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A Split-Face Comparative Study in Efficacy and Safety between the Combination of 4% Niacinamide and 4% Kojic Acid Cream versus 4% Hydroquinone Cream for Epidermal Melasma 4%烟酰胺和4%曲酸乳膏与4%对苯二酚乳膏联合治疗表皮黄褐斑的疗效和安全性对比研究
Pub Date : 2023-07-31 DOI: 10.20473/bikk.v35.2.2023.93-99
R. Hindritiani, Felly Nazlia, Nadia Octavia, Trustia Rizqandaru, D. Puspitosari, K. Ruchiatan
Background: Melasma is a hyperpigmentation disorder that affects the quality of life, especially in women. Hydroquinone has remained the mainstay of melasma treatment. However, its safety for long-term usage became a great concern. Combination therapy, such as niacinamide and kojic acid, can be used as an alternative melasma treatment due to different mechanisms of action and synergism. Purpose: The aim of this study was to compare the efficacy and safety of a combination of 4% niacinamide and 4% kojic acid (N-K) vs. 4% hydroquinone (HQ) in epidermal melasma. Methods: This was a randomized, double blind, clinical study on 13 female epidermal melasma patients at the Cosmetic Dermatology Outpatient Clinic of Dr. Hasan Sadikin Hospital, Bandung. Patients received two creams, a combination of N-K and HQ, for split-face therapy, regardless of the sides of the face. All patients were followed up at 4 and 8 weeks. The clinical efficacy was assessed for skin lightening effects using a spectrophotometer (L* value) and the melasma area severity index (MASI). Adverse effects were assessed in all patients. Result: Both the N-K and HQ groups showed significant improvement in skin lightening and MASI scores on week 8 (p <0.05). There was no statistically significant difference in efficacy between the N-K and HQ groups (p >0.05). None of the patients in the N-K group complained of any adverse effects. Whereas in the HQ group, 23.07% presented with pruritus and mild erythema.
背景:黄褐斑是一种影响生活质量的色素沉着症,尤其是女性。对苯二酚一直是治疗黄褐斑的主要药物。然而,其长期使用的安全性成为人们非常关注的问题。烟酰胺和曲酸联合治疗由于其作用机制和协同作用不同,可作为黄褐斑的替代治疗方法。目的:本研究的目的是比较4%烟酰胺和4%曲酸(N-K)与4%对苯二酚(HQ)联合治疗表皮黄褐斑的疗效和安全性。方法:这是一项随机、双盲的临床研究,研究对象是万隆哈桑·萨迪金医生医院美容皮肤科门诊的13名女性表皮黄褐斑患者。患者接受两种面霜,N-K和HQ的组合,用于面部分裂治疗,无论面部的两侧如何。所有患者均于第4周和第8周随访。采用分光光度计(L*值)和黄褐斑面积严重指数(MASI)评估临床疗效。对所有患者的不良反应进行评估。结果:N-K组和HQ组在第8周皮肤亮度和MASI评分均有显著改善(p < 0.05)。N-K组中没有患者抱怨有任何不良反应。而HQ组23.07%出现瘙痒和轻度红斑。
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引用次数: 0
Impacts of Clinical and Demographical Aspects on the Duration of Pytiriasis Versicolor 临床及人口学因素对花斑黄疸病程的影响
Pub Date : 2023-07-31 DOI: 10.20473/bikk.v35.2.2023.107-115
M. K. Khamdan, Yuri Widia, R. Setiabudi, Evy Ervianti
Background: Pityriasis versicolor (PV) or tinea versicolor is a superficial fungal infection characterized by macules on the skin. It is generally caused by the fungus Malassezia. PV is found throughout the world, especially in tropical countries. Generally, this infection is influenced by humidity, hyperhidrosis, and population density around the world. One of the ways to establish PV is through the KOH examination. Purpose: Evaluating the correlation between the clinical and demographic factors and the duration of illness of outpatient PV patients of the Mycology Division of Dermatology and Venereology Department at Dr. Soetomo General Academic Hospital from 2018 to 2020. Methods: This is an observational analytic study based on medical records at the outpatient clinic of Mycology Division of the Dermatology and Venereology Department of Dr. Soetomo General Academic Hospital. The data was collected in October 2021. The chi-square test is used to analyze the data in this study. Result: 216 PV patients’ data was collected. Most gender was male, most age group was 20-60, most weight group was 51 – 60 kg, most regional origin was from Surabaya, and most duration of infection was <3 months. In this study, topical and systemic treatment of this disease had a significant relationship with patients’ duration of illness (topical p=0.05; systemic p=0.026). Conclusion:  Topical and systemic treatment of this disease has a significant relationship with the duration of illness in PV patients.
背景:花斑癣(PV)或花斑癣是一种以皮肤上的斑点为特征的浅表真菌感染。它通常是由真菌马拉色菌引起的。光伏发电遍布世界各地,特别是在热带国家。一般来说,这种感染受湿度、多汗症和世界各地人口密度的影响。建立PV的方法之一是通过KOH检查。目的:评价2018 - 2020年苏托莫博士综合学术医院皮肤性病科真菌学科门诊PV患者的临床及人口学因素与病程的相关性。方法:这是一项基于Dr. Soetomo综合学术医院皮肤性病科真菌学科门诊病历的观察性分析研究。该数据于2021年10月收集。本研究数据采用卡方检验进行分析。结果:共收集到216例PV患者资料。性别多为男性,年龄多为20 ~ 60岁,体重多为51 ~ 60 kg,地域多为泗水地区,感染时间多为<3个月。在本研究中,局部和全身治疗与患者病程有显著关系(局部p=0.05;系统性p = 0.026)。结论:局部和全身治疗与PV患者的病程有显著关系。
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引用次数: 0
Clinical Profile of Contact Dermatitis Patients at the Allergy-Immunology Division of Dermatology and Venereology Outpatient Clinic 皮肤性病科门诊变态反应免疫科接触性皮炎患者临床概况
Pub Date : 2023-07-31 DOI: 10.20473/bikk.v35.2.2023.100-106
Gabriel Rio Widipriyatama, L. Dewanti, Sylvia Anggraeni, Damayanti
Background: Contact dermatitis is an inflammatory skin response that can be caused by several things. This inflammatory reaction is most often caused by external compounds that become allergens or irritants to the body. Purpose: To evaluate the clinical profile of contact dermatitis patients at the allergy-immunology division of dermatology and venereology outpatient clinic of Dr. Soetomo general academic hospital. Methods: The sampling technique used in this study is a total sampling technique and was processed with Excel descriptively. Result: The most frequent age group diagnosed with contact dermatitis was the 20–45-year-old age group (45.5%). The most frequent gender was female (72.2%). The most frequent occupation was private employee (30.8%). The most frequent suspected causal factor was cosmetics (35.2%). Itching was the most common type of patient complaint (44.1%). Face was the most frequent location (30.8%). Erythematous macules were the most frequent clinical manifestation (45.9%). The diagnosis of contact dermatitis was divided into allergic contact dermatitis ACD (60.4%) and irritant contact dermatitis ICD (39.6%). The most frequent topical therapy was corticosteroid (53.2%). Meanwhile, the most systemic therapy is antihistamine (73.8%). Conclusion: ACD is more prevalent than ICD and is more prevalent in women between the ages of 20 and 45. The most prevalent occupation distribution is among private employees. Cosmetics are the most frequently suspected cause factor. Itch is the most common patient complaint. The face is where contact dermatitis occurs most frequently. Erythematous macules are the most frequent clinical symptom. Corticosteroids and antihistamines are the most commonly given medication.
背景:接触性皮炎是一种皮肤炎症反应,可由多种原因引起。这种炎症反应通常是由外部化合物引起的,这些化合物会成为身体的过敏原或刺激物。目的:了解苏托莫综合医院皮肤科性病科变态反应免疫科门诊接触性皮炎患者的临床情况。方法:本研究采用的抽样技术为全抽样技术,并采用Excel进行描述性处理。结果:接触性皮炎以20 ~ 45岁年龄组最常见(45.5%)。最常见的性别是女性(72.2%)。最常见的职业是私营企业雇员(30.8%)。最常见的疑似原因是化妆品(35.2%)。瘙痒是患者最常见的主诉(44.1%)。面部是最常见的部位(30.8%)。红斑斑是最常见的临床表现(45.9%)。接触性皮炎的诊断分为过敏性接触性皮炎ACD(60.4%)和刺激性接触性皮炎ICD(39.6%)。最常见的外用治疗是皮质类固醇(53.2%)。与此同时,最常见的是抗组胺药(73.8%)。结论:ACD患病率高于ICD,且多见于20 ~ 45岁的女性。最普遍的职业分布是私营部门雇员。化妆品是最常被怀疑的原因。瘙痒是患者最常见的主诉。面部是接触性皮炎最常发生的部位。红斑是最常见的临床症状。皮质类固醇和抗组胺药是最常用的药物。
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引用次数: 0
Review Article: Skin Condition and Skin Care in Premature Infants 综述文章:早产儿的皮肤状况和皮肤护理
Pub Date : 2023-03-31 DOI: 10.20473/bikk.v35.1.2023.67-73
Yuri Widia, B. Rosdiana
Background: The majority of newborn skin care recommendations focus on concerns for healthy, full-term infants. Compared to mature infants, the skin of premature infants, those who are born at the gestational age of 37 weeks, is more vulnerable to injury, transepidermal water loss (TEWL), and transepidermal intoxication. There are no established guidelines for premature infant skin care. Discussion and review regarding this topic are needed. Purpose: To review the literature on skin conditions and skin care in premature infants. Review: The barrier function of premature skin is significantly compromised because the stratum corneum does not fully mature until late in the third trimester. Premature infants have immature skin with impaired barrier function characterized by high TEWL, increased absorption of chemicals, and increased risk of infection. Some particular issues in premature infant skin are controlling TEWL, avoiding mechanical damage, proper sterilization to control infection, awareness of percutaneous drug toxicity, appropriate bathing and umbilical cord care, and appropriate management of skin problems. Conclusion: Premature infant skin is more vulnerable due to immature development. Skin care for premature infants requires careful attention.
背景:大多数新生儿皮肤护理建议关注健康的足月婴儿。与成熟婴儿相比,37周出生的早产儿的皮肤更容易受到损伤、经皮失水(TEWL)和经皮中毒。对于早产儿的皮肤护理尚无既定的指导方针。需要对这一主题进行讨论和回顾。目的:回顾有关早产儿皮肤状况和皮肤护理的文献。回顾:由于角质层直到妊娠晚期才完全成熟,早产儿皮肤的屏障功能明显受损。早产儿皮肤发育不成熟,屏障功能受损,其特征是TEWL高,化学物质吸收增加,感染风险增加。早产儿皮肤的一些特殊问题是控制水分流失,避免机械损伤,适当的消毒以控制感染,意识到经皮药物毒性,适当的沐浴和脐带护理,以及适当的皮肤问题管理。结论:早产儿皮肤发育不成熟,易受伤害。早产儿的皮肤护理需要特别注意。
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引用次数: 0
Chemical Peeling in Skin-Aging Patients: A Retrospective Study 皮肤老化患者的化学脱皮:一项回顾性研究
Pub Date : 2023-03-31 DOI: 10.20473/bikk.v35.1.2023.6-14
Ester Chateline Susanto, T. Setyaningrum, Arifa Mustika, L. Astari
Background: Skin aging is a degenerative process that involves a decrease in the structure and function of skin cells and theextracellular matrix due to intrinsic and extrinsic factors. Chemical peeling is one of the skin aging treatments that involvesskin ablation using chemical agents. Purpose: To evaluate the profile of skin-aging patients treated with chemical peeling atthe Dermatology and Venereology Outpatient Unit of Dr. Soetomo General Hospital Surabaya from January throughDecember 2019. Methods: The data were obtained from patients’ medical records through a total sampling technique, whichconsisted of age, gender, occupation, history taking, physical examination, diagnosis, therapeutic agents, follow-up frequency,and therapeutic result. Result: The study included 37 patients, the majority of whom were between the ages of 46 and 55(35.1%), female (100%), and private employees (32.4%). In history taking, patients’ main complaint is dull skin (94.6%), withthe risk factor of sun exposure (97.3%) and the history of sunscreen usage (81.1%). Pigmentary changes were found in allpatients (100%). The most common diagnoses are photoaging Glogau II and Glogau III, found in 15 patients (40.5%),respectively. The common priming agents were sunscreen (97.3%), cleanser (94.6%), and 8% glycolic acid (75.7%). Themajority of patients (62.2%) received 20% glycolic acid as a peeling agent and sunscreen (86.5%) as a post-peeling agent.The majority of patients (43.2%) did not follow up. Glogau II photoaging (57.1%) was the main therapeutic result.Conclusion: Proper chemical peeling procedures and patients compliance are important factors to improve therapeuticoutcomes.
背景:皮肤老化是一种退化过程,涉及皮肤细胞和细胞外基质的结构和功能由于内在和外在因素的减少。化学脱皮是一种使用化学试剂消融皮肤的皮肤老化治疗方法。目的:评估2019年1月至12月在泗水Soetomo综合医院皮肤科和性病门诊接受化学脱皮治疗的皮肤老化患者的情况。方法:采用全抽样的方法,收集患者的病历资料,包括年龄、性别、职业、病史、体格检查、诊断情况、治疗药物、随访次数、治疗效果等。结果:共纳入37例患者,年龄在46 ~ 55岁之间的占35.1%,女性占100%,私营企业从业人员占32.4%。在病史调查中,患者的主要主诉为皮肤暗沉(94.6%),危险因素为日晒(97.3%)和防晒霜使用史(81.1%)。所有患者均有色素改变(100%)。最常见的诊断是光老化Glogau II和Glogau III,分别在15例患者中发现(40.5%)。常见的引妆剂是防晒霜(97.3%)、洗面奶(94.6%)和8%的乙醇酸(75.7%)。大多数患者(62.2%)使用20%乙醇酸作为脱皮剂,并使用防晒霜(86.5%)作为脱皮后剂。大多数患者(43.2%)没有随访。Glogau II光老化为主要治疗结果(57.1%)。结论:正确的化学脱皮方法和患者的依从性是改善治疗效果的重要因素。
{"title":"Chemical Peeling in Skin-Aging Patients: A Retrospective Study","authors":"Ester Chateline Susanto, T. Setyaningrum, Arifa Mustika, L. Astari","doi":"10.20473/bikk.v35.1.2023.6-14","DOIUrl":"https://doi.org/10.20473/bikk.v35.1.2023.6-14","url":null,"abstract":"Background: Skin aging is a degenerative process that involves a decrease in the structure and function of skin cells and theextracellular matrix due to intrinsic and extrinsic factors. Chemical peeling is one of the skin aging treatments that involvesskin ablation using chemical agents. Purpose: To evaluate the profile of skin-aging patients treated with chemical peeling atthe Dermatology and Venereology Outpatient Unit of Dr. Soetomo General Hospital Surabaya from January throughDecember 2019. Methods: The data were obtained from patients’ medical records through a total sampling technique, whichconsisted of age, gender, occupation, history taking, physical examination, diagnosis, therapeutic agents, follow-up frequency,and therapeutic result. Result: The study included 37 patients, the majority of whom were between the ages of 46 and 55(35.1%), female (100%), and private employees (32.4%). In history taking, patients’ main complaint is dull skin (94.6%), withthe risk factor of sun exposure (97.3%) and the history of sunscreen usage (81.1%). Pigmentary changes were found in allpatients (100%). The most common diagnoses are photoaging Glogau II and Glogau III, found in 15 patients (40.5%),respectively. The common priming agents were sunscreen (97.3%), cleanser (94.6%), and 8% glycolic acid (75.7%). Themajority of patients (62.2%) received 20% glycolic acid as a peeling agent and sunscreen (86.5%) as a post-peeling agent.The majority of patients (43.2%) did not follow up. Glogau II photoaging (57.1%) was the main therapeutic result.Conclusion: Proper chemical peeling procedures and patients compliance are important factors to improve therapeuticoutcomes.","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81350236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Pattern of Pediatric Parasitic Skin Diseases in a Secondary Hospital in East Java: A Retrospective Study 东爪哇一家二级医院儿童寄生虫皮肤病的模式:回顾性研究
Pub Date : 2023-03-31 DOI: 10.20473/bikk.v35.1.2023.52-56
F. Prakoeswa, Ratih Pramuningtyas, Rully Setia Agus Dimawan
Background: Epidermal parasitic skin diseases (EPSDs) are a group of neglected infectious diseases caused by parasites that infect the upper layer of the skin. A parasitic infection of the skin is caused by small insects or worms that burrow into the skin to live there or lay their eggs. EPSDs are a public health issue and can occur in children of all ages. Purpose: This study aims to describe the pattern and incidences of parasitic skin infections in children. Methods: This is a cross-sectional study utilizing medical records from the Dermatology and Venereology Clinic of Dr. Harjono Ponorogo General Public Hospital from 2016 to 2020. Result: Our study showed that, of the 1426 children brought to our clinic, parasitic infection was the second most common skin disease found in children with a prevalence of 27.1%. Parasitic infection in children was dominated by males with a proportion of 69.7%, and occurred mostly in the ≥13-year-old age group. Among all ages, scabies is the most frequent parasitic infection found, followed by cutaneous larva migrant (CLM) and pediculosis. Conclusion: The prevalence of EPSDs is increasing with age and is more common in males. This high prevalence is probably due to increased intensity of contact with other people, decreased parental care, and low socio-economic status.
背景:表皮寄生性皮肤病(EPSDs)是由寄生在皮肤上层的寄生虫引起的一组被忽视的传染病。皮肤的寄生虫感染是由小昆虫或蠕虫引起的,它们钻进皮肤,在那里生活或产卵。epsd是一个公共卫生问题,可发生在所有年龄段的儿童中。目的:本研究旨在描述儿童皮肤寄生虫感染的模式和发病率。方法:本研究是一项横断面研究,利用Dr. Harjono Ponorogo综合公立医院皮肤科和性病诊所2016年至2020年的医疗记录。结果:我们的研究表明,在我们门诊就诊的1426名儿童中,寄生虫感染是儿童皮肤疾病中第二常见的疾病,患病率为27.1%。儿童寄生虫感染以男性为主,占69.7%,多发生在≥13岁年龄组。在所有年龄段中,疥疮是最常见的寄生虫感染,其次是皮肤幼虫迁移(CLM)和弓根病。结论:epsd患病率随年龄增长而增加,以男性多见。这种高流行率可能是由于与其他人接触的强度增加、父母照料减少以及社会经济地位低下所致。
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引用次数: 0
Occupational Contact Dermatitis Risk Factors on Healthcare Workers Isolation Ward During the COVID-19 Pandemic COVID-19大流行期间医护人员隔离病房职业性接触性皮炎危险因素分析
Pub Date : 2023-03-31 DOI: 10.20473/bikk.v35.1.2023.27-39
Andre Yuindartanto, Sawitri, Astindari, Cita Rosita Sigit Prakoeswa, Damayanti, Sylvia Anggraen, M. Umborowati, I. Zulkarnain, M. Listiawan, A. Hidayati
Background: After a history of exposure to the suspected material and a thorough physical examination, the diagnosis of occupational contact dermatitis (OCD) is commonly suspected. During the initial consultation, essential information involving the above is frequently neglected. Purpose: To evaluate the clinical manifestations of OCD cases in health workers and analyze the factors that influence OCD cases in health workers at the isolation ward of Dr. Soetomo Surabaya Hospital during the COVID-19 pandemic. Methods: The sample selection was done through purposive sampling. Accessible population that met the inclusion criteria and did not have exclusion criteria were included as research samples. The target population was healthcare workers in the Special Isolation Ward of Dr. Soetomo Hospital Surabaya. The accessible population was healthcare workers who performed hand hygiene activities and used Personal Protective Equipment (PPE) in the Special Isolation Ward of Dr. Soetomo Hospital Surabaya. The research subjects were healthcare workers who worked in the Special Isolation Ward. Result: The research results showed a strong and significant correlation between atopic history and the occurrence of contact dermatitis due to poor skin barrier function and decreased tolerance. The study also found that there was no significant correlation between atopic history and the severity level of OCD. There was a significant difference in transepidermal water loss (TEWL) values in the lesion and non-lesion areas, both on the palmar and dorsal aspects of the hand. Moisturizer is an important component in managing hand dermatitis as it can repair and maintain the skin's protective barrier. Conclusion:
背景:职业性接触性皮炎(OCD)的诊断常被怀疑为职业性接触性皮炎(OCD)。在最初的协商中,涉及上述的重要信息往往被忽视。目的:了解新冠肺炎大流行期间泗水苏莫医生医院隔离病房医护人员强迫症的临床表现,分析影响医护人员强迫症发病的因素。方法:采用目的抽样法进行样本选择。将符合纳入标准且没有排除标准的无障碍人群作为研究样本。目标人群是泗水Soetomo医生医院特别隔离病房的医护人员。可接触的人群是在泗水Soetomo医生医院特别隔离病房进行手部卫生活动并使用个人防护装备的卫生保健工作者。研究对象为在特殊隔离病房工作的医护人员。结果:研究结果显示,由于皮肤屏障功能差,耐受性降低,特应性病史与接触性皮炎的发生有很强且显著的相关性。研究还发现,特应性病史与强迫症的严重程度之间没有明显的相关性。在手掌和手背的病变区和非病变区,经皮失水(TEWL)值有显著差异。润肤霜是处理手部皮炎的重要成分,因为它可以修复和维持皮肤的保护屏障。结论:
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引用次数: 0
Henoch-Schonlein Purpura in Adult with Gastrointestinal and Renal Involvement 累及胃肠道和肾脏的成人过敏性紫癜
Pub Date : 2023-03-31 DOI: 10.20473/bikk.v35.1.2023.74-80
Aprilin Krista Devi, M. Umborowati, Sylvia Anggraeni, D. Damayanti, C. Prakoeswa
Background: The pathogenesis of Henoch-Schonlein Purpura (HSP), a multisystem organ-involved small vessel vasculitis, is unknown. HSP is more common in youngsters than in adults. HSP is associated with a history of malignancies, medications, vaccinations, and upper respiratory tract infections. Painful purpura, arthritis, stomach discomfort, and renal involvement are symptoms that may be seen in HSP patients. Adult patients had a much higher rate of renal involvement than children. Purpose: To report a case of HSP in an adult with gastrointestinal and renal involvement. Case: A 45-year-old man complained of an arm, leg, and waist rash for two weeks before admission to the hospital. He also has stomach pains, nausea, and vomiting to deal with. His symptoms have just appeared now for the first time. During a renal function test, blood urea nitrogen (BUN) and creatine serum levels rose. On a urinalysis, proteinuria and microscopic hematuria were found. Leucocytoclastic vasculitis was discovered during the histopathology investigation. HSP diagnosis was based on the ACR and ICC criteria. The patient was given 3x2 tablets of 0.5 mg dexamethasone, 3x2 tablets of cetirizine, 2x10 mg lisinopril, 2x50 mg ranitidine injection, and 2 grams ceftriaxone. Discussion: The clinical symptoms of HSP are used to make the diagnosis. In the vast majority of instances, the treatment is only supportive therapy. Corticosteroid usually are usually used for HSP with multisystem organ involvement to reduce pain severity and faster resolution of renal manifestation. Conclusion: Follow up on renal function is needed to monitor the worsening of renal disease.
背景:过敏性紫癜(HSP)是一种累及多系统器官的小血管炎,其发病机制尚不清楚。热休克在青少年中比在成人中更常见。HSP与恶性肿瘤史、药物史、疫苗史和上呼吸道感染史有关。疼痛性紫癜、关节炎、胃部不适和肾脏受累是HSP患者可能出现的症状。成人患者的肾脏受累率远高于儿童。目的:报告一例成人HSP伴胃肠道和肾脏受累。病例:一名45岁男性,入院前两周主诉手臂、腿部和腰部出现皮疹。他还有胃痛、恶心和呕吐等症状。他的症状现在才第一次出现。肾功能检查时,血尿素氮(BUN)和血清肌酸水平升高。尿检发现蛋白尿和显微镜下血尿。组织病理学检查发现白细胞分裂性血管炎。HSP的诊断基于ACR和ICC标准。患者给予地塞米松0.5 mg 3x2片,西替利嗪3x2片,赖诺普利2x10 mg,雷尼替丁注射液2x50 mg,头孢曲松2g。讨论:利用热休克的临床症状进行诊断。在绝大多数情况下,治疗只是支持性治疗。皮质类固醇通常用于多系统器官受累的HSP,以减轻疼痛严重程度和更快地解决肾脏表现。结论:监测肾脏疾病的恶化需要对肾功能进行随访。
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引用次数: 0
Profile of Skin Tumors at Dr. Zainoel Abidin General Hospital Dermatology and Venerology Outpatient Clinic in 2017 – 2021 : A Retrospective Study 2017 - 2021年Zainoel Abidin医生总医院皮肤性病门诊皮肤肿瘤概况:一项回顾性研究
Pub Date : 2023-03-31 DOI: 10.20473/bikk.v35.1.2023.40-45
Wahyu Lestari, Nanda Earlia Fitria, Sitti Hajar, Mimi Maulida
Background: Skin tumors are swellings caused by proliferation or failure of cell death mechanisms. Based on the type of growth, skin tumors are divided into benign tumors and malignant tumors. Purpose: To investigate the incidence of skin tumors in Dr. Zainoel Abidin General Hospital outpatient clinic. Methods: This study is a descriptive study with  total sampling. The diagnosis of skin tumors is assessed based on medical records filled by Dr. Zainoel Abidin General Hospital Dermatovenerologist in January 2017-September 2021. Result: The results showed patients diagnosed with benign skin tumors had as many as 360 subjects and malignant tumors had as many as 4 samples. The majority of women are affected by benign and malignant skin tumors. Based on the age of benign tumors dominated by the age of 22-45 years while in malignant tumors dominated by 45-64 years.  The majority of the sample comes from Banda Aceh, based on where the most of them reside. Based on the size of lesions, benign tumors are dominated by lesions that are less than 0.5 cm in size, while malignant tumors are dominated by lesions that are larger than 0.5 cm in size. Based on the presence and absence of recursion the entire dominant sample has no recursion. Based on the physical treatment in benign tumors are dominated by electrocautery action while malignant tumors are the same number between general surgery and FNAB. Conclusion: most of the skin tumors found in Dr. Zainoel Abidin General Hospital dermatology and venerology outpatient clinic are benign
背景:皮肤肿瘤是由细胞增殖或细胞死亡机制失败引起的肿胀。根据生长类型,皮肤肿瘤分为良性肿瘤和恶性肿瘤。目的:调查阿比丁总医院门诊皮肤肿瘤的发病率。方法:采用全抽样方法进行描述性研究。根据Zainoel Abidin综合医院皮肤性病专家2017年1月至2021年9月填写的医疗记录评估皮肤肿瘤的诊断。结果:确诊为良性皮肤肿瘤的患者多达360例,确诊为恶性肿瘤的患者多达4例。大多数女性受到良性和恶性皮肤肿瘤的影响。根据年龄,良性肿瘤以22-45岁为主,恶性肿瘤以45-64岁为主。根据大多数人居住的地方,大多数样本来自班达亚齐。从病变大小来看,良性肿瘤以小于0.5 cm的病变为主,恶性肿瘤以大于0.5 cm的病变为主。基于递归的存在和不存在,整个优势样本没有递归。在物理治疗的基础上,良性肿瘤以电灼作用为主,恶性肿瘤以普通外科手术与FNAB手术数量相当。结论:在Zainoel Abidin总医院皮肤科和性病科门诊发现的皮肤肿瘤多数为良性
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引用次数: 0
Characteristics and Clinical Profile of Vitiligo Patients in Dermatology and Venereology Outpatient Clinic Unit at Dr. Soetomo General Academic Hospital Surabaya 泗水Soetomo博士综合学术医院皮肤科和性病门诊部白癜风患者的特点和临床概况
Pub Date : 2023-03-31 DOI: 10.20473/bikk.v35.1.2023.1-5
Alvian Arifin Saiboo, Cita Rosita Sigit Prakoeswa, D. Indramaya, A. Hidayati, Damayanti, Rahmadewi, B. Utomo, Frizka Eliza
Background: Vitiligo is a depigmentation disorder characterized by the progressive loss of melanocytes from the epidermis and hair follicles. Vitiligo affects all age groups and is defined by acquired, idiopathic, progressive, different-sized, circumscribed, milky white depigmentation. Characteristics and clinical patterns of vitiligo will also help to understand the pathogenesis of the disease. Purpose: The aim of this study is to evaluate the characteristics profile and clinical features of vitiligo patients. Methods: The research material was taken from the medical record of vitiligo patients in the Division of Cosmetics Outpatient Clinic Dermatovenerelogy Dr. Soetomo General Hospital Surabaya from 2018-2020. Result: This study was obtained by a number of new vitiligo patients 115 (0.3%) of the total number of new outpatient clinic visits of Dermatovenereology Dr. Soetomo General Hospital Surabaya. The majority of the gender is female (53.9%), late adolescence (26.96%), students (25.22%), and the onset of vitiligo 1-5 years (30.43%). The most common risk factors were idiopathic (51.3%) and clinical types are non-segmental vitiligo (53.04%). Conclusion: Vitiligo predominantly affects in females with active age groups of 17-25 years old, and students.
背景:白癜风是一种以表皮和毛囊黑色素细胞逐渐丧失为特征的色素脱失性疾病。白癜风影响所有年龄组,定义为获得性,特发性,进行性,不同大小,有边界的乳白色色素沉着。白癜风的特点和临床模式也将有助于了解疾病的发病机制。目的:探讨白癜风患者的临床特征及特点。方法:研究资料取自泗水Soetomo总医院化妆品门诊皮肤性病科2018-2020年白癜风患者的病历。结果:本研究获得了一些新的白癜风患者115(0.3%)的新门诊门诊就诊皮肤科性病博士苏托莫综合医院泗水。以女性(53.9%)居多,青春期晚期(26.96%)、学生(25.22%)居多,发病时间为1-5年(30.43%)。最常见的危险因素为特发性(51.3%),临床类型为非节段性白癜风(53.04%)。结论:白癜风主要发生在17-25岁活跃年龄组的女性和学生中。
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引用次数: 0
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Berkala Ilmu Kesehatan Kulit dan Kelamin
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