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The effect of varying the position of implant screw access opening on the stress distribution of sealing composite resin: a 3D-FEA study. 不同种植体螺钉通路开口位置对密封复合树脂应力分布影响的3D-FEA研究。
IF 3.1 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-16 DOI: 10.1186/s12903-026-07696-x
Feifan Li, Meiqi Wu, Xiya Zhang, Mengfei Bi, Ming Shen, Zhixuan Zhou
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引用次数: 0
Surgical removal of unexpected oral squamous cell carcinoma arising from a maxillary odontogenic keratocyst in a young female patient: a case report and literature review. 一例年轻女性上颌牙源性角化囊肿意外引起的口腔鳞状细胞癌手术切除:1例报告及文献复习。
IF 3.1 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-15 DOI: 10.1186/s12903-025-07562-2
Tasneem A Amer, Mai M Saleh, Mohammed S Alalfy
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引用次数: 0
Oral health needs and oral healthcare utilization among newly arrived Ukrainian refugees in Poland: a retrospective EHR-based study. 新近抵达波兰的乌克兰难民的口腔健康需求和口腔保健利用:一项基于ehr的回顾性研究。
IF 3.1 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-15 DOI: 10.1186/s12903-026-07672-5
Katarzyna Lewtak, Alicja Chowaniec-Prażuch, Izabela Rhone, Anna Klukowska, Inna Kucherenko, Emir Chehertma, Krzysztof Kanecki, Aneta Nitsch-Osuch

Background: Oral health, recognized as an essential component of overall health, quality of life, and a fundamental human right, is one of the most neglected aspects of refugee health. This study aimed to analyze the oral health status and dental care utilization patterns among newly arrived Ukrainian refugees in Poland during the first 100 days of the war.

Methods: This study utilized data from electronic health records (EHR) of all in-person dental visits by Ukrainian war refugees in Poland between February 24 and June 4, 2022. The data are presented using descriptive statistics.

Results: A total of 5,242 Ukrainian war refugees (mean age 28.8 ± 18.3 years [range: 1-95 years]; 1,792 [34.2%] minors; 3,954 [75.4%] female) were included in the analysis. During the first 100 days of the war, 8,811 dental visits were recorded, out of which 31.3% involved pediatric patients. The average number of appointments per patient was 1.7 overall (1.5 ± 0.9 [range: 1-8] for children; 1.8 ± 1.3 [range: 1-12] for adults). Dental caries (ICD-10: K02) was the most common diagnosis, affecting 63.1% of children and 65.4% of adults, followed by diseases of the pulp and periapical tissues (K04), which were significantly more prevalent in pediatric patients (44.5% vs. 37.5%, p < 0.001). Composite or protective restorations were received by 50.5% of children and 48.8% of adults. Tooth extractions occurred more frequently in pediatric patients (20.5% vs. 13.4%, p < 0.001), while endodontic therapy was provided to 12.5% of children and 11.2% of adults. About 27.1% of refugee children and 28.2% of adults required dental care across three or more service categories. Pediatric patients were statistically more likely than adults to have three or more teeth treated during the study period (11.4% vs. 6.5%, p < 0.001).

Conclusions: The data presented in this study provide important insights into the oral health needs of newly arrived Ukrainian refugees, particularly in terms of dental emergencies, during the early days of the conflict, and contribute to closing a research gap. This evidence can guide host countries in planning multisectoral interventions and delivering targeted dental care that meets the identified needs, promoting oral health and reducing inequalities among conflict-displaced populations.

背景:口腔健康被认为是整体健康、生活质量和一项基本人权的重要组成部分,但却是难民健康中最被忽视的方面之一。本研究旨在分析战争前100天抵达波兰的乌克兰难民的口腔健康状况和牙科保健利用模式。方法:本研究利用了2022年2月24日至6月4日期间所有乌克兰战争难民在波兰亲自牙科就诊的电子健康记录(EHR)数据。这些数据是用描述性统计来表示的。结果:共纳入乌克兰战争难民5242例(平均年龄28.8±18.3岁,年龄范围1 ~ 95岁),未成年1792例(34.2%),女性3954例(75.4%)。在战争的前100天,记录了8,811次牙科就诊,其中31.3%涉及儿科患者。每位患者的平均预约次数为1.7次(儿童为1.5±0.9次[范围:1-8次];成人为1.8±1.3次[范围:1-12次])。龋齿(ICD-10: K02)是最常见的诊断,影响63.1%的儿童和65.4%的成人,其次是牙髓和根尖周组织疾病(K04),在儿童患者中患病率明显更高(44.5%比37.5%),p。本研究中提供的数据为了解新抵达的乌克兰难民的口腔健康需求提供了重要见解,特别是在冲突初期的牙科紧急情况方面,并有助于缩小研究差距。这些证据可以指导东道国规划多部门干预措施,提供有针对性的牙科护理,以满足确定的需求,促进口腔健康,减少冲突流离失所者之间的不平等现象。
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引用次数: 0
Novel coating materials for glassionomer cement: formulation characteristics, surface adhesion and impact on microhardness. 新型玻璃聚合物水泥涂层材料:配方特性、表面附着力及对显微硬度的影响。
IF 3.1 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-15 DOI: 10.1186/s12903-025-07639-y
Yasemin Yiğit, Ece Eden, Meliha Güneş, Derviş Birim, Güliz Armagan, Sinem Yaprak Karavana
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引用次数: 0
Debonding of the orthodontic brackets; is diode laser a safer method? Experimental invitro study. 正畸托槽的脱粘;二极管激光是更安全的方法吗?实验体外研究。
IF 3.1 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-15 DOI: 10.1186/s12903-025-07516-8
Eman M Salem, S M Khattab

Bracket debonding remains a clinical challenge in orthodontics, particularly when removing ceramic brackets, due to the potential risk of enamel cracks and surface damage. Recently, laser-assisted techniques have been investigated to facilitate safer and less traumatic bracket removal. This study aimed to evaluate the effect of 940 nm diode laser irradiation on the debonding process of metallic and ceramic orthodontic brackets by assessing shear bond strength (SBS) and enamel surface morphology using scanning electron microscopy (SEM).

Methods: Thirty two extracted human premolars were randomly divided into four experimental groups: Group A (Control-Metallic),Group B (Control-Ceramic),Group C (Laser-Metallic), and Group D (Laser-Ceramic).Brackets were bonded using a light-cured adhesive and subjected to diode laser irradiation at 940 nm, 1 W, for 5 seconds in the laser-treated groups. SBS was measured using a universal testing machine at a crosshead speed of 1 mm/min, and mean values were expressed in MPa. Enamel surface morphology was analyzed using SEM at 80× and 1000× magnifications. Statistical analysis was performed using one-way ANOVA and independent t-tests with a significance level of p < 0.05.

Results: Laser-assisted debonding significantly reduced SBS in metallic brackets (mean ± SD: 2.4 ± 0.3 MPa) compared with the control group (4.3 ± 0.4 MPa) (p < 0.05). In contrast, the difference between laser-treated and control ceramic brackets was not statistically significant. SEM observations revealed smoother enamel surfaces and fewer cracks in the laser-treated groups compared with controls.

Conclusions: Diode laser-assisted debonding (940 nm, 1 W) effectively decreases shear bond strength for metallic brackets and minimizes enamel surface alterations, suggesting it is a promising adjunct for safer bracket removal. However, the technique's effect on ceramic brackets appears limited at this power setting.

由于牙釉质裂纹和表面损伤的潜在风险,托架脱粘仍然是正畸学的临床挑战,特别是当去除陶瓷托架时。最近,人们研究了激光辅助技术,以实现更安全、创伤更小的支架移除。本研究旨在通过扫描电镜(SEM)观察剪切结合强度(SBS)和牙釉质表面形貌,评价940 nm二极管激光照射对金属和陶瓷正畸托槽脱粘过程的影响。方法:将32颗拔除的人前磨牙随机分为4个实验组:A组(对照组-金属)、B组(对照组-陶瓷)、C组(激光-金属)和D组(激光-陶瓷)。用光固化胶粘剂粘合支架,并在激光处理组中进行940 nm, 1 W的二极管激光照射5秒。SBS采用万能试验机测量,十字速度为1 mm/min,平均值以MPa表示。用扫描电镜观察牙釉质在80倍和1000倍放大率下的表面形态。统计学分析采用单因素方差分析和独立t检验,显著性水平p < 0.05。结果:与对照组(4.3±0.4 MPa)相比,激光辅助脱粘可显著降低金属托槽的SBS(平均±SD: 2.4±0.3 MPa) (p < 0.05)。相比之下,激光处理和对照陶瓷支架之间的差异无统计学意义。扫描电镜观察显示,与对照组相比,激光治疗组的牙釉质表面更光滑,裂缝更少。结论:二极管激光辅助脱粘(940 nm, 1 W)有效降低金属托槽的剪切粘接强度,最大限度地减少牙釉质表面的改变,表明这是一种有前途的辅助方法,可以更安全地去除托槽。然而,在这种功率设置下,该技术对陶瓷支架的影响似乎有限。
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引用次数: 0
Establishment of a three-dimensional in vitro peri-implant bone-mucosa composite model. 三维体外种植体周围骨-黏膜复合模型的建立。
IF 3.1 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-14 DOI: 10.1186/s12903-025-06930-2
Behnaz Malekahmadi, Marjan Kheirmand-Parizi, Carina Mikolai, Andreas Winkel, Muhammad Imran Rahim, Katharina Doll-Nikutta, Andreas Kampmann, Nils-Claudius Gellrich, Dagmar Wirth, Henning Menzel, Meike Stiesch
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引用次数: 0
Finite element study on the effect of bruxism on the fracture resistance of maxillary zirconia fixed partial dentures with varying anterior inter-implant distances. 磨牙对不同种植间距的上颌氧化锆固定义齿抗骨折性影响的有限元研究。
IF 3.1 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-14 DOI: 10.1186/s12903-026-07678-z
Omir Aldowah, Mohammed Zarbah, Abdulrahman Aseri, Ahmed Almeshari, Mohamed I El-Anwar, Abdel Naser M Emam, Hussain Alharthi

Objective: This study aims to investigate the effect of bruxism on the fracture resistance of maxillary zirconia fixed denture prostheses (FDP) with different inter-implant distances and different occlusion types.

Methods: We developed four finite element models that reflect maxillary fixed dental prostheses in patients with bruxism. The original version retains the prosthesis using six implants positioned at the canines, premolars, and first molars. The second one features implants positioned at the lateral incisors, canines, and second premolars. The development of two supplementary models, 3 and 4, included a reduction of the cusp height by 0.35 mm. Angle's classification, encompassing classes I, II, and III, directs the application of pressures to all models subjected to parafunctional habits, including bruxism.

Results: Model 1 exhibited the lowest values for FDP and bone deformation, measuring 77 μm and 27 μm, respectively. Model 3 followed with values ranging from 71 to 73 μm for FDP and 25 to 26 μm for bone deformation. In contrast, Models 2 and 4 demonstrated higher values, with Model 2 showing particularly elevated measurements of 104 μm for FDP and 43 μm for bone deformation. In Models 2 and 3, the Von Mises stress in the FDP was less than 500 MPa, suggesting a less risk of fatigue, whereas Models 1 and 4 surpassed this threshold. Models 1 and 3 exhibited physiological bone stress, whereas Models 2 and 4 demonstrated unsafe levels indicative of potential structural damage. Class I and II occlusions exhibited stable, low-stress profiles, while Class III occlusions resulted in increased shear and torque due to anterior occlusal displacement. This underscores the importance of occlusion-specific prosthetic design to mitigate peri-implant stress.

Conclusions: The distribution of implants in Models 1 and 3 may enhance stability and extend longevity. A 350-micron reduction in occlusal surface height was associated with reduced stress and deformation in the models, which may enhance the lifespan of the FDPs. Therefore, reducing the occlusal surface height of FDP is recommended for patients with bruxism.

Clinical significance: It is recommended that clinicians construct maxillary zirconia FDPs with a broader implant distribution and a cusp inclination of (≤ 15º) for better outcomes in patients with bruxism. This configuration enhances prosthetic stability and reduces stress, thereby increasing longevity. Clinical protocols may encompass strategic implant placement, reduction of cusp height, and individualized occlusal design.

目的:研究磨牙对不同种植间距和不同咬合类型的上颌氧化锆固定义齿(FDP)抗骨折性的影响。方法:建立反映磨牙患者上颌固定修复体的四个有限元模型。原始版本保留假体,使用放置在犬齿,前磨牙和第一磨牙的六个种植体。第二种植体位于侧门牙、犬齿和第二前磨牙。两个补充型号3和4的开发,包括将尖端高度降低0.35毫米。Angle的分类,包括I, II和III类,将压力应用于所有受功能习惯影响的模型,包括磨牙症。结果:模型1的FDP和骨变形最小,分别为77 μm和27 μm。模型3中FDP值为71 ~ 73 μm,骨变形值为25 ~ 26 μm。相比之下,模型2和4显示出更高的值,模型2显示出特别高的FDP测量值为104 μm,骨变形测量值为43 μm。在模型2和模型3中,FDP的Von Mises应力小于500 MPa,表明疲劳风险较小,而模型1和模型4超过了这个阈值。模型1和3显示生理性骨应力,而模型2和4显示不安全水平,表明潜在的结构损伤。I类和II类咬合表现出稳定的低应力轮廓,而III类咬合由于前牙合位移导致剪切和扭矩增加。这强调了咬合特异性假体设计对于减轻种植体周围应力的重要性。结论:模型1和模型3种植体的分布可以提高稳定性和延长寿命。咬合面高度降低350微米与模型中的应力和变形减少有关,这可能会延长fdp的寿命。因此,磨牙患者建议降低FDP的咬合面高度。临床意义:建议临床医生在磨牙患者中构建种植体分布更广、牙尖倾角≤15º的上颌氧化锆fdp,以获得更好的治疗效果。这种结构增强了假体的稳定性,减少了压力,从而延长了使用寿命。临床方案可能包括战略性种植体放置、降低牙尖高度和个性化的咬合设计。
{"title":"Finite element study on the effect of bruxism on the fracture resistance of maxillary zirconia fixed partial dentures with varying anterior inter-implant distances.","authors":"Omir Aldowah, Mohammed Zarbah, Abdulrahman Aseri, Ahmed Almeshari, Mohamed I El-Anwar, Abdel Naser M Emam, Hussain Alharthi","doi":"10.1186/s12903-026-07678-z","DOIUrl":"https://doi.org/10.1186/s12903-026-07678-z","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to investigate the effect of bruxism on the fracture resistance of maxillary zirconia fixed denture prostheses (FDP) with different inter-implant distances and different occlusion types.</p><p><strong>Methods: </strong>We developed four finite element models that reflect maxillary fixed dental prostheses in patients with bruxism. The original version retains the prosthesis using six implants positioned at the canines, premolars, and first molars. The second one features implants positioned at the lateral incisors, canines, and second premolars. The development of two supplementary models, 3 and 4, included a reduction of the cusp height by 0.35 mm. Angle's classification, encompassing classes I, II, and III, directs the application of pressures to all models subjected to parafunctional habits, including bruxism.</p><p><strong>Results: </strong>Model 1 exhibited the lowest values for FDP and bone deformation, measuring 77 μm and 27 μm, respectively. Model 3 followed with values ranging from 71 to 73 μm for FDP and 25 to 26 μm for bone deformation. In contrast, Models 2 and 4 demonstrated higher values, with Model 2 showing particularly elevated measurements of 104 μm for FDP and 43 μm for bone deformation. In Models 2 and 3, the Von Mises stress in the FDP was less than 500 MPa, suggesting a less risk of fatigue, whereas Models 1 and 4 surpassed this threshold. Models 1 and 3 exhibited physiological bone stress, whereas Models 2 and 4 demonstrated unsafe levels indicative of potential structural damage. Class I and II occlusions exhibited stable, low-stress profiles, while Class III occlusions resulted in increased shear and torque due to anterior occlusal displacement. This underscores the importance of occlusion-specific prosthetic design to mitigate peri-implant stress.</p><p><strong>Conclusions: </strong>The distribution of implants in Models 1 and 3 may enhance stability and extend longevity. A 350-micron reduction in occlusal surface height was associated with reduced stress and deformation in the models, which may enhance the lifespan of the FDPs. Therefore, reducing the occlusal surface height of FDP is recommended for patients with bruxism.</p><p><strong>Clinical significance: </strong>It is recommended that clinicians construct maxillary zirconia FDPs with a broader implant distribution and a cusp inclination of (≤ 15º) for better outcomes in patients with bruxism. This configuration enhances prosthetic stability and reduces stress, thereby increasing longevity. Clinical protocols may encompass strategic implant placement, reduction of cusp height, and individualized occlusal design.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145970666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic performance of convolutional neural network-based AI in detecting oral squamous cell carcinoma: a meta-analysis. 基于卷积神经网络的人工智能在口腔鳞状细胞癌诊断中的表现:一项荟萃分析。
IF 3.1 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-14 DOI: 10.1186/s12903-025-07543-5
Mi Shen, Zhili Jiang, Yankun Feng, Zhenzhen Lin, Cancan Lu, Junli Sun, Jun Yao, Liang Hu, Jincai Guo

Purpose: To evaluate the diagnostic accuracy of artificial intelligence (AI) based on convolutional neural network (CNN) in diagnosing oral squamous cell carcinoma (OSCC), we carried out this meta-analysis.

Methods: We searched PubMed, Embase, Web of Science, ProQuest, Cochrane Library, and Scopus to identify relevant articles from database inception to April 2025. Studies assessing the diagnostic accuracy of AI based on CNN to detect OSCC were included in this search. Statistical analyses were performed by using the Meta-Disc (version 1.4) and Stata 18.0 software.

Results: A total of 14 studies with 61,372 samples were included in the analysis. The pooled positive likelihood ratio (PLR) of 13.08 (95% CI 9.21-18.60) and negative likelihood ratio (NLR) of 0.06 (95% CI 0.03-0.10) were observed with a diagnostic odds ratio of 261.58 (95% CI 131.03-522.19) and the area under the curve being 0.98, respectively. The pooled sensitivity and specificity of CNN based AI in detecting OSCC were 0.94 (95% CI 0.89-0.98) and 0.94 (95% CI 0.92-0.97). Heterogeneity was observed (I² > 75%). Subgroup analyses revealed variations in diagnostic performance based on study design, cancer site, statistical method, external validation, and sample size. The Fagan nomogram indicated that when the pre-test probability was set at 20%, the post-test probability could increase to 81%.

Conclusion: In detecting OSCC, CNN-based AI demonstrates a high diagnostic performance. These findings suggest that CNN models, though not yet widely implemented in routine diagnostic workflows, hold strong potential for OSCC detection. However, the current evidence is largely based on retrospective studies with limited sample sizes and methodological variability, and only one study performed external validation. Therefore, larger prospective and multicenter studies are needed before clinical translation.

目的:评价基于卷积神经网络(CNN)的人工智能(AI)诊断口腔鳞状细胞癌(OSCC)的准确性,进行meta分析。方法:检索PubMed、Embase、Web of Science、ProQuest、Cochrane Library、Scopus等数据库,确定从建库到2025年4月的相关文章。评估基于CNN的人工智能检测OSCC诊断准确性的研究被纳入本检索。采用Meta-Disc (version 1.4)和Stata 18.0软件进行统计分析。结果:共纳入14项研究,61372份样本。合并阳性似然比(PLR)为13.08 (95% CI 9.21 ~ 18.60),阴性似然比(NLR)为0.06 (95% CI 0.03 ~ 0.10),诊断优势比为261.58 (95% CI 131.03 ~ 522.19),曲线下面积为0.98。基于CNN的人工智能检测OSCC的敏感性和特异性分别为0.94 (95% CI 0.89-0.98)和0.94 (95% CI 0.92-0.97)。观察到异质性(I²> 75%)。亚组分析揭示了基于研究设计、癌症部位、统计方法、外部验证和样本量的诊断表现差异。Fagan图显示,当前测概率为20%时,后测概率可增加到81%。结论:基于cnn的人工智能在OSCC检测中具有较高的诊断性能。这些发现表明,CNN模型虽然尚未在常规诊断工作流程中广泛应用,但在OSCC检测方面具有很强的潜力。然而,目前的证据主要是基于有限样本量和方法可变性的回顾性研究,只有一项研究进行了外部验证。因此,在临床转化之前,需要更大的前瞻性和多中心研究。
{"title":"Diagnostic performance of convolutional neural network-based AI in detecting oral squamous cell carcinoma: a meta-analysis.","authors":"Mi Shen, Zhili Jiang, Yankun Feng, Zhenzhen Lin, Cancan Lu, Junli Sun, Jun Yao, Liang Hu, Jincai Guo","doi":"10.1186/s12903-025-07543-5","DOIUrl":"https://doi.org/10.1186/s12903-025-07543-5","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the diagnostic accuracy of artificial intelligence (AI) based on convolutional neural network (CNN) in diagnosing oral squamous cell carcinoma (OSCC), we carried out this meta-analysis.</p><p><strong>Methods: </strong>We searched PubMed, Embase, Web of Science, ProQuest, Cochrane Library, and Scopus to identify relevant articles from database inception to April 2025. Studies assessing the diagnostic accuracy of AI based on CNN to detect OSCC were included in this search. Statistical analyses were performed by using the Meta-Disc (version 1.4) and Stata 18.0 software.</p><p><strong>Results: </strong>A total of 14 studies with 61,372 samples were included in the analysis. The pooled positive likelihood ratio (PLR) of 13.08 (95% CI 9.21-18.60) and negative likelihood ratio (NLR) of 0.06 (95% CI 0.03-0.10) were observed with a diagnostic odds ratio of 261.58 (95% CI 131.03-522.19) and the area under the curve being 0.98, respectively. The pooled sensitivity and specificity of CNN based AI in detecting OSCC were 0.94 (95% CI 0.89-0.98) and 0.94 (95% CI 0.92-0.97). Heterogeneity was observed (I² > 75%). Subgroup analyses revealed variations in diagnostic performance based on study design, cancer site, statistical method, external validation, and sample size. The Fagan nomogram indicated that when the pre-test probability was set at 20%, the post-test probability could increase to 81%.</p><p><strong>Conclusion: </strong>In detecting OSCC, CNN-based AI demonstrates a high diagnostic performance. These findings suggest that CNN models, though not yet widely implemented in routine diagnostic workflows, hold strong potential for OSCC detection. However, the current evidence is largely based on retrospective studies with limited sample sizes and methodological variability, and only one study performed external validation. Therefore, larger prospective and multicenter studies are needed before clinical translation.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145970629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Topical 0.02% mitomycin in postoperative healing of oral submucous fibrosis treated with fibrous band release and buccal fat pad reconstruction: a pilot split-mouth study. 局部应用0.02%丝裂霉素治疗口腔黏膜下纤维化术后纤维带释放和颊脂肪垫重建:一项口裂试验研究。
IF 3.1 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-14 DOI: 10.1186/s12903-025-07630-7
Ankita Chugh, Amanjot Kaur, Gigi Pg, Pravin Kumar

Background: Topical application of 0.02% Mitomycin-C (MMC) has demonstrated efficacy in reducing fibrosis in ophthalmic and laryngeal procedures. This pilot study aimed to evaluate the potential role of MMC in enhancing healing outcomes in patients with Oral Submucous Fibrosis (OSMF) following surgical release of fibrous bands and reconstruction with the Buccal Fat Pad (BFP).

Methodology: A prospective, double-blinded, split-mouth feasibility pilot study was conducted on 10 patients diagnosed with OSMF. Each patient underwent surgical release of fibrous bands and/or coronoidectomy under general anaesthesia, followed by BFP reconstruction bilaterally. The right buccal mucosa (study side) received topical application of 0.02% MMC (0.2 mg/ml) twice, first, for 5 min over the raw surgical site before BFP placement, and again after 10 days for 3 min over the healing mucosa. The left side (control) received a placebo (normal saline) following the same protocol. Patients were assessed over three months for mucosal pliability, cheek flexibility, mucosal colouration and mouth opening.

Results: However, despite the theoretical antifibrotic potential of MMC, no statistically significant difference was observed between the MMC-treated and control sides with respect to mucosal pliability or cheek flexibility at any postoperative interval. Although preoperative cheek flexibility (4 ± 0.67 mm) demonstrated initial postoperative improvement, this was not sustained during follow-up, and the MMC application did not confer any measurable long-term advantage over placebo. Additionally, mucosal coloration remained stable and comparable on both sides, indicating no clinically discernible enhancement in mucosal healing attributable to MMC. Notably, no adverse tissue reactions or complications were associated with MMC use, supporting its local biocompatibility. Postoperative mouth opening showed significant improvement from a baseline of 16 ± 2.79 mm to 38.4 ± 1.58 mm at 1 week (T1), 36.1 ± 1.85 mm at 1 month (T2), and 33 ± 2.11 mm at 3 months (T3).

Conclusion: These findings suggest that while MMC is safe for intraoral application at this concentration, its therapeutic efficacy in mitigating fibrosis in the OSMF surgical site remains inconclusive, warranting further investigation through larger, controlled trials.

Trial registration: Clinical Trials Registry- India registration (CTRI/2022/04/041738) dated 08/04/2022).

背景:局部应用0.02%丝裂霉素c (MMC)在眼科和喉部手术中显示出减少纤维化的疗效。本初步研究旨在评估MMC在口腔黏膜下纤维化(OSMF)患者手术释放纤维带和口腔脂肪垫(BFP)重建后提高愈合结果的潜在作用。方法:对10例诊断为OSMF的患者进行前瞻性、双盲、裂口可行性初步研究。每位患者均在全身麻醉下行纤维带松解术和/或冠状突切除术,随后行双侧BFP重建。右颊粘膜(研究侧)局部应用0.02% MMC (0.2 mg/ml)两次,第一次在BFP放置前在未愈合的手术部位上涂抹5分钟,10天后再次在愈合的粘膜上涂抹3分钟。左侧(对照组)按照相同的方案接受安慰剂(生理盐水)。在三个月的时间里,对患者进行了粘膜柔韧性、脸颊柔韧性、粘膜颜色和口腔张开度的评估。结果:然而,尽管理论上MMC具有抗纤维化潜力,但在术后任何时间间隔,MMC治疗组和对照组在粘膜柔韧性或脸颊柔韧性方面均未观察到统计学上的显著差异。虽然术前脸颊柔韧性(4±0.67 mm)显示了术后的初步改善,但在随访期间没有持续,MMC的应用并没有比安慰剂带来任何可测量的长期优势。此外,两侧的粘膜颜色保持稳定和可比性,表明临床上没有明显的MMC引起的粘膜愈合增强。值得注意的是,没有不良组织反应或并发症与MMC使用相关,支持其局部生物相容性。术后口腔开口在1周(T1)、1个月(T2)和3个月(T3)时分别从16±2.79 mm、36.1±1.85 mm和33±2.11 mm显著改善至38.4±1.58 mm。结论:这些研究结果表明,虽然MMC在该浓度下口服是安全的,但其减轻OSMF手术部位纤维化的治疗效果仍不确定,需要通过更大规模的对照试验进行进一步研究。试验注册:临床试验注册-印度注册(CTRI/2022/04/041738),日期为2022年4月8日)。
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引用次数: 0
A scoping review of crowdsourcing and collective intelligence in oral healthcare. 口腔保健中的众包和集体智慧的范围审查。
IF 3.1 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-14 DOI: 10.1186/s12903-026-07670-7
Rodrigo J Mariño, Max Ganhewa, Alison Lau, Randal von Marttens, Nicola Cirillo

Objective: Diagnostic and treatment errors are detrimental yet relatively common in primary healthcare settings. Crowdsourcing and collective intelligence (CI) in the form of peers' opinion and group decision-making can lead to modifications in diagnosis and treatment planning by dentists. In this review, it was explored their use in oral healthcare delivery, investigating specific applications and evaluating their merits and drawbacks in oral healthcare.

Methods: A scoping review approach was chosen as the optimal study design, due to the complexity of the topic. A literature search from 1980 to December 2024 using selected search terms and a search strategy was implemented across six databases: Medline, Scopus, Web of Science, SciELO, LILACS, and CINAHL. Inclusion criteria specified studies published in English, Spanish, and Portuguese, focusing on CI applications in oral healthcare settings.

Results: Of the 265 identified studies, 63 abstracts and 20 full-text studies were screened, and 7 studies were included in the qualitative synthesis. The findings suggest that CI may significantly enhance patient management in primary healthcare settings by employing various group decision-making models such as multidisciplinary teams (MDTs) and the Delphi method. MDTs, comprising professionals from different disciplines, can enhance patient care through collaborative problem-solving and holistic approaches. The Delphi method allows for reliable, expert-driven decisions through anonymous feedback rounds. CI not only addresses diagnosis and treatment planning challenges but also improves resource allocation. While these approaches can reduce individual biases and systematic errors, challenges such as conformity bias and groupthink were also acknowledged.

Conclusion: This review highlights the significance of diverse expert opinions and structured consensus-building in advancing collective intelligence in oral healthcare. It emphasizes CI's potential to improve patient management through collaborative decision-making models. However, further research is necessary to explore CI's specific applications and effectiveness in oral healthcare.

目的:诊断和治疗错误是有害的,但相对普遍的初级卫生保健设置。以同伴意见和集体决策为形式的众包和集体智慧(CI)可以导致牙医对诊断和治疗计划的修改。本文综述了它们在口腔保健中的应用,探讨了它们在口腔保健中的具体应用,并评价了它们在口腔保健中的优缺点。方法:考虑到本课题的复杂性,选择范围综述方法作为最佳研究设计。使用选定的搜索词和搜索策略在Medline、Scopus、Web of Science、SciELO、LILACS和CINAHL六个数据库中实现了从1980年到2024年12月的文献检索。纳入标准指定了以英语、西班牙语和葡萄牙语发表的研究,重点关注CI在口腔保健机构中的应用。结果:在265项鉴定的研究中,筛选了63篇摘要和20篇全文研究,7项研究被纳入定性综合。研究结果表明,CI可以通过采用各种群体决策模型,如多学科团队(MDTs)和德尔菲法,显著提高初级卫生保健机构的患者管理。mdt由来自不同学科的专业人员组成,可以通过协作解决问题和整体方法来改善患者护理。德尔菲方法允许通过匿名反馈轮进行可靠的、专家驱动的决策。CI不仅解决了诊断和治疗计划的挑战,而且改善了资源分配。虽然这些方法可以减少个人偏见和系统错误,但也承认了从众偏见和群体思维等挑战。结论:本综述强调了多样化的专家意见和结构化共识的建立对促进口腔保健集体智慧的重要性。它强调CI通过协作决策模型改善患者管理的潜力。然而,CI在口腔保健中的具体应用和效果有待进一步研究。
{"title":"A scoping review of crowdsourcing and collective intelligence in oral healthcare.","authors":"Rodrigo J Mariño, Max Ganhewa, Alison Lau, Randal von Marttens, Nicola Cirillo","doi":"10.1186/s12903-026-07670-7","DOIUrl":"https://doi.org/10.1186/s12903-026-07670-7","url":null,"abstract":"<p><strong>Objective: </strong>Diagnostic and treatment errors are detrimental yet relatively common in primary healthcare settings. Crowdsourcing and collective intelligence (CI) in the form of peers' opinion and group decision-making can lead to modifications in diagnosis and treatment planning by dentists. In this review, it was explored their use in oral healthcare delivery, investigating specific applications and evaluating their merits and drawbacks in oral healthcare.</p><p><strong>Methods: </strong>A scoping review approach was chosen as the optimal study design, due to the complexity of the topic. A literature search from 1980 to December 2024 using selected search terms and a search strategy was implemented across six databases: Medline, Scopus, Web of Science, SciELO, LILACS, and CINAHL. Inclusion criteria specified studies published in English, Spanish, and Portuguese, focusing on CI applications in oral healthcare settings.</p><p><strong>Results: </strong>Of the 265 identified studies, 63 abstracts and 20 full-text studies were screened, and 7 studies were included in the qualitative synthesis. The findings suggest that CI may significantly enhance patient management in primary healthcare settings by employing various group decision-making models such as multidisciplinary teams (MDTs) and the Delphi method. MDTs, comprising professionals from different disciplines, can enhance patient care through collaborative problem-solving and holistic approaches. The Delphi method allows for reliable, expert-driven decisions through anonymous feedback rounds. CI not only addresses diagnosis and treatment planning challenges but also improves resource allocation. While these approaches can reduce individual biases and systematic errors, challenges such as conformity bias and groupthink were also acknowledged.</p><p><strong>Conclusion: </strong>This review highlights the significance of diverse expert opinions and structured consensus-building in advancing collective intelligence in oral healthcare. It emphasizes CI's potential to improve patient management through collaborative decision-making models. However, further research is necessary to explore CI's specific applications and effectiveness in oral healthcare.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145965417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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BMC Oral Health
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