Pub Date : 2023-11-22DOI: 10.20473/bikk.v35.3.2023.226-230
Septiana Widyantari, Dinda Rozita Maharani, Kinanthi Koesandrini, T. Setyaningrum
Background: Human Papilloma Virus (HPV) 6 and 11 are most commonly detected in genital warts, known as condyloma acuminata. Bacterial vaginosis (BV) is the most frequent vaginal infection in women aged 15 to 44 years. There may be an association between condyloma acuminata and BV. Purpose : To report a case of condyloma accuminata in a pregnant patient with combination bacterial vaginosis. Case: A 24-year-old, 8-week pregnant woman came to the clinic with a chief complaint of multiple warts in the genital area since 3 months prior to the hospital visit. The bumps on the vulva were small, and at first only one but then spread to surrounding areas. The bumps were itchy and painful. Complaints of vaginal discharge or fluor albus of yellowish-white gray color, accompanied by itchy and a fishy odor that appeared three months ago and worsened in the last two weeks. Examination results led to the diagnosis of condyloma acuminata and BV in the patient. The patient's condition improved after being given 90% trichloroacetic acid (TCA), electrocautery, and metronidazole. Discussion: Pregnancy decreases cell-mediated immunity, which may decrease immune tolerance and local physiologic changes and ultimately increase HPV infection in pregnancy. HPV infection is associated with a vaginal microbiota imbalance, making pregnant women prone to vaginal infections such as BV. Conclusion: Condyloma accuminata and BV often occur in high-risk groups for sexually transmitted infections, one of which is pregnant women. It is necessary to screen for sexually transmitted infections (STIs) in pregnant women to prevent complications.
{"title":"Condyloma Accuminata In Pregnancy Overlapping With Bacterial Vaginosis","authors":"Septiana Widyantari, Dinda Rozita Maharani, Kinanthi Koesandrini, T. Setyaningrum","doi":"10.20473/bikk.v35.3.2023.226-230","DOIUrl":"https://doi.org/10.20473/bikk.v35.3.2023.226-230","url":null,"abstract":"Background: Human Papilloma Virus (HPV) 6 and 11 are most commonly detected in genital warts, known as condyloma acuminata. Bacterial vaginosis (BV) is the most frequent vaginal infection in women aged 15 to 44 years. There may be an association between condyloma acuminata and BV. Purpose : To report a case of condyloma accuminata in a pregnant patient with combination bacterial vaginosis. Case: A 24-year-old, 8-week pregnant woman came to the clinic with a chief complaint of multiple warts in the genital area since 3 months prior to the hospital visit. The bumps on the vulva were small, and at first only one but then spread to surrounding areas. The bumps were itchy and painful. Complaints of vaginal discharge or fluor albus of yellowish-white gray color, accompanied by itchy and a fishy odor that appeared three months ago and worsened in the last two weeks. Examination results led to the diagnosis of condyloma acuminata and BV in the patient. The patient's condition improved after being given 90% trichloroacetic acid (TCA), electrocautery, and metronidazole. Discussion: Pregnancy decreases cell-mediated immunity, which may decrease immune tolerance and local physiologic changes and ultimately increase HPV infection in pregnancy. HPV infection is associated with a vaginal microbiota imbalance, making pregnant women prone to vaginal infections such as BV. Conclusion: Condyloma accuminata and BV often occur in high-risk groups for sexually transmitted infections, one of which is pregnant women. It is necessary to screen for sexually transmitted infections (STIs) in pregnant women to prevent complications.","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":"27 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139248490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-31DOI: 10.20473/bikk.v35.2.2023.130-135
Arie Hidayati, Nanda Earlia, Ninda Sari, Vella, Mimi Maulida, C. W. Asrizal
Background: Infantile hemangiomas (IH) are the most prevalent benign tumors in children, predominantly in girls. Most IH cases do not require treatment due to spontaneous involution, but 10% of cases do require early treatment due to size, location, and complications. Purpose: This study tried to define the profile, clinical aspects, and therapy of IH in Dr. Zainoel Abidin General Hospital, Banda Aceh. Methods: A descriptive approach using a retrospective analysis employing secondary data from the outpatient clinic's patient registration book. This study included all new cases of infantile hemangioma at the outpatient clinic general hospital between 2013 and 2021. Result: A total of 105 patients were involved in this study. The majority of IH patients (59%) were under the age of one year, with 64 female patients (61%) making the most visits to the pediatric clinic in 2017, 2018, and 2019 (77.1%). The most prevalent clinical features of skin lesions were nodules in 69 individuals (65.7%), and the most common site was the facial region (13.3%) in 44 patients. In 20 individuals, a combination of propanolol and oral corticosteroids was used as the most effective treatment strategy (19% ). Conclusion: Infantile hemangiomas is the most frequently reported benign tumor in children. Females are more likely than males to develop IH. The majority of IH is minor and normally resolves on its own without therapy. However, certain rare kinds of IH require clinician attention and systematic treatment.
{"title":"The Profiles of Infantile Hemangiomas Patients","authors":"Arie Hidayati, Nanda Earlia, Ninda Sari, Vella, Mimi Maulida, C. W. Asrizal","doi":"10.20473/bikk.v35.2.2023.130-135","DOIUrl":"https://doi.org/10.20473/bikk.v35.2.2023.130-135","url":null,"abstract":"Background: Infantile hemangiomas (IH) are the most prevalent benign tumors in children, predominantly in girls. Most IH cases do not require treatment due to spontaneous involution, but 10% of cases do require early treatment due to size, location, and complications. Purpose: This study tried to define the profile, clinical aspects, and therapy of IH in Dr. Zainoel Abidin General Hospital, Banda Aceh. Methods: A descriptive approach using a retrospective analysis employing secondary data from the outpatient clinic's patient registration book. This study included all new cases of infantile hemangioma at the outpatient clinic general hospital between 2013 and 2021. Result: A total of 105 patients were involved in this study. The majority of IH patients (59%) were under the age of one year, with 64 female patients (61%) making the most visits to the pediatric clinic in 2017, 2018, and 2019 (77.1%). The most prevalent clinical features of skin lesions were nodules in 69 individuals (65.7%), and the most common site was the facial region (13.3%) in 44 patients. In 20 individuals, a combination of propanolol and oral corticosteroids was used as the most effective treatment strategy (19% ). Conclusion: Infantile hemangiomas is the most frequently reported benign tumor in children. Females are more likely than males to develop IH. The majority of IH is minor and normally resolves on its own without therapy. However, certain rare kinds of IH require clinician attention and systematic treatment.","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85846707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-31DOI: 10.20473/bikk.v35.2.2023.126-129
Albertus Alarik L., D. Indiastuti, L. Astari, T. Setyaningrum
Background: Acne vulgaris is a disease in the form of chronic inflammation of the pilosebaceous follicles with multifactorial causes. Acne vulgaris is a very common skin disease with a prevalence of 85% in the age range of 18-25 years. There are aggravating factors that can exacerbate acne vulgaris, including hormonal factors. However, the study about how strong the effects of hormonal factors and on acne severity is really limited. Purpose: The objective of this research is to determine how strong hormonal factors contribute on the severity of acne vulgaris. Methods: This was a cross-sectional retrospective study using secondary data obtained from 199 patients at the Dermatology and Venereology Outpatient Unit of RSUD Dr. Soetomo from January- December 2019. The data were analyzed using SPSS with regression analysis.Result: Hormonal factors significantly influenced the degree of acne vulgaris severity (P-value=0.030). Based on the logistic regression model, it can be found that hormonal factors influence the degree of acne vulgaris by 70% Conclusion: The effect of hormonal factors on the severity of acne vulgaris is 70%.
{"title":"The Effects of Hormonal Factor on the Degree of Acne Vulgaris Severity","authors":"Albertus Alarik L., D. Indiastuti, L. Astari, T. Setyaningrum","doi":"10.20473/bikk.v35.2.2023.126-129","DOIUrl":"https://doi.org/10.20473/bikk.v35.2.2023.126-129","url":null,"abstract":"Background: Acne vulgaris is a disease in the form of chronic inflammation of the pilosebaceous follicles with multifactorial causes. Acne vulgaris is a very common skin disease with a prevalence of 85% in the age range of 18-25 years. There are aggravating factors that can exacerbate acne vulgaris, including hormonal factors. However, the study about how strong the effects of hormonal factors and on acne severity is really limited. Purpose: The objective of this research is to determine how strong hormonal factors contribute on the severity of acne vulgaris. Methods: This was a cross-sectional retrospective study using secondary data obtained from 199 patients at the Dermatology and Venereology Outpatient Unit of RSUD Dr. Soetomo from January- December 2019. The data were analyzed using SPSS with regression analysis.Result: Hormonal factors significantly influenced the degree of acne vulgaris severity (P-value=0.030). Based on the logistic regression model, it can be found that hormonal factors influence the degree of acne vulgaris by 70% Conclusion: The effect of hormonal factors on the severity of acne vulgaris is 70%.","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91241181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Skin tags or acrochordons are benign fibroepithelioma skin tumors with soft consistency, usually pedunculated, primarily originating from the dermis. High levels of blood sugar and a high lipid profile are risk factors for inflammation and hormonal imbalance, which can contribute to the development of skin tags. Purpose: The objective of this study is to identify the association between blood sugar and lipid profile with skin tags. Methods: This study is a cross-sectional study conducted from April to August 2019 at the Dermatovenereology and Endocrine Policlinic, Dr. Zainoel Abidin General Hospital, Banda Aceh. The sampling method of this study was consecutive sampling with 60 samples that met the inclusion and exclusion criteria. A blood glucose, lipid profile, and skin tag examination was conducted on all subjects. Result: The majority of the subjects are women (61.5%), have an average age of 41-50 years old (43.3%), are obese (41.7%), and have one to five lessions of 1-5 (53.3%). There was a significant correlation between blood glucose, 2 hours post-prandial, total cholesterol, triglyceride, high-density lipoprotein (HDL), and low-density lipoprotein (LDL) levels with skin tags with Spearman’s correlation values of 0.645, 0.645, 0.794, 0.704, 0.606, and 0.606 consecutively. Conclusion: A high level of blood sugar and lipid profile, whether it is total cholesterol, triglycerides, HDL, or LDL level, can contribute to the development of skin tags.
{"title":"The Correlation between Blood Glucose and Lipid Profile with Skin tag","authors":"Wahyu Lestari, Sulamsih, Cut Yunita, Hendra Zufry, Sitti Hajar","doi":"10.20473/bikk.v35.2.2023.136-141","DOIUrl":"https://doi.org/10.20473/bikk.v35.2.2023.136-141","url":null,"abstract":"Background: Skin tags or acrochordons are benign fibroepithelioma skin tumors with soft consistency, usually pedunculated, primarily originating from the dermis. High levels of blood sugar and a high lipid profile are risk factors for inflammation and hormonal imbalance, which can contribute to the development of skin tags. Purpose: The objective of this study is to identify the association between blood sugar and lipid profile with skin tags. Methods: This study is a cross-sectional study conducted from April to August 2019 at the Dermatovenereology and Endocrine Policlinic, Dr. Zainoel Abidin General Hospital, Banda Aceh. The sampling method of this study was consecutive sampling with 60 samples that met the inclusion and exclusion criteria. A blood glucose, lipid profile, and skin tag examination was conducted on all subjects. Result: The majority of the subjects are women (61.5%), have an average age of 41-50 years old (43.3%), are obese (41.7%), and have one to five lessions of 1-5 (53.3%). There was a significant correlation between blood glucose, 2 hours post-prandial, total cholesterol, triglyceride, high-density lipoprotein (HDL), and low-density lipoprotein (LDL) levels with skin tags with Spearman’s correlation values of 0.645, 0.645, 0.794, 0.704, 0.606, and 0.606 consecutively. Conclusion: A high level of blood sugar and lipid profile, whether it is total cholesterol, triglycerides, HDL, or LDL level, can contribute to the development of skin tags.","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89846517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-31DOI: 10.20473/bikk.v35.2.2023.163-167
Nandya Dwizella, Nevristia Pratama
Background: Pemphigus disease, especsially Pemphigus Vulgaris (PV), is an autoimmune disease resulting in blisters on the skin and mucosa due to autoantibodies attacking desmogleins (DSG) 1 and 3. Autoimmunity development in PV may be idiopathic or induced by neoplasms, drugs, infections, or inflammatory processes. Besides affecting the respiratory tract, COVID-19 may also affect other systems, such as the skin. The pathogenesis of autoimmune diseases and COVID-19 have similarities, which is an overreaction of the immune system. Purpose: To report a case about the association between PV autoimmune disease and COVID-19. Case: A 30-year-old woman presented with full-body pain and ulcers. Three days before the skin lesions, the patient complained of a mild cough, and the SARS-CoV-2 examination was positive. The patient was treated with systemic and topical corticosteroids along with broad-spectrum antivirals. The patient was discharged with an improved lesion condition and a negative SARS-CoV-2 PCR on day 5 of treatment. Discussion: Prolonged viral infection or viral infection itself, such as COVID-19 can cause immune system dysregulation leading to autoimmune skin lesions with different mechanisms. The use of corticosteroids or immunosuppressants in autoimmune diseases increases the risk of COVID-19 infection in a pandemic. Conclusion: In the COVID-19 pandemic, COVID-19 and autoimmune diseases such as pemphigus vulgaris are interrelated with the presence of immune dysregulation leading to skin lesions
{"title":"Covid-19 In A Patient With Pemphigus: A Case Report","authors":"Nandya Dwizella, Nevristia Pratama","doi":"10.20473/bikk.v35.2.2023.163-167","DOIUrl":"https://doi.org/10.20473/bikk.v35.2.2023.163-167","url":null,"abstract":"Background: Pemphigus disease, especsially Pemphigus Vulgaris (PV), is an autoimmune disease resulting in blisters on the skin and mucosa due to autoantibodies attacking desmogleins (DSG) 1 and 3. Autoimmunity development in PV may be idiopathic or induced by neoplasms, drugs, infections, or inflammatory processes. Besides affecting the respiratory tract, COVID-19 may also affect other systems, such as the skin. The pathogenesis of autoimmune diseases and COVID-19 have similarities, which is an overreaction of the immune system. Purpose: To report a case about the association between PV autoimmune disease and COVID-19. Case: A 30-year-old woman presented with full-body pain and ulcers. Three days before the skin lesions, the patient complained of a mild cough, and the SARS-CoV-2 examination was positive. The patient was treated with systemic and topical corticosteroids along with broad-spectrum antivirals. The patient was discharged with an improved lesion condition and a negative SARS-CoV-2 PCR on day 5 of treatment. Discussion: Prolonged viral infection or viral infection itself, such as COVID-19 can cause immune system dysregulation leading to autoimmune skin lesions with different mechanisms. The use of corticosteroids or immunosuppressants in autoimmune diseases increases the risk of COVID-19 infection in a pandemic. Conclusion: In the COVID-19 pandemic, COVID-19 and autoimmune diseases such as pemphigus vulgaris are interrelated with the presence of immune dysregulation leading to skin lesions","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79646266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-31DOI: 10.20473/bikk.v35.2.2023.88-92
Maya Wardiana, Astindari, Evy Ervianti, A. Hidayati, D. Indramaya, P. Endraswari, B. Utomo, Dwi Murtiastutik
Background: Oral candidiasis (OC), frequently caused by Candida albicans, is the most common opportunistic infection in HIV/AIDS patients. Topical treatment for OC is limited. In vitro study revealed rosemary (Rosmarinus officinalis L.) essential oil has an antifungal effect. However, the essential oil is volatile and is not recommended to be applied to the skin and mucosa; therefore, emulsion gel (emulgel) is made. Purpose: This study was conducted to evaluate the antifungal activity of rosemary emulgel 6.25%, 25%, 37.5%, and 50% compared to nystatin. Methods: This study is an in vitro test using the disk diffusion method to d etermine the antifungal activity shown by the inhibitory zones of rosemary emulgel at 6.25%, 25%, 37.5%, and 50% compared to nystatin to stored isolates of C. albicans from HIV/AIDS patients with OC. Result: Rosemary emulgel 6.25% dan 25% did not show antifungal activity because no inhibitory zone was shown. The inhibitory zone diameter provided by rosemary emulgel 37.5%; 50%; and nystatin against C. albicans isolates were 3.17±3.763 mm; 7.00±4.107 mm; and 30.13±5.319 mm respectively. Significant differences in antifungal activity were shown by the inhibitory zone diameter provided between rosemary emulgel 37.5%, 50%, and nystatin (p<0,05). Conclusion: Rosemary emulgel 37.5% dan 50% had antifungal activity showed by the formation of inhibitory zone against Candida species isolates in disk diffusion method even though it was weaker compared to nystatin as a standard antifungal.
{"title":"Antifungal Activity of Rosemary (Rosmarinus officinalis L.) Emulsion Gel Compared to Nystatin on Candida albicans Stored Isolate from HIV/AIDS Patients with Oral Candidiasis","authors":"Maya Wardiana, Astindari, Evy Ervianti, A. Hidayati, D. Indramaya, P. Endraswari, B. Utomo, Dwi Murtiastutik","doi":"10.20473/bikk.v35.2.2023.88-92","DOIUrl":"https://doi.org/10.20473/bikk.v35.2.2023.88-92","url":null,"abstract":"Background: Oral candidiasis (OC), frequently caused by Candida albicans, is the most common opportunistic infection in HIV/AIDS patients. Topical treatment for OC is limited. In vitro study revealed rosemary (Rosmarinus officinalis L.) essential oil has an antifungal effect. However, the essential oil is volatile and is not recommended to be applied to the skin and mucosa; therefore, emulsion gel (emulgel) is made. Purpose: This study was conducted to evaluate the antifungal activity of rosemary emulgel 6.25%, 25%, 37.5%, and 50% compared to nystatin. Methods: This study is an in vitro test using the disk diffusion method to d etermine the antifungal activity shown by the inhibitory zones of rosemary emulgel at 6.25%, 25%, 37.5%, and 50% compared to nystatin to stored isolates of C. albicans from HIV/AIDS patients with OC. Result: Rosemary emulgel 6.25% dan 25% did not show antifungal activity because no inhibitory zone was shown. The inhibitory zone diameter provided by rosemary emulgel 37.5%; 50%; and nystatin against C. albicans isolates were 3.17±3.763 mm; 7.00±4.107 mm; and 30.13±5.319 mm respectively. Significant differences in antifungal activity were shown by the inhibitory zone diameter provided between rosemary emulgel 37.5%, 50%, and nystatin (p<0,05). Conclusion: Rosemary emulgel 37.5% dan 50% had antifungal activity showed by the formation of inhibitory zone against Candida species isolates in disk diffusion method even though it was weaker compared to nystatin as a standard antifungal.","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":"776 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85441092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-31DOI: 10.20473/bikk.v35.2.2023.148-157
D. Indramaya, Aprilin Krista Devi, Sawitri, B. Utomo, Izzatul Fithriyah, Dwi Murtiastutik, C. Prakoeswa, A. Hidayati
Background: Vitiligo is a long-term autoimmune disorder marked by the loss of melanocytes and the formation of white macules. Vitiligo can have an impact on the patient's look and quality of life. The Dermatology Life Quality Index (DLQI) is a questionnaire that analyzes the quality of life of skin patients in general, but it is not disease-specific. To assess the quality of life of vitiligo patients in Indonesia, a disease-specific instrument is required. Purpose: This study aims to analyze the validity and reliability of the Vitiligo Quality of Life (VitiQol) questionnaire in Indonesia and translate the VitiQol questionnaire into Indonesian. Methods: Using cross-sectional analytic observation, this study was performed on 39 participants with vitiligo at Dr. Soetomo Surabaya between December 2021 and January 2022. The investigation consisted of three phases: the Indonesian translation of VitiQol, testing for validity, and assessing reliability. Result: The VitiQol questionnaire is a valid and reliable questionnaire. Valid with a correlation coefficient between 0.40 and 0.80 and reliability close to perfection. There was a significant correlation between VitiQol and DLQI (r=0.511, p=0.001). Conclusion: According to the findings of this study, the Indonesian VitiQol is a valid and reliable instrument for measuring the life quality of vitiligo patients in Indonesia.
{"title":"Validation and Reliability of Indonesian Version of Vitiligo-Specific Health-Related Quality of Life Instrument (VITIQoL)","authors":"D. Indramaya, Aprilin Krista Devi, Sawitri, B. Utomo, Izzatul Fithriyah, Dwi Murtiastutik, C. Prakoeswa, A. Hidayati","doi":"10.20473/bikk.v35.2.2023.148-157","DOIUrl":"https://doi.org/10.20473/bikk.v35.2.2023.148-157","url":null,"abstract":"Background: Vitiligo is a long-term autoimmune disorder marked by the loss of melanocytes and the formation of white macules. Vitiligo can have an impact on the patient's look and quality of life. The Dermatology Life Quality Index (DLQI) is a questionnaire that analyzes the quality of life of skin patients in general, but it is not disease-specific. To assess the quality of life of vitiligo patients in Indonesia, a disease-specific instrument is required. Purpose: This study aims to analyze the validity and reliability of the Vitiligo Quality of Life (VitiQol) questionnaire in Indonesia and translate the VitiQol questionnaire into Indonesian. Methods: Using cross-sectional analytic observation, this study was performed on 39 participants with vitiligo at Dr. Soetomo Surabaya between December 2021 and January 2022. The investigation consisted of three phases: the Indonesian translation of VitiQol, testing for validity, and assessing reliability. Result: The VitiQol questionnaire is a valid and reliable questionnaire. Valid with a correlation coefficient between 0.40 and 0.80 and reliability close to perfection. There was a significant correlation between VitiQol and DLQI (r=0.511, p=0.001). Conclusion: According to the findings of this study, the Indonesian VitiQol is a valid and reliable instrument for measuring the life quality of vitiligo patients in Indonesia.","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":"74 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89527956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-31DOI: 10.20473/bikk.v35.2.2023.116-125
Aryani Adji, Alexandro Ivan Cahyadi
Background: Atopic dermatitis (AD) is a chronic skin inflammatory disease characterized by mild to severe itching, relapses, and mostly appears in infants and children. Although there have been current advances in the management of AD, satisfactory treatment has not been achieved. Purpose: To evaluate the treatment of patients with AD in order to provide better management. Methods: A retrospective study of newly diagnosed AD patients at the Allergy and Immunology Division of the Outpatient Unit, Dermatology and Venereology Clinic, Prof. Dr. R.D. Kandou Hospital Manado from 2019-2021. Result: Antihistamines were the most widely prescribed medication, administered to 108 patients of all patients’ visits, and 94 (87%) of them were given cetirizine (the most widely prescribed type). Emollients were used adequately; they included petroleum jelly in 82 patients (90.1%) and urea 10% cream in 9 patients (9.9%). Conclusion: There were 108 AD patients in Dermatology and Venereology Clinic, Prof. Dr. R.D. Kandou Hospital Manado from 2019-2021. Treatment with antihistamine and emollient therapy gave satisfactory results.
{"title":"Retrospective Study: Management of Atopic Dermatitis","authors":"Aryani Adji, Alexandro Ivan Cahyadi","doi":"10.20473/bikk.v35.2.2023.116-125","DOIUrl":"https://doi.org/10.20473/bikk.v35.2.2023.116-125","url":null,"abstract":"Background: Atopic dermatitis (AD) is a chronic skin inflammatory disease characterized by mild to severe itching, relapses, and mostly appears in infants and children. Although there have been current advances in the management of AD, satisfactory treatment has not been achieved. Purpose: To evaluate the treatment of patients with AD in order to provide better management. Methods: A retrospective study of newly diagnosed AD patients at the Allergy and Immunology Division of the Outpatient Unit, Dermatology and Venereology Clinic, Prof. Dr. R.D. Kandou Hospital Manado from 2019-2021. Result: Antihistamines were the most widely prescribed medication, administered to 108 patients of all patients’ visits, and 94 (87%) of them were given cetirizine (the most widely prescribed type). Emollients were used adequately; they included petroleum jelly in 82 patients (90.1%) and urea 10% cream in 9 patients (9.9%). Conclusion: There were 108 AD patients in Dermatology and Venereology Clinic, Prof. Dr. R.D. Kandou Hospital Manado from 2019-2021. Treatment with antihistamine and emollient therapy gave satisfactory results.","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":"162 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76989766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-31DOI: 10.20473/bikk.v35.2.2023.142-147
Putri Brillian, Betrista Viorizka, T. Setyaningrum, E. Qurnianingsih
Background: Melasma is a skin pigmentation disorder characterized by brownish hyperpigmented lesions with symmetrical distribution and irregular borders. It becomes a cosmetic problem that causes a negative impact on quality of life and a lack of confidence in patients. The etiology of melasma is not completely understood, but several factors that trigger melasma can be explained. Yet, the profile and triggering factors associated with the prevalence of melasma patients in Surabaya are still unexplored. Purpose: To determine the profile and triggering factors of melasma patients in the Dermatology and Venereology Outpatient Unit of Dr. Soetomo General Academic Hospital Surabaya from January to December 2019. Methods: A retrospective descriptive study using data from medical records with a total sampling technique. Result: In this study, most of the melasma patients were female (97.5%), dominated by the age group 46-55 years (49.4%), and worked as housewives (40.74%). The triggering factors found in patients were sun exposure (96.3%), cosmetics (67.9%), hormonal (49.4%), and family history (22.2%). The physical examinations of melasma lesions showed that they were mostly located in the malar area (72.8%), light brown colored (74.7%), and 2.0 – 4.0 cm in size (54.3%). Wood’s lamp examination showed that most of the lesions had firm and indistinct borders (55.6%). Conclusion: The triggering factors of melasma are multifactorial, but we suspect that sun exposure plays an important role in affecting melasma.
{"title":"The Profile and Triggering Factors of Melasma Patients: A Retrospective Study","authors":"Putri Brillian, Betrista Viorizka, T. Setyaningrum, E. Qurnianingsih","doi":"10.20473/bikk.v35.2.2023.142-147","DOIUrl":"https://doi.org/10.20473/bikk.v35.2.2023.142-147","url":null,"abstract":"Background: Melasma is a skin pigmentation disorder characterized by brownish hyperpigmented lesions with symmetrical distribution and irregular borders. It becomes a cosmetic problem that causes a negative impact on quality of life and a lack of confidence in patients. The etiology of melasma is not completely understood, but several factors that trigger melasma can be explained. Yet, the profile and triggering factors associated with the prevalence of melasma patients in Surabaya are still unexplored. Purpose: To determine the profile and triggering factors of melasma patients in the Dermatology and Venereology Outpatient Unit of Dr. Soetomo General Academic Hospital Surabaya from January to December 2019. Methods: A retrospective descriptive study using data from medical records with a total sampling technique. Result: In this study, most of the melasma patients were female (97.5%), dominated by the age group 46-55 years (49.4%), and worked as housewives (40.74%). The triggering factors found in patients were sun exposure (96.3%), cosmetics (67.9%), hormonal (49.4%), and family history (22.2%). The physical examinations of melasma lesions showed that they were mostly located in the malar area (72.8%), light brown colored (74.7%), and 2.0 – 4.0 cm in size (54.3%). Wood’s lamp examination showed that most of the lesions had firm and indistinct borders (55.6%). Conclusion: The triggering factors of melasma are multifactorial, but we suspect that sun exposure plays an important role in affecting melasma.","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84668799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-31DOI: 10.20473/bikk.v35.2.2023.158-162
Lunardi Bintanjoyo, D. Indramaya
ABSTRACT Background: Lasers are one of the most important treatment modalities in dermatology. Lasers interact with chromophores through several mechanisms that depend on fluence and pulse durations. Early lasers worked by photothermal interaction with pulse durations of 1 microsecond to 1 second. A picosecond laser is developed to confine photothermal effects and produce photomechanical effects and plasma induction. Purpose: To understand the mechanism of action and application of picosecond lasers for dermatological disorders. Review: Non-fractional picosecond lasers work by photomechanical interaction. Photomechanical interaction happens when pulse duration is less than inertial confinement time, causing fractures of chromophores with lower energy, or “cold ablation”. Fractional picosecond lasers work by laser-induced optical breakdown (LIOB). In LIOB, accelerated seed electrons cause an electron avalanche that produce a collection of free electrons called plasma, which ablates tissues. LIOB in the skin is always followed by photodisruption. In LIOB, vacuoles and debris were eliminated transdermally and dermal collagen and elastin increased. Picosecond laser may be applied in disorders requiring destruction of chromophores and for collagen and elastin disorders. It is currently the first-line treatment for tattoo removal (Nevus of Ota and Acquired Bilateral Nevus of Ota-like macules, or ABNOM). It has good efficacy and safety for solar lentigines, freckles, and cafe-au-lait macules (CALM). It is an additional treatment for moderate to severe melasma and hypertrophic scars, in combination with other treatments. The fractional picosecond laser showed moderate improvement and low risk of postinflammatory hyperpigmentation (PIH) for atrophic acne scars and produced improvement in striae alba.
{"title":"Application of Picosecond Laser in Dermatology","authors":"Lunardi Bintanjoyo, D. Indramaya","doi":"10.20473/bikk.v35.2.2023.158-162","DOIUrl":"https://doi.org/10.20473/bikk.v35.2.2023.158-162","url":null,"abstract":"ABSTRACT\u0000Background: Lasers are one of the most important treatment modalities in dermatology. Lasers interact with chromophores through several mechanisms that depend on fluence and pulse durations. Early lasers worked by photothermal interaction with pulse durations of 1 microsecond to 1 second. A picosecond laser is developed to confine photothermal effects and produce photomechanical effects and plasma induction. Purpose: To understand the mechanism of action and application of picosecond lasers for dermatological disorders. Review: Non-fractional picosecond lasers work by photomechanical interaction. Photomechanical interaction happens when pulse duration is less than inertial confinement time, causing fractures of chromophores with lower energy, or “cold ablation”. Fractional picosecond lasers work by laser-induced optical breakdown (LIOB). In LIOB, accelerated seed electrons cause an electron avalanche that produce a collection of free electrons called plasma, which ablates tissues. LIOB in the skin is always followed by photodisruption. In LIOB, vacuoles and debris were eliminated transdermally and dermal collagen and elastin increased. Picosecond laser may be applied in disorders requiring destruction of chromophores and for collagen and elastin disorders. It is currently the first-line treatment for tattoo removal (Nevus of Ota and Acquired Bilateral Nevus of Ota-like macules, or ABNOM). It has good efficacy and safety for solar lentigines, freckles, and cafe-au-lait macules (CALM). It is an additional treatment for moderate to severe melasma and hypertrophic scars, in combination with other treatments. The fractional picosecond laser showed moderate improvement and low risk of postinflammatory hyperpigmentation (PIH) for atrophic acne scars and produced improvement in striae alba.","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90906567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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