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Minor salivary flow as a diagnostic tool for screening hyposalivation in Medication-Induced Xerostomia. 少量唾液流动作为筛选药物性口干性唾液分泌不足的诊断工具。
IF 3.1 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-02-05 DOI: 10.1186/s12903-026-07798-6
Sanjana Santhosh Kumar, Genevieve Arany-Lao-Kan, Xiuhui Xu, Abdel Hameed Mahmoud, Fabio Campanelli Massarotto, Victoria Thomas, Abdul Basir Barmak, Szilvia Arany

Background: We aimed to determine whether minor salivary flow (MSF) rate, measured via a rapid paper-based test, can serve as a reliable screening tool for detecting hyposalivation. This study, conducted in a real-world clinical setting, evaluated the diagnostic performance of MSF against unstimulated whole saliva (UWS) as the reference standard in individuals experiencing xerostomia due to medications.

Methods: We conducted a cross-sectional study of 135 adults aged 45-64 years with xerostomia and ongoing anticholinergic medication use. MSF was measured using a one-minute Shrimer strip placed in the upper labial vestibule, and reliability was assessed via triplicate measurements in a subsample (n = 40). UWS flow was used as the reference standard for reduced (hyposalivation) saliva secretion. The diagnostic performance of MSF was analyzed using Receiver Operating Characteristic (ROC) curves, and multivariable logistic regression assessed its predictive utility after adjusting for demographic and clinical covariates.

Results: MSF demonstrated high internal consistency (Cronbach's α = 0.94) and strong inter-replicate agreement (r = 0.83-0.87). Participants with hypo ratetion had significantly lower MSF than those without (mean difference = 2.41 µL/cm²/min, p < 0.001). At an optimal MSF cutoff, sensitivity was 80.0% and specificity was 54.5% (with Area Under the Curve; AUC = 0.726). In multivariable models, MSF and xerostomia severity were independent predictors of hyposalivation, with an overall model AUC of 0.827.

Conclusion: MSF, measured using a simple, non-invasive method, is a reliable and moderately accurate screening tool for identifying hyposalivation in adults with medication-induced xerostomia. These findings support its use in clinical settings; however, further refinement and validation are necessary to establish diagnostic thresholds and determine its applicability.

背景:我们的目的是确定是否小唾液流量(MSF)率,通过快速纸基测试测量,可以作为检测低唾液的可靠筛选工具。本研究在真实世界的临床环境中进行,评估了MSF对未刺激全唾液(UWS)的诊断性能,作为药物引起的口干症患者的参考标准。方法:我们对135名年龄在45-64岁之间患有口干症并正在使用抗胆碱能药物的成年人进行了横断面研究。MSF采用放置在上唇前庭的一分钟Shrimer条测量,并通过在子样本(n = 40)中重复测量来评估可靠性。以UWS流量作为唾液分泌减少(低唾液)的参考标准。采用受试者工作特征(ROC)曲线分析MSF的诊断效果,并在调整人口统计学和临床协变量后,采用多变量logistic回归评估其预测效用。结果:MSF具有较高的内部一致性(Cronbach’s α = 0.94)和较强的重复间一致性(r = 0.83-0.87)。低剂量受试者的MSF显著低于无剂量受试者(平均差值= 2.41 μ L/cm²/min, p)。结论:MSF是一种简单、无创的方法,是一种可靠、中等准确度的筛查工具,可用于识别药物性口干症成人的低剂量。这些发现支持其在临床应用;然而,进一步的细化和验证是必要的,以建立诊断阈值和确定其适用性。
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引用次数: 0
Comparative in vitro evaluation of the mechanical behavior of implant-abutment connections for zirconia and titanium implants. 氧化锆和钛种植体-基台连接力学行为的体外比较评价。
IF 3.1 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-02-05 DOI: 10.1186/s12903-026-07855-0
Camila da Silva Resende, Lara Rúbia Marques Nascimento, Olívia Francescato, Rafaela Regina de Lima, Barbara Magalhães Figueiredo Dias, Dhelfeson Willya Douglas-de-Oliveira, Frederico Santos Lages
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引用次数: 0
Fractal dimension and cortical indices of the mandible in hypercholesterolaemia: a retrospective study. 高胆固醇血症患者下颌骨的分形维数和皮质指数的回顾性研究。
IF 3.1 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-02-05 DOI: 10.1186/s12903-026-07817-6
Dóra Iványi, Márton Kivovics, Csilla Szerencse, Orsolya Németh
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引用次数: 0
Effect of an alginate-based antacid and simulated gastric acid on the surface roughness and color stability of CAD/CAM resin-based materials. 海藻酸酯基抗酸剂和模拟胃酸对CAD/CAM树脂基材料表面粗糙度和颜色稳定性的影响。
IF 3.1 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-02-05 DOI: 10.1186/s12903-026-07844-3
Didar Dilan Hartavi, Neşe Cızıroğlu, Rafat Sasany, Muammer Alhan Babat, Seyed Ali Mosaddad
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引用次数: 0
Fibula flap versus soft tissue flap with reconstruction plate for mandibular stage 3 medication-related osteonecrosis of the jaw: a retrospective cohort study. 腓骨瓣与软组织瓣结合重建板治疗下颌骨3期药物相关性骨坏死:一项回顾性队列研究。
IF 3.1 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-02-05 DOI: 10.1186/s12903-026-07826-5
Yuhan Lin, Yihong Fang, Yongzhen Lai, Chuanqing Mao, Chengyong Wang, Meng Lu, Jin Wang, Qiming Ouyang, Weihui Chen
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引用次数: 0
Effect of attachment wear on maxillary canine rotation in clear aligner therapy: a three-dimensional finite element analysis. 明确矫正器治疗中附着磨损对上颌犬齿旋转的影响:三维有限元分析。
IF 3.1 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-02-05 DOI: 10.1186/s12903-026-07814-9
Qiuying Li, Bowen Xu, Dongyu Fang, Kai Yang

Background: This study aimed to explore the effect of attachment wear on maxillary canine rotation in clear aligner therapy through three-dimensional finite element analysis.

Methods: Finite element models, comprising the maxillary bone, periodontal ligament, upper dentition, attachments (initial and worn), and clear aligners, were created to simulate maxillary canine rotation. Two attachment types (vertical rectangular and rotation-optimized) with five wear levels (M0, M2, M4, M6, and M8) were considered for canine rotation analysis. Tooth displacement and equivalent stress in the roots and periodontal ligaments were analyzed.

Results: With increased attachment wear, both groups showed reduced canine rotation angles and lower stress levels in roots and periodontal ligaments. The most significant reduction in the canine rotation angles and stress values for the rectangular group occurred between M2 and M4, with the efficiency of canine rotation falling below 50% from M4 onward. In contrast, the optimized group experienced the most substantial decline between M6 and M8, with the efficiency of canine rotation falling below 50% at M8.

Conclusions: Attachment wear decreased maxillary canine rotation efficiency. It is preferable to use optimized rotation attachments when correcting maxillary canine rotation. After six months of optimized attachment use, if maxillary canines still require rotation, orthodontists should closely monitor attachment wear to ensure treatment effectiveness. Immediate restoration or re-bonding of the attachments is required if it is determined to be essential.

背景:本研究旨在通过三维有限元分析,探讨透明矫正器治疗中附着体磨损对上颌犬齿旋转的影响。方法:建立上颌骨、牙周韧带、上牙列、附着体(初始和磨损)、透明矫正器等有限元模型,模拟上颌犬齿旋转。考虑了5个磨损级别(M0、M2、M4、M6和M8)的两种附着类型(垂直矩形和旋转优化)进行犬齿旋转分析。分析了牙根和牙周韧带的牙位移和等效应力。结果:随着附着体磨损的增加,两组的牙根和牙周韧带的应力水平降低,牙根旋转角度降低。矩形组的犬齿旋转角度和应力值下降最显著的是在M2和M4之间,从M4开始犬齿旋转效率下降到50%以下。相比之下,优化组在M6和M8之间的下降幅度最大,在M8时犬齿旋转效率降至50%以下。结论:附着体磨损降低上颌犬齿旋转效率。在矫正上颌犬齿旋转时,优选使用优化的旋转附着体。经过优化的附着体使用6个月后,如果上颌犬仍需要旋转,正畸医师应密切监测附着体磨损情况,以确保治疗效果。如果确定必须立即恢复或重新粘合附件,则需要立即恢复或重新粘合附件。
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引用次数: 0
The state of knowledge of Polish teachers about oral health and methods of preventing dental caries in children - a sociomedical survey. 波兰教师关于口腔健康和预防儿童龋齿方法的知识状况——一项社会医学调查。
IF 3.1 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-02-05 DOI: 10.1186/s12903-026-07854-1
Angelika Kobylińska, Dariusz Gozdowski, Dorota Olczak-Kowalczyk
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引用次数: 0
A comparative evaluation of two large language models in pediatric dentistry. 儿童牙科两种大型语言模型的比较评价。
IF 3.1 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-02-05 DOI: 10.1186/s12903-026-07810-z
Taibe Tokgöz Kaplan
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引用次数: 0
Marginal and internal adaptation of esthetic crowns for primary molars: an in-vitro study. 初生磨牙美观冠边缘和内部适应的体外研究。
IF 3.1 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-02-05 DOI: 10.1186/s12903-026-07686-z
Abla Arafa, Mohamed Fattouh
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引用次数: 0
Three-dimensional assessment of condylar head position in CBCT scans before and after orthognathic surgery. 正颌手术前后CBCT扫描中髁突头位置的三维评估。
IF 3.1 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-02-04 DOI: 10.1186/s12903-026-07720-0
Kristina Schultze-Mosgau, Sebastian Gubik, Theresia Herterich, Andreas Vollmer, Niko Breitenbuecher, Hartmut Böhm, Alexander Kübler, Felix Kunz, Stefan Hartmann

Background: Recent advances in orthognathic surgery-particularly the adoption of virtual 3D planning and patient-specific 3D-printed splints-have improved surgical precision, reduced operative time, and enhanced predictability of outcomes. Despite these developments, accurate intraoperative positioning of the mandibular condyle, especially the condylar head, during bilateral sagittal split osteotomy (BSSO), remains a major challenge. Although multiple techniques for condylar positioning have been proposed, their impact on postoperative condylar head position and joint space morphology has not been comprehensively assessed. This study aimed to evaluate postoperative changes in condylar head position and temporomandibular joint (TMJ) space using a Procrustes algorithm, and to investigate potential effects of surgeon handedness.

Methods: A retrospective cone beam computed tomography (CBCT) analysis was conducted on 40 patients (24 female, 16 male) who underwent orthognathic surgery. The cohort comprised 27 patients with Angle Class II and 13 with Angle Class III malocclusion. Eighteen patients underwent bimaxillary procedures, and 22 underwent monomaxillary osteotomies. Condylar position and joint space dimensions were measured, and Procrustes shape analysis was applied to quantify TMJ space deformation. Statistical tests assessed positional changes and correlations with skeletal class, displacement, and surgeon handedness.

Results: Significant postoperative changes were observed, with a bilateral reduction in cranial distances, reflecting a more caudal condylar head position, and a significant widening of the cranial joint space on the right side. Procrustes analysis confirmed measurable deformation of anterior and posterior TMJ compartments. Condylar heads were frequently positioned dorsally during initial registration, and results suggest that surgeon handedness may systematically influence condylar positioning.

Conclusions: Postoperative condylar head position and TMJ space morphology are influenced by intraoperative handling, with surgeon handedness emerging as a potential contributor. Incorporating shape analysis methods such as Procrustes algorithms into future digital workflows may improve condylar positioning strategies and enhance surgical outcomes in BSSO.

背景:正颌手术的最新进展,特别是虚拟3D计划和患者特异性3D打印夹板的采用,提高了手术精度,缩短了手术时间,增强了结果的可预测性。尽管有这些进展,在双侧矢状面劈开截骨术(BSSO)中,准确定位下颌髁,特别是髁头的术中定位仍然是一个主要的挑战。虽然已经提出了多种髁突定位技术,但它们对术后髁突头位置和关节间隙形态的影响尚未得到全面评估。本研究旨在使用Procrustes算法评估术后髁头位置和颞下颌关节(TMJ)间隙的变化,并探讨外科医生利手性的潜在影响。方法:对40例正颌手术患者(女24例,男16例)进行回顾性锥形束计算机断层扫描(CBCT)分析。该队列包括27例Angle II型和13例Angle III型错牙合。18例患者行双颌截骨,22例行单颌截骨。测量髁突位置和关节空间尺寸,应用Procrustes形状分析量化TMJ空间变形。统计测试评估了位置变化及其与骨骼类别、位移和外科医生惯用手的相关性。结果:术后观察到明显的变化,双侧颅骨距离缩小,反映了更尾端的髁头位置,右侧颅骨关节间隙明显变宽。前列腺分析证实TMJ前后腔室可测量变形。在初次注册时,髁头经常被定位于背侧,结果表明外科医生的惯用手可能会系统性地影响髁的定位。结论:术后髁头位置和TMJ空间形态受术中处理的影响,外科医生的利手性可能是一个潜在的影响因素。将Procrustes算法等形状分析方法整合到未来的数字工作流程中,可能会改善BSSO的髁突定位策略并提高手术效果。
{"title":"Three-dimensional assessment of condylar head position in CBCT scans before and after orthognathic surgery.","authors":"Kristina Schultze-Mosgau, Sebastian Gubik, Theresia Herterich, Andreas Vollmer, Niko Breitenbuecher, Hartmut Böhm, Alexander Kübler, Felix Kunz, Stefan Hartmann","doi":"10.1186/s12903-026-07720-0","DOIUrl":"https://doi.org/10.1186/s12903-026-07720-0","url":null,"abstract":"<p><strong>Background: </strong>Recent advances in orthognathic surgery-particularly the adoption of virtual 3D planning and patient-specific 3D-printed splints-have improved surgical precision, reduced operative time, and enhanced predictability of outcomes. Despite these developments, accurate intraoperative positioning of the mandibular condyle, especially the condylar head, during bilateral sagittal split osteotomy (BSSO), remains a major challenge. Although multiple techniques for condylar positioning have been proposed, their impact on postoperative condylar head position and joint space morphology has not been comprehensively assessed. This study aimed to evaluate postoperative changes in condylar head position and temporomandibular joint (TMJ) space using a Procrustes algorithm, and to investigate potential effects of surgeon handedness.</p><p><strong>Methods: </strong>A retrospective cone beam computed tomography (CBCT) analysis was conducted on 40 patients (24 female, 16 male) who underwent orthognathic surgery. The cohort comprised 27 patients with Angle Class II and 13 with Angle Class III malocclusion. Eighteen patients underwent bimaxillary procedures, and 22 underwent monomaxillary osteotomies. Condylar position and joint space dimensions were measured, and Procrustes shape analysis was applied to quantify TMJ space deformation. Statistical tests assessed positional changes and correlations with skeletal class, displacement, and surgeon handedness.</p><p><strong>Results: </strong>Significant postoperative changes were observed, with a bilateral reduction in cranial distances, reflecting a more caudal condylar head position, and a significant widening of the cranial joint space on the right side. Procrustes analysis confirmed measurable deformation of anterior and posterior TMJ compartments. Condylar heads were frequently positioned dorsally during initial registration, and results suggest that surgeon handedness may systematically influence condylar positioning.</p><p><strong>Conclusions: </strong>Postoperative condylar head position and TMJ space morphology are influenced by intraoperative handling, with surgeon handedness emerging as a potential contributor. Incorporating shape analysis methods such as Procrustes algorithms into future digital workflows may improve condylar positioning strategies and enhance surgical outcomes in BSSO.</p>","PeriodicalId":9072,"journal":{"name":"BMC Oral Health","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146117794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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BMC Oral Health
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