Pub Date : 2018-12-30DOI: 10.18413/2075-4728-2018-41-4-659-671
M. V. Krys'ko, Saint-Petersburg State Chemical, Yu. V. Slustovskaya, O. Strelova, V. Kuklin
The objective of the present study was to test the developed methods of enzymatic hydrolysis on natural and dyed fur (hair) and analyze the effect of bleaching on the results of a chemical toxicological analysis. The experiments were carried out with the used laboratory animals (red hair and black hair female guinea pigs) that had been daily given a diphenhydramine solution per os during 6 months preceding the study. It was shown that natural black and red hair (fur) have a similar composition of endogenous substances. Bleaching is a process of gaining much lighter hair color than natural one. And along with this, there is a destruction of natural hair pigment. The effect of the bleaching does not affect the background level of endogenous substances and does not interfere with the further determination of the model drug substance. Methods of enzymatic hydrolysis can be used to isolate substances from both natural colored and dyed hair (fur). The degree of extraction of diphenhydramine, a model drug substance, from bleached fur was 1.5-2 times higher than the degree of extraction of it from natural colored, which should be take into consideration when interpreting the results. This study can be used to diagnose the use of narcotic drugs and psychotropic substances. It is planned to conduct further studies on sectional analysis of hair. of synthetic psychoactive substances and their metabolites in and nails by liquid chromatography methods with mass spec-trometric detection] Informacionnoe Стрелова О.Ю., Сивакова М.А. 2017. Применение методики
{"title":"Approbation of the method of enzymatic hydrolysis on natural and dyed hair for the extraction of medicinal substances","authors":"M. V. Krys'ko, Saint-Petersburg State Chemical, Yu. V. Slustovskaya, O. Strelova, V. Kuklin","doi":"10.18413/2075-4728-2018-41-4-659-671","DOIUrl":"https://doi.org/10.18413/2075-4728-2018-41-4-659-671","url":null,"abstract":"The objective of the present study was to test the developed methods of enzymatic hydrolysis on natural and dyed fur (hair) and analyze the effect of bleaching on the results of a chemical toxicological analysis. The experiments were carried out with the used laboratory animals (red hair and black hair female guinea pigs) that had been daily given a diphenhydramine solution per os during 6 months preceding the study. It was shown that natural black and red hair (fur) have a similar composition of endogenous substances. Bleaching is a process of gaining much lighter hair color than natural one. And along with this, there is a destruction of natural hair pigment. The effect of the bleaching does not affect the background level of endogenous substances and does not interfere with the further determination of the model drug substance. Methods of enzymatic hydrolysis can be used to isolate substances from both natural colored and dyed hair (fur). The degree of extraction of diphenhydramine, a model drug substance, from bleached fur was 1.5-2 times higher than the degree of extraction of it from natural colored, which should be take into consideration when interpreting the results. This study can be used to diagnose the use of narcotic drugs and psychotropic substances. It is planned to conduct further studies on sectional analysis of hair. of synthetic psychoactive substances and their metabolites in and nails by liquid chromatography methods with mass spec-trometric detection] Informacionnoe Стрелова О.Ю., Сивакова М.А. 2017. Применение методики","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73540817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-30DOI: 10.18413/2075-4728-2018-41-4-687-702
O. V. Trineeva, A. J. Halahakun, A. I. Slivkin
{"title":"Development and validation of spectrophotometric quantitative determination of terpene-indole alkaloids (for example, vincristine sulfate and vinblastine sulfate)","authors":"O. V. Trineeva, A. J. Halahakun, A. I. Slivkin","doi":"10.18413/2075-4728-2018-41-4-687-702","DOIUrl":"https://doi.org/10.18413/2075-4728-2018-41-4-687-702","url":null,"abstract":"","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82511076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-30DOI: 10.18413/2075-4728-2018-41-4-672-686
D. D. Siukaeva, Saint-Petersburg State Chemical, I. Narkevich, O. D. Nemyatych, I. I. Basakina
The results of the analysis of the hospital segment of the national and regional markets in the period from 2013 to 2017 are presented in the paper. It was established that volume of the Russian pharmaceutical market for hospital purchases grew by 42 % in value terms and by 8 % in physical terms over the study period. At the same time, the share of drugs represented by foreign manufacturers decreased by 5 % in value terms and by 2 % in physical terms, respectively. It has been established that in the given research conditions the group J «Antimicrobial drugs of systemic action» is the leader in the overall structure of national procurement, covering more than 30.0-35.5 % in value and more than 26.0-30.0 than 50 % of the range of antibacterial drugs. It is shown that in the structure of procurement, leading positions in terms of value were noted for foreign manufacturers, in natural units, domestic two producers play a leading role (more than 40 % of the assortment) both in the national and regional markets. At the same time, the vaccine for the prevention of pneumococcal infections (6-8 %) leads in cost terms, in natural units, ceftriaxone (about 20 %).
{"title":"Analysis of hospital purchases of antimicrobial drugs in the framework of the pharmaceutical market the North-Western Federal District","authors":"D. D. Siukaeva, Saint-Petersburg State Chemical, I. Narkevich, O. D. Nemyatych, I. I. Basakina","doi":"10.18413/2075-4728-2018-41-4-672-686","DOIUrl":"https://doi.org/10.18413/2075-4728-2018-41-4-672-686","url":null,"abstract":"The results of the analysis of the hospital segment of the national and regional markets in the period from 2013 to 2017 are presented in the paper. It was established that volume of the Russian pharmaceutical market for hospital purchases grew by 42 % in value terms and by 8 % in physical terms over the study period. At the same time, the share of drugs represented by foreign manufacturers decreased by 5 % in value terms and by 2 % in physical terms, respectively. It has been established that in the given research conditions the group J «Antimicrobial drugs of systemic action» is the leader in the overall structure of national procurement, covering more than 30.0-35.5 % in value and more than 26.0-30.0 than 50 % of the range of antibacterial drugs. It is shown that in the structure of procurement, leading positions in terms of value were noted for foreign manufacturers, in natural units, domestic two producers play a leading role (more than 40 % of the assortment) both in the national and regional markets. At the same time, the vaccine for the prevention of pneumococcal infections (6-8 %) leads in cost terms, in natural units, ceftriaxone (about 20 %).","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81313446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-30DOI: 10.18413/2075-4728-2018-41-4-600-615
N. Goroshko, E. Emelyanova, N. Nikiforova, Biotechnology “Vector”
{"title":"Novosibirsk as a center of regional medical tourism: potential and implementation aspects","authors":"N. Goroshko, E. Emelyanova, N. Nikiforova, Biotechnology “Vector”","doi":"10.18413/2075-4728-2018-41-4-600-615","DOIUrl":"https://doi.org/10.18413/2075-4728-2018-41-4-600-615","url":null,"abstract":"","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":"146 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77767695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-30DOI: 10.18413/2075-4728-2018-41-4-584-590
V. F. Kulikovsky, Y. A. Khoschenko, T. A. Nachetova, A. Nagorny
There are the results of the second round of accreditation of the graduates in the field of general medicine in Belgorod National Research University. The article explains reasons for using such indicators in assessing of professional skills quality as the average score in the accredited group for each station, percentage of persons attaining the highest grades, identification of the nature of the most frequent errors. In 2018 the graduates have higher rates of correctly implemented procedures than received in 2017 at such stations as emergency medical care ((95.79±1.70 % VS 86.63±2.95 %, Р<0.05), urgent medical care (98.34±1.08 % VS 88.77±2.76 %, Р<0.05), physical examination of cardiovascular system (97.10±1.42 % VS 90.84±2.52 %, Р<0.05). This article illustrates that raised level of skills and knowledge in 2018 is due to increasing the time available for preparations which became possible through the development of tutoring movement, students' participation in practical training competitions and the opening of The Center For Simulation Training And Assessment Of Professional Qualifications Of The Department Of Medical And Pharmaceutical Supplementary Education, Certification And Accreditation. It is stressed the need to increase the number of systematic practical skills training in simulated conditions for students of the Medical Institute. аккредитация, качество образования, практикоориентированная
这是别尔哥罗德国立研究型大学全科医学毕业生第二轮认证的结果。文章解释了在评估专业技能质量时使用这些指标的原因,如每个站点在认可组中的平均分数,获得最高分数的人的百分比,以及识别最常见错误的性质。2018年毕业生在急诊(95.79±1.70% VS 86.63±2.95%,Р<0.05)、急诊(98.34±1.08% VS 88.77±2.76%,Р<0.05)、心血管系统体检(97.10±1.42% VS 90.84±2.52%,Р<0.05)等科室的程序正确执行率均高于2017年。本文说明,2018年技能和知识水平的提高是由于增加了可用于准备的时间,这是通过发展辅导运动、学生参加实践培训比赛以及开设医学和制药补充教育、认证和认可系专业资格模拟培训和评估中心而成为可能的。强调有必要增加医学院学生在模拟条件下的系统实践技能训练的数量。аккредитация,качествообразования,практикоориентированная
{"title":"Analysis of the results of primary accreditation of the graduates in the field of general medicine in the center of simulation training and assessment of professional skills of Belgorod National Research Universit","authors":"V. F. Kulikovsky, Y. A. Khoschenko, T. A. Nachetova, A. Nagorny","doi":"10.18413/2075-4728-2018-41-4-584-590","DOIUrl":"https://doi.org/10.18413/2075-4728-2018-41-4-584-590","url":null,"abstract":"There are the results of the second round of accreditation of the graduates in the field of general medicine in Belgorod National Research University. The article explains reasons for using such indicators in assessing of professional skills quality as the average score in the accredited group for each station, percentage of persons attaining the highest grades, identification of the nature of the most frequent errors. In 2018 the graduates have higher rates of correctly implemented procedures than received in 2017 at such stations as emergency medical care ((95.79±1.70 % VS 86.63±2.95 %, Р<0.05), urgent medical care (98.34±1.08 % VS 88.77±2.76 %, Р<0.05), physical examination of cardiovascular system (97.10±1.42 % VS 90.84±2.52 %, Р<0.05). This article illustrates that raised level of skills and knowledge in 2018 is due to increasing the time available for preparations which became possible through the development of tutoring movement, students' participation in practical training competitions and the opening of The Center For Simulation Training And Assessment Of Professional Qualifications Of The Department Of Medical And Pharmaceutical Supplementary Education, Certification And Accreditation. It is stressed the need to increase the number of systematic practical skills training in simulated conditions for students of the Medical Institute. аккредитация, качество образования, практикоориентированная","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":"291 1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73165964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-30DOI: 10.18413/2075-4728-2018-41-4-558-567
V. I. Vishnevskij, I. I. Mironenko, O. Demyanenko
149 patients with community-acquired pneumonia, the influence of the antioxidant tiotriazoline on the state of cellular and humoral immunity was studied. Studies have shown that out-of-hospital pneumonia occurs against the background of secondary immunodeficiency, which is manifested by a decrease in the total circulating T-lymphocytes and their subpopulations: NK-cells, T-helper cells, T-suppressors, Ig A and Ig G increase in Ig M decrease. Tiotriazoline in the complex therapy of patients with community-acquired pneumonia is accompanied by a decrease in both total T-lymphocytopenia and their subpopulations against the background of an increase in the content of immunoglobulins of class Ig M reduction in immunoglobulin classes Ig A and Ig G. of changes in cellular and humoral immunity in patients with community-acquired against the background of course treatment with thiotriazoline
{"title":"The effect of thiotriazoline on the state of cellular and humoral immunity in patients with community-acquired pneumonia","authors":"V. I. Vishnevskij, I. I. Mironenko, O. Demyanenko","doi":"10.18413/2075-4728-2018-41-4-558-567","DOIUrl":"https://doi.org/10.18413/2075-4728-2018-41-4-558-567","url":null,"abstract":"149 patients with community-acquired pneumonia, the influence of the antioxidant tiotriazoline on the state of cellular and humoral immunity was studied. Studies have shown that out-of-hospital pneumonia occurs against the background of secondary immunodeficiency, which is manifested by a decrease in the total circulating T-lymphocytes and their subpopulations: NK-cells, T-helper cells, T-suppressors, Ig A and Ig G increase in Ig M decrease. Tiotriazoline in the complex therapy of patients with community-acquired pneumonia is accompanied by a decrease in both total T-lymphocytopenia and their subpopulations against the background of an increase in the content of immunoglobulins of class Ig M reduction in immunoglobulin classes Ig A and Ig G. of changes in cellular and humoral immunity in patients with community-acquired against the background of course treatment with thiotriazoline","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":"77 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83880335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-30DOI: 10.18413/2075-4728-2018-41-4-640-651
A. G. Lastovetsky, V. I. Timoshilov
Sexually transmitted infections (STI) are one of the main medical and social problems of young people. The base of their prevention is formed by educational events for youth. In 2014 it was conducted a study, which shows a positive preventive effects of lectures and consults of doctors, watching of educational video, reading of special literature, self-making of informational materials and medical screening. As kinds of activities with negative effect were marked Internet-projects, social advertising, volunteer’s activities and discussions. The results of this study were presented during educational courses for doctors and teachers. The aim of the study in 2017 year was evaluating the effectiveness of the implementation of this recommendations. The program of the research included the survey of teenagers and the study of epidemiological data. The results showed the raising of the coverage of teenagers by effective preventive НАУЧНЫЕ ВЕДОМОСТИ |"Ъ Серия Медицина. Фармация. 2018. Том 41, No 4 641 activities, decreasing of incidence of STI and reducing the proportion of young people among newly diagnosed patients. Ключевые слова: половые инфекции, молодежь, профилактика, заболеваемость, оценка эффективности
性传播感染是年轻人面临的主要医疗和社会问题之一。预防这些疾病的基础是通过青少年教育活动形成的。2014年进行的一项研究表明,医生的讲座和咨询、观看教育视频、阅读专题文献、自编信息资料和医学筛查具有积极的预防效果。网络项目、社会广告、志愿者活动、讨论等活动对学生产生了负面影响。本研究的结果在医生和教师的教育课程中提出。2017年研究的目的是评估实施这些建议的有效性。研究项目包括青少年调查和流行病学资料研究。结果表明,有效的预防措施提高了青少年的覆盖率НАУЧНЫЕ ВЕДОМОСТИ |"Ъ Серия Медицина。Фармация。2018. Том 41,第4 641号活动,降低性传播感染的发病率,降低新诊断患者中年轻人的比例。Ключевыеслова:половыеинфекци,имолодежь,профилактика,заболеваемость,оценкаэффективности
{"title":"Complex evaluation of the effect of prevention of sexually transmitted infections among young people of Kursk Region","authors":"A. G. Lastovetsky, V. I. Timoshilov","doi":"10.18413/2075-4728-2018-41-4-640-651","DOIUrl":"https://doi.org/10.18413/2075-4728-2018-41-4-640-651","url":null,"abstract":"Sexually transmitted infections (STI) are one of the main medical and social problems of young people. The base of their prevention is formed by educational events for youth. In 2014 it was conducted a study, which shows a positive preventive effects of lectures and consults of doctors, watching of educational video, reading of special literature, self-making of informational materials and medical screening. As kinds of activities with negative effect were marked Internet-projects, social advertising, volunteer’s activities and discussions. The results of this study were presented during educational courses for doctors and teachers. The aim of the study in 2017 year was evaluating the effectiveness of the implementation of this recommendations. The program of the research included the survey of teenagers and the study of epidemiological data. The results showed the raising of the coverage of teenagers by effective preventive НАУЧНЫЕ ВЕДОМОСТИ |\"Ъ Серия Медицина. Фармация. 2018. Том 41, No 4 641 activities, decreasing of incidence of STI and reducing the proportion of young people among newly diagnosed patients. Ключевые слова: половые инфекции, молодежь, профилактика, заболеваемость, оценка эффективности","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":"61 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80961270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-30DOI: 10.18413/2075-4728-2018-41-4-568-575
I. A. Dzhanybekova
{"title":"Analysis of value of blood-brain barrier of acute lymphoblastic leukemia and neuroleukemia","authors":"I. A. Dzhanybekova","doi":"10.18413/2075-4728-2018-41-4-568-575","DOIUrl":"https://doi.org/10.18413/2075-4728-2018-41-4-568-575","url":null,"abstract":"","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86614495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-30DOI: 10.18413/2075-4728-2018-41-4-539-546
S. V. Kostin, V. P. Gavriliuk, D. A. Severinov, M. I. Statina
{"title":"Modern aspects of pathogenesis acute hematogenous osteomyelitis","authors":"S. V. Kostin, V. P. Gavriliuk, D. A. Severinov, M. I. Statina","doi":"10.18413/2075-4728-2018-41-4-539-546","DOIUrl":"https://doi.org/10.18413/2075-4728-2018-41-4-539-546","url":null,"abstract":"","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73852982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-12-30DOI: 10.18413/2075-4728-2018-41-4-616-624
A. Barinova, A. V. Nalyotov, S. V. Nalyotov
The aim of the study was to determine the influence of communication between the doctor - patient's parents on the level of parental compliance in families of children suffering from chronic gastroduodenal pathology associated with H. pylori. 103 children of school age suffering from chronicgastroduodenal pathology associated with H. pylori were examined. The anti-H. pylori therapy scheme was prescribed for all children. The decrease in parental compliance was noted in more than 2/3 of the surveyed families. The low level of communication between the doctor and the patient's parents was established. The doctor's dialogue with the parents of a sick child takes place in conditions of limited time provided to the specialist during the consultation. Establishment of interpersonal relationships in the "doctor- patient's parents" system, working with parents, aimed at explaining the essence of the disease, the consequences of the disease, treatment tactics are an important stage in the therapy of a sick child. дети, хроническая Helicobacter
{"title":"The impact of communication doctor – patient's parents on the level of parental compliance in the treatment of children with chronic gastroduodenal pathology associated with Helicobacter pylori","authors":"A. Barinova, A. V. Nalyotov, S. V. Nalyotov","doi":"10.18413/2075-4728-2018-41-4-616-624","DOIUrl":"https://doi.org/10.18413/2075-4728-2018-41-4-616-624","url":null,"abstract":"The aim of the study was to determine the influence of communication between the doctor - patient's parents on the level of parental compliance in families of children suffering from chronic gastroduodenal pathology associated with H. pylori. 103 children of school age suffering from chronicgastroduodenal pathology associated with H. pylori were examined. The anti-H. pylori therapy scheme was prescribed for all children. The decrease in parental compliance was noted in more than 2/3 of the surveyed families. The low level of communication between the doctor and the patient's parents was established. The doctor's dialogue with the parents of a sick child takes place in conditions of limited time provided to the specialist during the consultation. Establishment of interpersonal relationships in the \"doctor- patient's parents\" system, working with parents, aimed at explaining the essence of the disease, the consequences of the disease, treatment tactics are an important stage in the therapy of a sick child. дети, хроническая Helicobacter","PeriodicalId":8785,"journal":{"name":"Belgorod State University Scientific bulletin Medicine Pharmacy","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79192221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}