-35%, while the prevalence is about 20% [3]. The phenotypic expression of these illnesses varies extensively, being very mild in some cases, severe in many, and even life threatening in others. Specific IgE antibodies to foods and positive challenge tests to a number of food allergens are frequently present in children with these disorders. Cow’s milk (CM) appears to be the most
{"title":"The Environmental Factors Influencing the Development of Atopic Diseases Discussed In 2532 Children","authors":"A. Cantani","doi":"10.19080/APBIJ.2016.01.555561","DOIUrl":"https://doi.org/10.19080/APBIJ.2016.01.555561","url":null,"abstract":"Allergic asthma and rhinitis, atopic dermatitis (AD), urticaria and gastrointestinal allergy, are common diseases of infants and children. It was recently estimated that 14% of children suffer from AD, 8% from food allergy, and 12% from asthma [1,2]. The cumulated incidence of these diseases in adolescents has been estimated between 25-35%, while the prevalence is about 20% [3]. The phenotypic expression of these illnesses varies extensively, being very mild in some cases, severe in many, and even life threatening in others. Specific IgE antibodies to foods and positive challenge tests to a number of food allergens are frequently present in children with these disorders. Cow’s milk (CM) appears to be the most","PeriodicalId":8778,"journal":{"name":"Biochemistry international","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91115111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-12-07DOI: 10.19080/APBIJ.2016.01.555560
A. Cantani
Allergy and Clinical Immunology Division, Department of Pediatrics, University of Roma “La Sapienza” Medical School Breastfeeding Normal neonates are equipped with a limited immune competence, therefore they need breast milk (BM), which represent an excellent immune protection for the neonate during the critical period of intestinal vulnerability, due to a great variety of functionally interactive immunological, antibacterial, antiviral, anti inflammatory and immune modulating factors. Evidence suggests that the protection afforded by human milk to the recipient infant is greatest when breast-feeding is exclusive and of substantial duration. In this update of an old topic, we shall review it’s maim role in atopy prevention as an introduction to the immunological and non immunological components of BM and colostrum, and the spectrum and mechanisms of the protection of host defenses.
罗马大学" La Sapienza "医学院儿科学系过敏和临床免疫学科母乳喂养正常新生儿的免疫能力有限，因此他们需要母乳(BM)，由于多种功能相互作用的免疫、抗菌、抗病毒、抗炎和免疫调节因子，母乳在肠道脆弱的关键时期为新生儿提供了极好的免疫保护。有证据表明，母乳对接受母乳的婴儿提供的保护在纯母乳喂养和长时间母乳喂养的情况下是最大的。本文将从牛初乳和牛初乳的免疫和非免疫成分、宿主防御保护的谱和机制等方面综述牛初乳在预防特应性反应中的主要作用。
{"title":"Food Allergy and Breastfeeding","authors":"A. Cantani","doi":"10.19080/APBIJ.2016.01.555560","DOIUrl":"https://doi.org/10.19080/APBIJ.2016.01.555560","url":null,"abstract":"Allergy and Clinical Immunology Division, Department of Pediatrics, University of Roma “La Sapienza” Medical School Breastfeeding Normal neonates are equipped with a limited immune competence, therefore they need breast milk (BM), which represent an excellent immune protection for the neonate during the critical period of intestinal vulnerability, due to a great variety of functionally interactive immunological, antibacterial, antiviral, anti inflammatory and immune modulating factors. Evidence suggests that the protection afforded by human milk to the recipient infant is greatest when breast-feeding is exclusive and of substantial duration. In this update of an old topic, we shall review it’s maim role in atopy prevention as an introduction to the immunological and non immunological components of BM and colostrum, and the spectrum and mechanisms of the protection of host defenses.","PeriodicalId":8778,"journal":{"name":"Biochemistry international","volume":"118 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79974694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-10-12DOI: 10.19080/APBIJ.2016.01.555558
B. Sharma
Acetylcholinesterase (AChE) (EC 3.1.1.7) is the primary cholinesterase belongs to carboxylesterase family . It is an acetylhydrolase, found in many types of conducting tissues. AChE is also found on the red blood cell membranes and blood plasma (EC 3.1.1.8, ChE) [1]. The function of AChE is the termination of ACh at the junctions of the various cholinergic nerve endings with their post-synaptic sites which catalyzes the breakdown of acetylcholine that function as neurotransmitters with very high catalytic activity. The turn over number for AChE has been found to be about 25000 molecules of acetylcholine (ACh) hydrolysed per second [2]. The AChE activity is higher in motor neurons than in sensory neurons [3,4]. AChE exists in multiple molecular forms with different oligomeric assembly but having the same catalytic activities. The enzyme has been reported to be membrane bound [5-7]. The active site of AChE has two sub sites anionic site and esteraticsubsite. The esteraticsubsite contains the catalytic triad of three amino acids: serine 200, histidine 440 and glutamate 327 similar to the triad in other serine proteases except that the glutamate is the third member rather than aspartate, where acetylcholine is hydrolyzed to acetate and choline [8]. The hydrolysis reaction of the carboxyl ester forms an acyl-enzyme and free choline. Then, the acyl-enzyme undergoes nucleophilic attack by a water molecule, assisted by the histidine 440 group, liberating acetic acid and regenerating the free enzyme [9,10]. The mechanism of action of AChE has been elucidated in (Figure 1). The anionic sub site accommodates the positive quaternary amine of acetylcholine and other cationic substrates and inhibitors. The cationic substrates are not bound by interaction of 14 aromatic amino residues [11], which are highly conserved across different species [12]. Among these aromatic amino acids the substitution of tryptophan 84 with alanineresults in a 3000-fold decreased reactivity [13]. During neurotransmission, ACh is released
{"title":"Alleviation of Acute Poisoning of Organophosphates in Humans","authors":"B. Sharma","doi":"10.19080/APBIJ.2016.01.555558","DOIUrl":"https://doi.org/10.19080/APBIJ.2016.01.555558","url":null,"abstract":"Acetylcholinesterase (AChE) (EC 3.1.1.7) is the primary cholinesterase belongs to carboxylesterase family . It is an acetylhydrolase, found in many types of conducting tissues. AChE is also found on the red blood cell membranes and blood plasma (EC 3.1.1.8, ChE) [1]. The function of AChE is the termination of ACh at the junctions of the various cholinergic nerve endings with their post-synaptic sites which catalyzes the breakdown of acetylcholine that function as neurotransmitters with very high catalytic activity. The turn over number for AChE has been found to be about 25000 molecules of acetylcholine (ACh) hydrolysed per second [2]. The AChE activity is higher in motor neurons than in sensory neurons [3,4]. AChE exists in multiple molecular forms with different oligomeric assembly but having the same catalytic activities. The enzyme has been reported to be membrane bound [5-7]. The active site of AChE has two sub sites anionic site and esteraticsubsite. The esteraticsubsite contains the catalytic triad of three amino acids: serine 200, histidine 440 and glutamate 327 similar to the triad in other serine proteases except that the glutamate is the third member rather than aspartate, where acetylcholine is hydrolyzed to acetate and choline [8]. The hydrolysis reaction of the carboxyl ester forms an acyl-enzyme and free choline. Then, the acyl-enzyme undergoes nucleophilic attack by a water molecule, assisted by the histidine 440 group, liberating acetic acid and regenerating the free enzyme [9,10]. The mechanism of action of AChE has been elucidated in (Figure 1). The anionic sub site accommodates the positive quaternary amine of acetylcholine and other cationic substrates and inhibitors. The cationic substrates are not bound by interaction of 14 aromatic amino residues [11], which are highly conserved across different species [12]. Among these aromatic amino acids the substitution of tryptophan 84 with alanineresults in a 3000-fold decreased reactivity [13]. During neurotransmission, ACh is released","PeriodicalId":8778,"journal":{"name":"Biochemistry international","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79028502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-09-16DOI: 10.19080/APBIJ.2016.01.555557
E. Molina
Marta Martinez Wheeler and Justo Luis Pereda address the use of methods problémicos Philosophy, Jorge Luis Hernandez Mujica and Ines Salcedo in Biology , Bernardino A. Almeida and José Tomás in mathematics , Felicia Gates and Barbara Fierro in literature , Margarita Gonzalez and Yamile Quintero in history, Juan Túrcaz and Maria del Carmen Puñales foreign language , Maria del Carmen Leon and Pablo Hernandez in the teaching of chemistry , however , have not been reported similar studies in the Anatomy discipline and Human Physiology accessed in Los problémicos teaching methods Ignacio Ramirez [1].
玛尔塔·马丁内斯·维勒和胡斯托·路易斯·佩雷达在哲学上使用了问题的方法，生物学上使用了Jorge Luis Hernandez Mujica和Ines Salcedo，数学上使用了Bernardino A. Almeida和jos Tomás，文学上使用了Felicia Gates和Barbara Fierro，历史上使用了Margarita Gonzalez和Yamile Quintero, Juan Túrcaz和Maria del Carmen Puñales使用了外语，化学教学中使用了Maria del Carmen Leon和Pablo Hernandez，在Los problem - samicos的教学方法Ignacio Ramirez[1]中，解剖学科和人体生理学没有类似的研究报道。
{"title":"The Problamatic Methods in Teaching of Human Anatomy and Physiology","authors":"E. Molina","doi":"10.19080/APBIJ.2016.01.555557","DOIUrl":"https://doi.org/10.19080/APBIJ.2016.01.555557","url":null,"abstract":"Marta Martinez Wheeler and Justo Luis Pereda address the use of methods problémicos Philosophy, Jorge Luis Hernandez Mujica and Ines Salcedo in Biology , Bernardino A. Almeida and José Tomás in mathematics , Felicia Gates and Barbara Fierro in literature , Margarita Gonzalez and Yamile Quintero in history, Juan Túrcaz and Maria del Carmen Puñales foreign language , Maria del Carmen Leon and Pablo Hernandez in the teaching of chemistry , however , have not been reported similar studies in the Anatomy discipline and Human Physiology accessed in Los problémicos teaching methods Ignacio Ramirez [1].","PeriodicalId":8778,"journal":{"name":"Biochemistry international","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85216600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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