BMC Oral Health最新文献

Purpose: The aim of this study was to compare the shear bond strengths of four distinct CAD/CAM restorative materials using conventional resin-based adhesive cement and self-adhesive resin cement.

Materials and methods: Specimens (14 mm × 18 mm × 2 mm) were obtained for each restorative material: IPS e.max CAD (Ivoclar Vivadent (LEICHTENSTEIN), GC Cerasmart (GC-Corp. JAPAN), Vita-Enamic (Vita-ZahnFabrik, GERMANY), and Cerec Blocks (Dentsply Sirona, USA) (n = 12). Ceramic surfaces were applided with both conventional resin-based adhesive cement (LF) (GC-LinkFORCE, GC Corp., JAPAN) and self-adhesive resin cements (CO) (G-Cem One, GC Corp., JAPAN). The shear bond strength test of 96 specimens were calculated and other 96 specimens were measured this test following thermal cycles (10000 thermal cycles at 5-55 ^oC (SD Mechatronik THERMOCYCLR, Gmbh). Shear bond strength results were statistically analyzed by independent samples t test, one-way ANOVA, two-way ANOVA, four-way ANOVA and for one and all test Post Hoc Tukey HSD test.

Results: After thermal cycles, a significant difference was observed between the shear bond strength of LF and CO cements to all ceramics except IPS e.max CAD ceramic (p < 0.05). After thermal cycling, LF cement had the strongest shear bond strength values with GC Cerasmart and the weakest bond values with Vita Enamic. CO cement had the strongest shear bond values with Cerec Blocks ceramics and the weakest bond values with GC Cerasmart. Cohesive type fractures were the most prevalent and adhesive type fractures were the least frequent both before and after thermal cycle. The type of material had a significant effect on the type of fracture after thermal cycle application (p < 0.05).

Conclusions: Thermal cycle application caused a decrease in the shear bond strength values of two kind of resin cements to all ceramics. It can be concluded that self-adhesive composite resin cement (G-CemONE) are suitable for leucite-reinforced glass-ceramic and lithium disilicate ceramics, and conventional resin-based adhesive cement (GC-LinkFORCE) is suitable for resin nanoceramic material and polymer-infiltrated glass-ceramic material types.

Background: To investigate the geometric characteristics of the danger zone in the mesial roots of mandibular molars using micro-computed tomography (micro-CT).

Methods: A total of 75 extracted mandibular first (50 were 2-rooted [2RM1] and 25 were 3-rooted [3RM1]) and 35 2-rooted mandibular second molars (2RM2) were collected and evaluated using micro-CT. The morphological aspects of the mesial roots associated with the danger zone (the canal curvature, minimum mesial [MWT] and distal canal wall thickness [DWT], depth and level of root concavities) were evaluated. One-way analysis of variance (ANOVA) was used for multiple group comparisons. Student's t-test or paired t-test was used to test the means between two groups.

Results: All mesial roots curved severely (81.8%, 90/110) or moderately (18.2%, 20/110) towards the furcation side, and the mean angle was 25.3 ± 7.2 degrees. The presence of a distolingual root only had limited influence on the geometricgeometry of the mesial root. In the majority of cases, the mean DWT was less than the MWT, and statistical significance (all p < 0.05) was detected at 0-3 mm (MB and ML of 3RM1), 0-4 mm (MB of 2RM1, and MB and ML of 2RM2), 0-5 mm (single mesial canals of mandibular first and second molars), and 0-6 mm (ML of 2RM1) below furcation. The mean depth of distal concavities is always greater (all p < 0.05) than the mesial ones at each root level. Generally, the mean depth of distal concavities increased apically in the cervical portion, reaching the maximum value at 2 mm below furcation, and then declined gradually in the apical portion.

Conclusions: The mesial roots of mandibular first and second molars often exhibit severe distal curvature, with a mean Schneider's angle of 25.3 degrees, and the thinnest dentin wall is typically on the distal side. Distal root concavities are significantly deeper than mesial ones, with the maximum depth generally located 2 mm below the furcation. When identifying the danger zone, factors such as DWT should not be considered in isolation. Canal curvature, distal root concavities, and the type of instrument used are also critical in affecting the likelihood and location of strip perforation, though their precise roles warrant further investigations.

Background: Periodontitis is a chronic inflammatory disease that seriously affects the quality of patients' life. Diabetes mellitus (DM) is the independent risk factor of periodontitis. The association between vitamin B₆ with several inflammatory diseases have been reported in previous studies. However, the effect of vitamin B₆ on the association of T2DM and periodontitis remains unclear. This study aimed to explore the effect of vitamin B₆ [evaluated by serum pyridoxal 5'-phosphate (PLP)] on the association of T2DM and periodontitis in American population.

Methods: Data of this cross-sectional study were extracted from the National Health and Nutrients Examination Survey (NHANES) 2009-2010. Serum PLP level was the indicator of vitamin B₆ status in vivo and measured by enzymatic assay. Covariates included demographic information, physical examination, lifestyle characteristics, laboratory parameters and complications. The weighted univariate and multivariate logistics regression models were conducted to explore the association of PLP, T2DM and periodontitis, with the odds ratios (ORs) and 95% confidence intervals (CIs). Subgroup analyses were further performed to explore these associations based on age, body mass index (BMI), cardiovascular disease (CVD) and dental decay.

Results: Finally, 3,491 eligible adults with the information of periodontitis measurement, T2DM diagnosis and PLP detection were included. Among them, 1,999 (57.26%) had periodontitis. After adjusted confounders, we found adults with T2DM had high odds of periodontitis (OR = 1.45, 95%CI: 1.04-2.02); while no significant association between PLP and periodontitis was observed. Adults with low PLP level (< 67.20 nmol/L) and combined with T2DM had high odds of periodontitis (OR = 1.82, 95%CI: 1.29-2.55), no significant association was found between T2DM and periodontitis in adults with high PLP level (≥ 67.20 nmol/L). These results suggested that serum PLP levels may have the modulatory effect on the association of T2DM and periodontitis. This modulatory effect remains robust in subgroup analysis, especially in adults aged ≥ 60 years (OR = 4.54, 95%CI: 2.15-9.62), with obese (OR = 3.06, 95%CI: 1.31-7.18), without the history of CVD (OR = 2.25, 95%CI: 1.06-4.79) and without dental decay (OR = 2.93, 95%CI: 1.51-5.68) (all P < 0.05).

Conclusion: Our study suggested that adults with T2DM had the high odds of periodontitis, and serum PLP may plays a modulatory effect in this association. T2DM patients maintaining a higher intake of vitamin B₆ may have potential benefits in reducing the periodontitis risk.

Objective: To explore the pain prognosis, medication efficacy and treatment willingness of patients with burning mouth syndrome (BMS) and to identify the factors influencing the pain prognosis, medication efficacy and treatment willingness of patients with BMS.

Methods: Medical records of patients who were clinically diagnosed with BMS and who complained of oral mucosal pain at the Department of Stomatology, The First Affiliated Hospital of Zhengzhou University, were retrospectively collected from January 2019 to April 2022. Telephone follow-ups were conducted in August 2024 to investigate the patients' pain prognosis, medication efficacy, willingness for treatment and related treatment information.

Results: Among the 192 patients, only 31.77% (61/192) reported complete elimination of pain; 37.50% (72/192) reported that the pain still existed but had improved, and 30.73% (59/192) reported no improvement at all. A total of 31.25% (60/192), 34.90% (67/192), and 32.81% (63/192) of the BMS patients evaluated medication efficacy as significantly effective, effective, or ineffective, respectively. Among the 131 patients who still had pain symptoms, 38.17% (50/131) intended to continue treatment. Logistic regression revealed that patients who were older (P = 0.023), who had visited multiple hospitals for treatment (P = 0.001), who were afraid of cancer (P = 0.011) and who were prone to anxiety or depression (P < 0.001) had poorer pain improvement. Patients who had visited multiple hospitals (P < 0.001) and those who were prone to anxiety or depression (P < 0.001) had significantly lower evaluations of medication efficacy. Males (P = 0.041) and those who had visited multiple hospitals (P < 0.001) were more willing to continue treatment.

Conclusion: The prognosis for most BMS patients tends to be relatively poor. Age, anxiety or depression, and fear of cancer may affect the pain prognosis of patients with BMS, whereas psychological factors may also impact the efficacy of medication.

Objectives: To quantify longitudinal bone changes in the maxilla after secondary alveolar bone grafting (SABG) in patients with unilateral cleft lip and/or cleft palate (CL/P), and to describe the maxillary dimensions before and after SABG in all orthogonal planes using a Cone Beam Computed Tomography (CBCT)-based methodology.

Methods: Ethical approval was obtained to retrospectively analyze CBCT scans of children treated for unilateral alveolar clefts. Inclusion criteria encompassed individuals who underwent SABG before the eruption of the cleft-side permanent lateral incisor or, if absent, the permanent ca-nine, and had both preoperative and postoperative CBCT scans. A total of seven measurements of maxillary dimensions in all orthogonal planes, as well as in panoramic reconstruction, were conducted in the CBCT images. The normality of the data was confirmed with the Shapiro-Wilk test. A paired t-test was applied to assess significant differences between the preoperative and postoperative measurements (p < 0.05). The impact of age, gender, and their interrelation was evaluated by two-way ANOVA (p < 0.05).

Results: A total of 47 patients, comprising 32 males and 15 females, were selected based on the specified criteria. Notably, we observed a significant increase in sagittal, vertical, and transverse dimensions between the preoperative scans and those taken one year postoperatively (p < 0.05), irrespective of the patients' ages and genders. When considering gender, data indicated that male patients exhibited wider transverse dimensions in both the preoperative and postoperative measurements.

Conclusions: This study introduced a CBCT-based method to quantitatively assess maxillary changes in unilateral CL/P patients after SABG. The approach demonstrated continuous dimensional changes in all orthogonal planes. In addition, it described the maxillae dimensions in all planes. Future research can utilize this method for precise measurement of maxillary alterations and dimensions.

Background: Identifying fractured endodontic instruments (FEIs) in periapical radiographs (PAs) is a critical yet challenging aspect of root canal treatment (RCT) due to anatomical complexities and overlapping structures. Deep learning (DL) models offer potential solutions, yet their comparative performance in this domain remains underexplored.

Methods: A dataset of 700 annotated PAs, including 381 teeth with FEIs, was divided into training, validation, and test sets (60/20/20 split). Five DL models-DenseNet201, EfficientNet B0, ResNet-18, VGG-19, and MaxVit-T-were trained using transfer learning and data augmentation techniques. Performance was evaluated using accuracy, AUC and MCC. Statistical analysis included the Friedman test with post-hoc corrections.

Results: DenseNet201 achieved the highest AUC (0.900) and MCC (0.810), outperforming other models in FEI detection. ResNet-18 demonstrated robust results, while EfficientNet B0 and VGG-19 provided moderate performance. MaxVit-T underperformed, with metrics near random guessing. Statistical analysis revealed significant differences among models (p < 0.05), but pairwise comparisons were not significant.

Conclusions: DenseNet201's superior performance highlights its clinical potential for FEI detection, while ResNet-18 offers a balance between accuracy and computational efficiency. The findings highlight the need for model-task alignment and optimization in medical imaging applications.

Background: Thyroid dysfunction causes various oral manifestations, while periodontal disease is a chronic inflammatory condition affecting the supporting structures of teeth. This systematic review and meta-analysis aimed to evaluate the effects of thyroid dysfunction on periodontal disease indices, synthesizing evidence to clarify the relationship between these conditions.

Methods: A comprehensive search followed PRISMA guidelines across Medline, Scopus, Web of Science, and Google Scholar from inception to September 2024. Studies included adults with diagnosed thyroid dysfunction and healthy controls. Data were extracted on thyroid function tests and periodontal disease indices. The risk of bias and quality of studies were assessed using funnel plots, Begg's and Egger's indices, and the Cochrane tool. Effect sizes were calculated using standard mean difference (SMD) via Comprehensive Meta-Analysis software.

Results: Eight studies (seven publications) were included. The analysis revealed that patients with thyroid dysfunction exhibited significantly higher periodontal disease indices than controls, with a pooled SMD of 0.369 (95% CI: 0.194-0.545, p < 0.001). The effects of thyroid dysfunction were found on clinical attachment level and pocket probing depth, but not on other indices like the gingival and plaque indexes. Sensitivity analysis confirmed the robustness of these findings. The quality of studies was low, with notable risks of bias.

Conclusions: Thyroid dysfunction is associated with increased periodontal disease indices, highlighting the need for further research to explore the underlying mechanisms and improve clinical management strategies for affected patients. Future studies should aim for higher methodological rigor to enhance the reliability of findings.

This case report describes orthodontic treatment of an adult female with severe skeletal Class II malocclusion on a Class II skeletal base complicated by deficient chin, condylar resorption and anterior open bite (The IOFTN score = 4.4, ANB °=11.3, SN-MP °=58.2). Treatment carried out with 4 1st premolar extractions and using two mini-implants (diameter: 1.6 mm; length: 10 mm; Cibei Medical Instruments, Ningbo, China) that were inserted between the maxillary first molar and second premolar to intrude the bilateral maxillary first molars using elastic traction. Alveolar bone dehiscences were detected on the palatal or lingual side of the anterior teeth roots after orthodontic camouflage treatment. During the 3-year follow-up period, acceptable periodontal health and favourable alveolar bone modeling of maxillary and mandibular anterior teeth were detected. No further lesions developed in the condyle during the treatment period. This case confirmed that the capacity of palatal or lingual alveolar bone remodeling, which might be greater than previously believed, but the specific mechanism is still unclear.

Background: Identifying the dental caries risk factors helps plan interventions. This scoping review mapped the existing literature on dental caries risk indicators for children, adolescents, and adults in Nigeria. It elucidated the commonalities and differences in these populations' behavioral, biological, and social risk indicators, and identified the local government areas in Nigeria where information on dental caries risk indicators are missing.

Methods: A search of the literature search was performed in July 2023 in PubMed, African Journal Online, Google Scholar, and Cochrane Library [CENTRAL] using a combination of keywords related to dental caries, risk factors, early childhood, children, adults, and Nigeria. Only peer-reviewed full-length articles on risk factors for dental caries in Nigeria published in English were included. Descriptive statistics were used to summarize the study's characteristics and risk indicators for dental caries. The risk indicators for dental caries were categorized into behavioral, biological, and social. Differences and commonalities of the identified behavioral, biological, and social risk indicators for the three populations were identified.

Results: After screening 570 studies, 27 publications for preschoolers, 37 for school children/adolescents, and 17 for adults met the inclusion criteria. For all groups, key social risk indicators were age, gender, socioeconomic, and educational status, biological risk indicators were anthropometric measurements and bacterial counts, and behavioral risks indicators were toothbrushing, snacking, and oral hygiene. Peculiar behavioral, biological, and social risk indicators were identified for each age group. Most studies are clustered in southern Nigeria. In addition, studies in preschoolers was skew to southwestern Nigeria, that of children/adolescents were skewed to Ife Central LGA in Osun State, while that for adults were skewed to Egor LGA in Edo State. Furthermore, participants recruitment was most diverse in Lagos State.

Conclusions: The shared risk indicators for dental caries can facilitate the development of overarching caries prevention program for the difference age groups in Nigeria. while the age specific risk indicators can inform the development of population specific interventions. This scoping review underscores the importance of a holistic, life course approach to dental caries risk management.

Background: This study aimed to evaluate the long-term color stability of single-shade composite resins when exposed to simulated intraoral conditions, including staining, brushing, and thermal cycling. Additionally, the study compared the performance of spectrophotometry and cross-polarized (CP) photography in detecting color changes, focusing on their applicability for both clinical and research purposes.

Materials and methods: The study employed five single-shade composite resins (Omnichroma; OMN, Zenchroma; ZNC, Vittra APS Unique; VTR, Charisma One; CHR, and Essentia Universal; ESU) and one multi-shade composite resin (Filtek Z550: FLT) for testing. The specimens were subjected to thermal cycling, staining, and brushing to simulate intraoral conditions. Color measurements were conducted using a spectrophotometer and CP photography at the initial baseline (t₀) and following each subsequent procedure 10-day (t₁) and 1-year simulated staining, brushing and thermal cycling (t₂). Color differences (ΔE₁, ΔE₂) were calculated using the CIEDE2000 formula. Statistical analyses included Shapiro-Wilk for normality, ANOVA and paired t-tests for parametric data, and Kruskal-Wallis and Wilcoxon tests for non-parametric data. Method consistency was evaluated with the Intra-Class Correlation Coefficient (ICC) (p < 0.05).

Results: All composite groups demonstrated statistically significant color changes following the simulated conditions (p < 0.001). The CHR group exhibited the highest values for both ΔE₁ and ΔE₂, indicating the greatest degree of discoloration. The FLT and ZNC groups exhibited the lowest ΔE values across methods at various time points. A positive correlation was identified between spectrophotometer and CP photography measurements for all parameters (p < 0.001), although the correlation for ΔE₁ and ΔE₂ was less robust.

Conclusions: Single-shade composites display a high susceptibility to significant discoloration when subjected to simulated intraoral conditions, with CHR exhibiting the most pronounced alterations. Both spectrophotometry and CP photography were effective in assessing color stability, with CP photography offering a practical alternative for clinical settings. These findings offer insight into the aesthetic durability of single-shade composites and underscore the importance of long-term evaluations.