Pub Date : 2022-11-30DOI: 10.20473/bikk.v34.3.2022.169-173
Ervina Rosmarwati, N. Mulianto, Bobby Febrianto, Dita Eka Novriana, Siti Efrida Fiqnasyani
Background: Psoriasis Vulgaris is an autoimmune disease characterized by chronic skin inflammation and epidermal hyperplasia. Psoriasis Area Severity Index (PASI) score is one of the assessments to measure the psoriasis severity. Oral methotrexate is one of the effective therapies for psoriasis patients. Narrow Band-Ultraviolet B (NB-UVB) phototherapy is an adjunctive psoriasis therapy given concurrently with oral methotrexate. Purpose: Determine the difference in Psoriasis Area Severity Index (PASI) scores between Psoriasis Vulgaris patients treated with oral methotrexate and a combination of oral methotrexate and NB-UVB phototherapy. Methods: This observational analytic study was conducted at the Dermatology and Venereology Clinic, Dr. Moewardi General Hospital Surakarta. The patients received oral methotrexate and a combination of oral methotrexate and and Narrow Band-Ultraviolet B (NB-UVB) phototherapy. A retrospective study of medical records was conducted to determine the patient's PASI score before the therapies and 3 months after. All data were analyzed with the Shapiro Wilk normality test and the independent T-test. A p-value was <0.05, and it was considered significant. Result: The mean of decreased PASI scores in the oral methotrexate group was (6.00 +2.47) and (6.08 +2.17) in the combination therapy group. Based on the statistical test results from the 24 subjects, it was found that the PASI score decreased (p=0.931). Conclusion: There was no significant difference in the decrease in PASI between the oral methotrexate group and the combination therapy group. The mean reduction of PASI scores was more significant in the combination therapy than in the methotrexate group
背景:寻常型牛皮癣是一种以慢性皮肤炎症和表皮增生为特征的自身免疫性疾病。银屑病严重程度指数(Psoriasis Area Severity Index, PASI)评分是衡量银屑病严重程度的指标之一。口服甲氨蝶呤是治疗银屑病的有效方法之一。窄带紫外线B (NB-UVB)光疗是一种辅助治疗银屑病同时给予口服甲氨蝶呤。目的:确定口服甲氨蝶呤与口服甲氨蝶呤联合NB-UVB光疗对寻常型银屑病患者银屑病区严重指数(PASI)评分的差异。方法:这项观察性分析研究在雅加达Moewardi综合医院皮肤病和性病诊所进行。患者接受口服甲氨蝶呤和口服甲氨蝶呤与窄带紫外线B (NB-UVB)光疗联合治疗。对医疗记录进行回顾性研究，以确定患者在治疗前和治疗后3个月的PASI评分。所有数据均采用Shapiro Wilk正态性检验和独立t检验进行分析。p值<0.05，认为显著。结果:口服甲氨蝶呤组PASI评分下降的平均值为(6.00 +2.47)，联合治疗组PASI评分下降的平均值为(6.08 +2.17)。根据24名被试的统计检验结果，PASI得分下降(p=0.931)。结论:口服甲氨蝶呤组与联合治疗组在PASI降低方面无显著差异。与甲氨蝶呤组相比，联合治疗组PASI评分的平均降低更为显著
{"title":"Comparison of Psoriasis Area and Severity Index (PASI) Scores in Patients Treated with Oral Methotrexate and A Combination of Oral Methotrexate and Narrow Band-Ultraviolet B (NB-UVB) Phototherapy","authors":"Ervina Rosmarwati, N. Mulianto, Bobby Febrianto, Dita Eka Novriana, Siti Efrida Fiqnasyani","doi":"10.20473/bikk.v34.3.2022.169-173","DOIUrl":"https://doi.org/10.20473/bikk.v34.3.2022.169-173","url":null,"abstract":"Background: Psoriasis Vulgaris is an autoimmune disease characterized by chronic skin inflammation and epidermal hyperplasia. Psoriasis Area Severity Index (PASI) score is one of the assessments to measure the psoriasis severity. Oral methotrexate is one of the effective therapies for psoriasis patients. Narrow Band-Ultraviolet B (NB-UVB) phototherapy is an adjunctive psoriasis therapy given concurrently with oral methotrexate. Purpose: Determine the difference in Psoriasis Area Severity Index (PASI) scores between Psoriasis Vulgaris patients treated with oral methotrexate and a combination of oral methotrexate and NB-UVB phototherapy. Methods: This observational analytic study was conducted at the Dermatology and Venereology Clinic, Dr. Moewardi General Hospital Surakarta. The patients received oral methotrexate and a combination of oral methotrexate and and Narrow Band-Ultraviolet B (NB-UVB) phototherapy. A retrospective study of medical records was conducted to determine the patient's PASI score before the therapies and 3 months after. All data were analyzed with the Shapiro Wilk normality test and the independent T-test. A p-value was <0.05, and it was considered significant. Result: The mean of decreased PASI scores in the oral methotrexate group was (6.00 +2.47) and (6.08 +2.17) in the combination therapy group. Based on the statistical test results from the 24 subjects, it was found that the PASI score decreased (p=0.931). Conclusion: There was no significant difference in the decrease in PASI between the oral methotrexate group and the combination therapy group. The mean reduction of PASI scores was more significant in the combination therapy than in the methotrexate group","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":"245 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74494883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-11-30DOI: 10.20473/bikk.v34.3.2022.203-209
Made Putri Hendaria, Maylita Sari
Background: Physiological changes in a woman's life, such as labor, weight fluctuations, hormonal changes, aging, and menopause, cause changes in both appearance and function of the vagina. As estrogen deficiency continues, changes occur in the form of atrophy and dystrophy in the vaginal mucosa, vulva, and other structures in the urogenital tract which are called symptoms of vulvovaginal atrophy. It affects women's quality of life, self-confidence, and sexuality. As alternative modality for noninvasive therapy, topical therapy in vaginal rejuvenation is becoming available in the care of outpatients. This makes it increasingly important for dermatologists to be well-informed about these treatment options. Purpose: This review aims to assess the role of topical therapy in vaginal rejuvenation, especially in vulvovaginal atrophy cases. Literature Review: Vulvovaginal atrophy has a negative effect on interpersonal relationships, quality of life, daily activities, and sexual function. Topical hormone replacement therapy includes all preparations such as estradiol, estradiol valerate, or conjugated estrogen. considered in cases with vulvovaginal atrophy accompanied by atrophy of the urogenital system as well as the accompanying complaints because this therapy is intended to prevent systemic complications. The topical use of hyaluronic acid, lubricants, moisturizers, and herbs is a therapeutic choice in vulvovaginal atrophy patients contraindicated with estrogen therapy or in patients who do indeed choose nonhormonal therapy. Conclusion: Topical therapy of hormonal and non-hormonal rejuvenation in various studies has shown improvement in symptoms of vaginal dryness, vaginal itching, dyspareunia, cell maturity, and changes in vaginal pH toward acidity.
{"title":"The Role of Topical Treatment on Vaginal Tightening","authors":"Made Putri Hendaria, Maylita Sari","doi":"10.20473/bikk.v34.3.2022.203-209","DOIUrl":"https://doi.org/10.20473/bikk.v34.3.2022.203-209","url":null,"abstract":"Background: Physiological changes in a woman's life, such as labor, weight fluctuations, hormonal changes, aging, and menopause, cause changes in both appearance and function of the vagina. As estrogen deficiency continues, changes occur in the form of atrophy and dystrophy in the vaginal mucosa, vulva, and other structures in the urogenital tract which are called symptoms of vulvovaginal atrophy. It affects women's quality of life, self-confidence, and sexuality. As alternative modality for noninvasive therapy, topical therapy in vaginal rejuvenation is becoming available in the care of outpatients. This makes it increasingly important for dermatologists to be well-informed about these treatment options. Purpose: This review aims to assess the role of topical therapy in vaginal rejuvenation, especially in vulvovaginal atrophy cases. Literature Review: Vulvovaginal atrophy has a negative effect on interpersonal relationships, quality of life, daily activities, and sexual function. Topical hormone replacement therapy includes all preparations such as estradiol, estradiol valerate, or conjugated estrogen. considered in cases with vulvovaginal atrophy accompanied by atrophy of the urogenital system as well as the accompanying complaints because this therapy is intended to prevent systemic complications. The topical use of hyaluronic acid, lubricants, moisturizers, and herbs is a therapeutic choice in vulvovaginal atrophy patients contraindicated with estrogen therapy or in patients who do indeed choose nonhormonal therapy. Conclusion: Topical therapy of hormonal and non-hormonal rejuvenation in various studies has shown improvement in symptoms of vaginal dryness, vaginal itching, dyspareunia, cell maturity, and changes in vaginal pH toward acidity.","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81979474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-11-30DOI: 10.20473/bikk.v34.3.2022.217-222
Armyta Denissafitri, Riezky Januar Pramitha, Yuri Widia, I. Citrashanty, I. Zulkarnain, S. Sawitri
Background: Infantile hemangioma (IH) is the most common benign tumor in infancy. Most IHs resolve spontaneously and do not require treatment. Therapeutic intervention is necessary for life-threatening IH, tumors posing functional risks, ulceration, and severe anatomic distortion, especially on the face. Beta-blockers, most specifically propranolol, have been shown to induce involution of IH, which should be administered as early as possible to avoid potential complications. Purpose: To report a case of IH with visual impairment treated successfully using oral propranolol. Case: A 4-month-old girl weighing, 6.3 kg, with redness plaques on the right face since 3 weeks after birth. The lesions rapidly increased in size within 2 months, and the lesions on her right eyelid made it difficult to open her right eye. Dermatological examination showed erythematous plaques, compressible and varying in size and ptosis. The patient was diagnosed with periocular infantile hemangioma and was given oral propranolol therapy with an initiated dose 3x1 mg. The dose was increased gradually. The lesions were significantly decreased and she could open her right eye normally after 5 months of propranolol therapy. Discussion: Some cases of IH require early treatment. Early treatment is indicated for IH causing functional impairment. The use of propranolol in the management of IH is very effective in the reduction of the lesions and Has minimal side effects. Conclusion: Early diagnosis and intervention with propranolol for IH play an important role in determining the optimal outcomes.
{"title":"Excellent Response of Infantile Hemangioma with Oral Propranolol: A Case Report","authors":"Armyta Denissafitri, Riezky Januar Pramitha, Yuri Widia, I. Citrashanty, I. Zulkarnain, S. Sawitri","doi":"10.20473/bikk.v34.3.2022.217-222","DOIUrl":"https://doi.org/10.20473/bikk.v34.3.2022.217-222","url":null,"abstract":"Background: Infantile hemangioma (IH) is the most common benign tumor in infancy. Most IHs resolve spontaneously and do not require treatment. Therapeutic intervention is necessary for life-threatening IH, tumors posing functional risks, ulceration, and severe anatomic distortion, especially on the face. Beta-blockers, most specifically propranolol, have been shown to induce involution of IH, which should be administered as early as possible to avoid potential complications. Purpose: To report a case of IH with visual impairment treated successfully using oral propranolol. Case: A 4-month-old girl weighing, 6.3 kg, with redness plaques on the right face since 3 weeks after birth. The lesions rapidly increased in size within 2 months, and the lesions on her right eyelid made it difficult to open her right eye. Dermatological examination showed erythematous plaques, compressible and varying in size and ptosis. The patient was diagnosed with periocular infantile hemangioma and was given oral propranolol therapy with an initiated dose 3x1 mg. The dose was increased gradually. The lesions were significantly decreased and she could open her right eye normally after 5 months of propranolol therapy. Discussion: Some cases of IH require early treatment. Early treatment is indicated for IH causing functional impairment. The use of propranolol in the management of IH is very effective in the reduction of the lesions and Has minimal side effects. Conclusion: Early diagnosis and intervention with propranolol for IH play an important role in determining the optimal outcomes.","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":"422 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78119195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-11-30DOI: 10.20473/bikk.v34.3.2022.184-188
Rully Setia Agus Dimawan, F. Prakoeswa, Ratih Pramuningtyas
Background: Viral and bacterial skin infection is a common condition amongst children. In developing countries, it is a complex major health problem. However, epidemiological study on viral and bacterial skin infection in the pediatric population is still lacking, especially in Indonesia. Purpose: This study aimed to evaluate bacterial and viral skin infection amongst children and its association with age and sex. Methods: This study used a cross-sectional design with a retrospective approach. We retrieved medical records of pediatric patients admitted to Dr. Harjono S Ponorogo General Public Hospital between 2016 and 2020. Result: Of the 1,427 collected medical records, we found that the viral infection prevalence was 4.9% (n=70) and 7.5% (n= 107) for bacterial skin infection. Viral infection was most observed amongst subjects in the >12-year age group and 2–12-year for bacterial infection. Infection was more commonly observed amongst boys. Conclusion: The skin infection prevalence in Dr. Harjono S. Ponorogo General Hospital is lower compared to other studies. Skin infection of viral origin was most reported in children aged >12 years and bacterial infection in children aged 2–12. Both skin infections were more commonly observed in boys than girls.
背景:病毒性和细菌性皮肤感染是儿童的常见病。在发展中国家，这是一个复杂的重大健康问题。然而，儿童人群中病毒和细菌皮肤感染的流行病学研究仍然缺乏，特别是在印度尼西亚。目的:本研究旨在评估儿童皮肤细菌和病毒感染及其与年龄和性别的关系。方法:本研究采用回顾性的横断面设计。我们检索了2016年至2020年在Dr. Harjono S Ponorogo General Public Hospital住院的儿科患者的医疗记录。结果:1427份病历中，病毒感染发生率为4.9% (n=70)，细菌性皮肤感染发生率为7.5% (n= 107)。病毒感染在>12岁年龄组中最多，细菌感染在2- 12岁年龄组中最多。感染在男孩中更为常见。结论:哈约诺综合医院皮肤感染患病率较低。病毒性皮肤感染多见于12岁以上儿童，细菌性皮肤感染多见于2-12岁儿童。这两种皮肤感染在男孩中比女孩更常见。
{"title":"Pediatric Viral and Bacterial Skin Infection Profile","authors":"Rully Setia Agus Dimawan, F. Prakoeswa, Ratih Pramuningtyas","doi":"10.20473/bikk.v34.3.2022.184-188","DOIUrl":"https://doi.org/10.20473/bikk.v34.3.2022.184-188","url":null,"abstract":"Background: Viral and bacterial skin infection is a common condition amongst children. In developing countries, it is a complex major health problem. However, epidemiological study on viral and bacterial skin infection in the pediatric population is still lacking, especially in Indonesia. Purpose: This study aimed to evaluate bacterial and viral skin infection amongst children and its association with age and sex. Methods: This study used a cross-sectional design with a retrospective approach. We retrieved medical records of pediatric patients admitted to Dr. Harjono S Ponorogo General Public Hospital between 2016 and 2020. Result: Of the 1,427 collected medical records, we found that the viral infection prevalence was 4.9% (n=70) and 7.5% (n= 107) for bacterial skin infection. Viral infection was most observed amongst subjects in the >12-year age group and 2–12-year for bacterial infection. Infection was more commonly observed amongst boys. Conclusion: The skin infection prevalence in Dr. Harjono S. Ponorogo General Hospital is lower compared to other studies. Skin infection of viral origin was most reported in children aged >12 years and bacterial infection in children aged 2–12. Both skin infections were more commonly observed in boys than girls.","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73663561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-11-30DOI: 10.20473/bikk.v34.3.2022.210-216
Nevristia Pratama, Luh Made Mas Rusyati, Prima Sanjiwani Saraswati Sudarsa, IGAA Dwi Karmila, NLP Ratih Vibriyanti Karna
Background: Leprosy is a chronic granulomatous infectious disease caused by Mycobacterium leprae (M. leprae) that primarily infects Schwann cells in the peripheral nerves, leading to nerve damage and the development of disabilities. In 2018, Indonesia was the third country with the most leprosy cases in the world. Erythema nodosum leprosum (ENL), also known as type II leprosy reaction, is a severe immune-mediated complication of multibacillary leprosy. Purpose: To report a case of borderline lepromatous leprosy with severe ENL. Case: A 49-year-old Balinese man presented with multiple tender erythematous skin nodules all over his body, fever, arthralgia, bilateral cervical lymphadenopathy, and sensory loss for the past week. The acid-fast bacilli bacteriological examination showed a positive result. The patient was diagnosed with borderline lepromatous (BL) leprosy with severe ENL and was treated with multibacillary multidrug therapy (MB MDT), methylprednisolone, and other symptomatic medications. After 1 month of treatment, there was an improvement in skin lesions. The MB-MDT treatment was continued and methylprednisolone was planned to be tapered down gradually. Discussion: Approximately 20-50% of all leprosy patients show leprosy reactions in the course of the disease. The goals of treatment for severe ENL are to control inflammation, reduce pain, treat neuritis to prevent nerve dysfunction and contractures, and prevent recurring ENL. The prognosis of leprosy with ENL reactions depends on the severity of the occurring leprosy reaction; early diagnosis and prompt treatment; and patient compliance with treatment. Conclusion: Early diagnosis and treatment are essential to avoid deformities in leprosy patients.
{"title":"Borderline Lepromatous Leprosy with Severe Erythema Nodosum Leprosum: A Case Report","authors":"Nevristia Pratama, Luh Made Mas Rusyati, Prima Sanjiwani Saraswati Sudarsa, IGAA Dwi Karmila, NLP Ratih Vibriyanti Karna","doi":"10.20473/bikk.v34.3.2022.210-216","DOIUrl":"https://doi.org/10.20473/bikk.v34.3.2022.210-216","url":null,"abstract":"Background: Leprosy is a chronic granulomatous infectious disease caused by Mycobacterium leprae (M. leprae) that primarily infects Schwann cells in the peripheral nerves, leading to nerve damage and the development of disabilities. In 2018, Indonesia was the third country with the most leprosy cases in the world. Erythema nodosum leprosum (ENL), also known as type II leprosy reaction, is a severe immune-mediated complication of multibacillary leprosy. Purpose: To report a case of borderline lepromatous leprosy with severe ENL. Case: A 49-year-old Balinese man presented with multiple tender erythematous skin nodules all over his body, fever, arthralgia, bilateral cervical lymphadenopathy, and sensory loss for the past week. The acid-fast bacilli bacteriological examination showed a positive result. The patient was diagnosed with borderline lepromatous (BL) leprosy with severe ENL and was treated with multibacillary multidrug therapy (MB MDT), methylprednisolone, and other symptomatic medications. After 1 month of treatment, there was an improvement in skin lesions. The MB-MDT treatment was continued and methylprednisolone was planned to be tapered down gradually. Discussion: Approximately 20-50% of all leprosy patients show leprosy reactions in the course of the disease. The goals of treatment for severe ENL are to control inflammation, reduce pain, treat neuritis to prevent nerve dysfunction and contractures, and prevent recurring ENL. The prognosis of leprosy with ENL reactions depends on the severity of the occurring leprosy reaction; early diagnosis and prompt treatment; and patient compliance with treatment. Conclusion: Early diagnosis and treatment are essential to avoid deformities in leprosy patients.","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":"64 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74832354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-11-30DOI: 10.20473/bikk.v34.3.2022.149-155
Maylita Sari, Lunardi Bintanjoyo, B. H. Kusumaputra, I. Citrashanty, A. Hidayati, Dwi Murtiastutik, M. Listiawan, C. Prakoeswa
Background: In 2007, skin cancers were third most common malignancies in Indonesia. However, profile of cutaneous tumors in our institution has not been studied. Purpose: To evaluate profile of cutaneous tumors in Dermatology and Venerology Outpatient Clinic, Dr. Soetomo General Hospital, Surabaya, Indonesia. Methods: This is a descriptive retrospective study. Inclusion criteria was new cutaneous tumor patients. Exclusion criteria was incomplete data. Medical record and photograph database from 2019-2020 were assessed for demography, clinical features, histopathological examination and final diagnosis. Results: There were 379 (5,5%) cutaneous tumors among 6896 new patients at Dermatology and Venereology Outpatient Clinic. Overall, there were more female patients (53.7%) and age group of 0-45 years old (70.4%). Cutaneous tumors more commonly presented as papular (50.4%), multiple (56.5%), nonpigmented (58.3%), asymptomatic lesions (62.5%), with time from onset 0-24 months (66.2%) and location on head and face (61.2%). Benign cutaneous tumors showed similar findings. Malignant cutaneous tumors showed differences including predominantly male sex, age above 45 years old, nodular, solitary, pigmented and easily bleeding lesions. Malignant tumors were less common (6.9%). Most common malignant tumor was BCC. Most common benign and overall cutaneous tumor was seborrheic keratosis. Conclusion: Cutaneous tumors presented across gender and ages, showing heterogenous clinical manifestations. Malignant and benign cutaneous tumors showed similarity on time from onset and location of lesions. However, differences were seen in demographic profiles and majority of clinical features. BCC was the most common malignant cutaneous tumors, while seborrheic keratosis was the most common benign and overall cutaneous tumors.
{"title":"A Retrospective Study of Demographic, Clinical, and Histopathological Profiles of Cutaneous Tumors","authors":"Maylita Sari, Lunardi Bintanjoyo, B. H. Kusumaputra, I. Citrashanty, A. Hidayati, Dwi Murtiastutik, M. Listiawan, C. Prakoeswa","doi":"10.20473/bikk.v34.3.2022.149-155","DOIUrl":"https://doi.org/10.20473/bikk.v34.3.2022.149-155","url":null,"abstract":"Background: In 2007, skin cancers were third most common malignancies in Indonesia. However, profile of cutaneous tumors in our institution has not been studied. Purpose: To evaluate profile of cutaneous tumors in Dermatology and Venerology Outpatient Clinic, Dr. Soetomo General Hospital, Surabaya, Indonesia. Methods: This is a descriptive retrospective study. Inclusion criteria was new cutaneous tumor patients. Exclusion criteria was incomplete data. Medical record and photograph database from 2019-2020 were assessed for demography, clinical features, histopathological examination and final diagnosis. Results: There were 379 (5,5%) cutaneous tumors among 6896 new patients at Dermatology and Venereology Outpatient Clinic. Overall, there were more female patients (53.7%) and age group of 0-45 years old (70.4%). Cutaneous tumors more commonly presented as papular (50.4%), multiple (56.5%), nonpigmented (58.3%), asymptomatic lesions (62.5%), with time from onset 0-24 months (66.2%) and location on head and face (61.2%). Benign cutaneous tumors showed similar findings. Malignant cutaneous tumors showed differences including predominantly male sex, age above 45 years old, nodular, solitary, pigmented and easily bleeding lesions. Malignant tumors were less common (6.9%). Most common malignant tumor was BCC. Most common benign and overall cutaneous tumor was seborrheic keratosis. Conclusion: Cutaneous tumors presented across gender and ages, showing heterogenous clinical manifestations. Malignant and benign cutaneous tumors showed similarity on time from onset and location of lesions. However, differences were seen in demographic profiles and majority of clinical features. BCC was the most common malignant cutaneous tumors, while seborrheic keratosis was the most common benign and overall cutaneous tumors.","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":"95 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78297561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-11-30DOI: 10.20473/bikk.v34.3.2022.189-196
Nopriyati Nopriyati, Cayadi Sidarta Antonius, H. M. A. Thaha, S. Diba, Y. Kurniawati, F. Argentina
Background: A skin prick test is one method to detect allergies. Skin prick testing in dermatology can be performed on atopic dermatitis and urticaria. Skin prick test can be done easily, it’s relatively safe, fast, and can use many allergens simultaneously in one test. Purpose: To describe the characteristics of the skin prick test results at the clinic of Dermatology and Venereology, Mohammad Hoesin Palembang General Hospital, for the period 2016-2021. Methods: Descriptive retrospective study using a cross-sectional approach. Medical record data for the period January 2016-December 2021. Result: The number of patients who underwent skin prick testing during the period January 2016 to December 2021 was 116 patients, dominated by women (59.5%) and those aged 26-35 years (40.5%). The majority of diagnoses examined were atopic dermatitis (48.3%) and chronic urticaria (31.9%). The most positive results were for allergens in the form of house dust mites, shrimp, and crabs. The positive proportion of milkfish allergen was higher in women, while the positive proportion of shrimp allergen was higher in men. Chicken feather allergen showed significant differences between the diagnoses of atopic dermatitis, chronic urticaria and acute urticaria. Conclusion: House dust mites were the dominant allergen in patients with atopic dermatitis, chronic urticaria, and acute urticaria. skin prick test is recommended to be performed in the management of atopic dermatitis, chronic urticaria, and acute urticaria in order to detect the allergen because it has significant clinical relevance.
{"title":"Skin Prick Test Profile: A Retrospective Study","authors":"Nopriyati Nopriyati, Cayadi Sidarta Antonius, H. M. A. Thaha, S. Diba, Y. Kurniawati, F. Argentina","doi":"10.20473/bikk.v34.3.2022.189-196","DOIUrl":"https://doi.org/10.20473/bikk.v34.3.2022.189-196","url":null,"abstract":"Background: A skin prick test is one method to detect allergies. Skin prick testing in dermatology can be performed on atopic dermatitis and urticaria. Skin prick test can be done easily, it’s relatively safe, fast, and can use many allergens simultaneously in one test. Purpose: To describe the characteristics of the skin prick test results at the clinic of Dermatology and Venereology, Mohammad Hoesin Palembang General Hospital, for the period 2016-2021. Methods: Descriptive retrospective study using a cross-sectional approach. Medical record data for the period January 2016-December 2021. Result: The number of patients who underwent skin prick testing during the period January 2016 to December 2021 was 116 patients, dominated by women (59.5%) and those aged 26-35 years (40.5%). The majority of diagnoses examined were atopic dermatitis (48.3%) and chronic urticaria (31.9%). The most positive results were for allergens in the form of house dust mites, shrimp, and crabs. The positive proportion of milkfish allergen was higher in women, while the positive proportion of shrimp allergen was higher in men. Chicken feather allergen showed significant differences between the diagnoses of atopic dermatitis, chronic urticaria and acute urticaria. Conclusion: House dust mites were the dominant allergen in patients with atopic dermatitis, chronic urticaria, and acute urticaria. skin prick test is recommended to be performed in the management of atopic dermatitis, chronic urticaria, and acute urticaria in order to detect the allergen because it has significant clinical relevance.","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90926375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-31DOI: 10.20473/bikk.v34.2.2022.86-91
Farah Ayu Noviannisa, L. Astari, Lindawati Alimsardjono
Background: Tinea capitis (TC) is a superficial mycoses infection of hair follicles and hair shaft caused by dermatophytes of the genus Trichophyton and Microsporum. Tinea capitis can cause hair loss and scales with varying degrees of inflammatory response. The incidence varies depending on geographical location and factors that affect the incidence rate. It is important to know the incidence also the clinical and cure profile of tinea capitis to provide benefits in the prevention, diagnosis, and treatment. Purpose: To evaluate the clinical and cure profile of TC patients at the Dermatology and Venereology Outpatient Clinic of Dr. Soetomo General Academic Hospital Surabaya from January 2019 to January 2020. Methods: A retrospective descriptive study based on medical records with a total sampling technique. Result: Of the 10 TC patients, who were the research subjects, TC predominantly affected males and at 5–11 years age group. The highest risk factor was a history of contact with cats. Scales were the most common clinical feature. Microsporum canis was the most common causative species, ectothrix arthrospores was revealed during the direct microscopic examination, Wood lamp's fluorescence was mostly yellow-green, and cigarette-shaped hair was the most common dermoscopic finding. Eighty percent of subjects were diagnosed with gray patch type. Conclusion: The diagnosis of TC was established based on the patient's history, clinical examination, and supporting examination.
{"title":"Clinical and Cure Profile of Tinea Capitis Patients","authors":"Farah Ayu Noviannisa, L. Astari, Lindawati Alimsardjono","doi":"10.20473/bikk.v34.2.2022.86-91","DOIUrl":"https://doi.org/10.20473/bikk.v34.2.2022.86-91","url":null,"abstract":"Background: Tinea capitis (TC) is a superficial mycoses infection of hair follicles and hair shaft caused by dermatophytes of the genus Trichophyton and Microsporum. Tinea capitis can cause hair loss and scales with varying degrees of inflammatory response. The incidence varies depending on geographical location and factors that affect the incidence rate. It is important to know the incidence also the clinical and cure profile of tinea capitis to provide benefits in the prevention, diagnosis, and treatment. Purpose: To evaluate the clinical and cure profile of TC patients at the Dermatology and Venereology Outpatient Clinic of Dr. Soetomo General Academic Hospital Surabaya from January 2019 to January 2020. Methods: A retrospective descriptive study based on medical records with a total sampling technique. Result: Of the 10 TC patients, who were the research subjects, TC predominantly affected males and at 5–11 years age group. The highest risk factor was a history of contact with cats. Scales were the most common clinical feature. Microsporum canis was the most common causative species, ectothrix arthrospores was revealed during the direct microscopic examination, Wood lamp's fluorescence was mostly yellow-green, and cigarette-shaped hair was the most common dermoscopic finding. Eighty percent of subjects were diagnosed with gray patch type. Conclusion: The diagnosis of TC was established based on the patient's history, clinical examination, and supporting examination.","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88646363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-31DOI: 10.20473/bikk.v34.2.2022.143-148
Anindia Indraswari, M. Listiawan
Background: Leprosy is a chronic infectious disease caused by Mycobacterium leprae. Cases of leprosy in children are rarely found because of the long incubation period of Mycobacterium leprae. Purpose: To report a case of mid-borderline leprosy with a mild type 1 reaction in a seven-years-old girl patient. Case: A 7-years-old girl patient presented with multiple red and white patches on her face, body, arms, legs, and buttocks since 6 months before. There was no itching, numbness, painr fever. There was no thickening of peripheral nerves and no nerve function impairment. Her grandmother was suspected to have leprosy, but she had never been treated and had already passed away. From the acid fast bacilli (AFB) examination, the bacterial index (BI) was 1+ and the morphological index (MI) was 2%. A serologic test examination was also performed and the result were Immunoglobulin (Ig) G 3716 u/ml and IgG 284 u/ml. The patient got multidrugs therapy for 12 months and after 9 months of treatment, the pre-existing patches became erythematous, thickened, and felt pain when touched, but there was no fever. In the presence of pain, oral ibuprofen was then administered and the patches began to improveDiscussion: Due to the possibility of leprosy reaction, it is important to immediately give prompt treatment to children with type 1 leprosy reaction that is associated with neuritis and leads to deformities. Conclusion: Early diagnosis and therapy for a type 1 leprosy reaction are very important to prevent deformities.
{"title":"Mid-Borderline Leprosy with Mild Type 1 Reaction in Children: A Case Report","authors":"Anindia Indraswari, M. Listiawan","doi":"10.20473/bikk.v34.2.2022.143-148","DOIUrl":"https://doi.org/10.20473/bikk.v34.2.2022.143-148","url":null,"abstract":"Background: Leprosy is a chronic infectious disease caused by Mycobacterium leprae. Cases of leprosy in children are rarely found because of the long incubation period of Mycobacterium leprae. Purpose: To report a case of mid-borderline leprosy with a mild type 1 reaction in a seven-years-old girl patient. Case: A 7-years-old girl patient presented with multiple red and white patches on her face, body, arms, legs, and buttocks since 6 months before. There was no itching, numbness, painr fever. There was no thickening of peripheral nerves and no nerve function impairment. Her grandmother was suspected to have leprosy, but she had never been treated and had already passed away. From the acid fast bacilli (AFB) examination, the bacterial index (BI) was 1+ and the morphological index (MI) was 2%. A serologic test examination was also performed and the result were Immunoglobulin (Ig) G 3716 u/ml and IgG 284 u/ml. The patient got multidrugs therapy for 12 months and after 9 months of treatment, the pre-existing patches became erythematous, thickened, and felt pain when touched, but there was no fever. In the presence of pain, oral ibuprofen was then administered and the patches began to improveDiscussion: Due to the possibility of leprosy reaction, it is important to immediately give prompt treatment to children with type 1 leprosy reaction that is associated with neuritis and leads to deformities. Conclusion: Early diagnosis and therapy for a type 1 leprosy reaction are very important to prevent deformities.","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84663751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-31DOI: 10.20473/bikk.v34.2.2022.109-113
Silvani Geani, R. Rahmadewi, A. Astindari, C. Prakoeswa, S. Sawitri, Evy Ervianti, B. Utomo, M. Listiawan
Background: Leprosy is a chronic granulomatous infectious disease caused by Mycobacterium leprae that affects peripheral nerves and skin. The interaction between M. leprae and Schwann cells causes irreversible damage to peripheral nervous tissue afterward disability occurs. Involvement of the major nervous trunks of the extremities can produce sensory-motor deficits. The risk factors are delay in diagnosis, gender, age, type of leprosy, duration of disease, number of affected nerves, leprosy reaction, type of treatment, socioeconomic factors, education, ethnicity, and occupation. Purpose: The aim was to study the profile of leprosy patients with disability who seek treatment in Leprosy Division Dermatovenerology Outpatient Clinic RSUD Dr. Soetomo Surabaya. Methods: This was a descriptive retrospective study of leprosy patients with disability from January 2017 to December 2019. Result: The results of this study obtained a total of 275 leprosy patients with disabilities, which consisted of 76 patients (27.6%) with grade-1 disability and 199 patients (72.4%) with grade-2 disability. The majority were male (73.4%) and aged 25-44 years old (42.2%). Other dominant risk factors were MB type leprosy (92%), duration of disease more than 12 months (52.3%), no leprosy reaction (68%), and had received multidrug therapy (45.5%). Conclusion: Knowledge of disability risk factors can assist in improving management and education to prevent disability in leprosy patients.
{"title":"Profile of Disability in Leprosy Patients: A Retrospective Study","authors":"Silvani Geani, R. Rahmadewi, A. Astindari, C. Prakoeswa, S. Sawitri, Evy Ervianti, B. Utomo, M. Listiawan","doi":"10.20473/bikk.v34.2.2022.109-113","DOIUrl":"https://doi.org/10.20473/bikk.v34.2.2022.109-113","url":null,"abstract":"Background: Leprosy is a chronic granulomatous infectious disease caused by Mycobacterium leprae that affects peripheral nerves and skin. The interaction between M. leprae and Schwann cells causes irreversible damage to peripheral nervous tissue afterward disability occurs. Involvement of the major nervous trunks of the extremities can produce sensory-motor deficits. The risk factors are delay in diagnosis, gender, age, type of leprosy, duration of disease, number of affected nerves, leprosy reaction, type of treatment, socioeconomic factors, education, ethnicity, and occupation. Purpose: The aim was to study the profile of leprosy patients with disability who seek treatment in Leprosy Division Dermatovenerology Outpatient Clinic RSUD Dr. Soetomo Surabaya. Methods: This was a descriptive retrospective study of leprosy patients with disability from January 2017 to December 2019. Result: The results of this study obtained a total of 275 leprosy patients with disabilities, which consisted of 76 patients (27.6%) with grade-1 disability and 199 patients (72.4%) with grade-2 disability. The majority were male (73.4%) and aged 25-44 years old (42.2%). Other dominant risk factors were MB type leprosy (92%), duration of disease more than 12 months (52.3%), no leprosy reaction (68%), and had received multidrug therapy (45.5%). Conclusion: Knowledge of disability risk factors can assist in improving management and education to prevent disability in leprosy patients.","PeriodicalId":8792,"journal":{"name":"Berkala Ilmu Kesehatan Kulit dan Kelamin","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88243253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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