Pub Date : 2019-12-31DOI: 10.11129/9783955534998-015
{"title":"Serpentine Gallery Pavilion London, GB","authors":"","doi":"10.11129/9783955534998-015","DOIUrl":"https://doi.org/10.11129/9783955534998-015","url":null,"abstract":"","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87785747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-31DOI: 10.11129/9783955534998-fm
{"title":"Frontmatter","authors":"","doi":"10.11129/9783955534998-fm","DOIUrl":"https://doi.org/10.11129/9783955534998-fm","url":null,"abstract":"","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86665757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-31DOI: 10.11129/9783955534998-001
{"title":"Blox Kopenhagen / Copenhagen, DK","authors":"","doi":"10.11129/9783955534998-001","DOIUrl":"https://doi.org/10.11129/9783955534998-001","url":null,"abstract":"","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79485963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-31DOI: 10.11129/9783955534998-017
{"title":"Prada Epicenter New York City, US","authors":"","doi":"10.11129/9783955534998-017","DOIUrl":"https://doi.org/10.11129/9783955534998-017","url":null,"abstract":"","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89848461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-12-31DOI: 10.11129/9783955534998-009
{"title":"De Rotterdam Rotterdam, NL","authors":"","doi":"10.11129/9783955534998-009","DOIUrl":"https://doi.org/10.11129/9783955534998-009","url":null,"abstract":"","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83901119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Neves, P. Patra, Qiwei Li, A. Magazzù, M. Käll, G. Volpe
Water near an optically trapped particle absorbs part of the laser energy resulting in changes for the refractive index and density. Particle position and optical potential description are affected by this photothermal effect.
{"title":"Beam Displacement due to Thermal Blooming in Optical Tweezers","authors":"A. Neves, P. Patra, Qiwei Li, A. Magazzù, M. Käll, G. Volpe","doi":"10.1364/oma.2019.aw4e.3","DOIUrl":"https://doi.org/10.1364/oma.2019.aw4e.3","url":null,"abstract":"Water near an optically trapped particle absorbs part of the laser energy resulting in changes for the refractive index and density. Particle position and optical potential description are affected by this photothermal effect.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87655100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-04-15DOI: 10.1364/boda.2019.jt4a.17
R. Draham, Kaitlin J. Dunn, A. Berger
We constructed a microscope system that obtains angular scattering information using dark-field quantitative phase imaging. In this technique, unscattered light acts as a reference for interferometry. We tested the system using polystyrene beads.
{"title":"Dark-field quantitative phase imaging for angular scattering","authors":"R. Draham, Kaitlin J. Dunn, A. Berger","doi":"10.1364/boda.2019.jt4a.17","DOIUrl":"https://doi.org/10.1364/boda.2019.jt4a.17","url":null,"abstract":"We constructed a microscope system that obtains angular scattering information using dark-field quantitative phase imaging. In this technique, unscattered light acts as a reference for interferometry. We tested the system using polystyrene beads.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86528781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Weizhen Li, Revanth Kailashnath, Yang Qian, J. Marsh, Alasdair WClark, S. Neale
Optoelectronic tweezers (OET) offers a flexible method to manipulate and assemble solder beads into desired patterns. Using an ultraviolet curable solution as a buffer, the assembled microstructures can be immobilized on the device.
{"title":"Manipulate and Immobilize Microparticles by Optoelectronic Tweezers and Ultraviolet Curing","authors":"Weizhen Li, Revanth Kailashnath, Yang Qian, J. Marsh, Alasdair WClark, S. Neale","doi":"10.1364/OMA.2019.AW4E.4","DOIUrl":"https://doi.org/10.1364/OMA.2019.AW4E.4","url":null,"abstract":"Optoelectronic tweezers (OET) offers a flexible method to manipulate and assemble solder beads into desired patterns. Using an ultraviolet curable solution as a buffer, the assembled microstructures can be immobilized on the device.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89455953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Fränzl, T. Thalheim, J. Adler, D. Huster, F. Cichos
The aggregation of proteins into amyloid fibrils is fundamental for the understanding of neurodegenerative disorders. Here, we demonstrate a method for the investigation of growth and breakup of single Aβ40 amyloid fibrils in a thermophoretic trap.
{"title":"Single Amyloid Fibrils Studied in a Thermophoretic Trap","authors":"M. Fränzl, T. Thalheim, J. Adler, D. Huster, F. Cichos","doi":"10.1364/oma.2019.am2e.3","DOIUrl":"https://doi.org/10.1364/oma.2019.am2e.3","url":null,"abstract":"The aggregation of proteins into amyloid fibrils is fundamental for the understanding of neurodegenerative disorders. Here, we demonstrate a method for the investigation of growth and breakup of single Aβ40 amyloid fibrils in a thermophoretic trap.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78097592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Tinnefeld, G. Acuna, Qingshan Wei, A. Ozcan, Carolin Vietz, B. Lalkens, Kateryna Trofymchuk, Cindy Close, Hakan Inan, Sarah E. Ochmann, Lennart Grabenhorst, Viktorija Glembockyte
In recent years, DNA nanotechnology has matured to enable robust production of complex nanostructures and hybrid materials. We have combined DNA nanotechnology with sensitive optical detection to create functional single-molecule devices that enable new applications in single-molecule biosensing and superresolution microscopy. Starting with superresolution nanorulers and brightness reference samples we determined the resolving power of superresolution microscopes and evaluated the sensitivity of smartphone cameras. To improve the sensitivity we created DNA origami optical antennas for metal enhanced fluorescence. The unique ability of our DNA origami nanoantennas to place molecular assays specifically in the plasmonic hotspot is used for detecting Zika-virus nucleic acids. The fluorescence enhancement is further exploited to achieve ultra-sensitive detection on low-cost devices such as a modified smartphone leading to the democratization of single-molecule detection.
{"title":"DNA origami nanotools for single-molecule biosensing and superresolution microscopy","authors":"P. Tinnefeld, G. Acuna, Qingshan Wei, A. Ozcan, Carolin Vietz, B. Lalkens, Kateryna Trofymchuk, Cindy Close, Hakan Inan, Sarah E. Ochmann, Lennart Grabenhorst, Viktorija Glembockyte","doi":"10.1364/oma.2019.aw5e.5","DOIUrl":"https://doi.org/10.1364/oma.2019.aw5e.5","url":null,"abstract":"In recent years, DNA nanotechnology has matured to enable robust production of complex nanostructures and hybrid materials. We have combined DNA nanotechnology with sensitive optical detection to create functional single-molecule devices that enable new applications in single-molecule biosensing and superresolution microscopy. Starting with superresolution nanorulers and brightness reference samples we determined the resolving power of superresolution microscopes and evaluated the sensitivity of smartphone cameras. To improve the sensitivity we created DNA origami optical antennas for metal enhanced fluorescence. The unique ability of our DNA origami nanoantennas to place molecular assays specifically in the plasmonic hotspot is used for detecting Zika-virus nucleic acids. The fluorescence enhancement is further exploited to achieve ultra-sensitive detection on low-cost devices such as a modified smartphone leading to the democratization of single-molecule detection.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74433115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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