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Biometric research of adaptive-compensatory changes in the dentoalveolar system with partial loss of teeth 部分牙齿缺失后牙槽系统适应性代偿变化的生物计量学研究
Pub Date : 2018-12-30 DOI: 10.18413/2075-4728-2018-41-4-576-583
E. Isakov, A. O. Abdumomunov, A. T. Kulukeeva
The article considers the problem of studying adaptive-compensatory reactions of the body, as they provide the body adaptation to the dentition integrity break. Partial adentia is a very significant violation in the structure of the whole system because the dental arches of the upper and lower jaws provide full chewing as one of the functions of the body. In the changed condition of the functional chewing system the adaptation-compensatory mechanisms start acting to adapt to these conditions. Adaptive reactions help the biosystem to change its structures and functions while the compensatory ones provide the integral system with its main function. Dynamic processes of age-related changes in the dentition were considered using the biometric method at studying the jaw models. Results of biometric studies of the jaw diagnostic models are presented in three tables below. The method of biometric studies considering the morphofunctional periodontal reorganization dynamics provides the opportunity to select the way to eliminate the partial teeth loss at taking into account adaptive-compensatory reactions. of of of the and supporting teeth on a mathematical model].
本文考虑了研究机体对牙列完整性断裂的适应性补偿反应的问题。部分牙齿缺失是对整个系统结构的严重破坏因为上颚和下颚的牙弓作为身体的功能之一提供了充分的咀嚼。在功能性咀嚼系统改变的条件下,适应补偿机制开始发挥作用以适应这些条件。适应性反应帮助生物系统改变其结构和功能,而代偿性反应则为整体系统提供其主要功能。在研究颌骨模型时,考虑了牙列年龄相关变化的动态过程。颌骨诊断模型的生物计量学研究结果如下表所示。生物计量学研究的方法考虑形态功能牙周重组动力学提供了机会,选择的方式来消除部分牙齿的损失,同时考虑到适应性补偿反应。[数学模型上的]牙齿的或支撑牙齿的]
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引用次数: 0
Features of pharmacotherapy β1- adrenoblocker with activation of endothelial nitric oxide nebivolol in patients with coronary heart disease on the background of chronic heart failure (review of literature) 慢性心力衰竭背景下β1-肾上腺素阻滞剂联合内皮细胞一氧化氮活化对冠心病患者的药物治疗特点(文献复习)
Pub Date : 2018-12-30 DOI: 10.18413/2075-4728-2018-41-4-528-538
И.В. Аскари, I. V. Askari, Хсн, небиволол, оксид азота
The use of P-adrenergic blockers (P-blockers) in heart failure has been considered controversial for many years. However, they are recommended as a first-line treatment for chronic heart failure, coronary heart disease, atrial fibrillation, and in patients with recent acute myocardial infarction. Randomized clinical trials and meta-analyses have shown that long-term use of P-blockers improves the outcome of patients with coronary heart failure, leading to a significant reduction in the risk of cardiovascular events, mortality and sudden death. The choice of therapy in patients with cardiovascular disease must consider the presence of risk factors and concomitant conditions, as well as the individual characteristics of the drugs in question. Nebivolol induces mediated vasodilation by stimulating endothelial nitric oxide synthase through P3-agonism. This mechanism of action accentuate several hemodynamic qualities of nebivolol, which include reduced heart rate, blood pressure, improved systolic and diastolic heart function. The literature review presents data on the use of P-blockers in relation to cardiovascular diseases, the pharmacological profile of nebivolol, as well as clinical data confirming its positive effect on the course of chronic heart failure. Ключевые слова: бета-адреноблокаторы (Р-блокаторы), хроническая небиволол, оксид азота (NO). approaches to the interpretation of the results of clinical studies of beta-blockers in the treatment of patients with chronic heart failure] Ratsional'naya
在心力衰竭中使用p -肾上腺素能阻滞剂(P-blockers)多年来一直被认为是有争议的。然而,它们被推荐作为慢性心力衰竭、冠心病、心房颤动和近期急性心肌梗死患者的一线治疗。随机临床试验和荟萃分析表明,长期使用p受体阻滞剂可以改善冠心病患者的预后,显著降低心血管事件、死亡率和猝死的风险。心血管疾病患者的治疗选择必须考虑危险因素和伴随条件的存在,以及所涉药物的个体特征。奈比洛尔通过p3激动作用刺激内皮一氧化氮合酶,诱导介导的血管舒张。这种作用机制强化了奈比洛尔的几个血液动力学特性,包括降低心率、血压、改善心脏收缩和舒张功能。文献综述介绍了与心血管疾病相关的p受体阻滞剂的使用数据,奈比洛尔的药理学概况,以及证实其对慢性心力衰竭病程的积极作用的临床数据。Ключевыеслова:бета-адреноблокаторы(Рблокаторы),хроническаянебиволол,оксидазота(不)。-受体阻滞剂治疗慢性心力衰竭患者的临床研究结果的解释方法[Ratsional'naya]
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引用次数: 0
Development of technology of liposomal forms of corn silk dry extract 玉米丝干提取物脂质体制备技术的研究进展
Pub Date : 2018-12-30 DOI: 10.18413/2075-4728-2018-41-4-652-658
L. G. Dvornikova, N. G. Bekisheva, O. N. Mazko, Y. Korenovsky
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引用次数: 0
Prevention of reproductive health problems among аdolescent girls 预防少女的生殖健康问题
Pub Date : 2018-12-30 DOI: 10.18413/2075-4728-2018-41-4-625-632
A. V. Gordiets, М.Y. Galaktionova, D. Maiseenko
The article describes the experience of the volunteer work of medical university students with teen girls in schools in the prevention of reproductive health problems. The article describes an example of the organization of a health lesson «I am a girl and a future mother!» by the students under the guidance of teachers, pediatricians and obstetricians. For the first time in
本文介绍了医科大学女青少年在校志愿工作在预防生殖健康问题方面的体会。文章描述了一个组织健康课的例子“我是一个女孩和一个未来的母亲!”由学生在老师、儿科医生和产科医生的指导下进行。有生以来第一次
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引用次数: 0
Clinical current and outcomes of the acute coronary syndrome 急性冠状动脉综合征的临床现状及预后
Pub Date : 2018-12-30 DOI: 10.18413/2075-4728-2018-41-4-547-557
M. M. Kiselevich, О.А. Efremova, G. Petrova
The article is devoted to the study of acute coronary syndrome. The analysis was conducted 1206 of case histories from middle-aged, elderly and senile patients with acute coronary syndrome. Evaluated by clinical symptoms and risk factors of acute coronary syndrome, laboratory tests, electrocardiography (ECG) in 12 leads and echocardiography. That was dominated by men (61.8 %), middle and old age (35.8 % and 39.0 % respectively). On the outcome of the confirmed the diagnosis of unstable angina or heart attack the myocardium. The effectiveness of the treatment amounted to 92.0 %.Tthe results showed that patients with non-ST segment elevations (NSTEMI), which were later discharged from hospital; it was 4 times more than with ST segment elevation (STEMI). Deceased patients group STEMI and NSTEMI nobody. However, it was noted that most of the dead with NSTEMI accounted for patients with unstable angina. However, it was noted that most of the dead comprised patients with unstable angina. They all had a high degree of risk (male sex, advanced age, background and comorbidic diseases), the outcome also influenced the time from the beginning of symptoms before entering hospital and treatment tactics.
这篇文章致力于急性冠状动脉综合征的研究。对1206例中、老年、老年急性冠状动脉综合征患者的病史进行分析。通过急性冠脉综合征的临床症状和危险因素、实验室检查、12导联心电图和超声心动图进行评价。以男性(61.8%)、中年和老年(分别为35.8%和39.0%)为主。对不稳定型心绞痛或心肌梗塞的诊断结果进行分析。治疗有效率达92.0%。结果显示,非st段抬高(NSTEMI)患者,随后出院;ST段抬高组(STEMI)的4倍以上。死者组STEMI和非STEMI没有。然而,值得注意的是,大多数NSTEMI死亡患者为不稳定型心绞痛患者。然而,值得注意的是,大多数死者是不稳定型心绞痛患者。他们都有很高的风险(男性、高龄、背景和合并症),结果也影响到从症状开始到进入医院的时间和治疗策略。
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引用次数: 0
Influence of methods of pharmacotherapy in myocardial remodeling of the left ventricle in patients with acute myocardial infarction after reperfusion in the prevention of the formation of CHF (review of literature) 急性心肌梗死再灌注后左室心肌重构药物治疗方法对预防CHF形成的影响(文献复习)
Pub Date : 2018-12-30 DOI: 10.18413/2075-4728-2018-41-4-519-527
L. V. Shekhovtsova, O. Osipova, A. Golovin, K. G. Plaksina, A. A. Dolzhikov
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引用次数: 1
Identification and assay of the ketoprofen esters 酮洛芬酯的鉴定与测定
Pub Date : 2018-09-30 DOI: 10.18413/2075-4728-2018-41-3-473-483
N. Lyapunov, I. Zinchenko, E. Bezuglaya
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引用次数: 2
The evaluation of educational requests for the training of drug abuse prevention volunteers 对预防药物滥用志愿人员培训的教育要求进行评价
Pub Date : 2018-09-30 DOI: 10.18413/2075-4728-2018-41-3-449-456
A. G. Lastovetsky, V. I. Timoshilov
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引用次数: 0
The evaluation of the effectiveness of treatment of ulcer disease in children depending on the level of parental compliance 评估儿童溃疡疾病治疗的有效性取决于父母的依从性
Pub Date : 2018-09-30 DOI: 10.18413/2075-4728-2018-41-3-464-472
A. V. Nalyotov, A. Barinova, O. Gorshkov
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引用次数: 0
Investigation of the «Structure-antimicrobial acvity» relationship using molecular docking in the series of substituted amides and hydrazides of n-aroyl-5-bromo (5-chloro) anthranilic acids 用分子对接法研究n-芳基-5-溴(5-氯)邻氨基苯甲酸取代酰胺和酰肼的“结构-抗菌活性”关系
Pub Date : 2018-09-30 DOI: 10.18413/2075-4728-2018-41-3-495-501
K. V. Andryukov, L. M. Korkodinova
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引用次数: 0
期刊
Belgorod State University Scientific bulletin Medicine Pharmacy
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