Pub Date : 2018-12-30DOI: 10.18413/2075-4728-2018-41-4-576-583
E. Isakov, A. O. Abdumomunov, A. T. Kulukeeva
The article considers the problem of studying adaptive-compensatory reactions of the body, as they provide the body adaptation to the dentition integrity break. Partial adentia is a very significant violation in the structure of the whole system because the dental arches of the upper and lower jaws provide full chewing as one of the functions of the body. In the changed condition of the functional chewing system the adaptation-compensatory mechanisms start acting to adapt to these conditions. Adaptive reactions help the biosystem to change its structures and functions while the compensatory ones provide the integral system with its main function. Dynamic processes of age-related changes in the dentition were considered using the biometric method at studying the jaw models. Results of biometric studies of the jaw diagnostic models are presented in three tables below. The method of biometric studies considering the morphofunctional periodontal reorganization dynamics provides the opportunity to select the way to eliminate the partial teeth loss at taking into account adaptive-compensatory reactions. of of of the and supporting teeth on a mathematical model].
{"title":"Biometric research of adaptive-compensatory changes in the dentoalveolar system with partial loss of teeth","authors":"E. Isakov, A. O. Abdumomunov, A. T. Kulukeeva","doi":"10.18413/2075-4728-2018-41-4-576-583","DOIUrl":"https://doi.org/10.18413/2075-4728-2018-41-4-576-583","url":null,"abstract":"The article considers the problem of studying adaptive-compensatory reactions of the body, as they provide the body adaptation to the dentition integrity break. Partial adentia is a very significant violation in the structure of the whole system because the dental arches of the upper and lower jaws provide full chewing as one of the functions of the body. In the changed condition of the functional chewing system the adaptation-compensatory mechanisms start acting to adapt to these conditions. Adaptive reactions help the biosystem to change its structures and functions while the compensatory ones provide the integral system with its main function. Dynamic processes of age-related changes in the dentition were considered using the biometric method at studying the jaw models. Results of biometric studies of the jaw diagnostic models are presented in three tables below. The method of biometric studies considering the morphofunctional periodontal reorganization dynamics provides the opportunity to select the way to eliminate the partial teeth loss at taking into account adaptive-compensatory reactions. of of of the and supporting teeth on a mathematical model].","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80893555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-30DOI: 10.18413/2075-4728-2018-41-4-528-538
И.В. Аскари, I. V. Askari, Хсн, небиволол, оксид азота
The use of P-adrenergic blockers (P-blockers) in heart failure has been considered controversial for many years. However, they are recommended as a first-line treatment for chronic heart failure, coronary heart disease, atrial fibrillation, and in patients with recent acute myocardial infarction. Randomized clinical trials and meta-analyses have shown that long-term use of P-blockers improves the outcome of patients with coronary heart failure, leading to a significant reduction in the risk of cardiovascular events, mortality and sudden death. The choice of therapy in patients with cardiovascular disease must consider the presence of risk factors and concomitant conditions, as well as the individual characteristics of the drugs in question. Nebivolol induces mediated vasodilation by stimulating endothelial nitric oxide synthase through P3-agonism. This mechanism of action accentuate several hemodynamic qualities of nebivolol, which include reduced heart rate, blood pressure, improved systolic and diastolic heart function. The literature review presents data on the use of P-blockers in relation to cardiovascular diseases, the pharmacological profile of nebivolol, as well as clinical data confirming its positive effect on the course of chronic heart failure. Ключевые слова: бета-адреноблокаторы (Р-блокаторы), хроническая небиволол, оксид азота (NO). approaches to the interpretation of the results of clinical studies of beta-blockers in the treatment of patients with chronic heart failure] Ratsional'naya
{"title":"Features of pharmacotherapy β1- adrenoblocker with activation of endothelial nitric oxide nebivolol in patients with coronary heart disease on the background of chronic heart failure (review of literature)","authors":"И.В. Аскари, I. V. Askari, Хсн, небиволол, оксид азота","doi":"10.18413/2075-4728-2018-41-4-528-538","DOIUrl":"https://doi.org/10.18413/2075-4728-2018-41-4-528-538","url":null,"abstract":"The use of P-adrenergic blockers (P-blockers) in heart failure has been considered controversial for many years. However, they are recommended as a first-line treatment for chronic heart failure, coronary heart disease, atrial fibrillation, and in patients with recent acute myocardial infarction. Randomized clinical trials and meta-analyses have shown that long-term use of P-blockers improves the outcome of patients with coronary heart failure, leading to a significant reduction in the risk of cardiovascular events, mortality and sudden death. The choice of therapy in patients with cardiovascular disease must consider the presence of risk factors and concomitant conditions, as well as the individual characteristics of the drugs in question. Nebivolol induces mediated vasodilation by stimulating endothelial nitric oxide synthase through P3-agonism. This mechanism of action accentuate several hemodynamic qualities of nebivolol, which include reduced heart rate, blood pressure, improved systolic and diastolic heart function. The literature review presents data on the use of P-blockers in relation to cardiovascular diseases, the pharmacological profile of nebivolol, as well as clinical data confirming its positive effect on the course of chronic heart failure. Ключевые слова: бета-адреноблокаторы (Р-блокаторы), хроническая небиволол, оксид азота (NO). approaches to the interpretation of the results of clinical studies of beta-blockers in the treatment of patients with chronic heart failure] Ratsional'naya","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90869428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-30DOI: 10.18413/2075-4728-2018-41-4-652-658
L. G. Dvornikova, N. G. Bekisheva, O. N. Mazko, Y. Korenovsky
{"title":"Development of technology of liposomal forms of corn silk dry extract","authors":"L. G. Dvornikova, N. G. Bekisheva, O. N. Mazko, Y. Korenovsky","doi":"10.18413/2075-4728-2018-41-4-652-658","DOIUrl":"https://doi.org/10.18413/2075-4728-2018-41-4-652-658","url":null,"abstract":"","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77738489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-30DOI: 10.18413/2075-4728-2018-41-4-625-632
A. V. Gordiets, М.Y. Galaktionova, D. Maiseenko
The article describes the experience of the volunteer work of medical university students with teen girls in schools in the prevention of reproductive health problems. The article describes an example of the organization of a health lesson «I am a girl and a future mother!» by the students under the guidance of teachers, pediatricians and obstetricians. For the first time in
{"title":"Prevention of reproductive health problems among аdolescent girls","authors":"A. V. Gordiets, М.Y. Galaktionova, D. Maiseenko","doi":"10.18413/2075-4728-2018-41-4-625-632","DOIUrl":"https://doi.org/10.18413/2075-4728-2018-41-4-625-632","url":null,"abstract":"The article describes the experience of the volunteer work of medical university students with teen girls in schools in the prevention of reproductive health problems. The article describes an example of the organization of a health lesson «I am a girl and a future mother!» by the students under the guidance of teachers, pediatricians and obstetricians. For the first time in","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84428969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-30DOI: 10.18413/2075-4728-2018-41-4-547-557
M. M. Kiselevich, О.А. Efremova, G. Petrova
The article is devoted to the study of acute coronary syndrome. The analysis was conducted 1206 of case histories from middle-aged, elderly and senile patients with acute coronary syndrome. Evaluated by clinical symptoms and risk factors of acute coronary syndrome, laboratory tests, electrocardiography (ECG) in 12 leads and echocardiography. That was dominated by men (61.8 %), middle and old age (35.8 % and 39.0 % respectively). On the outcome of the confirmed the diagnosis of unstable angina or heart attack the myocardium. The effectiveness of the treatment amounted to 92.0 %.Tthe results showed that patients with non-ST segment elevations (NSTEMI), which were later discharged from hospital; it was 4 times more than with ST segment elevation (STEMI). Deceased patients group STEMI and NSTEMI nobody. However, it was noted that most of the dead with NSTEMI accounted for patients with unstable angina. However, it was noted that most of the dead comprised patients with unstable angina. They all had a high degree of risk (male sex, advanced age, background and comorbidic diseases), the outcome also influenced the time from the beginning of symptoms before entering hospital and treatment tactics.
{"title":"Clinical current and outcomes of the acute coronary syndrome","authors":"M. M. Kiselevich, О.А. Efremova, G. Petrova","doi":"10.18413/2075-4728-2018-41-4-547-557","DOIUrl":"https://doi.org/10.18413/2075-4728-2018-41-4-547-557","url":null,"abstract":"The article is devoted to the study of acute coronary syndrome. The analysis was conducted 1206 of case histories from middle-aged, elderly and senile patients with acute coronary syndrome. Evaluated by clinical symptoms and risk factors of acute coronary syndrome, laboratory tests, electrocardiography (ECG) in 12 leads and echocardiography. That was dominated by men (61.8 %), middle and old age (35.8 % and 39.0 % respectively). On the outcome of the confirmed the diagnosis of unstable angina or heart attack the myocardium. The effectiveness of the treatment amounted to 92.0 %.Tthe results showed that patients with non-ST segment elevations (NSTEMI), which were later discharged from hospital; it was 4 times more than with ST segment elevation (STEMI). Deceased patients group STEMI and NSTEMI nobody. However, it was noted that most of the dead with NSTEMI accounted for patients with unstable angina. However, it was noted that most of the dead comprised patients with unstable angina. They all had a high degree of risk (male sex, advanced age, background and comorbidic diseases), the outcome also influenced the time from the beginning of symptoms before entering hospital and treatment tactics.","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75357688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-30DOI: 10.18413/2075-4728-2018-41-4-519-527
L. V. Shekhovtsova, O. Osipova, A. Golovin, K. G. Plaksina, A. A. Dolzhikov
{"title":"Influence of methods of pharmacotherapy in myocardial remodeling of the left ventricle in patients with acute myocardial infarction after reperfusion in the prevention of the formation of CHF (review of literature)","authors":"L. V. Shekhovtsova, O. Osipova, A. Golovin, K. G. Plaksina, A. A. Dolzhikov","doi":"10.18413/2075-4728-2018-41-4-519-527","DOIUrl":"https://doi.org/10.18413/2075-4728-2018-41-4-519-527","url":null,"abstract":"","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88845640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-09-30DOI: 10.18413/2075-4728-2018-41-3-473-483
N. Lyapunov, I. Zinchenko, E. Bezuglaya
{"title":"Identification and assay of the ketoprofen esters","authors":"N. Lyapunov, I. Zinchenko, E. Bezuglaya","doi":"10.18413/2075-4728-2018-41-3-473-483","DOIUrl":"https://doi.org/10.18413/2075-4728-2018-41-3-473-483","url":null,"abstract":"","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82326893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-09-30DOI: 10.18413/2075-4728-2018-41-3-449-456
A. G. Lastovetsky, V. I. Timoshilov
{"title":"The evaluation of educational requests for the training of drug abuse prevention volunteers","authors":"A. G. Lastovetsky, V. I. Timoshilov","doi":"10.18413/2075-4728-2018-41-3-449-456","DOIUrl":"https://doi.org/10.18413/2075-4728-2018-41-3-449-456","url":null,"abstract":"","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77164177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-09-30DOI: 10.18413/2075-4728-2018-41-3-464-472
A. V. Nalyotov, A. Barinova, O. Gorshkov
{"title":"The evaluation of the effectiveness of treatment of ulcer disease in children depending on the level of parental compliance","authors":"A. V. Nalyotov, A. Barinova, O. Gorshkov","doi":"10.18413/2075-4728-2018-41-3-464-472","DOIUrl":"https://doi.org/10.18413/2075-4728-2018-41-3-464-472","url":null,"abstract":"","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73694923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-09-30DOI: 10.18413/2075-4728-2018-41-3-495-501
K. V. Andryukov, L. M. Korkodinova
{"title":"Investigation of the «Structure-antimicrobial acvity» relationship using molecular docking in the series of substituted amides and hydrazides of n-aroyl-5-bromo (5-chloro) anthranilic acids","authors":"K. V. Andryukov, L. M. Korkodinova","doi":"10.18413/2075-4728-2018-41-3-495-501","DOIUrl":"https://doi.org/10.18413/2075-4728-2018-41-3-495-501","url":null,"abstract":"","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84856479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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