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The Histopathological Effect of Rotavirus in Small Intestine of Mice Isolated from Different Area of Iraq 轮状病毒对伊拉克不同地区小鼠小肠组织病理学的影响
Pub Date : 2018-01-25 DOI: 10.4172/2161-0517.1000172
Abdulazeez Aa, Al-Rawi As, Abdullah Wz, Abed Mn, F. Alhamadani, Aufi Im
A total of 125 fecal samples of infants with acute gastroenteritis were collected randomly from November 2015 to March 2016. Their ages ranged from two weeks to six months. Rotavirus was diagnosed with three detection kits as well as tissue culture. The present study results revealed that 59 (47.2%), 51(40.8%), and 44(35.2%) were positive using chromatographic immunoassay, ELISA, and PCR techniques, respectively. The histopathological changes in intestine at 2 days post infection showed congested diluted blood vessels with inflammatory cells particularly neutrophils and mononuclear cells and edema in sub mucosa in addition to necrosis of crypt and hypertrophy of goblet cells.
随机收集2015年11月至2016年3月婴幼儿急性胃肠炎患儿粪便样本125份。他们的年龄从两周到六个月不等。采用三种检测试剂盒和组织培养对轮状病毒进行诊断。本研究结果显示,采用层析免疫分析法、ELISA法和PCR法分别检测阳性59例(47.2%)、51例(40.8%)和44例(35.2%)。感染后2天的肠组织病理学改变显示血管充血稀释,炎症细胞,特别是中性粒细胞和单核细胞,粘膜下层水肿,隐窝坏死,杯状细胞肥大。
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引用次数: 1
program against cancer in afghanistan 阿富汗的抗癌项目
Pub Date : 2018-01-01 DOI: 10.29011/2688-8750.100006
El HadjiSeydouMbaye
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引用次数: 0
program against cancer in bhutan 不丹的抗癌项目
Pub Date : 2018-01-01 DOI: 10.29011/2688-8750.100013
E. Mbaye
Worldwide, one in eight deaths is due to cancer. Cancer causes more deaths than AIDS, tuberculosis, and malaria combined [1]. When countries are grouped according to economic development, cancer is the leading cause of death in developed countries and the second leading cause of death in developing countries [2]. Rates of cancers common in Western countries will continue to rise in developing countries if preventive measures are not widely applied [3-5]. Projections based on the GLOBOCAN 2012 estimates predict a substantive increase to 19.3 million new cancer cases per year by 2025, due to growth and ageing of the global population. Incidence has been increasing in most regions of the world, but there are huge inequalities between rich and poor countries. More than half of all cancers (56.8%) and cancer deaths (64.9%) in 2012 occurred in less developed regions of the world, and these proportions will increase further by 2025 [6]. By 2030, the global burden is expected to grow to 21.4 million new cancer cases and 13.2 million cancer deaths [7]. Rates of cancers will continue to rise by 2035 with 23,980,858 new cancer cases [3-5].
在世界范围内,每8例死亡中就有1例死于癌症。癌症造成的死亡人数比艾滋病、结核病和疟疾加起来还要多。如果按照经济发展程度对各国进行分组,癌症是发达国家的主要死因,是发展中国家的第二大死因。如果不广泛采取预防措施,西方国家常见的癌症在发展中国家的发病率将继续上升[3-5]。根据GLOBOCAN 2012估计的预测,到2025年,由于全球人口的增长和老龄化,每年新的癌症病例将大幅增加至1930万。在世界大多数地区,发病率一直在增加,但富国和穷国之间存在巨大的不平等。2012年,一半以上的癌症(56.8%)和癌症死亡(64.9%)发生在世界欠发达区域,到2025年这些比例将进一步增加。到2030年,全球癌症负担预计将增加到2140万新发癌症病例和1320万癌症死亡病例。到2035年,癌症发病率将继续上升,新发癌症病例将达到23980858例[3-5]。
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引用次数: 0
The Hygienic Importance of Fungi Colonizing the Sheep Wool in Erbil/Iraq 伊拉克埃尔比勒地区羊毛真菌的卫生意义
Pub Date : 2018-01-01 DOI: 10.4172/2161-0517.1000177
S. Al-Bader
Aims: The study was conducted to identify a non-dermatophytic fungi associated with wool hairs in Erbil city. The common and dominate fungal genera were recorded, as well as the hygienic importance of all isolates were reviewed. Materials and Methods: Wool samples were collected during February 2017. Pieces of wool hair were cultured on Sabouraud's dextrose agar. Cultured plates were incubated in room temperature. The growing fungi were counted and were identified microscopically. The occurrence % (O%), and the frequency of occurrence % (FQ%) for the identified genera were calculated. Results: A 22 fungal isolates belong to 16 genera beside one isolate of Actinomycetes were recognized. The Hyphomycetes represented in (10 genera 62.5%), they were (Alternaria, Aspergillus (5 sp), Scytelidium, Chrysosporium, Curvelaria, Cladosporium, Penecilium, Scpulariopsis, Fusarium and Ulocladium. Two genera belong to each of Ascomycetes and Zygomycetes (12.5%) include (Chaetomium, Pseudallescheria) and (Mucor, Rhizopus) respectively Basidiomycetes and Coelomycetes represent one genus (6.25%), they were Rhodotorula and phoma. Aspergillus showed the highest O% and FO% (88%; 32.9%) followed by Cladosporium (36%; 13.8%). Conclusion: The results showed that: 1-Hyphomycetes is predominant and Aspergillus is the common genus. 2- All the recorded fungi had an effects on human health. According to the previous studies their infections ranging from mild skin mycoses to serious deep infections. 3-A 81.25% of the recorded fungal genera in this study were previously isolated from upper respiratory tract of individuals have asthma and allergic symptoms in Iraq. 4-It is the first recorded of Rhodotorula mucilaginosa from wool samples in Iraq.
目的:对埃尔比勒市一种与羊毛有关的非皮肤真菌进行鉴定。记录了常见真菌属和优势真菌属,并对各菌株的卫生重要性进行了综述。材料与方法:2017年2月采集羊毛样品。在Sabouraud's葡萄糖琼脂上培养羊毛片。培养板在室温下孵育。对生长的真菌进行计数,并在显微镜下进行鉴定。计算鉴定属的发生% (O%)和发生频率% (FQ%)。结果:除1株放线菌外,共鉴定出16属22株真菌。菌丝菌共10属(62.5%),分别为Alternaria、Aspergillus(5属)、Scytelidium、Chrysosporium、Curvelaria、Cladosporium、Penecilium、Scpulariopsis、Fusarium和Ulocladium。子囊菌属和结合菌属各2属(12.5%),包括毛菌属(chetomium, Pseudallescheria)和毛霉菌属(Mucor, Rhizopus),担子菌属和腔菌属各1属(6.25%),分别为Rhodotorula和phoma。曲霉的O%和FO%最高(88%;32.9%),其次是枝孢菌(36%);13.8%)。结论:结果表明:1-丝孢菌属为优势菌属,曲霉属为常见菌属。所有记录的真菌都对人类健康有影响。根据以往的研究,它们的感染范围从轻微的皮肤真菌病到严重的深部感染。3-A本研究记录的真菌属中有81.25%是以前从伊拉克有哮喘和过敏症状的个体上呼吸道分离到的。4 .这是伊拉克首次从羊毛样品中记录到粘液红曲菌。
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引用次数: 2
Current Challenges in Hepatitis C Virus 当前丙型肝炎病毒面临的挑战
Pub Date : 2018-01-01 DOI: 10.4172/2161-0517.1000175
A. S, Gadepalli R
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引用次数: 0
Post-Earth Quake assessment of HEV prevalence among general population 地震后对一般人群中戊型肝炎患病率的评估
Pub Date : 2018-01-01 DOI: 10.4172/2161-0517.1000176
S. Khadka, Subhash Dhital, Baniya Jb, B. Shrestha, S. Tiwari, S. Poudel, S. Subedi, K. Kc, L. Shrestha, S. Mishra, R. Br, Upadhayay Bp, M. Sharma, Mahto Rm, G. Shakya
Hepatitis E virus (HEV) infection is a global disease causing acute hepatitis, transmitted by fecal contaminated water. In South East Asian countries like, Nepal Hepatitis E virus is a most common causative agent of sporadic viral hepatitis and outbreaks. The risk of viral hepatitis has escalated after April earth quake in Nepal. The study was done with the objective to find the prevalence of HEV specific IgM among the general population. Blood samples from 570 healthy populations were tested for HEV IgM by using the Wantai HEV-IgM ELISA, and 1.40% of the study population is found to be harboring the HEV IgM. The study fostered the low level exposure to virus with human reservoirs.
戊型肝炎病毒(HEV)感染是一种引起急性肝炎的全球性疾病,通过粪便污染的水传播。在东南亚国家,如尼泊尔,戊型肝炎病毒是散发的病毒性肝炎和疫情的最常见病原体。尼泊尔4月发生地震后,病毒性肝炎的风险有所上升。这项研究的目的是发现普通人群中HEV特异性IgM的患病率。使用万泰HEV-IgM ELISA对570名健康人群的血液样本进行HEV IgM检测,发现1.40%的研究人群携带HEV IgM。该研究促进了病毒与人类宿主的低水平接触。
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引用次数: 0
program against cancer in belize 伯利兹的抗癌项目
Pub Date : 2018-01-01 DOI: 10.29011/2688-8750.100011
E. Mbaye
Worldwide, one in eight deaths is due to cancer. Cancer causes more deaths than AIDS, tuberculosis, and malaria combined [1]. When countries are grouped according to economic development, cancer is the leading cause of death in developed countries and the second leading cause of death in developing countries [2]. Rates of cancers common in Western countries will continue to rise in developing countries if preventive measures are not widely applied [3-5]. Projections based on the GLOBOCAN 2012 estimates predict a substantive increase to 19.3 million new cancer cases per year by 2025, due to growth and ageing of the global population. Incidence has been increasing in most regions of the world, but there are huge inequalities between rich and poor countries. More than half of all cancers (56.8%) and cancer deaths (64.9%) in 2012 occurred in less developed regions of the world, and these proportions will increase further by 2025 [6]. By 2030, the global burden is expected to grow to 21.4 million new cancer cases and 13.2 million cancer deaths [7]. Rates of cancers will continue to rise by 2035 with 23,980,858 new cancer cases [3-5].
在世界范围内,每8例死亡中就有1例死于癌症。癌症造成的死亡人数比艾滋病、结核病和疟疾加起来还要多。如果按照经济发展程度对各国进行分组,癌症是发达国家的主要死因,是发展中国家的第二大死因。如果不广泛采取预防措施,西方国家常见的癌症在发展中国家的发病率将继续上升[3-5]。根据GLOBOCAN 2012估计的预测,到2025年,由于全球人口的增长和老龄化,每年新的癌症病例将大幅增加至1930万。在世界大多数地区,发病率一直在增加,但富国和穷国之间存在巨大的不平等。2012年,一半以上的癌症(56.8%)和癌症死亡(64.9%)发生在世界欠发达区域,到2025年这些比例将进一步增加。到2030年,全球癌症负担预计将增加到2140万新发癌症病例和1320万癌症死亡病例。到2035年,癌症发病率将继续上升,新发癌症病例将达到23980858例[3-5]。
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引用次数: 0
HBV and HCV Seroprevalence and the Predominant HCV Genotypes in a Hospital Setting in Cameroon 喀麦隆一家医院中HBV和HCV的血清患病率和主要HCV基因型
Pub Date : 2018-01-01 DOI: 10.4172/2161-0517.1000178
Marceline Dn, Gaëlle Fka, N. Julius, Paul Mf
Infectious diseases are a substantial threat to global health. Hepatitis viral infections are life threatening infections, responsible for most liver cirrhosis and cancers. In order to determine the seroprevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections; as well as the HCV genotypes of the collected isolates, a study was conducted at a hospital setting in Cameroon. Enzyme immunoassays were used for HBV and HCV screening tests; HCV genotypes and subtypes were determined using standard molecular biology and genomic techniques that involved RT-PCR, gene cloning, DNA sequencing, and bioinformatics tools. The results showed that 14.15% of the study populations were screened HBV positive; whereas 24.82% were diagnosed HCV positive. The seroprevalence was higher in men: 12.75% and 16.1% respectively for HBV and HCV infections. The majority of HBV infected were younger, whereas HCV infected people were older. HCV genotypes 1 and 4 were identified.These findings are useful for policy making in Cameroon. Furthermore, the HCV clones generated in the present study might constitute useful and representative molecular tools for vaccine and drug development.
传染病是对全球健康的重大威胁。肝炎病毒感染是危及生命的感染,是导致大多数肝硬化和癌症的原因。为了确定乙型肝炎病毒(HBV)和丙型肝炎病毒(HCV)感染的血清患病率;除了收集到的分离株的HCV基因型外,还在喀麦隆的一家医院环境中进行了一项研究。酶免疫法用于HBV和HCV筛查试验;采用标准分子生物学和基因组技术,包括RT-PCR、基因克隆、DNA测序和生物信息学工具,确定HCV基因型和亚型。结果显示,14.15%的研究人群HBV筛查呈阳性;而HCV阳性的占24.82%。男性的血清患病率更高:HBV和HCV感染分别为12.75%和16.1%。HBV感染者多为年轻人,而HCV感染者多为老年人。HCV基因型为1型和4型。这些发现对喀麦隆的政策制定很有帮助。此外,本研究中生成的HCV克隆可能成为疫苗和药物开发的有用和有代表性的分子工具。
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引用次数: 3
program against cancer in jordan 约旦的抗癌项目
Pub Date : 2018-01-01 DOI: 10.29011/2688-8750.100005
E. Mbaye
Worldwide, one in eight deaths is due to cancer. Cancer causes more deaths than AIDS, tuberculosis, and malaria combined [1]. When countries are grouped according to economic development, cancer is the leading cause of death in developed countries and the second leading cause of death in developing countries [2]. Rates of cancers common in Western countries will continue to rise in developing countries if preventive measures are not widely applied [3-5]. Projections based on the GLOBOCAN 2012 estimates predict a substantive increase to 19.3 million new cancer cases per year by 2025, due to growth and ageing of the global population. Incidence has been increasing in most regions of the world, but there are huge inequalities between rich and poor countries. More than half of all cancers (56.8%) and cancer deaths (64.9%) in 2012 occurred in less developed regions of the world, and these proportions will increase further by 2025 [6]. By 2030, the global burden is expected to grow to 21.4 million new cancer cases and 13.2 million cancer deaths [7]. Rates of cancers will continue to rise by 2035 with 23,980,858 new cancer cases [3-5].
在世界范围内,每8例死亡中就有1例死于癌症。癌症造成的死亡人数比艾滋病、结核病和疟疾加起来还要多。如果按照经济发展程度对各国进行分组,癌症是发达国家的主要死因,是发展中国家的第二大死因。如果不广泛采取预防措施,西方国家常见的癌症在发展中国家的发病率将继续上升[3-5]。根据GLOBOCAN 2012估计的预测,到2025年,由于全球人口的增长和老龄化,每年新的癌症病例将大幅增加至1930万。在世界大多数地区,发病率一直在增加,但富国和穷国之间存在巨大的不平等。2012年,一半以上的癌症(56.8%)和癌症死亡(64.9%)发生在世界欠发达区域,到2025年这些比例将进一步增加。到2030年,全球癌症负担预计将增加到2140万新发癌症病例和1320万癌症死亡病例。到2035年,癌症发病率将继续上升,新发癌症病例将达到23980858例[3-5]。
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引用次数: 0
3D8 Single Chain Variable Fragment Transgenic Chickens Inhibit the Spread of Infectious Bronchitis Virus via Nuclease Activity 3D8单链可变片段转基因鸡通过核酸酶活性抑制传染性支气管炎病毒的传播
Pub Date : 2018-01-01 DOI: 10.4172/2161-0517.1000181
B. Sj, G. Lee, H. Choi, Jung Sk, Kim Js, Oh Kb, Kim Kw, H. Yang, Kim Dh
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引用次数: 0
期刊
Virology & mycology : infectious diseases
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