首页 > 最新文献

Belgorod State University Scientific bulletin Medicine Pharmacy最新文献

英文 中文
Approbation of the method of enzymatic hydrolysis on natural and dyed hair for the extraction of medicinal substances 天然和染色头发酶解法提取药用物质的研究
Pub Date : 2018-12-30 DOI: 10.18413/2075-4728-2018-41-4-659-671
M. V. Krys'ko, Saint-Petersburg State Chemical, Yu. V. Slustovskaya, O. Strelova, V. Kuklin
The objective of the present study was to test the developed methods of enzymatic hydrolysis on natural and dyed fur (hair) and analyze the effect of bleaching on the results of a chemical toxicological analysis. The experiments were carried out with the used laboratory animals (red hair and black hair female guinea pigs) that had been daily given a diphenhydramine solution per os during 6 months preceding the study. It was shown that natural black and red hair (fur) have a similar composition of endogenous substances. Bleaching is a process of gaining much lighter hair color than natural one. And along with this, there is a destruction of natural hair pigment. The effect of the bleaching does not affect the background level of endogenous substances and does not interfere with the further determination of the model drug substance. Methods of enzymatic hydrolysis can be used to isolate substances from both natural colored and dyed hair (fur). The degree of extraction of diphenhydramine, a model drug substance, from bleached fur was 1.5-2 times higher than the degree of extraction of it from natural colored, which should be take into consideration when interpreting the results. This study can be used to diagnose the use of narcotic drugs and psychotropic substances. It is planned to conduct further studies on sectional analysis of hair. of synthetic psychoactive substances and their metabolites in and nails by liquid chromatography methods with mass spec-trometric detection] Informacionnoe Стрелова О.Ю., Сивакова М.А. 2017. Применение методики
本研究的目的是测试已开发的酶解方法对天然和染色毛(毛),并分析漂白对化学毒理学分析结果的影响。实验用实验动物(红毛和黑毛雌性豚鼠)进行,在研究前6个月每天给予苯海拉明溶液。结果表明,天然黑毛和红毛的内源性物质组成相似。漂白是一种获得比自然发色浅得多的发色的过程。与此同时,天然的头发色素也会被破坏。漂白的效果不影响内源性物质的本底水平,也不干扰模型药物物质的进一步测定。酶解方法可用于从天然染色和染色的头发(皮毛)中分离物质。从脱色毛皮中提取模型药物苯海拉明的程度比从天然染色毛皮中提取苯海拉明的程度高1.5-2倍,在解释结果时应考虑到这一点。本研究可用于麻醉药品和精神药物使用的诊断。计划对头发的截面分析进行进一步的研究。质谱联用液相色谱法测定指甲中合成精神活性物质及其代谢物[j] . Informacionnoe Стрелова О.Ю。, Сивакова М.А。2017. Применениеметодики
{"title":"Approbation of the method of enzymatic hydrolysis on natural and dyed hair for the extraction of medicinal substances","authors":"M. V. Krys'ko, Saint-Petersburg State Chemical, Yu. V. Slustovskaya, O. Strelova, V. Kuklin","doi":"10.18413/2075-4728-2018-41-4-659-671","DOIUrl":"https://doi.org/10.18413/2075-4728-2018-41-4-659-671","url":null,"abstract":"The objective of the present study was to test the developed methods of enzymatic hydrolysis on natural and dyed fur (hair) and analyze the effect of bleaching on the results of a chemical toxicological analysis. The experiments were carried out with the used laboratory animals (red hair and black hair female guinea pigs) that had been daily given a diphenhydramine solution per os during 6 months preceding the study. It was shown that natural black and red hair (fur) have a similar composition of endogenous substances. Bleaching is a process of gaining much lighter hair color than natural one. And along with this, there is a destruction of natural hair pigment. The effect of the bleaching does not affect the background level of endogenous substances and does not interfere with the further determination of the model drug substance. Methods of enzymatic hydrolysis can be used to isolate substances from both natural colored and dyed hair (fur). The degree of extraction of diphenhydramine, a model drug substance, from bleached fur was 1.5-2 times higher than the degree of extraction of it from natural colored, which should be take into consideration when interpreting the results. This study can be used to diagnose the use of narcotic drugs and psychotropic substances. It is planned to conduct further studies on sectional analysis of hair. of synthetic psychoactive substances and their metabolites in and nails by liquid chromatography methods with mass spec-trometric detection] Informacionnoe Стрелова О.Ю., Сивакова М.А. 2017. Применение методики","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73540817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Development and validation of spectrophotometric quantitative determination of terpene-indole alkaloids (for example, vincristine sulfate and vinblastine sulfate) 萜烯-吲哚类生物碱(如硫酸长春新碱和硫酸长春新碱)分光光度法定量测定方法的建立与验证
Pub Date : 2018-12-30 DOI: 10.18413/2075-4728-2018-41-4-687-702
O. V. Trineeva, A. J. Halahakun, A. I. Slivkin
{"title":"Development and validation of spectrophotometric quantitative determination of terpene-indole alkaloids (for example, vincristine sulfate and vinblastine sulfate)","authors":"O. V. Trineeva, A. J. Halahakun, A. I. Slivkin","doi":"10.18413/2075-4728-2018-41-4-687-702","DOIUrl":"https://doi.org/10.18413/2075-4728-2018-41-4-687-702","url":null,"abstract":"","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82511076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of hospital purchases of antimicrobial drugs in the framework of the pharmaceutical market the North-Western Federal District 西北联邦区医药市场框架下医院抗菌药物采购情况分析
Pub Date : 2018-12-30 DOI: 10.18413/2075-4728-2018-41-4-672-686
D. D. Siukaeva, Saint-Petersburg State Chemical, I. Narkevich, O. D. Nemyatych, I. I. Basakina
The results of the analysis of the hospital segment of the national and regional markets in the period from 2013 to 2017 are presented in the paper. It was established that volume of the Russian pharmaceutical market for hospital purchases grew by 42 % in value terms and by 8 % in physical terms over the study period. At the same time, the share of drugs represented by foreign manufacturers decreased by 5 % in value terms and by 2 % in physical terms, respectively. It has been established that in the given research conditions the group J «Antimicrobial drugs of systemic action» is the leader in the overall structure of national procurement, covering more than 30.0-35.5 % in value and more than 26.0-30.0 than 50 % of the range of antibacterial drugs. It is shown that in the structure of procurement, leading positions in terms of value were noted for foreign manufacturers, in natural units, domestic two producers play a leading role (more than 40 % of the assortment) both in the national and regional markets. At the same time, the vaccine for the prevention of pneumococcal infections (6-8 %) leads in cost terms, in natural units, ceftriaxone (about 20 %).
本文介绍了2013年至2017年期间全国和区域市场医院细分市场的分析结果。据确定,在研究期间,俄罗斯用于医院采购的药品市场的价值增长了42%,实物增长了8%。与此同时,外国制造商所占药品的份额按价值计算分别下降了5%和按实物计算分别下降了2%。已经确定,在给定的研究条件下,J组“全体性抗菌药物”在国家采购的整体结构中处于领先地位,覆盖了30.0% - 35.5%以上的价值和26.0% - 30.0%以上的抗菌药物范围。研究表明,在采购结构中,外国制造商在价值方面处于领先地位,在自然单位中,国内两家生产商在国家和地区市场上都发挥着主导作用(超过40%的分类)。与此同时,预防肺炎球菌感染的疫苗(6- 8%)以自然单位计算的成本领先于头孢曲松(约20%)。
{"title":"Analysis of hospital purchases of antimicrobial drugs in the framework of the pharmaceutical market the North-Western Federal District","authors":"D. D. Siukaeva, Saint-Petersburg State Chemical, I. Narkevich, O. D. Nemyatych, I. I. Basakina","doi":"10.18413/2075-4728-2018-41-4-672-686","DOIUrl":"https://doi.org/10.18413/2075-4728-2018-41-4-672-686","url":null,"abstract":"The results of the analysis of the hospital segment of the national and regional markets in the period from 2013 to 2017 are presented in the paper. It was established that volume of the Russian pharmaceutical market for hospital purchases grew by 42 % in value terms and by 8 % in physical terms over the study period. At the same time, the share of drugs represented by foreign manufacturers decreased by 5 % in value terms and by 2 % in physical terms, respectively. It has been established that in the given research conditions the group J «Antimicrobial drugs of systemic action» is the leader in the overall structure of national procurement, covering more than 30.0-35.5 % in value and more than 26.0-30.0 than 50 % of the range of antibacterial drugs. It is shown that in the structure of procurement, leading positions in terms of value were noted for foreign manufacturers, in natural units, domestic two producers play a leading role (more than 40 % of the assortment) both in the national and regional markets. At the same time, the vaccine for the prevention of pneumococcal infections (6-8 %) leads in cost terms, in natural units, ceftriaxone (about 20 %).","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81313446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Novosibirsk as a center of regional medical tourism: potential and implementation aspects 新西伯利亚作为区域医疗旅游中心:潜力和实施方面
Pub Date : 2018-12-30 DOI: 10.18413/2075-4728-2018-41-4-600-615
N. Goroshko, E. Emelyanova, N. Nikiforova, Biotechnology “Vector”
{"title":"Novosibirsk as a center of regional medical tourism: potential and implementation aspects","authors":"N. Goroshko, E. Emelyanova, N. Nikiforova, Biotechnology “Vector”","doi":"10.18413/2075-4728-2018-41-4-600-615","DOIUrl":"https://doi.org/10.18413/2075-4728-2018-41-4-600-615","url":null,"abstract":"","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":"146 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77767695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Analysis of the results of primary accreditation of the graduates in the field of general medicine in the center of simulation training and assessment of professional skills of Belgorod National Research Universit 别尔哥罗德国立研究型大学模拟培训和专业技能评估中心对全科医学领域毕业生的初步认证结果分析
Pub Date : 2018-12-30 DOI: 10.18413/2075-4728-2018-41-4-584-590
V. F. Kulikovsky, Y. A. Khoschenko, T. A. Nachetova, A. Nagorny
There are the results of the second round of accreditation of the graduates in the field of general medicine in Belgorod National Research University. The article explains reasons for using such indicators in assessing of professional skills quality as the average score in the accredited group for each station, percentage of persons attaining the highest grades, identification of the nature of the most frequent errors. In 2018 the graduates have higher rates of correctly implemented procedures than received in 2017 at such stations as emergency medical care ((95.79±1.70 % VS 86.63±2.95 %, Р<0.05), urgent medical care (98.34±1.08 % VS 88.77±2.76 %, Р<0.05), physical examination of cardiovascular system (97.10±1.42 % VS 90.84±2.52 %, Р<0.05). This article illustrates that raised level of skills and knowledge in 2018 is due to increasing the time available for preparations which became possible through the development of tutoring movement, students' participation in practical training competitions and the opening of The Center For Simulation Training And Assessment Of Professional Qualifications Of The Department Of Medical And Pharmaceutical Supplementary Education, Certification And Accreditation. It is stressed the need to increase the number of systematic practical skills training in simulated conditions for students of the Medical Institute. аккредитация, качество образования, практикоориентированная
这是别尔哥罗德国立研究型大学全科医学毕业生第二轮认证的结果。文章解释了在评估专业技能质量时使用这些指标的原因,如每个站点在认可组中的平均分数,获得最高分数的人的百分比,以及识别最常见错误的性质。2018年毕业生在急诊(95.79±1.70% VS 86.63±2.95%,Р<0.05)、急诊(98.34±1.08% VS 88.77±2.76%,Р<0.05)、心血管系统体检(97.10±1.42% VS 90.84±2.52%,Р<0.05)等科室的程序正确执行率均高于2017年。本文说明,2018年技能和知识水平的提高是由于增加了可用于准备的时间,这是通过发展辅导运动、学生参加实践培训比赛以及开设医学和制药补充教育、认证和认可系专业资格模拟培训和评估中心而成为可能的。强调有必要增加医学院学生在模拟条件下的系统实践技能训练的数量。аккредитация,качествообразования,практикоориентированная
{"title":"Analysis of the results of primary accreditation of the graduates in the field of general medicine in the center of simulation training and assessment of professional skills of Belgorod National Research Universit","authors":"V. F. Kulikovsky, Y. A. Khoschenko, T. A. Nachetova, A. Nagorny","doi":"10.18413/2075-4728-2018-41-4-584-590","DOIUrl":"https://doi.org/10.18413/2075-4728-2018-41-4-584-590","url":null,"abstract":"There are the results of the second round of accreditation of the graduates in the field of general medicine in Belgorod National Research University. The article explains reasons for using such indicators in assessing of professional skills quality as the average score in the accredited group for each station, percentage of persons attaining the highest grades, identification of the nature of the most frequent errors. In 2018 the graduates have higher rates of correctly implemented procedures than received in 2017 at such stations as emergency medical care ((95.79±1.70 % VS 86.63±2.95 %, Р<0.05), urgent medical care (98.34±1.08 % VS 88.77±2.76 %, Р<0.05), physical examination of cardiovascular system (97.10±1.42 % VS 90.84±2.52 %, Р<0.05). This article illustrates that raised level of skills and knowledge in 2018 is due to increasing the time available for preparations which became possible through the development of tutoring movement, students' participation in practical training competitions and the opening of The Center For Simulation Training And Assessment Of Professional Qualifications Of The Department Of Medical And Pharmaceutical Supplementary Education, Certification And Accreditation. It is stressed the need to increase the number of systematic practical skills training in simulated conditions for students of the Medical Institute. аккредитация, качество образования, практикоориентированная","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":"291 1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73165964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of thiotriazoline on the state of cellular and humoral immunity in patients with community-acquired pneumonia 硫代三唑啉对社区获得性肺炎患者细胞和体液免疫状态的影响
Pub Date : 2018-12-30 DOI: 10.18413/2075-4728-2018-41-4-558-567
V. I. Vishnevskij, I. I. Mironenko, O. Demyanenko
149 patients with community-acquired pneumonia, the influence of the antioxidant tiotriazoline on the state of cellular and humoral immunity was studied. Studies have shown that out-of-hospital pneumonia occurs against the background of secondary immunodeficiency, which is manifested by a decrease in the total circulating T-lymphocytes and their subpopulations: NK-cells, T-helper cells, T-suppressors, Ig A and Ig G increase in Ig M decrease. Tiotriazoline in the complex therapy of patients with community-acquired pneumonia is accompanied by a decrease in both total T-lymphocytopenia and their subpopulations against the background of an increase in the content of immunoglobulins of class Ig M reduction in immunoglobulin classes Ig A and Ig G. of changes in cellular and humoral immunity in patients with community-acquired against the background of course treatment with thiotriazoline
对149例社区获得性肺炎患者,观察抗氧化剂噻三唑啉对细胞免疫和体液免疫状态的影响。研究表明院外肺炎是在继发性免疫缺陷的背景下发生的,表现为循环t淋巴细胞总量及其亚群的减少:nk细胞、t辅助细胞、t抑制细胞、Ig a和Ig G增加而Ig M减少。噻三唑啉在社区获得性肺炎患者的综合治疗中伴随着总t淋巴细胞减少及其亚群的减少,其背景是Ig M类免疫球蛋白含量的增加,Ig a和Ig g类免疫球蛋白的减少。在社区获得性肺炎患者的细胞和体液免疫变化的背景下,使用噻三唑啉进行疗程治疗
{"title":"The effect of thiotriazoline on the state of cellular and humoral immunity in patients with community-acquired pneumonia","authors":"V. I. Vishnevskij, I. I. Mironenko, O. Demyanenko","doi":"10.18413/2075-4728-2018-41-4-558-567","DOIUrl":"https://doi.org/10.18413/2075-4728-2018-41-4-558-567","url":null,"abstract":"149 patients with community-acquired pneumonia, the influence of the antioxidant tiotriazoline on the state of cellular and humoral immunity was studied. Studies have shown that out-of-hospital pneumonia occurs against the background of secondary immunodeficiency, which is manifested by a decrease in the total circulating T-lymphocytes and their subpopulations: NK-cells, T-helper cells, T-suppressors, Ig A and Ig G increase in Ig M decrease. Tiotriazoline in the complex therapy of patients with community-acquired pneumonia is accompanied by a decrease in both total T-lymphocytopenia and their subpopulations against the background of an increase in the content of immunoglobulins of class Ig M reduction in immunoglobulin classes Ig A and Ig G. of changes in cellular and humoral immunity in patients with community-acquired against the background of course treatment with thiotriazoline","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":"77 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83880335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Complex evaluation of the effect of prevention of sexually transmitted infections among young people of Kursk Region 库尔斯克地区青少年预防性传播感染效果的综合评价
Pub Date : 2018-12-30 DOI: 10.18413/2075-4728-2018-41-4-640-651
A. G. Lastovetsky, V. I. Timoshilov
Sexually transmitted infections (STI) are one of the main medical and social problems of young people. The base of their prevention is formed by educational events for youth. In 2014 it was conducted a study, which shows a positive preventive effects of lectures and consults of doctors, watching of educational video, reading of special literature, self-making of informational materials and medical screening. As kinds of activities with negative effect were marked Internet-projects, social advertising, volunteer’s activities and discussions. The results of this study were presented during educational courses for doctors and teachers. The aim of the study in 2017 year was evaluating the effectiveness of the implementation of this recommendations. The program of the research included the survey of teenagers and the study of epidemiological data. The results showed the raising of the coverage of teenagers by effective preventive НАУЧНЫЕ ВЕДОМОСТИ |"Ъ Серия Медицина. Фармация. 2018. Том 41, No 4 641 activities, decreasing of incidence of STI and reducing the proportion of young people among newly diagnosed patients. Ключевые слова: половые инфекции, молодежь, профилактика, заболеваемость, оценка эффективности
性传播感染是年轻人面临的主要医疗和社会问题之一。预防这些疾病的基础是通过青少年教育活动形成的。2014年进行的一项研究表明,医生的讲座和咨询、观看教育视频、阅读专题文献、自编信息资料和医学筛查具有积极的预防效果。网络项目、社会广告、志愿者活动、讨论等活动对学生产生了负面影响。本研究的结果在医生和教师的教育课程中提出。2017年研究的目的是评估实施这些建议的有效性。研究项目包括青少年调查和流行病学资料研究。结果表明,有效的预防措施提高了青少年的覆盖率НАУЧНЫЕ ВЕДОМОСТИ |"Ъ Серия Медицина。Фармация。2018. Том 41,第4 641号活动,降低性传播感染的发病率,降低新诊断患者中年轻人的比例。Ключевыеслова:половыеинфекци,имолодежь,профилактика,заболеваемость,оценкаэффективности
{"title":"Complex evaluation of the effect of prevention of sexually transmitted infections among young people of Kursk Region","authors":"A. G. Lastovetsky, V. I. Timoshilov","doi":"10.18413/2075-4728-2018-41-4-640-651","DOIUrl":"https://doi.org/10.18413/2075-4728-2018-41-4-640-651","url":null,"abstract":"Sexually transmitted infections (STI) are one of the main medical and social problems of young people. The base of their prevention is formed by educational events for youth. In 2014 it was conducted a study, which shows a positive preventive effects of lectures and consults of doctors, watching of educational video, reading of special literature, self-making of informational materials and medical screening. As kinds of activities with negative effect were marked Internet-projects, social advertising, volunteer’s activities and discussions. The results of this study were presented during educational courses for doctors and teachers. The aim of the study in 2017 year was evaluating the effectiveness of the implementation of this recommendations. The program of the research included the survey of teenagers and the study of epidemiological data. The results showed the raising of the coverage of teenagers by effective preventive НАУЧНЫЕ ВЕДОМОСТИ |\"Ъ Серия Медицина. Фармация. 2018. Том 41, No 4 641 activities, decreasing of incidence of STI and reducing the proportion of young people among newly diagnosed patients. Ключевые слова: половые инфекции, молодежь, профилактика, заболеваемость, оценка эффективности","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80961270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of value of blood-brain barrier of acute lymphoblastic leukemia and neuroleukemia 急性淋巴细胞白血病与神经细胞白血病血脑屏障的价值分析
Pub Date : 2018-12-30 DOI: 10.18413/2075-4728-2018-41-4-568-575
I. A. Dzhanybekova
{"title":"Analysis of value of blood-brain barrier of acute lymphoblastic leukemia and neuroleukemia","authors":"I. A. Dzhanybekova","doi":"10.18413/2075-4728-2018-41-4-568-575","DOIUrl":"https://doi.org/10.18413/2075-4728-2018-41-4-568-575","url":null,"abstract":"","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86614495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Modern aspects of pathogenesis acute hematogenous osteomyelitis 急性血液性骨髓炎发病机制的现代方面
Pub Date : 2018-12-30 DOI: 10.18413/2075-4728-2018-41-4-539-546
S. V. Kostin, V. P. Gavriliuk, D. A. Severinov, M. I. Statina
{"title":"Modern aspects of pathogenesis acute hematogenous osteomyelitis","authors":"S. V. Kostin, V. P. Gavriliuk, D. A. Severinov, M. I. Statina","doi":"10.18413/2075-4728-2018-41-4-539-546","DOIUrl":"https://doi.org/10.18413/2075-4728-2018-41-4-539-546","url":null,"abstract":"","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73852982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The impact of communication doctor – patient's parents on the level of parental compliance in the treatment of children with chronic gastroduodenal pathology associated with Helicobacter pylori 医患父母沟通对幽门螺杆菌相关慢性胃十二指肠病理患儿治疗依从性的影响
Pub Date : 2018-12-30 DOI: 10.18413/2075-4728-2018-41-4-616-624
A. Barinova, A. V. Nalyotov, S. V. Nalyotov
The aim of the study was to determine the influence of communication between the doctor - patient's parents on the level of parental compliance in families of children suffering from chronic gastroduodenal pathology associated with H. pylori. 103 children of school age suffering from chronicgastroduodenal pathology associated with H. pylori were examined. The anti-H. pylori therapy scheme was prescribed for all children. The decrease in parental compliance was noted in more than 2/3 of the surveyed families. The low level of communication between the doctor and the patient's parents was established. The doctor's dialogue with the parents of a sick child takes place in conditions of limited time provided to the specialist during the consultation. Establishment of interpersonal relationships in the "doctor- patient's parents" system, working with parents, aimed at explaining the essence of the disease, the consequences of the disease, treatment tactics are an important stage in the therapy of a sick child. дети, хроническая Helicobacter
本研究的目的是确定在患有幽门螺杆菌相关慢性胃十二指肠病理的儿童家庭中,医患父母之间的沟通对父母依从性水平的影响。本文对103名患有幽门螺杆菌相关慢性胃十二指肠病理的学龄儿童进行了检查。anti-H。所有儿童均采用幽门螺杆菌治疗方案。超过三分之二的被调查家庭注意到父母依从性的下降。医生和病人父母之间的低水平沟通是确定的。医生与患儿父母的对话是在会诊期间提供给专家的有限时间内进行的。在“医患家长”体系中建立人际关系,与家长合作,旨在解释疾病的本质、疾病的后果、治疗策略,是患儿治疗的重要阶段。дети, хроническая幽门螺杆菌
{"title":"The impact of communication doctor – patient's parents on the level of parental compliance in the treatment of children with chronic gastroduodenal pathology associated with Helicobacter pylori","authors":"A. Barinova, A. V. Nalyotov, S. V. Nalyotov","doi":"10.18413/2075-4728-2018-41-4-616-624","DOIUrl":"https://doi.org/10.18413/2075-4728-2018-41-4-616-624","url":null,"abstract":"The aim of the study was to determine the influence of communication between the doctor - patient's parents on the level of parental compliance in families of children suffering from chronic gastroduodenal pathology associated with H. pylori. 103 children of school age suffering from chronicgastroduodenal pathology associated with H. pylori were examined. The anti-H. pylori therapy scheme was prescribed for all children. The decrease in parental compliance was noted in more than 2/3 of the surveyed families. The low level of communication between the doctor and the patient's parents was established. The doctor's dialogue with the parents of a sick child takes place in conditions of limited time provided to the specialist during the consultation. Establishment of interpersonal relationships in the \"doctor- patient's parents\" system, working with parents, aimed at explaining the essence of the disease, the consequences of the disease, treatment tactics are an important stage in the therapy of a sick child. дети, хроническая Helicobacter","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79192221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Belgorod State University Scientific bulletin Medicine Pharmacy
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1