Pot experiment was conducted to evaluate the impact of exogenous foliar spray of GB on vegetative growth and some biochemical aspects of fenugreek (Trigonella foenum-graecum L.) in the presence of salt. GB was applied to four concentrations (0, 25, 50, and 75 mM) under salt concentration, 150 mM NaCl in addition to the control. salt stress decreases all the growth parameters and negatively affects photosynthetic pigments as well as relative water content and protein. However, the foliar spray of GB increases these parameters, especially at a concentration of 50 mM. Regarding carbohydrates, total phenolics, flavonoids and antioxidant activity increased under salt stress compared to control also GB foliar spray induced the accumulation of them. Moreover, these parameters increase by increasing the concentration of GB. More than others, GB reduces the entry of deleterious ions (Na+ and Cl-), in contrast, boosts the accumulation of Ca2+ and K+. These results suggest that foliar spray of GB can enhance the growth and tolerance of fenugreek under saline conditions.
通过盆栽试验，研究了盐胁迫下外源GB叶面喷施对葫芦巴营养生长及部分生化指标的影响。在盐浓度为0、25、50、75 mM的4种浓度下，在对照的基础上，分别施用150 mM NaCl。盐胁迫降低了所有生长参数，并对光合色素、相对含水量和蛋白质含量产生负面影响。在盐胁迫下，叶面喷施GB使这些参数增加，特别是在浓度为50 mM时。在碳水化合物、总酚类物质、总黄酮和抗氧化活性方面，叶面喷施GB使其积累明显高于对照。而且，这些参数随着GB浓度的增加而增加。相比之下，GB减少了有害离子(Na+和Cl-)的进入，相反，促进了Ca2+和K+的积累。综上所述，叶面喷施GB能促进胡芦巴在生理盐水条件下的生长和耐受性。
{"title":"Glycine betaine enhancing plant growth and antioxidant activity of fenugreek (Trigonella foenum-graecum L.) under salt stress","authors":"Shimaa A. Ismaiel, Nagwa El-Bialy","doi":"10.4081/jbr.2022.10474","DOIUrl":"https://doi.org/10.4081/jbr.2022.10474","url":null,"abstract":"Pot experiment was conducted to evaluate the impact of exogenous foliar spray of GB on vegetative growth and some biochemical aspects of fenugreek (Trigonella foenum-graecum L.) in the presence of salt. GB was applied to four concentrations (0, 25, 50, and 75 mM) under salt concentration, 150 mM NaCl in addition to the control. salt stress decreases all the growth parameters and negatively affects photosynthetic pigments as well as relative water content and protein. However, the foliar spray of GB increases these parameters, especially at a concentration of 50 mM. Regarding carbohydrates, total phenolics, flavonoids and antioxidant activity increased under salt stress compared to control also GB foliar spray induced the accumulation of them. Moreover, these parameters increase by increasing the concentration of GB. More than others, GB reduces the entry of deleterious ions (Na+ and Cl-), in contrast, boosts the accumulation of Ca2+ and K+. These results suggest that foliar spray of GB can enhance the growth and tolerance of fenugreek under saline conditions.","PeriodicalId":9116,"journal":{"name":"Bollettino della Societa italiana di biologia sperimentale","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81187210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mahdiyeh Javaherian, R. Bakhtiari, Hatef Ajoudanifar, S. Shokri, A. Mirzaie
Numerous commensal microorganisms live on human skin and play an important role in human health. Any type of abnormality in the skin microbiome can result in skin damage and various diseases. Skin disorders such as atopic dermatitis and psoriasis are common skin complications caused by an imbalance of skin microorganisms. Probiotics are live microorganisms that, when consumed in sufficient quantities, can benefit human health. Using probiotics to treat various skin complications has gained popularity in recent years. Probiotics have proven to be a promising agent for improving skin health and condition, with the potential to reduce skin pathogens and boost skin immunity through antimicrobial agent production and nutrient competition. The rising incidence of skin cancer, particularly melanoma, over the last four decades emphasizes this point. The link between skin microbiota imbalance and skin cancer, particularly Non-Melanoma Skin Cancer (NMSC) and melanoma, is becoming clearer. As a result, based on the proven ability of probiotics to improve skin health. The use of microorganisms such as probiotics as a supplement in conjunction with immunotherapy has gained popularity. The purpose of this review is to discuss the relationship between microbiota imbalance and skin cancer, as well as the use of probiotics in cancer treatment.
{"title":"Microbiota, probiotics and common skin cancer: Association and therapeutic application","authors":"Mahdiyeh Javaherian, R. Bakhtiari, Hatef Ajoudanifar, S. Shokri, A. Mirzaie","doi":"10.4081/jbr.2022.10594","DOIUrl":"https://doi.org/10.4081/jbr.2022.10594","url":null,"abstract":"Numerous commensal microorganisms live on human skin and play an important role in human health. Any type of abnormality in the skin microbiome can result in skin damage and various diseases. Skin disorders such as atopic dermatitis and psoriasis are common skin complications caused by an imbalance of skin microorganisms. Probiotics are live microorganisms that, when consumed in sufficient quantities, can benefit human health. Using probiotics to treat various skin complications has gained popularity in recent years. Probiotics have proven to be a promising agent for improving skin health and condition, with the potential to reduce skin pathogens and boost skin immunity through antimicrobial agent production and nutrient competition. The rising incidence of skin cancer, particularly melanoma, over the last four decades emphasizes this point. The link between skin microbiota imbalance and skin cancer, particularly Non-Melanoma Skin Cancer (NMSC) and melanoma, is becoming clearer. As a result, based on the proven ability of probiotics to improve skin health. The use of microorganisms such as probiotics as a supplement in conjunction with immunotherapy has gained popularity. The purpose of this review is to discuss the relationship between microbiota imbalance and skin cancer, as well as the use of probiotics in cancer treatment.","PeriodicalId":9116,"journal":{"name":"Bollettino della Societa italiana di biologia sperimentale","volume":"23 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91482592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study aims to investigate the plausible inhibitory capacity of Matricaria pubescens methanolic extract (EMMP) on key diabetes-related enzymes in diabetic rats. A significant increase in the serum and pancreatic α-amylase activity in untreated diabetic rats (Diab) by 61% and 75% respectively produced a remarkable rise in blood glucose levels of 184% compared with the controls. However, the treatment of diabetic rats with the extract (Diab + EMMP) caused a significant decrease in pancreatic α-amylase activity in the pancreas (15%) and in serum (28%) compared to untreated diabetic rats. Therefore, a considerable reduction in blood sugar level has been observed reaching 28%. A significant decrease was observed in the glycated hemoglobin (HbA1c) level (28%) in rats treated with EMMP compared to untreated diabetics. Furthermore a significant increase in the pancreatic serum lipase activity (59%) compared to the control group, led to a distinguished inhibition (21%) in diabetic rats treated with EMMP. A potent protective action of β-cells was observed in diabetic rats treated with EMMP. However, we observed recovery in body weight in the diabetic rats treated with EMMP.
{"title":"The protective effect of Matricaria pubescens extracts against alloxan-induced hyperglycemia in rats","authors":"Kherraz Khaled, Ghemam Amara Djilani, Laoudj Hacen, M. Mohmed, Chefrour Azedinne","doi":"10.4081/jbr.2022.10441","DOIUrl":"https://doi.org/10.4081/jbr.2022.10441","url":null,"abstract":"This study aims to investigate the plausible inhibitory capacity of Matricaria pubescens methanolic extract (EMMP) on key diabetes-related enzymes in diabetic rats. A significant increase in the serum and pancreatic α-amylase activity in untreated diabetic rats (Diab) by 61% and 75% respectively produced a remarkable rise in blood glucose levels of 184% compared with the controls. However, the treatment of diabetic rats with the extract (Diab + EMMP) caused a significant decrease in pancreatic α-amylase activity in the pancreas (15%) and in serum (28%) compared to untreated diabetic rats. Therefore, a considerable reduction in blood sugar level has been observed reaching 28%. A significant decrease was observed in the glycated hemoglobin (HbA1c) level (28%) in rats treated with EMMP compared to untreated diabetics. Furthermore a significant increase in the pancreatic serum lipase activity (59%) compared to the control group, led to a distinguished inhibition (21%) in diabetic rats treated with EMMP. A potent protective action of β-cells was observed in diabetic rats treated with EMMP. However, we observed recovery in body weight in the diabetic rats treated with EMMP.","PeriodicalId":9116,"journal":{"name":"Bollettino della Societa italiana di biologia sperimentale","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85114736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Bonello, L. Carpi, L. Mucerino, M. Grillo, M. Ferrari
Climate change represents one of the major drivers of habitat modification that is affecting a wide variety of environments. In coastal environments, great effort is being put in trying to understand and forecast the possible effects of such processes, and the Sea-Level Rise (SLR) is one of the most investigated phenomena. This paper describes the possible effects of different 2100 sea-level scenarios related to greenhouse gas mitigation policies (Representative Concentration Pathways - RCPs). This work was conducted on a supralittoral habitat situated in Genova (Ligurian Sea), and has covered an eventual change of environmental conditions driven by SLR, which might impact the Culicid Acartomyiamariae, a resident species. The wave run-up stemming from the different RCPs was simulated using the XBeach model, and to infer SLR effects on A. mariae life cycle; the results were coupled with data obtained from field surveys. The model outputs highlighted a variation in the wave run-up oscillations under common wave conditions, which might affect the supralittoral area in terms of water input and hydric balance, and the A. mariae life cycle, which is highly dependent on temperature and salinity.
{"title":"Sea-level change and the supralittoral environment: Potential impact on a splashpool habitat on the Ligurian coast (NW Mediterranean)","authors":"G. Bonello, L. Carpi, L. Mucerino, M. Grillo, M. Ferrari","doi":"10.4081/jbr.2022.10485","DOIUrl":"https://doi.org/10.4081/jbr.2022.10485","url":null,"abstract":"Climate change represents one of the major drivers of habitat modification that is affecting a wide variety of environments. In coastal environments, great effort is being put in trying to understand and forecast the possible effects of such processes, and the Sea-Level Rise (SLR) is one of the most investigated phenomena. This paper describes the possible effects of different 2100 sea-level scenarios related to greenhouse gas mitigation policies (Representative Concentration Pathways - RCPs). This work was conducted on a supralittoral habitat situated in Genova (Ligurian Sea), and has covered an eventual change of environmental conditions driven by SLR, which might impact the Culicid Acartomyiamariae, a resident species. The wave run-up stemming from the different RCPs was simulated using the XBeach model, and to infer SLR effects on A. mariae life cycle; the results were coupled with data obtained from field surveys. The model outputs highlighted a variation in the wave run-up oscillations under common wave conditions, which might affect the supralittoral area in terms of water input and hydric balance, and the A. mariae life cycle, which is highly dependent on temperature and salinity.","PeriodicalId":9116,"journal":{"name":"Bollettino della Societa italiana di biologia sperimentale","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81182684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Dozie-Nwakile, C. Nwakile, I. Uchendu, H. Okoroiwu, N. Onyemelukwe
Many years ago most human infections caused by aerobic Streptococci, were attributed to Lancefield groups A and D or to the so called non-groupable viridans Streptococci. The first human isolates of the group B Streptococci (GBS) were isolated from the vagina of post-partum women. This study is aimed at assessing GBS colonization of some clinical and common non-clinical surfaces. This study utilized a total of 615 samples (300 clinicals and 315 non-clinicals). Samples were from neonates and women who were respectively seen at the Institute of Child Health, of the University of Nigeria Teaching Hospital and Amblim Reference Laboratory in Enugu. The 300 clinical samples were cultured from 119 pregnant and 79 non-pregnant women, 52 neonates and 25 infertile couples (50 individuals; 7 primary and 18 secondary infertility). All samples were cultured on a modified Islam medium and identification carried out using standard bacteriological methods. Characterizations of the GBS isolates were carried out using sodium hippurate reactions, aesculin reactions, Christie, Atkin Muchin – Patterson (CAMP) test and definite hydrolysis on blood agar. The overall GBS isolation of 15.8% was observed in the clinical and non-clinical surfaces assessed. For the clinical subjects, GBS colonization of 11.9%, 7.6%, 9.6% and 17.0% were observed in the pregnant women, non-pregnant women, neonates and couples admitted for infertility. Prevalence of GBS isolation on inflamed cattle udder and milk products were 4.0% and 83.3%, respectively. Gestational period was associated with GBS colonization in pregnant women. All the GBS isolates were susceptible to penicillin and methicillin while all were resistant to streptomycin, tetracycline and sulphafurazole. GBS colonization of vagina was found and this poses a risk for neonatal sepsis.
{"title":"Prevalence, characterization, antimicrobial susceptibility pattern and factors associated with group B Streptococci (Streptococcus agalactiae) from clinical and non- clinical sources in South-East Nigeria","authors":"O. Dozie-Nwakile, C. Nwakile, I. Uchendu, H. Okoroiwu, N. Onyemelukwe","doi":"10.4081/jbr.2022.9922","DOIUrl":"https://doi.org/10.4081/jbr.2022.9922","url":null,"abstract":"Many years ago most human infections caused by aerobic Streptococci, were attributed to Lancefield groups A and D or to the so called non-groupable viridans Streptococci. The first human isolates of the group B Streptococci (GBS) were isolated from the vagina of post-partum women. This study is aimed at assessing GBS colonization of some clinical and common non-clinical surfaces. This study utilized a total of 615 samples (300 clinicals and 315 non-clinicals). Samples were from neonates and women who were respectively seen at the Institute of Child Health, of the University of Nigeria Teaching Hospital and Amblim Reference Laboratory in Enugu. The 300 clinical samples were cultured from 119 pregnant and 79 non-pregnant women, 52 neonates and 25 infertile couples (50 individuals; 7 primary and 18 secondary infertility). All samples were cultured on a modified Islam medium and identification carried out using standard bacteriological methods. Characterizations of the GBS isolates were carried out using sodium hippurate reactions, aesculin reactions, Christie, Atkin Muchin – Patterson (CAMP) test and definite hydrolysis on blood agar. The overall GBS isolation of 15.8% was observed in the clinical and non-clinical surfaces assessed. For the clinical subjects, GBS colonization of 11.9%, 7.6%, 9.6% and 17.0% were observed in the pregnant women, non-pregnant women, neonates and couples admitted for infertility. Prevalence of GBS isolation on inflamed cattle udder and milk products were 4.0% and 83.3%, respectively. Gestational period was associated with GBS colonization in pregnant women. All the GBS isolates were susceptible to penicillin and methicillin while all were resistant to streptomycin, tetracycline and sulphafurazole. GBS colonization of vagina was found and this poses a risk for neonatal sepsis.","PeriodicalId":9116,"journal":{"name":"Bollettino della Societa italiana di biologia sperimentale","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90662431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Firouz Amraie, S. Mahfoozpour, S. Vahdat, S. Hesam
Performance design and appraisal makes the system intelligent and motivates people to show desirable behavior and is the main part of organizational policies formulation and implementation. Hence, this systematic review summarizes the current knowledge about performance appraisal models in the county health centers of Iran. In the present study, 13 electronic databases and search engines were searched for the relevant keywords from 2002 to 2020. The obtained English or Persian articles on Health issues were then discussed. The quality appraisal of all articles was performed using the CASP checklist. Out of a total of 2400 articles, 13 articles with relevant titles, abstracts, and texts were reviewed. Based on the results of this study, the components of the performance appraisal model include health improvement, accountability and fairness in financial participation, financing, service provision, resource production, and stewardship. Performance appraisal of health care systems helps health decision makers and politicians to be accountable for their decisions so that they can make better decisions to improve their actions. Therefore, it is possible to improve the performance of inefficient health centers in a more appropriate way by managing the health centers personnel more properly and using their power more correctly. As the establishment and implementation of a performance appraisal model of health centers can improve the provision of health services, the application of these components requires to be well-planned.
{"title":"Performance appraisal models in the county health centers of Iran: A systematic review","authors":"Firouz Amraie, S. Mahfoozpour, S. Vahdat, S. Hesam","doi":"10.4081/jbr.2022.10536","DOIUrl":"https://doi.org/10.4081/jbr.2022.10536","url":null,"abstract":"Performance design and appraisal makes the system intelligent and motivates people to show desirable behavior and is the main part of organizational policies formulation and implementation. Hence, this systematic review summarizes the current knowledge about performance appraisal models in the county health centers of Iran. In the present study, 13 electronic databases and search engines were searched for the relevant keywords from 2002 to 2020. The obtained English or Persian articles on Health issues were then discussed. The quality appraisal of all articles was performed using the CASP checklist. Out of a total of 2400 articles, 13 articles with relevant titles, abstracts, and texts were reviewed. Based on the results of this study, the components of the performance appraisal model include health improvement, accountability and fairness in financial participation, financing, service provision, resource production, and stewardship. Performance appraisal of health care systems helps health decision makers and politicians to be accountable for their decisions so that they can make better decisions to improve their actions. Therefore, it is possible to improve the performance of inefficient health centers in a more appropriate way by managing the health centers personnel more properly and using their power more correctly. As the establishment and implementation of a performance appraisal model of health centers can improve the provision of health services, the application of these components requires to be well-planned.","PeriodicalId":9116,"journal":{"name":"Bollettino della Societa italiana di biologia sperimentale","volume":"541 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78887590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mozzarella was identified as one of the most extensively consumed dairy products. The aim of this study was to investigate the effect of Hyssopus officinalis extract on microbial properties, antioxidant activity, and mozzarella storage. Ultrasound was applied to gain extract and tests, such as total phenolics, antioxidant attributes, and microbial investigation were accomplished. Physicochemical features, peroxide, sensory evaluation and microbial population were assessed on mozzarella including 0, 1.13 and 1.40 μg/ml Hyssopusofficinalis extract during 45 days. The highest phenolic content was observed in rosmarinic acid (60.33 ± 2.31 mg/g) and Listeria monocytogenes was recognized as the most resistant microorganism in Hyssopus officinalis. The physicochemical results were found to be standard and the lowest peroxide was detected in the sample with the highest extract amount (1.40 μg/ml) on the 45th day. The microbial evaluation showed that mentioned extract was effective to minimize survival of Escherichia coli and Listeria monocytogenes during storage. The reduction in contamination hazard of Escherichia coli almost 1 log CFU/mL was detected in treatment samples during storage. The Hyssopus officinalis extract was spotted as the most appropriate agent to improve functional and sensory properties of mozzarella.
{"title":"The rule of biological and microbial safety in Hyssopus officinalis extract for influencing mozzarella cheese functionality","authors":"M. Nouri","doi":"10.4081/jbr.2022.10272","DOIUrl":"https://doi.org/10.4081/jbr.2022.10272","url":null,"abstract":"Mozzarella was identified as one of the most extensively consumed dairy products. The aim of this study was to investigate the effect of Hyssopus officinalis extract on microbial properties, antioxidant activity, and mozzarella storage. Ultrasound was applied to gain extract and tests, such as total phenolics, antioxidant attributes, and microbial investigation were accomplished. Physicochemical features, peroxide, sensory evaluation and microbial population were assessed on mozzarella including 0, 1.13 and 1.40 μg/ml Hyssopusofficinalis extract during 45 days. The highest phenolic content was observed in rosmarinic acid (60.33 ± 2.31 mg/g) and Listeria monocytogenes was recognized as the most resistant microorganism in Hyssopus officinalis. The physicochemical results were found to be standard and the lowest peroxide was detected in the sample with the highest extract amount (1.40 μg/ml) on the 45th day. The microbial evaluation showed that mentioned extract was effective to minimize survival of Escherichia coli and Listeria monocytogenes during storage. The reduction in contamination hazard of Escherichia coli almost 1 log CFU/mL was detected in treatment samples during storage. The Hyssopus officinalis extract was spotted as the most appropriate agent to improve functional and sensory properties of mozzarella.","PeriodicalId":9116,"journal":{"name":"Bollettino della Societa italiana di biologia sperimentale","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82840106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Health-promoting behaviors and healthy lifestyle are the main strategies to preserve people's health. Considering the importance of the youth's health in promoting the society's health, the present study was conducted to investigate the health-promoting behaviors and their associated factors in 18-29year-old youth of Khorramabad city in 2020. In this cross-sectional study, 358 individuals aged 18 to 29 years living in Khorramabad city in the first half of 2020 were included. This research sample was selected using a stratified multistage random sampling method. First, Khorramabad city was divided into three regions: north, central, and south regions based on the urban map. Then, two therapeutic health centers, two recreation centers, two educational centers, two business centers, and two religious cultural centers were randomly selected from each region. After that, the eligible samples were selected to enter the study by applying the convenience sampling method from each of these centers proportional to the calculated sample size. The sample size was estimated to be 358 people. The data was analyzed using SPSS software version 19.0. Descriptive statistical methods, such as mean, standard deviation and ratios, and frequency percentages were used to describe the terms. In addition, independent-t test, one-way analysis of variance (ANOVA), and linear regression analysis were used to analyze data. The mean age of the study participants was 24.6 ± 2.6 years. Of the total participants in the study, 217 (60.6%) were male and the rest were female. The total mean score of health-promoting behaviors in participants of the study was 122.6±16.13 (achievable range: 52-208). Overall, the status of health-promoting behaviors was undesirable in 12% of participants, moderate in 87.4%, and desirable in 0.6%. In univariate analysis, the difference in the total score of health-promoting behaviors was statistically significant between the subjects by gender (PV = 0.002), marital status (0.049), education level (0.001), occupation (<0.001) and history of regular smoking (<0.001).In linear regression analysis, gender, marital status, education level, and occupation were the most important predictors of health-promoting behaviors in the participants of this study. Considering the pivotal role of youth in society, proper planning seems necessary to improve their performance in the area of health promotion.
{"title":"An investigation into the health-promoting behaviors and their associated factors in 18-29 year-old youth of Khorramabad city in 2020","authors":"K. Anbari, Pardis Ghanadi, Amir Hossein Bagheri","doi":"10.4081/jbr.2022.10445","DOIUrl":"https://doi.org/10.4081/jbr.2022.10445","url":null,"abstract":"Health-promoting behaviors and healthy lifestyle are the main strategies to preserve people's health. Considering the importance of the youth's health in promoting the society's health, the present study was conducted to investigate the health-promoting behaviors and their associated factors in 18-29year-old youth of Khorramabad city in 2020. In this cross-sectional study, 358 individuals aged 18 to 29 years living in Khorramabad city in the first half of 2020 were included. This research sample was selected using a stratified multistage random sampling method. First, Khorramabad city was divided into three regions: north, central, and south regions based on the urban map. Then, two therapeutic health centers, two recreation centers, two educational centers, two business centers, and two religious cultural centers were randomly selected from each region. After that, the eligible samples were selected to enter the study by applying the convenience sampling method from each of these centers proportional to the calculated sample size. The sample size was estimated to be 358 people. The data was analyzed using SPSS software version 19.0. Descriptive statistical methods, such as mean, standard deviation and ratios, and frequency percentages were used to describe the terms. In addition, independent-t test, one-way analysis of variance (ANOVA), and linear regression analysis were used to analyze data. The mean age of the study participants was 24.6 ± 2.6 years. Of the total participants in the study, 217 (60.6%) were male and the rest were female. The total mean score of health-promoting behaviors in participants of the study was 122.6±16.13 (achievable range: 52-208). Overall, the status of health-promoting behaviors was undesirable in 12% of participants, moderate in 87.4%, and desirable in 0.6%. In univariate analysis, the difference in the total score of health-promoting behaviors was statistically significant between the subjects by gender (PV = 0.002), marital status (0.049), education level (0.001), occupation (<0.001) and history of regular smoking (<0.001).In linear regression analysis, gender, marital status, education level, and occupation were the most important predictors of health-promoting behaviors in the participants of this study. Considering the pivotal role of youth in society, proper planning seems necessary to improve their performance in the area of health promotion.","PeriodicalId":9116,"journal":{"name":"Bollettino della Societa italiana di biologia sperimentale","volume":"89 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84456417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Flutamide is a non-steroidal anti-androgen drug effective in the management of prostatic carcinoma. The drug appears to be well tolerated with mild gastrointestinal adverse events and gynecomastia. Flutamide-induced hepatotoxicity may range from minor elevation in liver enzymes to hepatic failure. Here, we tried to discuss the possibility of hepatotoxicity induced by flutamide as antiandrogen therapy in a patient with prostatic adenocarcinoma. Here we present a 75-year-old man who commenced flutamide as a postoperative anti-androgen for prostatic adenocarcinoma for two months. He had markedly elevated levels of liver enzymes due to acute liver failure and subsequent multi-organ failure. The patient died after the failure of the resuscitation measures. The temporal relationship between the flutamide initiation and the emergence of hepatotoxicity is not clear, with a possible latency of 12-16 weeks. Careful monitoring of liver function test during flutamide therapy is essential to prevent serious hepatotoxicity.
{"title":"Flutamide-induced hepatotoxicity: A case report","authors":"O. Kassid, S. Odhaib, M. Altemimi","doi":"10.4081/jbr.2022.10371","DOIUrl":"https://doi.org/10.4081/jbr.2022.10371","url":null,"abstract":"Flutamide is a non-steroidal anti-androgen drug effective in the management of prostatic carcinoma. The drug appears to be well tolerated with mild gastrointestinal adverse events and gynecomastia. Flutamide-induced hepatotoxicity may range from minor elevation in liver enzymes to hepatic failure. Here, we tried to discuss the possibility of hepatotoxicity induced by flutamide as antiandrogen therapy in a patient with prostatic adenocarcinoma. Here we present a 75-year-old man who commenced flutamide as a postoperative anti-androgen for prostatic adenocarcinoma for two months. He had markedly elevated levels of liver enzymes due to acute liver failure and subsequent multi-organ failure. The patient died after the failure of the resuscitation measures. The temporal relationship between the flutamide initiation and the emergence of hepatotoxicity is not clear, with a possible latency of 12-16 weeks. Careful monitoring of liver function test during flutamide therapy is essential to prevent serious hepatotoxicity.","PeriodicalId":9116,"journal":{"name":"Bollettino della Societa italiana di biologia sperimentale","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87475690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Venturella, Chiara Schimmenti, Elvira Manzone, F. Mortillaro, Irene Mistretta, M. Giammanco, A. Liga, G. Cancellieri, Marina Teresi
In recent years energy drinks consumption has increased, due to their ability to improve physical and cognitive performance. Unfortunately, because of poor or incorrect information, people are not always aware of the harmful consequences of these drinks such as obesity, diabetes, hypertension, tachycardia until death. Therefore, we conducted a statistical survey in the Palermo area, submitting a paper questionnaire to 1003 people. Data analysis shows that: only 29% of the audience never consumed energy drinks, while 71% tried them at least once in their life, especially in adolescence; 81% never or rarely drink them, 14% drink them a few times a month, while 5% drink them several times a week. Energy drinks are mostly consumed in disco, sport and study contexts; 93% of respondents are aware of the risks caused by the excessive consumption of them; 91% know that it is not appropriate to associate them with alcohol, but 9% think it is better to mix them; 72% of interviewees know that people should never drink energy drink with alcohol, 13% do it only in the weekend, while 15% think it is appropriate to do whenever they want. In fact, 14% do not believe it is risky to take energy drinks together with alcohol, and 40% do not know whether it is risky or not, while 46% know it can be risky; 45% associate the idea of cigarettes with alcohol and energy drinks. In conclusion, it is appropriate to highlight their risks to prevent some fatal consequences.
{"title":"Statistical survey focused on diffusion and knowledge of energy drinks, conducted in Palermo","authors":"F. Venturella, Chiara Schimmenti, Elvira Manzone, F. Mortillaro, Irene Mistretta, M. Giammanco, A. Liga, G. Cancellieri, Marina Teresi","doi":"10.4081/jbr.2022.9414","DOIUrl":"https://doi.org/10.4081/jbr.2022.9414","url":null,"abstract":"In recent years energy drinks consumption has increased, due to their ability to improve physical and cognitive performance. Unfortunately, because of poor or incorrect information, people are not always aware of the harmful consequences of these drinks such as obesity, diabetes, hypertension, tachycardia until death. Therefore, we conducted a statistical survey in the Palermo area, submitting a paper questionnaire to 1003 people. Data analysis shows that: only 29% of the audience never consumed energy drinks, while 71% tried them at least once in their life, especially in adolescence; 81% never or rarely drink them, 14% drink them a few times a month, while 5% drink them several times a week. Energy drinks are mostly consumed in disco, sport and study contexts; 93% of respondents are aware of the risks caused by the excessive consumption of them; 91% know that it is not appropriate to associate them with alcohol, but 9% think it is better to mix them; 72% of interviewees know that people should never drink energy drink with alcohol, 13% do it only in the weekend, while 15% think it is appropriate to do whenever they want. In fact, 14% do not believe it is risky to take energy drinks together with alcohol, and 40% do not know whether it is risky or not, while 46% know it can be risky; 45% associate the idea of cigarettes with alcohol and energy drinks. In conclusion, it is appropriate to highlight their risks to prevent some fatal consequences.","PeriodicalId":9116,"journal":{"name":"Bollettino della Societa italiana di biologia sperimentale","volume":"66 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84708560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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