{"title":"Comment on 'Robot-assisted partial nephrectomy using the Hugo™ RAS system: first multicentre study'.","authors":"Longtu Ma,Long Cheng,Zhilong Dong","doi":"10.1111/bju.70100","DOIUrl":"https://doi.org/10.1111/bju.70100","url":null,"abstract":"","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"29 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145644996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on ‘Feasibility of randomisation to radical prostatectomy or standard care in patients with metastatic prostate cancer’","authors":"Kun Zhao, Zhongze Zhou, Zhilong Dong","doi":"10.1111/bju.70097","DOIUrl":"https://doi.org/10.1111/bju.70097","url":null,"abstract":"","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"14 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145611102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective To assess the effect of structured perioperative nutritional optimisation on complication rates, recovery metrics, and body composition in patients undergoing radical cystectomy (RC) with urinary diversion. Patients and Methods In this prospective, randomised controlled trial, 74 patients scheduled for RC were allocated to either a nutritional optimisation group (NOG, n = 37) receiving individualised pre‐ and postoperative dietary interventions, or a standard care group (SCG, n = 37). Protocol included immunonutrition, caloric/protein adjustment, and close clinical and laboratory monitoring. The primary endpoint was overall complication rates within 30 days. Secondary endpoints included time to gastrointestinal recovery, length of hospital stay, wound healing time, nutritional markers, and body composition measurements. Results Baseline characteristics were comparable between the groups. Although the overall complication rate was lower in the NOG (54%) than SCG (68%), the difference was not statistically significant ( P = 0.236). Nutritional optimisation significantly accelerated gastrointestinal recovery; time to flatus (mean [SD] 39.6 [10.2] vs 64.8 [12.4] h, P < 0.001) and stool passage (mean [SD] 63.4 [12.1] vs 84.2 [13.8] h, P = 0.002) were shorter in the NOG. Length of stay (mean [SD] 7.78 [1.13] vs 10.59 [3.67] days, P = 0.002) and wound healing time (mean [SD] 14.22 [0.92] vs 15.5 [0.88] days, P < 0.001) were also significantly improved. The NOG maintained higher skeletal muscle mass and phase angle measurements at 30 days postoperatively ( P ≤ 0.007). Conclusions Structured perioperative nutritional optimisation significantly improved gastrointestinal recovery, reduced hospital stay, accelerated wound healing, and preserved skeletal muscle mass in patients undergoing RC.
目的探讨结构性围手术期营养优化对根治性膀胱切除术（RC）伴尿分流患者并发症发生率、恢复指标和体成分的影响。在这项前瞻性、随机对照试验中，74名计划进行RC的患者被分配到营养优化组（NOG, n = 37）和标准护理组（SCG, n = 37），分别接受个性化的术前和术后饮食干预。方案包括免疫营养，热量/蛋白质调整，密切的临床和实验室监测。主要终点是30天内的总并发症发生率。次要终点包括胃肠道恢复时间、住院时间、伤口愈合时间、营养指标和身体成分测量。结果两组间基线特征具有可比性。虽然NOG组的总并发症发生率（54%）低于SCG组（68%），但差异无统计学意义（P = 0.236）。营养优化显著加速胃肠恢复；NOG组的排气时间（平均[SD] 39.6[10.2]比64.8 [12.4]h, P < 0.001）和排便时间（平均[SD] 63.4[12.1]比84.2 [13.8]h, P = 0.002）更短。住院时间（平均[SD] 7.78 [1.13] vs 10.59[3.67]天，P = 0.002）和伤口愈合时间（平均[SD] 14.22 [0.92] vs 15.5[0.88]天，P < 0.001）也显著改善。术后30天NOG骨骼肌质量和相位角测量值保持较高（P≤0.007）。结论：有组织的围手术期营养优化显著改善了RC患者的胃肠道恢复，缩短了住院时间，加速了伤口愈合，并保留了骨骼肌质量。
{"title":"Impact of perioperative nutrition on recovery after radical cystectomy: a randomised trial","authors":"Mohammed Lotfi Amer, Ahmed Rabie Amer, Sameh Fawzy Elnasharty, Abdallah Atef Homouda, Asmaa Badr Eldin Opoda, Sohair Mostafa Soliman, Mohamed Hassan Radwan, Mohamed Abou Farha, Mohamed Elbendary Elnady","doi":"10.1111/bju.70094","DOIUrl":"https://doi.org/10.1111/bju.70094","url":null,"abstract":"Objective To assess the effect of structured perioperative nutritional optimisation on complication rates, recovery metrics, and body composition in patients undergoing radical cystectomy (RC) with urinary diversion. Patients and Methods In this prospective, randomised controlled trial, 74 patients scheduled for RC were allocated to either a nutritional optimisation group (NOG, <jats:italic>n</jats:italic> = 37) receiving individualised pre‐ and postoperative dietary interventions, or a standard care group (SCG, <jats:italic>n</jats:italic> = 37). Protocol included immunonutrition, caloric/protein adjustment, and close clinical and laboratory monitoring. The primary endpoint was overall complication rates within 30 days. Secondary endpoints included time to gastrointestinal recovery, length of hospital stay, wound healing time, nutritional markers, and body composition measurements. Results Baseline characteristics were comparable between the groups. Although the overall complication rate was lower in the NOG (54%) than SCG (68%), the difference was not statistically significant ( <jats:italic>P</jats:italic> = 0.236). Nutritional optimisation significantly accelerated gastrointestinal recovery; time to flatus (mean [SD] 39.6 [10.2] vs 64.8 [12.4] h, <jats:italic>P</jats:italic> < 0.001) and stool passage (mean [SD] 63.4 [12.1] vs 84.2 [13.8] h, <jats:italic>P</jats:italic> = 0.002) were shorter in the NOG. Length of stay (mean [SD] 7.78 [1.13] vs 10.59 [3.67] days, <jats:italic>P</jats:italic> = 0.002) and wound healing time (mean [SD] 14.22 [0.92] vs 15.5 [0.88] days, <jats:italic>P</jats:italic> < 0.001) were also significantly improved. The NOG maintained higher skeletal muscle mass and phase angle measurements at 30 days postoperatively ( <jats:italic>P</jats:italic> ≤ 0.007). Conclusions Structured perioperative nutritional optimisation significantly improved gastrointestinal recovery, reduced hospital stay, accelerated wound healing, and preserved skeletal muscle mass in patients undergoing RC.","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"58 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145611106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Authors’ reply to: comment on ‘Feasibility of randomisation to radical prostatectomy or standard care in patients with metastatic prostate cancer’","authors":"Lies Van den Eynde, Piet Ost, Nicolaas Lumen","doi":"10.1111/bju.70098","DOIUrl":"https://doi.org/10.1111/bju.70098","url":null,"abstract":"","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"150 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145611101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jonathan Kam, Yasmin Abu‐Ghanem, Francesco Del Guidice, Youssef Ibrahim, Elsie Mensah, Rajesh Nair, Muhammad Shamim Khan, Ramesh Thurairaja
Objective To present a novel technique for cystoscopic application of RADA16, a self‐assembling peptide that promotes both haemostasis and healing within the irradiated bladder, and describe its efficacy for intractable haematuria from radiation cystitis. Patients and Methods A total of 15 patients who had failed standard treatment for haematuria from radiation cystitis were offered this novel treatment at Guy's Hospital, London and Cleveland Clinic London, UK between February and October 2024. A standard saline cystoscopy was performed under general anaesthetic and the bladder emptied. CO 2 insufflation of the bladder was performed and the RADA16 deployed over the area of radiation telangiectasia. This was left for 5 min and then the gas evacuated from the bladder. Patients were followed up for a minimum of 3 months for complications and re‐bleeding. Results In all, 14 of the 15 patients had significant reduction in their bleeding at 6 weeks. One patient with ongoing bleeding proceeded to salvage cystectomy. Two patients required further cystodiathermy and RADA16 application within 3 months. No other modified Clavien–Dindo ≥III complications occurred within 3 months. Patients who had a follow‐up cystoscopy within 3 months of application showed significant regression of the radiation‐induced telangiectasia with no evidence of bladder scarring or ureteric orifice obstruction. Conclusions Cystoscopic application of RADA16 shows promise for treating intractable haematuria from radiation cystitis. It is the first treatment option that potentially provides both haemostasis as well as promoting bladder healing and regression of radiation‐induced telangiectasia.
{"title":"Cystoscopic application of RADA16 peptide for refractory haematuria from radiation cystitis","authors":"Jonathan Kam, Yasmin Abu‐Ghanem, Francesco Del Guidice, Youssef Ibrahim, Elsie Mensah, Rajesh Nair, Muhammad Shamim Khan, Ramesh Thurairaja","doi":"10.1111/bju.70075","DOIUrl":"https://doi.org/10.1111/bju.70075","url":null,"abstract":"Objective To present a novel technique for cystoscopic application of RADA16, a self‐assembling peptide that promotes both haemostasis and healing within the irradiated bladder, and describe its efficacy for intractable haematuria from radiation cystitis. Patients and Methods A total of 15 patients who had failed standard treatment for haematuria from radiation cystitis were offered this novel treatment at Guy's Hospital, London and Cleveland Clinic London, UK between February and October 2024. A standard saline cystoscopy was performed under general anaesthetic and the bladder emptied. CO <jats:sub>2</jats:sub> insufflation of the bladder was performed and the RADA16 deployed over the area of radiation telangiectasia. This was left for 5 min and then the gas evacuated from the bladder. Patients were followed up for a minimum of 3 months for complications and re‐bleeding. Results In all, 14 of the 15 patients had significant reduction in their bleeding at 6 weeks. One patient with ongoing bleeding proceeded to salvage cystectomy. Two patients required further cystodiathermy and RADA16 application within 3 months. No other modified Clavien–Dindo ≥III complications occurred within 3 months. Patients who had a follow‐up cystoscopy within 3 months of application showed significant regression of the radiation‐induced telangiectasia with no evidence of bladder scarring or ureteric orifice obstruction. Conclusions Cystoscopic application of RADA16 shows promise for treating intractable haematuria from radiation cystitis. It is the first treatment option that potentially provides both haemostasis as well as promoting bladder healing and regression of radiation‐induced telangiectasia.","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"59 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145611103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ricardo Almeida‐Magana, Larissa Sena Teixeira Mendes, Eoin Dinneen, Tarek Al‐Hammouri, Aiman Haider, Anna Silvanto, Alex Freeman, Nicholas Roberts, Louise Dickinson, Chun Wah So, Zafer Tandogdu, Benjamin W. Lamb, Nikhil Mayor, Mathias Winkler, Hashim Ahmed, Greg Shaw
Objectives To assess the feasibility of conducting a multicentre trial comparing NeuroSAFE with a novel technique based on confocal laser microscopy (LaserSAFE) and evaluate the diagnostic performance of LaserSAFE for real‐time surgical margin assessment. Patients and Methods This was a non‐randomised, prospective feasibility study conducted at a high‐volume academic UK centre ( ClinicalTrials.gov identifier: NCT06398470). Patients with localised prostate cancer (clinical T2–T3a N0 M0) scheduled for robot‐assisted radical prostatectomy and deemed unsuitable for bilateral intrafascial nerve sparing (NS) based on a multidisciplinary plan were included. LaserSAFE imaging was performed in the operating room after which the NeuroSAFE technique results guided NS decisions. Pathologists, blinded to NeuroSAFE and final histology, retrospectively evaluated LaserSAFE images. Diagnostic accuracy metrics and concordance between modalities were calculated. Feasibility was assessed based on recruitment rate and the ability to activate additional sites. Results A total of 20 patients were recruited at a single site within 12 months of recruitment start. However, expansion to additional centres was not feasible due to limitations in implementing the NeuroSAFE protocol. LaserSAFE achieved a sensitivity of 0.91 (95% confidence interval [CI] 0.59–1.00) and specificity of 1.00 (95% CI 0.88–1.00) for detecting positive surgical margins ≥0.5 mm. Cohen's kappa demonstrated strong agreement with NeuroSAFE and final pathology. LaserSAFE was completed within a median of 7 min, significantly shorter than the 63 min required for NeuroSAFE. Limitations include the small sample size, single‐centre setting, and lack of intraoperative decision‐making based on LaserSAFE findings. Conclusion While a multicentre study based on NeuroSAFE as a comparison was not achievable, LaserSAFE proved to be a rapid and accurate alternative for intraoperative margin assessment. These findings support the design of a larger trial in which NS decisions are informed by LaserSAFE, with a view to broadening access to real‐time margin assessment.
目的评估开展多中心试验比较NeuroSAFE与基于共聚焦激光显微镜（LaserSAFE）的新技术的可行性，并评估LaserSAFE在实时手术边缘评估中的诊断性能。患者和方法：这是一项在英国一个高容量学术中心进行的非随机、前瞻性可行性研究（ClinicalTrials.gov识别码：NCT06398470）。本研究纳入了计划接受机器人辅助根治性前列腺切除术的局限性前列腺癌患者（临床T2-T3a N0 M0），并基于多学科计划认为不适合双侧筋膜内神经保留（NS）。在手术室进行LaserSAFE成像，之后NeuroSAFE技术结果指导NS决策。病理学家对NeuroSAFE和最终组织学不知情，回顾性评估LaserSAFE图像。计算诊断准确性指标和模式之间的一致性。可行性是根据征聘率和激活其他地点的能力来评估的。结果在招募开始的12个月内，在单个地点共招募了20例患者。然而，由于实施NeuroSAFE方案的限制，扩展到其他中心是不可行的。LaserSAFE检测≥0.5 mm阳性手术切缘的灵敏度为0.91(95%可信区间[CI] 0.59-1.00)，特异性为1.00 （95% CI 0.88-1.00）。Cohen的kappa与NeuroSAFE和最终病理结果一致。LaserSAFE的平均完成时间为7分钟，明显短于NeuroSAFE所需的63分钟。局限性包括样本量小，单中心设置，以及缺乏基于LaserSAFE结果的术中决策。结论：虽然基于NeuroSAFE作为比较的多中心研究无法实现，但LaserSAFE被证明是术中边缘评估的快速和准确的替代方法。这些发现支持更大规模试验的设计，在该试验中，NS决策由LaserSAFE提供信息，以扩大实时边际评估的范围。
{"title":"The LaserSAFE technique for margin assessment during radical prostatectomy: a feasibility study","authors":"Ricardo Almeida‐Magana, Larissa Sena Teixeira Mendes, Eoin Dinneen, Tarek Al‐Hammouri, Aiman Haider, Anna Silvanto, Alex Freeman, Nicholas Roberts, Louise Dickinson, Chun Wah So, Zafer Tandogdu, Benjamin W. Lamb, Nikhil Mayor, Mathias Winkler, Hashim Ahmed, Greg Shaw","doi":"10.1111/bju.70092","DOIUrl":"https://doi.org/10.1111/bju.70092","url":null,"abstract":"Objectives To assess the feasibility of conducting a multicentre trial comparing NeuroSAFE with a novel technique based on confocal laser microscopy (LaserSAFE) and evaluate the diagnostic performance of LaserSAFE for real‐time surgical margin assessment. Patients and Methods This was a non‐randomised, prospective feasibility study conducted at a high‐volume academic UK centre ( <jats:ext-link xmlns:xlink=\"http://www.w3.org/1999/xlink\" xlink:href=\"http://clinicaltrials.gov\">ClinicalTrials.gov</jats:ext-link> identifier: NCT06398470). Patients with localised prostate cancer (clinical T2–T3a N0 M0) scheduled for robot‐assisted radical prostatectomy and deemed unsuitable for bilateral intrafascial nerve sparing (NS) based on a multidisciplinary plan were included. LaserSAFE imaging was performed in the operating room after which the NeuroSAFE technique results guided NS decisions. Pathologists, blinded to NeuroSAFE and final histology, retrospectively evaluated LaserSAFE images. Diagnostic accuracy metrics and concordance between modalities were calculated. Feasibility was assessed based on recruitment rate and the ability to activate additional sites. Results A total of 20 patients were recruited at a single site within 12 months of recruitment start. However, expansion to additional centres was not feasible due to limitations in implementing the NeuroSAFE protocol. LaserSAFE achieved a sensitivity of 0.91 (95% confidence interval [CI] 0.59–1.00) and specificity of 1.00 (95% CI 0.88–1.00) for detecting positive surgical margins ≥0.5 mm. Cohen's kappa demonstrated strong agreement with NeuroSAFE and final pathology. LaserSAFE was completed within a median of 7 min, significantly shorter than the 63 min required for NeuroSAFE. Limitations include the small sample size, single‐centre setting, and lack of intraoperative decision‐making based on LaserSAFE findings. Conclusion While a multicentre study based on NeuroSAFE as a comparison was not achievable, LaserSAFE proved to be a rapid and accurate alternative for intraoperative margin assessment. These findings support the design of a larger trial in which NS decisions are informed by LaserSAFE, with a view to broadening access to real‐time margin assessment.","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"7 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145611132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The objective of this study is to address the lack of real-life study comparing the impact of the three surgical approaches for radical prostatectomy (RP), i.e., open (ORP), laparoscopic (LRP) and robot-assisted (RARP), on the occurrence of postoperative events by measuring the association between surgical approach and risk of death, transfer to an intensive care unit (ICU), or complications during hospitalisation for RP.
Patients and methods
This study used the French National Health Data System (Système National des Données de Santé [SNDS]) to study the 38 481 patients who underwent a RP in French hospitals in 2020–2021. The primary endpoint was the occurrence of any event (death, ICU admission, or complications) during hospitalisation for RP. Secondary endpoints were the occurrence of death, ICU admission, complications, and each of the complication subtypes. Outcomes were analysed by uni- and multivariable logistic regression.
Results
A RARP was associated with the lowest risk of an event during hospitalisation, followed by LRP compared with ORP (adjusted odds ratio [aOR] 0.51, 95% confidence interval [CI] 0.48–0.55; and aOR 0.63, 95% CI 0.58–0.68, respectively). RARP was associated with a reduction in the risk of most complications compared with ORP. Minimally-invasive procedures were associated with an increased risk of hernia. To the best of our knowledge, this is the first French nationwide study of its sort and limitations are related to the observational nature of our study, the use of a medico-administrative database, and the length of follow-up. To confirm the main results 30-day sensitivity analyses were performed.
Conclusions
There were significantly fewer short-term postoperative events for RARP. Additional studies with a longer follow-up period are required to investigate the medium- and long-term risks.
本研究的目的是通过测量手术入路与死亡风险、转入重症监护病房（ICU）或RP住院期间并发症之间的关系，来解决缺乏真实生活研究比较根治性前列腺切除术（RP）的三种手术入路，即开放（ORP）、腹腔镜（LRP）和机器人辅助（RARP）对术后事件发生的影响的问题。患者和方法本研究使用法国国家健康数据系统（system National des donnsamuess [SNDS]）对2020-2021年在法国医院接受RP的38481例患者进行了研究。主要终点是RP住院期间发生的任何事件（死亡、ICU入院或并发症）。次要终点为死亡发生率、ICU入院率、并发症发生率和各并发症亚型。结果通过单变量和多变量logistic回归分析。结果RARP与住院期间事件的最低风险相关，其次是LRP与ORP（调整比值比[aOR] 0.51, 95%可信区间[CI] 0.48-0.55； aOR为0.63,95%可信区间[CI] 0.58-0.68）。与ORP相比，RARP与大多数并发症的风险降低有关。微创手术与疝气风险增加相关。据我们所知，这是法国第一个此类全国性研究，其局限性与我们研究的观察性、医学管理数据库的使用以及随访时间长短有关。为了确认主要结果，进行了30天敏感性分析。结论RARP术后短期事件显著减少。需要进行更长随访期的额外研究来调查中期和长期风险。
{"title":"Comparison of short-term complications after open, laparoscopic and robot-assisted radical prostatectomy","authors":"Prescillia Nunes, François Richaud, Catherine Quantin, Christine Binquet, Luc Cormier, Anne-Sophie Mariet","doi":"10.1111/bju.70076","DOIUrl":"10.1111/bju.70076","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>The objective of this study is to address the lack of real-life study comparing the impact of the three surgical approaches for radical prostatectomy (RP), i.e., open (ORP), laparoscopic (LRP) and robot-assisted (RARP), on the occurrence of postoperative events by measuring the association between surgical approach and risk of death, transfer to an intensive care unit (ICU), or complications during hospitalisation for RP.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Patients and methods</h3>\u0000 \u0000 <p>This study used the French National Health Data System (Système National des Données de Santé [SNDS]) to study the 38 481 patients who underwent a RP in French hospitals in 2020–2021. The primary endpoint was the occurrence of any event (death, ICU admission, or complications) during hospitalisation for RP. Secondary endpoints were the occurrence of death, ICU admission, complications, and each of the complication subtypes. Outcomes were analysed by uni- and multivariable logistic regression.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A RARP was associated with the lowest risk of an event during hospitalisation, followed by LRP compared with ORP (adjusted odds ratio [aOR] 0.51, 95% confidence interval [CI] 0.48–0.55; and aOR 0.63, 95% CI 0.58–0.68, respectively). RARP was associated with a reduction in the risk of most complications compared with ORP. Minimally-invasive procedures were associated with an increased risk of hernia. To the best of our knowledge, this is the first French nationwide study of its sort and limitations are related to the observational nature of our study, the use of a medico-administrative database, and the length of follow-up. To confirm the main results 30-day sensitivity analyses were performed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>There were significantly fewer short-term postoperative events for RARP. Additional studies with a longer follow-up period are required to investigate the medium- and long-term risks.</p>\u0000 </section>\u0000 </div>","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"137 2","pages":"348-359"},"PeriodicalIF":4.4,"publicationDate":"2025-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://bjui-journals.onlinelibrary.wiley.com/doi/epdf/10.1111/bju.70076","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145611087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to ‘Functional outcomes of robot‐assisted partial nephrectomy in patients with a solitary kidney’","authors":"","doi":"10.1111/bju.70095","DOIUrl":"https://doi.org/10.1111/bju.70095","url":null,"abstract":"","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"1 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145599701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to “Outcomes of BCG vs upfront radical cystectomy for high‐risk non‐muscle‐invasive bladder cancer”","authors":"","doi":"10.1111/bju.70090","DOIUrl":"https://doi.org/10.1111/bju.70090","url":null,"abstract":"","PeriodicalId":8985,"journal":{"name":"BJU International","volume":"191 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2025-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145594207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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