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Narrowband Ultraviolet B (NB-UVB) Phototherapy in Psoriasis: A Retrospective Study 窄带紫外线B (NB-UVB)光疗治疗银屑病的回顾性研究
Pub Date : 2022-07-31 DOI: 10.20473/bikk.v34.2.2022.99-108
Faida Ufaira Prameswari, C. Prakoeswa, Widiana Ferriastuti
Background: Psoriasis with higher Psoriasis Area and Severity Index (PASI) scores correlate with impaired quality of life. Assessing narrowband ultraviolet B (NB-UVB) phototherapy as a new therapy option in Indonesia is necessary to find the most effective treatment for psoriasis patients. Purpose: To determine the usage of NB-UVB phototherapy and the therapy response in psoriasis patients. Methods: This retrospective descriptive observational study was conducted at Dr. Soetomo General Academic Hospital Surabaya in March 2019-November 2020. The variables were collected through medical records. Result: A total of 28 patients were obtained at this study. Psoriasis type plaque/vulgaris were found in 92.9% of the patients. The patients mostly started with PASI score >10 with the initial dose of NB-UVB phototherapy is 260 mJ/cm2. The most common initial phototherapy frequency is 3 times per week (53.6%). The latest dose and frequency distribution was varied in each subject. The mean total number of sessions was 31.54 ± 20.549. Patients were also administered various combination therapy. The majority of patients had missed NB-UVB phototherapy sessions and the phototherapy dose needed to be reduced (57.1%). The achievement of PASI-75 (treatment success) was mostly achieved by subjects that went through 40-60 sessions of phototherapy and subjects with psoriasis type plaque/vulgaris. Conclusion: The achievement of PASI-75 was found to be low (17.5%), influenced by multiple factors such as the total number of NB-UVB phototherapy sessions, combination therapy, dose of NB-UVB phototherapy, frequency of NB-UVB phototherapy, and the level of patient compliance to therapy.
背景:银屑病的银屑病面积和严重程度指数(PASI)评分较高与生活质量受损相关。评估窄带紫外线B (NB-UVB)光疗在印度尼西亚作为一种新的治疗选择是必要的,以找到银屑病患者最有效的治疗方法。目的:探讨NB-UVB光疗在银屑病患者中的应用及疗效。方法:这项回顾性描述性观察性研究于2019年3月至2020年11月在泗水Soetomo综合学术医院进行。这些变量是通过医疗记录收集的。结果:本研究共获得28例患者。92.9%的患者存在银屑病型斑块/寻常型。大多数患者开始时PASI评分>10,NB-UVB光疗的初始剂量为260 mJ/cm2。最常见的初始光疗频率为每周3次(53.6%)。每个受试者的最新剂量和频率分布是不同的。平均总次数为31.54±20.549次。患者还接受了各种联合治疗。大多数患者错过了NB-UVB光疗疗程,需要减少光疗剂量(57.1%)。达到PASI-75(治疗成功)的主要是经过40-60次光疗的受试者和银屑病型斑块/寻常型受试者。结论:受NB-UVB光疗总次数、联合治疗、NB-UVB光疗剂量、NB-UVB光疗频率、患者对治疗依从性等因素的影响,PASI-75治疗成功率较低(17.5%)。
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引用次数: 0
Dermoscopic Examination in Malassezia folliculitis 马拉色菌性毛囊炎的皮肤镜检查
Pub Date : 2022-07-31 DOI: 10.20473/bikk.v34.2.2022.130-136
Zahruddin Ahmad, Evy Ervianti
Background: Malassezia folliculitis (MF) is the most common fungal folliculitis, and it is caused by yeast of the genus Malassezia. MF may be difficult to be distinguished clinically from acne and other types of folliculitis, causing misdiagnosis and improper treatment. Dermoscopy has been very useful to support the diagnosis of several types of folliculitis, including MF. Purpose: To know the role of dermoscopic examination in MF. Review: The diagnosis of MF can be identified by usual clinical presentation with direct microscopy and culture of the specimen, Wood's light examination, histopathological examination, and rapid efficacy of oral antifungal treatments. Several studies reported that dermoscopy provides a deeper level of the image that links the clinical morphology and the underlying histopathology. Some dermoscopic patterns are observed consistently with certain diseases, including MF, so these could be used for establishing their diagnosis. The dermoscopic features of MF seem to correlate with the current understanding of its etiopathogenesis. Conclusion: Dermoscopic examination in MF will reveal dermoscopic patterns including folliculocentric papule and pustules with surrounding erythema, dirty white perilesional scales, coiled/looped hairs with perifollicular erythema and scaling, hypopigmentation of involved hair follicles, and dotted vessels.
背景:马拉色菌毛囊炎(Malassezia folliculitis, MF)是最常见的真菌性毛囊炎,由马拉色菌属酵母菌引起。MF在临床上可能难以与痤疮和其他类型的毛囊炎区分,导致误诊和治疗不当。皮肤镜检查已非常有用的支持诊断几种类型的毛囊炎,包括MF。目的:了解皮肤镜检查在MF中的作用。回顾:MF的诊断可以通过常规的临床表现来确定,包括直接显微镜检查和标本培养,伍德氏光检查,组织病理学检查,以及口服抗真菌治疗的快速疗效。一些研究报道,皮肤镜检查提供了一个更深层次的图像,将临床形态学和潜在的组织病理学联系起来。一些皮肤镜观察模式与某些疾病一致,包括MF,因此这些可用于确定其诊断。MF的皮肤镜特征似乎与目前对其发病机制的理解有关。结论:MF皮镜检查可显示皮镜模式,包括毛囊中心性丘疹和脓疱周围红斑,脏白色皮损周围鳞片,卷曲/环状毛发伴毛囊周围红斑和鳞屑,受累毛囊色素减退,血管点状。
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引用次数: 1
Hand Eczema in Nurses in COVID-19 Treatment Room: Frequency of Handwashing, Hand Sanitizer, Moisturizer, and Duration of Latex Gloves Use COVID-19治疗室护士手部湿疹:洗手频率、洗手液、保湿液和乳胶手套使用时间
Pub Date : 2022-07-31 DOI: 10.20473/bikk.v34.2.2022.92-98
Ervina Rosmarwati, S. Widhiati, Dita Eka Novriana, Alfina Rahma, Harijono Kariosentono, M. Irawanto, A. Kusumawardani, Endra Yustin Ellistasari, Triasari Oktavriana
Background: The COVID-19 pandemic causes health workers to use level 2 and level 3 personal protective equipment. Hand washing and the use of latex gloves are important in limiting the spread of COVID-19, but they can potentially induce hand eczema and skin pH disturbance if used too frequently. Purpose: Determine the correlation between the frequency of handwashing and duration of using hand sanitizer and moisturizer as well as skin pH level on the incidence of hand eczema in nurses in the COVID-19 treatment room at RSUD Dr. Moewardi Surakarta. Methods: This cross-sectional study was conducted in the COVID-19 treatment room at RSUD Dr. Moewardi Surakarta with 90 nurses as subjects. A validated questionnaire carried out the frequency of handwashing, hand sanitizer, moisturizer, duration of using latex gloves, and hand eczema complaints. The subject’s pH assessment was conducted after 4-5 hours in the COVID-19 treatment room. Data were analyzed bivariately with a Spearman rank correlation test. Result: There was a significant correlation with the incidence of hand eczema with the frequency of handwashing with soap (r=0.305 and p=0.003) and the duration of using latex gloves (r=0.328 and p=0.002) with a weak category correlation (r=0.200-0.399). The frequency of using hand sanitizer, moisturizer, and skin pH did not correlate with the incidence of hand eczema. Conclusion: Frequency of handwashing and the duration of using latex gloves correlated with the incidence of hand eczema, meanwhile frequency of using hand sanitizer, using moisturizer, and skin pH didn’t correlate with the incidence of hand eczema.
背景:COVID-19大流行导致卫生工作者使用2级和3级个人防护装备。洗手和使用乳胶手套对于限制COVID-19的传播很重要,但如果使用过于频繁,它们可能会导致手部湿疹和皮肤pH值紊乱。目的:确定RSUD Dr. Moewardi Surakarta医院COVID-19治疗室护士洗手频率、使用洗手液和保湿液时间以及皮肤pH值与手部湿疹发生率的相关性。方法:本横断面研究在RSUD Dr. Moewardi Surakarta的COVID-19治疗室进行,以90名护士为研究对象。一份有效的问卷调查了洗手频率、洗手液、保湿剂、使用乳胶手套的持续时间和手部湿疹投诉。受试者在COVID-19治疗室4-5小时后进行pH值评估。采用Spearman秩相关检验对数据进行双变量分析。结果:用肥皂洗手次数(r=0.305, p=0.003)和使用乳胶手套时间(r=0.328, p=0.002)与手部湿疹发生率有显著相关性,但类别相关性较弱(r=0.200 ~ 0.399)。使用洗手液、保湿剂和皮肤pH值的频率与手部湿疹的发生率无关。结论:洗手频率、使用乳胶手套时间与手部湿疹发生率相关,使用洗手液、保湿液频率、皮肤pH值与手部湿疹发生率无相关性。
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引用次数: 0
The Relationship between Hygiene Behaviour and Acne Vulgaris Incidence in Medical Students Sebelas Maret University 西贝拉斯马雷特大学医学生卫生行为与寻常痤疮发病率的关系
Pub Date : 2022-07-31 DOI: 10.20473/bikk.v34.2.2022.125-129
Jasmine Rahmi Hapsari, Alamanda Murasmita, S. Widhiati, A. Kusumawardani
Background: Hygiene behaviour is a person’s actions in maintaining cleanliness to prevent the spread of infectious disease by cutting off the transmission of microorganisms that cause infection both in the community and in the health service. Various diseases caused by poor hygiene behaviour are diarrhea, dengue fever, leptospirosis, acute respiratory tract infections, typhoid fever, and various skin infections. One of the infectious skin diseases that affects almost the entire population is acne vulgaris. It is the highest disease prevalence worldwide and ranked 8th with 645.499.139 sufferers. Purpose: To determine the relationship between hygiene behaviour and acne vulgaris incidence in medical students at Sebelas Maret University. Methods: This study was an observational analytical study with a cross-sectional approach. This study was conducted on 45 male medical students at Sebelas Maret University. The questionnaire used was Hygiene Inventory (HI23). Data were analyzed using Fisher's Exact correlation test. Result: There is no relationship (p = 0.720) between hygiene behaviour and acne vulgaris incidence in medical students of the Sebelas Maret University. Conclusion: Hygiene behaviour has no relationship with acne vulgaris incidence in medical students at Sebelas Maret University.
背景:卫生行为是一个人保持清洁的行为,通过切断在社区和卫生服务中引起感染的微生物的传播来防止传染病的传播。不良卫生行为引起的各种疾病包括腹泻、登革热、钩端螺旋体病、急性呼吸道感染、伤寒和各种皮肤感染。寻常痤疮是影响几乎所有人群的传染性皮肤病之一。它是世界上发病率最高的疾病,以645.499.139名患者排名第八。目的:了解西贝拉斯马雷特大学医学生卫生行为与寻常性痤疮发病率的关系。方法:采用横断面方法进行观察性分析研究。本研究以45名男医学生为研究对象。问卷采用卫生量表(HI23)。采用Fisher精确相关检验对数据进行分析。结果:西贝拉斯马雷特大学医学生的卫生行为与寻常性痤疮发病率无显著相关(p = 0.720)。结论:卫生行为与西贝拉斯马雷特大学医学生寻常性痤疮发病率无关。
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引用次数: 0
Age and Nutritional Status as Factors Supporting Incidence of Atopic Dermatitis with Complications in Children: A Retrospective and Cross-Sectional Study 年龄和营养状况是支持儿童特应性皮炎并发并发症发生率的因素:一项回顾性和横断面研究
Pub Date : 2022-07-31 DOI: 10.20473/bikk.v34.2.2022.81-85
Khansa Raihani Rosmalika, D. Damayanti, A. M. Putera
Background: AD is a chronic, pruritic inflammatory skin disease that frequently occurs and common in infants and children. Purpose: This study aims to analyze the correlation of age, sex, nutritional status, and family history of atopy with the occurrence of AD complications in children. Methods: This study used a cross-sectional study design in pediatric AD patients aged 0-18 years. Data were collected from electronic medical records (EMR) of pediatric AD patients at the Dermatology Outpatient Clinic of  Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, from January to December 2019. The bivariate analysis in this study used the Chi-square test. The statistical test was significant, as indicated by p-value (p < 0.05). Result: Out of 80 eligible participants, a total of 53.75% of the participants were children aged 1-60 months, and 55% of total were female. In this study, 28.75% of participants had normal nutritional status. A total of 67.5% of patients had no family history of atopy. There was a significant relationship between age and nutritional status with the incidence of AD with complications (p=0.006 and 0.040), but no relation was found between sex and family history of atopy (p=0.444 and 0.644). Conclusion: Age and nutritional status have a correlation with the incidence of AD with complications.
背景:AD是一种常见于婴幼儿的慢性瘙痒性炎症性皮肤病。目的:本研究旨在分析儿童年龄、性别、营养状况、特应性家族史与AD并发症发生的关系。方法:本研究采用横断面研究设计,研究对象为0-18岁的儿童AD患者。数据收集自2019年1月至12月印度尼西亚泗水Dr. Soetomo综合学术医院皮肤科门诊儿科AD患者的电子病历(EMR)。本研究的双变量分析采用卡方检验。p值(p < 0.05)表示差异有统计学意义。结果:80名符合条件的参与者中,1-60月龄儿童占53.75%,女性占55%。在本研究中,28.75%的参与者营养状况正常。67.5%的患者无特应性家族史。年龄、营养状况与AD合并并发症的发生率有显著相关性(p=0.006、0.040),性别、特应性家族史与AD合并并发症发生率无显著相关性(p=0.444、0.644)。结论:年龄和营养状况与AD合并并发症的发生率相关。
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引用次数: 1
A Retrospective Study of Verruca 疣状瘤的回顾性研究
Pub Date : 2022-07-31 DOI: 10.20473/bikk.v34.2.2022.77-80
Arisia Fadila, I. Zulkarnain, M. Listiawan, A. Hidayati, S. Sawitri, D. Indramaya, Budi Utomo
Background: Verruca (non genital warts) is a quite common public health problem caused by viral infection of low risk Human Papilloma Virus (HPV) types, risking patients of all backgrounds. There is still no ideal treatment for verruca with little knowledge regarding the effectiveness of the available therapies, which results in the lack of therapeutic standard for patients. Purpose: To evaluate the incidence, management, and effectiveness of verruca treatment. Methods: This was a descriptive, retrospective study with a cross-sectional design.  All patients diagnosed with verruca in Tumor and Skin Surgery Division of the Dermatology and Venereology Outpatient Unit at Dr. Soetomo General Academic Hospital Surabaya between January 2016 and December 2020 were included in the study. Result: The results of this study obtained a total of 113 verruca patients, consisting of 61 (53.98%) male patients and 52 (46.01%) female patients, mostly aged 20-60 years old (45 patients [39.82%]). The upper extremity was the most common location where the lesion was found (39 patients [34.5%]). Electrosurgery was the most performed method (38 patients [33.6%]). Thirty-one patients who were treated and returned to the clinic at least once during the month were evaluated for the resolution of the lesion after undergoing therapy. Among 31 patients, resolution was reported in 35.5% of cases. Conclusion: Verruca is a common condition in general practice with many treatment options available yet often neglected. Knowing the available evidence for efficacy of those treatments is critical for dermatologist when considering treatment and educate patients.
背景:疣(非生殖器疣)是由低风险人乳头瘤病毒(HPV)类型的病毒感染引起的一种相当常见的公共卫生问题,所有背景的患者都有风险。目前仍没有理想的治疗方法,对现有治疗方法的有效性知之甚少,这导致患者缺乏治疗标准。目的:评价疣状瘤的发生率、处理及治疗效果。方法:采用横断面设计的描述性、回顾性研究。2016年1月至2020年12月期间,在泗水Soetomo综合学术医院皮肤科和性病门诊部肿瘤和皮肤外科诊断为疣的所有患者均被纳入研究。结果:本研究结果共获得疣体患者113例,其中男性61例(53.98%),女性52例(46.01%),年龄多为20-60岁(45例[39.82%])。上肢是最常见的病变部位(39例[34.5%])。电手术是最常用的方法(38例[33.6%])。31名接受治疗并在该月至少返回诊所一次的患者在接受治疗后评估病变的消退情况。在31例患者中,35.5%的病例报告缓解。结论:疣是一种常见的疾病,有许多治疗方法,但往往被忽视。了解这些治疗有效的现有证据对皮肤科医生在考虑治疗和教育患者时至关重要。
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引用次数: 0
Risk Factors of Syphilis and HIV/AIDS Coinfection 梅毒与HIV/AIDS合并感染的危险因素
Pub Date : 2022-07-31 DOI: 10.20473/bikk.v34.2.2022.114-119
Andre Yuindartanto, A. Hidayati, D. Indramaya, M. Listiawan, Evy Ervianti, D. Damayanti
Background: Syphilis infection and HIV are major health problems worldwide. Both of these diseases can be transmitted through sexual contact, so often a person suffers from both diseases at the same time. Purpose: To describe the risk factors of syphilis and HIV/AIDS coinfection in the Infectious Disease Intermediate Treatment Unit (UPIPI) inpatient and outpatient ward of Dr. Soetomo General Academic Hospital in 2019. Methods: The study design used in this study is a retrospective descriptive study aimed at evaluating sexual and non-sexual factors that cause syphilis and HIV coinfection. The research population was patients in the inpatient and outpatient rooms of UPIPI RSUD Dr. Soetomo Surabaya for the January-December 2019 period. The sampling technique was sourced from secondary data, namely medical record data from the inpatient and outpatient rooms of UPIPI RSUD Dr. Soetomo Surabaya for the period January-December 2019. The data in this study were obtained from medical records and patient biodata. Result: Based on the calculation results, it is known that age group (P=0.022>0.05), and gender (P=0.024>0.05) had no effect on the risk of syphilis and HIV coinfection, while marital status (P=0.048<0.05), sexual orientation (P=0.048<0.05), transmission model (P=0.044<0.05), and type of work (P=0.046<0.05fected the risk of syphilis and HIV coinfection. Conclusion: People with HIV/AIDS are expected to be active in participating in programs that are needed by patients, such as antiretroviral (ARV) therapy assistance programs and counseling that will prolong the quality of life in various aspects of life, both physical, psychological and social aspects.
背景:梅毒感染和艾滋病毒是世界范围内的主要健康问题。这两种疾病都可以通过性接触传播,所以一个人经常同时患有这两种疾病。目的:了解2019年苏托莫博士综合学术医院传染病中间治疗单元(UPIPI)住院部和门诊部梅毒和HIV/AIDS合并感染的危险因素。方法:本研究采用回顾性描述性研究,旨在评估导致梅毒和HIV合并感染的性和非性因素。研究人群为2019年1月至12月期间UPIPI RSUD Soetomo Surabaya博士住院和门诊病房的患者。抽样技术来源于二手数据,即2019年1月至12月期间UPIPI RSUD Soetomo Surabaya医生住院和门诊的病历数据。本研究的数据来源于医疗记录和患者的生物资料。结果:由计算结果可知,年龄(P=0.022>0.05)、性别(P=0.024>0.05)对梅毒和HIV合并感染的风险无影响,婚姻状况(P=0.048<0.05)、性取向(P=0.048<0.05)、传播模式(P=0.044<0.05)、工作类型(P=0.046<0.05)对梅毒和HIV合并感染的风险有影响。结论:艾滋病毒/艾滋病患者应该积极参与患者需要的项目,如抗逆转录病毒(ARV)治疗援助项目和咨询,这些项目将在生活的各个方面延长生活质量,包括身体、心理和社会方面。
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引用次数: 0
The Epidemiologic and Sociodemographic Features of Superficial Fungal Infection Among Children in East Java Suburban Public Hospital 东爪哇郊区公立医院儿童浅表真菌感染的流行病学和社会人口学特征
Pub Date : 2022-07-31 DOI: 10.20473/bikk.v34.2.2022.120-124
F. Prakoeswa, Ratih Pramuningtyas, Rully Setia Agus Dimawan
Background: Superficial fungal infection is a common skin disease among children, causing morbidity and reducing quality of life. The disease's prevalence and etiological agents change with geographic area, age, humidity, and sex. The data on this matter is still limited in Indonesia. Purpose:  To determine the current epidemiologic and sociodemographic features of superficial fungal infection among children. Methods: This descriptive study examined all the pediatric inpatients and outpatients at the Department of Dermatology and Venerology of East Java suburban Public Hospital in Indonesia from 2016 to 2020 who met the inclusion criteria. Result:  From 2016 to 2020, the number of fungal infection patients was 12.3% (n = 175) among 1,427 dermatology patients. Pityriasis versicolor (PVC) is the most common fungal skin disease (4.1%), followed by tinea capitis (2.2%), tinea cruris (1.6%), and tinea corporis (1.4%). Subjects aged 6 to 12 years old were the most likely to be infected with a fungus. Boys were more likely to develop this infection. Conclusion: From 2017 to 2020, there was a downward trend in children's superficial fungal infections. Pityriasis versicolor (PVC) is a fungal skin ailment that cause the most cases compared to other fungal infections. Boys and children between the ages of 6 to 12 years old were the most susceptible to fungal infection.
背景:浅表真菌感染是儿童常见的皮肤病,发病率高,生活质量低。该病的患病率和病因随地理区域、年龄、湿度和性别而变化。在印度尼西亚,关于这一问题的数据仍然有限。目的:了解儿童浅表真菌感染的流行病学和社会人口学特征。方法:本描述性研究对2016 - 2020年印度尼西亚东爪哇郊区公立医院皮肤性病科所有符合纳入标准的儿科住院和门诊患者进行调查。结果:2016 - 2020年,1427例皮肤科患者中真菌感染患者占12.3% (n = 175)。花斑糠疹(PVC)是最常见的真菌性皮肤病(4.1%),其次是头癣(2.2%)、股癣(1.6%)和体癣(1.4%)。6至12岁的受试者最有可能感染真菌。男孩更容易患上这种感染。结论:2017 - 2020年,儿童浅表真菌感染呈下降趋势。花斑糠疹(PVC)是一种真菌性皮肤疾病,与其他真菌感染相比,引起的病例最多。男孩和6至12岁的儿童最容易受到真菌感染。
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引用次数: 0
A Rare Case of Orbital Cellulitis with Tolosa-Hunt Syndrome Caused by Methicillin-Resistant Staphylococcus aureus (MRSA): a Case Report 耐甲氧西林金黄色葡萄球菌(MRSA)致眼眶蜂窝织炎伴Tolosa-Hunt综合征1例
Pub Date : 2022-07-31 DOI: 10.20473/bikk.v34.2.2022.137-142
Putu Evindya Vipascitadewi Nandanaya Bharata, Nyoman Suryawati, Ratih Vibriyanti Karna, P. Duarsa, Gusti Ayu Indah Triana Juliari
Background: Orbital cellulitis is an active infection of the orbital soft tissue posterior to the orbital septum, which can cause Tolosa-Hunt Syndrome (THS) complication. Purpose: We reported a child with orbital cellulitis with THS complication caused by methicillin-resistant Staphylococcus aureus (MRSA). Case: A two-year-old girl complained of swelling and pain in the left eye accompanied by fever. In nasal region and left eye showed multiple erythema patches with geographic shape, size 1x2cm - 4x5cm, unclear border, erosion with sizes 0.5x1cm - 1x1.5 cm size covered with blackish crusts. After several days of hospitalization, she complained of proptosis and pain in moving her eye. We did the magnetic resonance imaging (MRI) scan examination, which showed a mass size of 2.2 x1.1 x 0.9 cm in a left intraconal orbital and dilation of the left-sided cavernous sinus. The blood culture showed MRSA bacteria. She was diagnosed with orbital cellulitis with THS complication and showed a good response with Meropenem, Methylprednisolone, cendo lyteers eye drops, levofloxacin eye drops, and gentamicin eye ointment. Discussion: Orbital cellulitis presents as ill-defined erythema, edema, warmth, and pain around the nasal and the orbital region and is more often found in children. The THS complication is characterized by ophthalmoplegia, unilateral orbital or periorbital pain, unilateral headache, and leukocytosis. Orbital cellulitis management includes antibiotic intravenous, corticosteroid, and eye care. Conclusion: THS is a rare complication of orbital cellulitis. Early diagnosis and management of orbital cellulitis are essential to prevent THS complication.
背景:眶蜂窝织炎是一种眶隔后方眶软组织的活动性感染,可引起Tolosa-Hunt综合征(THS)并发症。目的:我们报告了一例由耐甲氧西林金黄色葡萄球菌(MRSA)引起的眼眶蜂窝织炎患儿并发三手呼吸道并发症。病例:一名两岁女童主诉左眼肿痛伴发热。鼻区及左眼多发地理形状红斑,大小为1x2cm ~ 4x5cm,边界不清,糜烂,大小为0.5x1cm ~ 1x1.5 cm,覆盖黑色结痂。住院几天后,她抱怨眼球突出,移动眼睛疼痛。我们做了磁共振成像(MRI)扫描检查,显示左侧眶内肿块大小为2.2 x1.1 x 0.9 cm,左侧海绵窦扩张。血培养显示MRSA细菌。她被诊断为眼眶蜂窝组织炎并伴有三眼综合征,并在美罗培南、甲基强的松龙、cendo lyteers滴眼液、左氧氟沙星滴眼液和庆大霉素眼膏治疗后表现良好。讨论:眼眶蜂窝织炎表现为鼻腔和眼眶周围的红斑、水肿、发热和疼痛,多见于儿童。三眼综合征的特点是眼麻痹、单侧眶或眶周疼痛、单侧头痛和白细胞增多。眼眶蜂窝织炎的治疗包括静脉注射抗生素、皮质类固醇和眼部护理。结论:眼蜂窝织炎是一种罕见的并发症。眼窝蜂窝织炎的早期诊断和处理是预防三手关节炎并发症的关键。
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引用次数: 0
Ceramide is More Effective than Shea Butter in Maintaining Skin Acidity 神经酰胺比乳木果油更能维持皮肤酸度
Pub Date : 2022-03-30 DOI: 10.20473/bikk.v34.1.2022.5-9
Zilpa Widyastuti, S. Widhiati
Background: Skin is the largest organ that functions as a physical barrier. Stable skin pH can maximize its function. Ceramide and shea butter cream have components that maintain the skin pH in the stratum corneum. Purpose: The aim is to compare ceramide and shea butter cream effects on skin pH. Methods: The experimental analytic study was performed on 30 respondents. The skin pH measurement was done before applying creams and 30 days after applying ceramide cream and shea butter cream. Ceramide cream was applied on the right volar and shea butter cream on the left volar. Comparative analysis with a paired t-test was used with a significant value of p<0.05. Results: The average skin pH after applying ceramide cream was 4,61±1,19, while shea butter cream was 5,30±1.07. The derivation of skin pH after ceramide cream application was 1,57±1,26, and that of shea butter cream was 0,88±1,14. The application of ceramide cream showed a lower pH than shea butter cream significantly, with p=0.025. Conclusion: The intervention using ceramide and shea butter cream for 30 days could lower the skin pH level. The derivation of skin pH with ceramide is more significant than using shea butter cream. Ceramide can be considered to maintain skin homeostasis and skin pH.
背景:皮肤是具有物理屏障功能的最大器官。稳定的皮肤pH值可以最大限度地发挥其功能。神经酰胺和乳木果奶油含有维持角质层皮肤pH值的成分。目的:比较神经酰胺和乳木果乳膏对皮肤ph值的影响。方法:对30名受访者进行实验分析研究。皮肤pH值测量是在涂抹面霜前和涂抹神经酰胺面霜和乳木果乳霜后30天进行的。神经酰胺乳霜涂在右掌部,乳木果油乳霜涂在左掌部。比较分析采用配对t检验,p<0.05为显著值。结果:神经酰胺乳膏涂抹后皮肤pH平均值为4.61±1.19,乳木果油乳膏涂抹后皮肤pH平均值为5.30±1.07。神经酰胺乳霜对皮肤pH值的影响为1.57±1.26,乳木果乳霜对皮肤pH值的影响为0.88±1.14。神经酰胺乳膏的pH值显著低于乳木果乳膏,p=0.025。结论:神经酰胺联合乳木果油乳膏干预30 d可降低皮肤pH值。神经酰胺对皮肤pH值的影响比乳木果油霜更显著。神经酰胺可以被认为是维持皮肤内稳态和皮肤pH值。
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Berkala Ilmu Kesehatan Kulit dan Kelamin
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